A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Lenalidomide N(imido)-Glucoside is a derivative of Lenalidomide; an immunomodulatory drug and analog of Thalidomide. Synonyms: 3-(4-Amino-1-oxoisoindolin-2-yl)-1-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)piperidine-2,6-dione. Molecular formula: C19H23N3O8. Mole weight: 421.4.
Lenalidomide (Standard)
Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R.
Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor. Leniolisib has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173. CAS No. 1354690-24-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17635.
Leniolisib
Leniolisib is a PI3K (phosphatidylinositol 3-kinase) inhibitor. No detailed information has been published yet. Synonyms: (S)-1-(3-((6-(6-methoxy-5-(trifluoromethyl)pyridin-3-yl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)propan-1-one;UNII-L22772Z9CP. Grades: 98%. CAS No. 1354690-24-6. Molecular formula: C21H25F3N6O2. Mole weight: 450.46.
Leniolisib phosphate
Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. Leniolisib phosphate has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173 phosphate. CAS No. 1354691-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17635A.
Lenoremycin
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A-130A; A-130A; Antibiotic Ro 21 6150; Dianemycin, 10-demethyl-19-de[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy]-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, [11(2R,5S,6R),12R]-; 6-Nonenoic acid, 8-[2,4',10,10'-tetramethyl-2'-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9-[(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy][2,7'-bi-1,6-dioxaspiro[4.5]dec]-7-yl]-2,4,6-trimethyl-5-oxo-, [2S-[2a[2'S*, 4'R*, 5'S*, 7'S*[2R*, 5S*, 7R*(2R*, 4S*, 6E, 8R*), 9S*(2S*, 5R*, 6S*), 10S*], 10'S*], 3b, 5b, 6b]]-. CAS No. 51257-84-2. Molecular formula: C47H78O13. Mole weight: 851.11.
Lenoremycin sodium
It is a polyether antibiotic produced by the strain of Streptomyces hygroscopicus A-130. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and can be used as a feed additive to control Eimeriatenella infection. Synonyms: Antibiotic A130 sodium salt; Dianemycin, 10-demethyl-19-de((tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)oxy)-12-methyl-11-O-(tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl)-, monosodium salt, (11(2R,5S,6R),12R)-; Antibiotic A-130A Sodium salt. CAS No. 58399-44-3. Molecular formula: C47H77NaO13. Mole weight: 873.10.
Lenperone
Lenperone is a neuroleptic butyrophenone. Lenperone is an effective atypical antipsychotic drug used in the treatment of schizophrenia. Group: Biochemicals. Alternative Names: 4-[4-(4-Fluorobenzoyl)-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone. Grades: Highly Purified. CAS No. 24678-13-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Lensiprazine
Lensiprazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: lensiprazine;(2R)-8-[4-[3-(5-Fluoro-1H-indol-3-yl)propyl]-1-piperazinyl]-2-methyl-2H-1,4-benzoxazin-3(4H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 327026-93-7. Molecular formula: C24H27FN4O2. Mole weight: 422.5. Density: 1.262. Product ID: ACM327026937. Alfa Chemistry ISO 9001:2015 Certified.
Lensiprazine
Lensiprazine is a potent in vitro dopamine receptor antagonist and highly active as serotonin reuptake inhibitor. Uses: D(2) receptor antagonist. Synonyms: SLV-314; SLV 314; SLV314; (2R)-8-[4-[3-(5-Fluoro-1H-indol-3-yl)propyl]-1-piperazinyl]-2-methyl-2H-1,4-benzoxazin-3(4H)-one. Grades: ≥98%. CAS No. 327026-93-7. Molecular formula: C24H27FN4O2. Mole weight: 422.50.
Lenthionine
Lenthionine is a marine derived natural products found in Chondria acrorhizophora. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,2,3,5,6-Pentasulfur-cylloheptane. CAS No. 292-46-6. Molecular formula: C2H4S5. Mole weight: 188.4. Purity: 95%+. IUPACName: 1,2,3,5,6-Pentathiepane. Canonical SMILES: C1SSCSSS1. Density: 1.483 g/cm³. Product ID: ACM292466. Alfa Chemistry ISO 9001:2015 Certified.
1,6-branched b-1,3-glucan (2 branches for every 5 b-1,3-glucose residues). CAS No. 37339-90-5. Product ID: 4-00558. Properties: granule size <0.2 mm, ash <1.0%, degree of deacetylation>80%. Source : from crab shells.
Lentinan
Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering [1][4]. Uses: Scientific research. Group: Natural products. CAS No. 37339-90-5. Pack Sizes: 100 mg. Product ID: HY-N6653.
Lentinan
Lentinan. Group: Biochemicals. Grades: Highly Purified. CAS No. 37339-90-5. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: (C42H70O35)n. US Biological Life Sciences.
Worldwide
Lentinan
Lentinan is a polysaccharide with antitumor effects. Uses: Adjuvants, immunologic. Synonyms: A823605; Bromoduline. CAS No. 37339-90-5. Molecular formula: (C42H72O36)n. Mole weight: 1153.
Lenvatinib
Lenvatinib (E7080) is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/&beta. Synonyms: 4-[3-chloro-4-[[ (cyclopropylamino) carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide; E-7080; E 7080; E7080; ER-203492-00. Grades: >98%. CAS No. 417716-92-8. Molecular formula: C21H19ClN4O4. Mole weight: 426.85.
Lenvatinib
Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3 , FGFR1-4 , PDGFR , KIT , and RET , shows potent antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7080. CAS No. 417716-92-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10981.
Lenvatinib Liposome
Lenvatinib is a type I tyrosine kinase inhibitor that exhibits potent anti-angiogenic activity in cancer therapy. This product is a pre-formulated liposome encapsulating Lenvatinib. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes.
Lenvatinib mesylate
Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3 , FGFR1-4 , PDGFR , KIT , and RET , shows potent antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7080 mesylate. CAS No. 857890-39-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-10981A.
Lenvatinib N-Oxide
One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/&beta. Synonyms: 6-Carbamoyl-4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline 1-Oxide; 4-[3-Chloro-4-[[ (cyclopropylamino) carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide 1-Oxide; Lenvatinib Impurity 10. CAS No. 1788901-86-9. Molecular formula: C21H19ClN4O5. Mole weight: 442.85.
Lenvervimab
Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GC1102. CAS No. 2055006-79-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99693.
Lenzilumab
Lenzilumab is a humanized monoclonal antibody targeting colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF). Lenzilumab has the potential for the treatment of COVID-19. Synonyms: KB 003; KB003; KB-003. CAS No. 1229575-09-0.
Lenzilumab
Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KB 003. CAS No. 1229575-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99207.
LEO29102
LEO29102 is a potent, selective, and soft-drug phosphodiesterase 4 (PDE4) inhibitor. It shows properties suitable for patient-friendly formulations giving efficient drug delivery to the skin. It may be useful for treatment of dermatological diseases and atopic dermatitis. It was developed by Neochem Pharmaceutical and in clinic phase 2 trials. Uses: Leo29102 may be useful for treatment of dermatological diseases and atopic dermatitis. Synonyms: LEO-29102; LEO 29102; LEO29102. 2-(6-(2-(3,5-dichloropyridin-4-yl)acetyl)-2,3-dimethoxyphenoxy)-N-propylacetamide. Grades: >98 %. CAS No. 1035572-38-3. Molecular formula: C20H22Cl2N2O5. Mole weight: 441.31.
Leonurine
Leonurine. Group: Biochemicals. Alternative Names: 4-Guanidinobutyl syringate. Grades: Plant Grade. CAS No. 24697-74-3. Pack Sizes: 20mg. Molecular Formula: C14H21N3O5, Molecular Weight: 311.334. US Biological Life Sciences.
Worldwide
Leonurine
Leonurine is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198. CAS No. 24697-74-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741.
Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198 hydrochloride. CAS No. 24735-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741A.
Leonurine Hydrochloride
Leonurine Hydrochloride. Group: Biochemicals. Grades: Plant Grade. CAS No. 24735-18-0. Pack Sizes: 20mg. Molecular Formula: C14H22ClN3O5, Molecular Weight: 347.8. US Biological Life Sciences.
Worldwide
LEP (116-130) (mouse)
LEP (116-130) (mouse). Group: Biochemicals. Grades: Purified. CAS No. 258276-95-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
LEP (116-130) (mouse) TFA
LEP (116-130) (mouse) TFA is a synthetic leptin peptide fragment. Synonyms: Leptin Fragment 116-130 Amide mouse TFA; LEP(116-130) (mouse) TFA; H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2.TFA; L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-glycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide trifluoroacetic acid; L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-, 2,2,2-trifluoroacetate (1:1). Grades: ≥95%. CAS No. 2828433-16-3. Molecular formula: C66H110F3N19O26S. Mole weight: 1674.77.
Lepidine,2-(2-aminoethoxy)-(8ci)
Lepidine,2-(2-aminoethoxy)-(8ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Lepidine, 2-(2-aminoethoxy)- (8CI). Product Category: Heterocyclic Organic Compound. CAS No. 802570-92-9. Molecular formula: C12H14N2O. Mole weight: 202.25236. Product ID: ACM802570929. Alfa Chemistry ISO 9001:2015 Certified.
Lepidine (4-Methylquinoline)
25g Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C10H9N. CAS No. 491-35-0. Prepack ID 40487028-25g. Molecular Weight 143.19. See USA prepack pricing.
Lepimectin A4
Lepimectin A4 is a component of the insecticide lepimectin and a synthetic macrocyclic lactone. Synonyms: (6R,13R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-13-[[(methoxyimino)phenylacetyl]oxy]-milbemycin B. Grades: >95% by HPLC. CAS No. 171249-05-1. Molecular formula: C41H53NO10. Mole weight: 719.86.
L-(-)-Epinephrine
Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. Group: Biochemicals. Alternative Names: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; (R)-Epinephrine; Renoform; Renostypticin; Adnephrine; Adrenal; Adrenalin; Adrenaline; l-Epinephrine; Levoepinephrine. Grades: Highly Purified. CAS No. 51-43-4. Pack Sizes: 100mg. US Biological Life Sciences.
a,b-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-42-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
L-(-)-Epinephrine-d3
Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. Group: Biochemicals. Alternative Names: 4-[(1R)-1-Hydroxy-2-(methylamino-d3)ethyl]-1,2-benzenediol; (R)-Epinephrine-d3; Renoform-d3; Renostypticin-d3; Adnephrine-d3; Adrenal-d3; Adrenalin-d3; Adrenaline-d3; l-Epinephrine-d3; Levoepinephrine-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Lepirudin
Lepirudin is an anticoagulant that acts as a direct thrombin inhibitor. Lepirudin binds to both free and clot-bound thrombin. Lepirudin is approved for the treatment of heparin-induced thrombocytopenia (HIT). Uses: The treatment of heparin-induced thrombocytopenia (hit). Synonyms: (Leu1,Thr2)-Hirudin (desulfated); Lepirudin; Refludan; Refludin; Hbw 023; Hbw-023; Hbw023. CAS No. 138068-37-8. Molecular formula: C287H440N80O111S6. Mole weight: 6979.41.
Leprapinic acid
Leprapinic acid is a member of methoxybenzenes. Synonyms: Leprapic acid; methyl (E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-(2-methoxyphenyl)acetate; Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (E)-; α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester; Benzeneacetic acid, α-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (αE)-; [3-Hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-(2-methoxy-phenyl)-acetic acid methyl ester. CAS No. 481-59-4. Molecular formula: C20H16O6. Mole weight: 352.34.
2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Synonyms: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33.
Leprolomin
It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Synonyms: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grades: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38.
Leptin (116-130) (human)
Leptin (116-130) (human) is a fragment of human leptin, which is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: Obese Gene Peptide (116-130) (human); L-Serine, L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-serylglycyl-L-leucyl-L-α-glutamyl-L-threonyl-L-leucyl-L-α-aspartyl-; H-Ser-Cys-His-Leu-Pro-Trp-Ala-Ser-Gly-Leu-Glu-Thr-Leu-Asp-Ser-OH; L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-seryl-glycyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-serine. Grades: ≥95%. CAS No. 2243207-12-5. Molecular formula: C70H106N18O24S. Mole weight: 1615.76.
Leptin(150-167)(human)
Leptin(150-167)(human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: LEU-GLN-GLY-SER-LEU-GLN-ASP-MET-LEU-TRP-GLN-LEU-ASP-LEU-SER-PRO-GLY-CYS;LEPTIN (150-167) (HUMAN);LEPTIN FRAGMENT 150-167 HUMAN;H-LEU-GLN-GLY-SER-LEU-GLN-ASP-MET-LEU-TRP-GLN-LEU-ASP-LEU-SER-PRO-GLY-CYS-OH;OBESE GENE PEPTIDE (150-167) (HUMAN);Obese Gene. Product Category: Heterocyclic Organic Compound. CAS No. 200436-46-0. Molecular formula: C87H138N22O28S2. Mole weight: 2004.29. Purity: 0.96. IUPACName: LEPTIN (150-167) (HUMAN). Canonical SMILES: CC(C)CC(C(=O)NC(CCC(=O)N)C(=O)NCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CCSC)C(=O)NC(CC(C)C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N3CCCC3C(=O)NCC(=O)NC(CS)C(=O)O)N. Product ID: ACM200436460. Alfa Chemistry ISO 9001:2015 Certified.
Leptin (22-56), human
Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Synonyms: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grades: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49.
Leptin Fragment 116-130 Amide mouse
A synthetic leptin peptide fragment. Synonyms: LEP 116-130. Grades: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73.
Leptin (human)
Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Synonyms: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grades: ≥95% by HPLC. CAS No. 177404-21-6.
Leptocillin
Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Synonyms: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Leptofuranin A
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72.
Leptofuranin B
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75.
Leptofuranin C
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70.
Leptofuranin D
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73.
Leptoglycin
Leptoglycin is an antibacterial peptide isolated from Leptodactylus pentadactylus. Leptoglycin was able to inhibit the growth of Gram-negative bacteria Pseudomonas aeruginosa, Escherichia coli and Citrobacter freundii with minimal inhibitory concentrations (MICs) of 8 microM, 50 microM, and 75 microM respectively, but it did not show antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis), yeasts (Candida albicans and Candida tropicalis) and dermatophytes fungi (Microsporum canis and Trichophyton rubrum). Synonyms: Gly-Leu-Leu-Gly-Gly-Leu-Leu-Gly-Pro-Leu-Leu-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Leu-Leu.
Leptolstatin
It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Synonyms: 2H-Pyran-2-one, 6-[(1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxo-1, 3, 7, 9, 17-nonadecapentaen-1-yl]-5, 6-dihydro-, (6R)-; (R)-6-((1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxononadeca-1, 3, 7, 9, 17-pentaen-1-yl)-5, 6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69.
Leptomycin A
a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Synonyms: Jildamycin; Antibiotic ATS 1287A; Antibiotic PD 118607; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-. Grades: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C32H46O6. Mole weight: 526.71.
Leptomycin A
from Streptomyces sp., ~95% (HPLC), methanol solution. Group: Fluorescence/luminescence spectroscopy.
Leptomycin A (Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin)
Leptomycin A, a methyl (cf. ethyl) analogue of Leptomycin B, is a minor component of the leptomycin complex produced by selected Streptomyces species. Leptomycin B is a potent inhibitor of the nuclear transport receptor CRM1. Leptomycin A is also likely to inhibit nuclear transport and may offer differences in exporter selectivity. Leptomycin A shows antimicrobial activity against Schizosaccaromyces pombe and Mucor rouxianus. Group: Biochemicals. Alternative Names: Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin. Grades: Highly Purified. CAS No. 87081-36-5. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Leptomycin B
Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16909.
Leptomycin B (Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin)
Leptomycin B is the dominant and most studied member of the leptomycin class isolated from selected Streptomyces strains. Leptomycin B is a nanomolar active and specific nuclear export inhibitor. Its target is CRM1/exportin1 a protein in the nuclear export sequence (NES). Examples of proteins affected are c-Abl, cyclin B1, HIV-1 Rev, IκB, MPF, MAP/ERK, MDM2/p53, NF-κB/IκB7 and PKA. Export of many RNAs are also inhibited e.g. COX-2 and c-FOS mRNA. In addition Leptomycin B shows antifungal and antibacterial and potent antitumour activities. Group: Biochemicals. Alternative Names: Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin. Grades: Highly Purified. CAS No. 87081-35-4. Pack Sizes: 500ug. US Biological Life Sciences.
Leptomycin B (LepB) is a potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus. Group: Biochemicals. Grades: Highly Purified. CAS No. 87081-35-4. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Leptomycin b from streptomyces sp
Leptomycin b from streptomyces sp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leptomycin B, Elactocin, Probes1_000170, Probes2_000132, NSC364372, CID5458861, 87081-35-4, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-, 2,10,12,16,18-Nonadecaptentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-. Product Category: Heterocyclic Organic Compound. Appearance: White crystalline solid. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.736. Purity: Purity >95% (HPLC). IUPACName: (2E,10E,12E,16E,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid. Density: 1.072 g/cm³. Product ID: ACM87081354. Alfa Chemistry ISO 9001:2015 Certified.
Leptosin I
It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5ab, 10ba, 10cS*, 15ab, 18b, 22ab, 22ba, 23aa, 24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptosin J
It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18, 22a-(Iminomethano)-10b, 23a-methano-10bH, 23aH-indolo[2'', 3'':2', 3'][1, 2, 3, 4, 6]tetrathiazocino[6'', 5'':1', 5']pyrrolo[3', 4':6, 7]pyrazino[2''', 1''':2, 3][1, 3]oxazepino[4, 5-b]indole-1, 4, 17, 25(18H)-tetrone, 2, 3, 5a, 6, 15, 15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2, 26-dimethyl-18-(1-methylethyl)-, (3a, 5aa, 10bb, 10cR*, 15aa, 18a, 22aa, 22bb, 23ab, 24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptospermone
Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with an IC 50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 567-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114991.
LEQ-506
an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Uses: Solid tumors. Synonyms: (R)-2-(5-(4-(6-benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol. Grades: > 95%. CAS No. 1204975-42-7. Molecular formula: C25H32N6O. Mole weight: 432.57.
Lercanadipine
Lercanidipine hydrochloride, a dihydropyridine compound, is a third generation calcium channel antagonist which shows longer duration of action of the past two generations' in the treatment of mild-to-moderate hypertension. Uses: Lercanidipine hydrochloride is a third generation calcium channel antagonist which shows longer duration of action of the past two generations' in the treatment of mild-to-moderate hypertension. Synonyms: Lercanidipine; Lercanidipine; masnidipine; Lercanil; Lercanidipine. Grades: >98%. CAS No. 100427-26-7. Molecular formula: C36H41N3O6. Mole weight: 611.73.
Lercanidipine
Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine- calcium channel blocker with a pIC 50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612.
Lercanidipine-d3 hydrochloride
Lercanidipine-d 3 (hydrochloride) is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189954-18-4. Pack Sizes: 1 mg. Product ID: HY-B0612DS1.