A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Peimine. Group: Biochemicals. CAS No. 23496-41-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Peimine
Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Verticine; Dihydroisoimperialine. CAS No. 23496-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0212.
Peiminine
Peiminine is an alkaloid isolated from Fritillaria. Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. Peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL. Uses: Moistening lung. Synonyms: Verticinone; Raddeanine. Grade: >98%. CAS No. 18059-10-4. Molecular formula: C27H43NO3. Mole weight: 429.64.
Peiminine
Peiminine is a compound that can be isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family). Peiminine can induce apoptosis in human hepatocellular carcinoma HepG2 cells through both extrinsic and intrinsic apoptotic pathways. Peiminine has anti-inflammatory, anticancer, anti-osteoporosis, cardioprotective and other activities in many animal models[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Verticinone; Raddeanine. CAS No. 18059-10-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N0213.
Peiminine
Peiminine. Group: Biochemicals. CAS No. 18059-10-4. Pack Sizes: 5mg. US Biological Life Sciences.
PEI Transfection Reagent is an optimized, linear polyethylenimine based formulation. This chemically synthesized product contains no animal-derived ingredients, is suitable for both small-scale and large-scale applications and. Because it is cost-effective, highly scalable and has high transfection efficiency and low cytotoxicity, it has become the industry standard for transient gene expression in high-performance cell lines. Applications: Pei transfection reagent is used for scalable gene delivery applications, including efficient co-transfection of multiple plasmids. main applications are for the production of recombinant virus vectors and for the rapid, transient expression of recombinant proteins and antibodies in established cell lines. Category: Biochemical reagents. Synonyms: Polyethyleneimine. Grades: DMF. Product ID: PIPB-0802. Appearance: Colorless liquid. Standard: Facility GMP.
Pelabresib
Pelabresib (CPI-0610) is a potent, selective, orally active and cell-active BET inhibitor. Pelabresib inhibits BRD4-BD1 with an IC50 of 39 nM, and with an EC50 value of 0.18 μM for MYC[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CPI-0610. CAS No. 1380087-89-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12863.
Pelacarsen
Pelacarsen (ISIS 681257) is a GalNAc3-conjugated 2-MOE-modified antisense oligonucleotide. Pelacarsen reduces apo (a)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AKCEA-APO(a)-LRx; ISIS 681257; TQJ230. CAS No. 1637637-70-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-151123.
Pelagiomicin A
It is produced by the strain of Pelagiobacter variabilis. It has strong activity against gram-positive bacteria and gram-negative bacteria, but no activity against candida albicans. It's cytotoxic to HeLa cells, BALB3T3 and BALB3T3/H-ras cultured in vivo with IC50 (μg/mL) of 0.04, 0.2 and 0.07, respectively. In vivo it has weak inhibitory effect on leukemia P388. Synonyms: Antibiotic 2088A; 3-Hydroxy-L-valine(6-carboxy-4-methoxy-1-phenazinyl)methylester; L-Valine, 3-hydroxy-, (6-carboxy-4-methoxy-1-phenazinyl)methyl ester; (S)-6-(((2-amino-3-hydroxy-3-methylbutanoyl)oxy)methyl)-9-methoxyphenazine-1-carboxylic acid. Grade: 95%. CAS No. 173485-80-8. Molecular formula: C20H21N3O6. Mole weight: 399.40.
Pelagiomicin B
It is produced by the strain of Pelagiobacter variabilis. Synonyms: Antibiotic 2088B; L-Valine, (6-carboxy-4-methoxy-1-phenazinyl)methyl ester. CAS No. 173485-81-9. Molecular formula: C20H21N3O5. Mole weight: 383.40.
Pelagiomicin C
It is produced by the strain of Pelagiobacter variabilis. It has the activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Antibiotic 2088C; Antibiotic B 4607A; Glycine, (6-carboxy-4-methoxy-1-phenazinyl)methyl ester. CAS No. 173485-82-0. Molecular formula: C17H15N3O5. Mole weight: 341.32.
PELARGONIC ACID. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
Isolated from the plant Salvia splendens (scarlet sage). Group: Enzymes. Synonyms: malonyl-CoA:anthocyanin 5-glucoside 4'''-O-malonyltransferase; Ss5MaT2. Enzyme Commission Number: EC 2.3.1.214. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2160; pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase; EC 2.3.1.214; malonyl-CoA:anthocyanin 5-glucoside 4'''-O-malonyltransferase; Ss5MaT2. Cat No: EXWM-2160.
Pelargonidin-3-O-glucoside chloride
Pelargonidin-3-O-glucoside chloride. Alternative Names: 3-(beta-D-Glucopyranosyloxy)-4',5,7-trihydroxyflavylium chloride. CAS No. 18466-51-8. Purity: >95.0%. Product ID: FFC-AR-18466518. Molecular formula: C21H21ClO10. Mole weight: 468.84. IUPAC Name: (2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxyphenyl)chromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol chloride. Alfa Chemistry - ISO 9001:32057 Certified.
Pelargonidin chloride is an anthocyanidin and also is a scavenger of nitric oxide radical and has antioxidant activities. Pelargonidin inhibits cell viability and induces cell cycle arrest at sub-G1 phase. Pelargonidin chloride increases the mRNA and protein expression of HO-1, NQO1, Nrf2. Pelargonidin chloride improves Aβ-induced memory and learning impairment[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 134-04-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-W011370.
Pelargonidin chloride
Pelargonidin chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 134-04-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C15H11ClO5. US Biological Life Sciences.
Worldwide
Pelargonidin (chloride)
Pelargonidin (chloride). Alternative Names: 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium, monochloride. CAS No. 134-04-3. Purity: >98.0%. Product ID: FFC-AR-134043. Molecular formula: C15H11ClO5. Mole weight: 306.7. IUPAC Name: 2-(4-hydroxyphenyl)chromenylium-3,5,7-triol chloride. Alfa Chemistry - ISO 9001:32057 Certified.
Pelcitoclax (APG-1252) is a potent Bcl-2/Bcl-xl inhibitor with antineoplastic and pro-apoptotic effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APG-1252. CAS No. 1619923-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109185.
PELCO 2 Layers Graphene Oxide TEM Support Films on(Carbon mesh, 5 pieces per box)
PELCO 2 Layers Graphene Oxide TEM Support Films on(Carbon mesh, 5 pieces per box). CAS No. 7440-44-0. Product ID: ACM7440440-178. Alfa Chemistry - ISO 9001:32057 Certified.
PELCO 2 Layers Graphene Oxide TEM Support Films on Lacey Carbon
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; Pelle
PELCO 6-8 layers CVD Graphene deposited on TEM Grids Lacey Carbon
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; Pel
PELCO Single Layer Graphene Oxide TEM Support Film(Carbon mesh, 5 pieces per box)
PELCO Single Layer Graphene Oxide TEM Support Film(Carbon mesh, 5 pieces per box). CAS No. 7440-44-0. Product ID: ACM7440440-179. Alfa Chemistry - ISO 9001:32057 Certified.
Pelgifatamab
Peligifatamab is a PSMA-targeted α-radioimmunoconjugate with an EC50 of 1.2 nM against human targets. Peligifatamab induces DNA damage, DNA double-strand breaks, cell cycle arrest and apoptosis (Apoptosis) in PSMA-positive prostate cancer cells. Peligifatamab reduces cell viability in a manner dependent on cellular PSMA expression levels. Peligifatamab inhibits tumor growth and tumor-induced abnormal bone growth in prostate cancer bone metastasis models. Peligifatamab exhibits antitumor efficacy in subcutaneous prostate cancer models and xenograft models. Peligifatamab can be used for the research of metastatic castration-resistant prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY-2315497; PSMA-TTC. CAS No. 2414550-93-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9992.
PELI1-IN-1
PELI1-IN-1 (compound 3d) is a potent inhibitor of PELI1, E3 ubiquitin ligase. PELI1-IN-1 has anti-tumPELI1-IN-1, a Resveratrol (HY-16561) derivative, is an orally active PELI1 Inhibitor (Kd = 8.2 μM). PELI1-IN-1 markedly interrupts the interaction of PELI1 and SNAIL/SLUG, and inhibits the K63-polyubiquitization of SNAIL/SLUG by PELI1, subsequently downregulating the protein levels of epithelial-mesenchymal transition (EMT) effectors SNAIL/SLUG. PELI1-IN-1 significantly reduces the level of SNAIL, SLUG and Vimentin without affecting the PELI1 expression. PELI1-IN-1 targets the FHA domain of PELI1 and disrupts the interaction, leading to the anti-metastasis of TNBC cells in vitro and in vivo. PELI1-IN-1 shows no evident toxicity in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034889-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157435.
Pelirine
Pelirine is isolated from the roots of Rauvolfia verticillata. Synonyms: 10-Methoxyepiaffinine. Grade: 96%. CAS No. 30435-26-8. Molecular formula: C21H26N2O3. Mole weight: 354.5.
Pelitinib
Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC50 of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282, 800, and 1255 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EKB-569; WAY-EKB 569. CAS No. 257933-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32718.
Pelitinib
A tyrosine kinase inhibitor; it is used to prepare formulation for treating primary or secondary cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 257933-82-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Pelitinib-d6
Labeled Pelitinib. A tyrosine kinase inhibitor; it is used to prepare formulation for treating primary or secondary cancer. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pe litrexol
Pelitrexol (AG 2037) is an inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), a purine biosynthetic enzyme. Pelitrexol also inhibits mTORC1 by reducing GTP-bound Rheb level, a mTORC1 obligate activator. Pelitrexol shows robust tumor growth suppression in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG 2037. CAS No. 446022-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14530.
Pellitorine
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H?-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18836-52-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3097.
Pellitorine
Cell-permeable. A natural product isolated from the roots of Piper Nigrum. Shows larvicidal, antimycobacterial and antituberculosis activity. Modulator of the sensory neuron function to induce tingling parethesia. Tingling-inducing agent. Excellent stable model compound for sensory studies. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Source:Synthetic. Originally isolated from roots of Anacyclus pryrethrum and fruits of Piper nigrum. Group: Biochemicals. Alternative Names: (E,E)-N-(2-Methylpropyl) 2,4-decadienamide, BRN 1725967. Grades: Highly Purified. CAS No. 18836-52-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C14H25NO, Molecular Weight: 223.4. US Biological Life Sciences.
Worldwide
Pelophylaxin-1
Pelophylaxin-1 is an antimicrobial peptide found in Rana fukienensis (Skin secretion, Pelophylax plancyi fukienensis, Fukien gold-striped pond frog), and has antimicrobial activity. Synonyms: Pelophylaxin 1. Grade: >98%. CAS No. 877458-36-1. Molecular formula: C131H232N36O39S2. Mole weight: 2999.62.
Pelophylaxin-2
Pelophylaxin-2 is an antimicrobial peptide found in Rana fukienensis (Skin secretion, Pelophylax plancyi fukienensis, Fukien gold-striped pond frog), and has antimicrobial activity. Synonyms: Pelophylaxin 2. Grade: >98%. CAS No. 877458-37-2. Molecular formula: C133H237N37O37S2. Mole weight: 3010.69.
Pelophylaxin-2GY
Pelophylaxin-2GY is an antimicrobial peptide found in Dark-spotted frogs, Pelophylax nigromaculatus, China, Asia. It has activity against gram-negative bacteria E. coli (MIC 2-4 μM). Synonyms: Pelophylaxin 2GY; Gly-Leu-Leu-Leu-Asp-Thr-Val-Lys-Gly-Ala-Ala-Lys-Asn-Val-Ala-Gly-Ile-Leu-Leu-Asn-Lys-Leu-Lys-Cys-Lys-Met-Thr-Gly-Asp-Cys. Grade: ≥97%.
Pelophylaxin-3
Pelophylaxin-3 is an antimicrobial peptide found in Rana fukienensis (Skin secretion, Pelophylax plancyi fukienensis, Fukien gold-striped pond frog), and has antimicrobial activity. Synonyms: Pelophylaxin 3. Grade: >98%. CAS No. 877458-38-3. Molecular formula: C144H255N39O45S3. Mole weight: 3349.03.
Pelophylaxin-4
Pelophylaxin-4 is an antimicrobial peptide found in Rana fukienensis (Skin secretion, Pelophylax plancyi fukienensis, Fukien gold-striped pond frog), and has antimicrobial activity. Synonyms: Pelophylaxin 4; Ile-Leu-Pro-Phe-Leu-Ala-Gly-Leu-Phe-Ser-Lys-Ile-Leu-NH2. Grade: >98%. CAS No. 877458-39-4. Molecular formula: C73H119N15O14. Mole weight: 1430.82.
Pelovaterin
Pelovaterin is an antimicrobial peptide found in Pelodiscus sinensis (Chinese softshell turtle, Trionyx sinensis), and has antibacterial activity against gram-negative bacteria Pseudomonas aeruginosa (EC50=0.42 μg/mL), Proteus vulgaris (EC50=0.37 μg/mL), Proteus mirabilis (EC50=8.4 μg/mL) and gram-positive bacterium Staphylococcus aureus (EC50=42 μg/mL). Grade: >98%. Molecular formula: C177H281N51O55S6. Mole weight: 4195.85.
Pelteobagrin
Pelteobagrin is an antimicrobial peptide isolated from Tachysurus fulvidraco (the skin mucus of Yellow catfish, Pelteobagrus fulvidraco Richardson), and has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Lys-Leu-Asn-Leu-Phe-Leu-Ser-Arg-Leu-Glu-Ile-Leu-Lys-Leu-Phe-Val-Gly-Ala-Leu. Grade: ≥95%. CAS No. 1314639-41-2. Molecular formula: C108H182N26O25. Mole weight: 2244.79.
Pemafibrate is a highly selective PPARα agonist, with an EC50 of 1 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R)-K-13675. CAS No. 848259-27-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17618.
Pemafibrate impurity 1
Pemafibrate impurity 1. Uses: For analytical and research use. CAS No. 848260-89-9. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB848260899.
Pembrolizumab (MK-3475) is a humanized IgG4 antibody inhibiting the programmed cell death 1 (PD-1) receptor, used in cancer immunotherapy. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-3475; Lambrolizumab. CAS No. 1374853-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9902.
Pembrolizumab (anti-PD-1)
Pembrolizumab (anti-PD-1) is a potent, highly selective, fully humanized immunoglobulin (Ig) G4-kappa monoclonal antibody against PD-1 with potential immune checkpoint inhibitory and antineoplastic activities. MW : 146.286 KD. Group: Antibodies. Alternative Names: MK-3475, lambrolizumab. CAS No. 1374853-91-4. Pack Sizes: 5mg. Product ID: A2005. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Pemetrexed
Pemetrexed (LY231514) is a novel antifolate and antimetabolite for thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT) with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively. Pemetrexed induces autophagy and apoptosis. Group: Inhibitors. Alternative Names: LY231514. CAS No. 137281-23-3. Pack Sizes: 25mg. Product ID: S5971. Formula: C20H21N5O6. Smiles: NC1=NC(=O)C2=C([NH]C=C2CCC3=CC=C(C=C3)C(=O)NC(CCC(O)=O)C(O)=O)N1. Storage Conditions: 3 years -20°C powder.
United States; Europe
Pemetrexed
Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: LY231514; Alimta; LY 231514; LY-231514. Grade: >98%. CAS No. 137281-23-3. Molecular formula: C20H21N5O6. Mole weight: 427.41.
Pemetrexed
Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY231514. CAS No. 137281-23-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10820.
Pemetrexed
Pemetrexed. Group: Biochemicals. Grades: Highly Purified. CAS No. 137281-23-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C20H21N5O6. US Biological Life Sciences.
Worldwide
Pemetrexed-[d5]
Pemetrexed-[d5], is the labelled analogue of Pemetrexed. Pemetrexed is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer. Synonyms: Pemetrexed D5. Grade: 95% by CP; 95% atom D. CAS No. 1129408-57-6. Molecular formula: C20H16D5N5O6. Mole weight: 432.44.
Pemetrexed-d5 Diethyl Ester
Isotope labelled Pemetrexed-d5 Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pemetrexed-d5, Disodium Salt (N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt)
Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Pemetrexed Diethyl Ester
Pemetrexed Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate. Grades: Highly Purified. CAS No. 146943-43-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Pemetrexed disodium
Pemetrexed disodium. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid sodium salt. Grades: Highly Purified. CAS No. 150399-23-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C20H19N5Na2O6. US Biological Life Sciences.
Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY231514 disodium. CAS No. 150399-23-8. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg; 200 mg. Product ID: HY-10820A.
Pemetrexed disodium EP Impurity A
Pemetrexed disodium EP Impurity A. Uses: For analytical and research use. Alternative Names: 869791-42-4(free base); (sodium (S)-2-(4-(2-(2-amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate. CAS No. 2243918-27-4. Molecular formula: C21H21N5Na2O6. Mole weight: 485.4. Catalog: APB2243918274.
Pemetrexed disodium hemipentahydrate
Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. Synonyms: L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt, hydrate; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt, hydrate (2:4:5); Ciambra; Pemetrexed disodium salt 2.5 hydrate; LY-231514 disodium hemipentahydrate; LY 231514 disodium hemipentahydrate; LY231514 disodium hemipentahydrate; Pemetrexed sodium hydrate (2:4:5); (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid, sodium salt 2.5 hydrate. Grade: >98%. CAS No. 357166-30-4. Molecular formula: C20H19N5Na2O6.5/2H2O. Mole weight: 516.42.
Pemetrexed disodium hemipenta hydrate
Pemetrexed (LY231514) disodium hemipenta hydrate is a CNS-penetrant antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY231514 disodium hemipenta hydrate. CAS No. 357166-30-4. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-13781.
Pemetrexed disodium heptahydrate
Pemetrexed disodium heptahydrate is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY231514 disodium heptahydrate. CAS No. 357166-29-1. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-10820B.
Pemetrexed Disodium Heptahydrate
Pemetrexed Disodium Heptahydrate. Group: Biochemicals. Alternative Names: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 10mg. Molecular Formula: C20H33N5Na2O13, Molecular Weight: 597.48. US Biological Life Sciences.