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| Product | Description | |
|---|---|---|
| PD 174265 | PD 174265 is a cell-permeable, reversible inhibitor of EGFR tyrosine kinase activity with IC50 value of 0.45 nM. Synonyms: 4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline; N-[4-(3-bromoanilino)quinazolin-6-yl]propanamide. Grades: ≥98%. CAS No. 216163-53-0. Molecular formula: C17H15BrN4O. Mole weight: 371.2. |  |
| PD 176252 | PD 176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively. PD 176252 inhibits proliferation of rat C6 glioma cells (IC50 = 2 μM) and inhibits NCI-H1299 xenograft proliferation in nude mice (IC50 = 5 μM). Synonyms: (S)-N-[[1-(5-Methoxy-2-pyridinyl)cyclohexyl]methyl]-α-methyl-α-[[[-(4-nitrophenyl)amino]carbonyl]amino-1H-indole-3-propanamide; PD-176252; PD 176252; PD176252. Grades: ≥98% by HPLC. CAS No. 204067-01-6. Molecular formula: C32H36N6O5. Mole weight: 584.67. | |
| PD 176252 | PD 176252. Group: Biochemicals. Grades: Purified. CAS No. 204067-01-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PD 176252 | PD 176252. CAS No: 204067-01-6 |  Sarchem Laboratories New Jersey NJ |
| PD180970 | PD180970 is a novel Bcr-Abl inhbiitor. PD180970 inhibited in vivo tyrosine phosphorylation of p210Bcr-Abl (IC50 = 170 nM) and the p210BcrAbl substrates Gab2 and CrkL (IC50 = 80 nM) in human K562 chronic myelogenous leukemic cells. In vitro, PD180970 potently inhibited autophosphorylation of p210Bcr-Abl (IC50 = 5 nM) and the kinase activity of purified recombinant Abl tyrosine kinase (IC50 = 2.2 nM). Incubation of K562 cells with PD180970 resulted in cell death. PD180970 is among the most potent inhibitors of the p210Bcr-Abl tyrosine kinase, which is present in almost all cases of human chronic myelogenous leukemia. PD180970 is a promising candidate as a novel therapeutic agent for Bcr-Abl-positive leukemia. Synonyms: PD 180970; PD-180970; PF-1515965; PF 1515965; PF1515965; 6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-. Grades: ≥95%. CAS No. 287204-45-9. Molecular formula: C21H15Cl2FN4O. Mole weight: 429.27. | |
| PD184161 | PD184161 is an orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner more effectively than PD098059 or U0126. PD184161 inhibited cell proliferation and induced apoptosis at concentrations of > or = 1.0 microM in a time- and concentration-dependent manner. PD184161 has antitumor effects in HCC in vitro and in vivo that appear to correlate with suppression of MEK activity. PD184161 is unable to suppress MEK activity in HCC xenografts in the long term. Synonyms: PD 184161; PD-184161; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide. CAS No. 212631-67-9. Molecular formula: C17H13BrClF2IN2O2. Mole weight: 557.56. | |
| PD 184161 | PD 184161. Group: Biochemicals. Alternative Names: 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-67-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H13BrClF2IN2O2. US Biological Life Sciences. | Worldwide |
| PD184352 | PD184352 / CI-1040 is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Group: Fluorinated apis. Alternative Names: CI-1040. CAS No. 212631-79-3. Molecular formula: C17H14ClF2IN2O2. Mole weight: 478.66. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Catalog: OFC212631793. |  |
| PD 184352 | PD 184352. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14ClF2IN2O2. US Biological Life Sciences. | Worldwide |
| PD-184352 | An inhibitor of ERK signaling pathway. A MAP kinase inhibitor. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 184,352 (2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040) | MEK (MAPKK) inhibitor. Potent and selective MAPK (ERK kinase 1; MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo). Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer. Group: Biochemicals. Alternative Names: 2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide, CI-1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H14ClF2IN2O2, Molecular Weight: 478.7. US Biological Life Sciences. | Worldwide |
| PD184352 (Cl-1040, 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide) | PD184352 is an inhibitor of mitogen activated protein kinase kinase (MEK or MAPKK). Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PD 198306 | PD 198306, an amino-benzamide compound, is an orally bioavailable and potent inhibitor of MAPK kinase 1/2 (MEK1/2; IC50=8 nM). It inhibits isolated enzyme at a concentration of 8 nM and inhibits MEK activity in synovial fibroblasts at concentrations of 30-100 nM. It is selective for MEK1/2 over ERK, c-Src, PI3Kγ, and cyclin-dependent kinases (IC50s = >1 μM). Synonyms: PD-198306; PD 198306; PD198306; N-(Cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]-benzamide. Grades: ≥98% by HPLC. CAS No. 212631-61-3. Molecular formula: C18H16F3IN2O2. Mole weight: 476.23. | |
| PD 198306 | PD 198306. Group: Biochemicals. Grades: Purified. CAS No. 212631-61-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD-1-IN-1 | PD-1-IN-1 is an inhibitor of programmed cell dealth-1 (PD-1). Synonyms: CA-170; CA-170; CA-170; AUPM 170; AUPM-170; AUPM170; PD-1-IN-1. (2S,3R)-2-[[(1S)-3-amino-1-[3-[(1R)-1-amino-2-hydroxyethyl]-1,2,4-oxadiazol-5-yl]-3-oxopropyl]carbamoylamino]-3-hydroxybutanoic acid; ZINC616580959. CAS No. 1673534-76-3. Molecular formula: C12H20N6O7. Mole weight: 360.32. | |
| PD-1-IN-17 | PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor. PD-1-IN-17 was first reported in patent WO2015033301A1, (Compound 12), inhibits 92% splenocyte proliferation at 100 nM. Synonyms: PD1-IN-1. CAS No. 1673560-66-1. Molecular formula: C13H22N6O7. Mole weight: 374.35. | |
| PD-1/PD-L1-IN-23 | PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester proagent of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597056-04-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145774. |  |
| PD-1/PD-L1 Inhibitor 1 | PD-1/PD-L1 Inhibitor 1, is an inhibitor of the PD-1 /PD-Ll protein/protein interaction. Synonyms: PD1-PDL1 inhibitor 1; PD1-PDL1-IN1; PD-1/PD-L1 inhibitor 1; PD-1/PD-L1 inhibitor 1; (2S) -1-[[2, 6-dimethoxy-4-[ (2-methyl-3-phenylphenyl) methoxy]phenyl]methyl]piperidine-2-carboxylic acidPD1-PDL1 inhibitor 1CHEMBL3582252(S)-1-(2,6-dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid1675201-83-8. CAS No. 1675201-83-8. Molecular formula: C29H33NO5. Mole weight: 475.58. | |
| PD-1/PD-L1 inhibitor 2 | The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM. Synonyms: BMS-202; BMS 202; BMS202. Grades: 98%. CAS No. 1675203-84-5. Molecular formula: C25H29N3O3. Mole weight: 419.52. | |
| PD-1/PD-L1 Inhibitor 3 | PD-1/PD-L1 Inhibitor 3 is a PD-1/PD-L1 interaction inhibitor with IC50 value of 5.6 nM. Synonyms: Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3. Grades: ≥97% by HPLC. CAS No. 1629654-95-0. Molecular formula: C89H126N24O18S. Mole weight: 1852.2. | |
| PD 224378 | PD 224378. Group: Biochemicals. Alternative Names: (4R)-1-(4-O- β-D-Galactopyranosyl- β-D-glucopyranosyl)-4-(2-methylpropyl)-2-pyrrolidinone. Grades: Highly Purified. CAS No. 501665-88-9. Pack Sizes: 1mg. Molecular Formula: C20H35NO11, Molecular Weight: 465.49. US Biological Life Sciences. | Worldwide |
| Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)) | Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)). CAS No: 51364-51-3 | Sarchem Laboratories New Jersey NJ |
| PD 312236, PD 312237 Mixture | PD 312236 is a pyranoside lactose conjugate degradation product of pregabalin, a GABA analogue used as an anticonvulsant. Group: Biochemicals. Alternative Names: 1-Deoxy-4-O- β-D-galactopyranosyl-1-[(4S)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]- β-D-fructose, Pyranose / Furanose Mixture. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??NO??, Molecular Weight: 465.49. US Biological Life Sciences. | Worldwide |
| PD 312237 | PD 312237. Group: Biochemicals. Alternative Names: 1-Deoxy-4-O- β-D-galactopyranosyl-1-[(4R)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]- β-D-fructofuranose. Grades: Highly Purified. CAS No. 501666-23-5. Pack Sizes: 1mg. Molecular Formula: C20H35NO11, Molecular Weight: 465.49. US Biological Life Sciences. | Worldwide |
| PD318088 | PD318088 is a MEK inhibitor. Synonyms: PD318088; PD 318088; PD-318088. CAS No. 391210-00-7. Molecular formula: C16H13BrF3IN2O4. Mole weight: 561.094. | |
| PD-321852 | PD-321852 is a small-molecule Chk1 inhibitor, which potentiates gemcitabine-induced clonogenic death in a panel of pancreatic cancer cell lines and evaluated the relationship between endpoints associated with Chk1 inhibition and chemosensitization. Gemcitabine chemosensitization by minimally toxic concentrations of PD-321852 ranged from minimal (<3-fold change in survival) in Panc1 cells to>30-fold in MiaPaCa2 cells. PD-321852 inhibited Chk1 in all cell lines as evidenced by stabilization of Cdc25A; in combination with gemcitabine, a synergistic loss of Chk1 protein was observed in the more sensitized cell lines. Synonyms: PD0321852; PD321852; 4-(2,6-dichlorophenyl)-9-hydroxy-6-(3-(methylamino)propyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione. Grades: 98%. CAS No. 622856-21-7. Molecular formula: C24H19Cl2N3O3. Mole weight: 468.33. | |
| PD-325901 3-Carboxylic Acid | PD-325901 3-Carboxylic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C16H12F3IN2O5, Molecular Weight: 496.18. US Biological Life Sciences. | Worldwide |
| PD-325901-d3 3-Caboxylic Acid | PD-325901-d3 3-Caboxylic Acid. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C16H9D3F3IN2O5, Molecular Weight: 499.2. US Biological Life Sciences. | Worldwide |
| PD-325901, Free Base (PD 0325901, MEK1/2 Inhibitor III) | A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC50 = 0.33nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells. PD 325901 is an inhibitor of mitogen activated protein kinase kinase (MEK or MAPKK). The potency, solubility and effectiveness of PD 325901 are greatly improved compared to PD 184352 (CI-1040). Group: Biochemicals. Alternative Names: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2[(2-fluoro-4-iodophenyl)amino]-benzamide; PD 0325901, MEK1/2 Inhibitor III. Grades: Highly Purified. CAS No. 391210-10-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| PD 334581 | PD 334581. Group: Biochemicals. Grades: Purified. CAS No. 548756-68-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 334581 | PD 334581, an analog of PD 184352, is an inhibitor of MEK1 that is used in biological studies to evaluate halogen bonding as a novel interaction for rational drug design. Synonyms: PD 334581; PD334581; PD-334581; N-[5-[3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl]-1,3,4-oxadiazol-2-yl]-4-morpholineethanamine. Grades: ≥98% by HPLC. CAS No. 548756-68-9. Molecular formula: C20H19F3IN5O2. Mole weight: 545.3. | |
| PD 404182 | PD 404182 is a high affinity inhibitor of KDO 8-P synthase (Ki = 26 nM), and also inhibits dimethylarginine dimethylaminohydrolase 1 (DDAH1). PD 404182 is a potential antibiotic of gram negative bacteria. Synonyms: PD-404182; PD 404182; PD404182. 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Grades: ≥98% by HPLC. CAS No. 72596-74-8. Molecular formula: C11H11N3S. Mole weight: 217.29. | |
| PD-407824 | PD-407824 is a Wee1/Chk1 inhibitor useful as cancer treatments. Group: Biochemicals. Alternative Names: 9-Hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione; PD 0407824. Grades: Highly Purified. CAS No. 622864-54-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 81723 | PD 81723. Group: Biochemicals. Grades: Purified. CAS No. 132861-87-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 81723 | PD 81723, an aminothiophene derivative, has been shown to act as an allosteric enhancer of the adenosine A1 receptor in brain membranes and thyroid cells, which acts via agonist-dependent and independent mechanisms. Synonyms: (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone; PD 81723; PD81723; NCGC00025124-01; CPD000468734; SAM001247067; PD-81,723; Methanone. Grades: ≥99% by HPLC. CAS No. 132861-87-1. Molecular formula: C14H12F3NOS. Mole weight: 299.31. | |
| PD 90780 | PD 90780, a pyrazoloquinazolinone compound, is a nonpeptide inhibitor of NGF binding to p75NTR (IC50 ~ 1 μM in CHO cells), which binds NGF, not p75NTR. Differential activity of PD90780 suggests altered NGF-p75NTR interactions in the presence of TrkA. It may be useful in identifying the region(s) of nerve growth factor involved in binding to the p75 receptor and in clarifying the role of p75 receptor in the actions of the neurotrophins. Synonyms: PD 90780; PD90780; PD-90780; 7-(Benzoylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid. Grades: ≥98% by HPLC. CAS No. 77422-99-2. Molecular formula: C19H14N4O4. Mole weight: 362.34. | |
| PD 90780 | PD 90780. Group: Biochemicals. Grades: Purified. CAS No. 77422-99-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD98059 | PD98059 is a potent, selective and cell-permeant inhibitor of MAP kinase kinase. It enhances human embryonic stem cell self-renewal. Synonyms: PD-98059; 2-(2-amino-3-methoxyphenyl)chromen-4-one. Grades: >98%. CAS No. 167869-21-8. Molecular formula: C16H13NO3. Mole weight: 267.284. | |
| PD 98059 | PD 98059. Group: Biochemicals. Grades: Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 98,059 | Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor. Blocks the phosphorylation and activation of the MAP kinase pathway. T cell activation inhibitor. Inhibits cell growth and cell proliferation of several cancer cells. Group: Biochemicals. Alternative Names: 2- (2-Amino-3-methoxyphenyl) -4H-1-benzopyran-4-one; 2- (2-amino-3-methoxyphenyl) oxanaphthalen-4-one; NSC 679828; PD 098059. Grades: Highly Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 5mg, 10mg, 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 267.3. US Biological Life Sciences. | Worldwide |
| pdAp | pdAp is a remarkable compound product, aiding in research for Parkinson's disease. Demonstrating its potent inhibitory capabilities, it skillfully suppresses the activity of the vital enzyme Dopa decarboxylase, thereby hindering the conversion of levodopa to dopamine. Synonyms: 2'- Deoxyadenosine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16174-58-6. Molecular formula: C10H15N5O9P2. Mole weight: 411.2. | |
| PDAT | PDAT is a noncompetitive indolethylamine-N-methyltransferase (INMT) inhibitor with a K i of 84 μM for rabbit lung INMT (rabINMT) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226213-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124101. | |
| pdBD-2 | pdBD-2 is an antimicrobial peptide found in Chinese loach, Paramisgurnus dabryanus. It has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Paramisgurnus dabryanus beta defensin 2. Grades: >98%. | |
| PDBT-co-TT | Flexible Printed Electronics. CAS No. 1260685-65-1. Catalog: ACM1260685651. | |
| PDBT-T1 | Band gap: 1.93 eV. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: Poly[[5,10-bis(5-octyl-2-thienyl)dithieno[2,3-d:2',3'-d']benzo[1,2-b:4,5-b']dithiophene-2,7-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c']dithiophene-1,3-diyl]-2,5-thiophenediyl]. CAS No. 1701403-91-9. Mole weight: (C72H78O2S10)n. |  |
| pdC-CE Phosphoramidite | pdC-CE Phosphoramidite is an essential reagent used in the synthesis of nucleic acids for biomedical research. Its high-quality and purity ensure efficient and reliable coupling during solid-phase oligonucleotide synthesis. This phosphoramidite is especially useful for the introduction of phosphodiester bonds in the presence of other modified nucleotides. Ideal for constructing therapeutic oligonucleotides targeting specific diseases. Synonyms: 5'-Dimethoxytrityl-N4-diisobutylaminomethylidene-5-(1-Propynyl)-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 193631-87-7. Molecular formula: C51H67N6O7P. Mole weight: 907.1. | |
| PDCD4-IN-1 | PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a K d value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 494763-64-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153383. | |
| PDCDT | PDCDT. Group: Organic field effect transistor (ofet) materials. Alternative Names: N N-BIS(2 5-DI-T-BU-PHENYL)-3 4 9 10-; N,N-bis(2,5-di-T-bu-phenyl)-3,4,9,10-perylenedic; N,N-bis(2,5-di-T-butylphenyl)-3,4*9,10-perylened; N,N-BIS(2,5-DI-T-BU-PHENYL)-3,4,9,10-PE RYLENEDICARBOXIMIDE; 2,9-BIS(2,5-BIS(1,1-DIMETHYLETHYL)PHENYL)-ANTRA(2,19-DEF:6. CAS No. 83054-80-2. Product ID: 7, 18-bis(2, 5-ditert-butylphenyl)-7, 18-diazaheptacyclo[14.6.2.22, 5.03, 12.04, 9.013, 23.020, 24]hexacosa-1(23), 2, 4, 9, 11, 13, 15, 20(24), 21, 25-decaene-6, 8, 17, 19-tetrone. Molecular formula: 767g/mol. Mole weight: C52H50N2O4. CC (C) (C)C1=CC (=C (C=C1)C (C) (C)C)N2C (=O)C3=C4C (=CC=C5C4=C (C=C3)C6=C7C5=CC=C8C7=C (C=C6)C (=O)N (C8=O)C9=C (C=CC (=C9)C (C) (C)C)C (C) (C)C)C2=O. InChI=1S/C52H50N2O4/c1-49 (2, 3)27-13-23-37 (51 (7, 8)9)39 (25-27)53-45 (55)33-19-15-29-31-17-21-35-44-36 (22-18-32 (42 (31)44)30-16-20-34 (46 (53)56)43 (33)41 (29)30)48 (58)54 (47 (35)57)40-26-28 (50 (4, 5)6)14-24-38 (40)52 (10, 11)12/h13-26H, 1-12H3. BIYPCKKQAHLMHG-UHFFFAOYSA-N. | |
| PdCl2(Amphos)2 | PdCl2(Amphos)2 is a catalyst that is more suitable for use in water than organic solvents [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 887919-35-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W010686. | |
| pdCp | The pdCp compound, renowned for its multifarious applications within the biomedical sector, epitomizes indispensability. Its predominant function involves serving as a seminal precursor in synthesizing pharmaceutical drugs, with a special focus on combatting cancer and inflammation-related illnesses. Imbued with the virtue of modulating intricate cellular pathways integral to disease progression, pdCp exhibits tremendous potential for therapeutic advancements. Synonyms: 2'- Deoxycytidine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 4682-43-3. Molecular formula: C9H15N3O10P2. Mole weight: 387.2. | |
| Pd(crotyl)qphoscl | Heterocyclic Organic Compound. CAS No. 1252598-33-6. Catalog: ACM1252598336. | |
| PDD 00017273 | PDD 00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor (IC50 = 26 nM), with >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3. PARG has been shown to be involved in the repair of single strand DNA breaks. PDD 00017273 (0.3 μM) also reduces the viability of BRCA1, BRCA2, PALB2, FAM175A, and BARD1 depleted cells. PDD 00017273 stalls replication forks and induces DNA damage that requires homologous recombination (HR) for repair. Synonyms: 1-[(1,3-Dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-dioxo-6-quinazolinesulfonamide. Grades: ≥98% by HPLC. CAS No. 1945950-21-9. Molecular formula: C23H26N6O4S2. Mole weight: 514.62. | |
| PDDC | PDDC is a compound used to inhibit Alzheimer's disease. It is a nSMase2 inhibitor that can inhibit tau-induced nSMase2 activity and ceramide elevation, and slow the spread of tau in mouse models. Uses: Scientific research. Group: Signaling pathways. CAS No. 2232878-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156800. | |
| PDDHV | PDDHV is a resiniferatoxin (RTX)-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat vanilloid receptor VR1 (TRPV1). It evoked 45Ca2+-uptake by rat dorsal root ganglion neurons in culture. Synonyms: Phorbol 12,13-didecanoate 20-homovanillate. Grades: ≥99%. CAS No. 179469-40-0. Molecular formula: C49H72O11. Mole weight: 837.1. | |
| PDE10A Inhibitor, Cpd15 (Phosphodiesterase 10A Inhibitor, (6-chloro-3,8-dimethyl-1H-pyrazolo[3,4-b]quinolin-4-yl)(2-methylpyrimidin-5-yl)methanol) | A cell-permeable pyrazoloquinoline compound that acts as a potent phosphodiesterase 10A inhibitor (Ki≤5nM against human PDE10A), while exhibiting >500-fold selectivity over other human PDEs 1-11 and little activity against CYP3A4 (IC50 >20uM) or a panel of 23 kinases (IC50 >30uM). Reported to be orally available in monkey and rat species and be efficacious in reversing nMDAR antagonist (+)-MK-801-induced hyperactivity in a ratsl (MED = 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. | Worldwide |
| PDE10-IN-1 is a potent PDE10-IN-1 inhibitor | Cas No. 1516896-09-5. | |
| PDE1B active from Rat, Recombinant | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene. Rat pde1b (genbank accession no. nm_022710) full length with n-terminal his-gst-tag, mw=89kda, expressed in a baculovirus infected sf9 cell expression system. Group: Enzymes. Synonyms: PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Purity: > 70% (SDS-PAGE). PDE. Mole weight: mol wt 89 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Cat No: NATE-0517. |  |
| PDE1-IN-1 | PDE1-IN-1 is a potent PDE1 inhibitor and neuroprotective agent. Synonyms: PDE1-IN-1. Grades: >98%. CAS No. 1160521-50-5. Molecular formula: C29H26FN7O. Mole weight: 507.56. | |
| PDE1-IN-2 | PDE1-IN-2 is an inhibitor of PDE1 that has IC50 values of 6, 140 and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. Synonyms: PDE1 IN 2; 6-bromo-7-(cyclopentylmethyl)-3-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]pyrazin-8-one. CAS No. 1904611-63-7. Molecular formula: C16H21BrN4O2. Mole weight: 381.27. | |
| PDE4A10 active from Human, Recombinant | Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW=117 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Uman pde4a10, also known as pde4a protein isoform 6, transcript variant 3 (genbank accession no. nm_001111309) amino acids 2-825 (end) with n-terminal gst-tag, mw=117 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 75% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 117 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0523. | |
| PDE4A4B active from Human, Recombinant | Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4a4b, also known as pde4a isoform 1 (genbank accession no. nm_001111307) amino acids 2-end with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 40% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0524. | |
| PDE4D2 active from Human, Recombinant | Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d2 (genbank accession no. nm_001197221) amino acids 2-507 (end) with n-terminal gst-tag, mw=84 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 80% (SDS-PAGE). PDE. Mole weight: mol wt 84 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0525. | |
| PDE4D7 active from Human, Recombinant | Human PDE4D7 (GenBank Accession No. NM_001165899) amino acids 2-748 (end) with N-terminal GST-tag, MW=111 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d7 (genbank accession no. nm_001165899) amino acids 2-748 (end) with n-terminal gst-tag, mw=111 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 111 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0526. | |
| PDE4D Inhibitor, GEBR-7b ((E)-3-(cyclopentyloxy)-4-methoxybenzaldehyde, O-2-(2,6-dimethylmorpholino)-2-oxoethyl oxime, GEBR-7b) | A cell permeable, potent, and selective oxime PDE4D inhibitor (IC50=0.67uM) which displays much reduced activities toward other PDE4 isoforms. It is shown to cause a significant 40% increase in extracellular cAMP in the hippocampus of freely moving rats in vivo at 100uM, but has no effect on Ab levels. This compound elicits cognitive enhancement in vivo at the optimum dose of 0.003mg/kg in both mice and rat models, and unlike rolipram, does not cause emesis-like behavior in rodents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PDE5A1 active from Mouse, Recombinant | Mouse PDE5A (GenBank Accession No. NM_153422) full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Mouse pde5a (genbank accession no. nm_153422) full length with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Purity: > 70% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Cat No: NATE-0528. | |
| PDE5 inhibitor 42 | PDE5 inhibitor 42 is a second-generation phosphodiesterase type 5 (PDE5) inhibitor (IC50 = 0.04 nM). Synonyms: PDE5 Inhibitor 42; PDE5-Inhibitor-42; PDE5Inhibitor42; PDE5-IN-42; PDE5 IN 42; PDE5IN42; 1-[1-(2-Ethoxyethyl)-3-ethyl-7-[(4-methylpyridin-2-yl)amino]pyrazolo[4,3-d]pyrimidin-5-yl]piperidine-4-carboxylic acid. Grades: 98%. CAS No. 936449-28-4. Molecular formula: C23H31N7O3. Mole weight: 453.54. | |
| PDE-5 Inhibitor (Sildenafil Related Compound) | Cas No. 1393816-99-3. | |
| PDE7B active from Mouse, Recombinant | Mouse PDE7B (GenBank Accession No. NM_013875) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Mouse pde7b (genbank accession no. nm_013875) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0531. | |
| PDE7B active from Rat, Recombinant | Rat PDE7B (GenBank Accession No. NM_080894) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Rat pde7b (genbank accession no. nm_080894) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 30% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0532. | |
| PDE-9 inhibitor | PDE-9 inhibitor is useful for neurodegenerative diseases. Synonyms: PDE 9 inhibitor; PDE9 inhibitor; PDE-9 inhibitor. Grades: >98%. CAS No. 1082743-70-1. Molecular formula: C22H27N5O2. Mole weight: 393.48. | |
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