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| Product | Description | |
|---|---|---|
| PD 161570 | PD 161570. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H35Cl2N7O. US Biological Life Sciences. |  Worldwide |
| PD-161570 | A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PD 166285 | PD 166285. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -2-[[4-[2- (diethylamino) ethoxy]phenyl]amino]-8-methylpyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 212391-63-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H29Cl4N5O2. US Biological Life Sciences. | Worldwide |
| PD 166793 | PD 166793. Group: Biochemicals. Alternative Names: PD 166793-0000; N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-Valine. Grades: Highly Purified. CAS No. 199850-67-4. Pack Sizes: 10mg. Molecular Formula: C17H18BrNO4S, Molecular Weight: 412.3. US Biological Life Sciences. | Worldwide |
| PD166866 | PD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD166866 has clear antiproliferative effects. Uses: Protein kinase inhibitors. Alternative Names: PD166866; PD-166866; PD 166866. Grades: 98%. CAS No. 192705-79-6. Molecular formula: C20H24N6O3. Mole weight: 396.45. |  |
| PD 166866 | PD 166866. Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl). Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H24N6O3. US Biological Life Sciences. | Worldwide |
| PD-166866 | A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF). Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl). Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PD-166866 | PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC50 of 52.4 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 192705-79-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101296. |  |
| PD 168077 maleate | PD 168077 maleate. Group: Biochemicals. Grades: Purified. CAS No. 630117-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 168077 Maleate (D4 Dopamine Receptor Agonist, PD 168077 Maleate, PD168077, PD-168077) | A selective D4 dopamine receptor agonist (Ki = 8.7nM, EC50 = 8.3nM). Suitable for central and peripheral delivery. Used in studies of penile erection, learning and memory. Exibits some binding affinity towards human D2 and D3 Receptors (Ki = 2.8uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 630117-19-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 168368 | PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15-45 nM[1]. PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist[2]. PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 204066-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116216. | |
| PD168393 | PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 194423-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13896. | |
| PD 168568 dihydrochloride | PD 168568 dihydrochloride is a orally active and potent dopamine receptor D4 (DRD4) antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for the D4 receptor versus D2 and D3, with Ki values of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1782532-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103407A. | |
| PD 168568 dihydrochloride | PD 168568 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 210688-56-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 169316 | PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71. Uses: Scientific research. Category: Signaling pathways. CAS No. 152121-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10578. | |
| PD173074 | PD173074 is a potent FGFR1 inhibitor with an IC50 of 25 nM and also inhibits VEGFR2 with an IC50 of 100-200 nM, showing 1000-fold selectivity for FGFR1 over PDGFR and c-Src. Uses: Scientific research. Category: Signaling pathways. CAS No. 219580-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10321. | |
| PD173074 | PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a therapeutic modality using eight UC cell lines. PD173074 suppressed cell proliferation remarkably in two cell lines, namely, UM-UC-14 and MGHU3, which expressed mutated FGFR3 protein. Cell cycle analysis revealed the growth inhibitory effect of PD173074 was associated with arrest at G(1)-S transition in a dose-depending manner. In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3, orally administered PD173074 suppressed tumor growth and induced apoptotic changes comparable with the results of our in vitro assay. These findings elucidated the effectiveness of molecular targeted approach for bladder UC harboring FGFR3 mutations and the potential utility to decrease the intravesical recurrence of nonmuscle invasive bladder UC after transurethral surgical resection. Uses: Differentiation, self-renewal. Alternative Names: PD173074; PD 173074; PD-173074. Grades: 0.98. CAS No. 219580-11-7. Molecular formula: C28H41N7O3. Mole weight: 523.682. | |
| PD173074 | PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells. Group: Inhibitors. CAS No. 219580-11-7. Pack Sizes: 5mg. Product ID: S1264. Formula: C28H41N7O3. Smiles: CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor) | PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor). Group: Biochemicals. Alternative Names: 1-tert-butyl-3-[2-[4- (diethylamino) butylamino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 25mg. Molecular Formula: C28 H41 N7O3 , Molecular Weight: 523.7. US Biological Life Sciences. | Worldwide |
| PD173212 | PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays. Uses: Scientific research. Category: Signaling pathways. CAS No. 217171-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103318. | |
| PD 173212 | PD 173212. Group: Biochemicals. Grades: Purified. CAS No. 217171-01-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD173952 | PD173952 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively. PD173952 is also a potent Myt1 kinase inhibitor with a Ki of 8.1 nM. PD173952 induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 305820-75-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122113. | |
| PD 173952 | PD 173952. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -8-methyl-2-[[4- (4-morpholinyl) phenyl]amino]pyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 305820-75-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H21Cl2N5O2. US Biological Life Sciences. | Worldwide |
| PD173955 | PD173955 is an orally active inhibitor of Src (IC50= 22 nM), Yes, Abl, ATP and MAP kinases. PD173955 can effectively prevent the mitotic process and has anticancer activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 260415-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10395. | |
| PD-173955 | PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth. Alternative Names: PD173955; PD 173955; PD-173955. Grades: 0.98. CAS No. 260415-63-2. Molecular formula: C21H16Cl2N4OS. Mole weight: 443.35. | |
| PD 174265 | PD 174265 is a highly selective, reversible EGFR/ErbB2 tyrosine kinase inhibitor (IC50=0.45 nM) and cell differentiation inducer. By blocking receptor autophosphorylation and the downstream ERK signaling pathway (with an IC50 of 0.45 μM for full-length ERK), PD 174265 effectively inhibits tumor growth and exhibits antitumor activity without obvious toxicity in in vivo models. PD 174265 drives oligodendrocyte precursor cells to switch from a proliferative state to a differentiated state, significantly upregulates the expression of myelin proteins such as CNP, PLP and MBP, and induces neurite branching. PD 174265 shows no inhibitory effect on other kinases including insulin, PDGF and basic FGF receptors, and serves as a crucial tool molecule for investigating the treatment of human epidermoid carcinoma and the mechanism of myelin repair in multiple sclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 216163-53-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112411. | |
| PD176252 | PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 204067-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103286. | |
| PD 176252 | PD 176252. CAS No: 204067-01-6 |  Sarchem Laboratories New Jersey NJ |
| PD 176252 | PD 176252. Group: Biochemicals. Grades: Purified. CAS No. 204067-01-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD180970 | PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287204-45-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103274. | |
| PD 184161 | PD 184161. Group: Biochemicals. Alternative Names: 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-67-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H13BrClF2IN2O2. US Biological Life Sciences. | Worldwide |
| PD 184352 | PD 184352. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14ClF2IN2O2. US Biological Life Sciences. | Worldwide |
| PD 198306 | PD 198306. Group: Biochemicals. Grades: Purified. CAS No. 212631-61-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 198306 | PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 212631-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107620. | |
| PD-1-IN-17 | PD-1-IN-17 is a programmed cell death-1 (PD-1) inhibitor. PD-1-IN-17 was first reported in patent WO2015033301A1, (Compound 12), inhibits 92% splenocyte proliferation at 100 nM. Alternative Names: PD1-IN-1. CAS No. 1673560-66-1. Molecular formula: C13H22N6O7. Mole weight: 374.35. | |
| PD-1 (Intracellular Domain) Antibody [G6H24] | PD-1 (Intracellular Domain) Antibody [G6H24]. Group: Antibodies. Alternative Names: Programmed cell death protein 1, Protein PD-1, Pdcd1, Pd1. Pack Sizes: 20uL. Product ID: F3016. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| PD-1/PD-L1-IN-23 | PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice. CAS No. 2597056-04-5. Molecular formula: C32H30BrCl2N3O6. Mole weight: 703.41. | |
| PD-1/PD-L1-IN-29 | PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2665734-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152240. | |
| PD-1/PD-L1-IN-9 | PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 also exhibits significant in vivo antitumor activity in a CT26 mouse model. Grades: 98%. CAS No. 2628506-54-5. Molecular formula: C22H24N2O2. Mole weight: 348.44. | |
| PD-1/PD-L1 inhibitor 2 | The programmed death-1 / programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM. Alternative Names: BMS-202; BMS 202; BMS202. Grades: 98%. CAS No. 1675203-84-5. Molecular formula: C25H29N3O3. Mole weight: 419.52. | |
| PD-1/PD-L1 Inhibitor 3 | PD-1/PD-L1 Inhibitor 3 is a PD-1/PD-L1 interaction inhibitor with IC50 value of 5.6 nM. Alternative Names: Programmed Death-1 / Programmed Death-Ligand 1 Inhibitor 3. Grades: ≥97% by HPLC. CAS No. 1629654-95-0. Molecular formula: C89H126N24O18S. Mole weight: 1852.2. | |
| Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)) | Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)). CAS No: 51364-51-3 | Sarchem Laboratories New Jersey NJ |
| PD318088 | PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352 (HY-50295). PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 391210-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12062. | |
| PD 334581 | PD 334581. Group: Biochemicals. Grades: Purified. CAS No. 548756-68-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 404182 | PD 404182. Alternative Names: 3,4-Dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. CAS No. 72596-74-8. Product ID: ACM72596748-1. Molecular formula: C11H11N3S. Mole weight: 217.29. IUPAC Name: 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Canonical SMILES: C1CN=C2C3=CC=CC=C3SC(=N)N2C1. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| PD 407824 | PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC50s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 622864-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18961. | |
| PD 81723 | PD 81723. Group: Biochemicals. Grades: Purified. CAS No. 132861-87-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 90780 | PD 90780. Group: Biochemicals. Grades: Purified. CAS No. 77422-99-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 90780 | PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77422-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110166. | |
| PD98059 | PD98059 is a potent, selective and cell-permeant inhibitor of MAP kinase kinase. It enhances human embryonic stem cell self-renewal. Alternative Names: PD-98059; 2-(2-amino-3-methoxyphenyl)chromen-4-one. Grades: >98%. CAS No. 167869-21-8. Molecular formula: C16H13NO3. Mole weight: 267.284. | |
| PD98059 | PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 μM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 μM) and MEK2 (IC50 of 50 μM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 167869-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12028. | |
| PD 98059 | PD 98059. Group: Biochemicals. Grades: Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 98059 | PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist. Group: Inhibitors. CAS No. 167869-21-8. Pack Sizes: 10mg. Product ID: S1177. Formula: C16H13NO3. Smiles: COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| pdAp | pdAp is a remarkable compound product, aiding in research for Parkinson's disease. Demonstrating its potent inhibitory capabilities, it skillfully suppresses the activity of the vital enzyme Dopa decarboxylase, thereby hindering the conversion of levodopa to dopamine. Alternative Names: 2'- Deoxyadenosine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16174-58-6. Molecular formula: C10H15N5O9P2. Mole weight: 411.2. | |
| pdBD-2 | pdBD-2 is an antimicrobial peptide found in Chinese loach, Paramisgurnus dabryanus. It has anti-gram-positive bacteria and gram-negative bacteria activity. Alternative Names: Paramisgurnus dabryanus beta defensin 2. Grades: >98%. | |
| PDBPyBT | PDBPyBT. Alternative Names: Poly(2,5-bis(2-octyldodecyl)-3,6-di(pyridin-2-yl)-pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione-alt-2,2'-bithiophene), PDBPyBT, DPP-DPyBT. CAS No. 1455028-36-0. Molecular formula: (C64H92N4O2S2)n. | |
| PDBT-T1 | Band gap: 1.93 eV. Alternative Names: Poly[[5,10-bis(5-octyl-2-thienyl)dithieno[2,3-d:2',3'-d']benzo[1,2-b:4,5-b']dithiophene-2,7-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c']dithiophene-1,3-diyl]-2,5-thiophenediyl]. CAS No. 1701403-91-9. Molecular formula: (C72H78O2S10)n. |  |
| PDC31 | PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca2+-dependent large-conductance K+-channel in human myometrial cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: THG113.31; ILGHXDYK. CAS No. 634586-40-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4160. | |
| pdC-CE Phosphoramidite | pdC-CE Phosphoramidite is an essential reagent used in the synthesis of nucleic acids for biomedical research. Its high-quality and purity ensure efficient and reliable coupling during solid-phase oligonucleotide synthesis. This phosphoramidite is especially useful for the introduction of phosphodiester bonds in the presence of other modified nucleotides. Ideal for constructing therapeutic oligonucleotides targeting specific diseases. Alternative Names: 5'-Dimethoxytrityl-N4-diisobutylaminomethylidene-5-(1-Propynyl)-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 193631-87-7. Molecular formula: C51H67N6O7P. Mole weight: 907.1. | |
| PDCDT | PDCDT. Alternative Names: N N-BIS(2 5-DI-T-BU-PHENYL)-3 4 9 10-;N,N-bis(2,5-di-T-bu-phenyl)-3,4,9,10-perylenedic;N,N-bis(2,5-di-T-butylphenyl)-3,4*9,10-perylened;N,N-BIS(2,5-DI-T-BU-PHENYL)-3,4,9,10-PE RYLENEDICARBOXIMIDE;2,9-BIS(2,5-BIS(1,1-DIMETHYLETHYL)PHENYL)-ANTRA(2,19-DEF:6. CAS No. 83054-80-2. Molecular formula: C52H50N2O4. Mole weight: 767g/mol. IUPAC Name: 7,18-bis(2,5-ditert-butylphenyl)-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone. SMILES: CC(C)(C)C1=CC(=C(C=C1)C(C)(C)C)N2C(=O)C3=C4C(=CC=C5C4=C(C=C3)C6=C7C5=CC=C8C7=C(C=C6)C(=O)N(C8=O)C9=C(C=CC(=C9)C(C)(C)C)C(C)(C)C)C2=O. InChI: InChI=1S/C52H50N2O4/c1-49(2,3)27-13-23-37(51(7,8)9)39(25-27)53-45(55)33-19-15-29-31-17-21-35-44-36(22-18-32(42(31)44)30-16-20-34(46(53)56)43(33)41(29)30)48(58)54(47(35)57)40-26-28(50(4,5)6)14-24-38(40)52(10,11)12/h13-26H,1-12H3. | |
| PdCl2(Amphos)2 | PdCl2(Amphos)2 is a highly efficient palladium catalyst. PdCl2(Amphos)2 can be used in research related to organic synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 887919-35-9. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-W010686. | |
| pdCp | The pdCp compound, renowned for its multifarious applications within the biomedical sector, epitomizes indispensability. Its predominant function involves serving as a seminal precursor in synthesizing pharmaceutical drugs, with a special focus on combatting cancer and inflammation-related illnesses. Imbued with the virtue of modulating intricate cellular pathways integral to disease progression, pdCp exhibits tremendous potential for therapeutic advancements. Alternative Names: 2'- Deoxycytidine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 4682-43-3. Molecular formula: C9H15N3O10P2. Mole weight: 387.2. | |
| PDD00017272 | PDD00017272 is an inhibitor of poly(ADP-ribose) glycohydrolase (PARG) (EC50=4.8 nM) and an activator of PARP1/2. PDD00017272 inhibits its activity of hydrolyzing poly(ADP-ribose) (pADPr), resulting in the accumulation of pADPr on chromatin, interfering with DNA damage repair and replication processes, and inducing PARP1/2-dependent cytotoxicity. PDD00017272 can be used in cancer models with DNA repair defects (such as BRCA mutations) or resistance to PARP inhibitors. PDD00017272 has a PARG expression level-correlated inhibitory potency with EC50 of 9.2 nM (PARG cells), the tumor cells with lower PARG expression are more sensitive[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945950-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133531. | |
| PDD00017273 | PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50 of 26 nM. PDD00017273 exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3. Group: Inhibitors. CAS No. 1945950-21-9. Pack Sizes: 5mg. Product ID: S8862. Formula: C23H26N6O4S2. Smiles: CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C)C. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| PDD 00017273 | PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945950-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108360. | |
| PDE10-IN-5 | PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 898562-99-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14550A. | |
| PDE12-IN-1 | PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2,5-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259620-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117318. | |
| PDE1B active from Rat, Recombinant | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene. Rat pde1b (genbank accession no. nm_022710) full length with n-terminal his-gst-tag, mw=89kda, expressed in a baculovirus infected sf9 cell expression system. Group: Enzymes. Synonyms: PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Purity: > 70% (SDS-PAGE). PDE. Mole weight: mol wt 89 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Cat No: NATE-0517. |  |
| PDE4A10 active from Human, Recombinant | Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW=117 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Uman pde4a10, also known as pde4a protein isoform 6, transcript variant 3 (genbank accession no. nm_001111309) amino acids 2-825 (end) with n-terminal gst-tag, mw=117 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 75% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 117 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0523. | |
| PDE4A4B active from Human, Recombinant | Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4a4b, also known as pde4a isoform 1 (genbank accession no. nm_001111307) amino acids 2-end with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 40% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0524. | |
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