A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Palbociclib Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. Group: Inhibitors. Alternative Names: PD0332991 Isethionate. CAS No. 827022-33-3. Pack Sizes: 50mg. Product ID: S1579. Formula: C24H29N7O2.C2H6O4S. Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Pd-100
Pd-100. Tyger suppliers of organic specialty chemicals & custom chemical synthesis.
PD 102807
PD 102807 is a M4 muscarinic receptor antagonist with an IC 50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC 50 s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively [1]. Antidyskinetic effect. Uses: Scientific research. Group: Signaling pathways. CAS No. 23062-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107646.
PD 102807
PD 102807. Group: Biochemicals. Grades: Purified. CAS No. 23062-91-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD-116152
PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp. Uses: Pd-116152 has antitumor activity. Synonyms: PD-116,152; PD116,152; PD 116,152; PD116152; PD 116152; 6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester; Methyl 6-formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylate. Grade: >98 %. CAS No. 101708-64-9. Molecular formula: C16H12N2O6. Mole weight: 328.28.
PD-116779
PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class. Uses: Pd-116779 is a novle antitumor antibiotic. Synonyms: PD116,779; PD 116,779; PD-116,779; PD116779; PD 116779; 3,4-Dihydro-2,3,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; 2,3,8-Trihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. Grade: >98 %. CAS No. 102674-89-5. Molecular formula: C19H14O6. Mole weight: 338.31.
PD 118057
PD 118057. Group: Biochemicals. Grades: Purified. CAS No. 313674-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
PD-118576 is an antitumor macrolide antibiotic produced by Streptomyces sp. WP 3913. It exhibits moderate activity against bacteria and fungi. Synonyms: PD 118576; PD118576; PD-118,576; PD 118,576; PD118,576. CAS No. 100632-37-9. Molecular formula: C33H52O8. Mole weight: 576.8.
PD-123319 Bis(trifluoroacetate) Salt Hydrate
A selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells. Group: Biochemicals. Alternative Names: (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319 Bis(trifluoroacetate) Salt Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PD 123319 ditrifluoroacetate
PD 123319 ditrifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 130663-39-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 123319 ditrifluoroacetate
PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC 50 of 34 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 136676-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10259A.
PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 ?M). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI 976. CAS No. 114289-47-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107572.
PD 128907 hydrochloride
PD 128907 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 112960-16-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100539A.
PD 135158
PD 135158. Group: Biochemicals. Grades: Purified. CAS No. 130285-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 144418-d7 Oxalate
PD 144418-d7 Oxalate. Group: Biochemicals. Alternative Names: 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine-d7 Oxalate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H17D7N2O5, Molecular Weight: 379.46. US Biological Life Sciences.
Worldwide
PD 145065 - CAS 153049-49-1
A highly potent but non-selective endothelin receptor antagonist [IC??= 4 nM for the ETA receptor (rabbit renal artery vascular smooth muscle cells); IC?? = 15 nM for the ETB receptor (rat cerebellum)]. Group: Fluorescence/luminescence spectroscopy.
PD 146176
PD 146176. Group: Biochemicals. Grades: Purified. CAS No. 4079-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with K i values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179528-45-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100529.
PD 150606
PD 150606. Group: Biochemicals. Alternative Names: (2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid; (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid. Grades: Highly Purified. CAS No. 179528-45-1. Pack Sizes: 10mg. Molecular Formula: C9H7IO2S, Molecular Weight: 306.12. US Biological Life Sciences.
A cell-permeable, non-peptidic, and highly selective calpain inhibitor directed towards the calcium binding sites of calpain. Group: Fluorescence/luminescence spectroscopy.
PD153035
PD153035 (SU-5271; AG1517; ZM 252868) is a potent EGFR inhibitor with K i and IC 50 of 6 and 25 pM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU-5271; AG1517; ZM 252868. CAS No. 153436-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14346.
PD 153035 - CAS 153436-54-5
An extremely potent, cell-permeamble, reversible, ATP-competitive and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC?? = 25 pM; Ki = 6 pM). Group: Fluorescence/luminescence spectroscopy.
PD153035 Hydrochloride (SU-5271 Hydrochloride) is a potent EGFR inhibitor with K i and IC 50 of 6 and 25 pM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU-5271 Hydrochloride; AG1517 Hydrochloride; ZM 252868 Hydrochloride. CAS No. 183322-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12013.
PD-156707
PD-156707 is an orally active, nonpeptide and selective Endothelin-A receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162412-70-6. Pack Sizes: 5 mg. Product ID: HY-123744.
PD 158780. Group: Biochemicals. Grades: Purified. CAS No. 171179-06-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 158780 - CAS 171179-06-9
A potent, cell-permeable, reversible, ATP-competitive inhibitor of the EGFR tyrosine kinase activity (IC?? = 8 pM). Group: Fluorescence/luminescence spectroscopy.
PD159206
PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HIV. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PD-159206; PD159206; PD 159206; CI 1013; CI-1013; CI1013; DIBA 4. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 171744-42-6. Molecular formula: C26H32N2O6S2. Mole weight: 532.67. Purity: >95%. IUPACName: N,N'-[Dithiobis(2,1-phenylenecarbonyl)]bis[isoleucine]. Canonical SMILES: O=C(N[C@@H]([C@@H](C)CC)C(O)=O)C1=CC=CC=C1SSC2=CC=CC=C2C(N[C@@H]([C@@H](C)CC)C(O)=O)=O. Product ID: ACM171744426. Alfa Chemistry ISO 9001:2015 Certified. Categories: DIBA-4 ENANTIOMER.
PD 160170
PD 160170. Group: Biochemicals. Grades: Purified. CAS No. 181468-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD-160725 2-Hydroxyethanesulfonate
PD-160725 2-Hydroxyethane sulfonate. Group: Biochemicals. Alternative Names: 2-Hydroxyethanesulfonic Acid 1,4-Dihydro-6-methyl-7-nitro-5-(1-piperidinylmethyl)-2,3-quinoxalinedione; PD-160725 Isethionate Salt. Grades: Highly Purified. CAS No. 1262769-92-5. Pack Sizes: 10mg. Molecular Formula: C17H24N4O8S, Molecular Weight: 444.46. US Biological Life Sciences.
Worldwide
PD 161570
PD 161570. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H35Cl2N7O. US Biological Life Sciences.
Worldwide
PD-161570
A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 5mg. US Biological Life Sciences.
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC50s of 450 nM and 622 nM, respectively[1][2]. PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-? signaling inhibitor[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192705-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100434.
PD-161989 2-Hydroxyethane sulfonate. Group: Biochemicals. Alternative Names: 2-Hydroxyethanesulfonic Acid 1,4-Dihydro-6-methyl-7-nitro-5-(1-pyrrolidinylmethyl)-2,3-quinoxalinedione. Grades: Highly Purified. CAS No. 1262770-05-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PD 166285
PD 166285. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -2-[[4-[2- (diethylamino) ethoxy]phenyl]amino]-8-methylpyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 212391-63-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H29Cl4N5O2. US Biological Life Sciences.
Worldwide
PD-166285
A broad-spectrum receptor tyrosine kinase (RTK) inhibitor. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -2-[[4-[2- (diethylamino) ethoxy]phenyl]amino]-8-methylpyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 212391-63-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PD 166285 - CAS 212391-63-4
A cell-permeable, orally bioavailable, ATP-competitive, broad-spectrum tyrosine kinase inhibitor that suppresses angiogenesis both in vitro and in vivo. Group: Fluorescence/luminescence spectroscopy.
PD-166285-d4
A labeled broad-spectrum receptor tyrosine kinase (RTK) inhibitor. Group: Biochemicals. Alternative Names: 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy-d4]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
PD 166866. Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) . Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H24N6O3. US Biological Life Sciences.
Worldwide
PD-166866
PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC 50 of 52.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 192705-79-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101296.
PD-166866
A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF). Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) . Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 5mg. US Biological Life Sciences.
PD 168077 maleate. Group: Biochemicals. Grades: Purified. CAS No. 630117-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD-168077 maleate
PD-168077 maleate is a selective dopamine D 4 receptor agonist, with a K i of 9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 630117-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-21098A.
A selective D4 dopamine receptor agonist (Ki = 8.7nM, EC50 = 8.3nM). Suitable for central and peripheral delivery. Used in studies of penile erection, learning and memory. Exibits some binding affinity towards human D2 and D3 Receptors (Ki = 2.8uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 630117-19-0. Pack Sizes: 10mg. US Biological Life Sciences.