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| Product | Description | |
|---|---|---|
| p-Cresol-[d3] | p-Cresol-[d3]. Synonyms: p-Cresol-D3 (methyl-D3); 4-(Methyl-d3)-phenol. Grade: 98% atom D. CAS No. 108561-00-8. Molecular formula: C7H5D3O. Mole weight: 111.16. |  |
| p-Cresol-[d5] | p-Cresol-[d5]. Synonyms: p-Cresol-2,3,5,6-d4,OD. Grade: 98% atom D. CAS No. 3646-98-8. Molecular formula: C7H3D5O. Mole weight: 113.17. | |
| p-Cresol-d7 | This compound is the labelled analog of a cresol metabolite. Group: Biochemicals. Alternative Names: 4-Methylphenol-d7; 4-(Methyl-d3)-phen-2,3,5,6-d4-ol. Grades: Highly Purified. CAS No. 202325-52-8. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C7HD7O. US Biological Life Sciences. |  Worldwide |
| p-Cresol-[d7] | p-Cresol-[d7]. Synonyms: p-Cresol D7; 4-Methylphenol-d7; 4-(Methyl-d3)-phen-2,3,5,6-d4-ol. Grade: 98% atom D. CAS No. 202325-52-8. Molecular formula: C7HD7O. Mole weight: 115.18. | |
| p-Cresol-[d8] | P-Cresol-[d8] is the labelled form of p-Cresol. p-Cresol is used in the synthesis of Bupranolol, a non-selective beta blocker. Synonyms: 4-Methylphenol-d8; 4-(Methyl-d3)phen-2,3,5,6-d4-ol-d. Grade: ≥98% by CP; ≥98% atom D. CAS No. 190780-66-6. Molecular formula: C7D8O. Mole weight: 116.19. | |
| p-Cresol glucuronide | p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 17680-99-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W416250. |  |
| p-Cresol Glucuronide | p-Cresol Glucuronide. Group: Biochemicals. Alternative Names: 4-Methylphenyl β-D-Glucopyranosiduronic Acid; β-D-p-Tolyl-glucopyranosiduronic Acid; p-Tolyl- β-D-glucosiduronic Acid; 4-Cresol Glucuronide; p-Methylphenyl- β-D-glucopyranosiduronic Acid; p-Tolyl- β-glucuronic Acid. Grades: Highly Purified. CAS No. 17680-99-8. Pack Sizes: 10mg. Molecular Formula: C13H16O7, Molecular Weight: 284.26. US Biological Life Sciences. | Worldwide |
| p-Cresol Glucuronide-d7 | p-Cresol Glucuronide-d7. Group: Biochemicals. Alternative Names: 4-Methylphenyl β-D-Glucopyranosiduronic Acid-d7; β-D-p-Tolyl-glucopyranosiduronic Acid;-d7 p-Tolyl- β-D-glucosiduronic Acid-d7; 4-Cresol Glucuronide-d7; p-Methylphenyl- β-D-glucopyranosiduronic Acid-d7; p-Tolyl- β-glucuronic Acid-d7. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C13H9D7O7, Molecular Weight: 291.31. US Biological Life Sciences. | Worldwide |
| p-Cresol, High Purity | P-cresol is a colorless solid with a tar like odor. Sinks and mixes slowly with water. (USCG, 1999);Liquid; PelletsLargeCrystals;Solid;Solid;COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR AND LIGHT.;Colourless to pink crystals, tarry-smoky medicinal odour;White crystals with a sweet, tarry odor.;Crystalline solid with a sweet, tarry odor. [Note: A liquid above 95°F.]. CAS No. 106-44-5. Molecular formula: C7H8O;CH3C6H4OH;C7H8O. Mole weight: 108.14g/mol. IUPAC Name: 4-methylphenol. SMILES: CC1=CC=C(C=C1)O. InChI: InChI=1S/C7H8O/c1-6-2-4-7(8)5-3-6/h2-5,8H,1H3. |  |
| p-Cresol-[methyl-13C] | P-Cresol-[methyl-13C] is the labelled form of p-Cresol. p-Cresol is used in the synthesis of Bupranolol, a non-selective beta blocker. Synonyms: 4-Methyl-13C-phenol; p-Cresol-α-13C; Phenol-4-(methyl-13C). Grade: 99% by CP; 99% atom 13C. CAS No. 121474-53-1. Molecular formula: C6[13C]H8O. Mole weight: 109.13. | |
| p-Cresol sulfate-d7 potassium | p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate-d7 potassium. CAS No. 2469278-96-2. Pack Sizes: 5 mg. Product ID: HY-111431AS. | |
| p-Cresyl sulfate | p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate. CAS No. 3233-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-111431. | |
| p-Cresyl sulfate potassium | p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate potassium. CAS No. 91978-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg. Product ID: HY-111431A. | |
| p-Cresyl sulfate potassium (Standard) | p-Cresyl sulfate (potassium) (Standard) is the analytical standard of p-Cresyl sulfate (potassium). This product is intended for research and analytical applications. p-Cresyl sulfate (p-Tolyl sulfate) potassium is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate potassium shows antiproliferation activity. p-Cresyl sulfate potassium increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate potassium induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate potassium (Standard). CAS No. 91978-69-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111431AR. | |
| PCR Stimulant | PCR Stimulant. Pcr stimulant can be used to increase sensitivity and specificity for gc/at-rich template or complex template. it is especially suitable for pfu enzymes. the stock concentration is 5×, and the working concentration can be varied between 0.5× to 2.5×. Group: Cloning Enzymes. Purity: 200ul. Storage: Store at -20 ?. Cat No: CE-3010. |  |
| PCSK9-IN-29 | PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1233353-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159595. | |
| PCTFE Products | PCTFE Products. | |
| Pct I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme >90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GAATGCN↑ CTTAC↓GN. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Planococcus citreus SM. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; and 50% glycerol. Cat No: ET-1147RE. | |
| p-Cumenesulphonic acid | p-Cumenesulphonic acid. Alternative Names: p-cumenesulphonic acid;4-Cumenesulfonic acid. CAS No. 16066-35-6. Product ID: ACM16066356. Molecular formula: C9H12O3S. Mole weight: 200.25478. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| p-Cyanobenzylidene p-Nonyloxyaniline | CBNOA or CN.9, liquid crystal. CAS No. 67363-89-7. Pack Sizes: Typically in stock: 1g. Mole weight: 348.49. MP/BP: M.P. 71 (S), 99 (N), 105 (I). Order No: FR-0486. |  Frinton Laboratories |
| PD0166285 | PD0166285, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 exhibits an IC50 of 3.433 μM for Chk1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 185039-89-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13925. | |
| PD0325901 (Mirdametinib) | Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2. Group: Inhibitors. CAS No. 391210-10-9. Pack Sizes: 5mg. Product ID: S1036. Formula: C16H14F3IN2O4. Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| PD-0332991 (Palbociclib) Hydrochloride | Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. Group: Inhibitors. CAS No. 827022-32-2. Pack Sizes: 5mg. Product ID: S1116. Formula: C24H29N7O2.HCl. Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| PD-0332991 (Palbociclib) Isethionate | Palbociclib Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. Group: Inhibitors. Alternative Names: PD0332991 Isethionate. CAS No. 827022-33-3. Pack Sizes: 50mg. Product ID: S1579. Formula: C24H29N7O2.C2H6O4S. Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| PD 102807 | PD 102807 is a M4 muscarinic receptor antagonist with an IC50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC50s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively[1]. Antidyskinetic effect. Uses: Scientific research. Category: Signaling pathways. CAS No. 23062-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107646. | |
| PD 102807 | PD 102807. Group: Biochemicals. Grades: Purified. CAS No. 23062-91-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD-116152 | PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp. Uses: Pd-116152 has antitumor activity. Synonyms: PD-116,152; PD116,152; PD 116,152; PD116152; PD 116152; 6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester; Methyl 6-formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylate. Grade: >98 %. CAS No. 101708-64-9. Molecular formula: C16H12N2O6. Mole weight: 328.28. | |
| PD-116779 | PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class. Uses: Pd-116779 is a novle antitumor antibiotic. Synonyms: PD116,779; PD 116,779; PD-116,779; PD116779; PD 116779; 3,4-Dihydro-2,3,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; 2,3,8-Trihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. Grade: >98 %. CAS No. 102674-89-5. Molecular formula: C19H14O6. Mole weight: 338.31. | |
| PD 117588 | PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st. Category: Active pharmaceutical ingredients. CAS No. 99734-97-1. Product ID: API99734971. Molecular formula: C20H23F2N3O3. Mole weight: 391.41. |  |
| PD 118057 | PD 118057. Group: Biochemicals. Grades: Purified. CAS No. 313674-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD-118057 | PD-118057 is a hERG channel activator without causing hERG blockade. PD-118057 activates hERG channel to suppress changes in membrane excitability[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313674-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108594. | |
| PD-118576 | PD-118576 is an antitumor macrolide antibiotic produced by Streptomyces sp. WP 3913. It exhibits moderate activity against bacteria and fungi. Synonyms: PD 118576; PD118576; PD-118,576; PD 118,576; PD118,576. CAS No. 100632-37-9. Molecular formula: C33H52O8. Mole weight: 576.8. | |
| PD 123319 ditrifluoroacetate | PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 136676-91-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10259A. | |
| PD 123319 ditrifluoroacetate | PD 123319 ditrifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 130663-39-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 128042 | PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI 976. CAS No. 114289-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107572. | |
| PD 135158 | PD 135158. Group: Biochemicals. Grades: Purified. CAS No. 130285-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 144418 | PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154130-99-1. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108512. | |
| PD146176 | PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC168807. CAS No. 4079-26-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103157. | |
| PD 146176 | PD 146176. Group: Biochemicals. Grades: Purified. CAS No. 4079-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD150606 | PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with Ki values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 179528-45-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100529. | |
| PD 150606 | PD 150606. Group: Biochemicals. Alternative Names: (2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid; (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid. Grades: Highly Purified. CAS No. 179528-45-1. Pack Sizes: 10mg. Molecular Formula: C9H7IO2S, Molecular Weight: 306.12. US Biological Life Sciences. | Worldwide |
| PD 151746 | PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0. Uses: Scientific research. Category: Signaling pathways. CAS No. 181765-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19749. | |
| PD153035 | PD153035 (SU-5271; AG1517; ZM 252868) is a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SU-5271; AG1517; ZM 252868. CAS No. 153436-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14346. | |
| PD158780 | PD158780 is a potent EGFR family inhibitor with IC50s of 8 pM, 49, 52, 52 nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 171179-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-18609. | |
| PD 158780 | PD 158780. Group: Biochemicals. Grades: Purified. CAS No. 171179-06-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 160170 | PD 160170. Group: Biochemicals. Grades: Purified. CAS No. 181468-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 161570 | PD 161570. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H35Cl2N7O. US Biological Life Sciences. | Worldwide |
| PD-161570 | A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells. Group: Biochemicals. Alternative Names: N-[6- (2, 6-Dichlorophenyl) -2-[[4- (diethylamino) butyl]amino]pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl) urea; 1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylamino-butylamino)pyrido[2,3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 192705-80-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PD 166285 | PD 166285. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -2-[[4-[2- (diethylamino) ethoxy]phenyl]amino]-8-methylpyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 212391-63-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H29Cl4N5O2. US Biological Life Sciences. | Worldwide |
| PD 166793 | PD 166793. Group: Biochemicals. Alternative Names: PD 166793-0000; N-[(4'-Bromo[1,1'-biphenyl]-4-yl)sulfonyl]-L-Valine. Grades: Highly Purified. CAS No. 199850-67-4. Pack Sizes: 10mg. Molecular Formula: C17H18BrNO4S, Molecular Weight: 412.3. US Biological Life Sciences. | Worldwide |
| PD 166866 | PD 166866. Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl). Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C20H24N6O3. US Biological Life Sciences. | Worldwide |
| PD-166866 | PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC50 of 52.4 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 192705-79-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101296. | |
| PD-166866 | A novel potent ATP competitive pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors. An inhibitor of the basic fibroplast growth factor (bFGF). Group: Biochemicals. Alternative Names: N-[2-Amino-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]-N'- (1, 1-dimethylethyl). Grades: Highly Purified. CAS No. 192705-79-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PD 168077 maleate | PD 168077 maleate. Group: Biochemicals. Grades: Purified. CAS No. 630117-19-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 168077 Maleate (D4 Dopamine Receptor Agonist, PD 168077 Maleate, PD168077, PD-168077) | A selective D4 dopamine receptor agonist (Ki = 8.7nM, EC50 = 8.3nM). Suitable for central and peripheral delivery. Used in studies of penile erection, learning and memory. Exibits some binding affinity towards human D2 and D3 Receptors (Ki = 2.8uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 630117-19-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD 168368 | PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15-45 nM[1]. PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist[2]. PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 204066-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116216. | |
| PD168393 | PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 194423-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13896. | |
| PD 168568 dihydrochloride | PD 168568 dihydrochloride is a orally active and potent dopamine receptor D4 (DRD4) antagonist. PD 168568 dihydrochloride contains an isoindolinone and is selective for the D4 receptor versus D2 and D3, with Ki values of 8.8, 1842, and 2682 nM, respectively. PD 168568 dihydrochloride can be used for glioblastoma (GBM) research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1782532-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103407A. | |
| PD 168568 dihydrochloride | PD 168568 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 210688-56-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PD 169316 | PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor, with IC50 of 89 nM. PD169316 selectively inhibits the kinase activity of the phosphorylated p38 without hindering upstream kinases to phosphorylate p38. PD169316 shows antiviral activity against Enterovirus71. PD169316 shows antiviral activity against Enterovirus71. Uses: Scientific research. Category: Signaling pathways. CAS No. 152121-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10578. | |
| PD173074 | PD173074 is a potent FGFR1 inhibitor with an IC50 of 25 nM and also inhibits VEGFR2 with an IC50 of 100-200 nM, showing 1000-fold selectivity for FGFR1 over PDGFR and c-Src. Uses: Scientific research. Category: Signaling pathways. CAS No. 219580-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10321. | |
| PD173074 | PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells. Group: Inhibitors. CAS No. 219580-11-7. Pack Sizes: 5mg. Product ID: S1264. Formula: C28H41N7O3. Smiles: CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| PD-173074-[d9] | Labelled PD 173074, a selective FGFR1 and FGFR3 inhibitor. The compound induced a dose-dependent reduce in cell viability and an increase in apoptosis, accompanied by a decrease in extracellular signal-related kinase phosphorylation. Synonyms: PD-173074 D9; N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl-d9)urea. CAS No. 1794979-29-5. Molecular formula: C28H32D9N7O3. Mole weight: 532.73. | |
| PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor) | PD 173074 (PD173074, UNII-A4TLL8634Y, FGF/VEGF Receptor Tyrosine Kinase Inhibitor). Group: Biochemicals. Alternative Names: 1-tert-butyl-3-[2-[4- (diethylamino) butylamino]-6- (3, 5-dimethoxyphenyl) pyrido[2, 3-d]pyrimidin-7-yl]urea. Grades: Highly Purified. CAS No. 219580-11-7. Pack Sizes: 25mg. Molecular Formula: C28 H41 N7O3 , Molecular Weight: 523.7. US Biological Life Sciences. | Worldwide |
| PD173212 | PD173212 is a selective N-type voltage sensitive calcium channel (VSCC) blocker, with an IC50 of 36 nM in IMR-32 assays. Uses: Scientific research. Category: Signaling pathways. CAS No. 217171-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103318. | |
| PD 173212 | PD 173212. Group: Biochemicals. Grades: Purified. CAS No. 217171-01-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PD173952 | PD173952 is a tyrosine kinases inhibitor with IC50s of 0.3, 1.7 and 6.6 nM against Lyn, Abl and Csk, respectively. PD173952 is also a potent Myt1 kinase inhibitor with a Ki of 8.1 nM. PD173952 induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 305820-75-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122113. | |
| PD 173952 | PD 173952. Group: Biochemicals. Alternative Names: 6- (2, 6-Dichlorophenyl) -8-methyl-2-[[4- (4-morpholinyl) phenyl]amino]pyrido[2, 3-d]pyrimidin-7 (8H) -one. Grades: Highly Purified. CAS No. 305820-75-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H21Cl2N5O2. US Biological Life Sciences. | Worldwide |
| PD173955 | PD173955 is an orally active inhibitor of Src (IC50= 22 nM), Yes, Abl, ATP and MAP kinases. PD173955 can effectively prevent the mitotic process and has anticancer activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 260415-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10395. | |
| PD 174265 | PD 174265 is a highly selective, reversible EGFR/ErbB2 tyrosine kinase inhibitor (IC50=0.45 nM) and cell differentiation inducer. By blocking receptor autophosphorylation and the downstream ERK signaling pathway (with an IC50 of 0.45 μM for full-length ERK), PD 174265 effectively inhibits tumor growth and exhibits antitumor activity without obvious toxicity in in vivo models. PD 174265 drives oligodendrocyte precursor cells to switch from a proliferative state to a differentiated state, significantly upregulates the expression of myelin proteins such as CNP, PLP and MBP, and induces neurite branching. PD 174265 shows no inhibitory effect on other kinases including insulin, PDGF and basic FGF receptors, and serves as a crucial tool molecule for investigating the treatment of human epidermoid carcinoma and the mechanism of myelin repair in multiple sclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 216163-53-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112411. | |
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