A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
p-Coumaric acid 4-O-sulfate. Group: Biochemicals. Alternative Names: 3-[4-(Sulfooxy)phenyl]-2-propenoic acid; p-Coumaric acid sulfate. Grades: Highly Purified. CAS No. 376374-66-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C9H8O6S. US Biological Life Sciences.
Worldwide
p-Coumaric Acid 4-O-Sulfate Disodium Salt
p-Coumaric Acid 4-O-Sulfate is the sulfate conjugate of p-Coumaric Acid. p-Coumaric Acid 4-O-Sulfate is one of the metabolites in human biological fluids after coffee consumption. p-Coumaric Acid 4-O-Sulfate is also a metabolite of 4-Nonylphenol. Group: Biochemicals. Alternative Names: 3-[4-(Sulfooxy)phenyl]-2-propenoic Acid Disodium Salt; p-Coumaric Acid Sulfate Disodium Salt. Grades: Highly Purified. CAS No. 308338-96-7. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
p-Coumaric acid-d6
p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: trans-4-Hydroxycinnamic acid-d6. CAS No. 2708298-33-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N0351S1.
p-Coumaric acid ethyl ester
p-Coumaric acid ethyl ester isolated from the herbs of Paederia scandens (Lour.) Merr. Alternative Names: (E)-Ethyl 3-(4-hydroxyphenyl)acrylate. Grades: 98.5%. CAS No. 7362-39-2. Molecular formula: C11H12O3. Mole weight: 192.2.
p-Coumaric acid (p-Hydroxycinnamic acid)
p-Coumaric acid (p-Hydroxycinnamic acid). Group: Biochemicals. Grades: Plant Grade. CAS No. 501-98-4. Pack Sizes: 20mg. US Biological Life Sciences.
p-Coumaroyl-b-D-glucose is a key compound serving as an invaluable precursor or intermediary in the synthesis of wondrous natural products. p-Coumaroyl-b-D-glucose assumes a pivotal role in the research of cancer, inflammation, cardiovascular disorders and other formidable afflictions. Alternative Names: 1-O-(4-Hydroxycinnamoyl)-b-D-glucose; 1-O-(4-Coumaroyl)-b-D-glucose. Grades: 98.0%. CAS No. 7139-64-2. Molecular formula: C15H18O8. Mole weight: 326.30.
p-Coumaroyl-CoA
p-Coumaroyl-CoA (4-Coumaroyl-CoA; p-coumaroylcoenzyme A) is a coenzyme A derivative. p-Coumaroyl-CoA serves as a key intermediate in the biosynthesis of lignin and flavonoids[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Coumaroyl-CoA; p-coumaroylcoenzyme A. CAS No. 30802-00-7. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N11658.
p-Coumaryl alcohol
p-Coumaryl alcohol is a phenylpropanoid compound found in the barks of Cinnamomum cassia Presl. p-Coumaryl alcohol derivatives exhibit the activity of antioxidant. Uses: Antioxidant. Alternative Names: 4-Hydroxycinnamyl alcohol; 3-(p-Hydroxyphenyl) 2-propene 1-ol. Grades: >95%. CAS No. 3690-5-9. Molecular formula: C9H10O2. Mole weight: 150.2.
PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-Chloro-DL-phenylalanine methyl ester hydrochloride. CAS No. 14173-40-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g. Product ID: HY-101456.
pCp-Amine
pCp-Amine is a prominent biomedical product, manifesting as a potent amine-based compound with profound implications in drug development spheres. pCp-Amine is efficacious in precisely targeting designated receptors and enzymes, consequently endowing it with utmost significance as a profound instrument within the research of cancer, neurodegenerative ailments. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C15H28N4O11P2(free acid). Mole weight: 502.35 (free acid).
pCp-Azide
pCp-Azide, an indispensable biochemical reagent renowned for its critical role in facilitating the synthesis of fluorescent probes, is wielded by scientists to map intricate cellular structures. This reagent, a versatile and effective tool, stains proteins, nucleic acids, and carbohydrates to enable their identification and detection. Its unparalleled efficacy and safety have made it a staple in the biomedical industry, underpinning countless diagnostic and therapeutic applications in fields as diverse as oncology and infectious diseases. Alternative Names: Cytidine-5'-phosphate-3'-(15-azido-4,7,10,13-tetraoxa-pentadecanoyl-6-aminohexyl)phosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C26H47N7O16P2(free acid). Mole weight: 775.64 (free acid).
pCp-Biotin
pCp-Biotin is a nucleoside phosphate activator with antiviral effects. It is also an effective anticancer agent. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt; Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Biotin, Triethylammonium salt. Grades: ≥95% by HPLC. Molecular formula: C25H42N6O13P2S1(free acid). Mole weight: 728.65 (free acid).
pCp-Cy3
pCp-Cy3 is a fluorescent dye commonly used in biomedical research, a derivative of Cyanine 3 (Cy3), which emits a red-orange fluorescence when excited by a particular wavelength of light. pCp-Cy3 is utilized for labeling biomolecules such as antibodies and nucleic acids, enabling their visualization and tracking in various biological assays and imaging techniques. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C46H64N6O18P2S2(free acid). Mole weight: 1115.11 (free acid).
pCp-Cy5
pCp-Cy5 is a fluorescent dye used in the realms of cell imaging, flow cytometry and fluorescence microscopy for studying mysteries of cancer and infectious diseases. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C48H66N6O18P2S2(free acid). Mole weight: 1141.14 (free acid).
pCp-Desthiobiotin
pCp-Desthiobiotin, a chemical compound commonly applied in biomedicine, serves as an efficient isolation technique for proteins through affinity purification. It's often employed in tandem with streptavidin to capture and purify biotinylated proteins, thus proving instrumental in research on chronic conditions such as cancer and Alzheimer's. Alternative Names: Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-Desthiobiotin. Grades: ≥ 95 % by HPLC. Molecular formula: C24H42N6O13P2(free acid). Mole weight: 684.57 (free acid).
PCPDTBT
PCPDTBT is a low band gap polymer that is used as a donor material with a high photovoltaic efficiency. It can form blends with a variety of conducting polymers which can be used to enhance the power conversion efficiency (PCE) in an electrochemical device. Alternative Names: Poly[2,6-(4,4-bis-(2-ethylhexyl)-4H-cyclopenta [2,1-b;3,4-b']dithiophene)-alt-4,7(2,1,3-benzothiadiazole)]. CAS No. 920515-34-0. Molecular formula: (C31H38N2S3)n.
p-Cresol
500g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C6H4(CH3)OH. CAS No. 106-44-5. Prepack ID 50551321-500g. Molecular Weight 108.14. See USA prepack pricing.
p-Cresol
p-Cresol is used in the synthesis of Bupranolol (B689650), a non-selective beta blocker. Group: Biochemicals. Alternative Names: 4-Methylphenol; p-Cresol; 1-Hydroxy-4-methylbenzene; 1-Methyl-4-hydroxybenzene; 4-Cresol; 4-Hydroxytoluene; 4-Methylphenol; NSC 3696; p-Cresylic Acid; p-Hydroxytoluene; p-Methylhydroxybenzene; p-Methylphenol; p-Oxytoluene; p-Toluol; p-Tolyl Alcohol. Grades: Highly Purified. CAS No. 106-44-5. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
P-Cresol
P-Cresol. CAS No. 106-44-5. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
p-Cresol-d7
This compound is the labelled analog of a cresol metabolite. Group: Biochemicals. Alternative Names: 4-Methylphenol-d7; 4-(Methyl-d3)-phen-2,3,5,6-d4-ol. Grades: Highly Purified. CAS No. 202325-52-8. Pack Sizes: 10mg, 25mg, 100mg, 250mg. Molecular Formula: C7HD7O. US Biological Life Sciences.
Worldwide
p-Cresol glucuronide
p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 17680-99-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W416250.
P-cresol is a colorless solid with a tar like odor. Sinks and mixes slowly with water. (USCG, 1999);Liquid; PelletsLargeCrystals;Solid;Solid;COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR. TURNS DARK ON EXPOSURE TO AIR AND LIGHT.;Colourless to pink crystals, tarry-smoky medicinal odour;White crystals with a sweet, tarry odor.;Crystalline solid with a sweet, tarry odor. [Note: A liquid above 95°F.]. CAS No. 106-44-5. Molecular formula: C7H8O;CH3C6H4OH;C7H8O. Mole weight: 108.14g/mol. IUPAC Name: 4-methylphenol. SMILES: CC1=CC=C(C=C1)O. InChI: InChI=1S/C7H8O/c1-6-2-4-7(8)5-3-6/h2-5,8H,1H3.
p-Cresol-[methyl-13C]
P-Cresol-[methyl-13C] is the labelled form of p-Cresol. p-Cresol is used in the synthesis of Bupranolol, a non-selective beta blocker. Alternative Names: 4-Methyl-13C-phenol; p-Cresol-α-13C; Phenol-4-(methyl-13C). Grades: 99% by CP; 99% atom 13C. CAS No. 121474-53-1. Molecular formula: C6[13C]H8O. Mole weight: 109.13.
p-Cresol sulfate-d7 potassium
p-Cresol sulfate-d7 (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate-d7 potassium. CAS No. 2469278-96-2. Pack Sizes: 5 mg. Product ID: HY-111431AS.
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate. CAS No. 3233-58-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-111431.
p-Cresyl sulfate potassium
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate potassium. CAS No. 91978-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg. Product ID: HY-111431A.
p-Cresyl sulfate potassium (Standard)
p-Cresyl sulfate (potassium) (Standard) is the analytical standard of p-Cresyl sulfate (potassium). This product is intended for research and analytical applications. p-Cresyl sulfate (p-Tolyl sulfate) potassium is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate potassium shows antiproliferation activity. p-Cresyl sulfate potassium increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate potassium induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: p-Tolyl sulfate potassium (Standard). CAS No. 91978-69-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111431AR.
PCR Stimulant
PCR Stimulant. Pcr stimulant can be used to increase sensitivity and specificity for gc/at-rich template or complex template. it is especially suitable for pfu enzymes. the stock concentration is 5×, and the working concentration can be varied between 0.5× to 2.5×. Group: Cloning Enzymes. Purity: 200ul. Storage: Store at -20 ?. Cat No: CE-3010.
PCSK9-IN-29
PCSK9-IN-29 is a lipid-lowering agent. PCSK9-IN-29 can increase low-density lipoprotein receptor (LDLR) protein expression and decrease PCSK9 protein expression in hepG2 cells. PCSK9-IN-29 can reduce the levels of serum LDL-C, TC, and liver enzyme ALT in crab eating macaques fed a high-fat diet, lower body weight and fat, and increase bone mineral content. PCSK9-IN-29 can be used for research on non-alcoholic fatty liver disease and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1233353-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159595.
PC Spacer Phosphoramidite
PC Spacer phosphoramidite can be used as an intermediate to link any modification reagent (which can be used as phosphoramidite) to the end of the oligonucleotide. After light cleavage, 5'-phosphate is generated on the DNA, making it suitable for further biotransformation, such as gene construction and cloning after ligation. Alternative Names: [4-(4,4'-Dimethoxytrityloxy)butyramidomethyl)-1-(2-nitrophenyl)-ethyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester; 1-[5-[[[4-[Bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester. CAS No. 653575-45-2. Molecular formula: C43H53N4O8P. Mole weight: 784.88.
PC SPDP-NHS carbonate ester
PC SPDP-NHS carbonate ester. Grades: >98.0%. CAS No. 2279944-61-3. Molecular formula: C25H28N4O10S2. Mole weight: 608.64.
PCTFE Products
PCTFE Products.
Pct I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme >90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GAATGCN↑ CTTAC↓GN. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Planococcus citreus SM. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; and 50% glycerol. Cat No: ET-1147RE.
p-Cumenesulphonic acid
p-Cumenesulphonic acid. Alternative Names: p-cumenesulphonic acid;4-Cumenesulfonic acid. CAS No. 16066-35-6. Product ID: ACM16066356. Molecular formula: C9H12O3S. Mole weight: 200.25478. Alfa Chemistry - ISO 9001:32057 Certified.
p-Cyanobenzylidene p-Nonyloxyaniline
CBNOA or CN.9, liquid crystal. CAS No. 67363-89-7. Pack Sizes: Typically in stock: 1g. Mole weight: 348.49. MP/BP: M.P. 71 (S), 99 (N), 105 (I). Order No: FR-0486.
Frinton Laboratories
p-Cymene
p-Cymene is a monoterpene found in several essential oils. p-Cymene exhibits antinociceptive, immunomodulatory, vasorelaxant and neuroprotective activities. Alternative Names: 4-Isopropyltoluene; p-Isopropyltoluene; Dolcymene. CAS No. 99-87-6. Molecular formula: C10H14. Mole weight: 134.22.
PD0166285
PD0166285, a substrate of P-gp, is a WEE1 inhibitor and a weak Myt1 inhibitor with IC50 values of 24 and 72 nM, respectively. PD0166285 exhibits an IC50 of 3.433 μM for Chk1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 185039-89-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13925.
PD0325901
PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine / tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. Uses: Reprogramming, self-renewal. Alternative Names: PD 0325901; PD 325901. Grades: >98%. CAS No. 391210-10-9. Molecular formula: C16H14F3IN2O4. Mole weight: 482.198.
PD0325901 (Mirdametinib)
Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2. Group: Inhibitors. CAS No. 391210-10-9. Pack Sizes: 5mg. Product ID: S1036. Formula: C16H14F3IN2O4. Smiles: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
PD-0332991 (Palbociclib) Hydrochloride
Palbociclib (PD-0332991) HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. Group: Inhibitors. CAS No. 827022-32-2. Pack Sizes: 5mg. Product ID: S1116. Formula: C24H29N7O2.HCl. Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
PD-0332991 (Palbociclib) Isethionate
Palbociclib Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3. Group: Inhibitors. Alternative Names: PD0332991 Isethionate. CAS No. 827022-33-3. Pack Sizes: 50mg. Product ID: S1579. Formula: C24H29N7O2.C2H6O4S. Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.C(CS(=O)(=O)O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
PD 102807
PD 102807 is a M4 muscarinic receptor antagonist with an IC50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC50s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively[1]. Antidyskinetic effect. Uses: Scientific research. Category: Signaling pathways. CAS No. 23062-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107646.
PD 102807
PD 102807. Group: Biochemicals. Grades: Purified. CAS No. 23062-91-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD-116152
PD-116152 is a novel and highly substituted phenazine. It has antitumor activity. It was isolated from the culture broth of a Streptomyces sp. Uses: Pd-116152 has antitumor activity. Alternative Names: PD-116,152; PD116,152; PD 116,152; PD116152; PD 116152; 6-Formyl-4,7,9-trihydroxy-8-methyl-1-phenazinecarboxylic acid methyl ester; Methyl 6-formyl-4,7,9-trihydroxy-8-methylphenazine-1-carboxylate. Grades: >98 %. CAS No. 101708-64-9. Molecular formula: C16H12N2O6. Mole weight: 328.28.
PD-116779
PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class. Uses: Pd-116779 is a novle antitumor antibiotic. Alternative Names: PD116,779; PD 116,779; PD-116,779; PD116779; PD 116779; 3,4-Dihydro-2,3,8-trihydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione; 2,3,8-Trihydroxy-3-methyl-3,4-dihydrotetraphene-1,7,12(2H)-trione. Grades: >98 %. CAS No. 102674-89-5. Molecular formula: C19H14O6. Mole weight: 338.31.
PD 117588
PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st. Category: Active pharmaceutical ingredients. CAS No. 99734-97-1. Product ID: API99734971. Molecular formula: C20H23F2N3O3. Mole weight: 391.41.
PD 118057
PD 118057. Group: Biochemicals. Grades: Purified. CAS No. 313674-97-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD-118057
PD-118057 is a hERG channel activator without causing hERG blockade. PD-118057 activates hERG channel to suppress changes in membrane excitability[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313674-97-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108594.
PD-118576
PD-118576 is an antitumor macrolide antibiotic produced by Streptomyces sp. WP 3913. It exhibits moderate activity against bacteria and fungi. Alternative Names: PD 118576; PD118576; PD-118,576; PD 118,576; PD118,576. CAS No. 100632-37-9. Molecular formula: C33H52O8. Mole weight: 576.8.
PD123319
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. Uses: Vasoconstrictor agents. Alternative Names: PD123319; PD 123319; PD-123319; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (6S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid; (S)-(+)-PD 123319; PD 123319. Grades: >98%. CAS No. 130663-39-7. Molecular formula: C31H32N4O3. Mole weight: 508.61.
PD 123319 ditrifluoroacetate
PD 123319 ditrifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 130663-39-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 123319 ditrifluoroacetate
PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 136676-91-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10259A.
PD 128042
PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC50s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC50=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI 976. CAS No. 114289-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107572.
PD 135158
PD 135158. Group: Biochemicals. Grades: Purified. CAS No. 130285-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 144418
PD 144418 is a very selective sigma 1 agent (Ki values are 0.08 and 1377 nM for σ1 and σ2 respectively), devoid of any significant affinity for other receptors and that sigma 1 site may modulate actions in the CNS. PD 144418 antagonizes mescaline-induced scratching in mice following i.p. administration, and also attenuates cocaine-induced hyperactivity in mice. Alternative Names: PD 144418; PD144418; PD-144418; 1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine. Grades: ≥98% by HPLC. CAS No. 154130-99-1. Molecular formula: C18H22N2O. Mole weight: 282.38.
PD 144418
PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki values of 0.08 nM and 1377 nM for σ1 and σ2 respectively). PD 144418 devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154130-99-1. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108512.
PD146176
PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC168807. CAS No. 4079-26-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103157.
PD 146176
PD 146176. Group: Biochemicals. Grades: Purified. CAS No. 4079-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD150606
PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with Ki values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 179528-45-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-100529.
PD 150606
PD 150606. Group: Biochemicals. Alternative Names: (2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid; (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic Acid. Grades: Highly Purified. CAS No. 179528-45-1. Pack Sizes: 10mg. Molecular Formula: C9H7IO2S, Molecular Weight: 306.12. US Biological Life Sciences.
Worldwide
PD 151746
PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0. Uses: Scientific research. Category: Signaling pathways. CAS No. 181765-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19749.
PD153035
PD153035 (SU-5271; AG1517; ZM 252868) is a potent EGFR inhibitor with Ki and IC50 of 6 and 25 pM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SU-5271; AG1517; ZM 252868. CAS No. 153436-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14346.
PD158780
PD158780 is a potent EGFR family inhibitor with IC50s of 8 pM, 49, 52, 52 nM for EGFR, ErbB2, ErbB3, and ErbB4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 171179-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-18609.
PD 158780
PD 158780. Group: Biochemicals. Grades: Purified. CAS No. 171179-06-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 160170
PD 160170. Group: Biochemicals. Grades: Purified. CAS No. 181468-88-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.