A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
PD176252 is a potent antagonist of neuromedin-B preferring (BB1) and gastrin-releasing peptide-preferring (BB2) receptor with Kis of 0.17 nM and 1 nM for human BB1 and BB2 receptors, and 0.66 nM, 16 nM for Rat BB1 and BB2 receptors, respectively; PD176252 is also an agonist of N-Formyl peptide receptor1/2 (FPR1/FPR2), with EC50s of 0.31 and 0.66 μM in HL-60 cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 204067-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103286.
PD 176252
PD 176252. Group: Biochemicals. Grades: Purified. CAS No. 204067-01-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PD 176252
PD 176252. CAS No: 204067-01-6
Sarchem Laboratories New Jersey NJ
PD180970
PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 287204-45-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103274.
PD 184161
PD 184161. Group: Biochemicals. Alternative Names: 5-Bromo-2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide. Grades: Highly Purified. CAS No. 212631-67-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H13BrClF2IN2O2. US Biological Life Sciences.
Worldwide
PD 184352
PD 184352. Group: Biochemicals. Alternative Names: 2-[(2-Chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; 3, 4-Difluoro-2- (2-chloro-4-iodophenylamino) -N-cyclopropyl methoxybenzamide; CI 1040. Grades: Highly Purified. CAS No. 212631-79-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C17H14ClF2IN2O2. US Biological Life Sciences.
Worldwide
PD 198306
PD 198306. Group: Biochemicals. Grades: Purified. CAS No. 212631-61-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PD 198306
PD 198306 is a selective MAPK/ERK-kinase (MEK) inhibitor. PD 198306 results in an observable reduction in the Streptozocin induced increase in the level of active ERK1 and 2. Antihyperalgesic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 212631-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107620.
PD-1 (Intracellular Domain) Antibody [G6H24]
PD-1 (Intracellular Domain) Antibody [G6H24]. Group: Antibodies. Alternative Names: Programmed cell death protein 1, Protein PD-1, Pdcd1, Pd1. Pack Sizes: 20uL. Product ID: F3016. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
PD-1/PD-L1-IN-29
PD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2665734-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-152240.
PD-1/PD-L1 Inhibitor 3
PD-1/PD-L1 Inhibitor 3 is a PD-1/PD-L1 interaction inhibitor with IC50 value of 5.6 nM. Synonyms: Programmed Death-1/Programmed Death-Ligand 1 Inhibitor 3. Grade: ≥97% by HPLC. CAS No. 1629654-95-0. Molecular formula: C89H126N24O18S. Mole weight: 1852.2.
Pd2dba3 (Tris(dibenzylideneacetone)dipalladium(0)). CAS No: 51364-51-3
Sarchem Laboratories New Jersey NJ
PD318088
PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352 (HY-50295). PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 391210-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12062.
PD 334581
PD 334581. Group: Biochemicals. Grades: Purified. CAS No. 548756-68-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 404182
PD 404182. Alternative Names: 3,4-Dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. CAS No. 72596-74-8. Product ID: ACM72596748-1. Molecular formula: C11H11N3S. Mole weight: 217.29. IUPAC Name: 3,4-dihydro-2H-pyrimido[1,2-c][1,3]benzothiazin-6-imine. Canonical SMILES: C1CN=C2C3=CC=CC=C3SC(=N)N2C1. Alfa Chemistry - ISO 9001:32057 Certified.
PD 407824
PD 407824 is a checkpoint kinase Chk1 and WEE1 inhibitor with IC50s of 47 and 97 nM, respectively. PD 407824 is a chemical BMP sensitizer and increases the sensitivity of cells to sub-threshold amounts of BMP4[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 622864-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18961.
PD 81723
PD 81723. Group: Biochemicals. Grades: Purified. CAS No. 132861-87-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 90780
PD 90780 is a non peptide antagonist of nerve growth factor (NGF). PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 77422-99-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110166.
PD 90780
PD 90780. Group: Biochemicals. Grades: Purified. CAS No. 77422-99-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD98059
PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 μM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 μM) and MEK2 (IC50 of 50 μM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 167869-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12028.
PD 98059
PD 98059. Group: Biochemicals. Grades: Purified. CAS No. 167869-21-8. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
PD 98059
PD98059 is a non-ATP competitive MEK inhibitor with IC50 of 2 μM in a cell-free assay, specifically inhibits MEK-1-mediated activation of MAPK; does not directly inhibit ERK1 or ERK2. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR) and functions as an AHR antagonist. Group: Inhibitors. CAS No. 167869-21-8. Pack Sizes: 10mg. Product ID: S1177. Formula: C16H13NO3. Smiles: COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2. Storage Conditions: 2 years -80 in solvent.
United States; Europe
pdBD-2
pdBD-2 is an antimicrobial peptide found in Chinese loach, Paramisgurnus dabryanus. It has anti-gram-positive bacteria and gram-negative bacteria activity. Synonyms: Paramisgurnus dabryanus beta defensin 2. Grade: >98%.
PDBT-T1
Band gap: 1.93 eV. Alternative Names: Poly[[5,10-bis(5-octyl-2-thienyl)dithieno[2,3-d:2',3'-d']benzo[1,2-b:4,5-b']dithiophene-2,7-diyl]-2,5-thiophenediyl[5,7-bis(2-ethylhexyl)-4,8-dioxo-4H,8H-benzo[1,2-c:4,5-c']dithiophene-1,3-diyl]-2,5-thiophenediyl]. CAS No. 1701403-91-9. Molecular formula: (C72H78O2S10)n.
PDC31
PDC31 (THG113.31; ILGHXDYK) is an allosteric and non-competitive inhibitor of FP Prostaglandin Receptor. PDC31 is the D-amino acid-based oligopeptide, is used for smooth muscle contractile agent. PDC31 decreases the strength and duration of uterine contractions in vivo, which can be used for research of preterm labor and primary dysmenorrhea (PD). PDC31 also enhances Ca2+-dependent large-conductance K+-channel in human myometrial cells[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: THG113.31; ILGHXDYK. CAS No. 634586-40-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4160.
PDCDT
PDCDT. Alternative Names: N N-BIS(2 5-DI-T-BU-PHENYL)-3 4 9 10-;N,N-bis(2,5-di-T-bu-phenyl)-3,4,9,10-perylenedic;N,N-bis(2,5-di-T-butylphenyl)-3,4*9,10-perylened;N,N-BIS(2,5-DI-T-BU-PHENYL)-3,4,9,10-PE RYLENEDICARBOXIMIDE;2,9-BIS(2,5-BIS(1,1-DIMETHYLETHYL)PHENYL)-ANTRA(2,19-DEF:6. CAS No. 83054-80-2. Molecular formula: C52H50N2O4. Mole weight: 767g/mol. IUPAC Name: 7,18-bis(2,5-ditert-butylphenyl)-7,18-diazaheptacyclo[14.6.2.22,5.03,12.04,9.013,23.020,24]hexacosa-1(23),2,4,9,11,13,15,20(24),21,25-decaene-6,8,17,19-tetrone. SMILES: CC(C)(C)C1=CC(=C(C=C1)C(C)(C)C)N2C(=O)C3=C4C(=CC=C5C4=C(C=C3)C6=C7C5=CC=C8C7=C(C=C6)C(=O)N(C8=O)C9=C(C=CC(=C9)C(C)(C)C)C(C)(C)C)C2=O. InChI: InChI=1S/C52H50N2O4/c1-49(2,3)27-13-23-37(51(7,8)9)39(25-27)53-45(55)33-19-15-29-31-17-21-35-44-36(22-18-32(42(31)44)30-16-20-34(46(53)56)43(33)41(29)30)48(58)54(47(35)57)40-26-28(50(4,5)6)14-24-38(40)52(10,11)12/h13-26H,1-12H3.
PdCl2(Amphos)2
PdCl2(Amphos)2 is a highly efficient palladium catalyst. PdCl2(Amphos)2 can be used in research related to organic synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 887919-35-9. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-W010686.
PDD00017272
PDD00017272 is an inhibitor of poly(ADP-ribose) glycohydrolase (PARG) (EC50=4.8 nM) and an activator of PARP1/2. PDD00017272 inhibits its activity of hydrolyzing poly(ADP-ribose) (pADPr), resulting in the accumulation of pADPr on chromatin, interfering with DNA damage repair and replication processes, and inducing PARP1/2-dependent cytotoxicity. PDD00017272 can be used in cancer models with DNA repair defects (such as BRCA mutations) or resistance to PARP inhibitors. PDD00017272 has a PARG expression level-correlated inhibitory potency with EC50 of 9.2 nM (PARG cells), the tumor cells with lower PARG expression are more sensitive[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945950-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133531.
PDD00017273
PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with an IC50 of 26 nM. PDD00017273 exhibits >350-fold selectivity for PARG over a panel of ion channels, enzymes and receptors, including PARP1 and ARH3. Group: Inhibitors. CAS No. 1945950-21-9. Pack Sizes: 5mg. Product ID: S8862. Formula: C23H26N6O4S2. Smiles: CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN=C(S5)C)C. Storage Conditions: 3 years -20°C powder.
United States; Europe
PDD 00017273
PDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945950-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108360.
PDE10-IN-5
PDE10-IN-5 is a phosphodiesterase 10 (PDE 10) inhibitor, can be used for researching certain central nervous system (CNS) disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 898562-99-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14550A.
PDE12-IN-1
PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC50 value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2,5-linked adenylate polymers (2-5A) levels, and the pEC50 value is 7.7. PDE12-IN-1 shows antiviral activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259620-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117318.
PDE1B active from Rat, Recombinant
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene. Rat pde1b (genbank accession no. nm_022710) full length with n-terminal his-gst-tag, mw=89kda, expressed in a baculovirus infected sf9 cell expression system. Group: Enzymes. Synonyms: PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Purity: > 70% (SDS-PAGE). PDE. Mole weight: mol wt 89 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE1B; PDE1B1; PDES1B; phosphodiesterase 1B. Cat No: NATE-0517.
PDE4A10 active from Human, Recombinant
Human PDE4A10, also known as PDE4A protein isoform 6, transcript variant 3 (GenBank Accession No. NM_001111309) amino acids 2-825 (end) with N-terminal GST-tag, MW=117 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Uman pde4a10, also known as pde4a protein isoform 6, transcript variant 3 (genbank accession no. nm_001111309) amino acids 2-825 (end) with n-terminal gst-tag, mw=117 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 75% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 117 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0523.
PDE4A4B active from Human, Recombinant
Human PDE4A4B, also known as PDE4A isoform 1 (GenBank Accession No. NM_001111307) amino acids 2-end with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4a4b, also known as pde4a isoform 1 (genbank accession no. nm_001111307) amino acids 2-end with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Purity: > 40% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific; PDE4A10; PDE4A. Cat No: NATE-0524.
PDE4B-IN-2
PDE4B-IN-2 is an orally active and selective PDE4B inhibitor with an IC50 of 15 nM. PDE4B-IN-2 inhibits PDE4D (IC50=1.7 μM). PDE4B-IN-2 exhibits potent anti-inflammatory effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 915082-52-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115687.
PDE4B modulator-1
PDE4B modulator-1 is a PDE4B modulator. Uses: Scientific research. Category: Signaling pathways. CAS No. 848057-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-180878.
PDE4D2 active from Human, Recombinant
Human PDE4D2 (GenBank Accession No. NM_001197221) amino acids 2-507 (end) with N-terminal GST-tag, MW=84 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d2 (genbank accession no. nm_001197221) amino acids 2-507 (end) with n-terminal gst-tag, mw=84 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 80% (SDS-PAGE). PDE. Mole weight: mol wt 84 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0525.
PDE4D7 active from Human, Recombinant
Human PDE4D7 (GenBank Accession No. NM_001165899) amino acids 2-748 (end) with N-terminal GST-tag, MW=111 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Human pde4d7 (genbank accession no. nm_001165899) amino acids 2-748 (end) with n-terminal gst-tag, mw=111 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 111 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. DPDE3; PDE43; STRK1; phosphodiesterase 4D, cAMP-specific; PDE4D2; PDE4D. Cat No: NATE-0526.
PDE4-IN-24
PDE4-IN-24 (compoud 14h) is a potent inhibitor of PDE4D with the IC50 of 0.57 nM and >4100-fold selectivity over other PDE families. PDE4-IN-24 plays an important role in inflammatory disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3087059-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169981.
PDE5A1 active from Mouse, Recombinant
Mouse PDE5A (GenBank Accession No. NM_153422) full length with N-terminal GST-tag, MW=124 kDa, expressed in a Baculovirus infected Sf9 cell expression system. Mouse pde5a (genbank accession no. nm_153422) full length with n-terminal gst-tag, mw=124 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Purity: > 70% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 124 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A. Cat No: NATE-0528.
PDE5-IN-4
PDE5-IN-4 is a phosphodiesterase 5 inhibitor. PDE5-IN-4 can be used for the research of acute myocardial infarction and damage caused by reperfusion, gastrointestinal diseases, damage caused by diabetes, and liver failure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 224788-36-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-142059.
PDE7A-IN-1
PDE7A-IN-1 is an orally active and selective PDE7A inhibitor with an IC50 of 0.0037 μM against PDE7A. PDE7A-IN-1 shows excellent isozyme selectivity over PDE7B. PDE7A-IN-1 elevates intracellular cAMP levels, suppresses ECR5 enhancer activity and reduces sclerostin expression. PDE7A-IN-1 significantly increases bone mineral density in rats. PDE7A-IN-1 can be used for the study of osteoporosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3074559-75-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-170788.
PDE7B active from Mouse, Recombinant
Mouse PDE7B (GenBank Accession No. NM_013875) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Mouse pde7b (genbank accession no. nm_013875) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 65% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0531.
PDE7B active from Rat, Recombinant
Rat PDE7B (GenBank Accession No. NM_080894) amino acids 108-446 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Rat pde7b (genbank accession no. nm_080894) amino acids 108-446 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Purity: > 30% (SDS-PAGE). PDE. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B. Cat No: NATE-0532.
PDE7-IN-3
Pde7-in-3 (example 2) is an inhibitor of the phosphodiesterase PDE7 with potential analgesic activity. PDE7-IN-3 can be used to study inflammatory, neuropathic, visceral and nociceptive pain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 908570-13-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100326.
PDEC-NB
PDEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC). Uses: Scientific research. Category: Signaling pathways. CAS No. 874302-76-8. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126498.
p-Decyloxyaniline
Off-white powder, 99%. CAS No. 39905-47-0. Pack Sizes: Typically in stock: 5g, 25g. Mole weight: 249.4. MP/BP: M.P. 48-50, B.P. 184-188/1 mm. Order No: FR-1212.
Frinton Laboratories
p-Decyloxybenzylidene p-Toluidine
10O.1, liquid crystal. CAS No. 53764-62-8. Pack Sizes: Typically in stock: 2g. Mole weight: 351.53. MP/BP: M.P. 65 (S), 75 (N), 79 (I). Order No: FR-1201.
PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2209053-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111507.
PDGFRb/RAF Kinase Inhibitor
An orally bioavailable amino-triazole compound that is shown to bind to the inactive conformations of both PDGFRb and Raf kinases (allosteric, Type II inh), and acts as a potent inhibitor of Flt3, Kit, PDGFRa and PDGFRb (=52, 170, 300 and 520nM, respectively) with selectivity over B-Raf, p38a, FGFR2 and VEGFR2 (>10uM) in a multi-kinase panel. Completely blocks the phosphorylations of MEK-1/2 S217/S221, ERK-1/2 T202/Y204 in FGF-stimulated HUVECs, PDGFRb in PDGF-BB-stimulated VSMCs, ERK-1/2 T202/Y204 in 1205Lu-B Raf V600E cells, and C-Raf S338 at 10uM. Reduces FGF-induced angiogenesis in mouse Matrigel model (50mg/kg, i.p., bid) and selectively induces apoptosis in the endothelium; further, suppresses orthotopic renal cell carcinoma growth in mice (100mg/kg, p.o., qd). Group: Biochemicals. Alternative Names: 6- (4- (5- (3- (Trifluoromethyl) phenylamino) -4 H-1,2,4-triazol-3-yl)phenoxy)-2-(methylthio)pyrimidin-4-amine, PDGFR Tyrosine Kinase Inhibitor XXII. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?OS, Molecular Weight: 459.6. US Biological Life Sciences.
Worldwide
Pd/graphene nanocomposite
Pd/graphene nanocomposite.
PDHK-IN-4
PDHK-IN-4 (Compound 30) is a potent inhibitor of PDHK with IC50s of 0.0051 and 0.0122 μM for PDHK2 and PDHK4, repectively. Pyruvate dehydrogenase kinases (PDHKs) are fascinating agent targets for numerous diseases, including diabetes and cancers. PDHK-IN-4 has the potential for the research of cancer diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3065641-69-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-146552.
PDI2
PDI2 (PSMA-DOTA-PEI2) is a prostate-specific membrane antigen (PSMA) ligand that acts as a tumor retention agent, renal uptake reducer, imaging agent and antitumor agent, applicable in SPECT diagnostic imaging and radiotheranostics. PDI2 specifically binds to PSMA on prostate cancer cells, enters cells via clathrin-dependent endocytosis, and exhibits higher tumor retention rate and lower renal uptake level. PDI2 is applicable in research related to prostate cancer and castration-resistant metastatic prostate cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PSMA-DOTA-PEI2. CAS No. 3110124-60-9. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P11591.
Band gap: 1.6 eV. Alternative Names: Perylene diimide flanked diketopyrrolopyrrole,nPDI2DPP. CAS No. 2083628-79-7. SMILES: O=C1C(C2=C(C3=CC=C(C4=CC(C(N(C(CC)CC)C5=O)=O)=C(C5=CC(N6CCCCCC)=C78)C7=C4C9=CC=C%10C%11=C(C(N(C(CC)CC)C%10=O)=O)C=C6C8=C9%11)S3)N1CCCCCCCC)=C(C%12=CC=C(C%13=CC(C(N(C(CC)CC)C%14=O)=O)=C(C%14=CC(N%15CCCCCC)=C%16%17)C%16=C%13C%18=CC=C%19C%20=C(C(N(C(CC)CC)C%.
p-Diethylanilinesulfonic acid
p-Diethylanilinesulfonic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 35478-73-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C10H15NO3S. US Biological Life Sciences.
Worldwide
PDI-IN-3
PDI-IN-3 (compound 16F16) is a protein disulfide isomerase (PDI) inhibitor. PDI-IN-3 inhibits cell viability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 922507-80-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-124866.
p-Dimethylaminoacetophenone
Yellow powder. CAS No. 2124-31-4. Pack Sizes: Typically in stock: 10g, 50g. Mole weight: 163.22. MP/BP: M.P. 101-102. Order No: FR-0494.
Frinton Laboratories
p- (Dimethylamino) benzenesulfonic acid
p- (Dimethylamino) benzenesulfonic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 121-58-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C8H11NO3S. US Biological Life Sciences.
Worldwide
p-Dimethylaminobenzylidene p-Anisidine
induces mesomorphic phases. CAS No. 1749-04-8. Pack Sizes: Typically in stock: 1g. Mole weight: 254.33. MP/BP: M.P. 139-140. Order No: FR-0707.
Frinton Laboratories
p-Dimethylaminobenzylidene p-Phenetidine
Induces mesomorphism. CAS No. 15484-93-2. Pack Sizes: Typically in stock: 2g. Mole weight: 268.36. MP/BP: M.P. 146-147. Order No: FR-0264.
Frinton Laboratories
p- (Dimethylamino) nitrosobenzene
p- (Dimethylamino) nitrosobenzene. Group: Biochemicals. Alternative Names: p- (N, N-Dimethylamino) nitrosobenzene; p-NDMA; p-Nitroso-N,N-dimethylaniline; 1-(Dimethylamino)-4-nitrosobenzene; 4- (Dimethylamino) nitrosobenzene; 4-Nitroso-N,N-dimethylaminobenzene; 4-Nitroso-N,N-dimethylaniline; Accelerine; N,N-Dimethyl-4-nitrosoaniline; N,N-Dimethyl-4-nitrosobenzenamine; N,N-dimethyl-p-nitrosoaniline; N,N-Dimethyl-p-nitrosoaniline; NDMA; NSC 2775; Ultra Brilliant Blue P; N,N-Dimethyl-4-nitrosobenzenamine. Grades: Highly Purified. CAS No. 138-89-6. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
p-Dioxanone
Dioxanone. CAS No. 3041-16-5. Categories: 1,4-dioxan-2-one.
Pennsylvania PA
P-Dioxanone
P-Dioxanone. CAS No: 3041-16-5
Sarchem Laboratories New Jersey NJ
p-Divinylbenzene
p-Divinylbenzene(DVB) is a cross-linking agent, which is used in a variety of polymeric processes such as copolymerization of styrene to improve the thermo-mechanical properties of the composite. Alternative Names: 1,4-Diethenylbenzene, 1,4-Divinylbenzene. CAS No. 105-06-6. Molecular formula: C10H10. Mole weight: 130.19. IUPAC Name: 1,4-bis(ethenyl)benzene. SMILES: C=Cc1ccc(C=C)cc1. InChI: 1S/C10H10/c1-3-9-5-7-10(4-2)8-6-9/h3-8H,1-2H2.
PDK4-IN-1
PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 has antidiabetic, anticancer and anti-allergic activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2310262-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-135954.