A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Paired box protein Pax-5 (311-319) is a bioactive peptide of Paired box protein Pax-5. Paired box protein Pax-5 is a transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Alternative Names: B-cell-specific transcription factor (311-319).
PA Janelia Fluor 549, SE
PA Janelia Fluor 549, SE is a photoactivatable and cell-permeable yellow fluorescent dye. It is suitable for single molecule tracking and super resolution microscopy in live cells. Alternative Names: 2,5-Dioxo-1-pyrrolidinyl 3',6'-di-1-azetidinyl-2-diazo-2,3-dihydro-3-oxospiro[1H-indene-1,9'-[9H]xanthene]-6-carboxylate. CAS No. 1811539-42-0. Molecular formula: C32H25N5O6. Mole weight: 575.58.
PA Janelia Fluor® 646, SE
PA Janelia Fluor® 646, SE (PA-JF646-NHS) is a photo-activatable fluorescent dye. PA Janelia Fluor® 646, SE is a far-red light-excited, 405nm-activated NHS ester-based dye (λex/em = 650/664 nm). PA Janelia Fluor® 646, SE can achieve extremely low background and single-molecule-level ultra-high-resolution imaging through photo-controlled switching, making it a powerful tool for live cell super-resolution microscopy technology. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PA-JF646-NHS. CAS No. 2093120-32-0. Pack Sizes: 100 μg. Product ID: HY-133535.
PAK4-IN-2
PAK4-IN-2 is a highly potent PAK4 inhibitor with IC50 value of 2.7 nM. PAK4-IN-2 can arrest MV4-11 cells at G0/G1 phase and induce cell apoptosis. PAK4-IN-2 can be used for researching cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2488706-33-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143490.
Palacaparib
AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD+?breast cancer and advanced solid malignancies research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-9574. CAS No. 2756333-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145804.
PalA I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and 95% of these can be recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GG↑CGCGCC CCGCGC↓GG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E. coli strain , that carries the cloned gene from Pseudomanas alcaligenes BS17. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1143RE.
Palatinitol
100mg Pack Size. Group: Building Blocks, Carbohydrates. Formula: C12H24O11. CAS No. 64519-82-0. Prepack ID 28517137-100mg. Molecular Weight 344.31. See USA prepack pricing.
Palatinitol
1g Pack Size. Group: Building Blocks, Carbohydrates. Formula: C12H24O11. CAS No. 64519-82-0. Prepack ID 28517137-1g. Molecular Weight 344.31. See USA prepack pricing.
Palatinose
Palatinose. CAS No. 13718-94-0. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Palatinose
25g Pack Size. Group: Carbohydrates, Sugars. Formula: C12H22O11. CAS No. 13718-94-0. Prepack ID 17108147-25g. Molecular Weight 342.3. See USA prepack pricing.
Palatinose Hydrate
Isomaltulose is another sugar substitute, and non-cariogenic substance. Alternative Names: D-Fructose, 6-O-α-D-glucopyranosyl-, hydrate; 6-O-α-D-Glucopyranosyl-D-Fructose Hydrate; Isomaltulose Hydrate. Grades: ≥99%. CAS No. 343336-76-5. Molecular formula: C12H22O11.xH2O. Mole weight: 342.30 (anhydrous basis).
Palatinose Monohydrate
Palatinose Hydrate, a natural occurring disaccharide composed of α-1,6-linked glucose and fructose, can be used as an alternative sugar. Because it is absorbed more slowly than sucrose, it can be used as a sweetener for diabetic patients. Alternative Names: D-Fructose, 6-O-α-D-glucopyranosyl-, monohydrate; Isomaltulose monohydrate; 6-O-α-D-Glucopyranosyl-D-fructose monohydrate; Palatinose hydrate; Isomaltulose hydrate. CAS No. 58024-13-8. Molecular formula: C12H22O11.H2O. Mole weight: 360.31.
Palazestrant
Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC50 value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC50 value of 1.4-1.6 nM. Palazestrant can inhibit ER+/HER2+ cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OP-1250. CAS No. 2092925-89-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-148789.
Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PD 0332991. CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-50767.
Palbociclib
Palbociclib is an orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. Alternative Names: PD 0332991; PD0332991; PD-0332991; Ibrance; 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: 98%. CAS No. 571190-30-2. Molecular formula: C24H29N7O2. Mole weight: 447.53.
Palbociclib
Palbociclib is a selective CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib is a drug for the treatment of ER-positive and HER2-negative breast cancer. Category: Active pharmaceutical ingredients. CAS No. 571190-30-2. Product ID: API571190302. Molecular formula: C24H29N7O2. Mole weight: 447.533.
Palbociclib HCl
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4 / cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein phosphorylation; inhibition of Rb phosphorylation prevents Rb-positive tumor cells from entering the S phase of the cell cycle (arrest in the G1 phase), resulting in suppression of DNA replication and decreased tumor cell proliferation. PD 0332991 is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) (IC50=0.011 μmol/L) and Cdk6 (IC50=0.016 μmol/L), having no activity against a panel of 36 additional protein kinases. Alternative Names: PD 0332991; PD 332991; PD0332991; PD-0332991; Palbociclib hydrochloride. Grades: >98%. CAS No. 827022-32-2. Molecular formula: C24H29N7O2.HCl. Mole weight: 483.99.
Palbociclib hydrochloride
Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[1][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PD-0332991 hydrochloride. CAS No. 571189-11-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g; 2 g. Product ID: HY-50767C.
Palbociclib Impurity 002
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C14H21BrN4. Mole weight: 325.25.
Palbociclib Impurity 022
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; 1779124-68-3; tert-Butyl4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; SCHEMBL17550837; CS-0448403; EN300-7455913. Grades: 95%. CAS No. 1779124-68-3. Molecular formula: C14H20N4O4. Mole weight: 308.33.
Palbociclib Impurity 025
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: N-Formyl Palbociclib; Palbociclib Impurity F; Palbociclib N-Aldehyde; Palbociclib N-Formyl Impurity. Grades: 95%. CAS No. 2174002-16-3. Molecular formula: C25H29N7O3. Mole weight: 475.54.
Palbociclib Impurity 026
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C28H37N7O2. Mole weight: 503.64.
Palbociclib Impurity 027
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C27H35N7O2. Mole weight: 489.61.
Palbociclib Impurity 028
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Molecular formula: C18H24N4O. Mole weight: 312.41.
Palbociclib Impurity 029
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: 1-(2-nitropyridin-3-yl)piperazine; 1566082-34-5; GS0805; EN300-2138375. Grades: 95%. CAS No. 1566082-34-5. Molecular formula: C9H12N4O2. Mole weight: 208.22.
Palbociclib Impurity 030
An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. . Alternative Names: 1-(4-nitropyridin-3-yl)piperazine; GS0814; 1211541-02-4. Grades: 95%. CAS No. 1211541-02-4. Molecular formula: C9H12N4O2. Mole weight: 208.22.
Palbociclib Impurity 1
Palbociclib Impurity 1. Uses: For analytical and research use. CAS No. 571190-22-2. Molecular formula: C22H27N7O. Mole weight: 405.51. Catalog: APB571190222.
Palbociclib Impurity 10
Palbociclib Impurity 10 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Alternative Names: 1-Piperazinecarboxylic acid, 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis-, 1,1'-bis(1,1-dimethylethyl) ester; 1,1'-Bis(1,1-dimethylethyl) 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis[1-piperazinecarboxylate]; Bis(2-methyl-2-propanyl) 4,4'-[(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]di(1-piperazinecarboxylate). Grades: 95%. CAS No. 2206135-30-8. Molecular formula: C41H55N11O5. Mole weight: 781.94.
Palbociclib Impurity 11
Palbociclib Impurity 11. Uses: For analytical and research use. CAS No. 866084-31-3. Molecular formula: C33H45N7O4. Mole weight: 603.77. Catalog: APB866084313.
Palbociclib Impurity 14
Palbociclib Impurity 14. Uses: For analytical and research use. CAS No. 51534-87-3. Molecular formula: C9H16O4. Mole weight: 188.22. Catalog: APB51534873.
Palbociclib Impurity 15
Palbociclib Impurity 15. Uses: For analytical and research use. CAS No. 51534-82-8. Molecular formula: C9H16O5. Mole weight: 204.22. Catalog: APB51534828.
Palbociclib Impurity 17
Palbociclib Impurity 17. Uses: For analytical and research use. CAS No. 1439-36-7. Molecular formula: C21H19OP. Mole weight: 318.36. Catalog: APB1439367.
Palbociclib Impurity 18
Palbociclib Impurity 18. Uses: For analytical and research use. CAS No. 1244949-62-9. Molecular formula: C11H14ClN3O. Mole weight: 239.7. Catalog: APB1244949629.
Palbociclib Impurity 19
Palbociclib Impurity 19. Uses: For analytical and research use. CAS No. 571191-15-6. Molecular formula: C22H27N7O2. Mole weight: 421.5. Catalog: APB571191156.
Palbociclib Impurity 2
Palbociclib Impurity 2. Uses: For analytical and research use. CAS No. 1072-97-5. Molecular formula: C5H5BrN2. Mole weight: 173.01. Catalog: APB1072975.
Palbociclib Impurity 2
Palbociclib Impurity 2 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Alternative Names: Desoxo-palbociclib; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 8-Cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity D. Grades: 95%. CAS No. 2204863-06-7. Molecular formula: C24H29N7O. Mole weight: 431.53.
Palbociclib Impurity 21
Palbociclib Impurity 21. Uses: For analytical and research use. Alternative Names: di-tert-butyl 4,4'-(6,6'-((8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(azanediyl))bis(pyridine-6,3-diyl))bis(piperazine-1-carboxylate). CAS No. 2206135-30-8. Molecular formula: C41H55N11O5. Mole weight: 781.95. Catalog: APB2206135308.
Palbociclib Impurity 21
Palbociclib Impurity 21. Uses: For analytical and research use. CAS No. 2098673-40-4. Molecular formula: C24H29N7O3. Mole weight: 463.54. Catalog: APB2098673404.
Palbociclib Impurity 23
Palbociclib Impurity 23. Uses: For analytical and research use. CAS No. 2205035-04-5. Molecular formula: C24H29N7O2. Mole weight: 447.54. Catalog: APB2205035045.
Palbociclib Impurity 24
Palbociclib Impurity 24. Uses: For analytical and research use. CAS No. 1013916-37-4. Molecular formula: C13H14ClN3O. Mole weight: 263.72. Catalog: APB1013916374.
Palbociclib Impurity 25
Palbociclib Impurity 25. Uses: For analytical and research use. Molecular formula: C15H17N3O3. Mole weight: 287.32. Catalog: APB09487.
Palbociclib Impurity 26
Palbociclib Impurity 26. Uses: For analytical and research use. CAS No. 2172256-78-7. Molecular formula: C15H17N3O3. Mole weight: 287.32. Catalog: APB2172256787.
Palbociclib Impurity 27
Palbociclib Impurity 27. Uses: For analytical and research use. Molecular formula: C36H49N7O12. Mole weight: 771.83. Catalog: APB09489.
Palbociclib Impurity 28
Palbociclib Impurity 28. Uses: For analytical and research use. Molecular formula: C36H49N7O12. Mole weight: 771.83. Catalog: APB09488.
Palbociclib Impurity 29
Palbociclib Impurity 29. Uses: For analytical and research use. Molecular formula: C24H31N7O3. Mole weight: 465.56. Catalog: APB09490.
Palbociclib Impurity 30
Palbociclib Impurity 30. Uses: For analytical and research use. CAS No. 1974279-21-4. Molecular formula: C28H33N7O5. Mole weight: 547.62. Catalog: APB1974279214.
Palbociclib Impurity 31
Palbociclib Impurity 31. Uses: For analytical and research use. CAS No. 2363172-64-7. Molecular formula: C20H22N6O2. Mole weight: 378.44. Catalog: APB2363172647.
Palbociclib Impurity 32
Palbociclib Impurity 32. Uses: For analytical and research use. Molecular formula: C24H25N7O4. Mole weight: 475.51. Catalog: APB09491.
Palbociclib Impurity 33
Palbociclib Impurity 33. Uses: For analytical and research use. CAS No. 733038-80-7. Molecular formula: C23H32BrN7O2. Mole weight: 518.46. Catalog: APB733038807.
Palbociclib Impurity 34
Palbociclib Impurity 34. Uses: For analytical and research use. Molecular formula: C18H22BrClN6O2. Mole weight: 469.77. Catalog: APB09492.
Palbociclib Impurity 35
Palbociclib Impurity 35. Uses: For analytical and research use. CAS No. 2410426-60-5. Molecular formula: C22H30BrN5O3. Mole weight: 492.42. Catalog: APB2410426605.
Palbociclib Impurity 36
Palbociclib Impurity 36. Uses: For analytical and research use. CAS No. 1206248-85-2. Molecular formula: C14H22N4O2. Mole weight: 278.36. Catalog: APB1206248852.
Palbociclib Impurity 36
Palbociclib Impurity 36. Uses: For analytical and research use. Alternative Names: tert-butyl 4-(2-aminopyridin-3-yl)piperazine-1-carboxylate. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35. Catalog: APB1023594491.
Palbociclib Impurity 37
Palbociclib Impurity 37. Uses: For analytical and research use. CAS No. 571189-23-6. Molecular formula: C14H22N4O2. Mole weight: 278.36. Catalog: APB571189236.
Palbociclib Impurity 38
Palbociclib Impurity 38. Uses: For analytical and research use. CAS No. 6163-63-9. Molecular formula: C21H21OP. Mole weight: 320.37. Catalog: APB6163639.
Palbociclib Impurity 39
Palbociclib Impurity 39. Uses: For analytical and research use. CAS No. 2242625-36-9. Molecular formula: C13H16ClN3O2. Mole weight: 281.74. Catalog: APB2242625369.
Palbociclib Impurity 4
An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Alternative Names: Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-(1-hydroxyethyl)-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-. Grades: > 95%. CAS No. 1376615-91-6. Molecular formula: C24H31N7O2. Mole weight: 449.56.
Palbociclib Impurity 40
Palbociclib Impurity 40. Uses: For analytical and research use. CAS No. 1974279-20-3. Molecular formula: C26H31N7O3. Mole weight: 489.58. Catalog: APB1974279203.
Palbociclib Impurity 41
Palbociclib Impurity 41. Uses: For analytical and research use. Molecular formula: C34H40F3N9O6S. Mole weight: 759.81. Catalog: APB09493.
Palbociclib Impurity 42
Palbociclib Impurity 42. Uses: For analytical and research use. CAS No. 851067-56-6. Molecular formula: C22H26BrN7O. Mole weight: 484.4. Catalog: APB851067566.
Palbociclib Impurity 43
Palbociclib Impurity 43. Uses: For analytical and research use. CAS No. 2204442-50-0. Molecular formula: C24H29N7O2. Mole weight: 447.54. Catalog: APB2204442500.
Palbociclib Impurity 44
Palbociclib Impurity 44. Uses: For analytical and research use. Molecular formula: C13H13BrClN3O. Mole weight: 342.62. Catalog: APB09494.
Palbociclib Impurity 45
Palbociclib Impurity 45. Uses: For analytical and research use. CAS No. 1941177-45-2. Molecular formula: C29H37N7O3. Mole weight: 531.66. Catalog: APB1941177452.
Palbociclib Impurity 45
Palbociclib Impurity 45. Uses: For analytical and research use. Alternative Names: 6-acetyl-2-((5-((2-aminoethyl)(2-hydroxyethyl)amino)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Molecular formula: C24H31N7O3. Mole weight: 465.55. Catalog: APB01957.
Palbociclib Impurity 5
Palbociclib Impurity 5. Uses: For analytical and research use. CAS No. 2098673-44-8. Molecular formula: C24H30ClN7O3. Mole weight: 500. Catalog: APB2098673448.
Palbociclib Impurity 50
Palbociclib Impurity 50. Uses: For analytical and research use. Alternative Names: tert-butyl 4-(2-nitropyridin-4-yl)piperazine-1-carboxylate. Molecular formula: C14H20N4O4. Mole weight: 308.33. Catalog: APB01406.
Palbociclib Impurity 52
Palbociclib Impurity 52. Uses: For analytical and research use. Alternative Names: 1-(2-nitropyridin-4-yl)piperazine. Molecular formula: C9H12N4O2. Mole weight: 208.22. Catalog: APB01404.
Palbociclib Impurity 6
Palbociclib Impurity 6. Uses: For analytical and research use. CAS No. 153747-97-8. Molecular formula: C14H20BrN3O2. Mole weight: 342.23. Catalog: APB153747978.