A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Haloperidol Metabolite II. Group: Biochemicals. Alternative Names: 4-(4-Chlorophenyl)-α-(4-fluorophenyl)-4-hydroxy-1-piperidinebutanol; R 2572. Grades: Highly Purified. CAS No. 34104-67-1. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Reduced Haloperidol
Reduced haloperidol is an active metabolite of haloperidol. It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. Category: Active pharmaceutical ingredients. CAS No. 34104-67-1. Product ID: API34104671. Molecular formula: C21H25ClFNO2. Mole weight: 377.88.
Reduced Haloperidol-d4
Labeled Haloperidol Metabolite II. Group: Biochemicals. Alternative Names: 4-(4-Chlorophenyl)-α-(4-fluorophenyl)-4-hydroxy-1-piperidinebutanol-d4; R 2572-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Reducing-end cellobiohydrolase 48A from Clostridium stercorarium, Recombinant
Cellulose 1,4-beta-cellobiosidase (reducing end) (EC 3.2.1.176, CelS, CelSS, endoglucanase SS, cellulase SS, cellobiohydrolase CelS, Cel48A) is an enzyme with systematic name 4-beta-D-glucan cellobiohydrolase (reducing end). This enzyme catalyses the following chemical reaction: Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and similar substrates, releasing cellobiose from the reducing ends of the chains. The CelS enzyme from Clostridium thermocellum is the most abundant subunit of the cellulosome formed by the organism. Group: Enzymes. Synonyms: Cellulose 1,4-beta-cellobiosidase (reducing end); EC 3.2.1.176; CelS; CelSS; endoglucanase SS; cellulase SS; cellobiohydrolas. Enzyme Commission Number: EC 3.2.1.176. Purity: >50% by SDS-PAGE. Cellulose 1,4-beta-cellobiosidase. Mole weight: 73.5 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Clostridium stercorarium. Cellulose 1,4-beta-cellobiosidase (reducing end); EC 3.2.1.176; CelS; CelSS; endoglucanase SS; cellulase SS; cellobiohydrolase CelS; Cel48A; 4-beta-D-glucan cellobiohydrolase (reducing end); Reducing-end cellobiohydrolase 48A. Cat No: NATE-1326.
Reductic acid
Reductic acid. Group: Biochemicals. Alternative Names: 2-Cyclopenten-2,3-diol-1-on. Grades: Highly Purified. CAS No. 80-72-8. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Reductiline
Reductiline is a pyrrole derivative produced by Streptomyces orientalis Y-1336. It has anti-Gram-positive bacteria and weak anti-fungal, virus and tumor activity. Synonyms: 2-Propenamide, N-(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-3-[1-[3-(methylthio)propyl]-1H-pyrrol-3-yl]-, (E)-; Antibiotic AIS 2M3. CAS No. 85145-25-1. Molecular formula: C16H20N2O3S. Mole weight: 320.41.
Reductiomycin
Reductiomycin is produced by the strain of Str. griseorubiginosus S551. It can resist gram-positive bacteria, fungi and some yeast. It also inhibits the proliferation of chicken Newcastle disease virus. Synonyms: AM 6201; Alkaloid AM 6201; Antibiotic S 551II; Antibiotic AM 6201; BRN 4525860; (E)-4-(3-((2-hydroxy-5-oxocyclopent-1-en-1-yl)amino)-3-oxoprop-1-en-1-yl)-2,3-dihydrofuran-2-yl acetate. CAS No. 68748-55-0. Molecular formula: C14H15NO6. Mole weight: 293.27.
Reductiomycin
Antibiotic, antibacterial, antifungal and antiviral. Antitumor compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 68748-55-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Redwine Extract
Redwine Extract. Applications: Make skin more white,moist and elastic. Group: Others. Synonyms: Redwine Extract; Vitis vinifera. Purity: 4-10:1, 5%-20% Total Polyphenol. Appearance: Purple brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Fruit. Species: Vitis vinifera. Redwine Extract; Vitis vinifera; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-194.
Red Wine P.E. 50% Polyphenols UV
Red Wine P.E. 50% Polyphenols UV.
CA, FL & NJ
Red yeast rice extract (Ratio)
Red yeast rice extract (Ratio). Group: Others. Purity: 4:1~20:1. Red yeast rice extract (Ratio). Cat No: EXTW-047.
Refametinib
Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 869766; RDEA119. CAS No. 923032-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14691.
Refametinib Impurity 1
Refametinib Impurity 1. Uses: For analytical and research use. CAS No. 923032-38-6. Molecular formula: C19H20F3IN2O5S. Mole weight: 572.34. Catalog: APB923032386.
Refametinib Impurity 2
Refametinib Impurity 2. Uses: For analytical and research use. CAS No. 923032-36-4. Molecular formula: C19H20F3IN2O5S. Mole weight: 572.34. Catalog: APB923032364.
Refametinib Impurity 3
Refametinib Impurity 3. Uses: For analytical and research use. CAS No. 923032-45-5. Molecular formula: C21H24F3IN2O6S. Mole weight: 616.39. Catalog: APB923032455.
Refametinib Impurity 4
Refametinib Impurity 4. Uses: For analytical and research use. CAS No. 1262760-10-0. Molecular formula: C22H24F3IN2O5S. Mole weight: 612.4. Catalog: APB1262760100.
Refametinib Impurity 5
Refametinib Impurity 5. Uses: For analytical and research use. CAS No. 1262760-18-8. Molecular formula: C22H24F3IN2O5S. Mole weight: 612.4. Catalog: APB1262760188.
Refametinib Impurity 6
Refametinib Impurity 6. Uses: For analytical and research use. CAS No. 1311401-03-2. Molecular formula: C20H18F3IN2O5S. Mole weight: 582.33. Catalog: APB1311401032.
Refametinib Impurity 7
Refametinib Impurity 7. Uses: For analytical and research use. CAS No. 1415582-04-5. Molecular formula: C20H18F3IN2O5S. Mole weight: 582.33. Catalog: APB1415582045.
Refanezumab
Refanezumab (GSK249320) is a brain-penetrant IgG1-type humanized monoclonal antibody directed against myelin-associated glycoprotein (MAG). Refanezumab binds to MAG and blocks MAG-mediated inhibition of axonal regeneration. Refanezumab has the potential for the enhancement of recovery of function poststroke[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: GSK249320. CAS No. 1233953-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99403.
Reference Kit for Hydrogen Storage
Reference Kit for Hydrogen Storage.
Refined coconut oil
Refined coconut oil. Alternative Names: Coconut oil. CAS No. 8001-31-8. Product ID: CI-EO-0059. Alfa Chemistry - ISO 9001:32057 Certified.
Regadenoson. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 313348-27-5. Molecular formula: C15H18N8O5. Mole weight: 390.35. Catalog: APB313348275.
Regadenoson
Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CVT-3146. CAS No. 313348-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0168.
Regadenoson-d3
A selective A2A adenosine receptor agonist in myocardial imaging. Group: Biochemicals. Alternative Names: 2-[4-[ (Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Regadenoson-[d3]
Labelled Regadenoson. Regadenoson, as a coronary vasodilator, is a selective A2A adenosine receptor agonist in myocardial imaging. Synonyms: 2-[4-[(Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine-d3; 1-{6-amino-9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-2-yl}-N-(D3)methyl-1H-pyrazole-4-carboxamide; 2-[4-[(Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine D3. Grade: 98%; 99% atom D. Molecular formula: C15H15D3N8O5. Mole weight: 393.37.
Regadenoson Impurity 1
Regadenoson Impurity 1. Uses: For analytical and research use. Alternative Names: methyl 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. CAS No. 1423073-21-5. Molecular formula: C15H17N7O6. Mole weight: 391.34. Catalog: APB1423073215.
Regadenoson Impurity 11
Regadenoson Impurity 11. Uses: For analytical and research use. Alternative Names: 1-(2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-N-methyl-1H-pyrazole-4-carboxamide. Molecular formula: C15H18N8O5. Mole weight: 390.35. Catalog: APB02206.
Regadenoson Impurity 12
Regadenoson Impurity 12. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-(1H-pyrazol-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 1627202-38-3. Molecular formula: C13H15N7O4. Mole weight: 333.3. Catalog: APB1627202383.
Regadenoson Impurity 13
Regadenoson Impurity 13. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-amino-2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate. CAS No. 79999-39-6. Molecular formula: C16H18ClN5O7. Mole weight: 427.8. Catalog: APB79999396.
Regadenoson Impurity 14
Regadenoson Impurity 14. Uses: For analytical and research use. Alternative Names: (E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one. CAS No. 83124-74-7. Molecular formula: C6H7Cl3O2. Mole weight: 217.48. Catalog: APB83124747.
Regadenoson Impurity 15
Regadenoson Impurity 15. Uses: For analytical and research use. Alternative Names: ethyl 3,3-diethoxypropanoate. CAS No. 10601-80-6. Molecular formula: C9H18O4. Mole weight: 190.24. Catalog: APB10601806.
Regadenoson Impurity 17
Regadenoson Impurity 17. Uses: For analytical and research use. Alternative Names: 6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one. CAS No. 1818-71-9. Molecular formula: C10H13N5O5. Mole weight: 283.24. Catalog: APB1818719.
Regadenoson Impurity 18
Regadenoson Impurity 18. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(2,6-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 2096-10-8. Molecular formula: C10H14N6O4. Mole weight: 282.26. Catalog: APB2096108.
Regadenoson Impurity 19
Regadenoson Impurity 19. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-hydrazinyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 15763-11-8. Molecular formula: C10H15N7O4. Mole weight: 297.27. Catalog: APB15763118.
Regadenoson Impurity 2
Regadenoson Impurity 2. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N,N-dimethyl-1H-pyrazole-4-carboxamide. CAS No. 313348-31-1. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB313348311.
Regadenoson Impurity 20
Regadenoson Impurity 20. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N-ethyl-1H-pyrazole-4-carboxamide. CAS No. 313348-33-3. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB313348333.
Regadenoson Impurity 21
Regadenoson Impurity 21. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 1702334-23-3. Molecular formula: C10H10N8O. Mole weight: 258.24. Catalog: APB1702334233.
Regadenoson Impurity 22
Regadenoson Impurity 22. Uses: For analytical and research use. Alternative Names: 1-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 765299-55-6. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB765299556.
Regadenoson Impurity 26
Regadenoson Impurity 26. Uses: For analytical and research use. Alternative Names: methyl 1-(6-amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. Molecular formula: C10H9N7O2. Mole weight: 259.22. Catalog: APB02205.
Regadenoson Impurity 27
Regadenoson Impurity 27. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(6-acetamido-2-chloro-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate. Molecular formula: C18H20ClN5O8. Mole weight: 469.83. Catalog: APB01768.
Regadenoson Impurity 3
Regadenoson Impurity 3. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylic acid. CAS No. 313348-29-7. Molecular formula: C14H15N7O6. Mole weight: 377.31. Catalog: APB313348297.
Regadenoson Impurity 5
Regadenoson Impurity 5. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 146-77-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB146770.
Regadenoson Impurity 6
Regadenoson Impurity 6. Uses: For analytical and research use. Alternative Names: ethyl 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. CAS No. 313348-16-2. Molecular formula: C16H19N7O6. Mole weight: 405.37. Catalog: APB313348162.
Regadenoson Impurity 7
Regadenoson Impurity 7. Uses: For analytical and research use. Alternative Names: ethyl 1H-pyrazole-4-carboxylate. CAS No. 37622-90-5. Molecular formula: C6H8N2O2. Mole weight: 140.14. Catalog: APB37622905.
Regadenoson Impurity 8
Regadenoson Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB01769.
Regadenoson Impurity 9
Regadenoson Impurity 9. Uses: For analytical and research use. Alternative Names: ethyl 2-formyl-3-oxopropanoate. CAS No. 80370-42-9. Molecular formula: C6H8O4. Mole weight: 144.13. Catalog: APB80370429.
Regardsone impurity 1
Regardsone impurity 1. Uses: For analytical and research use. CAS No. 2015222-31-6. Molecular formula: C15H18N8O5. Mole weight: 390.36. Catalog: APB2015222316.
Regardsone impurity 10
Regardsone impurity 10. Uses: For analytical and research use. CAS No. 2015222-35-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB2015222350.
Regardsone impurity 11
Regardsone impurity 11. Uses: For analytical and research use. CAS No. 765299-56-7. Molecular formula: C17H22N8O5. Mole weight: 418.41. Catalog: APB765299567.
Regardsone impurity 12
Regardsone impurity 12. Uses: For analytical and research use. Molecular formula: C18H24N8O5. Mole weight: 432.44. Catalog: APB11350.
Regardsone impurity 15
Regardsone impurity 15. Uses: For analytical and research use. CAS No. 24723-77-1. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB24723771.
Regardsone impurity 20
Regardsone impurity 20. Uses: For analytical and research use. CAS No. 650-51-1. Molecular formula: C2Cl3NaO2. Mole weight: 185.36. Catalog: APB650511.
Regardsone impurity 25
Regardsone impurity 25. Uses: For analytical and research use. CAS No. 2156-56-1. Molecular formula: C2HCl2NaO2. Mole weight: 150.92. Catalog: APB2156561.
Regardsone impurity 26
Regardsone impurity 26. Uses: For analytical and research use. CAS No. 1154383-52-4. Molecular formula: C5H7N3O. Mole weight: 125.13. Catalog: APB1154383524.
Regorafenib
Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. Grade: >98%. CAS No. 755037-03-7. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83.
Regorafenib
Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity. Category: Active pharmaceutical ingredients. CAS No. 755037-03-7. Product ID: API755037037. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82.
Regorafenib
Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331.
Regorafenib
Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-2-pyridinecarboxamide; 4-[4-[N- (4-Chloro-3-trifluoromethylphenyl) ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga. Grades: Highly Purified. CAS No. 755037-03-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 482.82. US Biological Life Sciences.
Worldwide
Regorafenib-[13C,d3]
An isotope labelled Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-13C-d3)-2-pyridinecarboxamide. Grade: ≥99%. CAS No. 2126178-55-8. Molecular formula: C20[13C]H12D3ClF4N4O3. Mole weight: 486.83.
Regorafenib-[13C,d3] N-Oxide
An isotope labelled metabolite of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-2-[(13C,D3)methylcarbamoyl]pyridin-1-ium-1-olate. Grade: 95% by HPLC; 98% atom D; 98% atom 13C. Molecular formula: C20[13C]H12D3ClF4N4O4. Mole weight: 502.83.
Regorafenib (BAY 73-4506)
Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy. Group: Inhibitors. Alternative Names: Fluoro-Sorafenib, BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 5mg. Product ID: S1178. Formula: C21H15ClF4N4O3. Smiles: CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Regorafenib-d3
Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase. Category: Active pharmaceutical ingredients. CAS No. 1255386-16-3. Product ID: API1255386163. Molecular formula: C21H15ClF4N4O3. Mole weight: 485.83.
Regorafenib-[d3]
Regorafenib-[d3] is the labelled analogue of Regorafenib. Regorafenib is an oral kinase inhibitor with an anti-angiogenic activity. Synonyms: Regorafenib D3; 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-d3)-2-pyridinecarboxamide. Grade: 98% HPLC. CAS No. 1255386-16-3. Molecular formula: C21H12D3ClF4N4O3. Mole weight: 485.83.
Regorafenib EP Impurity A
Regorafenib EP Impurity A. Uses: For analytical and research use. CAS No. 757251-39-1. Molecular formula: C13H12FN3O2. Mole weight: 261.26. Catalog: APB757251391.