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| Product | Description | |
|---|---|---|
| Regadenoson Impurity 22 | Regadenoson Impurity 22. Uses: For analytical and research use. Alternative Names: 1-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 765299-55-6. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB765299556. |  |
| Regadenoson Impurity 26 | Regadenoson Impurity 26. Uses: For analytical and research use. Alternative Names: methyl 1-(6-amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. Molecular formula: C10H9N7O2. Mole weight: 259.22. Catalog: APB02205. | |
| Regadenoson Impurity 27 | Regadenoson Impurity 27. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(6-acetamido-2-chloro-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate. Molecular formula: C18H20ClN5O8. Mole weight: 469.83. Catalog: APB01768. | |
| Regadenoson Impurity 3 | Regadenoson Impurity 3. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylic acid. CAS No. 313348-29-7. Molecular formula: C14H15N7O6. Mole weight: 377.31. Catalog: APB313348297. | |
| Regadenoson Impurity 5 | Regadenoson Impurity 5. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 146-77-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB146770. | |
| Regadenoson Impurity 6 | Regadenoson Impurity 6. Uses: For analytical and research use. Alternative Names: ethyl 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. CAS No. 313348-16-2. Molecular formula: C16H19N7O6. Mole weight: 405.37. Catalog: APB313348162. | |
| Regadenoson Impurity 7 | Regadenoson Impurity 7. Uses: For analytical and research use. Alternative Names: ethyl 1H-pyrazole-4-carboxylate. CAS No. 37622-90-5. Molecular formula: C6H8N2O2. Mole weight: 140.14. Catalog: APB37622905. | |
| Regadenoson Impurity 8 | Regadenoson Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB01769. | |
| Regadenoson Impurity 9 | Regadenoson Impurity 9. Uses: For analytical and research use. Alternative Names: ethyl 2-formyl-3-oxopropanoate. CAS No. 80370-42-9. Molecular formula: C6H8O4. Mole weight: 144.13. Catalog: APB80370429. | |
| Regardsone impurity 1 | Regardsone impurity 1. Uses: For analytical and research use. CAS No. 2015222-31-6. Molecular formula: C15H18N8O5. Mole weight: 390.36. Catalog: APB2015222316. | |
| Regardsone impurity 10 | Regardsone impurity 10. Uses: For analytical and research use. CAS No. 2015222-35-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB2015222350. | |
| Regardsone impurity 11 | Regardsone impurity 11. Uses: For analytical and research use. CAS No. 765299-56-7. Molecular formula: C17H22N8O5. Mole weight: 418.41. Catalog: APB765299567. | |
| Regardsone impurity 12 | Regardsone impurity 12. Uses: For analytical and research use. Molecular formula: C18H24N8O5. Mole weight: 432.44. Catalog: APB11350. | |
| Regardsone impurity 15 | Regardsone impurity 15. Uses: For analytical and research use. CAS No. 24723-77-1. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB24723771. | |
| Regardsone impurity 20 | Regardsone impurity 20. Uses: For analytical and research use. CAS No. 650-51-1. Molecular formula: C2Cl3NaO2. Mole weight: 185.36. Catalog: APB650511. | |
| Regardsone impurity 25 | Regardsone impurity 25. Uses: For analytical and research use. CAS No. 2156-56-1. Molecular formula: C2HCl2NaO2. Mole weight: 150.92. Catalog: APB2156561. | |
| Regardsone impurity 26 | Regardsone impurity 26. Uses: For analytical and research use. CAS No. 1154383-52-4. Molecular formula: C5H7N3O. Mole weight: 125.13. Catalog: APB1154383524. | |
| Regorafenib | Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331. |  |
| Regorafenib | Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Synonyms: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. Grade: >98%. CAS No. 755037-03-7. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. |  |
| Regorafenib | Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity. Category: Active pharmaceutical ingredients. CAS No. 755037-03-7. Product ID: API755037037. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82. |  |
| Regorafenib | Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-2-pyridinecarboxamide; 4-[4-[N- (4-Chloro-3-trifluoromethylphenyl) ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga. Grades: Highly Purified. CAS No. 755037-03-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 482.82. US Biological Life Sciences. |  Worldwide |
| Regorafenib-[13C,d3] | An isotope labelled Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-13C-d3)-2-pyridinecarboxamide. Grade: ≥99%. CAS No. 2126178-55-8. Molecular formula: C20[13C]H12D3ClF4N4O3. Mole weight: 486.83. | |
| Regorafenib-[13C,d3] N-Oxide | An isotope labelled metabolite of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-2-[(13C,D3)methylcarbamoyl]pyridin-1-ium-1-olate. Grade: 95% by HPLC; 98% atom D; 98% atom 13C. Molecular formula: C20[13C]H12D3ClF4N4O4. Mole weight: 502.83. | |
| Regorafenib (BAY 73-4506) | Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy. Group: Inhibitors. Alternative Names: Fluoro-Sorafenib, BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 5mg. Product ID: S1178. Formula: C21H15ClF4N4O3. Smiles: CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Regorafenib-d3 | Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase. Category: Active pharmaceutical ingredients. CAS No. 1255386-16-3. Product ID: API1255386163. Molecular formula: C21H15ClF4N4O3. Mole weight: 485.83. | |
| Regorafenib-[d3] | Regorafenib-[d3] is the labelled analogue of Regorafenib. Regorafenib is an oral kinase inhibitor with an anti-angiogenic activity. Synonyms: Regorafenib D3; 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-(methyl-d3)-2-pyridinecarboxamide. Grade: 98% HPLC. CAS No. 1255386-16-3. Molecular formula: C21H12D3ClF4N4O3. Mole weight: 485.83. | |
| Regorafenib EP Impurity A | Regorafenib EP Impurity A. Uses: For analytical and research use. CAS No. 757251-39-1. Molecular formula: C13H12FN3O2. Mole weight: 261.26. Catalog: APB757251391. | |
| Regorafenib EP Impurity B | Regorafenib EP Impurity B. Uses: For analytical and research use. CAS No. 2141961-84-2. Molecular formula: C15H14FN3O3. Mole weight: 303.29. Catalog: APB2141961842. | |
| Regorafenib EP Impurity D | Regorafenib EP Impurity D. Uses: For analytical and research use. CAS No. 2438857-80-6. Molecular formula: C27H22F2N6O5. Mole weight: 548.51. Catalog: APB2438857806. | |
| Regorafenib Hydrochloride | Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506 hydrochloride. CAS No. 835621-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13308. | |
| Regorafenib Hydrochloride | Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Category: Active pharmaceutical ingredients. Synonyms: BAY73-4506 hydrochloride. CAS No. 835621-07-3. Product ID: API835621073. Molecular formula: C21H16Cl2F4N4O3. Mole weight: 519.28. | |
| Regorafenib Impurity 10 | Regorafenib Impurity 10. Uses: For analytical and research use. CAS No. 2098799-12-1. Molecular formula: C19H17FN4O3. Mole weight: 368.37. Catalog: APB2098799121. | |
| Regorafenib Impurity 13 | Regorafenib Impurity 13. Uses: For analytical and research use. CAS No. 2909-32-2. Molecular formula: C14H14N2O. Mole weight: 226.28. Catalog: APB2909322. | |
| Regorafenib Impurity 14 | Regorafenib Impurity 14. Uses: For analytical and research use. CAS No. 835621-12-0. Molecular formula: C20H13ClF4N4O4. Mole weight: 484.79. Catalog: APB835621120. | |
| Regorafenib Impurity 15 | Regorafenib Impurity 15. Uses: For analytical and research use. CAS No. 1343498-72-5. Molecular formula: C20H13ClF4N4O3. Mole weight: 468.79. Catalog: APB1343498725. | |
| Regorafenib Impurity 16 | Regorafenib Impurity 16. Uses: For analytical and research use. CAS No. 1343498-71-4. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82. Catalog: APB1343498714. | |
| Regorafenib Impurity 17 | Regorafenib Impurity 17. Uses: For analytical and research use. CAS No. 2545933-24-0. Molecular formula: C25H22FN5O4. Mole weight: 475.48. Catalog: APB2545933240. | |
| Regorafenib Impurity 17 | Regorafenib Impurity 17. Uses: For analytical and research use. Alternative Names: 4-chloro-3-(trifluoromethyl)aniline. Molecular formula: C7H5ClF3N. Mole weight: 195.57. Catalog: APB01772. | |
| Regorafenib Impurity 18 (Sorafenib Impurity 8) | Regorafenib Impurity 18 (Sorafenib Impurity 8). Uses: For analytical and research use. CAS No. 1379324-09-0. Molecular formula: C7H6Cl2N2O. Mole weight: 205.04. Catalog: APB1379324090. | |
| Regorafenib Impurity 2 | Regorafenib Impurity 2. Uses: For analytical and research use. Molecular formula: C16H16FN3O3. Mole weight: 317.32. Catalog: APB09412. | |
| Regorafenib Impurity 20 | Regorafenib Impurity 20. Uses: For analytical and research use. CAS No. 370-50-3. Molecular formula: C15H8Cl2F6N2O. Mole weight: 417.13. Catalog: APB370503. | |
| Regorafenib Impurity 21 | Regorafenib Impurity 21. Uses: For analytical and research use. CAS No. 9448-54-5. Molecular formula: C9H7ClF3NO2. Mole weight: 253.61. Catalog: APB9448545. | |
| Regorafenib Impurity 27 | Regorafenib Impurity 27. Uses: For analytical and research use. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68. Catalog: APB1333390569. | |
| Regorafenib Impurity 29 | Regorafenib Impurity 29. Uses: For analytical and research use. CAS No. 352277-93-1. Molecular formula: C12H13ClF3NO2. Mole weight: 295.69. Catalog: APB352277931. | |
| Regorafenib Impurity 30 (Sorafenib Impurity 12) | Regorafenib Impurity 30 (Sorafenib Impurity 12). Uses: For analytical and research use. CAS No. 1153328-25-6. Molecular formula: C13H13N3O2. Mole weight: 243.26. Catalog: APB1153328256. | |
| Regorafenib Impurity 50 | Regorafenib Impurity 50. Uses: For analytical and research use. CAS No. 6636-55-1. Molecular formula: C7H6ClNO2. Mole weight: 171.58. Catalog: APB6636551. | |
| Regorafenib Impurity 52 | Regorafenib Impurity 52. Uses: For analytical and research use. Molecular formula: C20H19N5O4. Mole weight: 393.4. Catalog: APB09414. | |
| Regorafenib Impurity 53 | Regorafenib Impurity 53. Uses: For analytical and research use. Molecular formula: C13H12FN3O2. Mole weight: 261.26. Catalog: APB09413. | |
| Regorafenib Impurity 54 | Regorafenib Impurity 54. Uses: For analytical and research use. Molecular formula: C12H11FN2O2. Mole weight: 234.23. Catalog: APB09416. | |
| Regorafenib Impurity 55 | Regorafenib Impurity 55. Uses: For analytical and research use. Molecular formula: C25H19F2N5O4. Mole weight: 491.45. Catalog: APB09417. | |
| Regorafenib Impurity 56 | Regorafenib Impurity 56. Uses: For analytical and research use. Molecular formula: C2613CH20D3ClF4N4O9. Mole weight: 662.95. Catalog: APB09415. | |
| Regorafenib Impurity 57 | Regorafenib Impurity 57. Uses: For analytical and research use. Molecular formula: C27H23ClF4N4O10. Mole weight: 674.94. Catalog: APB09419. | |
| Regorafenib Impurity 58 | Regorafenib Impurity 58. Uses: For analytical and research use. CAS No. 2126178-55-8. Molecular formula: C2013CH12D3ClF4N4O3. Mole weight: 486.83. Catalog: APB2126178558. | |
| Regorafenib Impurity 59 | Regorafenib Impurity 59. Uses: For analytical and research use. Molecular formula: C27H23ClF4N4O9. Mole weight: 658.94. Catalog: APB09418. | |
| Regorafenib Impurity 6 | Regorafenib Impurity 6. Uses: For analytical and research use. CAS No. 1187945-05-6. Molecular formula: C20H12ClF4N3O4. Mole weight: 469.78. Catalog: APB1187945056. | |
| Regorafenib Impurity 60 | Regorafenib Impurity 60. Uses: For analytical and research use. CAS No. 2232228-54-3. Molecular formula: C27H23ClF4N4O9. Mole weight: 658.94. Catalog: APB2232228543. | |
| Regorafenib Impurity 61 | Regorafenib Impurity 61. Uses: For analytical and research use. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82. Catalog: APB09420. | |
| Regorafenib Impurity 62 | Regorafenib Impurity 62. Uses: For analytical and research use. CAS No. 1855006-12-0. Molecular formula: C20H18FN5O3. Mole weight: 395.39. Catalog: APB1855006120. | |
| Regorafenib Impurity 63 | Regorafenib Impurity 63. Uses: For analytical and research use. CAS No. 2098799-13-2. Molecular formula: C35H23Cl2F7N6O5. Mole weight: 811.49. Catalog: APB2098799132. | |
| Regorafenib Impurity 64 | Regorafenib Impurity 64. Uses: For analytical and research use. Molecular formula: C27H24FN7O4. Mole weight: 529.53. Catalog: APB09421. | |
| Regorafenib Impurity 65 | Regorafenib Impurity 65. Uses: For analytical and research use. Molecular formula: C49H31Cl3F10N8O7. Mole weight: 1140.17. Catalog: APB09423. | |
| Regorafenib Impurity 66 | Regorafenib Impurity 66. Uses: For analytical and research use. Molecular formula: C16H16FN3O4. Mole weight: 333.32. Catalog: APB09422. | |
| Regorafenib Impurity 67 | Regorafenib Impurity 67. Uses: For analytical and research use. CAS No. 1446410-29-2. Molecular formula: C8H10ClN3O. Mole weight: 199.64. Catalog: APB1446410292. | |
| Regorafenib Impurity 68 | Regorafenib Impurity 68. Uses: For analytical and research use. Molecular formula: C7H5Cl3N2O. Mole weight: 239.48. Catalog: APB09425. | |
| Regorafenib Impurity 69 | Regorafenib Impurity 69. Uses: For analytical and research use. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82. Catalog: APB09424. | |
| Regorafenib Impurity 7 | Regorafenib Impurity 7. Uses: For analytical and research use. CAS No. 835621-11-9. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82. Catalog: APB835621119. | |
| Regorafenib Impurity 70 | Regorafenib Impurity 70. Uses: For analytical and research use. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82. Catalog: APB09428. | |
| Regorafenib Impurity 71 | Regorafenib Impurity 71. Uses: For analytical and research use. Molecular formula: C27H20ClF4N5O4. Mole weight: 589.93. Catalog: APB09427. | |
| Regorafenib Impurity 72 | Regorafenib Impurity 72. Uses: For analytical and research use. Molecular formula: C27H20ClF4N5O4. Mole weight: 589.93. Catalog: APB09426. | |
| Regorafenib Impurity 73 | Regorafenib Impurity 73. Uses: For analytical and research use. Molecular formula: C7H6Cl2N2O. Mole weight: 205.04. Catalog: APB09430. | |
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