American Chemical Suppliers

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Product
Reveromycin C Reveromycin C is a minor analogue of the reveromycin complex isolated from a Streptomyces sp. Published information suggests that reveromycin C exhibits comparable potency to reveromycin A, its butyl homologue. In Microbial Screening Technologies in-house screens Reveromycins C and A had similar biological profiles but Reveromycin C was generally more potent. Group: Biochemicals. Grades: Highly Purified. CAS No. 144860-69-5. Pack Sizes: 250ug. US Biological Life Sciences. USBiological 1
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Reveromycin D Reveromycin D, the isopentyl analogue, is a minor component of the reveromycin complex isolated from a Streptomyces sp. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C. Group: Biochemicals. Grades: Highly Purified. CAS No. 144860-70-8. Pack Sizes: 250ug. US Biological Life Sciences. USBiological 1
Worldwide
Reveromycin D Reveromycin D is a bacterial metabolite isolated from Streptomyces. It inhibits EGF-induced mitotic activity in Balb/MK cells and has pH-dependent antifungal activity against Candida albicans. Grade: >95% by HPLC. CAS No. 144860-70-8. Molecular formula: C37H54O11. Mole weight: 674.82. BOC Sciences 12
Reversan Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBLC4H10. CAS No. 313397-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107643. MedChemExpress MCE
Reversan ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Reversan Reversan represents a new class of nontoxic MRP1 inhibitor, which may be clinically useful for the treatment of neuroblastoma. Group: Biochemicals. Alternative Names: N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: Highly Purified. CAS No. 313397-13-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
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Reverse T3 Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine [1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,5,3-Triiodothyronine. CAS No. 5817-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-W010696. MedChemExpress MCE
Reverse Transcriptase from HIV, Recombinant Chromatographically purified heterodimer composed of 66kDa and 51kDa subunits. Supplied as a solution in 10mM potassium phosphate, pH 7.4, 1mM DTT and 20% glycerol. Primarily for AIDS research purposes; this enzyme has less fidelity than the AMV enzyme in other applications such as the preparation of cDNA from mRNA for cloning purposes. Applications: Hiv reverse transcriptase is used for research on the aids primer. however it can be substituted for amv reverse transcriptase, which is mainly used to transcribe mrna into double stranded cdna, that can be inserted into prokaryotic vectors. the enzyme can also be used with either single stranded dna or rna templates to mak...or labeling the termini of dna fragments with protruding 5' termini. the enzyme can also be used to sequence dnas by the dideoxy chain termination method of sanger when the klenow fragment of e. coli dna polymerase i, or the t7 dna polymerase yield unsatisfactory results. Group: Enzymes. Synonyms: Reverse transcriptase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. Purity: Chromatographically purified. RT. Mole weight: 66 kDa and 51 kDa. Activity: > 5,000 units per mg protein. Storage: Store at -20°C. Form: A solution in 10mM potassium phosphate, pH 7.4, 1mM DTT and 20% glycerol. Source: E. coli. Species: HIV. Reverse transcriptase; RT. Cat No: NATE-0987. Creative Enzymes
Reverse Transcriptase from Moloney Murine Leukemia Virus, Recombinant This Reverse Transcriptase has exceptionally strong strand displacement activity and enables efficient preparation of cDNA up to 12 kb in length. It is robust, versatile and well-suited for applications requiring full-length cDNA such as preparation of cDNA libraries and other techniques involving first strand cDNA synthesis (RT-PCR, preparation of cDNA probes, real-time quantitative RT-PCR). It can be used for performing a reverse transcription reaction with any RNA template including GC-rich templates and RNAs with high levels of secondary structure. This enzyme is a modified, recombinant MMLV (Moloney Murine Leukemia Virus) reverse transcriptase and is v...ptases tested; 4. highly specific: low rates of non-specific annealing, even on incompletely denatured rna; 5. works on challenging templates: excellent results even with gc-rich templates and templates with high levels of secondary structure 6. highly sensitive: use less of your precious rna samples; 7. demonstrated success with reverse transcription reaction times of 30 min. (60 min. for longer transcripts). Applications: Rt-pcr; first strand cdna synthesis; cdna probe preparation; synthesis of cdna libraries with a high proportion of full-length cdnas. Group: Enzymes. Synonyms: Reverse transcriptase; RT. RT. Storage: Storage at-20°C. Source: E. coli. Spec Creative Enzymes
Reverse transcriptase-IN-1 Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC 50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 III B , E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC 50 of 13.7 nM against HIV-1 reverse transcriptase enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380001-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130241. MedChemExpress MCE
Reversin 121 ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Reversin 205 ?98% (HPLC), film. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Reversine ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Reversine Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC 50 s of 400, 500 and 400 nM for Aurora A , Aurora B and Aurora C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 656820-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14711. MedChemExpress MCE
Reversine (2-(4-Morpholinoanilino)-6-cyclohexylaminopurine) A cell-permeable, potent, and selective human A3 adenosine receptor antagonist (Ki = 0.66uM) and an aurora kinase inhibitor (IC??'s of 30-550 nM for blast colony formation assay). Induces dedifferentiation in murine C2C12 myoblasts. The cells were also shown to regain multipluripotency following removal of the compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 656820-32-5. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 1
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Revised PVOC Mixture certified reference material, 2000 ?g/mL each component in methanol. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Revumenib Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding K i of 0.149 nM and a cell based IC 50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNDX-5613. CAS No. 2169919-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136175. MedChemExpress MCE
Rexamino Rexamino. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,5-Dihydro-4-phenyl-. Product Category: Heterocyclic Organic Compound. CAS No. 52883-35-9. Molecular formula: C9H10N2O. Mole weight: 162.19. Purity: 0.96. IUPACName: 4-phenyl-4,5-dihydro-1,3-oxazol-2-amine. Canonical SMILES: C1C(N=C(O1)N)C2=CC=CC=C2. Density: 1.264g/cm³. Product ID: ACM52883359. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
Reynoutrin Reynoutrin is a flavonoid glycoside isolated from the herbs of Saururus chinensis. Uses: Antioxidant. Synonyms: Quercetin 3-beta-D-xylopyranoside. Grade: 95%. CAS No. 549-32-6. Molecular formula: C20H18O11. Mole weight: 434.35. BOC Sciences 9
Rezafungin Rezafungin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-59-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396640597. Alfa Chemistry Analytical Products 4
Rezafungin Rezafungin, a next-generation, broad-spectrum and long-lasting echinocandin, has potent antifungal activity against Candida spp., Aspergillus spp. and Pneumocystis spp. Synonyms: Biafungin; CD101; SP-3025; 2-{[(2R,6S,9S,11R,12S,14aS,15S,16S,20S,23S,25aS)-23-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6,20-bis[(1R)-1-hydroxyethyl]-16-methyl-5,8,14,19,22,25-hexaoxo-9-({[4''-(pentyloxy)-1,1':4',1''-terphenyl-4-yl]carbonyl}amino)tetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl]oxy}-N,N,N-trimethylethanaminium. Grade: ≥95%. CAS No. 1396640-59-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.39. BOC Sciences
Rezafungin acetate Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp. , Aspergillus spp. , and Pneumocystis spp. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Biafungin acetate; CD101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108009A. MedChemExpress MCE
Rezafungin Impurity 1 Rezafungin Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396639-48-7. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396639487. Alfa Chemistry Analytical Products 4
Rezafungin Impurity 2 Rezafungin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1396640-55-3. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396640553. Alfa Chemistry Analytical Products 4
Rezafungin Impurity 9 Rezafungin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1672717-33-7. Molecular formula: C63H86N9O17+. Mole weight: 1241.43. Catalog: APB1672717337. Alfa Chemistry Analytical Products 4
Rezatapopt Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PC14586. CAS No. 2636846-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156633. MedChemExpress MCE
Rezorstobart Rezorstobart is an anti- KLRB1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2762201-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990760. MedChemExpress MCE
Rezvilutamide Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR3680. CAS No. 1572045-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137448. MedChemExpress MCE
RF9 RF9 is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382. MedChemExpress MCE
RF 9 RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grade: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62. BOC Sciences
RF9 (1-Adamantanecarbonyl-Arg-Phe-NH2) Selective NPFF receptor antagonist (Ki values are 58 and 75nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo. Group: Biochemicals. Alternative Names: 1-Adamantanecarbonyl-Arg-Phe-NH2. Grades: Highly Purified. CAS No. 876310-60-0. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 482.62 free base. US Biological Life Sciences. USBiological 5
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R-Fexofenadine (R-Carboxyterfenadine, R-Terfenadinecarboxyl ate) A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: R-Carboxyterfenadine, R-Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
r-(-)-Flecainide r-(-)-Flecainide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(2R)-2-Piperidinylmethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide; (R)-Flecainide; (-)-Flecainide. Product Category: Heterocyclic Organic Compound. CAS No. 99495-90-6. Molecular formula: C17H20F6N2O3. Mole weight: 414.34. Product ID: ACM99495906. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
R-(-)-Flecainide R-(-)-Flecainide. Group: Biochemicals. Alternative Names: N-[ (2R) -2-Piperidinylmethyl]-2, 5-bis (2, 2, 2-trifluoroethoxy) benzamide; (R)-Flecainide; (-)-Flecainide. Grades: Highly Purified. CAS No. 99495-90-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H20F6N2O3. US Biological Life Sciences. USBiological 7
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R-(?)-Fluoxetine hydrochloride analytical standard. Group: Antidepressants standards. Alfa Chemistry Analytical Products 4
RFP Expressing Glomerular Microvascular Endothelial Cells, Human (Frozen) RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
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RFP Expressing Glomerular Microvascular Endothelial Cells, Human (T-25 flask) RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
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RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (Frozen) Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. USBiological 9
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (T-25 flask) Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. USBiological 9
Worldwide
RFRP-1(human) RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. MedChemExpress MCE
RFRP-2 (rat) RFRP-2 (rat) belongs to the RFamide peptides family, called RFamide-related peptides (RFRPs), which exist in the mammalian brain. Synonyms: Neuropeptide VF Precursor (108-125) amide (rat); H-Ala-Asn-Met-Glu-Ala-Gly-Thr-Met-Ser-His-Phe-Pro-Ser-Leu-Pro-Gln-Arg-Phe-NH2; L-alanyl-L-asparagyl-L-methionyl-L-alpha-glutamyl-L-alanyl-glycyl-L-threonyl-L-methionyl-L-seryl-L-histidyl-L-phenylalanyl-L-prolyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; RFamide-Related Peptide 2 (rat). Grade: 95%. CAS No. 420088-80-8. Molecular formula: C88H134N26O25S2. Mole weight: 2020.29. BOC Sciences
RFRP 3 (human) RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grade: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15. BOC Sciences
RFRP 3 (human) RFRP 3 (human). Group: Biochemicals. Grades: Purified. CAS No. 311309-27-0. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
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RFRP-3(human) RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human). CAS No. 311309-27-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1250. MedChemExpress MCE
RFRP3 (human) acetate RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grade: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19. BOC Sciences
RG100204 RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H2O2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2140901-88-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161834. MedChemExpress MCE
RG108 ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
RG108 RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Phthalyl-L-tryptophan. CAS No. 48208-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13642. MedChemExpress MCE
RG 108 RG 108. Group: Biochemicals. Grades: Purified. CAS No. 48208-26-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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RG 108 (N-Phthalyl-L-tryptophan) A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. Group: Biochemicals. Grades: Highly Purified. CAS No. 48208-26-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
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RG2833 RG2833 is a brain-penetrant HDAC inhibitor with IC50s of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. The Ki values for HDAC1 and HDAC3 are 32 and 5 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RGFP109. CAS No. 1215493-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-16425. MedChemExpress MCE
RG-6080 Nacubactam, also known as RG-6080, FPI-1459, and OP-0595, is a beta-lactamase inhibitor used for treating bacterial infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RG-6080; RG 6080; RG6080; FPI-1459; FPI 1459; FPI1459; OP-0595; OP 0595; OP0595; Nacubactam. Product Category: Inhibitors. Appearance: Off-white to beige solid powder. CAS No. 1452458-86-4. Molecular formula: C9H16N4O7S. Mole weight: 324.31. Purity: >98%. IUPACName: (1R,2S,5R)-2-((2-aminoethoxy)carbamoyl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Canonical SMILES: O=S(O)(ON1[C@]2([H])CC[C@@H](C(NOCCN)=O)[N@@](C2)C1=O)=O. Product ID: ACM1452458864. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
RG7112 RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO5045337. CAS No. 939981-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10959. MedChemExpress MCE
RG7800 RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO6885247. CAS No. 1449598-06-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101792. MedChemExpress MCE
RG7800 tetrahydrochloride RG7800 hydrochloride is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; RG7800 hydrochloride has the potential to treat spinal muscular atrophy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO6885247 tetrahydrochloride. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101792A. MedChemExpress MCE
RG7834 RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 7020322. CAS No. 2072057-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117650A. MedChemExpress MCE
Rga I One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCGAT↑CGC CGC↓TAGCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Rhizoblum galegae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1164RE. Creative Enzymes
R-(γ)-Phe R-(γ)-Phe. Synonyms: R gamma Phe. CAS No. 63328-06-3. Molecular formula: C11H15NO2. Mole weight: 193.24. BOC Sciences 11
RGB-1 RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 930455-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156228. MedChemExpress MCE
RGB-286638 RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3?, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 784210-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15504. MedChemExpress MCE
RGB-286638 free base RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3?, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 784210-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15504A. MedChemExpress MCE
RGB-286638 free base RGB-286638 is a multitargeted cyclin-dependent kinase inhibitor. RGB-286638 triggers P53-dependent and -independent anti-multiple myeloma activity through inhibition of transcriptional CDKs. GB-286638 treatment resulted in MM cytotoxicity in vitro associated with inhibition of MM tumor growth and prolonged survival in vivo. RGB-286638 displayed caspase-dependent apoptosis in both wt-p53 and mutant-p53 cells that was closely associated with the downregulation of RNA polymerase II phosphorylation and inhibition of transcription. RGB-286638 triggered p53 accumulation via nucleolar stress and loss of Mdm2, accompanied by induction of p53 DNA-binding activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RGB-286638, RGB 286638, RGB286638; RGB-286638 free base. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 784210-88-4. Molecular formula: C29H35N7O4. Mole weight: 545.64. Purity: >98%. IUPACName: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea. Canonical SMILES: O=C(NN1CCOCC1)NC2=CC=CC(C3=C4C(C5=CC=C(CN6CCN(CCOC)CC6)C=C5)=NN3)=C2C4=O. Product ID: ACM784210884. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
RGD RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 99896-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0278. MedChemExpress MCE
RGD-4C RGD-4C preferentially binds to integrins αvβ3 and αvβ5, both of which are overexpressed in many cancers, such as non-small cell lung cancer, melanoma, and growing vessels. Synonyms: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); L-alanyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-arginyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-glycine (2->10),(4->8)-bis(disulfide); N-{[(1R,4S,7R,12R,15S,18R,21S,27S)-7-(L-Alanylamino)-15-benzyl-27-(3-carbamimidamidopropyl)-4,21-bis(carboxymethyl)-3,6,14,17,20,23,26,29-octaoxo-9,10,31,32-tetrathia-2,5,13,16,19,22,25,28-octaazabicyclo[16.11.4]tritriacont-12-yl]carbonyl}glycine. Grade: ≥95%. CAS No. 332179-76-7. Molecular formula: C42H60N14O16S4. Mole weight: 1145.29. BOC Sciences 11

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