A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Rezafungin Impurity 11. Uses: For analytical and research use. CAS No. 2649486-80-4. Molecular formula: C65H87N8O17+. Mole weight: 1252.45. Catalog: APB2649486804.
Rezafungin Impurity 12
Rezafungin Impurity 12. Uses: For analytical and research use. CAS No. 2649486-31-5. Molecular formula: C64H85N8O17+. Mole weight: 1238.42. Catalog: APB2649486315.
Rezafungin Impurity 13
Rezafungin Impurity 13. Uses: For analytical and research use. CAS No. 2649486-14-4. Molecular formula: C65H87N8O17+. Mole weight: 1252.45. Catalog: APB2649486144.
Rezafungin Impurity 14
Rezafungin Impurity 14. Uses: For analytical and research use. CAS No. 2649486-23-5. Molecular formula: C66H89N8O17+. Mole weight: 1266.48. Catalog: APB2649486235.
Rezafungin Impurity 15
Rezafungin Impurity 15. Uses: For analytical and research use. CAS No. 2649486-89-3. Molecular formula: C63H82F3N8O17+. Mole weight: 1280.38. Catalog: APB2649486893.
Rezafungin Impurity 2
Rezafungin Impurity 2. Uses: For analytical and research use. CAS No. 1396640-55-3. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB1396640553.
Rezafungin Impurity 3
Rezafungin Impurity 3. Uses: For analytical and research use. CAS No. 2401852-82-0. Molecular formula: C63H85N8O17+. Mole weight: 1226.41. Catalog: APB2401852820.
Rezafungin Impurity 4
Rezafungin Impurity 4. Uses: For analytical and research use. CAS No. 2649486-48-4. Molecular formula: C64H87N8O17+. Mole weight: 1240.44. Catalog: APB2649486484.
Rezafungin Impurity 5
Rezafungin Impurity 5. Uses: For analytical and research use. CAS No. 2649486-50-8. Molecular formula: C64H87N8O17+. Mole weight: 1240.44. Catalog: APB2649486508.
Rezafungin Impurity 6
Rezafungin Impurity 6. Uses: For analytical and research use. CAS No. 2649487-01-2. Molecular formula: C64H87N8O17+. Mole weight: 1240.44. Catalog: APB2649487012.
Rezafungin Impurity 7
Rezafungin Impurity 7. Uses: For analytical and research use. CAS No. 2649486-11-1. Molecular formula: C63H84FN8O17+. Mole weight: 1244.4. Catalog: APB2649486111.
Rezafungin Impurity 8
Rezafungin Impurity 8. Uses: For analytical and research use. CAS No. 2649486-21-3. Molecular formula: C64H85N8O17+. Mole weight: 1238.42. Catalog: APB2649486213.
Rezafungin Impurity 9
Rezafungin Impurity 9. Uses: For analytical and research use. CAS No. 1672717-33-7. Molecular formula: C63H86N9O17+. Mole weight: 1241.43. Catalog: APB1672717337.
Rezatapopt
Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PC14586. CAS No. 2636846-41-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156633.
Rezetamig
Rezetamig is a human bispecific antibody that recognizes the CD3 antigen on T-lymphocytes and the CD22 antigen on mature and malignant B-lymphocytes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JNJ-75348780. CAS No. 2795115-07-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990759.
Rezivertinib
Rezivertinib (BPI-7711) is an orally active, highly selective and irreversible third-generation EGFR tyrosine kinase inhibitor (TKI). Rezivertinib exhibits high potency against the common activation EGFR and the resistance T790M mutations. Rezivertinib has excellent central nervous system (CNS) penetration and has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPI-7711. CAS No. 1835667-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-109189.
Rezorstobart
Rezorstobart is an anti-KLRB1 human IgG1 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: IMT-009. CAS No. 2762201-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990760.
Rezuforimod
Rezuforimod (AGN-232411; AG-80308) is an ophthalmic solution targeting the formyl peptide receptor (FPR) pathway. Rezuforimod exerts anti-inflammatory effects by targeting the formyl peptide receptor pathway. Administered topically, Rezuforimod significantly reduces the corneal conjunctival staining score and improves ocular discomfort symptoms, with no serious adverse events reported and favorable overall safety profile. Rezuforimod shows remarkable potential to serve as a novel therapeutic option for dry eye disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AGN-232411; AG-80308; AGN-411. CAS No. 1431754-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172435.
RF9
RF9 is a potent and selective Neuropeptide FF receptor antagonist, with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382.
RF 9
RF 9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively. It displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Synonyms: 2-Adamantanecarbonyl-Arg-Phe-NH2. Grade: ≥96%. CAS No. 876310-60-0. Molecular formula: C26H38N6O3. Mole weight: 482.62.
RF9 (1-Adamantanecarbonyl-Arg-Phe-NH2)
Selective NPFF receptor antagonist (Ki values are 58 and 75nM at hNPFF1 and hNPFF2 receptors respectively). Displays selectivity over several related receptors including NPY Y1 GPR10, GPR54, GPR103 and the opioid receptors. Blocks NPFF-induced hypothermia and increases in atrial blood pressure and heart rate, and prevents opioid-induced tolerance associated with hyperalgesia in vivo. Group: Biochemicals. Alternative Names: 1-Adamantanecarbonyl-Arg-Phe-NH2. Grades: Highly Purified. CAS No. 876310-60-0. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?, Molecular Weight: 482.62 free base. US Biological Life Sciences.
A metabolite of of terfenadine, a H1-Histamine receptor antagonist. Group: Biochemicals. Alternative Names: R-Carboxyterfenadine, R-Terfenadinecarboxyl ate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
R-(-)-Flecainide
R-(-)-Flecainide is a orally active antiarrhythmic agent that inhibits ventricular ectopic activity. Category: Active pharmaceutical ingredients. CAS No. 99495-90-6. Product ID: API99495906. Molecular formula: C17H20F6N2O3. Mole weight: 414.34.
R-(-)-Flecainide
R-(-)-Flecainide. Group: Biochemicals. Alternative Names: N-[ (2R) -2-Piperidinylmethyl]-2, 5-bis (2, 2, 2-trifluoroethoxy) benzamide; (R)-Flecainide; (-)-Flecainide. Grades: Highly Purified. CAS No. 99495-90-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H20F6N2O3. US Biological Life Sciences.
RFP Expressing Glomerular Microvascular Endothelial Cells, Human (Frozen)
RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Glomerular Microvascular Endothelial Cells, Human (T-25 flask)
RFP-HGMECs were selected from Zeocin resistant HGMECs after transfection with RFP- expressing Lentiviral particles. Cells are shipped in proliferating culture with >90% confluence (cells are provided at passages 3-5). ENDO-Growth medium containing 5% serum and growth supplement are recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Liver Sinusoidal Microvascular Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HLSECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling capacity of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Retinal Microvascular Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HRMECs were selected and shipped in proliferating culture with a confluence of >90% (cells are provided at passage 4-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for cell culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Saphenous Vein Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HSVECs were selected. The cells were shipped in proliferating culture with >90% confluence (cells are provided at passage 3-5). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. These cells have an average population doubling capacity of >16. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (Frozen)
Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
Worldwide
RFP Expressing Umbilical Vein Endothelial Cells, Human (T-25 flask)
Zeocin resistant RFP-HUVECs were selected and shipped in proliferating culture with >90% confluence (cells are provided at passage 3). ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >18. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
Worldwide
RFRP-2 (rat)
RFRP-2 (rat) belongs to the RFamide peptides family, called RFamide-related peptides (RFRPs), which exist in the mammalian brain. Synonyms: Neuropeptide VF Precursor (108-125) amide (rat); H-Ala-Asn-Met-Glu-Ala-Gly-Thr-Met-Ser-His-Phe-Pro-Ser-Leu-Pro-Gln-Arg-Phe-NH2; L-alanyl-L-asparagyl-L-methionyl-L-alpha-glutamyl-L-alanyl-glycyl-L-threonyl-L-methionyl-L-seryl-L-histidyl-L-phenylalanyl-L-prolyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; RFamide-Related Peptide 2 (rat). Grade: 95%. CAS No. 420088-80-8. Molecular formula: C88H134N26O25S2. Mole weight: 2020.29.
RFRP 3 (human)
RFRP-3 (RFamide-related peptide-3), a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP-3 was recently shown to potently inhibit GnRH stimulation of gonadotropin secretion from sheep in vivo and from cultured gonadotropes through inhibition of Ca2+ mobilization. Synonyms: NPVF; Neuropeptide VF (124-131) (human); H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide; Neuropeptide NPVF; RFamide-related peptide 3; L-Val-L-Pro-L-Asn-L-Leu-L-Pro-L-Gln-L-Arg-L-Phe-NH2. Grade: ≥95% by HPLC. CAS No. 311309-27-0. Molecular formula: C45H72N14O10. Mole weight: 969.15.
RFRP 3 (human)
RFRP 3 (human). Group: Biochemicals. Grades: Purified. CAS No. 311309-27-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
RFRP3 (human) acetate
RFRP3 (human) acetate, a homolog of avian gonadotropin-inhibitory hormone, is an agonist of the NPFF1 receptor (IC50 = 0.7 nM for inhibition of forskolin-induced cAMP production). The human RFRP3 can effectively inhibit GNRH-stimulated gonadotropin secretion in sheep in vivo and in culture by inhibiting Ca2+ mobilization. Synonyms: H-Val-Pro-Asn-Leu-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-valyl-L-prolyl-L-asparagyl-L-leucyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid; RFRP-3 acetate; RFRP 3 acetate; RFamide-related peptide-3 acetate. Grade: ≥95%. Molecular formula: C47H76N14O12. Mole weight: 1029.19.
RG100204
RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H2O2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140901-88-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161834.
RG108
RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Phthalyl-L-tryptophan. CAS No. 48208-26-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13642.
RG 108
RG 108. Group: Biochemicals. Grades: Purified. CAS No. 48208-26-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RG 108 (N-Phthalyl-L-tryptophan)
A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294, RG 108 enhances reprogramming. Group: Biochemicals. Grades: Highly Purified. CAS No. 48208-26-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RG2833
RG2833 is a brain-penetrant HDAC inhibitor with IC50s of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. The Ki values for HDAC1 and HDAC3 are 32 and 5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RGFP109. CAS No. 1215493-56-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-16425.
RG3039
RG3039 (PF-06687859) is an orally active, blood-brain barrier-permeable DcpS inhibitor with an IC50 of 4.2 nM against hDcpS. RG3039 inhibits the decapping activity of DcpS and maintains DcpS in a catalytically inactive conformation in the central nervous system and other tissues. RG3039 extends survival and improves function in spinal muscular atrophy mice. RG3039 is applicable to research related to spinal muscular atrophy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06687859. CAS No. 1005504-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102020.
RG7112
RG7112 is a potent, selective, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO5045337. CAS No. 939981-39-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10959.
RG7834
RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO 7020322; (S)-RO0321. CAS No. 2072057-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117650A.
Rga I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GCGAT↑CGC CGC↓TAGCG. Activity: 5000-10000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Rhizoblum galegae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1164RE.
R-(γ)-Phe
R-(γ)-Phe. Synonyms: R gamma Phe. CAS No. 63328-06-3. Molecular formula: C11H15NO2. Mole weight: 193.24.
RGB-286638
RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 784210-87-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15504.
RGD
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins. Uses: Scientific research. Category: Signaling pathways. CAS No. 99896-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0278.
RGD-4C
RGD-4C preferentially binds to integrins αvβ3 and αvβ5, both of which are overexpressed in many cancers, such as non-small cell lung cancer, melanoma, and growing vessels. Synonyms: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); L-alanyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-arginyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-glycine (2->10),(4->8)-bis(disulfide); N-{[(1R,4S,7R,12R,15S,18R,21S,27S)-7-(L-Alanylamino)-15-benzyl-27-(3-carbamimidamidopropyl)-4,21-bis(carboxymethyl)-3,6,14,17,20,23,26,29-octaoxo-9,10,31,32-tetrathia-2,5,13,16,19,22,25,28-octaazabicyclo[16.11.4]tritriacont-12-yl]carbonyl}glycine. Grade: ≥95%. CAS No. 332179-76-7. Molecular formula: C42H60N14O16S4. Mole weight: 1145.29.
RGD Negative Control
It is the negative control of c(RGDfE). Synonyms: c(RADfE); cyclo[Ala-Asp-D-Phe-Glu-Arg]; cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl-L-arginyl]. Grade: ≥95%. CAS No. 756500-24-0. Molecular formula: C27H38N8O9. Mole weight: 618.65.
RGD peptide
RGD peptide is an inhibitor of integrin-ligand interactions. Synonyms: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. Grade: 98%. CAS No. 114681-65-1. Molecular formula: C23H38N10O10. Mole weight: 614.61.
RGD peptide (Arg-Gly-Asp)
RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Group: Inhibitors. CAS No. 99896-85-2. Pack Sizes: 10mg. Product ID: S8008. Formula: C12H22N6O6. Smiles: C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
RGD peptide (GRGDNP)
RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 114681-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1740.
RGD peptide TFA
RGD peptide TFA is an inhibitor of integrin-ligand interactions. Synonyms: RGD peptide (GRGDNP) TFA; H-Gly-Arg-Gly-Asp-Asn-Pro-OH.TFA; glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline trifluoroacetic acid. Grade: ≥98%. Molecular formula: C23H38N10O10.C2HF3O2. Mole weight: 728.63.
RGD-targeted Proapoptotic Peptide
RGD-targeted Proapoptotic Peptide is RGD-4C conjugated to a full D proapoptotic peptide. Synonyms: RGD-4C-GG-(klaklak)2-NH2; H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic(2→10),(4→8)-bis(disulfide). Grade: ≥95%. CAS No. 2243207-09-0. Molecular formula: C116H199N35O31S4. Mole weight: 2708.34.
RGD Trifluoroacetate
It is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Synonyms: H-RGD-OH.TFA; L-arginyl-glycyl-L-aspartic acid trifluoroacetic acid; (S)-2-(2-((S)-2-Amino-5-guanidinopentanamido)acetamido)succinic acid trifluoroacetate. Grade: >98%. CAS No. 120103-89-1. Molecular formula: C12H22N6O6.C2HF3O2. Mole weight: 460.36.
RGFP966
RGFP966 is a highly selective HDAC3 inhibitor with an IC50 of 80 nM and shows no inhibition to other HDACs at concentrations up to 15 μM. RGFP966 can penetrate the blood brain barrier (BBB). Uses: Scientific research. Category: Signaling pathways. CAS No. 1357389-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13909.
RGFP966
RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM in cell-free assay, exhibits > 200-fold selectivity over other HDAC. Group: Inhibitors. CAS No. 1396841-57-8. Pack Sizes: 10mg. Product ID: S7229. Formula: C21H19FN4O. Smiles: C1=CC=C(C=C1)C=CCN2C=C(C=N2)C=CC(=O)NC3=C(C=C(C=C3)F)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
rGHRH(1-29)NH2
A synthetic peptide that stimulates the secretion of growth hormone (GH). Synonyms: GRF (1-29) amide (rat); His-Ala-Asp-Ala-Ile-Phe-Thr-Ser-Ser-Tyr-Arg-Arg-Ile-Leu-Gly-Gln-Leu-Tyr-Ala-Arg-Lys-Leu-Leu-His-Glu-Ile-Met-Asn-Arg-NH2; GRF (1-29)-NH2 Rat. Grade: >98%. Molecular formula: C155H251N49O40S. Mole weight: 3473.02.
RGLS4326
RGLS4326 (RG4326) is a first-in-class, short oligonucleotide inhibitor of microRNA-17 (miR-17). RGLS4326 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 inhibits miR-17 function in HeLa cells with an EC50 value of 28.3 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG4326. CAS No. 2229964-07-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-139290.
RGN6024
RGN6024 is a brain-penetrant, orally active and reversible small molecule tubulin destabilizer. RGN6024 inhibits microtubule polymerization both in biochemical and cellular assays, binds to the colchicine binding pocket of β-tubulin (SPR: Kd = 6.7 μM; tryptophan assay: Kd = 7.4 μM), and triggers G2/M arrest in glioblastoma (GB) cells. RGN6024 retains activity in βIII-tubulin overexpressing cells. RGN6024 inhibits tumor growth in a GB xenograft mouse model. RGN6024 can be used for the study of glioblastoma (GB)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055038-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176537.
rGO-NH-Carboimidazole
rGO-NH-Carboimidazole. CAS No. 7440-44-0. Purity: 99%. Product ID: ACM7440440-240. Alfa Chemistry - ISO 9001:32057 Certified.
RGS Proteins Inhibitor II, CCG-50014 (4-(4-Fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione)
A cell-permeable thiadiazolidinedione compound that acts as a direct, potent, selective and cysteine-reactive irreversible inhibitor of RGS4 over other RGS proteins (IC50=0.03, 0.12, 3.5, 11, >200 and >200uM against RGS4, RGS19, RGS16, RGS8, RGS7 and RGS4Cys- using FCPIA assay, respectively). Shown to block RGS4-Ga0 interaction and repress Ga0-dependent membrane localization of RGS4 in HEK-293T cells with no effect on the intrinsic rate of GTP hydrolysis by Ga0. Suggested to interact with Cys107-RGS8 allosteric regulatory site and display minimal affinity towards papain (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RGT-018
RGT-018 is a potent and orally active SOS1 inhibitor with anti-tumor effects. RGT-018 exerts anti-cancer cell proliferation activity by inhibiting KRAS activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2794934-49-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-163939.
RGX-104
RGX-104 is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Abequolixron. CAS No. 610318-54-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111498A.
RH01386
RH01386 is a small molecule that can prevent endoplasmic reticulum stress (ERS)-induced β cell dysfunction and death, and inhibits proapoptotic gene expression. RH01386 restores ERS-impaired glucose-stimulated insulin secretion responses. RH01386 has the potential for type 2 diabetes treatment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301177-36-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124771.
Rhacophorin-1 antimicrobial peptide precursor
Rhacophorin-1 antimicrobial peptide precursor is an antibacterial peptide isolated from Rhacophorus feae. Synonyms: Ile-Gly-Pro-Met-Ile-Lys-Ile-Ala-Thr-Asn-Leu-Leu-Pro-Thr-Val-Ile-Cys-Lys-Ile-Phe-Lys-Lys-Cys. Grade: >96%.