A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
TPX-0005 is an orally available and potent ATP-competitive inhibitor of ALK/ROS1/TRK (IC50= 5.3 nM for SRC, IC50= 1.01 nM, 1.26 nM and 1.08 nM for mutant ALKs including WT ALK, ALK G1202R and ALK L1196M, respectively). Alternative Names: TPX-0005; TPX 0005; TPX0005. CAS No. 1802220-02-5. Molecular formula: C18H18FN5O2. Mole weight: 355.37.
Repotrectinib
Repotrectinib (TPX-0005) is a potent ROS1 (IC50=0.07 nM) and TRK (IC50=0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK (IC50=1.01 nM). Repotrectinib has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TPX-0005. CAS No. 1802220-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103022.
repressor LexA
RecA protein and single-stranded DNA are required for activity, which is attributed to a Ser/Lys dyad. The LexA protein represses the SOS regulon, which regulates the genes involved in DNA repair. In the presence of single-stranded DNA, the RecA protein interacts with repressor LexA, causing it to undergo an autocatalytic cleavage which disrupts the DNA-binding part of the repressor, and inactivates it. The consequent derepression of the SOS regulon leads to DNA repair. This peptidase activity of LexA was previously attributed to the RecA protein. Type example of peptidase family S24. Group: Enzymes. Synonyms: LexA repressor. Enzyme Commission Number: EC 3.4.21.88. CAS No. 84721-00-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4179; repressor LexA; EC 3.4.21.88; 84721-00-6; LexA repressor. Cat No: EXWM-4179.
Reprogramming Compound Library
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. - Targets include MEK, TGF-β, GSK3, wnt, etc. - Structural diversity, significant pharmaceutical efficacy, and cell permeability. - Detailed instructions, compound structures, target information, IC50 values, activity descriptions, etc. - Various assays such as NMR, HPLC/LCMS to ensure the correct structure and high purity of the product and reduce false positives. Uses: Scientific use. Product Category: L8110. Categories: Reprogramming Compounds Libraries.
Reproterol
Reproterol is a selective β2-adrenoceptor agonist and cAMP phosphodiesterase (PDE) inhibitor. Reproterol inhibits adenylate cyclase-induced phosphodiesterase activity. Reproterol inhibits histamine release from mast cells. Reproterol is applicable to research related to asthma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 54063-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135490.
RepSox
RepSox. Group: Biochemicals. Grades: Purified. CAS No. 446859-33-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RepSox
RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-616452; SJN 2511. CAS No. 446859-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13012.
RepSox (E-616452)
RepSox (E-616452, SJN 2511, ALK5 Inhibitor II) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation in cell-free assays, respectively. Group: Inhibitors. Alternative Names: SJN 2511,ALK5 Inhibitor II. CAS No. 446859-33-2. Pack Sizes: 25mg. Product ID: S7223. Formula: C17H13N5. Smiles: CC1=NC(=CC=C1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4. Storage Conditions: 2 years -80 in solvent.
United States; Europe
RepSox (GMP)
RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-β-RI/ALK5 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E-616452 (GMP); SJN 2511 (GMP). CAS No. 446859-33-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13012G.
Reptilian Defensin
Reptilian Defensin is an antimicrobial peptide found in Caretta caretta, and has antibacterial and antiviral activity. Grades: >98%.
RER1 protein (80-91)
RER1 protein (80-91) is a bioactive peptide of RER1 protein which is involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
RES-1149-1
RES-1149-1 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 1.5 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5.
RES-1149-2
RES-1149-2 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 20 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5.
RES-1214-1
RES-1214-1 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 1.5 μmol/L. Molecular formula: C17H16O8. Mole weight: 348.3.
RES-1214-2
RES-1214-2 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 20 μmol/L. Molecular formula: C17H15ClO8. Mole weight: 382.7.
RES-701-1
RES-701-1 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Uses: Endothelin receptor antagonists. Alternative Names: GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP; GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP). Grades: 95%. CAS No. 151308-34-8. Molecular formula: C103H115N23O23. Mole weight: 2043.16.
RES-701-2
RES-701-2 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Molecular formula: C103H115N23O24. Mole weight: 2059.15.
RESA peptide
RESA peptide is a substrate peptide of β-adrenergic receptor kinase (βARK). RESA peptide serves as a substrate for βARK-mediated phosphorylation, and its N-terminal acidic residues enhance phosphorylation efficiency and substrate binding capacity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 133699-13-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P11765.
Resatorvid
Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-α and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-242; CLI-095. CAS No. 243984-11-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11109.
Resatorvid (TAK-242)
Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy. Group: Inhibitors. Alternative Names: CLI-095. CAS No. 243984-11-4. Pack Sizes: 5mg. Product ID: S7455. Formula: C15H17ClFNO4S. Smiles: CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl. Storage Conditions: 3 years -20°C powder.
United States; Europe
Resazurin
Resazurin is a blue dye used as an oxidation-reduction (redox) indicator in various biochemical and cell viability assays. It is particularly valued for its ability to measure cell metabolic activity. Alternative Names: 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide; 7-Hydroxy-3H-phenoxazin-3-one 10-oxide; 7-Hydroxy-3H-phenoxazine-3-one 10-oxide; Alamar Blue; Azoresorcin; Diazoresorcinol; NSC 10438; NSC 56323; Resazoin; Resazurin assay; Resazurine; Rhodalux. CAS No. 550-82-3. Molecular formula: C12H7NO4. Mole weight: 229.19.
Resazurin sodium
Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diazoresorcinol sodium. CAS No. 62758-13-8. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-111391.
Resazurin Sodium Certified
Resazurin Sodium Certified. Uses: For analytical and research use. CAS No. 62758-13-8. Molecular formula: C12H6NNaO4. Mole weight: 251.17. IUPAC Name: sodium;10-oxido-7-oxophenoxazin-10-ium-3-olate. Catalog: APB62758138.
Resazurin sodium, indicator
Resazurin (Diazoresorcinol) sodium, indicator is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium, indicator is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium, indicator can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diazoresorcinol sodium, indicator. CAS No. 62758-13-8. Pack Sizes: 1 g; 5 g. Product ID: HY-111391A.
Resazurin sodium salt
Resazurin sodium salt. Group: Biochemicals. Alternative Names: 7-Hydroxy-3H-phenoxazin-3-one 10-oxide sodium salt. Grades: Highly Purified. CAS No. 62758-13-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C12H6NO4Na. US Biological Life Sciences.
Worldwide
Resazurin sodium salt
1g Pack Size. Group: Stains & Indicators. Formula: C12H6NNaO4. CAS No. 62758-13-8. Prepack ID 56554686-1g. Molecular Weight 251.17. See USA prepack pricing.
Resazurin sodium salt
Resazurin is a blue non-fluorescent dye that is used as an oxidation-reduction indicator in cell viability assays. Resazurin generates red fluorescence when reduced to resorufin. Alternative Names: 7-hydroxy-3H-phenoxazin-3-one-10-oxide monosodium salt. CAS No. 62758-13-8. Molecular formula: C12H6NNaO4. Mole weight: 251.2.
Resazurin, Sodium Salt
Indicator for sensitive enzyme analysis. Group: Biochemicals. Alternative Names: 7-Hydroxy-3H-phenoxazin-3-one-10-oxide sodium salt. Grades: Molecular Biology Grade. CAS No. 62758-13-8. Pack Sizes: 25g, 100g. Molecular Formula: C12H6NO4Na, Molecular Weight: 251.2. US Biological Life Sciences.
Worldwide
Resazurin sodium salt ≥90% (HPLC)
Resazurin sodium salt ≥90% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
Reserpic Acid Methyl Ester
Reserpine derivative, an alkaloid found in Rauwolfia. Group: Biochemicals. Alternative Names: Methyl reserpate; Methyl reserpinolate; NSC 81464; (3 β,16 β,17α,18 β,20α)-18-Hydroxy-11,17-dimethoxy-yohimban-16-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 2901-66-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Reserpiline
Reserpiline. Group: Biochemicals. Grades: Highly Purified. CAS No. 131-02-2. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Reserpiline
Reserpiline is an indole alkaloid that has been found in R. tetraphylla. It is an antipsychotic, antiparasitic and hypotensive agent. Alternative Names: Methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate; Elliptamine; Reserpilin; (-)-Reserpiline; (4S,4aS,13bR,14aS)-4a,5,7,8,13,13b,14,14a-octahydro-10,11-dimethoxy-4-methyl-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid, methyl ester; methyl (4S,4aS,13bR,14aS)-10,11-dimethoxy-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate. Grades: >95% by HPLC. CAS No. 131-02-2. Molecular formula: C23H28N2O5. Mole weight: 412.48.
Reserpine
Reserpine is an inhibitor of multidrug efflux pumps, used as an antipsychotic and antihypertensive drug. Uses: Antihypertensive. Alternative Names: 3,4,5-TRIMETHOXYBENZOYL METHYL RESERPATE; 11,17-DIMETHOXY-18-[(3,4,5-TRIMETHOXYBENZOYL)OXY]YOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER; METHYL RESERPATE; METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER; l -Carpserp; (3beta,16beta,17alpha,18beta,20alpha)-methyleste; ,methylester,(3beta,16beta,17alpha,18beta,20alpha)-. Grades: >98%. CAS No. 50-55-5. Molecular formula: C33H40N2O9. Mole weight: 608.68.
Reserpine
1g Pack Size. Group: Bioactive Small Molecules, Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Research Organics & Inorganics. Formula: C33H40N2O9. CAS No. 50-55-5. Prepack ID 70515639-1g. Molecular Weight 608.68. See USA prepack pricing.
Reserpine
Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Uses: Scientific research. Category: Induced disease models products. CAS No. 50-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-N0480.
Reserpine
An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 50-55-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Reserpine-d9
Labeled Reserpine. An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 84759-11-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Reserpine (Standard) is the analytical standard of Reserpine. This product is intended for research and analytical applications. Reserpine is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). Uses: Scientific research. Category: Signaling pathways. CAS No. 50-55-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0480R.
Resibufogenin
Resibufogenin. Group: Biochemicals. Grades: Highly Purified. CAS No. 465-39-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C24H32O4. US Biological Life Sciences.
Worldwide
Resibufogenin
Resibufogenin influenced peak amplitude, overshoot and half-width of the evoked single action potential, and simultaneously lessened the firing rate of evoked repetitive firing. Uses: An anti-cancer monomomer. Alternative Names: bufogenin; (3beta,5beta,8xi,9xi,15beta)-3-hydroxy-14,15-epoxybufa-20,22-dienolide; 3-hydroxy-14,15-epoxybufa-20,22-dienolide; (3beta,5beta,15beta)-3-hydroxy-14,15-epoxybufa-20,22-dienolide. Grades: >98%. CAS No. 465-39-4. Molecular formula: C24H32O4. Mole weight: 384.5.
Resibufogenin
Resibufogenin is an orally active anticancer agent. Resibufogenin can be extracted from toad venom. Resibufogenin blocks signaling pathways such as PI3K/Akt, NF-κB, AP-1, activates GSK-3β, and regulates cyclin D1. Resibufogenin can activate central neurons. Resibufogenin has anti-inflammatory activity. Resibufogenin has anti-tumor effects on a variety of tumors such as multiple myeloma, renal cancer, colorectal cancer, pancreatic cancer, and glioma[1][2][3][4][5][6][7][8][9]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bufogenin; Recibufogenin. CAS No. 465-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-N0815.
Resigratinib
Resigratinib (KIN-3248) is an irreversible and orally active covalent inhibitor of FGFR1-4 that effectively inhibits wild-type and drug-resistant mutations (such as FGFR2 V565F, FGFR3 V555M). Resigratinib covalently binds to the Cys492 site of FGFR, blocks the FGFR signaling pathway, inhibits tumor cell proliferation and induces apoptosis. Resigratinib can be used for the study of FGFR2/3-driven solid tumors (such as cholangiocarcinoma and bladder cancer)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KIN-3248. CAS No. 2750709-91-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156632.
Resin acids and Rosin acids, esters with triethylene glycol
Resin acids and Rosin acids, esters with triethylene glycol. CAS No. 8050-25-7.
Resin epoxy, average Mw ~700,000 by GPC. CAS No. 24969-06-0. Molecular formula: C3H5ClO. Mole weight: 92.52g/mol. IUPAC Name: (Z)-3-chloroprop-1-en-1-ol. SMILES: C(C=CO)Cl. InChI: InChI=1S/C3H5ClO/c4-2-1-3-5/h1,3,5H,2H2/b3-1-.
Resiniferatoxin
Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Resiniferatoxin. CAS No. 57444-62-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2333.
Resiniferonol 9,13,14-Orthophenylacetate
Resiniferonol 9,13,14-Orthophenylacetate, a 20-Deacylated derivative of resiniferatoxin and tinyatoxin, is a transient receptor potential vanilloid-1 (TRPV1) agonist. Alternative Names: 6,7-Deepoxy-6,7-didehydro-5-deoxy-21-dephenyl-21-(phenylmethyl)daphnetoxin; [2S-(2α,3aβ,3bβ,6aβ,9aα,9bα,10α,11aβ)]-3a,3b,6,6a,9a,10,11,11a-Octahydro-6a-hydroxy-5-(hydroxymethyl)-8,10-dimethyl-11a-(1-methylethenyl)-2-(phenylmethyl)-7H-2,9b-Epoxyazuleno[5,4-e]-1,3-benzodioxol-7-one; Resiniferonol 9,13,14-ortho-phenylacetate; 57852-42-3; CTK8G2927. CAS No. 57852-42-3. Molecular formula: C28H32O6. Mole weight: 464.55.
RESINOL
RESINOL.
Resinone
Resinone is a bioactive chemical. Alternative Names: Lup-20(29)-en-3-one, 16-hydroxy-, (16β)-; 16-Hydroxylup-20(29)-en-3-one; Lup-20(29)-en-3-one, 16-hydroxy-, (16beta)-; (1R,3aS,4S,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-4-hydroxy-3a,5a,5b,8,8,11a-hexamethyl-1-(prop-1-en-2-yl)icosahydro-9H-cyclopenta[a]chrysen-9-one; 16β-Hydroxylup-20(29)-en-3-one. Grades: >98%. CAS No. 43043-12-5. Molecular formula: C30H48O2. Mole weight: 440.70.
Resins, alkyd
Resins, alkyd. Alternative Names: ALKYD RESIN; Glycerophthalic resins; Including alkyd molding compounds; Phthalic alkyd resins; TERLON; Resins, alkyd. CAS No. 63148-69-6.
Resiquimod is an imidazoquinolinamine and TLR7 agonist with antitumor and antiviral activity. Uses: Resiquimod may be used in immunological and cancer-related cell signaling studies. Alternative Names: R-848; R 848; R848; S 28463; S-28463; S28463; 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-; 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline; Resimiquimod. Grades: ≥95%. CAS No. 144875-48-9. Molecular formula: C17H22N4O2. Mole weight: 314.38.
Resiquimod
Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Uses: Scientific research. Category: Induced disease models products. Alternative Names: R848; S28463. CAS No. 144875-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13740.
Resiquimod-d5
Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R848-d5; S28463-d5. CAS No. 2252319-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-13740S.
Resiquimod-[d5]
Resiquimod-[d5] is an isotope labelled Resiquimod, an imidazoquinolinamine and Toll-like receptor (TLR) agonist. Alternative Names: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol-d5; 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline-d5; 4-Amino-2-ethoxymethyl-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5; R 848-d5; S 28463-d5. Grades: 98%; 98% atom D. CAS No. 2252319-44-9. Molecular formula: C17H17D5N4O2. Mole weight: 319.41.
Resiquimod (GMP)
Resiquimod (R848) (GMP) is Resiquimod (HY-13740) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist. Resiquimod (GMP) can induce human mMDSC to mature into inflammatory macrophages[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R848 (GMP); S28463 (GMP). CAS No. 144875-48-9. Pack Sizes: 10 mg; 50 mg. Product ID: HY-13740G.
Resiquimod (R-848)
Resiquimod (R-848, S28463) is an immune response modifier that acts as a potent TLR 7/TLR 8 agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Resiquimod reduces hepatitis C virus (HCV) infection. Phase 2. Group: Inhibitors. Alternative Names: S28463. CAS No. 144875-48-9. Pack Sizes: 20mg. Product ID: S8133. Formula: C17H22N4O2. Smiles: CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Resistant to Gastric Acid Inactivated Probiotics for Freckle Reduction and Skin Brighten
Inactivated probiotics have good immune functions on human body, because they are rich inlipoteichoic acid, peptidoglycan, exopolysaccharides and fatty acid. For example, EPS of bifidobacterium longum BL21 can reduce the melanin formation of B16 cells significantly. EPS (3.3 mg/ml) inhibit melanin formation rate reducing to 50%.Inactivated probiotics can't be affected by gastric acid, bile and heat. It can be used infood processing as ingredients. The products have strong induced tumor necrosisfactor, interleukin, immunoglobulin and interferon. It can promote theintestinal epithelial tissue to stimulate the intestinal bifidobacteriumproliferation, inhibiting the growth of Clostridium in the large intestine,meanwhile playing a good role of prebiotics. Inactivated probiotics as a functional ingredient can be added infood, health food and medicine. Group: Others. Synonyms: Resistant to Gastric Acid Inactivated Probiotics for Freckle Reduction and Skin Brighten. Purity: 61%~90%. Resistant to Gastric Acid Inactivated Probiotics for Freckle Reduction and Skin Brighten. Cat No: PRBT-028.
Resistoflavine
A rare, boat-shaped, pentacyclic polyketide isolated from several species of streptomyces; exhibits weak antibacterial activity against gram-positive and gram-negative bacteria; exhibits potent cytotoxic activity against tumour cell lines in vitro; inhibits growth, and nucleic acid and protein synthesis in bacillus subtilis. Alternative Names: Resistoflavin; BRN 2491848; (-)-3,5,7,11b-Tetrahydroxy-1,1,9-trimethyl-2H-benzo(cd)pyrene-2,6,10(1H,11bH)-trione. Grades: >98% by HPLC. CAS No. 29706-96-5. Molecular formula: C22H16O7. Mole weight: 392.36.
Resistomycin
Resistomycin. Alternative Names: Croceomycin. CAS No. 20004-62-0. Purity: 95%. Product ID: ACM20004620. Molecular formula: C22H16O6. Mole weight: 376.36. Canonical SMILES: CC1=CC(=C2C3=C4C(=CC(=C13)O)C(C(=O)C5=C(C=C(C(=C45)C2=O)O)O)(C)C)O. Alfa Chemistry - ISO 9001:32057 Certified.
Reslizumab
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sch 55700; CDP-835; JES1-39D10. CAS No. 241473-69-8. Pack Sizes: 1 mg; 2 mg. Product ID: HY-P9949.
Resmetirom
Resmetirom (MGL-3196) is a highly selective and orally active thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM. Resmetirom can be used for the study of noncirrhotic nonalcoholic steatohepatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MGL-3196; VIA-3196. CAS No. 920509-32-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-12216.
Resmetirom
Resmetirom is a novel, first-in-class, selective Thyroid Hormone Receptor-beta (THR-β) partial agonist and the first FDA-approved drug for the treatment of non-cirrhotic Metabolic Dysfunction-Associated Steatohepatitis (MASH), also referred to as NASH. As a significant advancement in the treatment of this complex chronic liver disease, Resmetirom addresses a critical unmet need by targeting the underlying pathology of MASH. Applications: Resmetirom is indicated for the treatment of adult patients with non-cirrhotic mash who have evidence of moderate to advanced liver fibrosis (f2 to f3 stage). its use can lead to a reduction of steatosis, or the pathological accumulation of fat in the liver, as well as associated metabolic abnormalities, such as high levels of serum cholesterol and triglycerides, in order to stop disease progression. Category: Cardiovascular and geriatric medicine apis. Synonyms: 2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile; MGL-3196; VIA-3196. CAS No. 920509-32-6. Product ID: API920509326. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.2. InChIKey: FDBYIYFVSAHJLY-UHFFFAOYSA-N.
Resmetirom Impurity 1
Resmetirom Impurity 1. Uses: For analytical and research use. Molecular formula: C20H18Cl2N6O4. Mole weight: 477.3. Catalog: APB12175.
Resmetirom Impurity 2
Resmetirom Impurity 2. Uses: For analytical and research use. Molecular formula: C17H12Cl2N6O4. Mole weight: 435.22. Catalog: APB12176.
Resmetirom Impurity 3
Resmetirom Impurity 3. Uses: For analytical and research use. CAS No. 1581304-50-8. Molecular formula: C20H15Cl2N3O3. Mole weight: 416.26. Catalog: APB1581304508.
Resminostat
Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1, HDAC3 and HDAC6, with mean IC50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC50 of 877 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAS2410; 4SC-201. CAS No. 864814-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14718.