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Regadenoson, as a coronary vasodilator it is a selective A2A adenosine receptor agonist in myocardial imaging. Uses: A selective a2a adenosine receptor agonist in myocardial imaging. Alternative Names: 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-methylpyrazole-4-carboxamide CVT 3146 CVT-3146 CVT3146 Lexiscan regadenoson. Grades: >99%. CAS No. 313348-27-5. Molecular formula: C15H18N8O5. Mole weight: 390.35.
Regadenoson
Regadenoson. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 313348-27-5. Molecular formula: C15H18N8O5. Mole weight: 390.35. Catalog: APB313348275.
Regadenoson
Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CVT-3146. CAS No. 313348-27-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0168.
Regadenoson-d3
A selective A2A adenosine receptor agonist in myocardial imaging. Group: Biochemicals. Alternative Names: 2-[4-[ (Methylamino)carbonyl]-1H-pyrazol-1-yl]adenosine-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Regadenoson Impurity 1
Regadenoson Impurity 1. Uses: For analytical and research use. Alternative Names: methyl 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. CAS No. 1423073-21-5. Molecular formula: C15H17N7O6. Mole weight: 391.34. Catalog: APB1423073215.
Regadenoson Impurity 11
Regadenoson Impurity 11. Uses: For analytical and research use. Alternative Names: 1-(2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-N-methyl-1H-pyrazole-4-carboxamide. Molecular formula: C15H18N8O5. Mole weight: 390.35. Catalog: APB02206.
Regadenoson Impurity 12
Regadenoson Impurity 12. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-(1H-pyrazol-1-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 1627202-38-3. Molecular formula: C13H15N7O4. Mole weight: 333.3. Catalog: APB1627202383.
Regadenoson Impurity 13
Regadenoson Impurity 13. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-amino-2-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate. CAS No. 79999-39-6. Molecular formula: C16H18ClN5O7. Mole weight: 427.8. Catalog: APB79999396.
Regadenoson Impurity 14
Regadenoson Impurity 14. Uses: For analytical and research use. Alternative Names: (E)-1,1,1-trichloro-4-ethoxybut-3-en-2-one. CAS No. 83124-74-7. Molecular formula: C6H7Cl3O2. Mole weight: 217.48. Catalog: APB83124747.
Regadenoson Impurity 15
Regadenoson Impurity 15. Uses: For analytical and research use. Alternative Names: ethyl 3,3-diethoxypropanoate. CAS No. 10601-80-6. Molecular formula: C9H18O4. Mole weight: 190.24. Catalog: APB10601806.
Regadenoson Impurity 17
Regadenoson Impurity 17. Uses: For analytical and research use. Alternative Names: 6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one. CAS No. 1818-71-9. Molecular formula: C10H13N5O5. Mole weight: 283.24. Catalog: APB1818719.
Regadenoson Impurity 18
Regadenoson Impurity 18. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(2,6-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 2096-10-8. Molecular formula: C10H14N6O4. Mole weight: 282.26. Catalog: APB2096108.
Regadenoson Impurity 19
Regadenoson Impurity 19. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-hydrazinyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 15763-11-8. Molecular formula: C10H15N7O4. Mole weight: 297.27. Catalog: APB15763118.
Regadenoson Impurity 2
Regadenoson Impurity 2. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N,N-dimethyl-1H-pyrazole-4-carboxamide. CAS No. 313348-31-1. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB313348311.
Regadenoson Impurity 20
Regadenoson Impurity 20. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-N-ethyl-1H-pyrazole-4-carboxamide. CAS No. 313348-33-3. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB313348333.
Regadenoson Impurity 21
Regadenoson Impurity 21. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 1702334-23-3. Molecular formula: C10H10N8O. Mole weight: 258.24. Catalog: APB1702334233.
Regadenoson Impurity 22
Regadenoson Impurity 22. Uses: For analytical and research use. Alternative Names: 1-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-(methylamino)-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide. CAS No. 765299-55-6. Molecular formula: C16H20N8O5. Mole weight: 404.38. Catalog: APB765299556.
Regadenoson Impurity 26
Regadenoson Impurity 26. Uses: For analytical and research use. Alternative Names: methyl 1-(6-amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. Molecular formula: C10H9N7O2. Mole weight: 259.22. Catalog: APB02205.
Regadenoson Impurity 27
Regadenoson Impurity 27. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5R)-2-(6-acetamido-2-chloro-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate. Molecular formula: C18H20ClN5O8. Mole weight: 469.83. Catalog: APB01768.
Regadenoson Impurity 3
Regadenoson Impurity 3. Uses: For analytical and research use. Alternative Names: 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylic acid. CAS No. 313348-29-7. Molecular formula: C14H15N7O6. Mole weight: 377.31. Catalog: APB313348297.
Regadenoson Impurity 5
Regadenoson Impurity 5. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 146-77-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB146770.
Regadenoson Impurity 6
Regadenoson Impurity 6. Uses: For analytical and research use. Alternative Names: ethyl 1-(6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)-1H-pyrazole-4-carboxylate. CAS No. 313348-16-2. Molecular formula: C16H19N7O6. Mole weight: 405.37. Catalog: APB313348162.
Regadenoson Impurity 7
Regadenoson Impurity 7. Uses: For analytical and research use. Alternative Names: ethyl 1H-pyrazole-4-carboxylate. CAS No. 37622-90-5. Molecular formula: C6H8N2O2. Mole weight: 140.14. Catalog: APB37622905.
Regadenoson Impurity 8
Regadenoson Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,4S,5R)-2-(6-amino-2-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB01769.
Regadenoson Impurity 9
Regadenoson Impurity 9. Uses: For analytical and research use. Alternative Names: ethyl 2-formyl-3-oxopropanoate. CAS No. 80370-42-9. Molecular formula: C6H8O4. Mole weight: 144.13. Catalog: APB80370429.
Regaloside I
Regaloside I is a natural compound which can be used in content analysis, pharmacological experiments, activity screening, etc. Grades: 98%. CAS No. 126239-78-9. Molecular formula: C20H26O11. Mole weight: 442.42.
Regardsone impurity 1
Regardsone impurity 1. Uses: For analytical and research use. CAS No. 2015222-31-6. Molecular formula: C15H18N8O5. Mole weight: 390.36. Catalog: APB2015222316.
Regardsone impurity 10
Regardsone impurity 10. Uses: For analytical and research use. CAS No. 2015222-35-0. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. Catalog: APB2015222350.
Regardsone impurity 11
Regardsone impurity 11. Uses: For analytical and research use. CAS No. 765299-56-7. Molecular formula: C17H22N8O5. Mole weight: 418.41. Catalog: APB765299567.
Regardsone impurity 12
Regardsone impurity 12. Uses: For analytical and research use. Molecular formula: C18H24N8O5. Mole weight: 432.44. Catalog: APB11350.
Regardsone impurity 15
Regardsone impurity 15. Uses: For analytical and research use. CAS No. 24723-77-1. Molecular formula: C11H15N5O5. Mole weight: 297.27. Catalog: APB24723771.
Regardsone impurity 20
Regardsone impurity 20. Uses: For analytical and research use. CAS No. 650-51-1. Molecular formula: C2Cl3NaO2. Mole weight: 185.36. Catalog: APB650511.
Regardsone impurity 25
Regardsone impurity 25. Uses: For analytical and research use. CAS No. 2156-56-1. Molecular formula: C2HCl2NaO2. Mole weight: 150.92. Catalog: APB2156561.
Regardsone impurity 26
Regardsone impurity 26. Uses: For analytical and research use. CAS No. 1154383-52-4. Molecular formula: C5H7N3O. Mole weight: 125.13. Catalog: APB1154383524.
Regorafenib
Regorafenib (BAY 73-4506) is an orally active, multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ, exhibiting both antitumor and anti-angiogenic activity. Category: Active pharmaceutical ingredients. CAS No. 755037-03-7. Product ID: API755037037. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.82.
Regorafenib
Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine / threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. Grades: >98%. CAS No. 755037-03-7. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83.
Regorafenib
Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-2-pyridinecarboxamide; 4-[4-[N- (4-Chloro-3-trifluoromethylphenyl) ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga. Grades: Highly Purified. CAS No. 755037-03-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 482.82. US Biological Life Sciences.
Worldwide
Regorafenib
Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331.
Regorafenib (BAY 73-4506)
Regorafenib is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit (c-Kit), RET (c-RET) and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively. Regorafenib induces autophagy. Group: Inhibitors. Alternative Names: Fluoro-Sorafenib, BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 5mg. Product ID: S1178. Formula: C21H15ClF4N4O3. Smiles: CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Regorafenib-d3
Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase. Category: Active pharmaceutical ingredients. CAS No. 1255386-16-3. Product ID: API1255386163. Molecular formula: C21H15ClF4N4O3. Mole weight: 485.83.
Regorafenib EP Impurity A
Regorafenib EP Impurity A. Uses: For analytical and research use. CAS No. 757251-39-1. Molecular formula: C13H12FN3O2. Mole weight: 261.26. Catalog: APB757251391.
Regorafenib EP Impurity B
Regorafenib EP Impurity B. Uses: For analytical and research use. CAS No. 2141961-84-2. Molecular formula: C15H14FN3O3. Mole weight: 303.29. Catalog: APB2141961842.
Regorafenib EP Impurity D
Regorafenib EP Impurity D. Uses: For analytical and research use. CAS No. 2438857-80-6. Molecular formula: C27H22F2N6O5. Mole weight: 548.51. Catalog: APB2438857806.
Regorafenib Hydrochloride
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Category: Active pharmaceutical ingredients. Synonyms: BAY73-4506 hydrochloride. CAS No. 835621-07-3. Product ID: API835621073. Molecular formula: C21H16Cl2F4N4O3. Mole weight: 519.28.
Regorafenib Hydrochloride
Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 73-4506 hydrochloride. CAS No. 835621-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13308.
Regorafenib Hydrochloride
Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1. Alternative Names: BAY73-4506 hydrochloride. Grades: >98%. CAS No. 835621-07-3. Molecular formula: C21H16Cl2F4N4O3. Mole weight: 519.28.
Regorafenib Impurity 10
Regorafenib Impurity 10. Uses: For analytical and research use. CAS No. 2098799-12-1. Molecular formula: C19H17FN4O3. Mole weight: 368.37. Catalog: APB2098799121.
Regorafenib Impurity 13
Regorafenib Impurity 13. Uses: For analytical and research use. CAS No. 2909-32-2. Molecular formula: C14H14N2O. Mole weight: 226.28. Catalog: APB2909322.
Regorafenib Impurity 14
Regorafenib Impurity 14. Uses: For analytical and research use. CAS No. 835621-12-0. Molecular formula: C20H13ClF4N4O4. Mole weight: 484.79. Catalog: APB835621120.
Regorafenib Impurity 15
Regorafenib Impurity 15. Uses: For analytical and research use. CAS No. 1343498-72-5. Molecular formula: C20H13ClF4N4O3. Mole weight: 468.79. Catalog: APB1343498725.
Regorafenib Impurity 16
Regorafenib Impurity 16. Uses: For analytical and research use. CAS No. 1343498-71-4. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82. Catalog: APB1343498714.
Regorafenib Impurity 17
Regorafenib Impurity 17. Uses: For analytical and research use. CAS No. 2545933-24-0. Molecular formula: C25H22FN5O4. Mole weight: 475.48. Catalog: APB2545933240.
Regorafenib Impurity 17
Regorafenib Impurity 17. Uses: For analytical and research use. Alternative Names: 4-chloro-3-(trifluoromethyl)aniline. Molecular formula: C7H5ClF3N. Mole weight: 195.57. Catalog: APB01772.
Regorafenib Impurity 18 (Sorafenib Impurity 8)
Regorafenib Impurity 18 (Sorafenib Impurity 8). Uses: For analytical and research use. CAS No. 1379324-09-0. Molecular formula: C7H6Cl2N2O. Mole weight: 205.04. Catalog: APB1379324090.
Regorafenib Impurity 2
Regorafenib Impurity 2. Uses: For analytical and research use. Molecular formula: C16H16FN3O3. Mole weight: 317.32. Catalog: APB09412.
Regorafenib Impurity 20
Regorafenib Impurity 20. Uses: For analytical and research use. CAS No. 370-50-3. Molecular formula: C15H8Cl2F6N2O. Mole weight: 417.13. Catalog: APB370503.
Regorafenib Impurity 21
Regorafenib Impurity 21. Uses: For analytical and research use. CAS No. 9448-54-5. Molecular formula: C9H7ClF3NO2. Mole weight: 253.61. Catalog: APB9448545.
Regorafenib Impurity 27
Regorafenib Impurity 27. Uses: For analytical and research use. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68. Catalog: APB1333390569.
Regorafenib Impurity 29
Regorafenib Impurity 29. Uses: For analytical and research use. CAS No. 352277-93-1. Molecular formula: C12H13ClF3NO2. Mole weight: 295.69. Catalog: APB352277931.
Regorafenib Impurity 30 (Sorafenib Impurity 12)
Regorafenib Impurity 30 (Sorafenib Impurity 12). Uses: For analytical and research use. CAS No. 1153328-25-6. Molecular formula: C13H13N3O2. Mole weight: 243.26. Catalog: APB1153328256.
Regorafenib Impurity 50
Regorafenib Impurity 50. Uses: For analytical and research use. CAS No. 6636-55-1. Molecular formula: C7H6ClNO2. Mole weight: 171.58. Catalog: APB6636551.
Regorafenib Impurity 52
Regorafenib Impurity 52. Uses: For analytical and research use. Molecular formula: C20H19N5O4. Mole weight: 393.4. Catalog: APB09414.
Regorafenib Impurity 53
Regorafenib Impurity 53. Uses: For analytical and research use. Molecular formula: C13H12FN3O2. Mole weight: 261.26. Catalog: APB09413.