A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
RS-22B is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Alternative Names: RS-22 B. Molecular formula: C55H93N3O17. Mole weight: 1068.3.
RS-22C
RS-22C is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Alternative Names: RS-22 C. Molecular formula: C56H95N3O17. Mole weight: 1082.4.
RS-246204 is a R-spondin-1 substitute compound that is able initiate small intestinal organoids without the use of the R-spondin-1 protein. Uses: Scientific research. Category: Signaling pathways. CAS No. 878451-87-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112484.
RS 25344 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 152815-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RS-25344 hydrochloride
RS-25344 hydrochloride is a selective cAMP-phosphodiesterase 4 (PDE 4; PDE IV) inhibitor with an IC50 of 0.28 nM in human lymphocytes. RS-25344 hydrochloride has only weak inhibitory effects on PDE I, II, III (IC50 of >100 μM, 160 μM, 330 μM, respectively). RS-25344 hydrochloride has anti-inflammatory, memory- and cognition enhancing, and antineoplastic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152815-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108621.
RS47
RS47 is a selective RelB inhibitor with a Kd value of 1.1 μM. RS47 also acts as an inhibitor of HCV replication. RS47 can block the non-canonical NF-κB signaling pathway without affecting the canonical pathway. RS47 exerts anti-tumor effects of inhibiting proliferation and promoting apoptosis on colorectal cancer, B-cell lymphoma and other related tumors both in vitro and in vivo by disrupting the binding of RelB to target DNA. RS47 can be used for the research of tumors and infectious diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301655-16-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171579.
RS 504393
RS 504393. Group: Biochemicals. Grades: Purified. CAS No. 300816-15-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RS 504393
RS 504393 is a highly selective CCR2 antagonist. Alternative Names: RS504393; RS 504393; RS-504393; 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one. CAS No. 300816-15-3. Molecular formula: C25H27N3O3. Mole weight: 417.5.
RS 504393
RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). Uses: Scientific research. Category: Signaling pathways. CAS No. 300816-15-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15418.
RS5517
RS5517 is a specific PDZ1-domain antagonist of NHERF1 that prevented its ectopic nuclear entry. RS5517 can be used for the research of colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2227017-46-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-150269.
R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is a methyl donor and cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). While present in all cells, S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is concentrated in cells liver where 85% of all methylation reactions occur. Applications: A methyl donor and cofactor for enzyme-catalyzed methylations. Group: Coenzymes. Synonyms: SAM p-toluenesulfonate salt. CAS No. 17176-17-9. Purity: ≥97%. Mole weight: 570.645. Appearance: Powder. Form: Solid. SAM p-toluenesulfonate salt; R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt; 17176-17-9. Cat No: COEC-088.
Rs-AFP1
Rs-AFP1 is an antibacterial peptide isolated from Brassicaceae species. It has activity against fungi. Alternative Names: Defensin-like protein 1; Sa-AFP1; Gln-Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C242H372N74O70S8. Mole weight: 5694.55.
Rs-AFP2
Rs-AFP2 is an antibacterial peptide isolated from Brassicaceae species. It has activity against fungi. Alternative Names: Raphanus sativus Antifungal Protein 2; Gln-Lys-Leu-Cys-Gln-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Arg-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C244H379N77O68S8. Mole weight: 5735.65.
Rs-AFP4
Rs-AFP4 is an antibacterial peptide isolated from Raphanus sativus (Radish). It has activity against fungi. Alternative Names: Raphanus sativus Antifungal Protein 4; Gln-Lys-Leu-Cys-Glu-Arg-Ser-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Gly-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Ile-Phe-Pro-Tyr-His-Arg-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C243H367N75O72S8. Mole weight: 5747.53.
Rsa I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GT↑AC CA↓TG. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Rhodopseudomonas sphaeroides. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1166RE.
R,S-Ambrisentan-acyl-b-D-glucuronide
R,S-Ambrisentan-acyl-b-D-glucuronide is a pharmaceutical compound utilized in the research of pulmonary arterial hypertension (PAH). It acts as a metabolite of Ambrisentan that is a selective endothelin receptor antagonist. CAS No. 1106685-82-8. Molecular formula: C28H30N2O10. Mole weight: 554.55.
RsaN I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. G↑TAC CAT↓G. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Rhodopseudomonas sphaeroides N. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1167RE.
RSC-1255
RSC-1255 is a potent and selective Vacuolar H?-ATPase (V-ATPase) inhibitor that directly binds the mammalian V-ATPase complex with a Kd = 23 nM. RSC-1255 exhibits preferential cytotoxicity toward KRAS-mutant cancer cells, especially KRASG13D and KRASG12V cells. RSC-1255 induces apoptosis and blocks lysosomal acidification, autophagy, and macropinocytosis in cancer cells. RSC-1255 can be used for the study of KRAS-driven lung and colon cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2171015-78-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-176954.
RSC133
RSC133 is a dual inhibitor of DNA methyltransferase 1 and histone deacetylase 1 inhibitor. RSC133 promotes cell proliferation, up-regulates H3K9 histone acetylation, down-regulates p53, p21, p16/INK4A, and ablates pro-senescence phenotypes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1418131-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-12310.
R,S-Cetirizine dihydrochloride
R,S-Cetirizine dihydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 163837-48-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
R,S-Equol
R,S-Equol. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7-Isoflavandiol; (+/-)-Equol. Grades: Highly Purified. CAS No. 94105-90-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H14O3. US Biological Life Sciences.
R,S equol 4'-sulfate sodium salt. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-[4-(sulfooxy)phenyl]-2H-1-benzopyran-7-ol sodium salt. Grades: Highly Purified. CAS No. 1189685-28-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H13NaO6S. US Biological Life Sciences.
Worldwide
R,S-Equol 7-b-D-glucuronide sodium salt
R,S-Equol 7-b-D-glucuronide sodium salt is a sodium salt derivative of R,S-Equol which is a soy isoflavone daidzein metabolite. It finds utility within the biomedical sector, primarily focusing on the research of hormone-dependent ailments including breast and prostate cancer. Alternative Names: 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-yl-b-D-glucuronide. CAS No. 38482-82-5. Molecular formula: C21H21NaO9. Mole weight: 440.38.
RSK4-IN-1
RSK4-IN-1 is a potent RSK4 inhibitor with a IC50 value of 9.5 nM. RSK4-IN-1 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755819-10-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132891.
RSL3
RSL3 ((1S,3R)-RSL3) is a ferroptosis activator in a VDAC-independent manner,exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Group: Inhibitors. CAS No. 1219810-16-8. Pack Sizes: 5mg. Product ID: S8155. Formula: C23H21ClN2O5. Smiles: COC(=O)C1CC2=C(C(N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24. Storage Conditions: 2 years -80 in solvent.
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (1S,3R)-RSL3. CAS No. 1219810-16-8. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-100218A.
RSM-932A
RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC50s of 1 and 33 μM for human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A acts as the first in humans compound targeting ChoKα. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TCD-717. CAS No. 850807-63-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101144.
RSPACER CEP
RSPACER CEP is a biomedical product designed to study Chronic Exertional Compartment Syndrome. Alternative Names: 5'-O-Dimethoxytrityl-1'-Deoxyribose-2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; rSpacer TBDMS CE Phosphoramidite; 2'-OTBS abasic amidite; D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2-cyanoethyl bis(1-methylethyl)phosphoramidite. Grades: >95%. CAS No. 159299-31-7. Molecular formula: C41H59N2O7PSi. Mole weight: 750.99.
Rsr2 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CG↑GWCCG GCCWG↓GC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Rhodobacter sphaeroides 12. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1168RE.
R-Styrene oxide
R-Styrene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 20780-53-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
RSVA 405. Group: Biochemicals. Grades: Purified. CAS No. 140405-36-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RTA
A ready-to-apply print on non-skid frictionizer that will indicate via UV light with a viscosity specifically designed for Flexo Printing and Rod Coaters. Uses: Pulp & paper. Group: Anti skid. Manufacturing grinding and machining fluids for brittle composites. Categories: Paper anti-skid coating, Flexo print frictionizer.
RTA-408
RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Alternative Names: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. Grades: >98%. CAS No. 1474034-05-3. Molecular formula: C33H44F2N2O3. Mole weight: 554.723.
RTA-II
Ready-to-apply print on non-skid frictionizer with a viscosity specifically designed for Flexo Printing and Rod Coaters. This Anti-Skid produces high consistent slide angles. Benefits include no dusting, no separation after freezing. RTA-II will not clog ani-lox rollers or leave residue on equipment. Uses: Pulp & paper. Group: Anti skid. Manufacturing grinding and machining fluids for brittle composites. Categories: Paper anti-skid coating, Flexo print frictionizer.
RT-AM
RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 2280796-94-1. Pack Sizes: 1 mg. Product ID: HY-108715A.
RTD-1
RTD-1 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria, Antiviral and fungi. Alternative Names: Cyclic-(GVCRCICTRGFCRCLCRR); Rhesus theta-defensin 1; Gly-Phe-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Ile-Cys-Thr-Arg. CAS No. 251442-64-5. Molecular formula: C82H137N33O19S6. Mole weight: 2081.6.
RTD-2
RTD-2 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria, Antiviral and fungi. Alternative Names: Cyclic-(GVCRCLCRRGVCRCICRR); Rhesus theta-defensin 2; Gly-Val-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Leu-Cys-Arg-Arg. Molecular formula: C80H142N36O18S6. Mole weight: 2088.6.
RTD-4
RTD-4 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Gly-Ile-Cys-Arg-Cys-Ile-Cys-Thr-Arg-Gly-Phe-Cys-Arg-Cys-Ile-Cys-Val-Leu. Molecular formula: C82H143N27O20S6. Mole weight: 2019.57.
RTD-5
RTD-5 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Gly-Ile-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Ile-Cys-Val-Leu. Molecular formula: C80H148N30O19S6. Mole weight: 2026.6.
R-Thalidomide
The R-enantiomer of Thalidomide which interacts directly with the protein cereblon (CRBN; IC50=8.5 nM), a ubiquitously-expressed E3 ligase. Alternative Names: (R)-Thalidomide; (+)-Thalidomide; (R)-(+)-thalidomide; D-Thalidomide; 2614-06-4; R-(+)-Thalidomide; Thalidomide, (R)-; QN61H68KLK; 2-[(3R)-2,6-dioxopiperidin-3-yl]isoindole-1,3-dione; CHEBI:61917; Phthalimide, N-(2,6-dioxo-3-piperidyl)-, D-(+)-; (R)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-, (R)-; 2-[(3R)-2,6-dioxopiperidin-3-yl]-2,3-dihydro-1H-isoindole-1,3-dione; 2-[(3R)-2,6-dioxopiperidin-3-yl]-1H-isoindole-1,3(2H)-dione; 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione; NSC 91729; NSC-91729; (R)-(D)-Thalidomide. Grades: > 95%. CAS No. 2614-6-4. Molecular formula: C13H10N2O4. Mole weight: 258.24.
R-Thioctic acid Tromethamine
used in preparation of Piperazine Dithioctate for treatment of diabetic multiple neuritis, obesity. Category: Active pharmaceutical ingredients. CAS No. 137314-40-0. Product ID: API137314400. Molecular formula: C12H25NO5S2. Mole weight: 327.461.
RTI-112
RTI-112 is a synthetic stimulant and cocaine analog belonging to the phenyltropane group. RTI-112 acts as a non-selective serotonin-norepinephrine-dopamine reuptake inhibitor (SNRDI) with similar selectivty to cocaine. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Chloro-3-methylphenyl)-8-methyl-8-Azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-112. Grades: Highly Purified. CAS No. 150653-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-113
RTI-113 is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride; RTI 113; RTI 4229-113. Grades: Highly Purified. CAS No. 141807-57-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
RTI-177
RTI-177 is a phenyltropane cocaine analog that acts as a dopamine-selective uptake inhibitors. RTI-177 has a lower abuse liability than cocaine but with similar potency. RTI-177 does not bind to anticocaine catalytic antibodies that are used as potential medication for cocaine abusers and thus can be used simultaneously in treatments. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3. 2. 1]octane Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3. 2. 1]octane Hydrochloride; RTI 177; RTI 4229-177. Grades: Highly Purified. CAS No. 170939-95-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-336
RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3. 2. 1]octane Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3. 2. 1]octane Hydrochloride; RTI 336; RTI 4229-336. Grades: Highly Purified. CAS No. 204069-50-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
RTI-51 Hydrochloride
RTI-51 is a semi-synthetic alkaloid that is part of the phenyltropane group with psychosimulant activity. RTI-51 does not bind to anticocaine catalytic antibodies that are used as potential medication for cocaine abusers and thus can be used simultaneously in treatments. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Bromophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Bromophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-51 Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-7470-44
RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinsons disease (PD)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 825658-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147319.
RTM solution A
RTM solution A.
RTM solution B
RTM solution B.
RTM solution C
RTM solution C.
R-(+)-Tolterodine
A muscarinic receptor antagonist. Used in the treatment of urinary incontinence. Group: Biochemicals. Alternative Names: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol; (R)-(+)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine; (R)-Tolterodine; Kabi 2234; PNU 200583; Tolterodine. Grades: Highly Purified. CAS No. 124937-51-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
rTRD01
rTRD01 is an orally active, specific TDP-43 binder that targets the RRM1 and RRM2 domains of TDP-43. rTRD01 partially disrupts the interaction between TDP-43 and c9orf72 repeat RNA, but does not affect the binding of TDP-43 to canonical binding sequences. rTRD01 exhibits significant neuroprotective effects in zebrafish models, improves motor function and protects against paraquat (a widely used herbicide)-induced neurodegeneration, with no teratogenicity at high concentrations. rTRD01 is not a general antioxidant and cannot counteract Rotenone (HY-B1756)-induced neuronal death. rTRD01 can be used to study amyotrophic lateral sclerosis and other TDP-43 proteinopathies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1332175-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153898.
RTx-152
RTx-152 traps Polθ on DNA and is an allosteric Polθ-pol inhibitor (IC50: 6.2 nM). RTx-152 selectively kills HR-deficient cancer cells, and suppresses PARP inhibitor resistance in multiple genetic backgrounds, including homologous recombination (HR)-proficient cells. RTx-152 selectively kills BRCA2-null cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3035072-48-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161431.
RTx-161
RTx-161 is a DNA polymerase θ inhibitor with an IC50 of 4.1 nM. RTx-161 induces DNA damage, PARP cleavage, apoptosis, and selectively kills homologous recombination-deficient (HRD) cells. RTx-161 acts synergistically with PARP inhibitors to suppress PARP inhibitor resistance in cancer cells. RTx-161 can be used for the research of BRCAG12C mutant cancer and HR-deficient cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3035072-49-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-161430.
RU 24969
RU 24969 is a preferential 5-HT1B agonist, with a Ki of 0.38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 66611-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16688.
RU 24969 hemisuccinate
RU 24969 hemisuccinate. Group: Biochemicals. Grades: Purified. CAS No. 66611-27-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RU 26752
RU 26752. Group: Biochemicals. Grades: Purified. CAS No. 76676-33-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RU 28318, potassium salt
RU 28318, potassium salt. Group: Biochemicals. Grades: Purified. CAS No. 76676-34-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RU-301
RU-301 is a pan TAM inhibitor that blocks Gas6-induced TAM activation and tumorigenicity. RU-301 significantly reduces nonalcoholic steatohepatitis (NASH) fibrosis, along with attenuates ERK activation and TGFβ1 expression. RU-301 can be used in studies of cancer and nonalcoholic steatohepatitis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1110873-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119039.
RU.521
RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RU320521. CAS No. 2262452-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-114180.
RU.521 (RU320521)
RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS / dsDNA complex with Kd of 36.2 nM. Group: Inhibitors. Alternative Names: RU320521. CAS No. 2262452-06-0. Pack Sizes: 5mg. Product ID: S6841. Formula: C19H12Cl2N4O3. Smiles: CC1=C(C(=O)N(N1)C2=NC3=C(N2)C=CC(=C3Cl)Cl)C4C5=CC=CC=C5C(=O)O4. Storage Conditions: 3 years -20°C powder.
United States; Europe
RU 58668
RU 58668. Group: Biochemicals. Grades: Purified. CAS No. 151555-47-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RU 58841
RU 58841 is a new non-steroidal antiandrogen which has potential for use in treating androgen-dependent skin disorders such as acne, hirsutism and androgen-dependent alopecia. Alternative Names: RU-58841; RU58841; RU 58841; 4-(4,4-dimethyl-2,5-dioxo-3-(4-hydroxybutyl)-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile. CAS No. 154992-24-2. Molecular formula: C17H18F3N3O3. Mole weight: 369.34.
RU-59063
RU-59063 is a nonsteroidal androgen or selective androgen receptor modulator (SARM). Alternative Names: RU 59063; 4-(3-(4-Hydroxybutyl)-4,4-dimethyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile. CAS No. 155180-53-3. Molecular formula: C17H18F3N3O2S. Mole weight: 385.4.
Rubanthrone A
Rubanthrone A belongs to a kind of anthrones and is extracted from the aerial parts of Rubus ulmifolius Schott. It has moderate cytotoxicity against MCF-7 cell line. Grades: 98.0%. CAS No. 441764-20-1. Molecular formula: C17H14O10. Mole weight: 378.29.