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| Product | Description | |
|---|---|---|
| Rosuvastatin Impurity 93 | Rosuvastatin Impurity 93. Uses: For analytical and research use. Alternative Names: sodium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-methoxyhept-6-enoate. Molecular formula: C23H29FN3NaO6S. Mole weight: 517.55. Catalog: APB01688. |  |
| Rosuvastatin Impurity 94 | Rosuvastatin Impurity 94. Uses: For analytical and research use. Alternative Names: tert-butyl 2-((4S,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 1642330-94-6. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB1642330946. | |
| Rosuvastatin Impurity 95 | Rosuvastatin Impurity 95. Uses: For analytical and research use. Alternative Names: tert-butyl 2-((4S,6R)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 2375865-91-9. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB2375865919. | |
| Rosuvastatin Impurity 96 | Rosuvastatin Impurity 96. Uses: For analytical and research use. Alternative Names: sodium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dimethoxyhept-6-enoate. Molecular formula: C24H31FN3NaO6S. Mole weight: 531.57. Catalog: APB01687. | |
| Rosuvastatin Impurity 97 | Rosuvastatin Impurity 97. Uses: For analytical and research use. Alternative Names: tert-butyl 2-((4R,6R)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB01686. | |
| Rosuvastatin Impurity 98 | Rosuvastatin Impurity 98. Uses: For analytical and research use. Alternative Names: N-(4-(4-fluorophenyl)-6-isopropyl-5-methylpyrimidin-2-yl)-N-methylmethanesulfonamide. Molecular formula: C16H20FN3O2S. Mole weight: 337.41. Catalog: APB01685. | |
| Rosuvastatin Impurity 99 | Rosuvastatin Impurity 99. Uses: For analytical and research use. Alternative Names: N-(5-(bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-2-hydroxy-N,2-dimethylpropane-1-sulfonamide. Molecular formula: C19H25BrFN3O3S. Mole weight: 474.39. Catalog: APB01684. | |
| Rosuvastatin Impurity Z-5 | Rosuvastatin Impurity Z-5. Uses: For analytical and research use. CAS No. 160009-36-9. Molecular formula: C16H18FN3O2. Mole weight: 303.34. Catalog: APB160009369. | |
| Rosuvastatin Intermediate Impurity 2 | Rosuvastatin Intermediate Impurity 2. Uses: For analytical and research use. Alternative Names: methyl 4-(4-fluorophenyl)-2-hydroxy-6-isopropylpyrimidine-5-carboxylate. CAS No. 488798-37-4. Molecular formula: C15H15FN2O3. Mole weight: 290.29. Catalog: APB488798374. | |
| Rosuvastatin isomer-23/Rosuvastatin calcium salt isomer photodegradation-6 | Rosuvastatin isomer-23/Rosuvastatin calcium salt isomer photodegradation-6. Uses: For analytical and research use. Alternative Names: 854898-53-6 (free acid); (3R,5S)-5-((S)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoic acid calcium. CAS No. 854898-50-3. Molecular formula: C22H27FN3O6S·1/2Ca. Mole weight: 500.57. Catalog: APB854898503. | |
| Rosuvastatin lactone | Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 503610-43-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138166. |  |
| Rosuvastatin Lactone | A selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Rosuvastatin Lactone-d6 | A selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Rosuvastatin Lactone dehydration Impurity | Rosuvastatin Lactone dehydration Impurity. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-(4-fluorophenyl)-6-isopropyl-5-(2-(6-oxo-3,6-dihydro-2H-pyran-2-yl)vinyl)pyrimidin-2-yl)-N-methylmethanesulfonamide. CAS No. 1246665-85-9. Molecular formula: C22H24FN3O4S. Mole weight: 445.51. Catalog: APB1246665859. | |
| Rosuvastatin Methyl Ester | An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Alternative Names: (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester. Grades: > 95%. CAS No. 147118-40-9. Molecular formula: C23H30FN3O6S. Mole weight: 495.57. |  |
| Rosuvastatin Methyl Intermediate Impurity | Rosuvastatin Methyl Intermediate Impurity. Uses: For analytical and research use. Alternative Names: methyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 851440-19-2. Molecular formula: C26H34FN3O6S. Mole weight: 535.63. Catalog: APB851440192. | |
| Rosuvastatin Photodegradation of calcium salt isomers-8 | Rosuvastatin Photodegradation of calcium salt isomers-8. Uses: For analytical and research use. Alternative Names: (3R,5S)-5-(8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)benzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoic acid. Molecular formula: C22H26FN3O6S. Mole weight: 479.52. Catalog: APB01676. | |
| Rosuvastatin Related Compound 17 | Rosuvastatin Related Compound 17. Uses: For analytical and research use. Alternative Names: tert-butyl 2-((4S,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular formula: C13H22O5. Mole weight: 258.15. Catalog: APB01697. | |
| Rosuvastatin Related Compound 20 | Rosuvastatin Related Compound 20. Uses: For analytical and research use. Alternative Names: tert-butyl 2-((4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate. Molecular formula: C13H22O5. Mole weight: 258.15. Catalog: APB01695. | |
| Rosuvastatin Sodium | Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium. CAS No. 147098-18-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17504B. | |
| Rosuvastatin Sodium Salt | Water Content: Group: Biochemicals. Grades: Highly Purified. CAS No. 287714-41-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| Rosuvastatin tert-Butyl Ester | Rosuvastatin tert-Butyl Ester. Group: Biochemicals. Alternative Names: (3R, 5S, 6E)-7-[4- (4-Fluorophenyl)-6- (1-methylethyl)-2-[methyl (methylsulfonyl)amino]-5-pyrimidinyl]-3, 5-dihydroxy-6-heptenoic Acid 1,1-Dimethylethyl Ester; (3R, 5S, 6E) -7-[4- (4-Fluorophenyl) -6-isopropyl-2-[ (methanesulfonyl) methylamino]pyrimidin-5-yl]-3, 5-dihydroxyhept-6-enoic Acid tert-Butyl Ester; tert-Butyl (6E) -7-[4- (4-fluorophenyl) -6-isopropyl-2-[methyl (methylsulfonyl) amino]pyrimidin-5-yl]- (3R, 5S) -3, 5-dihydroxyhept-6-enoate; tert-Butyl Rosuvastatin. Grades: Highly Purified. CAS No. 355806-00-7. Pack Sizes: 100mg. Molecular Formula: C26H36FN3O6S, Molecular Weight: 537.64. US Biological Life Sciences. | Worldwide |
| Rosuvastatin triphenylphosphonium bromide | Rosuvastatin triphenylphosphonium bromide. Group: Biochemicals. Alternative Names: [ [4- (4-Fluorophenyl) -6- (1-methylethyl) -2- [methyl (methylsulfonyl) amino] -5-pyrimidinyl] methyl] triphenylphosphonium bromide; Rosuvastatin intermediate Z-8.2. Grades: Highly Purified. CAS No. 885477-83-8. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C34H34BrFN3O2PS. US Biological Life Sciences. | Worldwide |
| Rosuvastatin Z-Isomer Calcium Salt | Rosuvastatin Z-Isomer Calcium Salt is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Alternative Names: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6Z)-; Calcium (3R,5S,Z)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; (3R,5S,6Z)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt. Grades: ≥95%. CAS No. 1444772-08-0. Molecular formula: C22H27FN3O6S.1/2Ca. Mole weight: 500.57. | |
| Rosyrane Super | Rosyrane Super. CAS No. 60335-71-9. VIGON Item # 503372. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, floral pyran. |  America & Internationally |
| Rosyrane Super | Rosyrane Super. CAS No. 60335-71-9. Molecular formula: C12H14O. Mole weight: 174.24. | |
| Rotenone | Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Category: Induced disease models products. CAS No. 83-79-4. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B1756. | |
| Rotenone | Rotenone is a botanical insecticide that occurs naturally in seeds and stems of several plants. Rotenone is a mitochondrial electron transport inhibitor, inhibiting NADH/DB oxidoreductase and NADH oxidase with IC50 values of 28.8 and 5.1 nM, respectively. Alternative Names: Rotenone; NSC 26258; NSC-26258; NSC26258; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: ≥95% by HPLC. CAS No. 83-79-4. Molecular formula: C23H22O6. Mole weight: 394.42. | |
| Rotenone | Rotenone. Group: Biochemicals. Alternative Names: (-)-Rotenone; (-)-cis-Rotenone; 5' β-Rotenone; CFT Legumine; Cube-Pulver; Dactinol; Deril; Derrin; Derris; Derris (insecticide); Dri-kil; Liquid Derris; NSC 26258; NSC 8505; Nicouline; Noxfish; Paraderil; Ronone; Rotena; Rotenon; Rotenox; Rotocide; Tubatoxin; 1,2,12,12aα-Tetrahydro-2α-isopropenyl-8,9-dimethoxy-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aαH)-one; (2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one. Grades: Highly Purified. CAS No. 83-79-4. Pack Sizes: 2.5g. Molecular Formula: C23H22O6, Molecular Weight: 394.42. US Biological Life Sciences. | Worldwide |
| Rotenone | 1g Pack Size. Group: Analytical Reagents, Biochemicals. Formula: C23H22O6. CAS No. 83-79-4. Prepack ID 26479483-1g. Molecular Weight 394.42. See USA prepack pricing. |  |
| Rotenone (Standard) | Rotenone (Standard) is the analytical standard of Rotenone. This product is intended for research and analytical applications. Rotenone is a mitochondrial electron transport chain complex I inhibitor. Rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. Uses: Scientific research. Category: Signaling pathways. CAS No. 83-79-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B1756R. | |
| Rotigaptide | Rotigaptide is a peptide drug used to treat arrhythmia. Alternative Names: CHEMBL450656; GAP-486; ZP-123; ZP 123; ZP123 peptide; ZP-123 (ZEALAND); acetyl-tyrosyl-prolyl-hydroxyprolyl-glycyl-alanyl-glycinamide. Grades: >98%. CAS No. 355151-12-1. Molecular formula: C28H39N7O9. Mole weight: 617.65. | |
| Rotigaptide | Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZP123. CAS No. 355151-12-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-106225. | |
| Rotigotine | Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-0923; (-)-N 0437. CAS No. 99755-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-75502. | |
| Rotigotine-[d7] | Rotigotine-[d7] is a labelled compound of Rotigotine. Rotigotine is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of Parkinson's disease (PD) and Willis-Ekbom Disease. Alternative Names: (S)-6-[propyl-D7(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol. Grades: >98%. CAS No. 2070009-56-0. Molecular formula: C19H18D7NOS. Mole weight: 322.52. | |
| Rotigotine-[d7] Hydrochloride | Rotigotine-[d7] Hydrochloride is the labelled hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50 values of 13 nM and 0.71 nM for D2 and D3 receptor respectively. Grades: > 95%. CAS No. 2070009-57-1. Molecular formula: C19H18NOSD7·HCl. Mole weight: 358.98. | |
| Rotigotine EP Impurity A | Rotigotine EP Impurity A. Uses: For analytical and research use. CAS No. 112835-48-0. Molecular formula: C19H25NOS. Mole weight: 315.48. Catalog: APB112835480. | |
| Rotigotine EP Impurity B | Rotigotine EP Impurity B. Uses: For analytical and research use. CAS No. 101470-23-9. Molecular formula: C13H19NO. Mole weight: 205.3. Catalog: APB101470239. | |
| Rotigotine EP Impurity B HCl | Rotigotine EP Impurity B HCl. Uses: For analytical and research use. CAS No. 1231158-77-2. Molecular formula: C13H20ClNO. Mole weight: 241.76. Catalog: APB1231158772. | |
| Rotigotine EP Impurity C | Rotigotine EP Impurity C. Uses: For analytical and research use. CAS No. 153409-14-4. Molecular formula: C16H19NOS. Mole weight: 273.39. Catalog: APB153409144. | |
| Rotigotine EP Impurity D | Rotigotine EP Impurity D. Uses: For analytical and research use. CAS No. 1369625-04-6. Molecular formula: C18H23NOS. Mole weight: 301.45. Catalog: APB1369625046. | |
| Rotigotine EP Impurity E | Rotigotine EP Impurity E. Uses: For analytical and research use. Molecular formula: C19H25NO2S. Mole weight: 331.47. Catalog: APB10848. | |
| Rotigotine EP Impurity F | Rotigotine EP Impurity F. Uses: For analytical and research use. CAS No. 835654-68-7. Molecular formula: C21H27NO2S. Mole weight: 357.51. Catalog: APB835654687. | |
| Rotigotine EP Impurity G | Rotigotine EP Impurity G. Uses: For analytical and research use. CAS No. 1422357-33-2. Molecular formula: C22H25NOS2. Mole weight: 383.57. Catalog: APB1422357332. | |
| Rotigotine EP Impurity H | Rotigotine EP Impurity H. Uses: For analytical and research use. CAS No. 1148154-91-9. Molecular formula: C20H27NOS. Mole weight: 329.5. Catalog: APB1148154919. | |
| Rotigotine EP Impurity I | Rotigotine EP Impurity I. Uses: For analytical and research use. Molecular formula: C26H31NO3S2. Mole weight: 469.66. Catalog: APB10850. | |
| Rotigotine EP Impurity J | Rotigotine EP Impurity J. Uses: For analytical and research use. Molecular formula: C25H31NOS2. Mole weight: 425.65. Catalog: APB10849. | |
| Rotigotine EP Impurity K | Rotigotine EP Impurity K. Uses: For analytical and research use. CAS No. 51927-48-1. Molecular formula: C10H10O. Mole weight: 146.19. Catalog: APB51927481. | |
| Rotigotine HCl | The hydrochloride salt form of rac-Rotigotine, a mixture of S- and R-Rotigotine, is an effective and highly selective D-2 receptor agonist which could be used in the treatment of the Parkinson's disease. Ki: 0.69 nM. Uses: The hydrochloride salt form of rac-rotigotine is an effective and highly selective d-2 receptor agonist which could be used in the treatment of the parkinson's disease. Alternative Names: 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride. Grades: 95%. CAS No. 102120-99-0. Molecular formula: C19H26ClNOS. Mole weight: 351.93. | |
| Rotigotine Hydrochloride | The hydrochloride salt form of Rotigotine which is a dopamine D2 and D3 receptor agonist and has been shown to be effective in the treatment of Parkinson's disease. IC50: 13 nM and 0.71 nM for D2 and D3 receptor respectively. Uses: The hydrochloride salt form of rotigotine which is a dopamine d2 and d3 receptor agonist and has been shown to be effective in the treatment of parkinson's disease. Alternative Names: Rotigotine hydrochloride; Rotigotine HCl; Rotigotine (Hydrochloride); (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; (6S)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride. Grades: >99 %. CAS No. 125572-93-2. Molecular formula: C19H26ClNOS. Mole weight: 351.93. | |
| Rotigotine Hydrochloride | It is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinsons disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 125572-93-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Rotigotine Hydrochloride | Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-0923 Hydrochloride. CAS No. 125572-93-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-A0007. | |
| Rotigotine Hydrochloride ((6S)-5,6,7,8-Tetrahydro-6-[propyl[2--(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride, Dopamine Receptor Agonist, Rotigotine Hydrochloride, Neupro) | A highly potent non-ergoline dopamine D2 and D3 receptor agonist (Ki = 13 and 0.71nM for D2 and D3 respectively). Also displays significant affinity for 5-HT1A and adrenergic alpha2B receptors. Transdermally used in treatment of Parkinson's disease and restless legs syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 125572-93-2. Pack Sizes: 10mg. Molecular Formula: C??H??NOS HCl. US Biological Life Sciences. | Worldwide |
| Rottlerin | Rottlerin, a principal phenolic compound of the Kamala plant Mallotus philippinensis, originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Recently, it has been shown to inhibit a wide range of protein kinases, and most potently to inhibit PRAK and MAPKAP-K2 (IC50 values are 1.9 and 5 μM respectively). Uses: Enzyme inhibitors. Alternative Names: 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone. Grades: ≥98% (HPLC). CAS No. 82-08-6. Molecular formula: C30H28O8. Mole weight: 516.55. | |
| Rottlerin | Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation[1][2][3]. Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection[4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mallotoxin; NSC 56346; NSC 94525. CAS No. 82-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18980. | |
| Rotundatin | Rotundatin is a 9,10-dihydrophenanthrene derivative isolated from the orchid, Dendrobium rotundatum. Alternative Names: 2,5,9-Trihydroxy-4-methoxy-9,10-dihydrophenanthrene. Grades: >98%. CAS No. 144506-16-1. Molecular formula: C15H14O4. Mole weight: 258.27. | |
| Rotundatin | Rotundatin. Group: Biochemicals. CAS No. 144506-16-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Rotundic acid | Rotundic acid is a triterpenoid found in the leaves of Ilex pubescens Hook. It exhibits potent tumor cell growth inhibiting properties. Alternative Names: (3beta,4alpha)-3,19,23-Trihydroxyurs-12-en-28-oic acid; Ilexolic acid A. Grades: >98%. CAS No. 20137-37-5. Molecular formula: C30H48O5. Mole weight: 488.70. | |
| Rotundic acid | Rotundic acid. Alternative Names: 3β,19α,23-Trihydroxyurs-12-ene-28-oic acid. CAS No. 20137-37-5. Purity: >98.0%. Product ID: FFC-AR-20137375. Molecular formula: C30H48O5. Mole weight: 488.7. IUPAC Name: (1R,2R,4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-1,10-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Rotundic Acid | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 20137-37-5. Pack Sizes: 10mg, 20mg. US Biological Life Sciences. | Worldwide |
| Rotundine | An analgesic drug found in Chinese herbal medicine, used to treat heart disease and liver damage. Group: Biochemicals. Alternative Names: (13aS)-5, 8, 13, 13a-Tetrahydro-2, 3, 9, 10-tetramethoxy-6H-dibenzo[a, g]quinolizine; O,O-Dimethyl-N-demethyl-cyclanoline; Gindarine; (-)-2,3,9,10-Tetramethoxyberbine; (-)-Corydalis B; (-)-S-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; Hyndarine; N-Demethyl-O,O'-dimethylcyclanoline; N-Demethyl-O,O'-dimethylsteponine; THP. Grades: Highly Purified. CAS No. 483-14-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Roussin red methyl ester | Roussin red methyl ester. CAS No. 16071-96-8. Product ID: ACM16071968. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Rovalpituzumab | Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of ADC Rovalpituzumab Tesirine, which has been investigated for the treatment of SCLC. CAS No. 1613313-01-1. | |
| Rovalpituzumab | Rovalpituzumab is a humanized monoclonal antibody against delta-like protein 3 (DLL3). Rovalpituzumab can be used in the synthesis of antibody-drug conjugate (ADC), Rovalpituzumab Tesirine. Rovalpituzumab has activity against small cell lung cancer (SCLC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SC-0001. CAS No. 1613313-01-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99043. | |
| Rovalpituzumab tesirine | Rovalpituzumab tesirine (SC-002) is an antibody-drug conjugate (ADC) with anticancer effects. Rovalpituzumab tesirine contains a DLL3-targeting antibody Rovalpituzumab (HY-P99043) tethered to a cytotoxic agent pyrrolobenzodiazepine by means of a protease-cleavable linker. Rovalpituzumab tesirine can be used for the stduy of small cell lung cancer (SCLC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SC-002. CAS No. 1613313-09-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132257. | |
| Rovelizumab | Rovelizumab is a humanized monoclonal leukointegrin antibody. Rovelizumab is a monoclonal antibody directed against the CD11/CD18 cell adhesion proteins. Rovelizumab can be used for research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI) and stroke[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hu23F2G. CAS No. 339086-79-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99891. | |
| Rovunaptabin | Rovunaptabin (ARC 183) is an aptamer, a single-stranded DNA molecule composed of 15 deoxynucleotides. It acts as a broad-spectrum neutralizer of pathogenic G-protein-coupled receptor autoantibodies. Rovunaptabin can be used in research related to cardiomyopathy and pulmonary hypertension[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARC 183; BC 007. CAS No. 145563-68-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148826. | |
| Roxadustat | Roxadustat. Category: Active pharmaceutical ingredients. Synonyms: 2-(4-hydroxy-1-Methyl-7-phenoxyisoquinoline-3-carboxaMido)acetic acid;2-(4-HYDROXY-1-METHYL-7-PHENOXYISOQUINOLINE-3-CARBOXAMIDO)ACETIC ACID;[[(4-Hydroxy-1-Methyl-7-phenoxyisoquinolin-3-yl)carbonyl]aMino]acetic Acid;N-[(4-Hydroxy-1-Methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine;FG-4592/FG4592;Glycine, N-[(4-hydroxy-1-Methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-;FG-4592(ASP1517). CAS No. 808118-40-3. Product ID: API808118403. Molecular formula: C19H16N2O5. Mole weight: 352.34. EINECS: 813-400-2. Appearance: solid. Standard: DMF in preparation. |  |
| Roxadustat | Roxadustat is an orally active hypoxia-inducible factor prolyl-hydroxylase (PHD) inhibitor (HIF-PHI) that promotes erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FG-4592. CAS No. 808118-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13426. | |
| Roxadustat acyl-β-D-glucuronide | Roxadustat acyl-β-D-glucuronide is a metabolite of roxadustat, which is an orally active hypoxia-inducible factor (HIF) prolyl-hydroxylase (PHD) inhibitor. Roxadustat itself is used to treat anemia in patients with chronic kidney disease by promoting erythropoiesis through increasing endogenous erythropoietin, improving iron regulation, and reducing hepcidin. Alternative Names: N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycinyl β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolylcarbonylamino)acetoxy]tetrahydro-2H-pyran-2-carboxylic acid. Grades: ≥95%. Molecular formula: C25H24N2O11. Mole weight: 528.46. | |
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