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| Product | Description | |
|---|---|---|
| RO5256390 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| RO-5256390 | RO-5256390 is a novel selective full agonist of the trace amine-associated receptor 1 (TAAR1). It blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties. It promotes vigilance in rats and shows pro-cognitive and antidepressant-like properties in rodent and primate models. It may improve not only the positive symptoms but also the negative symptoms and cognitive deficits, without causing adverse effects such as motor impairments or weight gain. It may be used as treatment of cocaine addiction. Uses: Ro-5256390 has antipsychotic-like properties. it may be used as treatment of cocaine addiction. Synonyms: RO5256390; RO 5256390; RO-5256390; (S)-4-((S)-2-phenylbutyl)-4,5-dihydrooxazol-2-amine;(4S)-4-[(2S)-2-phenylbutyl]-4,5-dihydro-1,3-oxazol-2-amine. Grades: >98 %. CAS No. 1043495-96-0. Molecular formula: C13H18N2O. Mole weight: 218.30. |  |
| RO5263397 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO 5263397 | RO5263397 is a selective trace amine-associated receptor 1(TAAR1) agonist. TAAR1 is a drug discovery target for cocaine addiction. RO5263397 is efficacious in reducing cocaine-mediated behaviors and it can dose-dependently prevent cocaine-induced lowering of ICSS thresholds. Uses: Cocaine addiction. Synonyms: RO 5263397; RO5263397; RO-5263397; (4S)?-4-(3-Fluoro-2-methylphenyl)?-4,?5-dihydro-2-oxazolamine. Grades: 98%. CAS No. 1357266-05-7. Molecular formula: C10H11FN2O. Mole weight: 194.21. | |
| Ro 5-3335 | Ro 5-3335. Group: Biochemicals. Grades: Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Ro 5-3335 | Ro 5-3335, a benzodiazepine, is a core binding factor (CBF) leukemia inhibitor. It is highly active in vitro (IC50 = 0.1-1.0 microM [corrected]) against HIV-1 viruses of AIDS resistant or non-resistant to zidovudine (AZT). Synonyms: Ro 5-3335; Ro-5-3335; Ro 5 3335; 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-pyrrol-2-yl- (7CI,8CI); NSC 66020; NSC66020; NSC-66020. Grades: ≥98% by HPLC. CAS No. 30195-30-3. Molecular formula: C13H10ClN3O. Mole weight: 259.69. | |
| Ro5-3335 | Ro5-3335 Inhibitor. Uses: Scientific use. Product Category: T4687. CAS No. 30195-30-3. |  |
| Ro5-3335 | Ro5-3335, a benzodiazepine, acts as an inhibitor of core binding factor (CBF) leukemia. Ro5-3335 is a RUNX1-CBF? interaction inhibitor that represses RUNX1/CBFB-dependent transactivation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30195-30-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108470. |  |
| RO5454948 | Mirk-IN-1 (Dyrk1B/A-IN-1) is a highly efficient and selective inhibitor of Dyrk1B and Dyrk1A, with IC50 values of 68 and 22nM respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mirk-IN-1; Dyrk1B/A-IN-1. CAS No. 1386979-55-0. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12838. | |
| RO5 Drug-like Natural Product Library | 2743 is a collection of natural products that meet the "Lipinski's Rule of Five" and have high potential for drug discovery. - Most of the NPs have clear biological activities, with various functions including anti-tumor, anti-inflammatory, antioxidant, neuroprotection and more. - Structural diversity, containing flavonoids, saponins, terpenoids, alkaloids and other categories. - Various detection techniques such as NMR, HPLC/LCMS to ensure accurate structure and high purity of the products and reduce false positives. Uses: Scientific use. Product Category: L6160. Categories: RO5 Drug-like Natural Product Libraries. | |
| Ro60-0175 | Ro60-0175 is a potent and selective agonist of 5-HT 2C receptor. Ro60-0175 reduces self-administration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-08-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123838. | |
| Ro 60-0175 fumarate | Ro 60-0175 fumarate is a potent and selective SR-2 agonist. It is a potent, selective 5-HT2 receptor agonist, with selectivity for the 5-HT2C subtype (pKi= 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Synonyms: Ro 60-0175 fumarate; Ro-60-0175 fumarate; Ro 60 0175 fumarate; Ro600175 fumarate; (αS)-6-Chloro-5-fluoro-α-methyl-1H-indole-1-ethanamine fumarate. Grades: ≥98% by HPLC. CAS No. 169675-09-6. Molecular formula: C11H12ClFN2.C4H4O4. Mole weight: 342.75. | |
| Ro 60-0175 fumarate | Ro 60-0175 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 169675-09-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro60-0175 fumarate | Ro60-0175 fumarate is a potent and selective agonist of 5-HT 2C receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-103140. | |
| Ro 61-8048 | Potent and competitive kynurenine 3-hydroxylase inhibitor (IC50 = 37 nM). Shows antidystonic, anticonvulsant and neuroprotective effects in vivo. Blood-brain barrier permeable. Orally active. Synonyms: Ro61-8048; Ro 61-8048; Ro-61-8048; Ro618048; Ro 618048; Ro-618048. Grades: >98%. CAS No. 199666-03-0. Molecular formula: C17H15N3O6S2. Mole weight: 421.45. | |
| Ro 61-8048 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 61-8048 | Ro 61-8048 is an orally active and selective inhibitor of kynurenine 3-hydroxylase, with an IC50 of 37 nM. Ro 61-8048 provokes a significant increase of extracellular kynurenic acid concentrations[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199666-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12347. | |
| Ro 61-8048 | Ro 61-8048. Group: Biochemicals. Grades: Purified. CAS No. 199666-03-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 64-5229 | Ro 64-5229. Group: Biochemicals. Grades: Purified. CAS No. 246852-46-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 64-5229 | Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. Synonyms: Ro64-5229; Ro64-5229; Ro64-5229; (Z)-1-[2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole; (Z)-1-[2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole; (Z)-1-[2-Cycloheptyloxy-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole (9CI); 1-[(1Z)-2-(Cycloheptyloxy)-2-(2,6-dichlorophenyl)ethenyl]-1H-1,2,4-triazole. Grades: ≥99% by HPLC. CAS No. 246852-46-0. Molecular formula: C17H19Cl2N3O. Mole weight: 352.26. | |
| Ro 64-6198 | Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC 50 value of 25.6 nM. Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors. Ro 64-6198 can be used for stress and anxiety, addiction, neuropathic pain, cough, and anorexia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280783-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-12844. | |
| Ro 65-6570 Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 67-4853 | Ro 67-4853 is a positive allosteric modulator of metabotropic glutamate 1 receptors (mGluR1) (pEC50 value is 7.16 for the rat mGlu1a receptor). It also enhance glutamate-induced calcium signaling through both the human and mouse mGlu1a receptors. Synonyms: (9H-Xanthen-9-ylcarbonyl)-carbamic acid butyl ester; Ro67-4853; Ro 67-4853; Ro-67-4853. Grades: ≥99% by HPLC. CAS No. 302841-89-0. Molecular formula: C19H19NO4. Mole weight: 325.36. | |
| Ro 67-4853 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 67-4853 | Ro 67-4853. Group: Biochemicals. Grades: Purified. CAS No. 302841-89-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 67-7476 | Ro 67-7476 is a positive allosteric metabotropic mGlu1 receptor modulator without activity at human mGlu1 receptors. Synonyms: Ro67-7476; Ro-67-7476; Ro 67-7476. (2S)-2-(4-Fluorophenyl)-1-[(4-methylphenyl)sulfonyl]-pyrrolidine. Grades: ≥99% by HPLC. CAS No. 298690-60-5. Molecular formula: C17H18FNO2S. Mole weight: 319.39. | |
| Ro 67-7476 | Ro 67-7476. Group: Biochemicals. Grades: Purified. CAS No. 298690-60-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 67-7476 | Ro 67-7476 is a potent positive allosteric modulator of mGluR 1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC 50 of 60.1 nM [1] [2]. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate ( EC 50 =163.3 nM) [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 298690-60-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100403. | |
| RO6806051 | RO6806051 (compound12) is a potent dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with good selectivity and absorption, distribution, metabolism and excretion (eADME) properties[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433901-75-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161702. | |
| Ro 6842262 | Ro 6842262 is a potent LPA1 antagonist (IC50 = 25 nM) with >1,200-fold selectivity for LPA1 over LPA3. Synonyms: RO-6842262;RO 6842262; RO6842262; 1-[4'-[4-Methyl-5-[[[(1R)-1-phenylethoxy]carbonylamino]-1H-1,2,3-triazol-1-yl][1,1'-biphenyl]-4-yl]cyclopropanecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 1396006-71-5. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
| RO6889678 | RO6889678 is an inhibitor of HBV with a complex ADME profile. RO6889678 showed an intracellular enrichment of 78-fold in hepatocytes, with an apparent intrinsic clearance of 5.2 μl/min per mg protein and uptake and biliary clearances of 2.6 and 1.6 μl/min per mg protein, respectively. The induction potential of RO6889678 on cytochrome P450 (P450) enzymes and transporters at steady state was assessed and cotreatment with ritonavir revealed a complex drug-drug interaction with concurrent P450 inhibition and moderate UDP-glucuronosyltransferase induction. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RO6889678; RO-6889678; RO 6889678. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1578153-27-1. Molecular formula: C21H20ClFN4O5S. Mole weight: 494.92. Purity: >98%. IUPACName: (S)-4-(((R)-6-(2-Chloro-4-fluorophenyl)-5-(methoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-3-carboxylic acid. Canonical SMILES: O=C([C@H]1N(CC2=C(C(OC)=O)[C@H](C3=CC=C(F)C=C3Cl)N=C(C4=NC=CS4)N2)CCOC1)O. Product ID: ACM1578153271. Alfa Chemistry ISO 9001:2015 Certified. |  |
| RO8191 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO8191 | RO8191 is an agonist of interferon α receptor type 2 (IFNAR2) effective against HCV with EC50 value of 200 nM. RO8191 phosphorylates STAT1 and STAT2, which functions as a gateway to the type I IFN signal cascade, and stimulates the phosphorylation of STAT3, 5 and 6. Synonyms: Ro 494-8191; 2-[2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole; 8-(1,3,4-oxadiazol-2-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a][1,8]naphthyridine. Grades: ≥98%. CAS No. 691868-88-9. Molecular formula: C14H5F6N5O. Mole weight: 373.2. | |
| Ro 8-4304 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 8-4304 hydrochloride | Ro 8-4304 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1312991-77-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 8-4304 hydrochloride | Ro 8-4304 hydrochloride is a non-competitive NMDA receptor antagonist with > 100 fold selectivity for NR2B-containing receptors over NR2A-containing receptors. Synonyms: 4-[3-[4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1(2H)-pyridinyl]-2-hydroxypropoxy]benzamide hydrochloride; Ro 8-4304; Ro84304; Ro-8-4304; Ro 8-4304 hydrochloride; Ro 8-4304 HCl. Grades: ≥99% by HPLC. CAS No. 1312991-77-7. Molecular formula: C21H23FN2O3.HCl. Mole weight: 406.88. | |
| RO8994 | RO8994, a spiroindolinone derivative, is an effective MDM2 inhibitor and has been found to have prabable activity against haematological malignancies. IC50: 5 nM and 20 nM in HTRF binding assays and MTT proliferation assays respectively. Uses: Ro8994 is an effective mdm2 inhibitor and has been found to have prabable activity against haematological malignancies. Synonyms: RO8994; RO-8994; RO 8994. Grades: 98%. CAS No. 1309684-94-3. Molecular formula: C31H31Cl2FN4O4. Mole weight: 613.51. | |
| RO9021 | RO9021 is ATP-competative and selective inhibitor of spleen tyrosine kinase (SYK) with IC50 value of 5.6 nM. RO-9021 is a highly selective SYK inhibitor with low S-scores of 0.003 for S(99) and 0.015 for S(90). This indicates that SYK is the only kinase with 99% competition with RO-9021 (1 uM) in a total of 392 tested kinases. RO9021 also can selectively suppress B-cell receptor signaling. Synonyms: RO-9021; RO 9021; RO9021. 6-[(1R,2S)-2-Amino-cyclohexylamino]-4-(5,6-dimethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide. Grades: 98%. CAS No. 1446790-62-0. Molecular formula: C18H25N7O. Mole weight: 355.45. | |
| Ro 90-7501 | Ro 90-7501. Group: Biochemicals. Grades: Purified. CAS No. 293762-45-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 90-7501 | Ro 90-7501, under the IUPCA name 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine, a type of aminoquinolines, is an inhibitor of Aβ42 fibril assembly so that can reduce Aβ42-induced toxicity (EC50 = 2 μM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: RO 90-7501; RO 90 7501; RO 907501; RO907501; RO-90-7501; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501; 293762-45-5; GNF-Pf-5510; STK367782; CBChromo1_000149; AC1LGN68; Cambridge id 5180073; CBDivE_006377; R0529_SIGMA; CHEMBL578741; SCHEMBL10002475; STOCK2S-20922; CTK8E9490; DTXSID80356431; HMS3262E21; HMS3269A19; Tox21_500670; ZINC18206988; AKOS000635167; AKOS001483260; CCG-221974; LP00670; MCULE-7528949788; NCGC00094031-06; NCGC00261355-01; BAS 03420670; HE063215; HE332505; ST078196; AB00074940-01; AG-690/09405007; BRD-K58299615-001-02-7; 3B1-004024; 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2'-(4-aminophenyl)-1H,1'H-2,5'-bibenzimidazol-5-amine; 2-[2-(4-aminophenyl)benzimidazol-6-yl]benzimidazole-6-ylamine; 2'-(4-Amino-phenyl)-3H,3'H-[2,5']bibenzoimidazolyl-5-ylamine; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501|2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2-[2-(4-aminophenyl)-1H-1,3-benzodiazol-6-yl]-1H-1,3-benzodiazol-6-amine; 2-[2-(4-AMINOPHENYL)-3H-1,3-BENZODIAZOL-5-YL]-3H-1,3-BENZODIAZOL-5-AMINE. CAS No. 293762-45-5. Molecular formula: C20H16N6. Mole weight: 340.39. | |
| RO-9187 | RO-9187 is a potent inhibitor of HCV virus replication in the replicon system. It is excellent substrates for deoxycytidine kinase and were phosphorylated with efficiencies up to 3-fold higher than deoxycytidine. It is a new class of antiviral nucleoside with promising preclinical properties as potential medicines for the treatment of HCV infection. Synonyms: RO-9187; RO 9187; RO9187. Grades: >98%. CAS No. 876708-03-1. Molecular formula: C9H12N6O5. Mole weight: 284.23. | |
| ROAD-1 | Oral Mucosal Alpha-Defensin is an antimicrobial peptide found in Macaca mulatta (Rhesus monkey), and has antibacterial and antifungal activity. Synonyms: Rhesus macaque oral alpha-defensin-1; Oral Mucosal Alpha-Defensin. Grades: >98%. Molecular formula: C145H245N61O44S6. Mole weight: 3739.35. | |
| Road dust (trace elements) | certified Reference Material. Group: Certified reference materials (crms). | |
| Robatumumab | Robatumumab (Sch 717454) is an anti-human IGF-1R ( insulin-like growth factor receptor-1 ) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Sch 717454; 19D12. CAS No. 934235-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99218. | |
| Robatumumab | Robatumumab is a human monoclonal antibody directed against insulin-like growth factor 1 receptor (IGF-1R). Robatumumab has been used in the research of colorectal cancer. Synonyms: Sch 717454; 19D12; MK-7454. CAS No. 934235-44-6. | |
| Robenacoxib | Robenacoxib is a nonsteroidal anti-inflammatory and analgesic agent. Robenacoxib is a selective COX-2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220991-32-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118078. | |
| Robenacoxib. | A novel COX-2 selective inhibitor, as a. Group: Biochemicals. Alternative Names: 5-Ethyl-2-[ (2, 3, 5, 6-tetrafluorophenyl) amino]benzeneacetic Acid. Grades: Highly Purified. CAS No. 220991-32-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Robenidine-d8 hydrochloride | analytical standard. Group: Application areas. | |
| Robenidine hydrochloride | analytical standard. Group: Application areaspharma & vet compounds & metabolitesstandards for environmental regulatory methodspharma & vet compounds & metabolitesapi standards. Alternative Names: Cycostat, Robenidine hydrochloride, Guanidine, 1,3-bis[(p-chlorobenzylidene)amino]-, monohydrochloride (8CI),2,2'-Bis[(4-chlorophenyl)methylene]carbonimidic Dihydrazide Hydrochloride (1:1), Carbonimidic dihydrazide, bis[(4-chlorophenyl)methylene]-, monohydrochloride (9CI), 1,3-Bis[(p-chlorobenzylidene)amino]guanidine monohydrochloride, Robenzidene, NCL 812. | |
| Robenidine hydrochloride | Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC 50 s of 8.1 and 4.7 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 25875-50-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2157. | |
| Robinetin | 3,7,3,4,5-pentahydroxyflavone. CAS No. 490-31-3. Product ID: 2-08170. Molecular formula: C15H10O7. Mole weight: 302.2. Purity: >95%. |  |
| Robinetin | Robinetin. Group: Biochemicals. Alternative Names: 3,3',4',5',7-Pentahydroxyflavone. Grades: Highly Purified. CAS No. 490-31-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H10O7. US Biological Life Sciences. | Worldwide |
| Robinin | Robinin. Group: Biochemicals. CAS No. 301-19-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Robinose | Robinose is an extensively adopted bioactive compound, predominantly employed for studying diabetes mellitus owing to its inherent antihyperglycemic attributes. Synonyms: 6-O-(6-Deoxy-a-L-mannopyranosyl)-b-D-galactopyranose; Rha(a1-6)b-Gal; 6-O-a-rhamnopyranosyl-b-galactopyranoside; Robinobiose. CAS No. 552-74-9. Molecular formula: C12H22O10. Mole weight: 326.30. | |
| Roblitinib | Roblitinib (FGF-401) is an orally active and highly selective FGFR4 inhibitor with an IC 50 of 1.9 nM [1]. Roblitinib has antitumor activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FGF-401. CAS No. 1708971-55-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101568. | |
| Robotnikinin | Robotnikinin is an inhibitor of Shh signaling that functions via repressing Gli-mediated transcription in primary human keratinocytes and synthetic human skin in a concentration-dependent manner. Synonyms: N-[(4-Chlorophenyl)methyl]-2-(5,12-dioxo-2-phenyl-1-oxa-4-azacyclododec-8-en-6-yl)acetamide. Grades: ≥97%. CAS No. 1132653-79-2. Molecular formula: C25H27ClN2O4. Mole weight: 455. | |
| Robotnikinin (N-2-acetamide) | Sonic hedgehog (Shh) signaling small molecule modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein. Group: Biochemicals. Alternative Names: N--2-acetamide. Grades: Highly Purified. CAS No. 1132653-79-2. Pack Sizes: 1mg. Molecular Formula: C25H27ClN2O4. US Biological Life Sciences. | Worldwide |
| Roburic Acid | Roburic Acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 6812-81-3. Pack Sizes: 20mg. Molecular Formula: C30H48O2, Molecular Weight: 440.7. US Biological Life Sciences. | Worldwide |
| Robustaflavone | A dimer impurity of impurity of Ipriflavone. Synonyms: 6-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one. Grades: > 95%. CAS No. 49620-13-5. Molecular formula: C30H18O10. Mole weight: 538.47. | |
| Robustol methyl ether | Cas No. 27825-39-4. Molecular formula: C29H42O4. Mole weight: 454.64. | |
| ROC-325 | ROC-325 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1859141-26-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103706. | |
| ROC-325 | ROC-325 is a lysosomal-mediated autophagy inhibitor. It exhibits superior preclinical anticancer activity compared with hydroxychloroquine (HCQ). Uses: Antineoplastic agents. Synonyms: ROC 325; ROC325; 1-[2-[2-[(7-chloroquinolin-4-yl)amino]ethyl-methylamino]ethylamino]-4-methylthioxanthen-9-one. CAS No. 1859141-26-6. Molecular formula: C28H27ClN4OS. Mole weight: 503.06. | |
| Rocaglamide | Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1R)-2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide. Product Category: Inhibitors. CAS No. 84573-16-0. Molecular formula: C29H31NO7. Mole weight: 505.6. Purity: 95%+. Product ID: ACM84573160. Alfa Chemistry ISO 9001:2015 Certified. | |
| Rocaglamide | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Rocaglamide | Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-?B activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Roc-A. CAS No. 84573-16-0. Pack Sizes: 10 mM * 1 mL; 500 ?g; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19356. | |
| Rocatinlimab | Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 451; KHK4083. CAS No. 2431972-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99955. | |
| Roccellaric acid | Synonyms: 3-Furancarboxylic acid, tetrahydro-4-methyl-5-oxo-2-tridecyl-, [2R-(2α,3β,4α)]-; (2R,3S,4S)-Tetrahydro-4-methyl-5-oxo-2-tridecyl-3-furancarboxylic acid; (+)-Roccellaric acid; Dihydroneoprotolichesteric acid; Nephromopsinic acid (-). CAS No. 19464-85-8. Molecular formula: C19H34O4. Mole weight: 326.47. | |
| Rochelle salt | Rochelle salt is an organic-inorganic compound commonly used as a catalyst and complexing reagent. It can be used to catalyze or promote certain chemical reactions, and is widely used in batteries, pharmaceuticals and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: L-Tartaric acid potassium sodium salt tetrahydrate; Potassium sodium tartrate tetrahydrate; Sodium potassium tartrate tetrahydrate. CAS No. 6381-59-5. Pack Sizes: 25 g; 100 g. Product ID: HY-Y1332. | |
| Rociletinib | Rociletinib is a third-generation irreversible kinase inhibitor of epidermal growth factor receptor (EGFR). Rociletinib was shown to inhibit the proliferation of non-small cell lung cancer (NSCLC) cells expressing mutant EGFR. It also exhibits anti-tumor activity in NSCLC EGFR mutant xenograft models. Synonyms: CO-1686; CO1686; CO 1686; AVL-301; AVL 301; AVL301; CNX-419; CNX 419; CNX419; N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxyanilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide. CAS No. 1374640-70-6. Molecular formula: C27H28F3N7O3. Mole weight: 555.562. | |
| Rociletinib | Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the K i values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CO-1686; AVL-301; CNX-419. CAS No. 1374640-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15729. | |
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