A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
A selective antagonist for CCR2 receptors (IC50 = 0.36 and 17.8uM for CCR2b and CCR1 receptors, respectively). Blocks monocyte chemoattractant protein-1 induced calcium influx and chemotaxis (IC50 = 32nM and 1.7uM respectively). A potential anti-inflammatory therapeutic agent by Inhibiting alpha1A, alpha1D and 5-HT1A receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 300815-41-2. Pack Sizes: 5mg. US Biological Life Sciences.
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RS-127445
RS-127445 is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-87-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15419A.
RS 127445 hydrochloride
RS 127445 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199864-86-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-86-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15419.
RS 127445 Hydrochloride
A selective, high affinity , orally bioavailable 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi = 9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites including the closely related 5-HT2A and 5-HT2C receptors. In isolated human cells, RS-127445 exbhited an IC50 greater than 10uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 199864-86-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RS17
RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPα, on the surface membrane of macrophages. The main regulatory mechanism of RS17 is to prevent CD47 from transmitting selective phagocytosis signals to SIRPα by binding to CD47 , so that macrophages do not recognize tumor cells as their own tissue, but phagocytose them as foreign substances, thereby inhibiting immune escape of tumor cells. RS17 can be used to study the mechanism of anti-tumor response and immune escape [1]. Uses: Scientific research. Group: Peptides. CAS No. 2415545-08-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10420.
RS-22A
RS-22A is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Synonyms: RS-22 A. Molecular formula: C54H91N3O17. Mole weight: 1054.3.
RS-22B
RS-22B is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Synonyms: RS-22 B. Molecular formula: C55H93N3O17. Mole weight: 1068.3.
RS-22C
RS-22C is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Synonyms: RS-22 C. Molecular formula: C56H95N3O17. Mole weight: 1082.4.
RS-246204 is a R-spondin-1 substitute compound that is able initiate small intestinal organoids without the use of the R-spondin-1 protein. Uses: Scientific research. Group: Signaling pathways. CAS No. 878451-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112484.
RS 25344 hydrochloride
RS 25344 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 152815-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
RS 504393 is a selective CCR2 chemokine receptor antagonist ( IC 50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 300816-15-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15418.
RS 504393
RS 504393. Group: Biochemicals. Grades: Purified. CAS No. 300816-15-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is a methyl donor and cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). While present in all cells, S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt is concentrated in cells liver where 85% of all methylation reactions occur. Applications: A methyl donor and cofactor for enzyme-catalyzed methylations. Group: Coenzymes. Synonyms: SAM p-toluenesulfonate salt. CAS No. 17176-17-9. Purity: ≥97%. Mole weight: 570.645. Appearance: Powder. Form: Solid. SAM p-toluenesulfonate salt; R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt; 17176-17-9. Cat No: COEC-088.
RS 67333 hydrochloride
RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pK i of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride has neuroprotective effects, and can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 168986-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101341.
Rs-AFP1 is an antibacterial peptide isolated from Brassicaceae species. It has activity against fungi. Synonyms: Defensin-like protein 1; Sa-AFP1; Gln-Lys-Leu-Cys-Glu-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C242H372N74O70S8. Mole weight: 5694.55.
Rs-AFP2
Rs-AFP2 is an antibacterial peptide isolated from Brassicaceae species. It has activity against fungi. Synonyms: Raphanus sativus Antifungal Protein 2; Gln-Lys-Leu-Cys-Gln-Arg-Pro-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Arg-Leu-Glu-Lys-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Val-Phe-Pro-Ala-His-Lys-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C244H379N77O68S8. Mole weight: 5735.65.
Rs-AFP4
Rs-AFP4 is an antibacterial peptide isolated from Raphanus sativus (Radish). It has activity against fungi. Synonyms: Raphanus sativus Antifungal Protein 4; Gln-Lys-Leu-Cys-Glu-Arg-Ser-Ser-Gly-Thr-Trp-Ser-Gly-Val-Cys-Gly-Asn-Asn-Asn-Ala-Cys-Lys-Asn-Gln-Cys-Ile-Asn-Leu-Glu-Gly-Ala-Arg-His-Gly-Ser-Cys-Asn-Tyr-Ile-Phe-Pro-Tyr-His-Arg-Cys-Ile-Cys-Tyr-Phe-Pro-Cys. Molecular formula: C243H367N75O72S8. Mole weight: 5747.53.
Rsa I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. GT↑AC CA↓TG. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Rhodopseudomonas sphaeroides. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1166RE.
RsaN I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. G↑TAC CAT↓G. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Rhodopseudomonas sphaeroides N. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1167RE.
R,S-Equol. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol; 4',7-Isoflavandiol; (+/-)-Equol. Grades: Highly Purified. CAS No. 94105-90-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C15H14O3. US Biological Life Sciences.
Worldwide
R,S-Equol (4,7-Isoflavandiol)
A human urinary metabolite of Daidzein. Its als a natural estrogenic metabolite from soy isoflavones. Group: Biochemicals. Alternative Names: 4,7-Isoflavandiol. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
A cell-permeable cyanoacrylamide compound that acts as a potent, reversible, and selective inhibitor of ribosomal S6 kinase 2 (RSK2; IC50 = 12 and 2.5nM for wild-type and T493M RSK2, respectively). Shown to act by covalently modifying Cys436 at the ATP-binding site. Exhibits good selectivity over NEK2 and PLK1 (IC50 = 530nM and 2.2uM) and does not affect the activity of a panel of 26 other protein kinases. Also shown to block phosphorylation of mitogen and stress activated kinases (MSK) 1, 2, and 3 in PMA-stimulated COS7 cells (IC50 ~100nM) and CREB phosphorylation in PMA- or UV-stimulated HeLa cells (IC50 ~300nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (1S,3R)-RSL3. CAS No. 1219810-16-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100218A.
RSM-932A
RSM-932A (TCD-717) is a specific ChoK? inhibitor with IC50s of 1 and 33 ?M for human recombinant ChoK? and ChoK? enzymes, respectively. RSM-932A acts as the first in humans compound targeting ChoK?. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCD-717. CAS No. 850807-63-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101144.
R-SPONDIN-1 human
recombinant, expressed in CHO cells, ?95% (SDS-PAGE), ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Rsr2 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CG↑GWCCG GCCWG↓GC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Rhodobacter sphaeroides 12. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA, 50% glycerol. Cat No: ET-1168RE.
R-Styrene oxide
R-Styrene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 20780-53-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
RSVA 405. Group: Biochemicals. Grades: Purified. CAS No. 140405-36-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RSV-IN-1
RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC 50 of 0.11 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 861139-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112673.
RTD-1 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria, Antiviral and fungi. Synonyms: Cyclic-(GVCRCICTRGFCRCLCRR); Rhesus theta-defensin 1; Gly-Phe-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Ile-Cys-Thr-Arg. CAS No. 251442-64-5. Molecular formula: C82H137N33O19S6. Mole weight: 2081.6.
RTD-2
RTD-2 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria, Antiviral and fungi. Synonyms: Cyclic-(GVCRCLCRRGVCRCICRR); Rhesus theta-defensin 2; Gly-Val-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Leu-Cys-Arg-Arg. Molecular formula: C80H142N36O18S6. Mole weight: 2088.6.
RTD-4
RTD-4 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Ile-Cys-Arg-Cys-Ile-Cys-Thr-Arg-Gly-Phe-Cys-Arg-Cys-Ile-Cys-Val-Leu. Molecular formula: C82H143N27O20S6. Mole weight: 2019.57.
RTD-5
RTD-5 is an antibacterial peptide isolated from Macaca mulatta. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Gly-Ile-Cys-Arg-Cys-Leu-Cys-Arg-Arg-Gly-Val-Cys-Arg-Cys-Ile-Cys-Val-Leu. Molecular formula: C80H148N30O19S6. Mole weight: 2026.6.
RTI-112 is a synthetic stimulant and cocaine analog belonging to the phenyltropane group. RTI-112 acts as a non-selective serotonin-norepinephrine-dopamine reuptake inhibitor (SNRDI) with similar selectivty to cocaine. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chloro-3-methylphenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Chloro-3-methylphenyl)-8-methyl-8-Azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-112. Grades: Highly Purified. CAS No. 150653-92-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-113
RTI-113 is a 3-phenyltropane analogue that acts as a potent and selective dopamine uptake inhibitor. RTI-113 has been shown to reduce cocaine self-administration at high occupancy of dopamine transporter. Studies suggest that RTI-113 and its analogs may be useful tools for developing potential agonist therapies for cocaine dependence. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Phenyl Ester Hydrochloride; RTI 113; RTI 4229-113. Grades: Highly Purified. CAS No. 141807-57-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
RTI-177
RTI-177 is a phenyltropane cocaine analog that acts as a dopamine-selective uptake inhibitors. RTI-177 has a lower abuse liability than cocaine but with similar potency. RTI-177 does not bind to anticocaine catalytic antibodies that are used as potential medication for cocaine abusers and thus can be used simultaneously in treatments. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3. 2. 1]octane Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-2-(3-phenyl-5-isoxazolyl)-8-azabicyclo[3. 2. 1]octane Hydrochloride; RTI 177; RTI 4229-177. Grades: Highly Purified. CAS No. 170939-95-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-336
RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3. 2. 1]octane Hydrochloride; [1R-(exo, exo)]-3-(4-Chlorophenyl)-8-methyl-2-[3-(4-methylphenyl)-5-isoxazolyl]-8-azabicyclo[3. 2. 1]octane Hydrochloride; RTI 336; RTI 4229-336. Grades: Highly Purified. CAS No. 204069-50-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
RTI-51 Hydrochloride
RTI-51 is a semi-synthetic alkaloid that is part of the phenyltropane group with psychosimulant activity. RTI-51 does not bind to anticocaine catalytic antibodies that are used as potential medication for cocaine abusers and thus can be used simultaneously in treatments. Group: Biochemicals. Alternative Names: (1R, 2S, 3S, 5S)-3-(4-Bromophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo, exo)]-3-(4-Bromophenyl)-8-methyl-8-azabicyclo[3. 2. 1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-51 Hydrochloride. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RTI-7470-44
RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinsons disease (PD)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 825658-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147319.
R-Tirofiban HCl
R-Tirofiban HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151414-72-1. Molecular formula: C22H37ClN2O5S. Mole weight: 477.06. Catalog: APB151414721.
RTM solution A
RTM solution A. Group: Electronic materials.
RTM solution B
RTM solution B. Group: Electronic materials.
RTM solution C
RTM solution C. Group: Electronic materials.
R-(+)-Tolterodine
A muscarinic receptor antagonist. Used in the treatment of urinary incontinence. Group: Biochemicals. Alternative Names: 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenol; (R)-(+)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine; (R)-Tolterodine; Kabi 2234; PNU 200583; Tolterodine. Grades: Highly Purified. CAS No. 124937-51-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
rTRD01
rTRD01 is a TDP-43 ligand that binds to TDP-43s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102-269). rTRD01 partially disrupts TDP-43s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1332175-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153898.
RU 24969
RU 24969 is a preferential 5-HT1B agonist, with a Ki of 0.38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66611-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16688.