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| Product | Description | |
|---|---|---|
| Rocuronium Bromide Impurity 11 | Rocuronium Bromide Impurity 11. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one. Molecular formula: C19H30O2. Mole weight: 290.44. Catalog: APB01767. |  |
| Rocuronium Bromide Impurity 13 | Rocuronium Bromide Impurity 13. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(4H)-one. CAS No. 14639-79-3. Molecular formula: C19H28O. Mole weight: 272.43. Catalog: APB14639793. | |
| Rocuronium Bromide Impurity 14 | Rocuronium Bromide Impurity 14. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one. CAS No. 14935-81-0. Molecular formula: C19H28O. Mole weight: 272.43. Catalog: APB14935810. | |
| Rocuronium Bromide Impurity 15 | Rocuronium Bromide Impurity 15. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate. CAS No. 50588-22-2. Molecular formula: C21H30O2. Mole weight: 314.46. Catalog: APB50588222. | |
| Rocuronium Bromide Impurity 17 (EP impurity D) | An impurity of Rocuronium.Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 3-Acetyl-17-deacetyl Rocuronium Bromide;1-[(2β,3α,5α,16β,17β)-3-(Acetyloxy)-17-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-63-5. Molecular formula: C32H53N2O4. Br. Mole weight: 609.69. |  |
| Rocuronium Bromide Impurity 26 | Rocuronium Bromide Impurity 26. Uses: For analytical and research use. Alternative Names: (1R,2S,5aS,6aS,7aR,8aS,10aS)-8a,10a-dimethyl-2-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[7,8]phenanthro[2,3-b]oxiren-1-ol. Molecular formula: C23H37NO2. Mole weight: 359.55. Catalog: APB01765. | |
| Rocuronium Bromide Impurity 27 | Rocuronium Bromide Impurity 27. Uses: For analytical and research use. Alternative Names: 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-(allyloxy)-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. Molecular formula: C35H57BrN2O4. Mole weight: 649.74. Catalog: APB01764. | |
| Rocuronium Bromide Impurity 32 | Rocuronium Bromide Impurity 32. Uses: For analytical and research use. Alternative Names: (3R,4R,5R,8R,9S,10R,13S,14S,16S,17R)-10,13-dimethyl-4-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C27H46N2O3. Mole weight: 446.67. Catalog: APB01763. | |
| Rocuronium Bromide Impurity 34 | Rocuronium Bromide Impurity 34. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. CAS No. 144209-33-6. Molecular formula: C27H46N2O2. Mole weight: 430.67. Catalog: APB144209336. | |
| Rocuronium Bromide Impurity 35 | Rocuronium Bromide Impurity 35. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-hydroxy-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate. Molecular formula: C29H48N2O4. Mole weight: 488.70. Catalog: APB02186. | |
| Rocuronium Bromide Impurity 38 | Rocuronium Bromide Impurity 38. Uses: For analytical and research use. Alternative Names: (2R,3R,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C27H46N2O3. Mole weight: 446.67. Catalog: APB02111. | |
| Rocuronium Bromide Isomer Impurity | Rocuronium Bromide Isomer Impurity. Uses: For analytical and research use. Alternative Names: Rocuronium Bromide Impurity 33; 1-((3R,4R,5R,8R,9S,10R,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-4-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. Molecular formula: C32H53N2O4·Br. Mole weight: 609.67. Catalog: APB01762. | |
| Rocuronium EP Impurity A | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-Acetate; (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 17-Acetate; Desallyl Rocuronium. Grades: 95%. CAS No. 119302-24-8. Molecular formula: C29H48N2O4. Mole weight: 488.72. | |
| Rocuronium EP Impurity C | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 17-Desacetyl Rocuronium Bromide; 1-[(2β,3α,5α,16β,17β)-3,17-Dihydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide. Grades: > 95%. CAS No. 119302-86-2. Molecular formula: C30H51N2O3.Br. Mole weight: 567.65. | |
| Rocuronium EP Impurity E | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 2-Pyrrolidinyl Desmorpholinylrocuronium Bromide; 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-65-7. Molecular formula: C32H53N2O3. Br. Mole weight: 593.69. | |
| Rocuronium EP Impurity G | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol; (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3,17-diol; Desacetyl Desallyl Rocuronium. Grades: 99 %. CAS No. 119302-20-4. Molecular formula: C27H46N2O3. Mole weight: 446.68. | |
| Rocuronium EP Impurity H | An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Alternative Names: 1,2-Dehydro-3-oxo Rocuronium Bromide; Rocuronium Bromide Impurity 21; 1-[(5α,16β,17β)-17-(Acetyloxy)-2-(4-morpholinyl)-3-oxoandrost-1-en-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. Grades: > 95%. CAS No. 1190105-67-9. Molecular formula: C32H49N2O4.Br. Mole weight: 605.65. | |
| Rocuronium Impurity11 | Rocuronium Impurity11. Uses: For analytical and research use. Molecular formula: C35H57BrN2O4. Mole weight: 649.76. Catalog: APB09617. | |
| Rocuronium Impurity12 | Rocuronium Impurity12. Uses: For analytical and research use. Molecular formula: C32H53BrN2O4. Mole weight: 609.69. Catalog: APB09618. | |
| Rodaplutin | Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Alternative Names: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6. | |
| R-(-)-O-Desmethyl venlafaxine | R-(-)-O-Desmethyl venlafaxine. Group: Biochemicals. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. Grades: Highly Purified. CAS No. 142761-11-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H25NO2. US Biological Life Sciences. |  Worldwide |
| R-(-)-O-Desmethyl-Venlafaxine | R-(-)-O-Desmethyl-Venlafaxine is a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. CAS No. 142761-11-3. Molecular formula: C16H25NO2. Mole weight: 263.38. | |
| R-(-)-O-Desmethyl Venlafaxine-[d6] | R-(-)-O-Desmethyl-Venlafaxine-[d6] is the labelled analogue of R-(-)-O-Desmethyl-Venlafaxine, a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Alternative Names: (R)-4-(2-(bis(methyl-d3)amino)-1-(1-hydroxycyclohexyl)ethyl)pheno. Grades: 98%. CAS No. 1062609-96-4. Molecular formula: C16H19D6NO2. Mole weight: 269.37. | |
| Roemerine | Roemerine is found in the leaves of Nelumbo nucifera, which has some anti-prostate cancer effect and alleviates adverse reactions in paclitaxel combination administration. Alternative Names: Remerine; Aporheine. Grades: > 95%. CAS No. 548-08-3. Molecular formula: C18H17NO2. Mole weight: 279.33. | |
| Rofapitide tetraxetan | Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-147057. |  |
| Rofecoxib | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-1g. Molecular Weight 314.36. See USA prepack pricing. |  |
| Rofecoxib | Rofecoxib is a COX-2 inhibitor (IC50s = 26 nM and > 50 μM in human osteosarcoma cells). Uses: Cyclooxygenase 2 inhibitors. Alternative Names: MK966; MK966; MK 966; MK0966; MK0966; MK 0966; Rofecoxib; brand name: Vioxx; Ceoxx; Ceeoxx. 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone. Grades: > 95%. CAS No. 162011-90-7. Molecular formula: C17H14O4S. Mole weight: 314.4. | |
| Rofecoxib | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-100mg. Molecular Weight 314.36. See USA prepack pricing. | |
| Rofecoxib | Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-17372. | |
| Roflumilast | Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Category: Active pharmaceutical ingredients. CAS No. 162401-32-3. Product ID: API162401323. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.21. |  |
| Roflumilast | Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy. Alternative Names: BY217; BY-217; BY 217; B 9302-107; B9302-107; B-9302-107; BYK 20869; BYK-20869; BYK20869; Daxas; Daliresp. Grades: 99%. CAS No. 162401-32-3. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.207. | |
| Roflumilast | Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDE4A4, PDE4B1, and PDE4B2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15455. | |
| Roflumilast | Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences. | Worldwide |
| Roflumilast-d4 | Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast Impurity 1 | Roflumilast Impurity 1. Uses: For analytical and research use. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. Catalog: APB292135785. | |
| Roflumilast Impurity 2 | Roflumilast Impurity 2. Uses: For analytical and research use. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.41. Catalog: APB1352122372. | |
| Roflumilast Impurity 3 | Roflumilast Impurity 3. Uses: For analytical and research use. CAS No. 1391053-75-0. Molecular formula: C17H15ClF2N2O3. Mole weight: 368.76. Catalog: APB1391053750. | |
| Roflumilast Impurity 4 | Roflumilast Impurity 4. Uses: For analytical and research use. Molecular formula: C16H10F2O8. Mole weight: 368.24. Catalog: APB12076. | |
| Roflumilast Impurity D | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: Benzoic acid, 3-(cyclopropylmethoxy)-4-hydroxy-. CAS No. 1243391-44-7. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Roflumilast Impurity E | Roflumilast Impurity E is an impurity of Roflumilast, which acts as a selective and long-acting enzyme PDE-4 inhibitor (IC50 value of 0.8 nM). Category: Active pharmaceutical ingredients. CAS No. 1391052-76-8. Product ID: API1391052768. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. | |
| Roflumilast N-oxide | Roflumilast N-oxide is a PDE type 4 inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 292135-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100639. | |
| Roflumilast N-oxide | Roflumilast N-oxide is an inhibitor of PDE type 4. Category: Active pharmaceutical ingredients. CAS No. 292135-78-5. Product ID: API292135785. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast N-Oxide | Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast N-Oxide | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl- methoxybenzamide; 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide. Grades: > 95%. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast Related Compound A | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as an antiasthmatic agent. Alternative Names: 4-O-Des(difluoromethyl) Roflumilast; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: > 95%. CAS No. 475271-62-6. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.20. | |
| Roflumilast Related Compound B | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: 3-O-Decyclopropyl Roflumilast; Roflumilast metabolite M05; 3-(Hydroxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. CAS No. 1391052-76-8. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.11. | |
| Roflumilast Related Compound D | An impurity and intermediate in the preparation of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Alternative Names: 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid; Benzoic acid, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-. Grades: 98%. CAS No. 162401-62-9. Molecular formula: C12H12F2O4. Mole weight: 258.22. | |
| Roflupram | Roflupram is a selective, orally active and brain-penetrant PDE4 inhibitor, with an IC50 of 26.2 nM for core catalytic domains of human PDE4. Roflupram can reverse cognitive deficits and reduce the production of pro-inflammatory factors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093412-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115383. | |
| Roflurane | Roflurane is a halocarbon drug. It has been investigated as an inhalational anesthetic. Category: Active pharmaceutical ingredients. Synonyms: DA-893. CAS No. 679-90-3. Product ID: API679903. Molecular formula: C3H4BrF3O. Mole weight: 192.96. | |
| Rogaratinib | Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Alternative Names: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Molecular formula: C23H26N6O3S. Mole weight: 466.6. | |
| Roginolisib | Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827. | |
| Rogocekib | Rogocekib is an orally effective CLK 2 inhibitor, with an IC50 of 1.4 nM, showing anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CTX-712. CAS No. 2144751-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144875. | |
| Rohinitib | Rohinitib is a potent and specific eIF4A inhibitor. Rohinitib induces cell apoptosis of acute myeloid leukemia (AML) cell lines and reduces the leukemia burden of AML xenograft model. Rohinitib can be used for the research of AML[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1139253-73-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148422. | |
| Rolapitant | Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751. | |
| Rolapitant | Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 552292-08-7. Product ID: API552292087. Molecular formula: C25H26F6N2O2. Mole weight: 500.48. | |
| Rolapitant | Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Alternative Names: (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. | |
| Rolapitant hydrochloride | Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models. Category: Active pharmaceutical ingredients. CAS No. 858102-79-1. Product ID: API858102791. Molecular formula: C25H27ClF6N2O2. Mole weight: 536.94. | |
| Rolapitant hydrochloride hydrate | Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 914462-92-3. Product ID: API914462923. Molecular formula: C25H29ClF6N2O3. Mole weight: 554.95. | |
| Rolapitant Impurity 1 | Rolapitant Impurity 1. Uses: For analytical and research use. Molecular formula: C25H22D4F6N2O2. Mole weight: 504.51. Catalog: APB11169. | |
| Rolapitant Impurity 2 | Rolapitant Impurity 2. Uses: For analytical and research use. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741260. | |
| Rolapitant Impurity 3 | Rolapitant Impurity 3. Uses: For analytical and research use. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741259. | |
| Rolapitant Impurity 4 | Rolapitant Impurity 4. Uses: For analytical and research use. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB552292736. | |
| Rolapitant Impurity 5 | Rolapitant Impurity 5. Uses: For analytical and research use. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741306. | |
| Rolapitant Impurity 6 | Rolapitant Impurity 6. Uses: For analytical and research use. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741282. | |
| Rolapitant Impurity 7 | Rolapitant Impurity 7. Uses: For analytical and research use. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741293. | |
| Rolapitant Impurity 8 | Rolapitant Impurity 8. Uses: For analytical and research use. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741271. | |
| Roledumab | Roledumab (LFB-R593) is a human IgG1-κ antibody targeting RHD/CD240D. Roledumab is expressed by YB2/0 rat hybridoma cells[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: LFB-R593. CAS No. 1174008-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99880. | |
| Rolipram | Rolipram is a PDE4 inhibitor, with blood-brain barrier permeability, that reverses β-amyloid-induced learning and memory impairment in rats. Rolipram elevates intracellular cAMP and clevels and regulates the cAMP/CREB signaling pathway, thereby alleviating neuroinflammation and apoptotic responses. Rolipram promotes neuronal differentiation of human bone marrow mesenchymal stem cells and inhibits Methamphetamine- and morphine-induced hyperlocomotion in mice. Rolipram also reduces the viability of glioblastoma stem-like cells and enhances Bevacizumab (HY-P9906)-induced cell death. Rolipram inhibits the expression of proinflammatory cytokines and enhances central noradrenergic transmission. Rolipram is mainly used in studies related to various central nervous system diseases including Alzheimer's disease, major depressive disorder, glioblastoma multiforme, and multiple sclerosis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900. | |
| Rolipram | Rolipram. Group: Biochemicals. Grades: Purified. CAS No. 61413-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Rolipram (4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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