A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [RAS(ON)] state of KRASG12C[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2641993-55-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141477.
RMAD-5
RMAD-5 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 5; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Phe-Ser-Leu-Cys-Cys-Arg. Molecular formula: C155H246N58O43S6. Mole weight: 3802.35.
RMAD-7
RMAD-7 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 7; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Ser-Ser-Leu-Cys-Cys-Ar. Molecular formula: C149H242N58O44S6. Mole weight: 3742.26.
R-(-)-Manidipine
R-(-)-Manidipine. Group: Biochemicals. Alternative Names: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester; (-)-Manidipine. Grades: Highly Purified. CAS No. 133082-19-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C35H38N4O6. US Biological Life Sciences.
Worldwide
R-(-)-Manidipine-[d4]
R-(-)-Manidipine-[d4] is the labelled (R)-enantiomer of Manidipine. Manidipine is a dihydropyridine calcium channel blocker used as an antihypertensive. Synonyms: R-(-)-Manidipine D4; (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl-d4 Methyl Ester; (-)-Manidipine-d4. Grade: >95%. CAS No. 1217718-54-1. Molecular formula: C35H34D4N4O6. Mole weight: 614.72.
RMC-4550
RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2172651-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116009.
RMC-4627
RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250059-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143510.
RMC-4998
RMC-4998 is an orally active inhibitor targeting the active or GTP-bound state of the KRASG12C mutant. RMC-4998 can form a ternary complex with intracellular CYPA and the activated KRASG12C mutant, with an IC50 value of 28 nM. RMC-4998 can inhibit ERK signaling in KRASG12C mutant cancer cells and induce apoptosis. RMC-4998 can be used for tumor research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2642037-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156671.
RMC-5127
RMC-5127 is a small molecule inhibitor that binds to GTP-targeted KRASG12V, with oral bioavailability and blood-brain barrier permeability. RMC-5127 inhibits the activities of the RAS and MAPK pathways, suppresses the proliferation of KRASG12V-mutant cancer cells and induces their apoptosis. RMC-5127 can be used for the research of KRASG12V-mutant non-small cell lung cancer, pancreatic ductal adenocarcinoma, colorectal cancer and intracranial KRASG12V tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3082166-76-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173629.
RMC-5552
RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2382768-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132168.
RMC-6272
RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RM-006. CAS No. 2382769-46-0. Pack Sizes: 1 mg; 10 mg. Product ID: HY-134904.
RMC-7977
RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (Kd = 195 nM) and KRAS (G12V) (Kd = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK, CRAF, and RSK, as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRASG12C cancer models, and demonstrates good tolerability across various RAS cancer models[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2765082-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-156498.
RMC-7977
RMC-7977 is a potent, reversible, tri-complex oral inhibitor that selectively targets active (GTP-bound) forms of KRAS, HRAS, and NRAS, which exhibits broad-spectrum activity against both mutant and wild-type variants (a RASMULTI (ON) inhibitor). It also exhibits significant anti-tumor efficacy in pancreatic ductal adenocarcinoma (PDAC). Group: Inhibitors. CAS No. 2765082-12-8. Pack Sizes: 1mg. Product ID: E1858. Formula: C47H60N8O6S.
United States; Europe
r-(-)-Mecamylamine hydrochloride
r-(-)-Mecamylamine hydrochloride. Alternative Names: (1S,2R,4R)-. CAS No. 107596-31-6. Product ID: ACM107596316. Molecular formula: C11H22ClN. Mole weight: 203.75. Alfa Chemistry - ISO 9001:32057 Certified.
R-(-)-Mecamylamine Hydrochloride
The R-(+) enantiomer of Mecamylamine , a noncompetitive neuronal nicotinic receptor modulator. Group: Biochemicals. Alternative Names: (1S,2R,4R)-. Grades: Highly Purified. CAS No. 107596-31-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
R(+)-Methylindazone
R(+)-Methylindazone (R(+)-IAA-94) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-Methylindazone inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R(+)-IAA-94. CAS No. 54197-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12693.
R-Mevalonic Acid
R-Mevalonic Acid, can stimulate leukemic cells from some patients with B cell chronic lymphocytic leukemia (CLL) to enter the cell cycle in vitro and to synthesize DNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 17817-88-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H12O4, Molecular Weight: 148.16. US Biological Life Sciences.
Worldwide
R-Mevalonic Acid, Lithium Salt
Mevalonic acid is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders, R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis. Group: Biochemicals. Alternative Names: Lithium (R)-3,5-dihydroxy-3-methylpentanoate, Lithium (R)-3,5-dihydroxy-3-methylvalerate, R-MVA-Li. Grades: Highly Purified. CAS No. 1255502-07-8. Pack Sizes: 10mg. Molecular Formula: C6H11LiO4, Molecular Weight: 154.09. US Biological Life Sciences.
Worldwide
R-(-)-Mexiletine hydrochloride
R-(-)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2R)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (-)-(R)-Mexiletine hydrochloride; (-)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-86-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences.
Worldwide
RN 1734
RN 1734. Group: Biochemicals. Grades: Purified. CAS No. 946387-07-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RN 1747
RN 1747. Group: Biochemicals. Grades: Purified. CAS No. 1024448-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RN-1747
RN-1747 is a selective TRPV4 channel agonist, with EC50 values of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 acts as an antagonist of TRPM8, with an IC50 of 4 μM. Topical cutaneous administration of RN-1747 induces hypothermia, increases tail heat loss via cutaneous vasodilation, and promotes cold-seeking behavior in rats. Intracerebroventricular administration of RN-1747 does not induce hypothermia in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1024448-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19976.
RN 1 dihydrochloride
RN 1 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RN-1 dihydrochloride
RN-1 dihydrochloride is a potent, brain-penetrant, irreversible and selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 70 nM. RN-1 dihydrochloride exhibits selectivity for LSD1 over MAO-A and MAO-B with IC50 values of 0.51 μM and 2.785 μM respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1781835-13-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110130.
RN2PA_RANPI Ranatuerin-2Pa precursor
RN2PA_RANPI Ranatuerin-2Pa precursor is an antibacterial peptide isolated from Rana pipiens. Synonyms: Gly-Phe-Leu-Ser-Thr-Val-Lys-Asn-Leu-Ala-Thr-Asn-Val-Ala-Gly-Thr-Val-Ile-Asp-Thr-Ile-Lys-Cys-Lys-Val-Thr-Gly-Gly-Cys.
RNA 3'-terminal-phosphate cyclase (ATP)
Adenosine 5'-(γ-thio)triphosphate can act instead of ATP. cf. EC 6.5.1.5, RNA-3'-phosphate cyclase (GTP). Group: Enzymes. Synonyms: RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Enzyme Commission Number: EC 6.5.1.4. CAS No. 85638-41-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5823; RNA 3'-terminal-phosphate cyclase (ATP); EC 6.5.1.4; 85638-41-1; RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Cat No: EXWM-5823.
RNA 3'-terminal-phosphate cyclase (GTP)
The enzyme from the archaeon Pyrococcus furiosus is activated by Mg2+. cf. EC 6.5.1.4, RNA-3'-phosphate cyclase (ATP). Group: Enzymes. Synonyms: Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Enzyme Commission Number: EC 6.5.1.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5824; RNA 3'-terminal-phosphate cyclase (GTP); EC 6.5.1.5; Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Cat No: EXWM-5824.
RNA-directed DNA polymerase
Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. RT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3261; RNA-directed DNA polymerase; EC 2.7.7.49; 9068-38-6; DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Cat No: EXWM-3261.
RNA-directed RNA polymerase
Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase. Group: Enzymes. Synonyms: RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonuclei. Enzyme Commission Number: EC 2.7.7.48. CAS No. 9026-28-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3260; RNA-directed RNA polymerase; EC 2.7.7.48; 9026-28-2; RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonucleic acid replicase; ribonucleic acid-dependent ribonucleate nucleotidyltransferase; ribonucleic acid-dependent ribonucleic acid polymerase; ribonucleic replicase; ribonucleic synthetase; RNA replicase; RNA synthetase; RNA transcriptase; RNA-dependent ribonucleate nucleotidyltransferase; RDRP; RNA-dependent RNA polymerase; RNA-dependent RNA replicase; transcriptase. Cat No: EXWM-3260.
RNA helicase
RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.12 (DNA helicase). Group: Enzymes. Synonyms: CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Enzyme Commission Number: EC 3.6.4.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4703; RNA helicase; EC 3.6.4.13; CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Cat No: EXWM-4703.
RNAIII-inhibiting peptide
RNAIII-inhibiting peptide, a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide; L-Phenylalaninamide, L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-; L-Tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-L-phenylalaninamide; RNAIII-inhibiting peptide (synthetic). Grade: ≥95%. CAS No. 661485-29-6. Molecular formula: C45H56N10O11. Mole weight: 912.99.
RNAIII-inhibiting peptideTFA
RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis. Uses: Scientific research. Category: Signaling pathways. CAS No. 2703745-76-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1452A.
RNAIII-inhibiting peptide TFA
RNAIII-inhibiting peptide (TFA), a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2.TFA; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide trifluoroacetic acid; RNAIII-inhibiting peptide trifluoroacetic acid; RNAIII-inhibiting peptide (TFA). Grade: >98%. CAS No. 2703745-76-8. Molecular formula: C45H56N10O11.C2HF3O2. Mole weight: 1027.01.
RNA ligase (ATP)
The enzyme catalyses the ligation of RNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of single-strand breaks in RNA. Catalysis occurs by a three-step mechanism, starting with the activation of the enzyme by ATP, forming a phosphoramide bond between adenylate and a lysine residue. The adenylate group is then transferred to the 5'-phosphate terminus of the substrate, forming the capped structure 5'-(5'-diphosphoadenosine)-[RNA]. Finally, the enzyme catalyses a nucleophilic attack of the 3'-OH terminus on the capped terminus, which results in formation of the phosphodiester bond and release of the adenylate. Group: Enzymes. Synonyms: polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Enzyme Commission Number: EC 6.5.1.3. CAS No. 37353-39-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5822; RNA ligase (ATP); EC 6.5.1.3; 37353-39-2; polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Cat No: EXWM-5822.
RNA Ligase T4, 10-20u/ul, 10X Buffer
RNA Ligase T4, 10-20u/ul, 10X Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
RNA Ligase T4, 10-20u/ul, ATP Buffer
RNA Ligase T4, 10-20u/ul, ATP Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
RNA Ligase T4, 10-20u/ul, BSA Buffer
RNA Ligase T4, 10-20u/ul, BSA Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
RNase A, Bovine pancreas
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ribonuclease A; EC 4.6.1.18; RNase A. CAS No. 9001-99-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-129046.
RNase A, Recombinant (animal free)
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A, Recombinant (animal free) is recombinant RNase A with no animal-derived components[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-99-4. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-129046I.
RNase B Glycoprotein Standard from bovine pancreas
RNase B Glycoprotein Standard from bovine pancreas. Uses: For analytical and research use. CAS No. 9001-99-4. EC Number: 232-646-6. Catalog: AP9001994-B.
RNase H
RNase H. Ribonuclease h (rnase h) specifically degrades the rna strand in rna-dna hybrids. it does not hydrolyze the phosphodiester bonds within single-stranded and double-stranded dna and rna. this product is purified from e. coli expressing the recombinant rnha gene on a plasmid with 17 kda molecular weight and it can be inactivated by heating at 65°c for 20 minutes. Group: DNA Modifying Enzymes. Purity: 100U; 5*100KU. Storage: Store at -20°C. Cat No: ME-4003.
RNase L-IN-2
RNase L-IN-2 (compound 2) is an activtor of RNase L with EC50 value of 22 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 357618-26-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121834.
RNA splicing modulator 1
RNA splicing modulator 1 (compound 233) is a RNA splicing modulator, with an AC50 value of <100 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2726461-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150246.
The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer. Group: Enzymes. Synonyms: terminal uridylyltransferase; TUT. Enzyme Commission Number: EC 2.7.7.52. CAS No. 78519-53-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3265; RNA uridylyltransferase; EC 2.7.7.52; 78519-53-6; terminal uridylyltransferase; TUT. Cat No: EXWM-3265.
An anticonvulsant, hypnotic. A metabolite of Mephentoin. Group: Biochemicals. Alternative Names: R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
RNF114 ligand 1
RNF114 ligand 1 is an E3 Ubiquitin ligase RNF114 ligand[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 900137-36-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156499.
R-(-)-Norapomorphine hydrochloride
R-(-)-Norapomorphine hydrochloride. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride; 6a-b-Noraporphine-10,11-diol hydrochloride; (-)-Norapomorphine hydrochloride. Grades: Highly Purified. CAS No. 420382-69-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H16ClNO2. US Biological Life Sciences.
Worldwide
RNPA1000
RNPA1000, an antibiotic, is a potent RnpA inhibitor and inhibits RnpA-mediated cellular RNA degradation. RNPA1000 inhibits tRNA maturation with an IC50 of 175 μM. RNPA1000 displays broad-spectrum antimicrobial activities and inhibits staphylococcal and all Gram-positive bacterial pathogens activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 359600-10-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-12824.
RNS peptide
RNS peptide is a randomly scrambled control peptide that can be used as a negative control for MANS peptide (HY-P10218)[1]. Uses: Scientific research. Category: Peptides. CAS No. 901117-08-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10776.
Ro 01-6128
Ro 01-6128. Group: Biochemicals. Grades: Purified. CAS No. 302841-86-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 0437626
Ro 0437626. Group: Biochemicals. Grades: Purified. CAS No. 134362-79-1. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
Worldwide
Ro 04-5595 hydrochloride
Ro 04-5595 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64047-73-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 04-6790
Ro 04-6790. Group: Biochemicals. Grades: Purified. CAS No. 202466-68-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 08-2750
Ro 08-2750. Group: Biochemicals. Grades: Purified. CAS No. 37854-59-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 08-2750
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA[1]. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37854-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108466.
Ro 09-1679
Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61.
Ro 10-5824 dihydrochloride
Ro 10-5824 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 189744-94-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 106-9920
Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Group: Biochemicals. Alternative Names: 6- (Phenylsulfinyl) tetrazolo[1, 5-b]pyridazine. Grades: Highly Purified. CAS No. 62645-28-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
RO1138452
RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAY10441. CAS No. 221529-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108912.
Ro 1138452 hydrochloride
Ro 1138452 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 15-4513
Ro 15-4513. Group: Biochemicals. Grades: Purified. CAS No. 91917-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro15-4513
Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR)[1]. Ro15-4513 is a potent ethanol antagonist[2]. Ro15-4513 has anti-anxiety effect[3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 91917-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103476.
Ro 19-4603
Ro 19-4603. Group: Biochemicals. Grades: Purified. CAS No. 99632-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ro 19-7728
Ro 19-7728 is a metabolite of fleroxacin. Category: Active pharmaceutical ingredients. CAS No. 104638-13-3. Product ID: API104638133. Molecular formula: C17H18F3N3O4. Mole weight: 385.343.
Ro 20-1724
Ro 20-1724. Group: Biochemicals. Grades: Purified. CAS No. 29925-17-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Ro 20-1724
Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 20-174. CAS No. 29925-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100927.