American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
RM-018 RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [“RAS(ON)”] state of KRASG12C[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2641993-55-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141477. MedChemExpress MCE
RMAD-5 RMAD-5 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 5; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Phe-Ser-Leu-Cys-Cys-Arg. Molecular formula: C155H246N58O43S6. Mole weight: 3802.35. BOC Sciences 11
RMAD-7 RMAD-7 is an antibacterial peptide isolated from Macaca mulatta (Rhesus monkey). It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Neutrophil defensin 7; Arg-Thr-Cys-Arg-Cys-Arg-Phe-Gly-Arg-Cys-Phe-Arg-Arg-Glu-Ser-Tyr-Ser-Gly-Ser-Cys-Asn-Ile-Asn-Gly-Arg-Ile-Ser-Ser-Leu-Cys-Cys-Ar. Molecular formula: C149H242N58O44S6. Mole weight: 3742.26. BOC Sciences 11
R-(-)-Manidipine R-(-)-Manidipine. Group: Biochemicals. Alternative Names: (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester; (-)-Manidipine. Grades: Highly Purified. CAS No. 133082-19-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C35H38N4O6. US Biological Life Sciences. USBiological 7
Worldwide
R-(-)-Manidipine-[d4] R-(-)-Manidipine-[d4] is the labelled (R)-enantiomer of Manidipine. Manidipine is a dihydropyridine calcium channel blocker used as an antihypertensive. Synonyms: R-(-)-Manidipine D4; (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl-d4 Methyl Ester; (-)-Manidipine-d4. Grade: >95%. CAS No. 1217718-54-1. Molecular formula: C35H34D4N4O6. Mole weight: 614.72. BOC Sciences 2
RMC-4550 RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2172651-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116009. MedChemExpress MCE
RMC-4627 RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250059-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143510. MedChemExpress MCE
RMC-4998 RMC-4998 is an orally active inhibitor targeting the active or GTP-bound state of the KRASG12C mutant. RMC-4998 can form a ternary complex with intracellular CYPA and the activated KRASG12C mutant, with an IC50 value of 28 nM. RMC-4998 can inhibit ERK signaling in KRASG12C mutant cancer cells and induce apoptosis. RMC-4998 can be used for tumor research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2642037-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156671. MedChemExpress MCE
RMC-5127 RMC-5127 is a small molecule inhibitor that binds to GTP-targeted KRASG12V, with oral bioavailability and blood-brain barrier permeability. RMC-5127 inhibits the activities of the RAS and MAPK pathways, suppresses the proliferation of KRASG12V-mutant cancer cells and induces their apoptosis. RMC-5127 can be used for the research of KRASG12V-mutant non-small cell lung cancer, pancreatic ductal adenocarcinoma, colorectal cancer and intracranial KRASG12V tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3082166-76-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173629. MedChemExpress MCE
RMC-5552 RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2382768-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132168. MedChemExpress MCE
RMC-6272 RMC-6272 (RM-006) is a bi-steric mTORC1-selective inhibitor. RMC-6272 exhibits potent and selective (> 10-fold) inhibition of mTORC1 over mTORC2. RMC-6272 shows improved inhibition of mTORC1 in comparison to Rapamycin, and induces more cell death in TSC2 null tumors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RM-006. CAS No. 2382769-46-0. Pack Sizes: 1 mg; 10 mg. Product ID: HY-134904. MedChemExpress MCE
RMC-7977 RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (Kd = 195 nM) and KRAS (G12V) (Kd = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK, CRAF, and RSK, as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRASG12C cancer models, and demonstrates good tolerability across various RAS cancer models[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2765082-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-156498. MedChemExpress MCE
RMC-7977 RMC-7977 is a potent, reversible, tri-complex oral inhibitor that selectively targets active (GTP-bound) forms of KRAS, HRAS, and NRAS, which exhibits broad-spectrum activity against both mutant and wild-type variants (a RASMULTI (ON) inhibitor). It also exhibits significant anti-tumor efficacy in pancreatic ductal adenocarcinoma (PDAC). Group: Inhibitors. CAS No. 2765082-12-8. Pack Sizes: 1mg. Product ID: E1858. Formula: C47H60N8O6S. Selleck Chemicals
United States; Europe
r-(-)-Mecamylamine hydrochloride r-(-)-Mecamylamine hydrochloride. Alternative Names: (1S,2R,4R)-. CAS No. 107596-31-6. Product ID: ACM107596316. Molecular formula: C11H22ClN. Mole weight: 203.75. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 2
R-(-)-Mecamylamine Hydrochloride The R-(+) enantiomer of Mecamylamine , a noncompetitive neuronal nicotinic receptor modulator. Group: Biochemicals. Alternative Names: (1S,2R,4R)-. Grades: Highly Purified. CAS No. 107596-31-6. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
R(+)-Methylindazone R(+)-Methylindazone (R(+)-IAA-94) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-Methylindazone inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R(+)-IAA-94. CAS No. 54197-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12693. MedChemExpress MCE
R-Mevalonic Acid R-Mevalonic Acid, can stimulate leukemic cells from some patients with B cell chronic lymphocytic leukemia (CLL) to enter the cell cycle in vitro and to synthesize DNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 17817-88-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H12O4, Molecular Weight: 148.16. US Biological Life Sciences. USBiological 2
Worldwide
R-Mevalonic Acid, Lithium Salt Mevalonic acid is an intermediate in the mevalonate pathway, producing terpenes and steroids. This function provides treatment options metabolic disorders, R-mevalonate accumulates in patients with the autosomal recessively inherited mevalonic acidurias, an inborn error of cholesterol and nonsterol isoprene biosynthesis. Group: Biochemicals. Alternative Names: Lithium (R)-3,5-dihydroxy-3-methylpentanoate, Lithium (R)-3,5-dihydroxy-3-methylvalerate, R-MVA-Li. Grades: Highly Purified. CAS No. 1255502-07-8. Pack Sizes: 10mg. Molecular Formula: C6H11LiO4, Molecular Weight: 154.09. US Biological Life Sciences. USBiological 3
Worldwide
R-(-)-Mexiletine hydrochloride R-(-)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2R)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (-)-(R)-Mexiletine hydrochloride; (-)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-86-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences. USBiological 8
Worldwide
RN 1734 RN 1734. Group: Biochemicals. Grades: Purified. CAS No. 946387-07-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
RN 1747 RN 1747. Group: Biochemicals. Grades: Purified. CAS No. 1024448-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
RN-1747 RN-1747 is a selective TRPV4 channel agonist, with EC50 values of 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4, respectively. RN-1747 acts as an antagonist of TRPM8, with an IC50 of 4 μM. Topical cutaneous administration of RN-1747 induces hypothermia, increases tail heat loss via cutaneous vasodilation, and promotes cold-seeking behavior in rats. Intracerebroventricular administration of RN-1747 does not induce hypothermia in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1024448-59-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19976. MedChemExpress MCE
RN 1 dihydrochloride RN 1 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
RN-1 dihydrochloride RN-1 dihydrochloride is a potent, brain-penetrant, irreversible and selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC50 of 70 nM. RN-1 dihydrochloride exhibits selectivity for LSD1 over MAO-A and MAO-B with IC50 values of 0.51 μM and 2.785 μM respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1781835-13-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110130. MedChemExpress MCE
RN2PA_RANPI Ranatuerin-2Pa precursor RN2PA_RANPI Ranatuerin-2Pa precursor is an antibacterial peptide isolated from Rana pipiens. Synonyms: Gly-Phe-Leu-Ser-Thr-Val-Lys-Asn-Leu-Ala-Thr-Asn-Val-Ala-Gly-Thr-Val-Ile-Asp-Thr-Ile-Lys-Cys-Lys-Val-Thr-Gly-Gly-Cys. BOC Sciences 11
RNA 3'-terminal-phosphate cyclase (ATP) Adenosine 5'-(γ-thio)triphosphate can act instead of ATP. cf. EC 6.5.1.5, RNA-3'-phosphate cyclase (GTP). Group: Enzymes. Synonyms: RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Enzyme Commission Number: EC 6.5.1.4. CAS No. 85638-41-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5823; RNA 3'-terminal-phosphate cyclase (ATP); EC 6.5.1.4; 85638-41-1; RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Cat No: EXWM-5823. Creative Enzymes
RNA 3'-terminal-phosphate cyclase (GTP) The enzyme from the archaeon Pyrococcus furiosus is activated by Mg2+. cf. EC 6.5.1.4, RNA-3'-phosphate cyclase (ATP). Group: Enzymes. Synonyms: Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Enzyme Commission Number: EC 6.5.1.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5824; RNA 3'-terminal-phosphate cyclase (GTP); EC 6.5.1.5; Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Cat No: EXWM-5824. Creative Enzymes
RNA-directed DNA polymerase Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. RT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3261; RNA-directed DNA polymerase; EC 2.7.7.49; 9068-38-6; DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Cat No: EXWM-3261. Creative Enzymes
RNA-directed RNA polymerase Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase. Group: Enzymes. Synonyms: RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonuclei. Enzyme Commission Number: EC 2.7.7.48. CAS No. 9026-28-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3260; RNA-directed RNA polymerase; EC 2.7.7.48; 9026-28-2; RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonucleic acid replicase; ribonucleic acid-dependent ribonucleate nucleotidyltransferase; ribonucleic acid-dependent ribonucleic acid polymerase; ribonucleic replicase; ribonucleic synthetase; RNA replicase; RNA synthetase; RNA transcriptase; RNA-dependent ribonucleate nucleotidyltransferase; RDRP; RNA-dependent RNA polymerase; RNA-dependent RNA replicase; transcriptase. Cat No: EXWM-3260. Creative Enzymes
RNA helicase RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. Some helicases unwind DNA as well as RNA. May be identical with EC 3.6.4.12 (DNA helicase). Group: Enzymes. Synonyms: CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Enzyme Commission Number: EC 3.6.4.13. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4703; RNA helicase; EC 3.6.4.13; CSFV NS3 helicase; DBP2; DbpA; DDX17; DDX25; DDX3; DDX3X; DDX3Y; DDX4; DDX5; DEAD-box protein DED1; DEAD-box RNA helicase; DEAH-box protein 2; DEAH-box RNA helicase; DED1; Dex(H/D) RNA helicase; EhDEAD1; EhDEAD1 RNA helicase; eIF4A helicase; KOKV helicase; Mtr4p; nonstructural protein 3 helicase; NPH-II; RHA; RNA helicase A; RNA helicase DDX3; RNA helicase Hera; RNA-dependent ATPase; TGBp1 NTPase/helicase domain; VRH1; GRTH/DDX25. Cat No: EXWM-4703. Creative Enzymes
RNAIII-inhibiting peptide RNAIII-inhibiting peptide, a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide; L-Phenylalaninamide, L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-; L-Tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-L-phenylalaninamide; RNAIII-inhibiting peptide (synthetic). Grade: ≥95%. CAS No. 661485-29-6. Molecular formula: C45H56N10O11. Mole weight: 912.99. BOC Sciences 11
RNAIII-inhibiting peptideTFA RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis. Uses: Scientific research. Category: Signaling pathways. CAS No. 2703745-76-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1452A. MedChemExpress MCE
RNAIII-inhibiting peptide TFA RNAIII-inhibiting peptide (TFA), a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2.TFA; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide trifluoroacetic acid; RNAIII-inhibiting peptide trifluoroacetic acid; RNAIII-inhibiting peptide (TFA). Grade: >98%. CAS No. 2703745-76-8. Molecular formula: C45H56N10O11.C2HF3O2. Mole weight: 1027.01. BOC Sciences 11
RNA ligase (ATP) The enzyme catalyses the ligation of RNA strands with 3'-hydroxyl and 5'-phosphate termini, forming a phosphodiester and sealing certain types of single-strand breaks in RNA. Catalysis occurs by a three-step mechanism, starting with the activation of the enzyme by ATP, forming a phosphoramide bond between adenylate and a lysine residue. The adenylate group is then transferred to the 5'-phosphate terminus of the substrate, forming the capped structure 5'-(5'-diphosphoadenosine)-[RNA]. Finally, the enzyme catalyses a nucleophilic attack of the 3'-OH terminus on the capped terminus, which results in formation of the phosphodiester bond and release of the adenylate. Group: Enzymes. Synonyms: polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Enzyme Commission Number: EC 6.5.1.3. CAS No. 37353-39-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5822; RNA ligase (ATP); EC 6.5.1.3; 37353-39-2; polyribonucleotide synthase (ATP); RNA ligase; polyribonucleotide ligase; ribonucleic ligase; poly(ribonucleotide): poly(ribonucleotide) ligase (AMP-forming). Cat No: EXWM-5822. Creative Enzymes
RNA Ligase T4, 10-20u/ul, 10X Buffer RNA Ligase T4, 10-20u/ul, 10X Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. USBiological 1
Worldwide
RNA Ligase T4, 10-20u/ul, ATP Buffer RNA Ligase T4, 10-20u/ul, ATP Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. USBiological 1
Worldwide
RNA Ligase T4, 10-20u/ul, BSA Buffer RNA Ligase T4, 10-20u/ul, BSA Buffer. Group: Molecular Biology. Alternative Names: Supplied with 10x Reaction Buffer, ATP and BSA Solutions. Grades: Molecular Biology Grade. Pack Sizes: 200ul. US Biological Life Sciences. USBiological 1
Worldwide
RNase A, Bovine pancreas RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ribonuclease A; EC 4.6.1.18; RNase A. CAS No. 9001-99-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-129046. MedChemExpress MCE
RNase A, Recombinant (animal free) RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A, Recombinant (animal free) is recombinant RNase A with no animal-derived components[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9001-99-4. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-129046I. MedChemExpress MCE
RNase B Glycoprotein Standard from bovine pancreas RNase B Glycoprotein Standard from bovine pancreas. Uses: For analytical and research use. CAS No. 9001-99-4. EC Number: 232-646-6. Catalog: AP9001994-B. Alfa Chemistry Analytical Products
RNase H RNase H. Ribonuclease h (rnase h) specifically degrades the rna strand in rna-dna hybrids. it does not hydrolyze the phosphodiester bonds within single-stranded and double-stranded dna and rna. this product is purified from e. coli expressing the recombinant rnha gene on a plasmid with 17 kda molecular weight and it can be inactivated by heating at 65°c for 20 minutes. Group: DNA Modifying Enzymes. Purity: 100U; 5*100KU. Storage: Store at -20°C. Cat No: ME-4003. Creative Enzymes
RNase L-IN-2 RNase L-IN-2 (compound 2) is an activtor of RNase L with EC50 value of 22 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 357618-26-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121834. MedChemExpress MCE
RNA splicing modulator 1 RNA splicing modulator 1 (compound 233) is a RNA splicing modulator, with an AC50 value of <100 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2726461-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150246. MedChemExpress MCE
RNA splicing modulator 3 RNA splicing modulator 3 is an RNA splicing modulator. RNA splicing modulator 3 modulates nucleic acid splicing, including pre-mRNA splicing[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2726461-43-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150248. MedChemExpress MCE
RNA uridylyltransferase The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer. Group: Enzymes. Synonyms: terminal uridylyltransferase; TUT. Enzyme Commission Number: EC 2.7.7.52. CAS No. 78519-53-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3265; RNA uridylyltransferase; EC 2.7.7.52; 78519-53-6; terminal uridylyltransferase; TUT. Cat No: EXWM-3265. Creative Enzymes
R)-(+)-N-Benzyl-1-phenylethylamine R)-(+)-N-Benzyl-1-phenylethylamine. Group: Biochemicals. Alternative Names: (α R) -α -Methyl-N- (phenylmethyl) benzenemethanamine; (+)-Benzylphenethylamine; (+)-N-Benzyl-1-phenylethylamine; (+)-N-Benzyl-α-phenylethylamine; (R)-(+)-N-Benzyl-α-methylbenzylamine; (R)-Benzyl(α-methylbenzyl)amine; (R)-N-(α-Methylbenzyl)-N-benzylamine; (R)-N-Benzyl-1-phenyl-1-ethylamine; (R)-N-Benzyl-1-phenylethanamine; (R)-N-Benzyl-1-phenylethylamine; (R)-N-Benzyl-N-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; Benzyl((R)-1-phenylethyl)amine; N-Benzyl((R)-1-phenylethyl)amine; N-Benzyl-(R)-α-methylbenzylamine; N- [ (R) -1-Phenylethyl] benzylamine. Grades: Highly Purified. CAS No. 38235-77-7. Pack Sizes: 1g. Molecular Formula: C15H17N, Molecular Weight: 211.3. US Biological Life Sciences. USBiological 3
Worldwide
R-(-)-N-Desmethyl mephenytoin R-(-)-N-Desmethyl mephenytoin. Group: Biochemicals. Alternative Names: R-(-)-Nirvanol, R-(-)-5-ethyl-5-phenylhydantoin. Grades: Highly Purified. CAS No. 65567-32-01. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H12N2O2. US Biological Life Sciences. USBiological 7
Worldwide
R-(-)-N-Desmethylmephenytoin (R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin) An anticonvulsant, hypnotic. A metabolite of Mephentoin. Group: Biochemicals. Alternative Names: R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 1
Worldwide
RNF114 ligand 1 RNF114 ligand 1 is an E3 Ubiquitin ligase RNF114 ligand[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 900137-36-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156499. MedChemExpress MCE
R-(-)-Norapomorphine hydrochloride R-(-)-Norapomorphine hydrochloride. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride; 6a-b-Noraporphine-10,11-diol hydrochloride; (-)-Norapomorphine hydrochloride. Grades: Highly Purified. CAS No. 420382-69-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H16ClNO2. US Biological Life Sciences. USBiological 8
Worldwide
RNPA1000 RNPA1000, an antibiotic, is a potent RnpA inhibitor and inhibits RnpA-mediated cellular RNA degradation. RNPA1000 inhibits tRNA maturation with an IC50 of 175 μM. RNPA1000 displays broad-spectrum antimicrobial activities and inhibits staphylococcal and all Gram-positive bacterial pathogens activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 359600-10-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-12824. MedChemExpress MCE
RNS peptide RNS peptide is a randomly scrambled control peptide that can be used as a negative control for MANS peptide (HY-P10218)[1]. Uses: Scientific research. Category: Peptides. CAS No. 901117-08-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10776. MedChemExpress MCE
Ro 01-6128 Ro 01-6128. Group: Biochemicals. Grades: Purified. CAS No. 302841-86-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 0437626 Ro 0437626. Group: Biochemicals. Grades: Purified. CAS No. 134362-79-1. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. USBiological 5
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Ro 04-5595 hydrochloride Ro 04-5595 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64047-73-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 04-6790 Ro 04-6790. Group: Biochemicals. Grades: Purified. CAS No. 202466-68-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 08-2750 Ro 08-2750. Group: Biochemicals. Grades: Purified. CAS No. 37854-59-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 08-2750 Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 μM. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA[1]. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 37854-59-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108466. MedChemExpress MCE
Ro 09-1679 Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61. BOC Sciences 12
Ro 10-5824 dihydrochloride Ro 10-5824 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 189744-94-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 106-9920 Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Group: Biochemicals. Alternative Names: 6- (Phenylsulfinyl) tetrazolo[1, 5-b]pyridazine. Grades: Highly Purified. CAS No. 62645-28-7. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
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RO1138452 RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAY10441. CAS No. 221529-58-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108912. MedChemExpress MCE
Ro 1138452 hydrochloride Ro 1138452 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 15-4513 Ro 15-4513. Group: Biochemicals. Grades: Purified. CAS No. 91917-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro15-4513 Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR)[1]. Ro15-4513 is a potent ethanol antagonist[2]. Ro15-4513 has anti-anxiety effect[3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 91917-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103476. MedChemExpress MCE
Ro 19-4603 Ro 19-4603. Group: Biochemicals. Grades: Purified. CAS No. 99632-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Ro 19-7728 Ro 19-7728 is a metabolite of fleroxacin. Category: Active pharmaceutical ingredients. CAS No. 104638-13-3. Product ID: API104638133. Molecular formula: C17H18F3N3O4. Mole weight: 385.343. Protheragen
Ro 20-1724 Ro 20-1724. Group: Biochemicals. Grades: Purified. CAS No. 29925-17-5. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Ro 20-1724 Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 20-174. CAS No. 29925-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100927. MedChemExpress MCE
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=2uM). Inhibits superoxide generation and arachidonic-induced platelet aggregation. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 4
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