A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Rolipram (Standard) is the analytical standard of Rolipram (HY-16900). This product is intended for research and analytical applications. Rolipram is a PDE4 inhibitor, with blood-brain barrier permeability, that reverses β-amyloid-induced learning and memory impairment in rats. Rolipram elevates intracellular cAMP and clevels and regulates the cAMP/CREB signaling pathway, thereby alleviating neuroinflammation and apoptotic responses. Rolipram promotes neuronal differentiation of human bone marrow mesenchymal stem cells and inhibits Methamphetamine- and morphine-induced hyperlocomotion in mice. Rolipram also reduces the viability of glioblastoma stem-like cells and enhances Bevacizumab (HY-P9906)-induced cell death. Rolipram inhibits the expression of proinflammatory cytokines and enhances central noradrenergic transmission. Rolipram is mainly used in studies related to various central nervous system diseases including Alzheimer's disease, major depressive disorder, glioblastoma multiforme, and multiple sclerosis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R,S)-Rolipram (Standard); (±)-Rolipram (Standard); ZK 62711 (Standard). CAS No. 61413-54-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16900R.
Rolistobart
Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2723442-10-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990092.
Rolitetracycline
Rolitetracycline is a semi-synthetic tetracycline antibiotic. It has broad-spectrum Gram-positive activity in the body. Uses: Antibacterial. Alternative Names: Reverin; Syntetrin; Rolitetraciclina; Rolitetracyclinum; Pyrrolidino-Methyl-Tetracycline. Grades: >98% by HPLC. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.56.
Rolitetracycline
Rolitetracycline is a highly soluble, broad-spectrum antibiotic derived from tetracycline. Rolitetracycline binds to and stabilizes bovine serum albumin, and also inhibits HIV-1 integrase, blocks Aβ fibril formation and suppresses dengue virus proliferation. Rolitetracycline mediates the inhibition of Aβ fibrils via a specific three-dimensional pharmacophore conformation, and exerts bacteriostatic and bactericidal activities. Rolitetracycline acts synergistically with Penicillin G (HY-N7139) or Cephalothin (HY-B1275A) to alter the effects on microbial growth. Rolitetracycline serves as an important tool compound for the study of bacterial infections (urinary tract infections, sepsis), HIV-1 and dengue virus infections, as well as Alzheimer's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 751-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-18257.
Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable. Group: Biochemicals. Alternative Names: (4S, 4aS, 5aS, 6S, 12aS) -4- (di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; 4- (Di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; Abricycline; Bristacin; N- (1-Pyrrolidinylmethyl) tetracycline; N- (Pyrrolidinomethyl) tetracycline; Pyrrolidinyl methyl tetracycline; Reverin; Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin; Transcycline; Velacycline. Grades: Technical Grade. CAS No. 751-97-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 527.57. US Biological Life Sciences.
Worldwide
Rolofylline
Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment.Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 (CYP450)[1].Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KW-3902. CAS No. 136199-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10965.
Romaciclib monohydrochloride
SEL120-34A monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8. SEL120-34A monohydrochloride weakly inhibits CDK9 (calculated IC50=1070 nM), but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. SEL120-34A monohydrochloride inhibits phosphorylation of STAT1 S727 and STAT5 S726[1]. Has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SEL120-34A monohydrochloride. CAS No. 2443816-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111388A.
Romandolide
Romandolide, an intriguing compound with the potential to attenuate inflammatory responses, displays promising therapeutic implications for conditions like rheumatoid arthritis and inflammatory bowel disease. Its mechanism of action remains under investigation, warranting further exploration into its pharmacological properties. Alternative Names: Acetic acid, 2-(1-oxopropoxy)-, 1-(3,3-dimethylcyclohexyl)ethyl ester; musk methyl propionate; 2-[1-(3,3-Dimethylcyclohexyl)ethoxy]-2-oxoethyl propionate; 1-(3,3-Dimethylcyclohexyl)ethyl 2-(1-oxopropoxy)acetate; Acetic acid, (1-oxopropoxy)-, 1-(3,3-dimethylcyclohexyl)ethyl ester; 1-(3,3-Dimethylcyclohexyl)ethyl 2-(1-oxopropoxy)acetate. Grades: ≥95%. CAS No. 236391-76-7. Molecular formula: C15H26O4. Mole weight: 270.36.
R-Omeprazole. Uses: For analytical and research use. CAS No. 161796-77-6. Mole weight: 367.40. Catalog: AP161796776.
Romidepsin
Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Uses: For research used only. Alternative Names: Istodax; FK228; FK 228; FK-228; Chromadax; Antibiotic FR 901228; FR901228; FR-901228; NSC-630176; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide. Grades: >98%. CAS No. 128517-07-7. Molecular formula: C24H36N4O6S2. Mole weight: 540.69.
Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively[1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FK 228; FR 901228; NSC 630176. CAS No. 128517-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15149.
Romidepsin
Romidepsin. Group: Biochemicals. Alternative Names: (1S,4Z,7S,10S,11E,20R)-4-Ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3, 6, 18, 21-tetrazabicyclo[8. 7. 6]tricos-11-ene-2, 5, 8, 19, 22-pentone; Depsipeptide; FK228. Grades: Highly Purified. CAS No. 128517-07-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H36N4O6S2. US Biological Life Sciences.
Worldwide
Romidepsin-[d7]
A labelled form of Romidepsin. Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Alternative Names: Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl]-D7 Cyclic (35)-Disulfide; [S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-L-valine (4-1)-Lactone-D7 Cyclic (12)-Disulfide; Antibiotic FR 901228-D7; Chromadax-D7; FK 228-D7; FR 901228-D7; NSC 630176-D7. Grades: >98%. Molecular formula: C24H29D7N4O6S2. Mole weight: 548.75.
Romidepsin (FK228)
Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228 / depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells. Group: Inhibitors. Alternative Names: FK228, Depsipeptide, FR 901228, NSC 630176. CAS No. 128517-07-7. Pack Sizes: 10mg. Product ID: S3020. Formula: C24H36N4O6S2. Smiles: CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Romifidine hydrochloride
Romifidine is an α2 agonist used as a sedative and analgesic in horses. Alternative Names: N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride; STH 2130Cl; Sedivet. CAS No. 65896-14-2. Molecular formula: C9H10BrClFN3. Mole weight: 294.55.
Romiplostim
Romiplostim is fusion protein thrombopoietin (TPO) peptide analog that regulates the number of platelets. Romiplostim has been used in the treatment of thrombocytopenia associated with chronic immune thrombocytopenia (ITP). CAS No. 267639-76-9. Molecular formula: C2634H4086N722O790S18. Mole weight: 59000.0 Da.
Romiplostim
Romiplostim is an Fc-peptide fusion protein mimetic of TPO (thrombopoietin protein) and also a c-Mpl agonist. Romiplostim binds to c-Mpl, stimulates megakaryocyte-mediated thrombopoiesis, and activates the same downstream signaling pathways as endogenous TPO. Romiplostim is applicable to research related to hematopoietic acute radiation syndrome and chronic immune thrombocytopenia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 267639-76-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990685.
Romosozumab
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Romosozumab binds to and inhibits sclerostin, promoting the activation of the Wnt/β-catenin pathway that normally stimulates osteoblasts. Alternative Names: Evenity. CAS No. 909395-70-6.
Romosozumab
Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: AMG-785; CDP-7851. CAS No. 909395-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9982.
Romurtide
Romurtide (Muroctasin) is a non-specific immune stimulant. Alternative Names: MDP-Lys (L18); muroctasin. CAS No. 78113-36-7. Molecular formula: C43H78N6O13. Mole weight: 887.11.
r-Ondansentron hydrochloride
r-Ondansentron hydrochloride. CAS No. 146844-89-5. Product ID: ACM146844895. Alfa Chemistry - ISO 9001:32057 Certified.
Rondonin
Rondonin is an antibacterial peptide isolated from Acanthoscurria rondoniae (Spider). It has activity against fungi. Alternative Names: Ile-Ile-Ile-Gln-Tyr-Glu-Gly-His-Lys-His. Grades: >96%. Molecular formula: C57H88N16O15. Mole weight: 1237.42.
Roniciclib
Roniciclib is an orally bioavailable pan-cyclin dependent kinase (CDK) inhibitor, with IC50s of 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7 and CDK9. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 1000394. CAS No. 1223498-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13914.
Roniciclib
Roniciclib, also known as BAY 1000394, is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. BAY1000394 selectively binds to and inhibits the activity of CDK1 / Cyclin B, CDK2 / Cyclin E, CDK4 / Cyclin D1, and CDK9 / Cyclin T1, serine / threonine kinases that play key roles in the regulation of the cell cycle progression and cellular proliferation. Alternative Names: BAY10-00394; BAY1000394; BAY 1000394; NSC774911; (2R,3R)-3-{[2-{[4-(S-Cyclopropylsulfonimidoyl)phenyl]amino}-5-(trifluoromethyl)-4-pyrimidinyl]oxy}-2-butanol; 2-Butanol, 3-[[2-[[4-(S-cyclopropylsulfonimidoyl)phenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]oxy]-, (2R,3R)-. Grades: ≥98%. CAS No. 1223498-69-8. Molecular formula: C18H21F3N4O3S. Mole weight: 430.44.
Ronidazole
Ronidazole is an antiprotozoal agent. Uses: Antiprotozoal agents. Alternative Names: 1-Methyl-5-nitro-1H-imidazole-2-methanol 2-Carbamate; (1-Methyl-5-nitroimidazol-2-yl)methyl Carbamate; 1-Methyl-2-carbamoyloxymethyl-5 -nitroimidazole; Dugro; MCMN; Ridzol; Ridzol P; Ridzole; Ronida BT. Grades: >98%. CAS No. 7681-76-7. Molecular formula: C6H8N4O4. Mole weight: 200.15.
Ronidazole
Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 7681-76-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-B0565.
Ronidazole
25g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C6H8N4O4. CAS No. 7681-76-7. Prepack ID 90026995-25g. Molecular Weight 200.15. See USA prepack pricing.
Ronidazole-[d3]
Ronidazole-[d3] is the labelled analogue of Ronidazole, which is an antimicrobial agent. Alternative Names: Ronidazole-D3; 2-Carbamoyloxymethyl-1-methyl-D3-5-nitro-1H-imidazole; 1-(Methyl-d3)-5-nitro-1H-imidazole-2-methanol 2-Carbamate; [1-(Methyl-d3)-5-nitroimidazol-2-yl]methyl Carbamate; 1-(Methyl-d3)-2-carbamoyl-oxymethyl-5-nitroimidazole; Dugro-d3; MCMN-d3; Ridzol-d3; Ridzol P-d3; Ridzole-d3; Ronida BT-d3. Grades: 95% by HPLC; 98% atom D. CAS No. 1015855-87-4. Molecular formula: C6H5D3N4O4. Mole weight: 203.17.
Ronopterin
Ronopterin is a potent Nitric oxide synthase inhibitor used as a neuroprotectant. Alternative Names: VAS-203; VAS 203; VAS203; Ronopterin; (1R,2S)-1-[(6R)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol; 4-aminotetrahydrobiopterin. Grades: >98%. CAS No. 206885-38-3. Molecular formula: C9H16N6O2. Mole weight: 240.27.
Rontalizumab
Rontalizumab is a humanized IgG1 monoclonal antibody targets IFN-α. Rontalizumab can be used for the research of systemic lupus erythematosus[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: RhuMab IFNalpha; Anti-Human IFN alpha Recombinant Antibody. CAS No. 948570-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99267.
Rooibos CO2 Extract
Rooibos CO2 Extract. CAS No. MIXTURE. Kosher: Y. VIGON Item # 504850. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils.
America & Internationally
Rooibos Milled Powder (Aspalathus Linearis)
Rooibos Milled Powder (Aspalathus Linearis).
CA, FL & NJ
Ropeginterferon alfa-2b
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b. CAS No. 1335098-50-4. Pack Sizes: 50 μg; 250 μg. Product ID: HY-P99348.
Ropidoxuridine
Ropidoxuridine is a novel, orally available 5-substituted 2-pyrimidinone-2'-deoxyribonucleoside analogue and prodrug of 5-iododeoxyuridine (IUdR). It has radiosensitizing activity. It is efficiently converted to idoxuridine (IUdR) by a hepatic aldehyde oxidase. It is incorporated into DNA during replication, thereby sensitizing cells to ionizing radiation by increasing DNA strand breaks. It is associated with a lower toxicity profile and improved anti-tumor activity. It has dose responsive and synergistic effects. It has also shown reduced toxicity, with better tissue incorporation and improved anti-tumor activity. It maybe used to treat colorectal, gastric, and pancreatic cancer, and other solid tumors. Uses: Ropidoxuridine has radiosensitizing activity. it maybe used to treat colorectal, gastric, and pancreatic cancer, and other solid tumors. Alternative Names: IPdR; D08992; Ropidoxuridine; 5-Iodo-2-pyrimidinone-2-deoxyribose; 1-(2-deoxy-beta-ribofuranosyl)-5-iodo-2-pyrimidinone; 5-Iodo-2-pyrimidinone-2'-deoxyribose. Grades: >98 %. CAS No. 93265-81-7. Molecular formula: C9H11IN2O4. Mole weight: 338.10.
Ropinirole Aminoacetic Acid
Ropinirole impurity. It was found that these compounds were all poor competitive inhibitors of GABA-AT, but some were substrates of the enzyme, suggesting their utility as scaffolds for potential GABA-AT mechanism-based inactivators. Group: Biochemicals. Alternative Names: 2-Amino-6-[2- (dipropylamino) ethyl]benzeneacetic Acid. Grades: Highly Purified. CAS No. 920755-10-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ropinirole-d4 Hydrochloride
Labelled Ropinirole, an antiparkinsonian agent. A selective dopamine D2-receptor agonist. Group: Biochemicals. Alternative Names: 4-[2-(Dipropylamino-d4)ethyl]-1,3-dihydro-2H-indol-2-one Hydrochloride; 4-[2-(Di-n-propylamino-d4)ethyl]-2(3H)-indolone Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ropinirole EP Impurity B (Hydrochloride)
Ropinirole EP Impurity B (Hydrochloride). Uses: For analytical and research use. Alternative Names: 4-(2-((2-methylpentyl)amino)ethyl)indolin-2-one hydrochloride. CAS No. 221264-33-1. Molecular formula: C16H24N2O·HCl. Mole weight: 296.84. Catalog: APB221264331.
Ropinirole EP Impurity C
Ropinirole EP Impurity C. Uses: For analytical and research use. Alternative Names: (Z)-4-(2-(dipropylamino)ethyl)-3-propylideneindolin-2-one. CAS No. 784110-47-0. Molecular formula: C19H28N2O. Mole weight: 300.22. Catalog: APB784110470.
Ropinirole EP Impurity D
Ropinirole EP Impurity D. Uses: For analytical and research use. Alternative Names: N-Despropyl Ropinirole; 4-(2-(propylamino)ethyl)indolin-2-one. CAS No. 106916-16-9. Molecular formula: C13H18N2O. Mole weight: 218.14. Catalog: APB106916169.
Ropinirole EP Impurity F
Ropinirole EP Impurity F. Uses: For analytical and research use. Alternative Names: 4-(2-hydroxyethyl)indolin-2-one. CAS No. 139122-19-3. Molecular formula: C10H11NO2. Mole weight: 177.20. Catalog: APB139122193.
Ropinirole EP Impurity G
Ropinirole EP Impurity G. Uses: For analytical and research use. Alternative Names: N-(2-(1H-indol-4-yl)ethyl)-N-propylpropan-1-amine. CAS No. 76149-15-0. Molecular formula: C16H24N2. Mole weight: 244.19. Catalog: APB76149150.
Ropinirole hydrochloride
25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H25ClN2O. CAS No. 91374-20-8. Prepack ID 56483601-25mg. Molecular Weight 296.84. See USA prepack pricing.
Ropinirole hydrochloride
Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF 101468 hydrochloride. CAS No. 91374-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-B0623A.
Ropinirole Hydrochloride
Ropinirole Hydrochloride is a non-ergot dopamine D2/D3 receptor agonist used for the treatment of Parkinson's disease and Restless Legs Syndrome (RLS). Its chemical structure is distinct from ergot derivatives such as bromocriptine and cabergoline, eliminating the risk of ergot-related cardiac valvulopathy. It demonstrates preferential binding to D3 receptors, which are highly expressed in the mesolimbic and nigrostriatal dopaminergic pathways. Applications: Ropinirole hydrochloride is indicated as monotherapy for early-stage parkinson's disease and as adjunctive therapy to levodopa in advanced disease. it is also indicated for the treatment of moderate to severe restless legs syndrome. Category: Active pharmaceutical ingredients. Synonyms: 4-[2-(Di-n-propylamino)ethyl]-2(3H)-indolone Hydrochloride;4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one Hydrochloride. CAS No. 91374-20-8. Product ID: API91374208. Molecular formula: C16H25ClN2O. Mole weight: 296.83. EINECS: 635-615-9. InChIKey: XDXHAEQXIBQUEZ-UHFFFAOYSA-N. Appearance: Pale yellow powder.
Ropinirole, Hydrochloride
An antiparkinsonian agent. A selective dopamine D2-receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 91374-20-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences.
Worldwide
Ropinirole Impurity 1
Ropinirole Impurity 1. Uses: For analytical and research use. CAS No. 120427-93-2. Molecular formula: C10H9NO. Mole weight: 159.19. Catalog: APB120427932.
Ropinirole Impurity 10
Ropinirole Impurity 10. Uses: For analytical and research use. Alternative Names: 4-(2-chloroethyl)indolin-2-one. CAS No. 168476-59-3. Molecular formula: C10H10ClNO. Mole weight: 195.65. Catalog: APB168476593.
Ropinirole Impurity 2
Ropinirole Impurity 2. Uses: For analytical and research use. CAS No. 91374-25-3. Molecular formula: C16H25ClN2O4. Mole weight: 344.84. Catalog: APB91374253.
Ropinirole Impurity 3
Ropinirole Impurity 3. Uses: For analytical and research use. CAS No. 2724840-11-1. Molecular formula: C33H48N4O2. Mole weight: 532.77. Catalog: APB2724840111.
Ropinirole Impurity 4
Ropinirole Impurity 4. Uses: For analytical and research use. CAS No. 1027600-42-5. Molecular formula: C17H26N2O2. Mole weight: 290.41. Catalog: APB1027600425.
Ropinirole Impurity 5
Ropinirole Impurity 5. Uses: For analytical and research use. Molecular formula: C33H48N4O2. Mole weight: 532.77. Catalog: APB12168.
Ropinirole Impurity 6
Ropinirole Impurity 6. Uses: For analytical and research use. Molecular formula: C33H50Cl2N4O2. Mole weight: 605.69. Catalog: APB12169.
Ropinirole Impurity 7
Ropinirole Impurity 7. Uses: For analytical and research use. CAS No. 1800102-50-4. Molecular formula: C33H48N4O2. Mole weight: 532.77. Catalog: APB1800102504.
Ropinirole N-oxide
Ropinirole N-oxide. Alternative Names: 1,3-Dihydro-4-[2-(oxidodipropylamino)ethyl]-2H-indol-2-one. CAS No. 1076199-41-1. Product ID: ACM1076199411. Molecular formula: C16H24N2O2. Mole weight: 276.37. Alfa Chemistry - ISO 9001:32057 Certified.
Ropinirole N-Oxide
A metabolite of ropinirole. This compound has been found to decompose readily in DMSO and Chloroform. Group: Biochemicals. Alternative Names: 1, 3-Dihydro-4-[2- (oxidodipropylamino) ethyl]-2H-indol-2-one. Grades: Highly Purified. CAS No. 1076199-41-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ropivacaine
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[1][2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane[3]. Ropivacaine is used for the research of neuropathic pain management[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 84057-95-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0563.
Ropivacaine-d7 Hydrochloride
Labeled Ropivacaine. Anesthetic (local). Group: Biochemicals. Grades: Highly Purified. CAS No. 1217667-10-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ropivacaine EP Impurity C
Ropivacaine EP Impurity C. Uses: For analytical and research use. CAS No. 24358-84-7. Molecular formula: C15H22N2O. Mole weight: 246.35. Catalog: APB24358847.
Ropivacaine EP Impurity D HCl
Ropivacaine EP Impurity D HCl. Uses: For analytical and research use. CAS No. 112773-86-1. Molecular formula: C16H25ClN2O. Mole weight: 296.84. Catalog: APB112773861.
Ropivacaine EP Impurity E
Ropivacaine EP Impurity E. Uses: For analytical and research use. CAS No. 265120-58-9. Molecular formula: C17H26N2O. Mole weight: 274.41. Catalog: APB265120589.
Ropivacaine EP Impurity F
Ropivacaine EP Impurity F. Uses: For analytical and research use. CAS No. 1945965-95-6. Molecular formula: C17H24N2O. Mole weight: 272.39. Catalog: APB1945965956.
Ropivacaine hydrochloride
25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H26N2O · HCl · H2O. CAS No. 98717-15-8. Prepack ID 90028387-25g. Molecular Weight 310.06. See USA prepack pricing.
Ropivacaine hydrochloride
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H26N2O · HCl · H2O. CAS No. 98717-15-8. Prepack ID 90028387-5g. Molecular Weight 310.06. See USA prepack pricing.
Ropivacaine Hydrochloride
Ropivacaine hydrochloride is the hydrochloride salt of ropivacaine, a long-acting amide-type local anesthetic approved by the FDA in 1996 for surgical anesthesia and acute pain management. It is chemically related to bupivacaine but is formulated as the pure S-enantiomer to enhance its safety profile. Applications: Ropivacaine hydrochloride is indicated for epidural blocks including cesarean section, major nerve blocks, local infiltration, and continuous epidural infusion for postoperative or labor pain management. lower concentrations (0.2%) provide analgesia with minimal motor block, while higher concentrations (0.5-1%) produce complete surgical anesthesia with motor blockade. compared to bupivacaine, ropivacaine offers faster regression of sensory and motor blockade, potentially facilitating earlier mobilization, and is associated with reduced incidence of hypotension and cardiotoxicity. Category: Anesthetic analgesia apis. Synonyms: ROPIVACAINE HCl, Ropivacaine monohydrochloride, DTXSID2048379. CAS No. 98717-15-8. Product ID: API0232524. Molecular formula: C17H27ClN2O. Mole weight: 310.86. EINECS: 663-286-1. InChIKey: NDNSIBYYUOEUSV-RSAXXLAASA-N.
Ropivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. The name ropivacaine refers to both the racemate and the marketed S-enantiomer. Ropivacaine hydrochloride is commonly marketed by AstraZeneca under the trade name Naropin. Ropivacaine was developed after bupivacaine was noted to be associated with cardiac arrest, particularly in pregnant women. Ropivacaine was found to have less cardiotoxicity than bupivacaine in animal models. Group: Biochemicals. Alternative Names: (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide Hydrochloride Hydrate; LEA-103. Grades: Highly Purified. CAS No. 132112-35-7. Pack Sizes: 100mg, 250mg, 500mg, 1g, 10g. Molecular Formula: C??H??ClN?O? , Molecular Weight: 328.88. US Biological Life Sciences.
Worldwide
Ropivacaine Impurity 10
Ropivacaine Impurity 10. Uses: For analytical and research use. CAS No. 439591-67-0. Molecular formula: C14H14N2O. Mole weight: 226.28. Catalog: APB439591670.