A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Robinin | Robinin. Group: Biochemicals. CAS No. 301-19-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Robinin | Robinin is a flavonoid that can be extracted from the leaves of purple cowpea, inhibiting TGF-β, TLR4/NF-κB and TLR2-PI3k-AKT signaling pathways. Robinin exerts anti-inflammatory and anti-tumor effects. The combination of Robinin and Methotrexate (HY-14519) reduces inflammation in experimental arthritis, Robinin can decrease the Doxorubicin (HY-15142A) induced cardiac toxicity effect[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 301-19-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-N1346. |  |
| Roblitinib | Roblitinib (FGF-401) is an orally active and highly selective FGFR4 inhibitor with an IC50 of 1.9 nM[1]. Roblitinib has antitumor activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FGF-401. CAS No. 1708971-55-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101568. | |
| Robotnikinin (N-2-acetamide) | Sonic hedgehog (Shh) signaling small molecule modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein. Group: Biochemicals. Alternative Names: N--2-acetamide. Grades: Highly Purified. CAS No. 1132653-79-2. Pack Sizes: 1mg. Molecular Formula: C25H27ClN2O4. US Biological Life Sciences. | Worldwide |
| Roburic acid | Roburic acid acts as an anti-inflammatory, anti-tumor and osteoclastogenesis inhibitor, with a Ki of 7.066 μM against human TNF, an IC50 of 9 μM against human COX-2, and an IC50 of 5 μM against ovine COX-1. Roburic acid reduces the production of inflammatory mediators such as NO and IL-6 in macrophages by inhibiting the NF-κB and MAPK (p38/JNK) pathways. By competitively inhibiting the TNF-TNF-R1 interaction, Roburic acid blocks the downstream NF-κB signaling pathway, thereby inducing cell cycle arrest and apoptosis in cancer cells. Roburic acid specifically inhibits osteoclastogenesis and bone resorption by suppressing the RANKL/TRAF6/NF-κB/NFATc1 axis. Roburic acid can be used in research related to osteolytic diseases such as osteoporosis, colorectal cancer and inflammatory diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6812-81-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-N0481. | |
| Roburic Acid | Roburic Acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 6812-81-3. Pack Sizes: 20mg. Molecular Formula: C30H48O2, Molecular Weight: 440.7. US Biological Life Sciences. | Worldwide |
| Robustol methyl ether | Robustol methyl ether. CAS No. 27825-39-4. Molecular formula: C29H42O4. Mole weight: 454.64. |  |
| Rocaglamide | Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Roc-A. CAS No. 84573-16-0. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19356. | |
| ROCAGLAMIDE | Rocaglamide is the first cyclopenta[b]benzofuran derivative extracted from Aglaia elliptifolia in 1982 by King and colleagues. Its IC50 value is ~50 nM for the heat shock reporter. It has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. It is an immunosuppressant that inhibits activation of NF-kB and NF-AT. It markedly inhibited tumor growth from Huh-7 cells propagated in severe combined immunodeficient mice. It induces apoptosis in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells. It inhibit protein synthesis without affecting DNA or RNA synthesis. Uses: Rocaglamide has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. it is an immunosuppressant that inhibits activation of nf-kb and nf-at. it inhibit protein synthesis without affecting dna or rna synthesis. Synonyms: Rocaglamide; Rocaglamide A; RocA; NSC 326408. (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide; NSC 326408; Roc-A; Rocaglamide A; 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-; [1R-(1α. Grade: 95%. CAS No. 84573-16-0. Molecular formula: C29H3 | |
| Rocagloic acid | Rocagloic acid is a racaglamide derivative isolated from the fruits of Aglaia elliptifolia with potent cytotoxicity[1]. Uses: Scientific research. Category: Natural products. CAS No. 190385-15-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19355. | |
| Rocatinlimab | Rocatinlimab (AMG 451) (KHK4083) is a fully human immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG 451; KHK4083. CAS No. 2431972-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99955. | |
| Roccellaric acid | Roccellaric acid. Synonyms: 3-Furancarboxylic acid, tetrahydro-4-methyl-5-oxo-2-tridecyl-, [2R-(2α,3β,4α)]-; (2R,3S,4S)-Tetrahydro-4-methyl-5-oxo-2-tridecyl-3-furancarboxylic acid; (+)-Roccellaric acid; Dihydroneoprotolichesteric acid; Nephromopsinic acid (-). CAS No. 19464-85-8. Molecular formula: C19H34O4. Mole weight: 326.47. | |
| Rociletinib | Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CO-1686; AVL-301; CNX-419. CAS No. 1374640-70-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15729. | |
| ROCK2-IN-6 hydrochloride | ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762238-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156592A. | |
| ROCK inhibitor-2 | ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM. ROCK inhibitor-2 exhibits antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1127308-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119937. | |
| Rock inhibitor y-27632 | Rock inhibitor y-27632. Alternative Names: 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide. CAS No. 146986-50-7. Purity: 98%+. Product ID: ACM146986507. Molecular formula: C14H21N3O·2HCl. Mole weight: 320.26. IUPAC Name: 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide. Canonical SMILES: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Rock Phosphate Coarse Powder | Rock Phosphate Coarse Powder - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Rocuronium Bis-quaternary Ammonium Bromide Impurity | Rocuronium Bis-quaternary Ammonium Bromide Impurity. Uses: For analytical and research use. Alternative Names: 4-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-16-(1-allylpyrrolidin-1-ium-1-yl)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-2-yl)-4-allylmorpholin-4-ium bromide. Molecular formula: C35H58Br2N2O4. Mole weight: 730.65. Catalog: APB01766. |  |
| Rocuronium bromide | Rocuronium bromide. CAS No. 119302-91-9. Product ID: ACM119302919. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Rocuronium bromide | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C32H53BrN2O4. CAS No. 119302-91-9. Prepack ID 90026899-1g. Molecular Weight 609.68. See USA prepack pricing. |  |
| Rocuronium Bromide | Aminosteroid, competitive neuromuscular blocker. Group: Biochemicals. Alternative Names: 1-[(2 β, 3α, 5α, 16 β,17 β)-17-(Acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)pyrrolidinium Bromide; Org-9426; Esmeron; Zemuron. Grades: Highly Purified. CAS No. 119302-91-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Rocuronium Bromide | Rocuronium Bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORG 9426 Bromide. CAS No. 119302-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17440. | |
| Rocuronium Bromide EP Impurity A | Rocuronium Bromide EP Impurity A. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-hydroxy-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate. CAS No. 119302-24-8. Molecular formula: C29H48N2O4. Mole weight: 488.70. Catalog: APB119302248. | |
| Rocuronium Bromide EP Impurity B | Rocuronium Bromide EP Impurity B. Uses: For analytical and research use. Alternative Names: 1-allyl-1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-diacetoxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)pyrrolidin-1-ium bromide. CAS No. 122483-73-2. Molecular formula: C34H55BrN2O5. Mole weight: 651.71. Catalog: APB122483732. | |
| Rocuronium Bromide EP Impurity C | Rocuronium Bromide EP Impurity C. Uses: For analytical and research use. Alternative Names: 1-allyl-1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-dihydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)pyrrolidin-1-ium bromide. CAS No. 119302-86-2. Molecular formula: C30H51BrN2O3. Mole weight: 567.64. Catalog: APB119302862. | |
| Rocuronium Bromide EP Impurity D | Rocuronium Bromide EP Impurity D. Uses: For analytical and research use. Alternative Names: 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetoxy-17-hydroxy-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. CAS No. 1190105-63-5. Molecular formula: C32H53BrN2O4. Mole weight: 609.68. Catalog: APB1190105635. | |
| Rocuronium Bromide EP Impurity E | Rocuronium Bromide EP Impurity E. Uses: For analytical and research use. Alternative Names: 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-2-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. CAS No. 1190105-65-7. Molecular formula: C32H53N2O3·Br. Mole weight: 593.68. Catalog: APB1190105657. | |
| Rocuronium Bromide EP Impurity F | Rocuronium Bromide EP Impurity F. Uses: For analytical and research use. Alternative Names: 1-allyl-1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-diacetoxy-10,13-dimethyl-2-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)pyrrolidin-1-ium bromide. CAS No. 1190105-66-8. Molecular formula: C34H55BrN2O4. Mole weight: 635.72. Catalog: APB1190105668. | |
| Rocuronium Bromide EP Impurity G | Rocuronium Bromide EP Impurity G. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. CAS No. 119302-20-4. Molecular formula: C27H46N2O3. Mole weight: 446.67. Catalog: APB119302204. | |
| Rocuronium Bromide EP Impurity H Bromide | Rocuronium Bromide EP Impurity H Bromide. Uses: For analytical and research use. CAS No. 1190105-67-9. Molecular formula: C32H49BrN2O4. Mole weight: 605.66. Catalog: APB1190105679. | |
| Rocuronium Bromide Impurity 11 | Rocuronium Bromide Impurity 11. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-3-hydroxy-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one. Molecular formula: C19H30O2. Mole weight: 290.44. Catalog: APB01767. | |
| Rocuronium Bromide Impurity 13 | Rocuronium Bromide Impurity 13. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(4H)-one. CAS No. 14639-79-3. Molecular formula: C19H28O. Mole weight: 272.43. Catalog: APB14639793. | |
| Rocuronium Bromide Impurity 14 | Rocuronium Bromide Impurity 14. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-5,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one. CAS No. 14935-81-0. Molecular formula: C19H28O. Mole weight: 272.43. Catalog: APB14935810. | |
| Rocuronium Bromide Impurity 15 | Rocuronium Bromide Impurity 15. Uses: For analytical and research use. Alternative Names: (5S,8R,9S,10S,13S,14S)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate. CAS No. 50588-22-2. Molecular formula: C21H30O2. Mole weight: 314.46. Catalog: APB50588222. | |
| Rocuronium Bromide Impurity 26 | Rocuronium Bromide Impurity 26. Uses: For analytical and research use. Alternative Names: (1R,2S,5aS,6aS,7aR,8aS,10aS)-8a,10a-dimethyl-2-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[7,8]phenanthro[2,3-b]oxiren-1-ol. Molecular formula: C23H37NO2. Mole weight: 359.55. Catalog: APB01765. | |
| Rocuronium Bromide Impurity 27 | Rocuronium Bromide Impurity 27. Uses: For analytical and research use. Alternative Names: 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-3-(allyloxy)-10,13-dimethyl-2-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. Molecular formula: C35H57BrN2O4. Mole weight: 649.74. Catalog: APB01764. | |
| Rocuronium Bromide Impurity 32 | Rocuronium Bromide Impurity 32. Uses: For analytical and research use. Alternative Names: (3R,4R,5R,8R,9S,10R,13S,14S,16S,17R)-10,13-dimethyl-4-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C27H46N2O3. Mole weight: 446.67. Catalog: APB01763. | |
| Rocuronium Bromide Impurity 34 | Rocuronium Bromide Impurity 34. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2,16-di(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. CAS No. 144209-33-6. Molecular formula: C27H46N2O2. Mole weight: 430.67. Catalog: APB144209336. | |
| Rocuronium Bromide Impurity 35 | Rocuronium Bromide Impurity 35. Uses: For analytical and research use. Alternative Names: (2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-hydroxy-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate. Molecular formula: C29H48N2O4. Mole weight: 488.70. Catalog: APB02186. | |
| Rocuronium Bromide Impurity 38 | Rocuronium Bromide Impurity 38. Uses: For analytical and research use. Alternative Names: (2R,3R,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-dimethyl-2-morpholino-16-(pyrrolidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol. Molecular formula: C27H46N2O3. Mole weight: 446.67. Catalog: APB02111. | |
| Rocuronium Bromide Isomer Impurity | Rocuronium Bromide Isomer Impurity. Uses: For analytical and research use. Alternative Names: Rocuronium Bromide Impurity 33; 1-((3R,4R,5R,8R,9S,10R,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-4-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. Molecular formula: C32H53N2O4·Br. Mole weight: 609.67. Catalog: APB01762. | |
| Rocuronium Impurity11 | Rocuronium Impurity11. Uses: For analytical and research use. Molecular formula: C35H57BrN2O4. Mole weight: 649.76. Catalog: APB09617. | |
| Rocuronium Impurity12 | Rocuronium Impurity12. Uses: For analytical and research use. Molecular formula: C32H53BrN2O4. Mole weight: 609.69. Catalog: APB09618. | |
| Rodaplutin | Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Synonyms: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6. | |
| R-(-)-O-Desmethyl venlafaxine | R-(-)-O-Desmethyl venlafaxine. Group: Biochemicals. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. Grades: Highly Purified. CAS No. 142761-11-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H25NO2. US Biological Life Sciences. | Worldwide |
| R-(-)-O-Desmethyl Venlafaxine-[d6] | R-(-)-O-Desmethyl-Venlafaxine-[d6] is the labelled analogue of R-(-)-O-Desmethyl-Venlafaxine, a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: (R)-4-(2-(bis(methyl-d3)amino)-1-(1-hydroxycyclohexyl)ethyl)pheno. Grade: 98%. CAS No. 1062609-96-4. Molecular formula: C16H19D6NO2. Mole weight: 269.37. | |
| Roemerine | Roemerine is found in the leaves of Nelumbo nucifera, which has some anti-prostate cancer effect and alleviates adverse reactions in paclitaxel combination administration. Synonyms: Remerine; Aporheine. Grade: > 95%. CAS No. 548-08-3. Molecular formula: C18H17NO2. Mole weight: 279.33. | |
| Rofapitide tetraxetan | Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-147057. | |
| Rofecoxib | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-100mg. Molecular Weight 314.36. See USA prepack pricing. | |
| Rofecoxib | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-1g. Molecular Weight 314.36. See USA prepack pricing. | |
| Rofecoxib | Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-17372. | |
| Roflumilast | Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDE4A4, PDE4B1, and PDE4B2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15455. | |
| Roflumilast | Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy. Synonyms: BY217; BY-217; BY 217; B 9302-107; B9302-107; B-9302-107; BYK 20869; BYK-20869; BYK20869; Daxas; Daliresp. Grade: 99%. CAS No. 162401-32-3. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.207. | |
| Roflumilast | Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Category: Active pharmaceutical ingredients. CAS No. 162401-32-3. Product ID: API162401323. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.21. |  |
| Roflumilast | Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences. | Worldwide |
| Roflumilast-[d3] | A deuterated Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Daxas-d3; 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. Grade: > 95%. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. | |
| Roflumilast-d4 | Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast-[d4] | One of the isotopic labelled form of Roflumilast, which is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4; Daxas-d4. Grade: >98%. CAS No. 1398065-69-4. Molecular formula: C17H10D4Cl2F2N2O3. Mole weight: 407.23. | |
| Roflumilast Impurity 1 | Roflumilast Impurity 1. Uses: For analytical and research use. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. Catalog: APB292135785. | |
| Roflumilast Impurity 2 | Roflumilast Impurity 2. Uses: For analytical and research use. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.41. Catalog: APB1352122372. | |
| Roflumilast Impurity 3 | Roflumilast Impurity 3. Uses: For analytical and research use. CAS No. 1391053-75-0. Molecular formula: C17H15ClF2N2O3. Mole weight: 368.76. Catalog: APB1391053750. | |
| Roflumilast Impurity 4 | Roflumilast Impurity 4. Uses: For analytical and research use. Molecular formula: C16H10F2O8. Mole weight: 368.24. Catalog: APB12076. | |
| Roflumilast Impurity E | Roflumilast Impurity E is an impurity of Roflumilast, which acts as a selective and long-acting enzyme PDE-4 inhibitor (IC50 value of 0.8 nM). Category: Active pharmaceutical ingredients. CAS No. 1391052-76-8. Product ID: API1391052768. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. | |
| Roflumilast N-oxide | Roflumilast N-oxide is a PDE type 4 inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 292135-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100639. | |
| Roflumilast N-oxide | Roflumilast N-oxide is an inhibitor of PDE type 4. Category: Active pharmaceutical ingredients. CAS No. 292135-78-5. Product ID: API292135785. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast N-Oxide | Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast N-oxide-[d4] | A deuterated impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Roflumilast-d4 N-Oxide; 3-(Cyclopropylmethoxy-d4)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-(cyclopropyl-d4) methoxybenzamide. Grade: > 95%. CAS No. 1794760-31-8. Molecular formula: C17H10Cl2F2N2O4D4. Mole weight: 423.24. | |
| Roflumilast Related Compound C | A metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast. Synonyms: 4-Amino-3,5-dichloropyridine; 4-Pyridinamine, 3,5-dichloro-; 3,5-Dichloro-4-pyridinamine; Pyridine, 4-amino-3,5-dichloro-; 3,5-Dichloro-4-aminopyridine; 3,5-Dichloropyridin-4-ylamine; 3,5-Dichloropyridine-4-amine. Grade: ≥95%. CAS No. 22889-78-7. Molecular formula: C5H4Cl2N2. Mole weight: 163.01. | |
| Roflumilast Related Compound D | An impurity and intermediate in the preparation of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid; Benzoic acid, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-. Grade: 98%. CAS No. 162401-62-9. Molecular formula: C12H12F2O4. Mole weight: 258.22. | |
| Roflupram | Roflupram is a selective, orally active and brain-penetrant PDE4 inhibitor, with an IC50 of 26.2 nM for core catalytic domains of human PDE4. Roflupram can reverse cognitive deficits and reduce the production of pro-inflammatory factors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093412-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115383. | |
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