American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
Rocuronium Bromide Isomer Impurity Rocuronium Bromide Isomer Impurity. Uses: For analytical and research use. Alternative Names: Rocuronium Bromide Impurity 33; 1-((3R,4R,5R,8R,9S,10R,13S,14S,16S,17R)-17-acetoxy-3-hydroxy-10,13-dimethyl-4-morpholinohexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-allylpyrrolidin-1-ium bromide. Molecular formula: C32H53N2O4·Br. Mole weight: 609.67. Catalog: APB01762. Alfa Chemistry Analytical Products
Rocuronium Impurity11 Rocuronium Impurity11. Uses: For analytical and research use. Molecular formula: C35H57BrN2O4. Mole weight: 649.76. Catalog: APB09617. Alfa Chemistry Analytical Products 2
Rocuronium Impurity12 Rocuronium Impurity12. Uses: For analytical and research use. Molecular formula: C32H53BrN2O4. Mole weight: 609.69. Catalog: APB09618. Alfa Chemistry Analytical Products 2
Rodaplutin Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Synonyms: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6. BOC Sciences 12
R-(-)-O-Desmethyl venlafaxine R-(-)-O-Desmethyl venlafaxine. Group: Biochemicals. Alternative Names: (R)-(-)-4-[2-(Dimethylamino)-1-(1-hydroxycyclo-hexyl)ethyl]phenol; (-)-O-Desmethylvenlafaxine; (R)-(-)-O-Desmethylvenlafaxine. Grades: Highly Purified. CAS No. 142761-11-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H25NO2. US Biological Life Sciences. USBiological 13
Worldwide
R-(-)-O-Desmethyl Venlafaxine-[d6] R-(-)-O-Desmethyl-Venlafaxine-[d6] is the labelled analogue of R-(-)-O-Desmethyl-Venlafaxine, a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: (R)-4-(2-(bis(methyl-d3)amino)-1-(1-hydroxycyclohexyl)ethyl)pheno. Grade: 98%. CAS No. 1062609-96-4. Molecular formula: C16H19D6NO2. Mole weight: 269.37. BOC Sciences 2
Roemerine Roemerine is found in the leaves of Nelumbo nucifera, which has some anti-prostate cancer effect and alleviates adverse reactions in paclitaxel combination administration. Synonyms: Remerine; Aporheine. Grade: > 95%. CAS No. 548-08-3. Molecular formula: C18H17NO2. Mole weight: 279.33. BOC Sciences 9
Rofapitide tetraxetan Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-147057. MedChemExpress MCE
Rofecoxib 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-100mg. Molecular Weight 314.36. See USA prepack pricing. Molekula Americas
Rofecoxib Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC50s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-17372. MedChemExpress MCE
Rofecoxib 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H14O4S. CAS No. 162011-90-7. Prepack ID 85601753-1g. Molecular Weight 314.36. See USA prepack pricing. Molekula Americas
Roflumilast Roflumilast has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). While Roflumilast was found to be effective in clinical trials, it produced several dose-limiting side effects including nausea, diarrhoea and headache, and development is continuing in an attempt to minimise the incidence of side effects while retaining clinical efficacy. Synonyms: BY217; BY-217; BY 217; B 9302-107; B9302-107; B-9302-107; BYK 20869; BYK-20869; BYK20869; Daxas; Daliresp. Grade: 99%. CAS No. 162401-32-3. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.207. BOC Sciences 2
Roflumilast Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Category: Active pharmaceutical ingredients. CAS No. 162401-32-3. Product ID: API162401323. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.21. Protheragen
Roflumilast Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences. USBiological 13
Worldwide
Roflumilast Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDE4A4, PDE4B1, and PDE4B2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15455. MedChemExpress MCE
Roflumilast-[d3] A deuterated Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Daxas-d3; 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. Grade: > 95%. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. BOC Sciences 2
Roflumilast-d4 Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 13
Worldwide
Roflumilast-[d4] One of the isotopic labelled form of Roflumilast, which is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-(Cyclopropyl-d4)methoxy-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4; Daxas-d4. Grade: >98%. CAS No. 1398065-69-4. Molecular formula: C17H10D4Cl2F2N2O3. Mole weight: 407.23. BOC Sciences 2
Roflumilast Impurity 1 Roflumilast Impurity 1. Uses: For analytical and research use. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. Catalog: APB292135785. Alfa Chemistry Analytical Products 3
Roflumilast Impurity 2 Roflumilast Impurity 2. Uses: For analytical and research use. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.41. Catalog: APB1352122372. Alfa Chemistry Analytical Products 3
Roflumilast Impurity 3 Roflumilast Impurity 3. Uses: For analytical and research use. CAS No. 1391053-75-0. Molecular formula: C17H15ClF2N2O3. Mole weight: 368.76. Catalog: APB1391053750. Alfa Chemistry Analytical Products 3
Roflumilast Impurity 4 Roflumilast Impurity 4. Uses: For analytical and research use. Molecular formula: C16H10F2O8. Mole weight: 368.24. Catalog: APB12076. Alfa Chemistry Analytical Products 2
Roflumilast Impurity E Roflumilast Impurity E is an impurity of Roflumilast, which acts as a selective and long-acting enzyme PDE-4 inhibitor (IC50 value of 0.8 nM). Category: Active pharmaceutical ingredients. CAS No. 1391052-76-8. Product ID: API1391052768. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. Protheragen
Roflumilast N-oxide Roflumilast N-oxide is an inhibitor of PDE type 4. Category: Active pharmaceutical ingredients. CAS No. 292135-78-5. Product ID: API292135785. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. Protheragen
Roflumilast N-oxide Roflumilast N-oxide is a PDE type 4 inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 292135-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100639. MedChemExpress MCE
Roflumilast N-Oxide Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 13
Worldwide
Roflumilast N-oxide-[d4] A deuterated impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Roflumilast-d4 N-Oxide; 3-(Cyclopropylmethoxy-d4)-N-(3,5-dichloro-1-oxido-4-pyridinyl)-4-(difluoromethoxy)benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-(cyclopropyl-d4) methoxybenzamide. Grade: > 95%. CAS No. 1794760-31-8. Molecular formula: C17H10Cl2F2N2O4D4. Mole weight: 423.24. BOC Sciences 2
Roflumilast Related Compound C A metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast. Synonyms: 4-Amino-3,5-dichloropyridine; 4-Pyridinamine, 3,5-dichloro-; 3,5-Dichloro-4-pyridinamine; Pyridine, 4-amino-3,5-dichloro-; 3,5-Dichloro-4-aminopyridine; 3,5-Dichloropyridin-4-ylamine; 3,5-Dichloropyridine-4-amine. Grade: ≥95%. CAS No. 22889-78-7. Molecular formula: C5H4Cl2N2. Mole weight: 163.01. BOC Sciences 2
Roflumilast Related Compound D An impurity and intermediate in the preparation of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-Cyclopropylmethoxy-4-difluoromethoxybenzoic acid; Benzoic acid, 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-. Grade: 98%. CAS No. 162401-62-9. Molecular formula: C12H12F2O4. Mole weight: 258.22. BOC Sciences 2
Roflupram Roflupram is a selective, orally active and brain-penetrant PDE4 inhibitor, with an IC50 of 26.2 nM for core catalytic domains of human PDE4. Roflupram can reverse cognitive deficits and reduce the production of pro-inflammatory factors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093412-18-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115383. MedChemExpress MCE
Roflurane Roflurane is a halocarbon drug. It has been investigated as an inhalational anesthetic. Category: Active pharmaceutical ingredients. Synonyms: DA-893. CAS No. 679-90-3. Product ID: API679903. Molecular formula: C3H4BrF3O. Mole weight: 192.96. Protheragen
Roginolisib Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827. MedChemExpress MCE
Rogocekib Rogocekib is an orally effective CLK 2 inhibitor, with an IC50 of 1.4 nM, showing anti-tumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CTX-712. CAS No. 2144751-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144875. MedChemExpress MCE
Rohinitib Rohinitib is a potent and specific eIF4A inhibitor. Rohinitib induces cell apoptosis of acute myeloid leukemia (AML) cell lines and reduces the leukemia burden of AML xenograft model. Rohinitib can be used for the research of AML[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1139253-73-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148422. MedChemExpress MCE
Rolapitant Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 552292-08-7. Product ID: API552292087. Molecular formula: C25H26F6N2O2. Mole weight: 500.48. Protheragen
Rolapitant Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751. MedChemExpress MCE
Rolapitant hydrochloride Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting, and orally active neurokinin 1 (NK1) receptor antagonist with a K_i of 0.66 nM, which does not interact with CYP3A4 and demonstrates potent centrally-mediated anti-emetic activity in both acute and delayed ferret emesis models. Category: Active pharmaceutical ingredients. CAS No. 858102-79-1. Product ID: API858102791. Molecular formula: C25H27ClF6N2O2. Mole weight: 536.94. Protheragen
Rolapitant hydrochloride hydrate Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). Category: Active pharmaceutical ingredients. CAS No. 914462-92-3. Product ID: API914462923. Molecular formula: C25H29ClF6N2O3. Mole weight: 554.95. Protheragen
Rolapitant Impurity 1 Rolapitant Impurity 1. Uses: For analytical and research use. Molecular formula: C25H22D4F6N2O2. Mole weight: 504.51. Catalog: APB11169. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 2 Rolapitant Impurity 2. Uses: For analytical and research use. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741260. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 3 Rolapitant Impurity 3. Uses: For analytical and research use. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741259. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 4 Rolapitant Impurity 4. Uses: For analytical and research use. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB552292736. Alfa Chemistry Analytical Products 4
Rolapitant Impurity 5 Rolapitant Impurity 5. Uses: For analytical and research use. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741306. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 6 Rolapitant Impurity 6. Uses: For analytical and research use. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741282. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 7 Rolapitant Impurity 7. Uses: For analytical and research use. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741293. Alfa Chemistry Analytical Products 2
Rolapitant Impurity 8 Rolapitant Impurity 8. Uses: For analytical and research use. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49. Catalog: APB1214741271. Alfa Chemistry Analytical Products 2
Roledumab Roledumab (LFB-R593) is a human IgG1-κ antibody targeting RHD/CD240D. Roledumab is expressed by YB2/0 rat hybridoma cells[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: LFB-R593. CAS No. 1174008-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99880. MedChemExpress MCE
Rolipram Rolipram. Group: Biochemicals. Grades: Purified. CAS No. 61413-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
Rolipram Rolipram is a PDE4 inhibitor, with blood-brain barrier permeability, that reverses β-amyloid-induced learning and memory impairment in rats. Rolipram elevates intracellular cAMP and clevels and regulates the cAMP/CREB signaling pathway, thereby alleviating neuroinflammation and apoptotic responses. Rolipram promotes neuronal differentiation of human bone marrow mesenchymal stem cells and inhibits Methamphetamine- and morphine-induced hyperlocomotion in mice. Rolipram also reduces the viability of glioblastoma stem-like cells and enhances Bevacizumab (HY-P9906)-induced cell death. Rolipram inhibits the expression of proinflammatory cytokines and enhances central noradrenergic transmission. Rolipram is mainly used in studies related to various central nervous system diseases including Alzheimer's disease, major depressive disorder, glioblastoma multiforme, and multiple sclerosis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900. MedChemExpress MCE
Rolipram (4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone) A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 13
Worldwide
Rolipram (Standard) Rolipram (Standard) is the analytical standard of Rolipram (HY-16900). This product is intended for research and analytical applications. Rolipram is a PDE4 inhibitor, with blood-brain barrier permeability, that reverses β-amyloid-induced learning and memory impairment in rats. Rolipram elevates intracellular cAMP and clevels and regulates the cAMP/CREB signaling pathway, thereby alleviating neuroinflammation and apoptotic responses. Rolipram promotes neuronal differentiation of human bone marrow mesenchymal stem cells and inhibits Methamphetamine- and morphine-induced hyperlocomotion in mice. Rolipram also reduces the viability of glioblastoma stem-like cells and enhances Bevacizumab (HY-P9906)-induced cell death. Rolipram inhibits the expression of proinflammatory cytokines and enhances central noradrenergic transmission. Rolipram is mainly used in studies related to various central nervous system diseases including Alzheimer's disease, major depressive disorder, glioblastoma multiforme, and multiple sclerosis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (R,S)-Rolipram (Standard); (±)-Rolipram (Standard); ZK 62711 (Standard). CAS No. 61413-54-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16900R. MedChemExpress MCE
Rolistobart Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2723442-10-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990092. MedChemExpress MCE
Rolitetracycline Rolitetracycline is a highly soluble, broad-spectrum antibiotic derived from tetracycline. Rolitetracycline binds to and stabilizes bovine serum albumin, and also inhibits HIV-1 integrase, blocks Aβ fibril formation and suppresses dengue virus proliferation. Rolitetracycline mediates the inhibition of Aβ fibrils via a specific three-dimensional pharmacophore conformation, and exerts bacteriostatic and bactericidal activities. Rolitetracycline acts synergistically with Penicillin G (HY-N7139) or Cephalothin (HY-B1275A) to alter the effects on microbial growth. Rolitetracycline serves as an important tool compound for the study of bacterial infections (urinary tract infections, sepsis), HIV-1 and dengue virus infections, as well as Alzheimer's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 751-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-18257. MedChemExpress MCE
Rolitetracycline Rolitetracycline is a semi-synthetic tetracycline antibiotic. It has broad-spectrum Gram-positive activity in the body. Uses: Antibacterial. Synonyms: Reverin; Syntetrin; Rolitetraciclina; Rolitetracyclinum; Pyrrolidino-Methyl-Tetracycline. Grade: >98% by HPLC. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.56. BOC Sciences
Rolitetracycline (Pyrrolidinyl methyl tetracycline, SQ 15659) Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable. Group: Biochemicals. Alternative Names: (4S, 4aS, 5aS, 6S, 12aS) -4- (di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; 4- (Di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; Abricycline; Bristacin; N- (1-Pyrrolidinylmethyl) tetracycline; N- (Pyrrolidinomethyl) tetracycline; Pyrrolidinyl methyl tetracycline; Reverin; Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin; Transcycline; Velacycline. Grades: Technical Grade. CAS No. 751-97-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 527.57. US Biological Life Sciences. USBiological 13
Worldwide
Rolofylline Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment.Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 (CYP450)[1].Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KW-3902. CAS No. 136199-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10965. MedChemExpress MCE
Romaciclib monohydrochloride SEL120-34A monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8. SEL120-34A monohydrochloride weakly inhibits CDK9 (calculated IC50=1070 nM), but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. SEL120-34A monohydrochloride inhibits phosphorylation of STAT1 S727 and STAT5 S726[1]. Has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SEL120-34A monohydrochloride. CAS No. 2443816-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111388A. MedChemExpress MCE
Romandolide® Romandolide®. CAS No. 236391-76-7. VIGON Item # 504005. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. Vigon
America & Internationally
Romascone® Romascone®. CAS No. 81752-87-6. VIGON Item # 502837. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, damascone carboxylate. Vigon
America & Internationally
R-Omeprazole R-Omeprazole. Uses: For analytical and research use. CAS No. 161796-77-6. Mole weight: 367.40. Catalog: AP161796776. Alfa Chemistry Analytical Products
Romidepsin Romidepsin Inhibitor. Uses: Scientific use. Product Category: T6006. CAS No. 128517-07-7. TARGETMOL CHEMICALS
Romidepsin Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Uses: For research used only. Synonyms: Istodax; FK228; FK 228; FK-228; Chromadax; Antibiotic FR 901228; FR901228; FR-901228; NSC-630176; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide. Grade: >98%. CAS No. 128517-07-7. Molecular formula: C24H36N4O6S2. Mole weight: 540.69. BOC Sciences
Romidepsin Romidepsin. Group: Biochemicals. Alternative Names: (1S,4Z,7S,10S,11E,20R)-4-Ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3, 6, 18, 21-tetrazabicyclo[8. 7. 6]tricos-11-ene-2, 5, 8, 19, 22-pentone; Depsipeptide; FK228. Grades: Highly Purified. CAS No. 128517-07-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H36N4O6S2. US Biological Life Sciences. USBiological 13
Worldwide
Romidepsin Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively[1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FK 228; FR 901228; NSC 630176. CAS No. 128517-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15149. MedChemExpress MCE
Romidepsin (FK228) Romidepsin (FK228, Depsipeptide, FR 901228, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM in cell-free assays, respectively. Romidepsin (FK228 / depsipeptide) controls growth and induces apoptosis in neuroblastoma tumor cells. Group: Inhibitors. Alternative Names: FK228, Depsipeptide, FR 901228, NSC 630176. CAS No. 128517-07-7. Pack Sizes: 10mg. Product ID: S3020. Formula: C24H36N4O6S2. Smiles: CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C. Storage Conditions: 2 years -80 in solvent. Selleck Chemicals
United States; Europe
Romiplostim Romiplostim is an Fc-peptide fusion protein mimetic of TPO (thrombopoietin protein) and also a c-Mpl agonist. Romiplostim binds to c-Mpl, stimulates megakaryocyte-mediated thrombopoiesis, and activates the same downstream signaling pathways as endogenous TPO. Romiplostim is applicable to research related to hematopoietic acute radiation syndrome and chronic immune thrombocytopenia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 267639-76-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990685. MedChemExpress MCE
Romosozumab Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: AMG-785; CDP-7851. CAS No. 909395-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P9982. MedChemExpress MCE
Romurtide Romurtide (Muroctasin) is a non-specific immune stimulant. Synonyms: MDP-Lys (L18); muroctasin. CAS No. 78113-36-7. Molecular formula: C43H78N6O13. Mole weight: 887.11. BOC Sciences 11
r-Ondansentron hydrochloride r-Ondansentron hydrochloride. CAS No. 146844-89-5. Product ID: ACM146844895. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 5
Rondonin Rondonin is an antibacterial peptide isolated from Acanthoscurria rondoniae (Spider). It has activity against fungi. Synonyms: Ile-Ile-Ile-Gln-Tyr-Glu-Gly-His-Lys-His. Grade: >96%. Molecular formula: C57H88N16O15. Mole weight: 1237.42. BOC Sciences 11

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