A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Roflurane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: bromo-2-trifluoro-1,1,2-ethyl-methyl ether; DA-893; Methyl-<1,1,2-trifluor-2-brom-aethyl>-aether; Ethane,2-bromo-1,1,2-trifluoro-1-methoxy; 1,1,2-Trifluor-2-bromethylmethylether; Rofluranum; Roflurano; Rofluran; 1,1,2-trifluoro-2-bromoethyl ether; R. Product Category: Heterocyclic Organic Compound. CAS No. 679-90-3. Molecular formula: C3H4BrF3O. Mole weight: 192.962. Purity: 0.96. IUPACName: 2-bromo-1,1,2-trifluoro-1-methoxyethane. Canonical SMILES: COC(C(F)Br)(F)F. Density: 1.687g/cm³. Product ID: ACM679903. Alfa Chemistry ISO 9001:2015 Certified.
Rogaratinib
Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100019.
Rogaratinib
Rogaratinib is a pan inhibitor of human fibroblast growth factor receptors (FGFRs). It reduced proliferation in FGFR-addicted cancer cell lines of various cancer types including lung, breast, colon and bladder cancer. Synonyms: BAY-1163877; BAY 1163877; BAY1163877. CAS No. 1443530-05-9. Molecular formula: C23H26N6O3S. Mole weight: 466.6.
Roginolisib
Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC 50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827.
Rohinitib
Rohinitib is a potent and specific eIF4A inhibitor. Rohinitib induces cell apoptosis of acute myeloid leukemia (AML) cell lines and reduces the leukemia burden of AML xenograft model. Rohinitib can be used for the research of AML[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1139253-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148422.
Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751.
Rolapitant
Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[45]decan-2-one; SCH619734; SCH-619734; SCH 619734; Varubi. Grades: >95%. CAS No. 552292-08-7. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1R,2R,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453123; EX-A1288F; Rolapitant (1R,2R,3R)-Isomer; FIVSJYGQAIEMOC-XARZLDAJSA-N; (5R, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-26-0. Grades: > 95%. CAS No. 1214741-26-0. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1R,2R,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453121; EX-A1288E; Rolapitant (1R,2R,3S)-Isomer; FIVSJYGQAIEMOC-AVIJNYRZSA-N; (5S, 8R) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-25-9. Grades: > 95%. CAS No. 1214741-25-9. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1R,2S,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL12679453; EX-A1288G; Rolapitant (1R,2S,3R)-Isomer; FIVSJYGQAIEMOC-UZFJHSOTSA-N; (5R, 8S) -8-[[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 552292-73-6. Grades: > 95%. CAS No. 552292-73-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2R,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Grades: > 95%. CAS No. 1214741-30-6. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2R,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453127; EX-A1288D; Rolapitant (1S,2R,3S)-Isomer; FIVSJYGQAIEMOC-FNVCAUGXSA-N; (5S, 8R) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-28-2. Grades: > 95%. CAS No. 1214741-28-2. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2S,3R)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: Rolapitant (1S,2S,3R)-Isomer. Grades: > 95%. CAS No. 1214741-29-3. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant (1S,2S,3S)-Isomer
An impurity of Rolapitant.Rolapitant is a selective NK1 receptor antagonist (antagonist for the NK1 receptor). Synonyms: SCHEMBL15453126; EX-A1288H; Rolapitant (1S,2S,3S)-Isomer; FIVSJYGQAIEMOC-PBNUPURSSA-N; HMS3750I21; (5S, 8S) -8-[[ (1S) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]methyl]-8-phenyl-1, 9-diazaspiro[4. 5]decan-2-one; 1214741-27-1. Grades: > 95%. CAS No. 1214741-27-1. Molecular formula: C25H26F6N2O2. Mole weight: 500.49.
Rolapitant HCl hydrate
Rolapitant, also known as SCH-619734, is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor antagonist with potential antiemetic activity. Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and late-phase CINV during the first 120 hours post-chemotherapy. Synonyms: (5S, 8S) -8- ( ( (R) -1- (3, 5-bis (trifluoromethyl) phenyl) ethoxy) methyl) -8-phenyl-1, 7-diazaspiro[4. 5]decan-2-one hydrochloride.; SCH619734 SCH-619734; SCH 619734; Rolapitant HCl; Rolapitant hydrochloride, Rolapitant, brand name: Varubi. CAS No. 914462-92-3. Molecular formula: C25H26F6N2O2.ClH.H2O. Mole weight: 554.95.
Rolapitant hydrochloride hydrate
Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734 hydrochloride hydrate. CAS No. 914462-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16436.
Roletamide
Roletamide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Roletamide;3-(2,5-Dihydro-1H-pyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one;CL 59112. Product Category: Heterocyclic Organic Compound. CAS No. 10078-46-3. Molecular formula: C16H19NO4. Purity: 0.96. IUPACName: (E)-3-(2,5-dihydropyrrol-1-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)C=CN2CC=CC2. Density: 1.203g/cm³. Product ID: ACM10078463. Alfa Chemistry ISO 9001:2015 Certified.
Rolinsatamab
Rolinsatamab is a humanized bispecific monoclonal antibody targeting both IL-4 and IL-13. CAS No. 2095467-30-2.
Rolipram
Rolipram. Group: Biochemicals. Grades: Purified. CAS No. 61413-54-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Rolipram
Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC 50 s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900.
Rolipram is a selective PDE4 inhibitor that modulates cyclic AMP (cAMP) degradation. Study showed that rolipram induced neuronal differentiation of human bone marrow-mesenchymal stem cells (hBM-MSCs). It can be used as an anti-inflammatory agent. Uses: Antidepressive agents. Synonyms: ZK-62711; SB 95952; 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one. Grades: >98%. CAS No. 61413-54-5. Molecular formula: C16H21NO3. Mole weight: 275.34.
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=800nM). A rolipram-insensitive PDE IV subtype is also known to exist. Also inhibits NF-kB and NFAT activation in Jurkat and primary T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 61413-54-5. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Rolipram - CAS 61413-54-5
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 800 nM). Group: Fluorescence/luminescence spectroscopy.
rolitetracycline
Rolitetracycline is a semi-synthetic tetracycline antibiotic. It has broad-spectrum Gram-positive activity in the body. Uses: Antibacterial. Synonyms: Reverin; Syntetrin; Rolitetraciclina; Rolitetracyclinum; Pyrrolidino-Methyl-Tetracycline. Grades: >98% by HPLC. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.56.
Rolitetracycline
Rolitetracycline, a derivative of tetracycline, is a broad-spectrum antibiotic [1] [2]. Rolitetracyclin has a role as a protein synthesis inhibitor, an antiprotozoal agent and a proagent [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 751-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-18257.
Rolitetracycline
Rolitetracycline. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 12,12a-pentahydroxy-6-methyl-1,11-dioxo-n-(1-pyrrolidinylmethyl)-1;bristacin;n-(1-pyrrolidinylmethyl)-tetracycline;n-(pyrrolidinomethyl)tetracycline;pirrolidinometil-tetraciclina;prm-tc;pyrrolidinomethyl-tetracyclin;pyrrolidino-methyl-tetracycline. Product Category: Heterocyclic Organic Compound. CAS No. 751-97-3. Molecular formula: C27H33N3O8. Mole weight: 527.57. Product ID: ACM751973. Alfa Chemistry ISO 9001:2015 Certified.
Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable. Group: Biochemicals. Alternative Names: (4S, 4aS, 5aS, 6S, 12aS) -4- (di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; 4- (Di methyl amino) -1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-6- methyl -1, 11-dioxo-N- (1-pyrrolidinyl methyl ) -2-naphthacene carboxamide; Abricycline; Bristacin; N- (1-Pyrrolidinylmethyl) tetracycline; N- (Pyrrolidinomethyl) tetracycline; Pyrrolidinyl methyl tetracycline; Reverin; Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin; Transcycline; Velacycline. Grades: Technical Grade. CAS No. 751-97-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 527.57. US Biological Life Sciences.
Worldwide
Rolofylline
Rolofylline (KW-3902) is a potent, selective adenosine A1 receptor antagonist that is under development for the treatment of patients with acute congestive heart failure and renal impairment. Rolofylline is metabolized primarily to the pharmacologically active M1-trans and M1-cis metabolites by cytochrome P450 ( CYP 450 ) [1]. Rolofylline is alleviating the presynaptic dysfunction and restores neuronal activity as well as dendritic spine levels in vitro, is an interesting candidate to combat the hypometabolism and neuronal dysfunction associated with Tau-induced neurodegenerative diseases [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KW-3902. CAS No. 136199-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10965.
Rolofylline metabolite M1-cis
Rolofylline metabolite M1-cis, an active metabolite of Rolofylline, is a potent and selective adenosine A1 receptor antagonist. Synonyms: Rolofylline metabolite M1-cis; Rolofylline metabolite M1-trans; 160943-06-6; 161167-65-3; SCHEMBL3263501; L011792; 8-(Hexahydro-7-hydroxy-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-1H-Purine-2,6-dione, cis; 8-(Hexahydro-7-hydroxy-2,5-methanopentalen-3a(1H)-yl)-3,9-dihydro-1,3-dipropyl-1H-Purine-2,6-dione, trans. Grades: 98%. CAS No. 161167-65-3. Molecular formula: C20H28N4O3. Mole weight: 372.46.
Rolofylline metabolite M1-trans
Rolofylline metabolite M1-trans, an active metabolite of Rolofylline, is a potent and selective adenosine A1 receptor antagonist. Grades: 99%. CAS No. 160943-06-6. Molecular formula: C20H28N4O3. Mole weight: 372.46.
Roluperidone
Roluperidone (CYR-101) is a novel cyclic amide derivative that has high equipotent affinities for 5-HT 2A and sigma-2 receptors ( K i of 7.53 nM and 8.19 nM for 5-HT 2A and sigma-2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CYR-101; MIN-101; MT-210. CAS No. 359625-79-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19469.
Romaciclib monohydrochloride
SEL120-34A monohydrochloride is an ATP-competitive and selective CDK8 inhibitor, inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50s of 4.4 nM and 10.4 nM, respectively, with a Kd of 3 nM for CDK8. SEL120-34A monohydrochloride weakly inhibits CDK9 (calculated IC50=1070 nM), but shows no obvious activity against CDK1, 2, 4, 6, 5, 7. SEL120-34A monohydrochloride inhibits phosphorylation of STAT1 S727 and STAT5 S726[1]. Has anti-tumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SEL120-34A monohydrochloride. CAS No. 2443816-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111388A.
Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively. Uses: For research used only. Synonyms: Istodax; FK228; FK 228; FK-228; Chromadax; Antibiotic FR 901228; FR901228; FR-901228; NSC-630176; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide. Grades: >98%. CAS No. 128517-07-7. Molecular formula: C24H36N4O6S2. Mole weight: 540.69.
Romidepsin
Romidepsin. Group: Biochemicals. Alternative Names: (1S,4Z,7S,10S,11E,20R)-4-Ethylidene-7,20-dipropan-2-yl-9-oxa-15,16-dit hia-3, 6, 18, 21-tetrazabicyclo[8. 7. 6]tricos-11-ene-2, 5, 8, 19, 22-pentone; Depsipeptide; FK228. Grades: Highly Purified. CAS No. 128517-07-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H36N4O6S2. US Biological Life Sciences.
Worldwide
Romidepsin
Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC 50 s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively [1]. Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK 228; FR 901228; NSC 630176. CAS No. 128517-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15149.
Romifidine is an α 2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 65896-16-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-119456.
Romifidine
Romifidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Romifidine;2-(2-Bromo-6-fluoroanilino)-2-imidazoline;Romidys;St 2130;STH 2130. Product Category: Heterocyclic Organic Compound. CAS No. 65896-16-4. Molecular formula: C9H9BrFN3. Mole weight: 258.093. Product ID: ACM65896164. Alfa Chemistry ISO 9001:2015 Certified.
Romifidine hydrochloride
Romifidine is an α2 agonist used as a sedative and analgesic in horses. Synonyms: N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride; STH 2130Cl; Sedivet. CAS No. 65896-14-2. Molecular formula: C9H10BrClFN3. Mole weight: 294.55.
Romiplostim
Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2626841-92-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990685.
Romlusevimab
Romlusevimab (BRII-198) is a neutralizing recombinant human IgG1 monoclonal antibody against the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BRII-198. CAS No. 2509447-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99889.
Romosozumab
Romosozumab is a humanized monoclonal anti-sclerostin antibody , it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 909395-70-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9982.
Romosozumab
Romosozumab is a humanized monoclonal antibody indicated for the treatment of osteoporosis in postmenopausal women at high risk of fracture. Romosozumab binds to and inhibits sclerostin, promoting the activation of the Wnt/β-catenin pathway that normally stimulates osteoblasts. Synonyms: Evenity. CAS No. 909395-70-6.
Romurtide
Romurtide (Muroctasin) is a non-specific immune stimulant. Synonyms: MDP-Lys (L18); muroctasin. CAS No. 78113-36-7. Molecular formula: C43H78N6O13. Mole weight: 887.11.
Ronacaleret is a calcium-sensing receptor (CaSR) antagonist under the development of GlaxoSmithKline. It is potential for therapeutic utility in the stimulation of PTH release, notably as a bone anabolic agent comparable to recombinant human PTH(1-34). In Jul 2015, Phase-II for Stem cell mobilisation in USA was discontinued. In Mar 2016, Phase-I for Postmenopausal osteoporosis (In volunteers) in USA was discontinued. Uses: Postmenopausal osteoporosis; stem cell mobilisation. Synonyms: SB 751689; SB751689; SB-751689; (R)-3-(3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)-4,5-difluorophenyl)propanoic acid;753449-67-1 (HCl salt). Grades: 98%. CAS No. 753449-67-1. Molecular formula: C25-H31-F2-N-O4. Mole weight: 447.52.
Ronacaleret hydrochloride
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroid hormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 751689A. CAS No. 702686-96-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15104.
Rondonin
Rondonin is an antibacterial peptide isolated from Acanthoscurria rondoniae (Spider). It has activity against fungi. Synonyms: Ile-Ile-Ile-Gln-Tyr-Glu-Gly-His-Lys-His. Grades: >96%. Molecular formula: C57H88N16O15. Mole weight: 1237.42.
Roniciclib
Roniciclib is an orally bioavailable pan-cyclin dependent kinase (CDK) inhibitor, with IC50s of 5-25 nM for CDK1, CDK2, CDK3, CDK4, CDK7 and CDK9. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1000394. CAS No. 1223498-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13914.
Roniciclib
Roniciclib, also known as BAY 1000394, is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. BAY1000394 selectively binds to and inhibits the activity of CDK1/Cyclin B, CDK2/Cyclin E, CDK4/Cyclin D1, and CDK9/Cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle progression and cellular proliferation. Synonyms: BAY10-00394; BAY1000394; BAY 1000394; NSC774911; (2R, 3R) -3-{[2-{[4- (S-Cyclopropylsulfonimidoyl) phenyl]amino}-5- (trifluoromethyl) -4-pyrimidinyl]oxy}-2-butanol; 2-Butanol, 3-[[2-[[4- (S-cyclopropylsulfonimidoyl) phenyl]amino]-5- (trifluoromethyl) -4-pyrimidinyl]oxy]-, (2R,3R)-. Grades: ≥98%. CAS No. 1223498-69-8. Molecular formula: C18H21F3N4O3S. Mole weight: 430.44.
Ronidazole
Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7681-76-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0565.
Ronidazole
25g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C6H8N4O4. CAS No. 7681-76-7. Prepack ID 90026995-25g. Molecular Weight 200.15. See USA prepack pricing.
analytical standard. Group: Application areaspharma & vet compounds & metabolitesstable isotope labelled compoundspharma & vet compounds & metabolitesstable isotope labelled compounds. Alternative Names: Ronidazole D3.
Ronidazole (Standard)
Ronidazole (Standard) is the analytical standard of Ronidazole. This product is intended for research and analytical applications. Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7681-76-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0565R.
Ronomilast
Ronomilast is type 4 cyclic nucleotide phosphodiesterase inhibitor for the treatment of chronic obstructive pulmonary disease (COPD). Uses: Type 4 cyclic nucleotide phosphodiesterase inhibitor. Synonyms: AWD 12353; AWD12353; AWD-12353; ELB353; ELB-353; ELB 353; Elbimilast; Ronomilast.N-(3,5-dichloropyridin-4-yl)-2-(1-(4-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-oxoacetamide. Grades: ≥98%. CAS No. 418794-42-0. Molecular formula: C21H13Cl2FN4O2. Mole weight: 443.25.
Ronopterin
Ronopterin is a potent Nitric oxide synthase inhibitor used as a neuroprotectant. Synonyms: VAS-203; VAS 203; VAS203; Ronopterin; (1R,2S)-1-[(6R)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol; 4-aminotetrahydrobiopterin. Grades: >98%. CAS No. 206885-38-3. Molecular formula: C9H16N6O2. Mole weight: 240.27.
Rontalizumab
Rontalizumab is a humanized IgG1 monoclonal antibody targets IFN-&alpha. Rontalizumab can be used for the research of systemic lupus erythematosus[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RhuMab IFNalpha; Anti-Human IFN alpha Recombinant Antibody. CAS No. 948570-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99267.
Rooibos CO2 Extract
Rooibos CO2 Extract. CAS No. MIXTURE. Kosher: Y. VIGON Item # 504850. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils.
America & Internationally
Rooibos Milled Powder (Aspalathus Linearis)
Rooibos Milled Powder (Aspalathus Linearis).
CA, FL & NJ
Ropeginterferon alfa-2b
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b. CAS No. 1335098-50-4. Pack Sizes: 250 μg. Product ID: HY-P99348.
Ropidoxuridine
Ropidoxuridine is a novel, orally available 5-substituted 2-pyrimidinone-2'-deoxyribonucleoside analogue and prodrug of 5-iododeoxyuridine (IUdR). It has radiosensitizing activity. It is efficiently converted to idoxuridine (IUdR) by a hepatic aldehyde oxidase. It is incorporated into DNA during replication, thereby sensitizing cells to ionizing radiation by increasing DNA strand breaks. It is associated with a lower toxicity profile and improved anti-tumor activity. It has dose responsive and synergistic effects. It has also shown reduced toxicity, with better tissue incorporation and improved anti-tumor activity. It maybe used to treat colorectal, gastric, and pancreatic cancer, and other solid tumors. Uses: Ropidoxuridine has radiosensitizing activity. it maybe used to treat colorectal, gastric, and pancreatic cancer, and other solid tumors. Synonyms: IPdR; D08992; Ropidoxuridine; 5-Iodo-2-pyrimidinone-2-deoxyribose. 1-(2-deoxy-beta-ribofuranosyl)-5-iodo-2-pyrimidinone;5-Iodo-2-pyrimidinone-2'-deoxyribose;IPdR;1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one. Grades: >98 %. CAS No. 93265-81-7. Molecular formula: C9H11IN2O4. Mole weight: 338.10.