A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Rp-8-Br-PET-cGMPS is a selective inhibitor of cGMP-dependent protein kinase I a and I β and of retinal cGMP-gated ion channels. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-pCPT-cGMPS, it is much more lipophilic and membrane-permeant. Alternative Names: 8- Bromo- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 172806-20-1. Molecular formula: C18H14BrN5O6PS · Na. Mole weight: 562.3.
Rp-8-Br-PET-cGMPS
Rp-8-Br-PET-cGMPS. Group: Biochemicals. Grades: Purified. CAS No. 185246-32-6. Pack Sizes: 560ug. US Biological Life Sciences.
Worldwide
Rp-8-Cl-cAMPS
Rp-8-Cl-cAMPS is a selective and competitive inhibitor of protein kinase A (cAMP antagonist) preferring type I of protein kinase A. It inhibits mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- Chloroadenosine- 3', 5'- monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 142754-27-6. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7.
Rp-8-CPT-cAMPS
Rp-8-CPT-cAMPS is an analog of Rp-cAMPS and a competitive inhibitor of protein kinase A type I and II (cAMP antagonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-8-Br-cAMPS, it is more lipophilic and membrane-permeant. Alternative Names: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129735-01-9. Molecular formula: C16H14ClN5O5PS2 · Na. Mole weight: 509.8.
Rp-8-OH-cAMPS
Rp-8-OH-cAMPS is a polar analogue of Rp-cAMPS, the protein kinase A inhibitor, used for the study of extracellular cAMP receptors. It inhibits mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 475084-30-1. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
Rp-8-pCPT-cGMPS
Rp-8-pCPT-cGMPS is a selective inhibitor of protein kinase G I a, I ß and especially of type II, which stimulates retinal cGMP channels and discriminates between kinase and channel effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-cGMPS or Rp-8-Br-cGMPS, it exhibits more lipophilic and membrane-permeant properties. Alternative Names: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-04-9. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9.
Rp-8-pCPT-PET-cGMPS
Rp-8-pCPT-PET-cGMPS is an inhibitor of protein kinase G and probably of retinal cGMP-gated ion channels. It has a resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- (4- Chlorophenylthio)-β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 1262749-62-1. Molecular formula: C24H18ClN5O6PS2 · Na. Mole weight: 626.
Rp-8-PIP-cAMPS
Rp-8-PIP-cAMPS is a selective analogue of Rp-cAMPS, the protein kinase A inhibitor, preferring site B of cAK type II. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-cAMPS, it has more lipophilic and membrane-permeant properties. Alternative Names: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 156816-36-3. Molecular formula: C15H20N6O5PS · Na. Mole weight: 450.4.
Rp-Adenosine 3,5-cyclic monophosphorothioate triethylammonium salt
Rp-Adenosine 3,5-cyclic monophosphorothioate triethylammonium salt. Uses: For analytical and research use. CAS No. 151837-09-1 (anhydrous). Mole weight: 446.46. Catalog: ALP151837091.
Rp-cAMPS sodium salt
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis by phosphodiesterases[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142439-94-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100530D.
Rp-cAMPS, sodium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II (cAMP antagonist), which has a higher affinity for type II of protein kinase A. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Uses: Protein kinase inhibitors. Alternative Names: Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 73208-40-9. Molecular formula: C10H11N5O5PS · Na. Mole weight: 367.3.
Rp-cAMPS, triethyl ammonium salt
Rp-cAMPS is a competitive inhibitor of protein kinase A type I and II, the cAMP antagonist, which has high selectivity of type II of protein kinase A. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Uses: Protein kinase inhibitors. Alternative Names: Adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, triethyl ammonium salt. Grades: ≥ 98% by HPLC. CAS No. 151837-09-1. Molecular formula: C10H11N5O5PS · C6H16N. Mole weight: 446.5.
Rp-cCMPS
Rp-cCMPS is a PDE-resistant cCMP, the potential second messenger, which inhibits cCMP-binding proteins. Alternative Names: Cytidine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 87063-79-4. Molecular formula: C9H11N3O6PS · Na. Mole weight: 343.2.
Rp-c-diAMPS
Rp-c-diAMPS is an analogue of c-diAMP, the bacterial second messenger. Alternative Names: Cyclic diadenosine monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O11P2S (free acid). Mole weight: 674.5 (free acid).
Rp-c-diGMPS
Rp-c-diGMPS is an analogue of c-diGMP, the bacterial second messenger, which can be used to study ligand-receptor interactions. Alternative Names: Cyclic diguanosine monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-32-5. Molecular formula: C20H24N10O13P2S (free acid). Mole weight: 706.5 (free acid).
Rp-cGMPS
Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low. Alternative Names: Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 86562-09-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
Rp-dUTP-α-S
Rp-dUTP-α-S is a paramount instrument assuming a pivotal role in substrate allocation for enzymatic facilitation of DNA replication and repair mechanisms. Its utility extends to the elucidation of potential pharmaceutical targets by means of DNA sequencing and labeling techniques. Alternative Names: 2'- Deoxyuridine- 5'- O- (1- thiotriphosphate), Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 876068-86-9. Molecular formula: C9H15N2O13P3S (free acid). Mole weight: 484.2 (free acid).
Rp-GDP-α-S
Rp-GDP-α-S is a GDP binding proteins regulator with high stability, which is used for characterization of GDP-responsive receptors and determination of their stereospecificity. Alternative Names: Guanosine- 5'- O- (1- thiodiphosphate), Rp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 71481-44-2. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.3 (free acid).
The enzyme, characterized from the cyanobacterium Synechococcus sp. WH8102, catalyses the covalent attachment of the phycobilin chromophore phycoerythrobilin to cysteine 84 of the α subunit of the phycobiliprotein R-phycocyanin and its isomerization to phycourobilin.
The enzyme, characterized from the cyanobacterium Synechococcus sp. WH8102, catalyses the covalent attachment of the phycobilin chromophore phycoerythrobilin to cysteine 84 of the α subunit of the phycobiliprotein R-phycocyanin and its isomerization to phycourobilin. Group: Enzymes. Synonyms: rpcG (gene name). Enzyme Commission Number: EC 4.4.1.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5336; R-phycocyanin α-cysteine-84 phycourobilin lyase/isomerase; EC 4.4.1.33; rpcG (gene name). Cat No: EXWM-5336.
R-Phycoerythrin
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm). Uses: Scientific research. Category: Signaling pathways. Alternative Names: R-PE. CAS No. 11016-17-4. Pack Sizes: 1 mg (20 mg * mL * 50 μL in buffer (buffer containing 60% (NH4)2SO4)); 5 mg (20 mg * mL * 250 μL in buffer (buffer containing 60% (NH4)2SO4)); 10 mg (20 mg * mL * 500 μL in buffer (buffer containing 60% (NH4)2SO4)). Product ID: HY-D0988.
RPI856 A
RPI856 A is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Alternative Names: RPI856A; RPI-856 A. Molecular formula: C43H61N7O13. Mole weight: 884.
RPI856 B
RPI856 B is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Alternative Names: RPI856B; RPI-856 B. Molecular formula: C43H61N7O13. Mole weight: 884.
RPI856 C
RPI856 C is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Alternative Names: RPI856Cl RPI-856 C. Molecular formula: C39H56N6O10. Mole weight: 768.9.
RPI856 D
RPI856 D is a retrovirus protease inhibitor produced by Streptomyces sp. AL-322. It strongly inhibits in vitro HIV-1 protease and HTLV-I protease both derived from recombinant Escherichia coli. Alternative Names: RPI856D; RPI-856 D. Molecular formula: C39H56N6O10. Mole weight: 768.9.
R)-(+)-Piperazine-2-carboxylic acid
5g Pack Size. Group: Building Blocks, Chiral Compounds, Organics, Piperazines. Formula: C5H10N2O2. CAS No. 31321-68-3. Prepack ID 59717481-5g. Molecular Weight 130.15. See USA prepack pricing.
5g Pack Size. Group: Building Blocks, Chiral Compounds, Pyrazines. Formula: C5H12Cl2N2O2. CAS No. 126330-90-3. Prepack ID 11959793-5g. Molecular Weight 203.07. See USA prepack pricing.
RPL-554
RPL 554 is a potent and selective PDE3/4 inhibitor for respiratory diseases, particularly in patients with asthma. Uses: A potent and selective pde3/4 inhibitor. Alternative Names: [2-[6,7-Dihydro-9,10-dimethoxy-4-oxo-2-[(2,4,6-trimethylphenyl)imino]-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl]ethyl]-urea;UNII-3E3D8T1GIX;RPL-554; RPL-554; RPL-554; LS-193,855; LS 193,855; LS 193,855; LS193855; LS193855; LS-193855. Grades: ≥96%. CAS No. 298680-25-8. Molecular formula: C26H31N5O4. Mole weight: 477.56.
RPL8 protein (31-41)
RPL8 protein (31-41) is a truncated fragment of RPL8 protein. RPL8 (Ribosomal Protein L8) is a Protein Coding gene. Diseases associated with RPL8 include Spermatogenic Failure 2 and Spermatogenic Failure 1. Among its related pathways are Viral mRNA Translation and HIV Life Cycle. Alternative Names: Ribosomal Protein L8 (31-41).
RPR113228
RPR113228 is a farnesyl-protein transferase inhibitor produced by Chrysosporium lobatum. It has no inhibitory effect on squalene synthase. Alternative Names: RPR-113228; RPR113228. Molecular formula: C30H49O9P. Mole weight: 584.7.
RPR121056
RPR121056 (APC) is a metabolite of Irinotecan (CPT-11), which is generated by CYP3A4. Irinotecan (CPT-11) is an antineoplastic agent that inhibits topoisomerase type I, causing cell death, and is widely used in the treatment of colorectal cancer. Irinotecan also directly inhibits AChE[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APC. CAS No. 181467-56-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100620.
RPR-260243
RPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel[1][2]. RPR-260243 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 668463-35-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16915.
R-Pralatrexate
The R isometric form of Pralatrexate which is a folate analog used to treat relapsed or refractory peripheral T-cell lymphoma. Alternative Names: Pralatrexate, (R)-; (R)-pralatrexate; 1320211-70-8; UNII-9CY33O2XLX; 9CY33O2XLX; L-Glutamic acid, N-(4-((1R)-1-((2,4-diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-; 1320211-70-8 (R-isomer); (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid; SCHEMBL1889869; DTXSID001031315; AKOS040747299; PD132342; HY-117791; CS-0068078; Q27272363; (2S)-2-[[4-[(2R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid. Grades: > 95%. CAS No. 1320211-70-8. Molecular formula: C23H23N7O5. Mole weight: 477.48.
RprDefA
RprDefA is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Alternative Names: R. prolixus defensin A; Ala-Thr-Cys-Asp-Leu-Phe-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Ala-Cys-Ala-Ala-His-Cys-Leu-Leu-Arg-Gly-Asn-Arg-Gly-Gly-Arg-Cys-Lys-Gly-Thr-Ile-Cys-His-Cys-Arg-Lys. Molecular formula: C200H322N70O53S6. Mole weight: 4747.51.
RprDefB
RprDefB is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Alternative Names: R. prolixus defensin B; Ala-Thr-Cys-Asp-Leu-Leu-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Gly-Cys-Ala-Ala-His-Cys-Leu-Leu-Arg-Gly-Asn-Arg-Gly-Gly-His-Cys-Lys-Gly-Thr-Ile-Cys-His-Cys-Arg-Lys. Molecular formula: C196H317N69O53S6. Mole weight: 4680.46.
RprDefC
RprDefC is an antibacterial peptide isolated from Rhodnius prolixus. It has activity against gram-positive bacteria and gram-negative bacteria, and can also be used as an insecticide. Alternative Names: R. prolixus defensin C; Ala-Thr-Cys-Asp-Leu-Phe-Ser-Phe-Arg-Ser-Lys-Trp-Val-Thr-Pro-Asn-His-Ala-Gly-Cys-Ala-Ala-His-Cys-Ile-Phe-Leu-Gly-Asn-Arg-Gly-Gly-Arg-Cys-Val-Gly-Thr-Val-Cys-His-Cys-Arg-Lys. Molecular formula: C200H312N66O53S6. Mole weight: 4681.45.
Rp,Rp-c-diAMPSS
Rp,Rp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions and to increase the anti-tumor activity of therapeutic vaccines. Alternative Names: Cyclic diadenosine monophosphorodithioate, Rp- isomers, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid).
Rp,Rp-c-diGMPSS
Rp,Rp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions. Alternative Names: Cyclic diguanosine monophosphorodithioate, Rp- isomers, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-41-6. Molecular formula: C20H24N10O12P2S2 (free acid). Mole weight: 722.6 (free acid).
R-PSOP
R-PSOP is highly potent and selective nonpeptidic NMUR2 antagonist. R-PSOP binds to NMUR2 with the Kis of 52 and 32 nM for the human and rat NMUR2, respectively. R-PSOP shows moderate CNS penetration. R-PSOP can be used for the research of the eating disorders, obesity, pain, and stress-related disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1185189-97-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145086.
Rp,Sp-c-diAMPSS
Rp,Sp-c-diAMPSS is an analogue of c-diAMP, the bacterial second messenger, which has higher stability. It can be used to study ligand-receptor interactions. Alternative Names: Cyclic diadenosine monophosphorodithioate, Rp- / Sp- isomers, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O10P2S2 (free acid). Mole weight: 690.6 (free acid).
Rp,Sp-c-diGMPSS
Rp,Sp-c-diGMPSS is an analogue of c-diGMP, the bacterial second messenger, with improved stability. It can be used to study ligand-receptor interactions. Alternative Names: Cyclic diguanosine monophosphorodithioate, Rp- / Sp- isomers, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1259875-47-2. Molecular formula: C20H24N10O12P2S2 (free acid). Mole weight: 722.6 (free acid).
Rp-TTP-α-S
Rp-TTP-α-S is used for regulation of TTP-responsive receptors and determination of their stereospecificity. Compared to TTP, it is much more stable. Alternative Names: Thymidine- 5'- O- (1-thiotriphosphate), Rp-isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 83199-35-3. Molecular formula: C10H17N2O13P3S (free acid). Mole weight: 498.2 (free acid).
RPW-24
RPW-24 protects C. elegans from bacterial infection by stimulating the host immune response of the nematode. RPW-24 has antibacterial activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1001625-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W035409.
RQ 00203078
RQ 00203078. Group: Biochemicals. Grades: Purified. CAS No. 1254205-52-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RQ-00203078
RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively. RQ-00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1254205-52-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18662.
RR-11a
RR-11a is a synthetic enzyme inhibitor of Legumain (IC50=31-55 nM). RR-11a can be used for the research of cancer and acute myocardial infarction (AMI)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1361390-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112205.
RR-11a analog
RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 685543-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112205A.
RR6
RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1351758-37-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18780.
R-Rivaroxaban
5-R-Rivaroxaban is the R-isomer of Rivaroxaban, which is a novel, oral, direct Factor Xa (FXa) inhibitor. It is useful for antithrombotic agent and is a promising drug for atrial fibrillation, venous thromboembolism or thromboembolic disorders in clinic. Uses: 5-r-rivaroxaban is useful for antithrombotic agent and is a promising drug for atrial fibrillation, venous thromboembolism or thromboembolic disorders in clinic. Alternative Names: (R)-5-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide; 5-Chloro-N-({(5R)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide; BAY 59-7939; R-Rivaroxaban; ent-Rivaroxaban; Rivaroxaban R-Enantiomer; Rivaroxaban EP Impurity A. Grades: >98%. CAS No. 865479-71-6. Molecular formula: C19H18ClN3O5S. Mole weight: 435.88.
rRNA endonuclease
Also acts on bacterial rRNA. Group: Enzymes. Synonyms: α-sarcin. Enzyme Commission Number: EC 3.1.27.10. CAS No. 1407-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3599; rRNA endonuclease; EC 3.1.27.10; 1407-48-3; α-sarcin. Cat No: EXWM-3599.
rRNA N-glycosylase
Ricin A-chain and related toxins show this activity. Naked rRNA is attacked more slowly than rRNA in intact ribosomes. Naked rRNA from Escherichia coli is cleaved at a corresponding position. Group: Enzymes. Synonyms: ribosomal ribonucleate N-glycosidase; nigrin b; RNA N-glycosidase; rRNA N-glycosidase; ricin; momorcochin-S; Mirabilis antiviral protein; momorcochin-S; gelonin; saporins. Enzyme Commission Number: EC 3.2.2.22. CAS No. 113756-12-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3976; rRNA N-glycosylase; EC 3.2.2.22; 113756-12-0; ribosomal ribonucleate N-glycosidase; nigrin b; RNA N-glycosidase; rRNA N-glycosidase; ricin; momorcochin-S; Mirabilis antiviral protein; momorcochin-S; gelonin; saporins. Cat No: EXWM-3976.
rRNA small subunit pseudouridine methyltransferase Nep1
This enzyme, which occurs in both prokaryotes and eukaryotes, recognizes specific pseudouridine residues (ψ) in small subunits of ribosomal RNA based on the local RNA structure. It recognizes ψ914 in 16S rRNA from the archaeon Methanocaldococcus jannaschii, ψ1191 in yeast 18S rRNA, and ψ1248 in human 18S rRNA. Group: Enzymes. Synonyms: Nep1; nucleolar essential protein 1. Enzyme Commission Number: EC 2.1.1.260. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1865; rRNA small subunit pseudouridine methyltransferase Nep1; EC 2.1.1.260; Nep1; nucleolar essential protein 1. Cat No: EXWM-1865.
RR-RJW100
RR-RJW100, the enantiomer of RJW100, is an nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1) agonist. RJW100 can be synthesized as two enantiomers, RR-RJW100 and SS-RJW100, with RR-RJW100 shown to be the more potent LRH-1 agonist. RR-RJW100 is involved in the regulation of metabolic homeostasis and is used in studies of diabetes, liver disease and inflammatory bowel disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3127027-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131445B.
RR-src
RR-src. Group: Biochemicals. Grades: Purified. CAS No. 81156-93-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
RRx-001
RRx-001, a hypoxia-selective epigenetic agent and studied as a radio- and chem-sensitizer, triggers apoptosis and overcomes agent resistance in myeloma. RRx-001 exhibits potent anti-tumor activity with minimal toxicity[1]. RRx-001 is a dual small molecule checkpoint inhibitor by downregulating CD47 and SIRP-α[2]. RRx-001 is a potent inhibitor of G6PD and shows potent antimalarial activity[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Nibrozetone. CAS No. 925206-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16438.
RRX-001
RRX-001 is a dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy. Alternative Names: RRX001; RRX 001; RRx-001; ABDNAZ. CAS No. 925206-65-1. Molecular formula: C5H6BrN3O5. Mole weight: 268.02.
RS 09
RS 09 is an LPS (HY-D1056) peptide mimic and TLR4 agonist. RS 09 can bind to TLR-4 and activate NF-κB. RS 09 can function as an adjuvant in vivo, enhancing the antigen-specific immune response[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449566-36-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1439.
RS 09
RS 09 is a TLR4 agonist. Alternative Names: Ala-Pro-Pro-His-Ala-Leu-Ser; RS09; RS-09; L-Serine, L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-; L-Alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine. Grades: ≥95%. CAS No. 1449566-36-2. Molecular formula: C31H49N9O9. Mole weight: 691.78.
RS09 2TFA
RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment. Alternative Names: H-Ala-Pro-Pro-His-Ala-Leu-Ser-OH.2TFA; L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine trifluoroacetic acid; RS 09 2TFA. Grades: ≥95%. Molecular formula: C35H51F6N9O13. Mole weight: 919.82.
RS-1
High affinity RAD51 activator (Kd range = 48-107nM, value depends on cofactors present). Enhances homologous recombination activity of hRAD51. Enhances homology-directed repair and increases CRISPR-mediated knock-in efficiencies in vitro and in vivo.RS-1 is an activator of DNA repair protein RAD51 (Kd = 48-107 for human RAD51 with different cofactors present).1 It stimulates homologous strand assimilation activity at least 5- to 11-old, enhancing homologous recombination activity of hRAD51.1 RS-1 is a potent enhancer of CRISPR-mediated genome editing, increasing homology directed repair 3- to 6-fold.2 It is used to increase CRISPR-mediated knock-in efficiencies in vitro and in vivo.3,2,4. Group: Biochemicals. Alternative Names: 4-Bromo-N- (4-bromophenyl) -3- [ [ (phenylmethyl) amino] sulfonyl] benzamide. Grades: Highly Purified. CAS No. 312756-74-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C??H??Br?N?O?S, Molecular Weight: 524.23. US Biological Life Sciences.
Worldwide
RS-1
RS-1 is a RAD51 activator. RS-1 enhances the homologous recombination activity of human RAD51 by promoting the formation of active presynaptic filaments[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 312756-74-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19793.
RS 102895 hydrochloride
RS 102895 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1173022-16-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RS-127445
RS-127445 is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199864-87-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15419A.
RS 127445 hydrochloride
RS 127445 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 199864-86-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RS-127445 hydrochloride
RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist with a pKi of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199864-86-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15419.
RS 127445 Hydrochloride
A selective, high affinity , orally bioavailable 5-HT2B receptor antagonist. RS-127445 was found to have nanomolar affinity for the 5-HT2B receptor (pKi = 9.5) and 1,000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites including the closely related 5-HT2A and 5-HT2C receptors. In isolated human cells, RS-127445 exbhited an IC50 greater than 10uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 199864-86-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
RS17
RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPα, on the surface membrane of macrophages. The main regulatory mechanism of RS17 is to prevent CD47 from transmitting selective phagocytosis signals to SIRPα by binding to CD47, so that macrophages do not recognize tumor cells as their own tissue, but phagocytose them as foreign substances, thereby inhibiting immune escape of tumor cells. RS17 can be used to study the mechanism of anti-tumor response and immune escape[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2415545-08-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10420.
RS 17053 hydrochloride
RS 17053 hydrochloride is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RS-17053. CAS No. 169505-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-101336.
RS-22A
RS-22A is a macrolide antibiotic produced by Streptomyces violaceusniger. It is active against gram-positive, gram-negative bacteria, yeast and filamentous fungi. Alternative Names: RS-22 A. Molecular formula: C54H91N3O17. Mole weight: 1054.3.