A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Roxithromycin EP Impurity H. Uses: For analytical and research use. CAS No. 425365-65-7. Molecular formula: C41H76N2O14. Mole weight: 821.06. Catalog: APB425365657.
Roxithromycin EP Impurity I
Roxithromycin EP Impurity I. Uses: For analytical and research use. CAS No. 425365-66-8. Molecular formula: C45H84N2O17. Mole weight: 925.16. Catalog: APB425365668.
Roxithromycin EP Impurity J
Roxithromycin EP Impurity J. Uses: For analytical and research use. CAS No. 134834-12-1. Molecular formula: C40H73ClN2O14. Mole weight: 841.47. Catalog: APB134834121.
Roxithromycin EP impurity K
Roxithromycin EP impurity K. Uses: For analytical and research use. Molecular formula: C41H76N2O16. Mole weight: 853.06. Catalog: APB09435.
Roxithromycin Impurity 2
Roxithromycin Impurity 2. Uses: For analytical and research use. Molecular formula: C37H68N2O13. Mole weight: 748.95. Catalog: APB09436.
Roxithromycin Impurity 4
Roxithromycin Impurity 4. Uses: For analytical and research use. CAS No. 3970-21-6. Molecular formula: C4H9ClO2. Mole weight: 124.56. Catalog: APB3970216.
Roxithromycin Impurity 5
Roxithromycin Impurity 5. Uses: For analytical and research use. Molecular formula: C41H76N2O16. Mole weight: 853.06. Catalog: APB09437.
Roxithromycin Impurity C
An impurity found in the macrolide antibiotic, Clarithromycin. It exhibits antibacterial properties. Alternative Names: 9-Erythromycin 9-Oxime; 9-Erythromycin A Oxime; Erythromycin Oxime; Roxithromycin Impurity C; Clarithromycin EP Impurity J. Grades: >95%. CAS No. 13127-18-9. Molecular formula: C37H68N2O13. Mole weight: 748.94.
Roxithromycin Impurity F
A metabolite of the macrolide antibiotic, Roxithromycin. Alternative Names: (9E)-9-[O-[(2-Methoxyethoxy)methyl]oxime]-N-demethyl Erythromycin; (E)-N-Demethylroxithromycin; N-Demethylroxithromycin; RU 44981; Roxithromycin Impurity 6; Roxithromycin EP Impurity F. Grades: >95%. CAS No. 118267-18-8. Molecular formula: C40H74N2O15. Mole weight: 823.02.
ROX NHS ester, 6-isomer
ROX (rhodamine X aka R101) is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer. Grades: NMR 1H, HPLC-MS (80+%, balance mostly free carboxylic acid). CAS No. 117491-83-5. Molecular formula: C37H33N3O7. Mole weight: 631.67.
This ROX formulation is a passive reference dye for qPCR application. The use of this dye is recommended for the normalization of fluorescence intensity of qPCR reporter dyes, such as SYBR Green I or TaqMan probes. It also allows to correct for pipeting errors, and instrumental drift such as change of lamp intensity output over time. The dye contains 25 μM solution of 5-carboxy-ROX (rhodamine-X) reference dye in 10mM Tris-HCl (pH 8.6), 0.1mM EDTA, and 0.01% Tween®-20. Grades: NMR 1H, HPLC-MS (95%).
Royalisin
Royalisin is an antibacterial peptide isolated from Apis mellifera. It has activity against gram-positive bacteria. Alternative Names: Val-Thr-Cys-Asp-Leu-Leu-Ser-Phe-Lys-Gly-Gln-Val-Asn-Asp-Ser-Ala-Cys-Ala-Ala-Asn-Cys-Leu-Ser-Leu-Gly-Lys-Ala-Gly-Gly-His-Cys-Glu-Lys-Val-Gly-Cys-Ile-Cys-Arg-Lys-Thr-Ser-Phe-Lys-Asp-Leu-Trp-Asp-Lys-Arg-Phe. Mole weight: 5523.
Royal jelly
Royal jelly. Group: Biochemicals. Grades: Highly Purified. CAS No. 8031-67-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
Worldwide
Royal Jelly 6% Powder
Royal Jelly 6% Powder.
CA, FL & NJ
Royal Jelly acid
Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid. CAS No. 14113-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-N1363.
Royal Jelly Powder
Royal Jelly Powder.
Royal Jelly Powder
Royal Jelly Powder. Group: Others. Purity: 10-HDA 3%, 4%, 5%, 6%. Appearance: milk yellow powder. Source: Natural royal jelly. Royal Jelly Powder. Cat No: EXTC-126.
Rozanolixizumab
Rozanolixizumab (UCB7665), a humanized high-affinity anti-human neonatal Fc receptor (FcRn) monoclonal antibody (IgG4P), is used to the research of reducing pathogenic IgG in autoimmune and alloimmune diseases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB7665. CAS No. 1584645-37-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9979.
RP 001 hydrochloride
RP 001 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1306761-53-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
RP03707
RP03707 is a PROTAC degrader of KRASG12D. RP03707 forms a ternary complex with KRASG12D and the CRBN E3 ligase, promoting the ubiquitination and proteasomal degradation of KRASG12D. RP03707 inhibits the growth of KRASG12D-positive tumor cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3030493-05-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-176134.
RP-1
RP-1 is a synthetic antimicrobial peptide. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ala-Leu-Tyr-Lys-Lys-Phe-Lys-Lys-Lys-Leu-Leu-Lys-Ser-Leu-Lys-Arg-Leu. Grades: >95%. Molecular formula: C104H184N28O21. Mole weight: 2162.78.
RP101988
RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2990018-57-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136578.
RP-1551-1
RP-1551-1 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor potentially via reacting with amino groups on the alpha-receptor extracellular domain. Molecular formula: C25H29ClO6. Mole weight: 460.9.
RP-1551-2
RP-1551-2 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C24H31ClO5. Mole weight: 435.
RP-1551-3
RP-1551-3 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C25H27ClO5. Mole weight: 442.9.
RP-1551-4
RP-1551-4 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C25H29ClO6. Mole weight: 460.9.
RP-1551-5
RP-1551-5 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C25H33ClO5. Mole weight: 449.
RP-1551-6
RP-1551-6 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C25H29ClO6. Mole weight: 460.9.
RP-1551-7
RP-1551-7 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C19H23ClO4. Mole weight: 350.8.
RP-1551-8
RP-1551-8 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C26H31ClO6. Mole weight: 474.97.
RP-1551-9
RP-1551-9 is a compound in the class of azaphilone produced by Penicillium sp. SPC-21609. It inhibits the binding of PDGF AA to the extracellular domain of PDGF alpha-receptor. Molecular formula: C19H25ClO4. Mole weight: 352.85.
RP-1664
RP-1664 is a selective and orally active PLK4 inhibitor with an IC50 of 3 nM. RP-1664 demonstrates exquisite selectivity over related kinases, including AURKA/B and PLK1. RP-1664 disrupts centriole biogenesis in cancer cells and leads an accumulation of PLK4 and p21 protein. RP-1664 demonstrates increased sensitivity in TRIM37-high-expressing cells or tumors. RP-1664 exhibits anti-tumor activity in breast cancer and neuroblastoma research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2980682-00-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-172737.
RP-1776
RP-1776 is a cyclic peptide isolated from the culture broth of Streptomyces sp. KY11784. It selectively inhibits the binding of PDGF BB to the extracellular domain of the PDGF beta-receptor with an IC50 value of 11 ± 6 μmol/L. Alternative Names: RP 1776; RP1776. Molecular formula: C75H94N12O20. Mole weight: 1483.61.
RP-182
RP-182 is a synthetic immunomodulatory peptide that exerts anti-tumor effects by targeting the mannose receptor CD206 (Kd = 8 μM) on the surface of tumor-associated macrophages (TAMs). RP-182 induces a conformational switch of the CD206 receptor, which activates NF-κB signaling and phagocytosis in CD206high TAMs. RP-182 has dual function: activation of canonical NF-κB signaling, triggering TNFα secretion and autocrine activation of the TNF receptor 1 (TNFR1), leading to activation of caspase 8, apoptosis, and cell death. RP-182 is used in pancreatic cancer and melanoma research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1895883-60-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11108.
RP-21 / 1000: RPMI 1640
1lt Pack Size. Group: Diagnostic Raw Materials. Formula: N/A. Prepack ID 90029082-1lt. See USA prepack pricing.
Rp-2',3'-cAMPS
Rp-2',3'-cAMPS, a powerful stimulant of cAMP-dependent protein kinase (PKA), finds extensive application in biochemistry and biomedical research. By emulating the impact of endogenous cAMP, it effectively triggers PKA signaling pathways. The versatility of this compound allows for its frequent utilization in investigating the involvement of PKA in cellular signaling, gene expression, and the modulation of diverse diseases and disorders. Alternative Names: Adenosine- 2', 3'- cyclic monophosphorothioate, endo / Rp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 118275-99-3. Molecular formula: C10H11O5N5PS · Na. Mole weight: 367.3.
Rp-2'-AEC-cAMPS
Rp-2'-AEC-cAMPS is an analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 2'-AEC-cAMP. Alternative Names: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C13H18N7O6PS. Mole weight: 431.4.
Rp-2'-AEC-cAMPS-Agarose
Rp-2'-AEC-cAMPS-Agarose is the protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (2- Aminoethylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel.
Rp-2'-AHC-cAMPS
Rp-2'-AHC-cAMPS is an analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. It is also a PDE-resistant analogue of 2'-AHC-cAMP. Alternative Names: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O6PS. Mole weight: 487.5.
Rp-2'-AHC-cAMPS-Agarose
Rp-2'-AHC-cAMPS-Agarose is the PDE-resistant protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (6- Aminohexylcarbamoyl)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-2'-AHC-cGMPS
Rp-2'-AHC-cGMPS is a PDE-stable cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Alternative Names: 2'- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. Molecular formula: C17H26N7O7PS. Mole weight: 503.5.
Rp-2'-AHC-cGMPS-Agarose
Rp-2'-AHC-cGMPS-Agarose is the PDE-resistant PKG inhibitor Rp-cGMPS immobilized on agarose by an aminohexylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Alternative Names: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-2-Cl-cAMPS
Rp-2-Cl-cAMPS is an analogue of Rp-cAMPS, the protein kinase A inhibitor. The chlorine atom in position 2 of adenine nucleobase significantly increase the stability and lipophilicity. Alternative Names: 2- Chloroadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 124844-92-4. Molecular formula: C10H10ClN5O5PS · Na. Mole weight: 401.7.
Rp-2'-O-Me-CTP-α-S
Rp-2'-O-Me-CTP-α-S is a phosphorothioate analogue of CTP. Alternative Names: 2'-O-Methylcytidine-5'-O- (1-thiotriphosphate), Rp-isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143028-95-9. Molecular formula: C10H18N3O13P3S (free acid). Mole weight: 513.3 (free acid).
Rp-2'-O-Me-GTP-α-S
Rp-2'-O-Me-GTP-α-S is a phosphorothioate analogue of GTP. Alternative Names: 2'-O-Methylguanosine-5'-O-(1-thiotriphosphate), Rp-isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 143028-96-0. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid).
RP-3500
RP-3500 is an orally active, selective ATR kinase inhibitor (ATRi) with an IC50 of 1.00 nM in biochemical assays. RP-3500 shows 30-fold selectivity for ATR over mTOR (IC50 = 120 nM) and >2,000-fold selectivity over ATM, DNA-PK, and PI3Kα kinases. Antitumor activity. Alternative Names: ATR inhibitor 4. CAS No. 2417489-10-0. Molecular formula: C21H26N6O3. Mole weight: 410.47.
Rp-5,6-DCl-cBIMPS
Rp-5,6-DCl-cBIMPS is a phosphodiesterase-resistant regulator of cAMP-dependent protein kinase. Alternative Names: 5, 6- Dichlorobenzimidazole riboside- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 120912-55-2. Molecular formula: C12H10Cl2N2O5PS · Na. Mole weight: 419.2.
RP-6530
RP-6530, a purine derivative, has been found to be a PI3Kδ/γ inhibitor that could exhibit cytotoxicity in some lymphoma primary cells so that is significant in antineoplastic researches. It has already completed a Phase I trial for Haematological malignancies. Uses: Phosphoinositide-3 kinase inhibitors. Alternative Names: RP-6530; RP6530; RP 6530; Tenalisib; (S)-2-(1-((7H-purin-6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one. Grades: 98%. CAS No. 1639417-53-0. Molecular formula: C23H18FN5O2. Mole weight: 415.43.
RP-66453
RP-66453 is a secondary peptide metabolite produced by Streptomyces sp. A 9738. It can selectively bind to neurotensin receptor. Alternative Names: RP 66453; RP66453. Molecular formula: C33H36N4O8. Mole weight: 616.7.
RP-6685
RP-6685. CAS No. 2832047-80-8.
RP-6685
RP-6685 is a potent, selective and orally active DNA polymerase theta (Polθ) inhibitor with an IC50 value of 5.8 nM (PicoGreen assay). RP-6685 shows antitumor efficacy in mouse tumor xenograft model[1]. RP-6685 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832047-80-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-151462.
RP 67580
RP 67580. Group: Biochemicals. Grades: Purified. CAS No. 135911-02-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Rp-6-Cl-cPuMPS
Rp-6-Cl-cPuMPS is a PDE-resistant modulator of protein kinase A that can be modified in position 6. Alternative Names: 6- Chloropurine riboside- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 129693-15-8. Molecular formula: C10H9ClN4O5PS · Na. Mole weight: 386.7.
Rp-6-Phe-cAMPS
Rp-6-Phe-cAMPS is a potent biomedical compound, showcasing its applications in targeting and regulating the intricate network of cyclic adenosine monophosphate (cAMP) pathways. This groundbreaking product exhibits immense potential in ameliorating dysregulated cAMP signaling, aiding in research on afflictions spanning cancer, metabolic disorders and cardiovascular diseases. CAS No. 169335-91-5. Molecular formula: C16H15N5O5PS · Na. Mole weight: 443.4.
Rp 71955
Rp 71955 is an antibacterial peptide isolated from Streptomyces sp. It has activity against viruses. Alternative Names: aborycin; Cys-Leu-Gly-Ile-Gly-Ser-Cys-Asn-Asp-Phe-Ala-Gly-Cys-Gly-Tyr-Ala-Val-Val-Cys-Phe-Trp. Molecular formula: C97H131N23O26S4. Mole weight: 2163.5.
RP-71955
RP-71955 is a tricyclic 21 amino acid peptide produced by Streptomyces sp. SP9400. It is active against HIV-1. Alternative Names: RP 71955; RP71955. CAS No. 152835-17-1. Molecular formula: C97H131N23O26S4. Mole weight: 2163.5.
RP-832c
RP-832c is a synthetic analogue of host defense peptides (HDP), targeting the mannose receptor CD206 on the surface of M2 polarized macrophages (Kd = 3.5 μM). RP-832c binding to CD206 induces a significant conformational change in the receptor, activating signaling pathways that lead to rapid apoptosis and repolarization of CD206-positive M2 macrophages to an M1 phenotype. RP-832c treatment significantly reduces CD206 gene expression in M2 macrophages while transiently increasing expression of TNF-α, a marker for M1 macrophages. RP-832c is used for the studies of T-cell lymphoma (CTCL) and idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375823-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P11107.
Rp-8-AEA-cAMPS
Rp-8-AEA-cAMPS is a phosphodiesterase-resistant ligand for affinity chromatography of cAMP and cGMP binding proteins. It is often modified with fluorophores and other markers. Alternative Names: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-78-5. Molecular formula: C12H18N7O5PS. Mole weight: 403.4.
Rp-8-AEA-cAMPS-Agarose
Rp-8-AEA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminoethylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, immobilized on agarose gel.
Rp-8-AET-cGMPS
Rp-8-AET-cGMPS is a ligand in affinity chromatography and can be modified with fluorophores or other markers. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 221904-88-7. Molecular formula: C12H17N6O6PS2. Mole weight: 436.4.
Rp-8-AET-cGMPS-Agarose
Rp-8-AET-cGMPS-Agarose is the metabolically stable protein kinase G inhibitor Rp-cGMPS immobilized on agarose by an aminoethylthio spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Alternative Names: 8- (2- Aminoethylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-8-AHA-cAMPS
Rp-8-AHA-cAMPS is a PDE-resistant analogue of Rp-cAMPS, the PKA inhibitor, which is used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer. Grades: ≥ 98% by HPLC. CAS No. 214272-02-3. Molecular formula: C16H26N7O5PS. Mole weight: 459.5.
Rp-8-AHA-cAMPS-Agarose
Rp-8-AHA-cAMPS-Agarose is the metabolically stable protein kinase A inhibitor Rp-cAMPS immobilized on agarose by an aminohexylamino spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinase A (presumably as its holoenzyme), phosphodiesterases and others. Alternative Names: 8- (6- Aminohexylamino)adenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer; immobilized on agarose gel.
Rp-8-Br-2'-O-MB-cAMPS
Rp-8-Br-2'-O-MB-cAMPS is a precursor of Rp-8-Br-cAMPS, the protein kinase A inhibitor. Rp-8-Br-cAMPS and butyrate are released after the metabolism of Rp-8-Br-2'-O-MB-cAMPS by esterases. Alternative Names: 8- Bromo- 2'- O- monobutyryladenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 788807-32-9. Molecular formula: C14H16BrN5O6PS · Na. Mole weight: 516.2.
Rp-8-Br-cAMPS
Rp-8-Br-cAMPS is an analogue of the cAMP with a preference for type I of protein kinase A. Compared to Rp-cAMPS, it has more lipophilic and membrane-permeant properties. Rp-8-Br-cAMPS effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Alternative Names: 8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 129735-00-8. Molecular formula: C10H10BrN5O5PS · Na. Mole weight: 446.2.
Rp-8-Br-cAMPS sodium
Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. Rp-8-Br-cAMPS sodium occupies cAMP binding sites on PKA type I regulatory subunits, thereby preventing PKA dissociation and activation. Rp-8-Br-cAMPS sodium can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS sodium also inhibits insulin secretion[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 925456-59-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-137640C.
Rp-8-Br-cGMPS
Rp-8-Br-cGMPS is an inhibitor of protein kinase G I α and I ß. It effects against mammalian cyclic nucleotide- dependent phosphodiesterases. Compared to cGMP or Rp-cGMPS, it has more lipophilic and membrane-permeant properties. Alternative Names: 8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 150418-07-8. Molecular formula: C10H10BrN5O6PS · Na. Mole weight: 462.2.
Rp-8-Br-cGMPS sodium
Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca2+ reduction by activating Ca2+-ATPase and subsequently removing Ca2+ from the cell[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Rp-8-bromo-Cyclic GMPS sodium. CAS No. 208445-06-1. Pack Sizes: 1 mg. Product ID: HY-135110.
Rp-8-Bromo-β-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt
Rp-8-Bromo-β-phenyl-1,N2-ethenoguanosine 3,5-cyclic monophosphorothioate sodium salt. Uses: For analytical and research use. CAS No. 185246-32-6. Mole weight: 562.27. Catalog: AP185246326.