A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
SB505124 is a selective inhibitor of transforming growth factor-β type I receptor (ALK5, ALK4 and ALK7) with potential anticancer activity. SB505124 selectively inhibits signaling from TGF-β and activin but does not inhibit other ALK family members. Synonyms: SB-505124; 2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl)-6-methylpyridine. Grades: >98%. CAS No. 694433-59-5. Molecular formula: C20H21N3O2. Mole weight: 335.407.
SB 505124
SB 505124. Group: Biochemicals. Grades: Purified. CAS No. 694433-59-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptor ALK5 and as well as being a selective inhibitor of ALK4 but with less potency. SB-505124 blocks TGF-β-induced apoptosis of FaO cells and NRP 154 cells in a concentration-dependent manner. SB-505124 has been shown to suppress the migration and invasion of breast cancer MCF-7-M5 cells. Synonyms: SB 505124 hydrochloride; SB505124 hydrochloride; SB505124 HCl; SB 505124 HCl; SB-505124 HCl. Grades: >98%. CAS No. 356559-13-2. Molecular formula: C20H22ClN3O2. Mole weight: 371.86.
SB525334
SB-525334 is a potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM). It is ~4-fold less effective against ALK4 and inactive against ALK2, ALK3, and ALK6. Synonyms: SB525334; SB-525334; SB 525334. Grades: >98%. CAS No. 356559-20-1. Molecular formula: C21H21N5. Mole weight: 343.42494.
SB 525334 (SB-525334, 6-(2-(tert-Butyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)quinoxaline). Group: Biochemicals. Grades: Highly Purified. CAS No. 356559-20-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C21H21N5, Molecular Weight: 343.4. US Biological Life Sciences.
Worldwide
SB-590885
SB-590885 is a novel triarylimidazole that selectively inhibits Raf kinases. SB-590885 stabilizes the oncogenic B-Raf kinase domain in an active configuration. Malignant cells expressing oncogenic B-Raf show selective inhibition of mitogen-activated protein kinase activation, proliferation, transformation, and tumorigenicity when exposed to SB-590885, whereas other cancer cell lines and normal cells display variable sensitivities or resistance to similar treatment. Synonyms: SB590885; SB 590885. Grades: 0.98. CAS No. 405554-55-4. Molecular formula: C27H27N5O2. Mole weight: 453.54.
SB-590885
SB-590885 is a potent B-Raf inhibitor with a K i of 0.16 nM, and has 11-fold greater selectivity for B-Raf over c-Raf, without inhibition to other human kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 405554-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10966.
SB 611812
SB 611812 is a urotensin-II (UT) antagonist that inhibits urotensin-II-induced proliferation of neonatal cardiac fibroblasts. SB 611812 attenuates cardiac dysfunction in a rat model of coronary artery ligation, and decreases cardiomyocyte hypertrophy, ventricular dilatation and cardiac remodeling. Synonyms: SB-611812; SB 611812; SB611812. 2,6-Dichloro-N-[4-chloro-3-[2-(dimethylamino)ethoxy]phenyl]-4-(trifluoromethyl)benzenesulfonamide. Grades: ≥99% by HPLC. CAS No. 345892-71-9. Molecular formula: C17H16Cl3F3N2O3S. Mole weight: 491.74.
SB 612111
SB 612111 hydrochloride is a selective nociceptin/orphanin FQ (NOP) receptor antagonist (Ki value 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). It modulates the pronociceptive action of nociceptin in an acute pain model and enhances morphine action in morphine-tolerant animals and inhibits hyperalgesia in an inflammatory pain model. Synonyms: SB 612111 hydrochloride; SB612111 hydrochloride; SB-612111 hydrochloride; (5S,7S)-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-1-methyl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-ol hydrochloride. Grades: 99%. CAS No. 371980-98-2. Molecular formula: C24H29Cl2NO. Mole weight: 418.4.
SB 612111 hydrochloride
SB 612111 hydrochloride. CAS No: 371980-98-2
Sarchem Laboratories New Jersey NJ
SB 612111 hydrochloride
SB 612111 hydrochloride is a selective NOP receptor antagonist (Ki = 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors, respectively). SB 612111 exhibits antagonist activity at the pronociceptive action of nociceptin in an acute pain model. SB 612111 potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model. Synonyms: SB 612111 hydrochloride; SB612111 hydrochloride; SB-612111 hydrochloride; 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol hydrochloride. Grades: ≥97% by HPLC. CAS No. 371980-94-8. Molecular formula: C24H29Cl2NO.HCl. Mole weight: 454.86.
SB-649868
SB-649868 is a potent and selective orally active orexin ( OX ) 1 and OX 2 receptor antagonist ( pK i =9.4 and 9.5 at the OX 1 and OX 2 receptor, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK649868. CAS No. 380899-24-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10806.
SB-649868
SB-649868 is a novel, orally active dual orexin receptor antagonist of orexin(OX)1 and OX2 receptor (pKi=9.4 and 9.5 at the OX1 and OX2 receptor, respectively), potentially for the treatment of insomnia and sleep disorder. Synonyms: N-[[(2S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide; (14C)SB 649868; (14C)SB-649868; (14C)SB649868; N-((1-((5-(4-fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide; SB 649868; SB-649868; SB649868; GSK-649868; GSK-649868; GSK649868. CAS No. 380899-24-1. Molecular formula: C26H24FN3O3S. Mole weight: 477.55.
SB 657510
SB 657510 is a selective urotensin-II (UT) receptor/GRP14 antagonist (Ki = 61, 17, 30, 65 and 56 nM at human, monkey, cat, rat and mouse receptors, respectively). SB 657510 was also shown to inhibit U-II-induced intracellular Ca2+ mobilization (IC50 = 180 nM) and antagonize the contractile action of U-II in isolated mammalian arteries and aortae (EC50 = 50 - 189 nM). Synonyms: SB 657510; SB657510; SB-657510; 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 474960-44-6. Molecular formula: C19H22BrClN2O5S. Mole weight: 505.81.
SB-674042
SB-674042 is potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM), by binding with high affinity to OX1R and mediates intracellular calcium flux in OX1R-expressing cells. Uses: Potent and selective non-peptide orexin ox1 receptor antagonist. Synonyms: SB 674042; SB-674042; SB674042; [5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone. Grades: ≥98%. CAS No. 483313-22-0. Molecular formula: C24H21FN4O2S. Mole weight: 448.51.
SB-674042
SB-674042 is a potent and selective non-peptide orexin OX 1 receptor antagonist (K d =5.03 nM), exhibits 100-fold selectivity for OX 1 over OX 2 receptors with IC 50 values of 3.76 nM and 531 nM, respectively [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 483313-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10898.
SB-699551
SB-699551 is a potent and selective 5-HT5A antagonist with a K i value of 5.1 μM. SB-699551 increases the phosphorylation levels of CREB and ATF1 , and decreases the phosphorylation levels of AKT , PRAS40 , P70S6K , FOXO1 , and S6RP. SB-699551 improves drug-induced cognitive deficits. SB-699551 improves social withdrawal and forgetfulness. SB-699551 inhibits breast cancer. Uses: Scientific research. Group: Signaling pathways. CAS No. 864741-95-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-103100.
SB 699551 dihydrochloride
SB 699551 is a selective 5-HT5A receptor antagonist (pKi = 8.3, < 6.0, < 6.0, < 6.0, < 5.5 and < 5.5 for 5-ht5a, 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors, respectively). Synonyms: SB 699551 dihydrochloride; SB699551 dihydrochloride; SB-699551 dihydrochloride; N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide dihydrochloride. Grades: ≥99% by HPLC. CAS No. 864741-95-7. Molecular formula: C34H45N3O.2HCl. Mole weight: 584.66.
A selective, brain penetrant, 5-HT5A receptor antagonis (pKi = 8.2). Competitively antagonised 5-HT-stimulated [35S]GTP-gamma-S binding to membranes from human embryonic kidney (HEK293) cells transiently expressing the guinea pig 5-HT5A receptor (pA2 8.1 ± 0.1) and displayed 100-fold selectivity versus the serotonin transporter and those 5-HT receptor subtypes (5-HT1A/B/D, 5-HT2A/C and 5-5-HT7). Group: Biochemicals. Grades: Highly Purified. CAS No. 791789-61-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O·2HCl. US Biological Life Sciences.
Worldwide
SB705498
SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Synonyms: SB-705498; SB 705498; SB705498. Grades: >98%. CAS No. 501951-42-4. Molecular formula: C17H16BrF3N4O. Mole weight: 429.23.
SB-705498
SB-705498. Group: Biochemicals. Grades: Highly Purified. CAS No. 501951-42-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
SB 706375
SB 706375 is a high affinity and non-peptide antagonist of the mammalian urotensin-II (UT) receptor displaying ≥100-fold selectivity for the human UT receptor over 86 different receptors, ion channels, enzymes, transporters and nuclear hormones. SB 706375 also inhibits binding of radiolabeled urotensin to endogenous human UT receptors (Ki = 5.4 nM in a whole-cell binding assay). Synonyms: SB-706375; SB 706375; SB706375. 2-Bromo-4, 5-dimethoxy-N-[3-[[ (3R) -1-methyl-3-pyrrolidinyl]oxy]-4- (trifluoromethyl) phenyl]benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 733734-61-7. Molecular formula: C20H22BrF3N2O5S. Mole weight: 539.36.
SB 706504
SB 706504 is a p38 MAPK inhibitor. SB 706504 inhibits LPS-induced transcription of a range of chemokines and cytokines in chronic obstructive pulmonary disease (COPD) monocyte derived macrophages (MDMs), and it also suppresses LPS-induced protein expression of IL-6, IL-10, TNFα and γ-inducible protein 10 in COPD MDMs. Synonyms: SB 706504; SB706504; SB-706504; N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine; 1-cyano-2-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine. Grades: ≥98% by HPLC. CAS No. 911110-38-8. Molecular formula: C24H19F3N8O. Mole weight: 492.46.
SB742457
SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease. Synonyms: SB742457; SB 742457; SB-742457; RVT-101; RVT 101; RVT101. intepirdine. GSK 742457; GSK742457; GSK-742457. Grades: >98%. CAS No. 607742-69-8. Molecular formula: C19H19N3O2S. Mole weight: 353.44.
SB 742457 hydrochloride
SB 742457 hydrochloride is a selective 5-HT6 antagonist with >100-fold selectivity over other receptors. It is a potential agent added to stabilize donepezil treatment in subjects with mild-to-moderate Alzheimer's disease. Uses: Potential treatment of alzheimer's disease in combination with donepezil. Synonyms: GSK-742457 hydrochloride; RVT-101 hydrochloride; SB-742457 hydrochloride; GSK 742457 hydrochloride; RVT 101 hydrochloride; SB 742457 hydrochloride; GSK742457 hydrochloride; RVT101 hydrochloride; SB742457 hydrochloride; Intepirdine hydrochloride; 3-Phenylsulfonyl-8-piperazin-1-yl-quinoline hydrochloride. Grades: 99%. CAS No. 607742-55-2. Molecular formula: C19H19N3O2S.HCl. Mole weight: 389.9.
SB-743921 HCl
SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis. Synonyms: SB-743921; SB 743921; SB743921. Grades: >98%. CAS No. 940929-33-9. Molecular formula: C31H34Cl2N2O3. Mole weight: 553.524.
SB-743921 hydrochloride
SB-743921 hydrochloride is a potent inhibitor of the mitotic kinesin KSP (Eg5) , with a K i of 0.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 940929-33-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12069.
SB 747651A dihydrochloride
SB 747651A dihydrochloride is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay). SB 747651A has been shown to inhibit MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells, and suppress IL-10 production in macrophages. Synonyms: SB747651A dihydrochloride; SB 747651A dihydrochloride; SB-747651A dihydrochloride; 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-1H-imidazo[4,5-c]pyridine-7-methanamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1781882-72-1. Molecular formula: C16H22N8O.2HCl. Mole weight: 415.32.
SB 747651A tetrahydrochloride
SB 747651A tetrahydrochloride is a potent and ATP-competitive inhibitor of mitogen- and stress-activated kinase 1 (MSK1) with an IC50 value of 11 nM. Synonyms: SB 747651A tetrahydrochloride; SB747651A tetrahydrochloride; SB-747651A tetrahydrochloride; 4-[1-ethyl-7-[(piperidin-4-ylamino)methyl]imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine tetrahydrochloride. Grades: 98%. CAS No. 2108968-31-4. Molecular formula: C16H22N8O.4HCl. Mole weight: 488.24.
SB756050
SB756050 is a selective TGR5 agonist currently undergone testing in a phase 1 clinical trials study in the treatment of type 2 diabetes. Synonyms: 1,4-bis[(3,4-dimethoxyphenyl)sulfonyl]-1,4-diazepane; SB756050; F1018-1711; 1,4-bis((3,4-dimethoxyphenyl)sulfonyl)-1,4-diazepane; SB-756050; SB 756050; SB756050. CAS No. 447410-57-3. Molecular formula: C21H28N2O8S2. Mole weight: 500.59.
SB 772077B dihydrochloride
SB 772077B dihydrochloride is a potent Rho-kinase (ROCK) inhibitor (IC50 ~ 5.6 nM at recombinant human ROCK1 and 2) exhibiting potent vasodilator activity. SB 772077B decreases pulmonary and systemic arterial blood pressure levels and increases cardiac output. Synonyms: SB-7720770 2HCl; SB 7720770 2HCl; SB7720770 2HCl; SB-7720770 dihydrochloride; SB 7720770 dihydrochloride; SB7720770 dihydrochloride; (3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 607373-46-6. Molecular formula: C15H18N8O2.2HCl. Mole weight: 415.28.
SBA-15
SBA-15. Group: Sba-15. CAS No. 12173-28-3. Pack Sizes: 1 kg.
SBA-15 Molecular Sieve
Transparent to gray, odorless powder. Irritating to the skin and eyes on contact. Inhalation will cause irritation in the respiratory tract. [Note: Amorphous silica is the non-crystalline form of SiO2.];PelletsLargeCrystals, OtherSolid, Liquid;DryPowder; Liquid;DryPowder; OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals;DryPowder; OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, OtherSolid, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, PelletsLargeCrystals, OtherSolid; DryPowder, PelletsLargeCrystals, WetSolid; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid; WetSolid, Liquid;PelletsLargeCrystals;White, fluffy powder or granules. Hygroscopic;Solid;FINE WHITE POWDER.;COLOURLESS OR WHITE CRYSTALS.;COLOURLESS WHITE CRYSTALS.;COLOURLESS OR WHITE CRYSTALS.;Solid;Transparent to gray, odorless powder. [Note: Amorphous silica is the non-crystalline form of SiO2.]. Group: Molecular sieve. CAS No. 7631-86-9. Product ID: dioxosilane. Molecular formula: 60.084g/mol. Mole weight: (SiO2)n; SiO2; SiO2; SiO2; SiO2; SiO2; O2Si. O=[Si]=O. InChI=1S/O2Si/c1-3-2. VYPSYNLAJGMNEJ-UHFFFAOYSA-N.
S(-)-Baclofen Hydrochloride
S(-)-Baclofen Hydrochloride is the salt of Baclofen, which is a specific GABA-B receptor agonist and muscle relaxant (skeletal). It is primarily used to treat spasticity. Synonyms: l-Baclofenhydrochloride; (S)-4-Amino-3-(4-chlorophenyl)butyric Acid Hydrochloride; (-)-Baclofen Hydrochloride; β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride; (S)-β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride; (βS)-β-(Aminomethyl)-4-chloro-benzenepropanoic Acid Hydrochloride. CAS No. 63701-56-4. Molecular formula: C10H13Cl2NO2. Mole weight: 250.12.
sBADA
sBADA is a potent green fluorescent dye. sBADA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA is used to label peptidoglycans in bacterial cell walls in situ. (λ ex =490 nm, λ em =510 nm) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2376838-11-6. Pack Sizes: 1 mg. Product ID: HY-D1690A.
S(-)-BAY K 8644
S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the enantiomer of (±)-Bay K 8644. It increased whole-cell Ca2+ currents in A7r5 smooth muscle cells but effectively blocked further stimulatio. It enhanced transcoronary exchange more markedly than (+/-)-Bay W 5035 or (+/-)-Bay T 5006, reflecting the differences in coronary constrictor activity. It demonstrates vasoconstrictive and positive inotropic effects in vivo as well as behavioral effects, including deficits to motor function. It can enable reprogramming of mouse embryonic fibroblasts after transduction with Oct4/Klf when combined with BIX01294. Uses: S(-)-bay k 8644 has positive inotropic, vasoconstrictive and behavioral effects. Synonyms: Methyl (4S)-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate;Bay-K-8644 (S)-(-)-;(S)-(-)-Bay-K-8644;(4S)-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethyl)phenyl)-3-pyridinecarboxylicacidmethylester;S-(-)-1,4-dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid methyl ester;[4S,(-)]-1,4-Dihydro-2,6-dimethyl-5-nitro-4-(2-trifluoromethylphenyl)pyridine-3-carboxylic acid methyl ester. Grades: >99 %. CAS No. 98625-26-4. Molecular formula: C16H15F3N2O4. Mole weight: 356.30.
Sbc-1107326
SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). Study shows that it can lower cholesterol levels in mice. Synonyms: Sbc 1107326; Sbc1107326; N-[4-(2-Phenyl-4-p-tolyl-piperazine-1-carbonyl)-phenyl]-acetamide. Grades: ≥98%. CAS No. 1629166-02-4. Molecular formula: C26H27N3O2. Mole weight: 413.51.
SBC-115076
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist. Synonyms: SBC-115076; SBC 115076; SBC115076. Grades: 98%. CAS No. 489415-96-5. Molecular formula: C31H33N3O5. Mole weight: 527.62.
SBD-1
SBD-1 is an antibacterial peptide isolated from Ov is aries. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Beta-defensin 1; BD-1; Asn-Arg-Leu-Ser-Cys-His-Arg-Asn-Lys-Gly-Val-Cys-Val-Pro-Ser-Arg-Cys-Pro-Arg-His-Met-Arg-Gln-Ile-Gly-Thr-Cys-Arg-Gly-Pro-Pro-Val-Lys-Cys-Cys-Arg-Lys-Lys. Molecular formula: C195H342N78O50S7. Mole weight: 4803.77.
SBE13
SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. Its IC50 value is 0.2 nM. It does not effect the activity of Plk2, Plk3 and Aurora A kinases. It may be used in cell signaling studies. Uses: Sbe13 may be used in cell signaling studies. Synonyms: SBE13; SBE 13; SBE-13; STK510569;N-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methyl]-2-(3,4-dimethoxyphenyl)ethanamine. Grades: >98%. CAS No. 775294-82-1. Molecular formula: C24H27ClN2O4. Mole weight: 442.94.
SBE-13 HCl
SBE-13 is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μ M for PLK1, PLK3 and PLK2 respectively). Group: Inhibitors. Alternative Names: SBE13; SBE 13; SBE13; SBE-13 HCl. CAS No. 1052532-15-6. Molecular formula: C24H27ClN2O4. Mole weight: 442.94. Appearance: White solid powder. Purity: >98%. IUPACName: N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride. Canonical SMILES: COC1=CC=C (CCNCC2=CC=C (OCC3=CC=C (Cl)N=C3)C (OC)=C2)C=C1OC. [H]Cl. Catalog: ACM1052532156.
SBE-13 HCl
SBE13 is a cell-permeable highly potent polo-like kinase (Plk1) inhibitor that targets the inactive conformation of the kinase. SBE13 does not effect the activity of Plk2, Plk3, Aurora A kinases. Synonyms: SBE 13 HCl; SBE13 HCl. Grades: 0.98. CAS No. 1052532-15-6. Molecular formula: C24H28Cl2N2O4. Mole weight: 479.398.
SBE 13 hydrochloride
SBE 13 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1052532-15-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
SBE-β-CD, also called as Sulfobutylether beta-cyclodextrin sodium, is a β-Cyclodextrin derivative with sulfobutyl ether groups and sodium ions substituted designed to optimize the drug properties. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation. Synonyms: SBE4-b-CyD; SBECD; Betadex Sulfobutyl Ether Sodium; Sulfobutyl Ether Beta-Cyclodextrin; Sulfobutyl Ether-Beta-Cyclodextrin; Sodium Sulphobutylether-Beta-Cyclodextrin. Grades: 95%. CAS No. 182410-00-0. Molecular formula: C70H119Na7O56S7. Mole weight: 2242.05.
S-Benzyl-aziridine
S-Benzyl-aziridine. Group: Biochemicals. Grades: Highly Purified. CAS No. 73058-30-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C9H11N. US Biological Life Sciences.