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| Product | Description | |
|---|---|---|
| S-Carbonyl Reductase (Crude Enzyme) | This product with the indicated enzyme activity was briefly purified from engineered E. coli, and can be used for NADH regeneration in biotechnology. Applications: Synthesis. Group: Enzymes. Synonyms: ADH; ADH1; ADH2; ADHTt; carbonyl reductase (NADH, specific for (S)-configuration of alcohol); short-chain NAD(H)-dependent alcohol dehydrogenase. Enzyme Commission Number: EC 1.1.1.B4. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. ADH; ADH1; ADH2; ADHTt; carbonyl reductase (NADH, specific for (S)-configuration of alcohol); short-chain NAD(H)-dependent alcohol dehydrogenase. Pack: 100ml. Cat No: NATE-1789. |  |
| S-carboxymethylcysteine synthase | A pyridoxal-phosphate protein. Group: Enzymes. Synonyms: S-carboxymethyl-L-cysteine synthase. Enzyme Commission Number: EC 4.5.1.5. CAS No. 124671-39-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5347; S-carboxymethylcysteine synthase; EC 4.5.1.5; 124671-39-2; S-carboxymethyl-L-cysteine synthase. Cat No: EXWM-5347. | |
| S-(Carboxymethyl)-L-cysteine | S-(Carboxymethyl)-L-cysteine. Group: Biochemicals. Alternative Names: (2R) -2-Amino-3-[ (carboxymethyl) thio]propionic acid; (R) -S- (Carboxymethyl) cysteine; (L) -2-Amino-3- (carboxymethylthio) propionic acid. Grades: Highly Purified. CAS No. 638-23-3. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C5H9NO4S. US Biological Life Sciences. |  Worldwide |
| S)-Carboxymethyl-L-cysteine | 100g Pack Size. Group: Amino Acids, Building Blocks. Formula: C5H9NO4S. CAS No. 638-23-3. Prepack ID 21213990-100g. Molecular Weight 179.19. See USA prepack pricing. |  |
| S-Carboxymethyl-L-cysteine 99+% | S-Carboxymethyl-L-cysteine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| Scarlet 808 | Scarlet 808. Group: Biochemicals. CAS No. 3789-75-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Scarlet acid | Scarlet acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 134-47-4. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| SCD1 Antibody [H13N22] | SCD1. Group: Antibodies. Alternative Names: FADS5; SCD1; SCDOS; SCD; Stearoyl-CoA desaturase; hSCD1; Acyl-CoA desaturase; Delta(9)-desaturase; Fatty acid desaturase; Delta-9 desaturase. CAS No. Pack Sizes: 20uL. Product ID: F3395. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| SCD1 inhibitor-4 | SCD1 inhibitor-4 is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1295541-87-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141525. |  |
| Sceliphrolactam | Sceliphrolactam is a polyene antibiotic also known to have antifungal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1267888-95-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H35NO6, Molecular Weight: 481.58. US Biological Life Sciences. | Worldwide |
| Scensidin | Scensidin is a new depsidone isolated from the lichen Buellia canescens. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 2,7-dichloro-3,8-dimethoxy-1,6-dimethyl-; 2,8-dichloro-3,9-dimethoxy-1,7-dimethylbenzo[b][1,4]benzodioxepin-6-one. CAS No. 86190-23-0. Molecular formula: C17H14Cl2O5. Mole weight: 369.20. |  |
| Scentenal® | Scentenal®. CAS No. 86803-90-9. Kosher: Y. VIGON Item # 502840. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, ocean carboxaldehyde. |  America & Internationally |
| SCH 202676 hydrobromide | SCH 202676 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 265980-25-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-202676 hydrobromide | SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). SCH-202676 hydrobromide has antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 265980-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110012. | |
| Sch-20561 | Sch-20561 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Alternative Names: Sch 20561. Molecular formula: C57H86N12O16. Mole weight: 1195.4. | |
| Sch-20562 | Sch-20562 is a cyclic dehydropeptide lactone produced by Aeromonas sp. W-10 NRRL B11053. It is a major component of W-10 antifungal antibiotic. Alternative Names: Sch 20562. Molecular formula: C63H96N12O21. Mole weight: 1357.5. | |
| Sch 218157 | Sch 218157 is a cyclodepsipeptide isolated from an unidentified fungus MYCO-2833. It selectively binds to NK2 receptor with IC50 of 68 nmol/L. Alternative Names: Sch-218157. Molecular formula: C57H89N11O13. Mole weight: 1136.4. | |
| SCH 221510 | SCH 221510. Group: Biochemicals. Grades: Purified. CAS No. 322473-89-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 221510 | SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC50 of 12 nM and Ki of 0.3 nM. SCH 221510 shows an anxiolytic-like effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 322473-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107722. | |
| SCH 23390 hydrochloride | SCH 23390 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 125941-87-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-23390 hydrochloride | SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R-(+)-SCH-23390 hydrochloride. CAS No. 125941-87-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19545A. | |
| SCH 23390 Hydrochloride (Dopamine Receptor D1/D5 Antagonist, SCH 23390, (R)-(+)-7-Chloro-8-hydroxy-3-methyl--1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride, SCH23390, SCH-23390) | A highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3nM and 9.3nM respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 125941-87-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClNO HCl. US Biological Life Sciences. | Worldwide |
| SCH 28080 | SCH 28080. Group: Biochemicals. Grades: Purified. CAS No. 76081-98-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sch-31828 | Sch-31828 is a novel antibiotic from a Microbispora sp. SCC 1438. It is commonly used as methyl ether form. Alternative Names: Sch 31828; Antibiotic EV22; EV 22. CAS No. 115216-83-6. Molecular formula: C17H18O6. Mole weight: 318.32. | |
| SCH 336 | SCH 336 is a potent, selective, inverse and orally active CB2 agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SCH-225336. CAS No. 447459-51-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121852. | |
| Sch-37137 | Sch-37137 is a dipeptide antibiotic produced by Micromonospora sp. SCC 1792. It was weakly active against species of Candida and dermatophytes (mean MICs greater than or equal to 128 mg/ml) in Sabouraud dextrose, yeast-nitrogen and modified Eagles minimum essential media; however activity against Candida sp. (mean MICs greater than or equal to 12 mg/ml) and dermatophytes (mean MICs greater than or equal to 0.8 mg/ml) significantly improved in MA medium. Alternative Names: Sch 37137; N-L-Alanyl-3-(((3-(aminocarbonyl)oxiranyl)carbonyl)amino)-L-alanine. Grades: 95%. CAS No. 113737-67-0. Molecular formula: C10H16N4O6. Mole weight: 288.26. | |
| Sch-38516 | Sch-38516 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 0.91 μg/mL. Alternative Names: Sch 38516. CAS No. 128563-23-5. Molecular formula: C24H46N2O5. Mole weight: 442.6. | |
| Sch-38518 | Sch-38518 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 1.81 μg/mL. Alternative Names: Sch 38518. CAS No. 135559-94-3. Molecular formula: C25H48N2O5. Mole weight: 456.7. | |
| Sch-38519 | Sch-38519 is an isochromanequinone structurally related to lactoquinomycin. It is isolated from Thermomonospora sp. SCC 1793. It inhibits thrombin-induced aggregation of human platelets and is active against gram-positive and gram-negative bacteria. Alternative Names: Sch 38519; Antibiotic Sch 38519. Grades: >95% by HPLC. CAS No. 114970-20-6. Molecular formula: C24H25NO8. Mole weight: 455.4. | |
| SCH 39166 hydrobromide | SCH 39166 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1227675-51-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sch-39185 | Sch-39185 is a macrolactam antibiotic produced by Actinomadura sp. SCC 1776 and SCC 1777. It exhibits activity against Candida sp. with MIC of 2 μg/mL. Alternative Names: Sch 39185. CAS No. 135559-95-4. Molecular formula: C25H48N2O5. Mole weight: 456.7. | |
| Sch 40832 | Sch 40832 is an antibiotic produced by Micromonospora carbonacea var africana. It exhibits activity against gram-positive bacteria with MIC of 0.1-1.0 μg/mL. Alternative Names: Antibiotic Sch 40832; Sch-40832. Molecular formula: C84H104N18O26S5. Mole weight: 1942.2. | |
| Sch 420789 | Sch 420789 is a phospholipase D inhibitor produced by an unidentified fungus SCF 0953. Alternative Names: Sch-420789. Molecular formula: C27H36O6. Mole weight: 456.6. | |
| Sch 42137 | Sch 42137 is an antifungal antibiotic isolated from Actinoplanes sp. It exhibited MIC values less than 0.125 μg/mL against yeasts and dermatophytes. Alternative Names: Antibiotic Sch 42137; Sch-42137. CAS No. 142383-44-6. Molecular formula: C29H27NO10. Mole weight: 549.5. | |
| SCH442416 | SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 316173-57-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103169. | |
| SCH 442416 | SCH 442416. Group: Biochemicals. Grades: Purified. CAS No. 316173-57-6. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sch 466457 | Sch 466457 is a peptide active against Candida, dermatophytes and Aspergillus with MIC of 8.9, 20 and 16 microg/mL. Alternative Names: Sch-466457. Molecular formula: C80H140N20O20. Mole weight: 1702.08. | |
| Sch 47554 | Sch 47554 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Alternative Names: Antibiotic Sch 47554; Sch-47554. CAS No. 150050-20-7. Molecular formula: C37H38O13. Mole weight: 690.7. | |
| Sch 47555 | Sch 47555 is an antifungal antibiotic produced from Streptomyces sp. SCC-2135. Alternative Names: Antibiotic Sch 47555; Sch-47555. CAS No. 150050-21-8. Molecular formula: C37H42O13. Mole weight: 694.7. | |
| Sch 484129 | Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Alternative Names: Sch-484129. Molecular formula: C31H54O12. Mole weight: 618.8. | |
| Sch 484130 | Sch 484130 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains. Alternative Names: Sch-484130. Molecular formula: C31H54O12. Mole weight: 618.8. | |
| Sch 50673 | Sch 50673 is an antitumor metabolite produced by Nattrassia mangiferae. Alternative Names: Sch-50673. Molecular formula: C21H14O8. Mole weight: 394.3. | |
| Sch 50676 | Sch 50676 is an antitumor metabolite produced by Nattrassia mangiferae. Alternative Names: Sch-50676. Molecular formula: C20H14O5. Mole weight: 334.3. | |
| SCH 50911 | SCH 50911 is a selective, orally active, blood-brain barrier permeable GABA-B receptor (GABA-B Receptor) antagonist with an IC50 of 1.1 μM in rats. SCH 50911 blocks baclofen-induced antitussive effects, regulates neuronal firing and GABA release. SCH 50911 promotes spontaneous seizures during withdrawal in ethanol-dependent rats, alters reward-related neurotransmission, and reduces or suppresses lever responding and self-administration behaviors of alcohol and sucrose in rats. SCH 50911 is applicable to research related to ethanol withdrawal syndrome, absence epilepsy and alcohol use disorder[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 733717-87-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12783A. | |
| SCH-50911 | CH-50911 is a selective GABA-B antagonist with IC50 value of 1.1 μM. It is developed by Schering-Plough Corporation. CH-50911 is often used in pharmacology research and it also acts as an anticonvulsant under normal conditions. Preclinical trials for Absence seizures and Cognition disorders in USA were discontinued. Uses: Absence epilepsy; cognition disorders. Alternative Names: SCH-50911; SCH 50911; SCH50911; (S)-2-(5,5-dimethylmorpholin-2-yl)acetic acid. Grades: 98%. CAS No. 733717-87-8. Molecular formula: C8H15NO3. Mole weight: 173.21. | |
| SCH 51344 | SCH 51344. Group: Biochemicals. Grades: Purified. CAS No. 171927-40-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 527123 | A potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively. Alternative Names: 2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide; SCH527123; SCH-527123; SCH 527123; MK-7123; MK7123; MK 7123; PS291822; PS-291822; PS 291822; Navarixin monohydrate; Navarixin. CAS No. 473727-83-2. Molecular formula: C21H23N3O5. Mole weight: 397.42. | |
| Sch 528647 | Sch 528647 is an antitumor antibiotic produced by Aspergillus fumigatus. Alternative Names: Sch-528647. Molecular formula: C26H34O6. Mole weight: 442.5. | |
| Sch 52900 | Sch 52900 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Alternative Names: Sch-52900. Molecular formula: C31H30N6O7S4. Mole weight: 726.9. | |
| Sch 52901 | Sch 52901 is an inhibitor of c-fos proto-oncogene induction, which is isolated from the fermentation of broth of the fungal culture (SCF-1168), Gliocladium sp. Alternative Names: Sch-52901. Molecular formula: C31H30N6O6S4. Mole weight: 710.9. | |
| SCH529074 | SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 μM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 922150-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110088. | |
| SCH 529074 | SCH 529074. Group: Biochemicals. Grades: Purified. CAS No. 922150-11-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 546738 | SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist with Ki of 0.4 nM. Alternative Names: SCH546738; SCH 546738; SCH-546738; 3-amino-6-chloro-5-[(3S)-4-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-ethylpiperazin-1-yl]pyrazine-2-carboxamide. CAS No. 906805-42-3. Molecular formula: C23H31Cl2N7O. Mole weight: 492.44. | |
| SCH 546738 | SCH 546738 is a potent, orally active and non-competitive CXCR3 antagonist, the affinity constant (Ki) of SCH 546738 binding to human CXCR3 receptor is determined to be 0.4 nM in multiple experiments. Uses: Scientific research. Category: Signaling pathways. CAS No. 906805-42-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10017. | |
| Sch 56396 | Sch 56396 is a c-fos proto-oncogene inhibitor produced by the fungus Tolypocladium sp. Alternative Names: Sch-56396. Molecular formula: C17H20N2O3S. Mole weight: 332.4. | |
| Sch 57404 | Sch 57404 is an antifungal antibiotic produced by an unidentified fungus SCF1082A. Alternative Names: Sch-57404. Molecular formula: C27H36O9. Mole weight: 504.6. | |
| Sch 575867 | Sch 575867 is an antifungal antibiotic isolated from a deep-water marine sponge Astroscleridae. It is effective against brewer's yeast with MIC of 15 μg/mL. Alternative Names: Sch-575867. Molecular formula: C32H51Na3O13S3. Mole weight: 808.9. | |
| Sch 58053 | Sch 58053 is an analog of Ezetimibe and a selective inhibitor of lymphatic cholesterol transport in the intestine. Category: Active pharmaceutical ingredients. CAS No. 194423-53-5. Product ID: API194423535. Molecular formula: C26H23ClFNO3. Mole weight: 451.92. |  |
| SCH 58261 | SCH 58261. Group: Biochemicals. Grades: Purified. CAS No. 160098-96-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH 58261 | SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160098-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19533. | |
| SCH 58261 | SCH 58261 is a potent and selective antagonist of adenosine A2A receptor, displaying neuroprotective activity. Uses: Adenosine a2 receptor antagonists. Alternative Names: SCH-58261; SCH 58261; SCH58261. 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine. Grades: 98%. CAS No. 160098-96-4. Molecular formula: C18H15N7O. Mole weight: 345.366. | |
| Sch 599473 | Sch 599473 is a sesterterpene isolated from from a marine sponge, Ircinia sp. It inhibits CCR7 receptor with IC50 of 33 μg/mL. Alternative Names: Sch-599473. Molecular formula: C25H40O5S. Mole weight: 452.6. | |
| Sch 725674 | It is a macrocyclic lactone structurally related to gloeosporone. It is a self-germination inhibitor produced by colletotrichum gloeosporioides. It exhibits moderate antifungal activity. Alternative Names: Antibiotic Sch 725674; (3E,5R,6S,8R,14R)-5,6,8-Trihydroxy-14-pentyloxacyclotetradec-3-en-2-one; Sch-725674; 5R,6S,8R-trihydroxy-14R-pentyl-oxacyclotetradec-3E-en-2-one. Grades: >95% by HPLC. CAS No. 877061-66-0. Molecular formula: C18H32O5. Mole weight: 328.44. | |
| SCH772984 | SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 values of 4 nM and 1 nM in cell-free assay, respectively, And show robust efficacy in RAS- or BRAF-mutant cancer cells. Group: Inhibitors. CAS No. 942183-80-4. Pack Sizes: 5mg. Product ID: S7101. Formula: C33H33N9O2. Smiles: C1CN(CC1C(=O)NC2=CC3=C(C=C2)NN=C3C4=CC=NC=C4)CC(=O)N5CCN(CC5)C6=CC=C(C=C6)C7=NC=CC=N7. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| SCH772984 | SCH772984 is a potent and selective ERK inhibitor with potential anticancer activity. SCH722984 showed activity against BRAF mutant, NRAS mutant and wild-type melanoma. Combining vemurafenib and SCH722984 in BRAF mutant melanoma was synergistic in a majority of cell lines and significantly delayed the onset of acquired resistance in long term in vitro assays. Therefore, SCH772984 may be clinically applicable as a treatment for non-BRAF mutant melanoma or in BRAF-mutant melanoma with innate or acquired resistance, alone or in combination with BRAF inhibitors. Alternative Names: SCH-772984; SCH 772984; (R)-1-(2-oxo-2-(4-(4-(pyrimidin-2-yl)phenyl)piperazin-1-yl)ethyl)-N-(3-(pyridin-4-yl)-1H-indazol-5-yl)pyrrolidine-3-carboxamide. Grades: 95%. CAS No. 942183-80-4. Molecular formula: C33H33N9O2. Mole weight: 587.688. | |
| SCH772984 | SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-na?ve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 942183-80-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50846. | |
| SCH772984 | SCH772984 Inhibitor. Uses: Scientific use. Product Category: T6066. CAS No. 942183-80-4. |  |
| SCH79797 | SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. SCH79797 inhibits binding of a high-affinity thrombin receptor-activating peptide to PAR1 with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 inhibits thrombin-induced platelet aggregation with an IC50 of 3 μM. SCH79797 has antiproliferative and pro-apoptotic effects, and limits myocardial ischemia/reperfusion injury in rat hearts. SCH79797 also potently prevents PAR1 activation in vascular smooth muscle cells, endothelial cells, and astrocytes[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 245520-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14993. | |
| SCH 79797 dihydrochloride | SCH 79797 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216720-69-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SCH-900271 | SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 915210-50-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-111143. | |
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