A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
100g Pack Size. Group: Building Blocks, Organics. Formula: CH5N3O · HCl. CAS No. 563-41-7. Prepack ID 12845490-100g. Molecular Weight 111.53. See USA prepack pricing.
Semicarbazide hydrochloride
500g Pack Size. Group: Building Blocks, Organics. Formula: CH5N3O · HCl. CAS No. 563-41-7. Prepack ID 12845490-500g. Molecular Weight 111.53. See USA prepack pricing.
Semicarbazide hydrochloride
Semicarbazide hydrochloride. Group: Biochemicals. Alternative Names: Hydrazinecarboxamide monohydrochloride; Aminourea hydrochloride. Grades: Highly Purified. CAS No. 563-41-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: CH6ClN3O. US Biological Life Sciences.
Semilicoisoflavone B is a compound of the flavonoid class found in the roots of Glycyrrhiza uralensis Fisch. Study shows that Semilicoisoflavone B inhibits sorbitol formation of rat lens incubated with a high concentration of glucose. Alternative Names: 5,7,8'-Trihydroxy-2',2'-dimethyl-2'H-(3,6')bi(1-benzopyranyl)-4-one; 4H-1-Benzopyran-4-one,5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-. Grades: >98%. CAS No. 129280-33-7. Molecular formula: C20H16O6. Mole weight: 352.342.
Semilicoisoflavone B
Semilicoisoflavone B. Group: Biochemicals. CAS No. 129280-33-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Semilicoisoflavone B
Semilicoisoflavone B. Alternative Names: 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-. CAS No. 129280-33-7. Product ID: FFC-AR-129280337. Molecular formula: C20H16O6. Mole weight: 352.34. IUPAC Name: 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one. Alfa Chemistry - ISO 9001:32057 Certified.
Seminalplasmin
Seminalplasmin is an antibacterial peptide isolated from Bovine Bos taurus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ser-Asp-Glu-Lys-Ala-Ser-Pro-Asp-Lys-His-His-Arg-Phe-Ser-Leu-Ser-Arg-Tyr-Ala-Lys-Leu-Ala-Asn-Arg-Leu-Ala-Asn-Pro-Lys-Leu-Leu-Glu-Thr-Phe-Leu-Ser-Lys-Trp-Ile-Gly-Asp-Arg-Gly-Asn-Arg-Ser-Val. CAS No. 147958-06-3. Molecular formula: C76H123N17O16. Mole weight: 1530.9.
Semorinemab
Semorinemab (RG 6100) is an anti-Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a Kd value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG 6100; RO7105705; MTAU-9937A. CAS No. 2159141-27-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99399.
Sempervirin
Sempervirine is an indole alkaloid isolated from Gelsemium elegans. It exhibits a selective inhibitory effect on in vitro synthesis of cancer DNA. Alternative Names: 1,2,3,4-tetrahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline. Grades: 98.0%. CAS No. 6882-99-1. Molecular formula: C19H16N2. Mole weight: 272.4.
Semustine
Semustine is an alkylating agent and interstrand DNA cross linker. Anti-cancer chemotherapeutic agents, which are used in the treatment of different types of cancer such as brain tumors, resistant Hodgkin s disease, lung cancer and malignant melanoma. Group: Biochemicals. Grades: Highly Purified. CAS No. 13909-09-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H18ClN3O2, Molecular Weight: 247.72. US Biological Life Sciences.
Worldwide
Semzuvolimab
Semzuvolimab is a human IgG1κ antibody, targeting to p55, T cell surface antigen T4/Leu-3 (CD4). Human CD4 antibodies can neutralize HIV infection and have the potential to inhibit HAART stable HIV infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UB421. CAS No. 2409099-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9998.
SEN 12333
SEN 12333. Group: Biochemicals. Grades: Purified. CAS No. 874450-44-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SEN 1269
SEN 1269. Group: Biochemicals. Grades: Purified. CAS No. 956128-01-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SEN177
SEN177 is an orally effect glutamine cyclase (QC) inhibitor. The Ki of SEN177 for human glutamine cyclase (hQC) is 20 nM, and the IC50 is 13 nM. SEN177 interferes with the interaction between CD47 and SIRRPα, and has anti-tumor activity. SEN177 reduces aggregation and apoptosis caused by HTT mutation in Huntington model, and can be used in the study of neurodegenerative diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2117405-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-136780.
Senaparib
Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMP4297; JS109. CAS No. 1401682-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137450.
Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH)[1][2][3]. Uses: Scientific research. Category: Natural products. Alternative Names: Senecionan-11,16-dione, 12-hydroxy-; Aureine; Senecionin. CAS No. 130-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2560.
SENECIONINE
Senecionine is a pyrrolizidine alkaloid isolated from Senecio scandens. Study shows that senecionine exhibits activity against hepatic drug metabolizing enzymes in rat cells. Alternative Names: Aureine; Senecionin; 12-Hydroxysenecionan-11,16-dione. Grades: 97.5%. CAS No. 130-01-8. Molecular formula: C18H25NO5. Mole weight: 335.4.
Senecionine N-oxide. Alternative Names: 12-Hydroxysenecionan-11,16-dione 4-oxide. CAS No. 13268-67-2. Product ID: FFC-AR-13268672. Molecular formula: C18H25NO6. Mole weight: 351.39. IUPAC Name: (1R,4Z,6R,7R,17R)-4-ethylidene-7-hydroxy-6,7-dimethyl-14-oxido-2,9-dioxa-14-azoniatricyclo[9.5.1.014,17]heptadec-11-ene-3,8-dione. Alfa Chemistry - ISO 9001:32057 Certified.
Senecionine N-Oxide
Senecionine N-Oxide is an alkaloid isolated from Senecio vulgaris showing anti-cancer activity. Alternative Names: Senecionine oxide; 12-Hydroxysenecionan-11,16-dione 4-oxide. Grades: 98%. CAS No. 13268-67-2. Molecular formula: C18H25NO6. Mole weight: 351.17.
senecionine N-oxygenase
A flavoprotein. NADH cannot replace NADPH. While pyrrolizidine alkaloids of the senecionine and monocrotaline types are generally good substrates (e.g. senecionine, retrorsine and monocrotaline), the enzyme does not use ester alkaloids lacking an hydroxy group at C-7 (e.g. supinine and phalaenopsine), 1,2-dihydro-alkaloids (e.g. sarracine) or unesterified necine bases (e.g. senkirkine) as substrates. Senecionine N-oxide is used by insects as a chemical defense: senecionine N-oxide is non-toxic, but it is bioactivated to a toxic form by the action of cytochrome P-450 oxidase when absorbed by insectivores. Group: Enzymes. Synonyms: senecionine monooxygenase (N-oxide-forming); SNO. Enzyme Commission Number: EC 1.14.13.101. CAS No. 220581-68-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0700; senecionine N-oxygenase; EC 1.14.13.101; 220581-68-0; senecionine monooxygenase (N-oxide-forming); SNO. Cat No: EXWM-0700.
Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase. Alternative Names: Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione. Grades: >98%. CAS No. 480-81-9. Molecular formula: C18H23NO5. Mole weight: 333.4.
Seneciphylline N-oxide is a natrual alkaloids found in the herbs of Senecio scandens. Alternative Names: (3Z,6R,14aR,14bR)-3-Ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-methyl-5-methylene-[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione 12-Oxide; 13,19-Didehydro-12-hydroxysenecionan-11,16-dione 4-Oxide. Grades: >98%. CAS No. 38710-26-8. Molecular formula: C18H23NO6. Mole weight: 349.4.
Seneciphyllinine
Seneciphyllinine is an alkaloid isolated from Gynura segetum. Alternative Names: 12-Acetylseneciphylline; Acetylseneciphylline; O-acetylseneciphylline; Seneciphylline acetate. Grades: 60.0%. CAS No. 90341-45-0. Molecular formula: C20H25NO6. Mole weight: 375.421.
Senegalin
Senegalin is an antibacterial peptide isolated from Kassina senegalensis. It has activity against gram-positive bacteria and fungi. Alternative Names: Phe-Leu-Pro-Phe-Leu-Ile-Pro-Ala-Leu-Thr-Ser-Leu-Ile-Ser-Ser-Leu. Grades: >96%. Molecular formula: C375H613N103O119S3. Mole weight: 1732.14.
Seneganolide
Seneganolide isolated from the heartwood of Khaya senegalensis. Uses: Antifungal activity. Alternative Names: (1S,2R,6R,7R,10R,11S,16S,20R)-6-(3-Furyl)-20-hydroxy-7,17,17-trimethyl-5,13,21-trioxahexacyclo[17.2.1.01,10.02,7.011,16.011,20]docosane-4,14,18-trione. Grades: > 95%. CAS No. 301530-12-1. Molecular formula: C26H30O8. Mole weight: 470.5.
Senegenin
Senegenin. Group: Biochemicals. Grades: Highly Purified. CAS No. 2469-34-3. Pack Sizes: 20mg. Molecular Formula: C30H45CIO6. US Biological Life Sciences.
Worldwide
Senexin A
Senexin A is an inhibitor of CDK8/19 (IC50: 280 nM, CDK8) and an inhibitor downstream of p21 transcription. It only inhibits p21-induced transcription but does not inhibit other biological effects of p21. Senexin A inhibits CMV-GFP induction as well as the p21 stimulatory activity of the consensus NF-κB-dependent promoters[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1366002-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15681.
Senexin B
Senexin B (SNX2-1-165; BCD-115) is a potent, highly water-soluble and bioavailable CDK8/19 inhibitor, with Kds of 140 nM for CDK8 and 80 nM for CDK19. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SNX2-1-165; BCD-115. CAS No. 1449228-40-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101800.
Senexin C
Senexin C is a selective and orally active CDK8/19 inhibitor. Senexin C shows a strong tumor-enrichment pharmacokinetic (PK) profile and tumor-pharmacodynamic (PD) marker responses. Senexin C inhibits the growth of MV4-11 leukemia cells with good tolerability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375554-02-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143889.
Senfolomycin A
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Alternative Names: Paulomycin E; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-(4-C-acetyl-2,6-dideoxy-3-O-methyl-a-L-xylo-hexopyranosyl)-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-butenyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BA. CAS No. 11017-36-0. Molecular formula: C29H36N2O16S. Mole weight: 700.66.
Senfolomycin B
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Alternative Names: Paulomycin F; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-(1-hydroxyethyl)-3-O-methyl-α-L-xylo-hexopyranosyl]-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BB. CAS No. 11031-56-4. Molecular formula: C29H38N2O16S. Mole weight: 702.68.
Senicapoc
Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694.
Senicapoc
Senicapoc, previously called as ICA 17043, is a small organic potent and selective blocker of the Gardos channel which is the calcium-activated potassium channel located on the human RBC, inhibiting the efflux of K+ through this channel. Alternative Names: 2,2-bis(4-fluorophenyl)-2-phenylacetamide; bis(4-fluorophenyl)phenylacetamide; ICA 17043; ICA-17043; ICA17043. CAS No. 289656-45-7. Molecular formula: C20H15F2NO. Mole weight: 323.34.
Seniprutug
Seniprutug is an anti-TRBV9 human IgG1 κ monoclonal antibody[1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: BCD-180. CAS No. 2484772-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990762.
Senktide
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50=0.5-3 nM). Senktide less potently agonizes the NK1 receptor (EC50=35 μM). Senktide is promising for research of neurological disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 106128-89-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0187.
Senktide
Senktide. Group: Biochemicals. Grades: Purified. CAS No. 106128-89-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Senktide
Senktide is a potent tachykinin NK3 receptor agonist. It exhibits a less potent effect on the NK1 receptor (EC50 = 35 μM) and no effect on the NK2 receptor. Senktide was demonstrated the stimulation of dopamine neurons and the enhancement of dopaminergic function. Alternative Names: [Succinyl-Asp6, NMePhe8]-Substance P (6-11); N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide. Grades: >97%. CAS No. 106128-89-6. Molecular formula: C40H55N7O11S. Mole weight: 842.
Senkyunolide A
Senkyunolide A is isolated from Ligusticum chuanxiong Hort and shows cytoprotective, antiproliferative, and anti-tumor activity. Alternative Names: 1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)-; (3S)-3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone; 1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-; (-)-Sedanenolide; (S)-Sedanenolide; (S)-3-n-Butyl-4,5-dihydrophthalide; Sedanenolide; Senkyunolide. Grades: >95%. CAS No. 63038-10-8. Molecular formula: C12H16O2. Mole weight: 192.25.
Senkyunolide A
Senkyunolide A. Group: Biochemicals. Alternative Names: Sedanenolide; 3-Butyl-4,5-dihydrophthalide; Senkyunolide. Grades: Plant Grade. CAS No. 63038-10-8. Pack Sizes: 20mg. Molecular Formula: C12H16O2, Molecular Weight: 192.253999999999. US Biological Life Sciences.
Worldwide
Senkyunolide A
Senkyunolide A is a phthalide, anti-tumor cell proliferation agent with anticancer activity. Senkyunolide A protects neurons from corticosterone (HY-B1618)-induced apoptosis by decreasing protein phosphatase PP2A and α-synuclein phosphorylation and protein level. Senkyunolide A also inhibits osteoarthritis through the NLRP3 signaling pathway and suppresses the expression of CD137, a diagnostic biomarker for atherosclerosis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63038-10-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0743.
Senkyunolide G
Senkyunolide G is a natural compound found in several plants. Alternative Names: 3-Butyl-4,5-dihydro-3-hydroxy-1(3H)-isobenzofuranone. Grades: >95%. CAS No. 94530-85-5. Molecular formula: C12H16O3. Mole weight: 208.25.
Senkyunolide H
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 94596-27-7. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
Worldwide
Senkyunolide I
Senkyunolide I. Group: Biochemicals. Grades: Plant Grade. CAS No. 94596-28-8. Pack Sizes: 20mg. Molecular Formula: C12H16O4, Molecular Weight: 224.25. US Biological Life Sciences.
Worldwide
Senkyunolide I
Senkyunolide I isolated from the roots of Ligusticum chuanxiong hort. It has neuroprotective effect. Uses: Anti-oxidation and anti-apoptosis properties. Alternative Names: (6α,7β)-3-[(Z)-Butylidene]-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone; (3Z,6R,7R)-rel-3-Butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone. Grades: 0.98. CAS No. 94596-28-8. Molecular formula: C12H16O4. Mole weight: 224.3.
Senkyunolide I
Senkyunolide I is an orally active, blood-brain barrier-permeable metabolite of Z-ligustilide (HY-N0401A). Senkyunolide I is isolated from Ligusticum chuanxiong. Senkyunolide I upregulates p-Erk1/2 and Nrf2/HO-1, and inhibits Caspase 3. Senkyunolide I alleviates Apoptosis. Senkyunolide I increases the pain threshold in mice and reduces acetic acid-induced writhing responses in mice. Senkyunolide I improves neurological deficits, reduces infarct volume and alleviates cerebral edema in rats with focal cerebral ischemia-reperfusion injury. Senkyunolide I protects renal function and structural integrity in a mouse model of renal ischemia-reperfusion injury. Senkyunolide I is applicable to research related to focal cerebral ischemia-reperfusion injury, migraine, and renal ischemia-reperfusion injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 94596-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0745.
Senna Leaf Extract
Senna Leaf Extract is the main raw material of Cassia angustifolia Vahl. Its main active ingredients are Sennoside A and B, and contain rhein, aloe-emodin, chrysophanol and other anthraquinones Derivatives and other glycosides. Alternative Names: Senna, Cassia obovata, ext.; Senna extract; Folium Sennae Extract. Grades: 20% (Sennoside A and B). CAS No. 85085-71-8.
Senna Leaf Extract
Senna leaf extract is prepared from a large genus of flowering plant Cassia angustifolia Vahl in the fabaceae family on the tropics. Senna leaf extract have been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components sennoside in senna leaf extract are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides. Group: Others. Mole weight: 862.7391. Senna Leaf Extract; Cassia Angustifolia Vahl. Cat No: EXTC-034.
Senna Leaf P.E. 8% Sennosides UV - Water Soluble
Senna Leaf P.E. 8% Sennosides UV - Water Soluble.
CA, FL & NJ
Senna Leaf Powder
Senna Leaf Powder.
CA, FL & NJ
Sennoside
Sennoside is an anthraquinone derivative found in senna leaves. Sennoside is used as a laxative in the treatment of constipation. Studies have suggested that the use of Sennoside may be associated with genotoxicity and carcinogenicity, but there is currently no conclusive evidence to support this. Alternative Names: [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-; 5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-bianthracene]-2,2'-dicarboxylic acid; Sennoside (Mixture of A and B). CAS No. 517-43-1. Molecular formula: C42H38O20. Mole weight: 862.74.
Sennoside A
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 81-27-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0365.
Sennoside A
Sennoside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 81-27-6. Pack Sizes: 20mg. Molecular Formula: C42H38O20, Molecular Weight: 862.74. US Biological Life Sciences.
Worldwide
Sennoside A
Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. Sennoside A can be used in health products. It is an HIV-1 inhibitor that is effective against HIV-1 replication. Uses: Diarrhea. Alternative Names: (R*,R*)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-Bianthracene]-2,2'-dicarboxylic Acid; Glysennid; NSC 112929; Senokot; (9R,9'R)-5-(β-D-Glucopyranosyloxy)-5'-(D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid; [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5-(β-D-glucopyranosyloxy)-5'-(D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'R)-. Grades: 98%. CAS No. 81-27-6. Molecular formula: C42H38O20. Mole weight: 862.74.
Sennoside B
Sennoside B, a kind of irritant laxative isolated from rhei rhizome, inhibits PDGF-stimulated cell proliferation. Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. Uses: Diarrhea. Alternative Names: 5,5-Bis(b-D-glucopyranosyloxy)-9,9,10,10-tetrahydro-4,4-dihydroxy-10,10-dioxo-(9R,9S)-[9,9-bianthracene]-2,2-dicarboxylic acid. Grades: >98%. CAS No. 128-57-4. Molecular formula: C42H38O20. Mole weight: 862.74.
Sennoside B
Sennoside B. Group: Biochemicals. Alternative Names: Tisasen B. Grades: Plant Grade. CAS No. 128-57-4. Pack Sizes: 20mg. Molecular Formula: C42H38O20, Molecular Weight: 862.739. US Biological Life Sciences.
Worldwide
Sennoside B calcium salt
Sennoside B Calcium Salt, a compound belonging to anthraquinone family, is an efficacious medicine utilized for the treatment of constipation, with its mechanism of action focusing on the stimulation of the colon to induce contractions, resulting in enhanced stool volume and ultimately, promoting natural bowel movements. By presenting itself in the calcium salt form, the product delivers increased solubility and absorption, ensuring optimum effectiveness throughout the gastrointestinal tract. Alternative Names: [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, calcium salt (1:x), (9R,9'S)-; [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, calcium salt, (R*,S*)-. CAS No. 52730-37-7. Molecular formula: C42H38O20.xCa. Mole weight: 862.74 (free acid).
Sennoside C
Aloe-emodin anthrone and rhein anthrone, formed mainly by intraluminal bacterial action, are the true active metabolites of Sennoside C in mice and that both anthrones synergistically exert their purgative effects on mice. Alternative Names: [9,9'-Bianthracene]-2-carboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-, (9R,9'R)-rel-; [9,9'-Bianthracene]-2-carboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-, (R*,R*)-; rel-(9R,9'R)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo[9,9'-bianthracene]-2-carboxylic acid; (R*,R*)-5,5'-bis(β-D-Glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-[9,9'-bianthracene]-2-carboxylic Acid. Grades: 98%. CAS No. 37271-16-2. Molecular formula: C42H40O19. Mole weight: 848.76.
Sennoside C
Sennoside C. Group: Biochemicals. Grades: Plant Grade. CAS No. 37271-16-2. Pack Sizes: 5mg. Molecular Formula: C42H40O19, Molecular Weight: 848.76. US Biological Life Sciences.
Worldwide
Sennoside Calcium Salt (Mixture of A and B)
Sennoside is an anthraquinone derivative found in senna leaves. Sennoside is used as a laxative in the treatment of constipation. Studies have suggested that the use of Sennoside may be associated with genotoxicity and carcinogenicity, but there is currently no conclusive evidence to support this. Alternative Names: (9RS,9'RS)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-[9,9'-bianthracene]-2,2'-dicarboxylic Acid Calcium Salt; Sennoside Calcium Salt (Mixture of A and B); [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, calcium salt (1:1), (9R,9'R)-rel-; [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, calcium salt (1:1), (R*,R*)-; Pursennid; Pursennide; Sennoside Ca. Grades: 95%. CAS No. 62211-03-4. Molecular formula: C42H36CaO20. Mole weight: 900.80.
Sennoside D
Sennoside D belongs to anthranoid family, and is procured from dried leaflets and pods of senna plant. Alternative Names: rel-(9R,9'S)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo[9,9'-bianthracene]-2-carboxylic Acid; (R*,S*)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-2'-(hydroxymethyl)-10,10'-dioxo-[9,9'-bianthracene]-2-carboxylic Acid. Grades: 98%. CAS No. 37271-17-3. Molecular formula: C42H40O19. Mole weight: 848.76.
Sennoside D
Sennoside D. Group: Biochemicals. Grades: Plant Grade. CAS No. 37271-17-3. Pack Sizes: 5mg. Molecular Formula: C42H40O19, Molecular Weight: 848.76. US Biological Life Sciences.
Worldwide
SENP1-IN-3
SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416910-59-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134596.