A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79559-97-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-B0176A.
Sertraline Hydrochloride
Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Category: Active pharmaceutical ingredients. CAS No. 79559-97-0. Product ID: API79559970. Molecular formula: C17H17Cl2N HCl. Mole weight: 342.69.
A selective serotonin reuptake inhibitor. Used as an antidepressant. Group: Biochemicals. Alternative Names: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine, Hydrochloride. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Sertraline Hydrochloride Racemic Mixture
Sertraline Hydrochloride Racemic Mixture. CAS No. 79617-89-3.
Sertraline hydrochloride Related Compound A
Sertraline hydrochloride Related Compound A. Uses: For analytical and research use. CAS No. 79617-99-5. Mole weight: 342.69. Catalog: AP79617995.
Sertraline hydrochloride (Standard)
Sertraline (hydrochloride) (Standard) is the analytical standard of Sertraline (hydrochloride). This product is intended for research and analytical applications. Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 79559-97-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0176AR.
Sertraline Impurity 10
Sertraline Impurity 10. Uses: For analytical and research use. CAS No. 1198084-29-5. Molecular formula: C17H18Cl3N. Mole weight: 342.69. Catalog: APB1198084295.
Sertraline Impurity 11
Sertraline Impurity 11. Uses: For analytical and research use. CAS No. 79836-76-3. Molecular formula: C18H20Cl3N. Mole weight: 356.72. Catalog: APB79836763.
Sertraline Impurity 12
Sertraline Impurity 12. Uses: For analytical and research use. CAS No. 79560-19-3. Molecular formula: C16H12Cl2O. Mole weight: 291.17. Catalog: APB79560193.
Sertraline Impurity 13
Sertraline Impurity 13. Uses: For analytical and research use. CAS No. 79560-20-6. Molecular formula: C17H15Cl2N. Mole weight: 304.21. Catalog: APB79560206.
Sertraline Impurity 17
Sertraline Impurity 17. Uses: For analytical and research use. CAS No. 124345-07-9. Molecular formula: C17H17Cl2NO. Mole weight: 322.23. Catalog: APB124345079.
Sertraline Impurity 19
Sertraline Impurity 19. Uses: For analytical and research use. CAS No. 152448-80-1. Molecular formula: C16H12Cl2O. Mole weight: 291.17. Catalog: APB152448801.
Sertraline Impurity 2
Sertraline Impurity 2. Uses: For analytical and research use. CAS No. 866018-46-4. Molecular formula: C16H14Cl2O. Mole weight: 293.19. Catalog: APB866018464.
Sertraline Impurity 20
Sertraline Impurity 20. Uses: For analytical and research use. CAS No. 152642-35-8. Molecular formula: C16H13Cl2NO. Mole weight: 306.19. Catalog: APB152642358.
Sertraline Impurity 21
Sertraline Impurity 21. Uses: For analytical and research use. CAS No. 4800-46-8. Molecular formula: C16H12Cl2O. Mole weight: 291.17. Catalog: APB4800468.
Sertraline Impurity 22
Sertraline Impurity 22. Uses: For analytical and research use. CAS No. 675126-08-6. Molecular formula: C16H16Cl3N. Mole weight: 328.66. Catalog: APB675126086.
Sertraline Impurity 3
Sertraline Impurity 3. Uses: For analytical and research use. CAS No. 209473-00-7. Molecular formula: C17H15Cl2NO. Mole weight: 320.21. Catalog: APB209473007.
Sertraline Impurity 31
Sertraline Impurity 31. Uses: For analytical and research use. CAS No. 2124277-87-6. Molecular formula: C17H17Cl2N. Mole weight: 306.23. Catalog: APB2124277876.
Sertraline Impurity 4
Sertraline Impurity 4. Uses: For analytical and research use. CAS No. 1498236-91-1. Molecular formula: C16H14Cl2O. Mole weight: 293.19. Catalog: APB1498236911.
Sertraline Impurity 40
Sertraline Impurity 40. Uses: For analytical and research use. Molecular formula: C17H19Cl2N. Mole weight: 308.25. Catalog: APB10826.
Sertraline Impurity 6
Sertraline Impurity 6. Uses: For analytical and research use. CAS No. 79896-32-5. Molecular formula: C17H18Cl3N. Mole weight: 342.69. Catalog: APB79896325.
Sertraline Impurity 8
Sertraline Impurity 8. Uses: For analytical and research use. CAS No. 79617-89-3. Molecular formula: C17H18Cl3N. Mole weight: 342.69. Catalog: APB79617893.
Sertraline Impurity 9
Sertraline Impurity 9. Uses: For analytical and research use. CAS No. 140631-53-4. Molecular formula: C17H17Cl2N. Mole weight: 306.23. Catalog: APB140631534.
Serum-free Media for Exosome Culture
The serum-free media (for exosome culture) is a culture medium specifically designed for the acquisition of exosomes; it is suitable for tumor cells and T cells, etc. Product ID: Exo-0046.
Serum, Human, Myoglobin Free (MB)
Gel for affinity column was prepared by coupling anti-myoglobin monoclonal antibodies (several monoclonal antibodies specific to the N-,C-terminal and central parts of myoglobin molecule) with BrCN-activated Sepharose CL 4B. Group: Biologicals. Grades: Highly Purified. Pack Sizes: 50ml. US Biological Life Sciences.
Worldwide
Serum, Mouse
United States Biological supplies a complete range of animal serum products for use in diagnostics and molecular biology research. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 100ml. US Biological Life Sciences.
Worldwide
Serum thymic factor
Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thymulin; Thymic factor. CAS No. 63958-90-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3206.
Serum thymic factor acetate
Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Thymulin acetate; Thymic factor acetate. CAS No. 125117-65-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3206A.
Seryl-arginine
Seryl-arginine is a dipeptide composed of serine and arginase. Alternative Names: Ser-Arg; L-Seryl-L-arginine. CAS No. 13261-11-5. Molecular formula: C9H19N5O4. Mole weight: 261.28.
Seryl-isoleucine
Seryl-isoleucine is a dipeptide composed of serine and isoleucine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Isoleucine, L-seryl-; Ser-Ile; H-SI-OH; L-seryl-L-isoleucine; L-Ser-L-Ile. Grades: ≥95%. CAS No. 91086-51-0. Molecular formula: C9H18N2O4. Mole weight: 218.25.
Serylleucine
Serylleucine (H-Ser-Leu-OH) is a dipeptide. Serylleucine's core 1 o-glycosylated peptide (SLC1G) can be detected in urine as a metabolite and is a biomarker in TB studies[1]. Uses: Scientific research. Category: Peptides. Alternative Names: H-Ser-Leu-OH; Ser-Leu. CAS No. 6665-16-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P4511.
Seryl-lysine
Seryl-lysine is a dipeptide composed of serine and lysine. Alternative Names: L-Serinyl-L-lysine; seryl lysine. CAS No. 22677-61-8. Molecular formula: C9H19N3O4. Mole weight: 233.26.
Seryl-lysyl-aspartic acid
Seryl-lysyl-aspartic acid. CAS No. 111245-28-4. Product ID: ACM111245284. Alfa Chemistry - ISO 9001:32057 Certified.
Seryl-threonine is a dipeptide composed of serine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: L-Threonine, L-seryl-; L-seryl-L-threonine; Ser-Thr; Serinylthreonine; ST dipeptide; L-Ser-L-Thr. Grades: ≥95%. CAS No. 61043-85-4. Molecular formula: C7H14N2O5. Mole weight: 206.20.
Seryl-tryptophan
Seryl-tryptophan is a dipeptide composed of serine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: Ser-Trp-OH; Ser-Trp; L-Tryptophan, L-seryl-; Seryltryptophan; S-W Dipeptide; Serine Tryptophan dipeptide; L-seryl-L-tryptophan; H-SW-OH. Grades: ≥95%. CAS No. 94421-70-2. Molecular formula: C14H17N3O4. Mole weight: 291.30.
Seryl-Valine
Seryl-Valine is a dipeptide composed of serine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: H-SV-OH; L-seryl-L-valine; L-Valine, L-seryl-; Serinyl-Valine; L-Ser-L-Val. Grades: ≥95%. CAS No. 51782-06-0. Molecular formula: C8H16N2O4. Mole weight: 204.22.
Sesame Co2 Extract
Sesame Co2 Extract. CAS No. 8008-74-0. Kosher: Y. VIGON Item # 504568. Categories: Speciality Ingrdients Suppliers, Flavors, Fragrances, Perfumers, Aromatherapy, Essetial Oils.
America & Internationally
Sesame oil
100g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks, Flavours and Fragrance Materials. Formula: N/A. CAS No. 8008-74-0. Prepack ID 55768622-100g. See USA prepack pricing.
Sesame oil
Sesamol is a natural organic compound which is a component of sesame oil. It is a white crystalline solid that is a derivative of phenol. It is sparingly soluble in water, but miscible with most oils. Synonyms: 5-Benzodioxolol; 3, 4-(Methylenedioxy)phenol; 5-hydroxy-1, 3-benzodioxolane; 1, 3-Benzodioxol-5-ol; 4, 5-methylenedioxyphenol. CAS No. 533-31-3. Product ID: PE-0267. Molecular formula: C7H6O3. Mole weight: 138.121. Category: Carrier Excipients; Ointment Base. Product Keywords: Pharmaceutical Excipients; Excipients for Semi-solid Dosage Form; Ointment Base; Sesame oil; PE-0267; C7H6O3; 533-31-3; 533-31-3. Appearance: White to off-white crystalline powder. EC Number: 208-561-5. Storage: -20ºC. Boiling Point: 274ºC at 760 mmHg. Melting Point: 63-65ºC. Density: 1.394 g/cm3.
Sesame oil
Sesame oil. CAS No. 8008-74-0. Purity: 0.98. Product ID: CI-EO-0068. Alfa Chemistry - ISO 9001:32057 Certified.
Sesame Oil
sesame oil's composition makes it suitable for creating structured oils used in drug delivery systems. Grades: Pharmaceutical grade. Product ID: PE-0363.
Sesame Oil
Sesame Oil is a vegetable oil. Sesame Oil can be extracted from the seeds of Sesamum indicum L. Sesame Oil decreases NF-κB, aspartate aminotransferase, alanine aminotransferase, IL-1β, IL-4 and nitric oxide. Sesame Oil has antitumor activity against malignant melanoma. Sesame Oil has protective effects against liver damage caused by various agents such as Cisplatin (HY-17394) and Acetaminophen (HY-66005). Sesame Oil shows antinociceptive and anti-inflammatory activities[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8008-74-0. Pack Sizes: 50 mL; 100 mL. Product ID: HY-154629.
Sesame Oil Related Compound A
Sesame Oil Related Compound A. Uses: For analytical and research use. CAS No. 2190-21-8. Mole weight: 881.40. Catalog: AP2190218-A.
Sesame Oil Related Compound B
Sesame Oil Related Compound B. Uses: For analytical and research use. CAS No. 2190-15-0. Mole weight: 855.36. Catalog: AP2190150-A.
Sesame Seed Oil
Organic sesame seed oil, unrefined, expeller-pressed; contains natural vitamins A and E. CAS No. 8008-74-0. Product ID: CI-SC-0479. Alfa Chemistry - ISO 9001:32057 Certified.
Sesamin
Sesamin. Alternative Names: Tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan. CAS No. 607-80-7. Purity: 98%. Product ID: ACM607807-2. Molecular formula: C20H18O6. Mole weight: 354.35. IUPAC Name: 5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole. Canonical SMILES: C1[C@H]2[C@H](CO[C@@H]2C3=CC4=C(C=C3)OCO4)[C@H](O1)C5=CC6=C(C=C5)OCO6. Alfa Chemistry - ISO 9001:32057 Certified.
Sesamin
A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expression of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level. Group: Biochemicals. Alternative Names: (1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole; (+)-Sesamin; ; Fagarol; NSC 36403; Sesamin; Sezamin; d-Sesamin; 5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole; [1S-(1α, 3aα, 4α, 6aα)]-5, 5'-(Tetrahydro-1H, 3H-furo[3, 4-c]furan-1, 4-diyl)bis-1, 3-benzodioxole; Tetrahydro-1, 4-bis[3, 4- (methylenedioxy) phenyl]-1H, 3H-furo[3, 4-c]furan; (1S, 3aR, 4S, 6aR) -Tetrahydro-1, 4-bis[3, 4- (methylenedioxy) phenyl]-1H, 3H-Furo[3, 4-c]furan. Grades: Highly Purified. CAS No. 607-80-7. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Sesamin
Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 607-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0121.
Sesamin
Sesamin is a lignan isolated from the bark of Fagara plants and from sesame oil. It acts as a non-competitive inhibitor of Δ5-desaturase, and reduces cholesterol. Uses: Anti-fibrotic; anti-oxidative. Alternative Names: Fagarol; Sezamin; Asarinin; Pseudocubebin; 5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole. Grades: ≥ 98%. CAS No. 607-80-7. Molecular formula: C20H18O6. Mole weight: 354.358.
Sesamol
Sesamol is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine. Group: Biochemicals. Alternative Names: 1,3-Benzodioxol-5-ol; 3, 4- (Methylenedioxy) phenol; 4-Hydroxy-1,2-methylenedioxybenzene; 5-Hydroxy-1,3-benzodioxole; NSC 59256. Grades: Highly Purified. CAS No. 33-31-3. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
sesamolin
Sesamin and sesamolin have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Alternative Names: (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. Grades: >98%. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36.
Sesamolin
Sesamolin. Group: Biochemicals. Grades: Plant Grade. CAS No. 526-07-8. Pack Sizes: 10mg. Molecular Formula: C20H18O7, Molecular Weight: 370.35. US Biological Life Sciences.
Worldwide
Sesamoside
Sesamoside. Group: Biochemicals. Grades: Plant Grade. CAS No. 117479-87-5. Pack Sizes: 10mg. Molecular Formula: C17H24O12, Molecular Weight: 420.37. US Biological Life Sciences.
Worldwide
Sesbanimide A
Sesbanimide A. CAS No. 85719-78-4. Molecular formula: C15H21NO7. Mole weight: 327.33.
Sesquin
SaBD is an antibacterial peptide isolated from Vigna unguiculata subsp. sesquipedalis. It has activity against gram-positive bacteria, gram-negative bacteria, viral and fungi. Alternative Names: Lys-Thr-Cys-Glu-Asn-Leu-Ala-Asp-Thr-Tyr. Molecular formula: C48H76N12O19S. Mole weight: 1157.26.
sesquithujene synthase
The enzyme from Zea mays, variety Delprim, gives mainly sesquithujene with (S)-β-bisabolene and (E)-β-farnesene plus traces of other sesquiterpenoids, cf. EC 4.2.3.55 [(S)-β-bisabolene synthase] and EC 4.2.3.47 (β-farnesene synthase). It requires Mg2+ or Mn2+. The exact product ratio is dependent on which metal ion is present. Group: Enzymes. Synonyms: TPS5-Del1. Enzyme Commission Number: EC 4.2.3.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5113; sesquithujene synthase; EC 4.2.3.102; TPS5-Del1. Cat No: EXWM-5113.
Sessilifoline A
Sessilifoline A is a natural alkaloid found in the roots of Stemona japonica. Alternative Names: (1S,3S,5R,6S,7R,10S,11R,12R,16S)-11-Ethyl-7-methyl-3-[(2S,4S)-4-methyl-5-oxotetrahydro-2-furanyl]-9,17-dioxa-2-azapentacyclo[10.5.0.01,5.02,16.06,10]heptadecan-8-one. Grades: >95%. CAS No. 929637-35-4. Molecular formula: C22H31NO5. Mole weight: 389.5.
SET2
SET2 is a selective TRPV2 antagonist (IC50=0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2313525-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132222.
Setanaxib
Setanaxib (GKT137831) is a selective NADPH oxidase (NOX1/4) inhibitor with Kis of 140 and 110 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GKT137831; GKT831. CAS No. 1218942-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-12298.
Setanaxib (GKT137831)
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis. Group: Inhibitors. Alternative Names: GKT831. CAS No. 1218942-37-0. Pack Sizes: 5mg. Product ID: S7171. Formula: C21H19ClN4O2. Smiles: CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
SETDB1-TTD-IN-1
SETDB1-TTD-IN-1 is a SETDB1 methyltransferase activator and SETDB1-TTD competitive inhibitor (Kd of 88 nM), and selectivity for SETDB1-TTD over other tudor and bromodomain proteins. SETDB1-TTD-IN-1 stimulates methyltransferase activity via increased catalytic activity, promotes Akt1 Lys64 methylation, Akt1 Thr308 phosphorylation and activation. SETDB1-TTD-IN-1 prevents SETDB1-TTD-histone H3 peptide association, induces global gene expression changes, exhibits cellular target engagement, and acts as a tool compound for SETDB1-TTD function exploration. SETDB1-TTD-IN-1 can be used for the research of breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2755823-12-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141539.
S-Ethyl-CoA
S-Ethyl-CoA is a crucial molecule involved in various metabolic pathways acting as a coenzyme required for the biosynthesis of essential biomolecules, including lipids and amino acids. S-Ethyl-CoA is vital for the production of acetylcholine, playing a crucial role in neurological processes. Alternative Names: S-Ethyl-Coenzym A, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C23H40N7O16P3S (free acid). Mole weight: 795.58 (free acid).
S-Ethylglutathione
S-Ethylglutathione. Group: Biochemicals. Alternative Names: L-gamma-Glutamyl-S-ethyl-L-cysteinyl-glycine; N-[1-[ (Carboxymethyl) carbamoyl]-2- (ethylthio) ethyl]glutamine; N-(S-Ethyl-N-L-gamma-glutamyl-L-cysteinyl)-Glycine. Grades: Highly Purified. CAS No. 24425-52-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C12H21N3O6S. US Biological Life Sciences.
S-Ethyl N-phenylisothio urea. Group: Biochemicals. Alternative Names: N-Phenyl-carbamimidothioic acid ethyl ester; 2-Ethyl-1-phenyl-2-thio-pseudourea. Grades: Highly Purified. CAS No. 19801-34-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C9H12N2S. US Biological Life Sciences.
Worldwide
S-Ethyl trifluorothioacetate 98+%
S-Ethyl trifluorothioacetate 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 383-64-2. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Set I
One unit is defined as the amount of enzyme required to cleave 1 pmol of the double-stranded oligonucleotide of the below indicated structure in 1 hour at 55°C in a total reaction volume of 20 μl. Note! seti cleaves a canonical site and several other sites with a weaker activity. in the case of long incubation with seti dna can be digested to small oligos. Applications: After 5-fold overdigestion with enzyme, approximately 50% of the pbr322 dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. ASST↑ ↓TSSA. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Set I gene from Streptomyces werraensis 37. Pack: 10 mM Tris-HCl (pH 7.6); 100 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 50% glycerol. Cat No: ET-1171RE.
Setidegrasib
Setidegrasib (KRAS G12D inhibitor 17, ASP3082) is a PROTAC KRAS degrader (DC50: 37 nM). Setidegrasib induces the degradation of G12D-mutation KRAS protein. Setidegrasib suppresses p-ERK, p-AKT, p-S6 levels in AsPC-1 cells. Setidegrasib exhibits anti-tumor activity in various cancer xenograft models in mice. Setidegrasib can be used for the study of KRAS(G12D)-mutated solid tumors. (Blue: VHL ligase ligand (HY-168699); Black: linker (HY-168698); Pink: G12D ligand (HY-168700))[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP-3082; KRAS G12D inhibitor 17. CAS No. 2821793-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148273.
Setidegrasib (ASP3082)
ASP3082 (Setidegrasib; KRAS G12D inhibitor 17) is a PROTAC degrader targeting KRAS(G12D) with a DC50 of 38 nM. It effectively inhibits growth in various KRAS(G12D)-mutated cancer cell lines, including pancreatic (PK-59, HPAC) and colorectal (GP2d, GP5d) with IC50 values ranging from 3.6 to 29 nM. Group: Inhibitors. Alternative Names: ASP-3082; KRAS G12D inhibitor 17. CAS No. 2821793-99-9. Pack Sizes: 1mg. Product ID: E4757. Formula: C60H65FN12O7S. Smiles: CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C([C@H](C(C)C)N4C=C(N=N4)C5=CC=C(C=C5)COC6=[C@]([C@]7=C(C(F)=CC8=C7C=NN8)C)C(C9CC9)=CC%10=C6N=C(N=C%10N%11C[C@@H]%12C[C@H]%11CN%12)OC%13CCOCC%13)=O)O)=O)CO.