A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Semapimod (INN), formerly known as CNI-1493, is a cytokine inhibitor. Semapimod is an investigational new drug which has anti-inflammatory, anti-cytokine, immunomodulatory, antiviral and antimalarial properties. Structurally, semapimod is synthetic guanylhydrazone mitogen-activated protein kinase blocker, as a potential treatment for Crohn's disease and other inflammatory conditions. Clinical trials of Semapimod started in 2001. Synonyms: CNI-1493; CNI 1493; CNI1493; AXD455; AXD 455; AXD-455; AIDS121302; AIDS-121302; AIDS 121302. Grades: >98%. CAS No. 164301-51-3. Molecular formula: C34H56Cl4N18O2. Mole weight: 890.746.
Sematilide, also known as CK-1752, is a class III antiarrhythmic compound showing selective delayed rectifier K+ current channel blocking. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness. Uses: Anti-arrhythmia agents. Synonyms: Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monohydrochloride; Sematilide hydrochloride; Sematilide HCl; Sematilide hydrochloride; Sematilide; CK-1752A; CK1752A; CK 1752A; CK-1752; CK1752; CK 1752. CAS No. 101526-62-9. Molecular formula: C14H24ClN3O3S. Mole weight: 349.87.
Semax
Semax is a peptide analog of adrenocorticotropic hormone (ACTH) (4-10). ACTH is a tropic hormone produced by the anterior pituitary. Uses: Enzyme inhibitors. Synonyms: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH; L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-; L-Methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline; L-Proline, 1-[N-[1-[N-[N-(N-L-methionyl-L-α-glutamyl)-L-histidyl]-L-phenylalanyl]-L-prolyl]glycyl]-; ACTH (4-7), Pro-Gly-Pro-; Pro-gly-pro-ACTH (4-7). Grades: 98%. CAS No. 80714-61-0. Molecular formula: C37H51N9O10S. Mole weight: 813.92.
Semax acetate
Semax acetate is a synthetic adrenocorticotropic hormone (ACTH) (4-10) peptide analog with neuroprotective, analgesic, and anti-anxiety properties. Synonyms: L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-, acetate (1:1); H-Met-Glu-His-Phe-Pro-Gly-Pro-OH acetate; L-Methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline acetate; L-Proline, 1-[N-[1-[N-[N-(N-L-methionyl-L-α-glutamyl)-L-histidyl]-L-phenylalanyl]-L-prolyl]glycyl]-, acetate. Grades: ≥95%. CAS No. 2828433-33-4. Molecular formula: C39H55N9O12S. Mole weight: 873.98.
Semax acetate
Semax acetate is a nootropic neuroprotective peptide. Semax acetate can be used in the research of brain stroke [1]. Uses: Scientific research. Group: Peptides. CAS No. 2828433-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1146A.
Semaxanib
Semaxanib is a quinolone derivative with potential antineoplastic activity. Semaxanib reversibly inhibits ATP binding to the tyrosine kinase domain of vascular endothelial growth factor receptor 2 (VEGFR2), which may inhibit VEGF-stimulated endothelial cell migration and proliferation and reduce the tumor microvasculature. This agent also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. Uses: Angiogenesis inhibitors. Synonyms: SU5416; SU-5416; SU 5416; Sugen 5416; semoxind. Grades: 98%. CAS No. 204005-46-9. Molecular formula: C15H14N2O. Mole weight: 238.28.
SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1443448-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-124651.
Semen Cassiae Extract. Applications: Used for health care products, dietary supplements, good for eyesight. Group: Others. Synonyms: Semen Cassiae Extract; Cassia obtusifolia L. Purity: 5:1, 10?1 By TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Seed. Species: Cassia obtusifolia L. Semen Cassiae Extract; Cassia obtusifolia L.; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-108.
semenogelase
A peptidase of family S1 (trypsin family) from seminal plasma. Slowly inhibited by α1-antichymotrypsin. Group: Enzymes. Synonyms: prostate-specific antigen; α-seminoprotein; seminin; P-30 antigen; antigen (human clone HPSA-1 prostate-specific protein moiety reduced); γ-seminoglycoprotein (human protein moiety reduced); γ-SM; antigen PSA (human prostate-specific); human glandular kallikrein; antigen PSA (human clone 5P1 protein moiety reduced). Enzyme Commission Number: EC 3.4.21.77. CAS No. 110157-83-0, 95829-41-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4169; semenogelase; EC 3.4.21.77; 110157-83-0, 95829-41-7; prostate-specific antigen; α-seminoprotein; seminin; P-30 antigen; antigen (human clone HPSA-1 prostate-specific protein moiety reduced); γ-seminoglycoprotein (human protein moiety reduced); γ-SM; antigen PSA (human prostate-specific); human glandular kallikrein; antigen PSA (human clone 5P1 protein moiety reduced). Cat No: EXWM-4169.
Se-Methylselenocysteine, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine is orally bioavailable, and induces apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylselenocysteine; Se-Methylseleno-L-cysteine. CAS No. 26046-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114245.
Se-(Methyl)selenocysteine (free base)
Se-(Methyl)selenocysteine (free base)
Sarchem Laboratories New Jersey NJ
Se-(Methyl)selenocysteine hydrochloride
Se-(Methyl)selenocysteine hydrochloride is an anticancer agent that inhibits cell cycle proliferation and induces apoptosis. Synonyms: (2R)-2-amino-3-methylselanylpropanoic acid hydrochloride; (R)-2-Amino-3-(methylselanyl)propanoic acid hydrochloride; Se-MSC. Grades: >95%. CAS No. 863394-07-4. Molecular formula: C4H10ClNO2Se. Mole weight: 218.55.
Se-methyl-seleno-L-cysteine
Se-methyl-seleno-L-cysteine. CAS No: 26046-90-2
Sarchem Laboratories New Jersey NJ
Semicarbazide hydrochloride
Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase ( SSAO ). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride. CAS No. 563-41-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0470.
Semicarbazide hydrochloride
Semicarbazide hydrochloride. Group: Biochemicals. Alternative Names: Hydrazinecarboxamide monohydrochloride; Aminourea hydrochloride. Grades: Highly Purified. CAS No. 563-41-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: CH6ClN3O. US Biological Life Sciences.
Worldwide
Semicarbazide hydrochloride
500g Pack Size. Group: Building Blocks, Organics. Formula: CH5N3O · HCl. CAS No. 563-41-7. Prepack ID 12845490-500g. Molecular Weight 111.53. See USA prepack pricing.
Semicarbazide hydrochloride
100g Pack Size. Group: Building Blocks, Organics. Formula: CH5N3O · HCl. CAS No. 563-41-7. Prepack ID 12845490-100g. Molecular Weight 111.53. See USA prepack pricing.
Semilicoisoflavone B
Semilicoisoflavone B. Group: Biochemicals. CAS No. 129280-33-7. Pack Sizes: 5mg. US Biological Life Sciences.
Seminalplasmin is an antibacterial peptide isolated from Bovine Bos taurus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Asp-Glu-Lys-Ala-Ser-Pro-Asp-Lys-His-His-Arg-Phe-Ser-Leu-Ser-Arg-Tyr-Ala-Lys-Leu-Ala-Asn-Arg-Leu-Ala-Asn-Pro-Lys-Leu-Leu-Glu-Thr-Phe-Leu-Ser-Lys-Trp-Ile-Gly-Asp-Arg-Gly-Asn-Arg-Ser-Val. CAS No. 147958-06-3. Molecular formula: C76H123N17O16. Mole weight: 1530.9.
Seminal Vesicles, Ram, Frozen HisTek
Application: Group: Biologicals. Pack Sizes: 250g. US Biological Life Sciences.
Microsomal fraction of ram seminal vesicles. Group: Biologicals. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Semorinemab
Semorinemab (RG 6100) is an anti- Tau humanized IgG4 monoclonal antibody, targets the N-terminal portion of the Tau protein (amino acid residues 6-23). Semorinemab binds with human Tau with a K d value of 3.8 nM. Semorinemab can be used for the research of Alzheimer's Disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 6100; RO7105705; MTAU-9937A. CAS No. 2159141-27-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99399.
Semotiadil
Heterocyclic Organic Compound. Alternative Names: SEMOTIADIL;-2-[2-[3-[[2-(1,3-Benzodioxol-5-yloxy)ethyl]methylamino]propoxy]-5-rnethoxyphenyl]-4-methyl-2H-1,4-benzothiazin-3(4H)-one;DS-4823:SD-3211;(2R)-2α-[2-[3-[[2-(1,3-Benzodioxol-5-yloxy)ethyl]methylamino]propoxy]-5-methoxyphenyl]-4-methyl-2H-1,4-be. CAS No. 116476-13-2. Molecular formula: C29H32N2O6S. Mole weight: 536.646. Catalog: ACM116476132.
Semustine
Semustine is a DNA alkylator , binds to DNA, and acts as a cancer chemotherapeutic agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13909-09-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13747.
Semustine
Semustine is a chemotherapy drug similar to lomustine. Semustine alkylates and cross-links DNA thus exhibits cytotoxicity. Uses: Semustine is an alkylating agent and interstrand dna cross linker. anti-cancer chemotherapeutic agents, which are used in the treatment of different types of cancer such as brain tumors, resistant hodgkin's disease, lung cancer and malignant melanoma. Synonyms: N-(2-Chloroethyl)-N'-(4-methylcyclohexyl)-N-nitrosourea; 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)nitrosourea; Me-CCNU; Methyl Lomustine; Methyl-CCNU; N'-(4-Methylcyclohexyl)-N-(2-chloroethyl)-N-nitrosourea. Grades: ≥95%. CAS No. 13909-09-6. Molecular formula: C10H18ClN3O2. Mole weight: 247.72.
Semustine
Semustine is an alkylating agent and interstrand DNA cross linker. Anti-cancer chemotherapeutic agents, which are used in the treatment of different types of cancer such as brain tumors, resistant HodgkinÂs disease, lung cancer and malignant melanoma. Group: Biochemicals. Grades: Highly Purified. CAS No. 13909-09-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H18ClN3O2, Molecular Weight: 247.72. US Biological Life Sciences.
Worldwide
SEN 12333
SEN 12333. Group: Biochemicals. Grades: Purified. CAS No. 874450-44-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SEN 12333
SEN 12333 is a brain penetrating and orally bioactive α7 nicotinic acetylcholine receptor (nAChR) agonist (EC50 = 1.6 μM, Ki = 260 nM at rat α7 nAChRs) exhibiting neuroprotective property. SEN 12333 also displays functional antagonist activity at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Synonyms: WAY 317538; SEN 12333; WAY317538; SEN12333; WAY-317538; SEN-12333; N-[4-(3-pyridinyl)phenyl]-4-morpholinepentanamide; 5-morpholin-4-yl-N-(4-pyridin-3-ylphenyl)pentanamide. Grades: ≥99% by HPLC. CAS No. 874450-44-9. Molecular formula: C20H25N3O2. Mole weight: 339.43.
SEN 1269
SEN 1269, under the IUPAC name 3-[[5-[3-(dimethylamino)phenoxy]pyrimidin-2-yl]amino]phenol, is a derivative of pyrimidine that inhibits Amyloid-β (Aβ) aggregation and protects neuronal cell lines exposed to Aβ(1-42). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: SEN-1269; SEN 1269; SEN1269; 956128-01-1; 3-(5-(3-(dimethylamino)phenoxy)pyrimidin-2-ylamino)phenol; 3-({5-[3-(dimethylamino)phenoxy]pyrimidin-2-yl}amino)phenol; 3-((5-(3-(Dimethylamino)phenoxy)pyrimidin-2-yl)amino)phenol; SCHEMBL3602388; CHEMBL2386874; CTK5H7888; DTXSID40676566; 4350AF; ZINC49582255; AKOS015850742; AK213225; HE061847; DB-080315; TC-064564; FT-0682533; A11161; I06-2365; 3-[[5-[3-(dimethylamino)phenoxy]-2-pyrimidinyl]amino]phenol; SEN 1269|3-[[5-[3-(Dimethylamino)phenoxy]-2-pyrimidinyl]amino]phenol. CAS No. 956128-01-1. Molecular formula: C18H18N4O2. Mole weight: 322.36.
SEN 1269
SEN 1269. Group: Biochemicals. Grades: Purified. CAS No. 956128-01-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Senaparib
Senaparib (IMP4297) is a highly potent, selective and orally active PARP1/2 inhibitor. Senaparib (IMP4297) exhibits strong antitumor activity in animal models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMP4297; JS109. CAS No. 1401682-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137450.
A flavoprotein. NADH cannot replace NADPH. While pyrrolizidine alkaloids of the senecionine and monocrotaline types are generally good substrates (e.g. senecionine, retrorsine and monocrotaline), the enzyme does not use ester alkaloids lacking an hydroxy group at C-7 (e.g. supinine and phalaenopsine), 1,2-dihydro-alkaloids (e.g. sarracine) or unesterified necine bases (e.g. senkirkine) as substrates. Senecionine N-oxide is used by insects as a chemical defense: senecionine N-oxide is non-toxic, but it is bioactivated to a toxic form by the action of cytochrome P-450 oxidase when absorbed by insectivores. Group: Enzymes. Synonyms: senecionine monooxygenase (N-oxide-forming); SNO. Enzyme Commission Number: EC 1.14.13.101. CAS No. 220581-68-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0700; senecionine N-oxygenase; EC 1.14.13.101; 220581-68-0; senecionine monooxygenase (N-oxide-forming); SNO. Cat No: EXWM-0700.
Seneciphylline
Seneciphylline is a naturally occurring alkaloid that has been identified in the leaves of the plant Senecio longilobus. It is an autophagy inducer and has been shown to potentiate the effects of matrix metalloproteinase (MMP) and to modulate the activity of mitochondrial enzymes. This alkaloid also induces apoptosis in murine sarcoma virus-infected cells. Seneciphylline has been found to be a genotoxic agent, with evidence for its genotoxic activity being observed in various studies. The long-term toxicity and toxicological studies on seneciphylline have not yet been conducted. Group: Other alkaloids. CAS No. 480-81-9. Molecular formula: C18H23NO5. Mole weight: 333.38 g/mol. Canonical SMILES: C/C=C\1/CC (=C)[C@@] (C (=O)OCC2=CCN3[C@H]2[C@@H] (CC3)OC1=O) (C)O. Catalog: ACM480819.
Seneciphylline N-oxide is a model system. It is a quinone that has been shown to be regulated in transcriptional regulation and protein synthesis. It has been used as a sample preparation for tissue culture studies and an analytical method for the detection of monoclonal antibodies. The matrix effect on protein synthesis has been studied under different conditions, including tissue culture and chemical interactions with the drug. The uptake of seneciphylline N-oxide was observed in plant families such as legumes and soybeans, which have polyclonal antibodies that are specific to this drug. Group: Other alkaloids. CAS No. 38710-26-8. Molecular formula: C18H23NO6. Mole weight: 349.38 g/mol. Canonical SMILES: C/C=C/1\CC (=C)[C@@] (C (=O)OCC2=CC[N+]3 ([C@H]2[C@@H] (CC3)OC1=O)[O-]) (C)O. Catalog: ACM38710268.
Senecivernine N-oxide
Senecivernine N-oxide is a metabolite of the alkaloid senecivernine. Senecivernine N-oxide is found in humans and the plant Aspalathus linearis. The analytical method for this compound has been established using LC-MS/MS. The matrix effect, which is the difference in response to chemical compounds due to their different levels of solubility in different matrices, can be controlled by adding an appropriate chemical modifier to the mobile phase. Retronecine, retrorsine, and intermedine are metabolites of senecivernine that have also been identified using LC-MS/MS. Group: Other alkaloids. CAS No. 101687-28-9. Molecular formula: C18H25NO6. Mole weight: 351.39 g/mol. Canonical SMILES: O=C (C1=C)O[C@@]2 (CC[N+]3 ([C@@]2 (C (COC ([C@] (O) ([C@@H] ([C@H]1C)C)C)=O)=CC3)[H])[O-])[H]. Catalog: ACM101687289.
Senegalin
Senegalin is an antibacterial peptide isolated from Kassina senegalensis. It has activity against gram-positive bacteria and fungi. Synonyms: Phe-Leu-Pro-Phe-Leu-Ile-Pro-Ala-Leu-Thr-Ser-Leu-Ile-Ser-Ser-Leu. Grades: >96%. Molecular formula: C375H613N103O119S3. Mole weight: 1732.14.
Senegenin
Senegenin. Group: Biochemicals. Grades: Highly Purified. CAS No. 2469-34-3. Pack Sizes: 20mg. Molecular Formula: C30H45CIO6. US Biological Life Sciences.
Worldwide
Senegenin (Tenuifolic acid)
Senegenin (Tenuifolic acid). Group: Biochemicals. Alternative Names: Tenuifolic acid. Grades: Plant Grade. CAS No. 2469-34-3. Pack Sizes: 20mg. Molecular Formula: C30H45ClO6, Molecular Weight: 537.128. US Biological Life Sciences.
Worldwide
Senexin A
Senexin A is a selective Cell division protein kinase 8 (CDK8) inhibitor with IC50 value of 280 nM. Senexin A can bind to cdk19 in an ATP-competitive manner and it can also inhibit p21-induced transcription. Senexin A may inhibit the activation of tumor-promoting and pro-inflammatory secreted factors in the tumor microenvironment through preventing transcriptional activation of NFκB-induced genes. Uses: Anti-tumor. Synonyms: 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitril. Grades: 98%. CAS No. 1366002-50-7. Molecular formula: C17H14N4. Mole weight: 274.33.
Senfolomycin A
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin E; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-(4-C-acetyl-2,6-dideoxy-3-O-methyl-a-L-xylo-hexopyranosyl)-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-butenyl]-b-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BA. CAS No. 11017-36-0. Molecular formula: C29H36N2O16S. Mole weight: 700.66.
Senfolomycin B
It is produced by the strain of Str. ochrosporus NRRL 3146. It has the effect of anti-Gram-positive bacteria and mycobacterium, and also has the effect of anti-Staphylococcus aureus resistant to penicillin, streptomycin, neomycin, macrolide antibiotics. It also has weaker effect of anti-Gram-negative bacteria. Synonyms: Paulomycin F; 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-(1-hydroxyethyl)-3-O-methyl-α-L-xylo-hexopyranosyl]-4-O-[(2Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (5S)-; Antibiotic LL RA 6950BB. CAS No. 11031-56-4. Molecular formula: C29H38N2O16S. Mole weight: 702.68.
Senicapoc
Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca 2+ -activated K + channel; KCa3.1 ) blocker with an IC 50 of 11 nM. Senicapoc blocks Ca 2+ -induced rubidium flux from human RBCs with an IC 50 value of 11 nM and inhibits RBC dehydration with IC 50 of 30 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICA-17043. CAS No. 289656-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50694.
Senicapoc
Senicapoc, previously called as ICA 17043, is a small organic potent and selective blocker of the Gardos channel which is the calcium-activated potassium channel located on the human RBC, inhibiting the efflux of K+ through this channel. Synonyms: 2,2-bis(4-fluorophenyl)-2-phenylacetamide; bis(4-fluorophenyl)phenylacetamide; ICA 17043; ICA-17043; ICA17043. CAS No. 289656-45-7. Molecular formula: C20H15F2NO. Mole weight: 323.34.
Seniprutug
Seniprutug is an anti- TRBV9 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2484772-72-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990762.
Senkirkine
Senkirkine is a hepatotoxic pyrrolizidine alkaloid. Studies show that Senkirkine has carincogenic activity as it induced chromosomal aberrations in cultured mammalian cells as well as hepatic tumors in rats. Group: Biochemicals. Alternative Names: (1R, 4Z, 6R, 7R)-4-Ethylidene-7-hydroxy-6, 7, 14-trimethyl-2, 9-dioxa-14-azabicyclo[9. 5. 1]heptadec-11-ene-3, 8, 17-trione; 12-Hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione; 2,3,5,7a-Tetrahydro-1,7a-dihydroxy-7-(hydroxymethyl)-4-methyl-1H-pyrrolizinium hydroxide Inner Salt Cyclic Diester with Senecic Acid; [1R-(1R*, 4Z, 6R*, 7R*)]-4-Ethylidene-7-hydroxy-6, 7, 14-trimethyl-2, 9-dioxa-14-azabicyclo[9. 5. 1]heptadec-11-ene-3, 8, 17-trione; NSC 89945; Renardin; Renardine; Senkirkin. Grades: Highly Purified. CAS No. 2318-18-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Senktide
Senktide. Group: Biochemicals. Grades: Purified. CAS No. 106128-89-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Senktide
Senktide is a potent tachykinin NK3 receptor agonist. It exhibits a less potent effect on the NK1 receptor (EC50 = 35 μM) and no effect on the NK2 receptor. Senktide was demonstrated the stimulation of dopamine neurons and the enhancement of dopaminergic function. Synonyms: [Succinyl-Asp6, NMePhe8]-Substance P (6-11); N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-L-methioninamide. Grades: >97%. CAS No. 106128-89-6. Molecular formula: C40H55N7O11S. Mole weight: 842.
Senkyunolide A
Senkyunolide A. Group: Biochemicals. Alternative Names: Sedanenolide; 3-Butyl-4,5-dihydrophthalide; Senkyunolide. Grades: Plant Grade. CAS No. 63038-10-8. Pack Sizes: 20mg. Molecular Formula: C12H16O2, Molecular Weight: 192.253999999999. US Biological Life Sciences.
Worldwide
Senkyunolide H
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 94596-27-7. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
Worldwide
Senkyunolide I
Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Group: Inhibitors. Alternative Names: (3Z,6R,7R)-rel-3-Butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone. CAS No. 94596-28-8. Molecular formula: C12H16O4. Mole weight: 224.25. Appearance: Powder. Purity: 0.98. IUPACName: (3Z,6S,7S)-3-butylidene-6,7-dihydroxy-4,5,6,7-tetrahydro-2-benzofuran-1-one. Canonical SMILES: CCC/C=C\1/C2=C ([C@@H] ([C@H] (CC2)O)O)C (=O)O1. Density: 1.28 g/ml. Catalog: ACM94596288.
Senkyunolide I
Senkyunolide I. Group: Biochemicals. Grades: Plant Grade. CAS No. 94596-28-8. Pack Sizes: 20mg. Molecular Formula: C12H16O4, Molecular Weight: 224.25. US Biological Life Sciences.
Worldwide
Senna Leaf Extract
Senna leaf extract is prepared from a large genus of flowering plant Cassia angustifolia Vahl in the fabaceae family on the tropics. Senna leaf extract have been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components sennoside in senna leaf extract are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides. Group: Others. Mole weight: 862.7391. Senna Leaf Extract; Cassia Angustifolia Vahl. Cat No: EXTC-034.
Senna Leaf P.E. 8% Sennosides UV - Water Soluble
Senna Leaf P.E. 8% Sennosides UV - Water Soluble.
CA, FL & NJ
Senna Leaf Powder
Senna Leaf Powder.
CA, FL & NJ
Sennidin B
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation. Group: Inhibitors. Alternative Names: 9-(2-Carboxy-4,5-dihydroxy-10-oxo-9H-anthracen-9-yl)-4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylic acid. CAS No. 517-44-2. Molecular formula: C30H18O10. Mole weight: 538.46. Appearance: Powder. Purity: 0.98. IUPACName: (9S)-9-[(9R)-2-carboxy-4,5-dihydroxy-10-oxo-9H-anthracen-9-yl]-4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylic acid. Canonical SMILES: C1=CC2=C (C (=C1)O)C (=O)C3=C ([C@@H]2[C@H]4C5=C (C (=CC=C5)O)C (=O)C6=C4C=C (C=C6O)C (=O)O)C=C (C=C3O)C (=O)O. Density: 1.695±0.06 g/ml. Catalog: ACM517442.
Sennoside A
Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia). Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication. Group: Inhibitors. Alternative Names: 4, 4', 10, 10'-Tetrahydroxy-5, 5'-bis(((2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[9, 9'-bianthracene]-2, 2'-dicarboxylic acid. CAS No. 81-27-6. Molecular formula: C42H38O20. Mole weight: 862.75. Appearance: Yellow solid. Purity: 0.98. IUPACName: (9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid. Canonical SMILES: C1=CC2=C (C (=C1)O[C@H]3[C@@H] ([C@H] ([C@@H] ([C@H] (O3)CO)O)O)O)C (=O)C4=C ([C@@H]2[C@@H]5C6=C (C (=CC=C6)O[C@H]7[C@@H] ([C@H] ([C@@H] ([C@H] (O7)CO)O)O)O)C (=O)C8=C5C=C (C=C8O)C (=O)O)C=C (C=C4O)C (=O)O. Density: 1.743±0.06 g/ml. Catalog: ACM81276-1.
Sennoside A
Sennoside A. Group: Biochemicals. Grades: Plant Grade. CAS No. 81-27-6. Pack Sizes: 20mg. Molecular Formula: C42H38O20, Molecular Weight: 862.74. US Biological Life Sciences.
Worldwide
Sennoside A
Sennoside A is an anthraquinone glycoside found in senna ( Cassia angustifolia ). Sennoside A is an HIV-1 inhibitor (IC 50 =3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC 50 s of 1.9 μM and 5.3 μM, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 81-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0365.
Sennoside B
Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-57-4. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0366.