A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles. Administration of luciferase mRNA in SM-102-containing lipid nanoparticles induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development of lipid nanoparticles for delivery of mRNA-based vaccines. Group: Others. Alternative Names: SM-102; SM102; SM 102. CAS No. 2089251-47-6. Molecular formula: C44H87NO5. Mole weight: 710.18. Appearance: Oily liquid. Purity: >98%. IUPACName: heptadecan-9-yl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate. Canonical SMILES: OCCN (CCCCCC (OCCCCCCCCCCC)=O)CCCCCCCC (OC (CCCCCCCC)CCCCCCCC)=O. Catalog: ACM2089251476-3.
SM 16
SM 16 is a potent and selective TGF-β receptor type 1 (TGF-βRI) inhibitor with IC50 value of 64 nM in luciferase assay. SM 16 blocked TGF-beta and activin-induced Smad2/3 phosphorylation and TGF-beta-induced plasminogen activator inhibitor (PAI)-luciferase activity in cells. Synonyms: SM-16; SM16; 4-[4-(1,3-Benzodioxol-5-yl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-2-yl]bicyclo[2.2.2]octane-1-carboxamide. Grades: ≥98% by HPLC. CAS No. 614749-78-9. Molecular formula: C25H26N4O3. Mole weight: 430.5.
SM-164
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein and binds to cIAP-1 and cIAP-2 proteins. It is developed as an anticancer agent. It plays its antitumor roles through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. It binds to cIAP-1 protein containing bothBIR2 and BIR3 domains, cIAP-2 BIR3 protein and XIAP protein containing both BIR2 and BIR3 domains. Synonyms: SM 164; SM164; SM-164. Grades: >98%. CAS No. 957135-43-2. Molecular formula: C62H84N14O6. Mole weight: 1121.42.
SM-164
SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 957135-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15989.
SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC 50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Group: Signaling pathways. CAS No. 2734174-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15989A.
SM 196A
SM 196A is a quinone antibiotic produced by Streptomyces sp. DMS 4769. It exhibits activity against gram-positive bacteria. Synonyms: SM-196A. CAS No. 135635-82-4. Molecular formula: C20H20O5. Mole weight: 340.4.
SM 196B
SM 196B is a quinone antibiotic produced by Streptomyces sp. DMS 4769. Its activity against gram-positive bacteria is more potent than that of SM 196A. It also has anti-Herpes simplex virus activity. Synonyms: SM-196B. CAS No. 135635-83-5. Molecular formula: C20H18O5. Mole weight: 338.4.
SM-21 maleate
SM-21 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155059-42-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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SM-21 maleate
SM-21 maleate is a potent and selective σ2 antagonist that can increase acetylcholine release at central muscarinic synapses. SM-21 is used as a potent analgesic and nootropic agent. Uses: Analgesic and nootropic agent. Synonyms: SM-21 maleate; SM 21 maleate; SM21 maleate; (±)-Tropanyl 2-(4-chlorophenoxy)butanoate maleate. Grades: ≥99% by HPLC. CAS No. 155059-42-0. Molecular formula: C18H24ClNO3.C4H4O4. Mole weight: 453.92.
SM 324405
SM 324405 is a potent TLR7 agonist (EC50 = 50 nM). Synonyms: SM-324405; SM324405; SM 324405; Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate. CAS No. 677773-91-0. Molecular formula: C19H23N5O4. Mole weight: 385.42.
Sm4
Sm4 is a SOX18 inhibitor. Sm4 shows SOX18-DNA binding inhibitory activity. Sm4 selectively affects SOX18 transcriptional output in vitro. Sm4 blocks SoxF transcriptional activity in vivo. Sm4 can be used for cancer metastasis and vascular cancers research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 365542-77-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116940.
SM 406
SM 406. Group: Biochemicals. Alternative Names: (5S, 8S, 10aR) -N- (Diphenylmethyl) decahydro-5-[[ (2S) -2- (methylamino) -1-oxopropyl]amino]-3- (3-methyl-1-oxobutyl) -6-oxo-pyrrolo[1, 2-a][1, 5]diazocine-8-carboxamide; AT 406. Grades: Highly Purified. CAS No. 1071992-99-8. Pack Sizes: 1mg. Molecular Formula: C32H43N5O4, Molecular Weight: 561.71. US Biological Life Sciences.
Worldwide
SM-433
SM-433, a Smac mimetic, function as inhibitor of inhibitor of apoptosis proteins (IAPs). SM-433 exhibits strong binding affinity XIAP BIR3 protein with an IC 50 <1 μM (patent WO2008128171A2) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1071992-81-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-138059.
Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Synonyms: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Molecular formula: C28H27N3O3. Mole weight: 453.542.
Sma I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 25°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated (by using of high concentration t4 dna ligase and 10% peg) and recut. Group: Restriction Enzymes. Purity: 2000U; 10000U. CCC↑GGG GGG↓CCC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sma I gene from Serratia marcescens. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1176RE.
Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. Synonyms: SCPB; Met-asn-tyr-leu-ala-phe-pro-arg-met-NH2. Grades: 98%. CAS No. 84746-43-0. Molecular formula: C52H80N14O11S2. Mole weight: 1141.41.
Small Diameter Ti3C2Tx (MXene) Thin Layer Dispersion Solution
Small gap fullerene-ethyl nipecotate are higher order fullerenes with low HOMO-LUMO gaps. These allotropes of carbon are also known as metallofullerenes. They are kinetically unstable and are considered as insoluble small band gap structures. Uses: Small gap fullerene-ethyl nipecotate are higher order fullerenes with low homo-lumo gaps. these allotropes of carbon are also known as metallofullerenes. they are kinetically unstable and are considered as insoluble small band gap structures. small gap fullerene-ethyl nipecotate can be extracted into organic solvents by a chemical redox processes. Group: Supercapacitorscarbon nano materials organic solar cell (opv) materials. Pack Sizes: 250 mg in glass insert. Molecular formula: 912.81. Mole weight: Linear Formula C60(C8H15NO2)x. 1S/C. OKTJSMMVPCPJKN-UHFFFAOYSA-N. ≥95%.
Small gap fullerenes
Insoluble small gap fullerenes can be extracted into organic solvents by simple chemical redox process. Uses: Small gap fullerenes can be used as doping agents on polyaniline (pani) for organic electronics applications. Group: Supercapacitorscarbon nano materials organic solar cell (opv) materials. Pack Sizes: 1 g in glass bottle. Molecular formula: 912.81. Mole weight: Linear Formula C60(C8H15NO2)x. C=1=C2c3c4C=1c5c6c7c8c9c% 10c% 11c% 12c% 13C% 14=[C]% 10=C% 15c% 16c% 17c% 14c% 18c% 13c% 19c% 20c% 12c% 21c% 11c (c% 22c% 23c% 24c (C2=[C]7% 15% 22) c% 25c3c% 26c% 27c4c% 28c5c (c6% 16) c% 29c% 17c% 30c% 18c% 31c% 19c% 32c% 20c (c% 21% 23) c% 33c% 24c% 34c% 25c% 26c% 35c% 36c% 27c% 28c% 29c% 37c% 30c% 31c% 38c% 32c% 33c% 34c% 35c% 38c% 36% 37) c89. 1S/C. OKTJSMMVPCPJKN-UHFFFAOYSA-N.
Small Intestine Microvascular Endothelial Cells, Human (Frozen)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences.
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Small Intestine Microvascular Endothelial Cells, Human (T-25 flask)
Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences.
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small monomeric GTPase
A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the α-subunit of heterotrimeric G-protein GTPase (EC 3.6.5.1). They are involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). Group: Enzymes. Enzyme Commission Number: EC 3.6.5.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4713; small monomeric GTPase; EC 3.6.5.2. Cat No: EXWM-4713.
Small nuclear ribonucleoprotein Sm D1 (11-19)
Small nuclear ribonucleoprotein Sm D1 (11-19) is a 9-aa peptide. Small nuclear ribonucleoprotein Sm D1 takes a part in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as a component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Synonyms: Sm-D1 (11-19); snRNP core protein D1 (11-19).
Small size monolayer Ti3C2 colloidal aqueous solution
Small size monolayer Ti3C2 colloidal aqueous solution. Uses: Biosensors, antibacterial, drug loading and other life science fields. Group: Mxenes materials. CAS No. 12363-89-2.
Small subunit processome component 20 homolog (626-634)
Small subunit processome component 20 homolog (626-634) is a truncated fragment of Small subunit processome component 20 homolog. It can be used in Ovarian carcinoma research. Synonyms: Novel nucleolar protein 73.
Small tube diameter multi-wall carbon nanotubes epoxy compound
Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane, refrigerated liquid (cryogenic liquid) is a colorless odorless liquid. Flammable. Water insoluble.;Natural gas, refrigerated liquid (cryogenic liquid) appears as a flammable liquefied gaseous mixture of straight chain hydrocarbons, predominately methane.;Natural gas, [compressed] appears as a flammable gaseous mixture of straight chain hydrocarbons, predominately compressed methane.;GasVapor; Liquid;Liquid;COLOURLESS ODOURLESS COMPRESSED OR LIQUEFIED GAS. Uses: By selecting proper dispersant and dispersing process, uniform and stable carbon notube epoxy compound was obtained. carbon notubes can be used in epoxy resin composites, conducting static electricity, strengthening and toughening. Group: Carbon nanotubes epoxy compound. CAS N
Sm-AMP-D1
Sm-AMP-D1 is an antibacterial peptide isolated from the seeds of Stellaria media L. It has activity against fungi. Synonyms: Lys-Ile-Cys-Glu-Arg-Ala-Ser-Gly-Thr-Trp-Lys-Gly-Ile-Cys-Ile-His-Ser-Asn-Asp-Cys-Asn-Asn-Gln-Cys-Val-Lys-Trp-Glu-Asn-Ala-Gly-Ser-Gly-Ser-Cys-His-Tyr-Gln-Phe-Pro-Asn-Tyr-Met-Cys-Phe-Cys-Tyr-Phe-Asn-Cys.
Sm-AMP-D2
Sm-AMP-D2 is an antibacterial peptide isolated from the seeds of Stellaria media L. It has activity against fungi. Synonyms: Lys-Ile-Cys-Glu-Arg-Ala-Ser-Gly-Thr-Trp-Lys-Gly-Ile-Cys-Ile-His-Ser-Asn-Asp-Cys-Asn-Asn-Gln-Cys-Val-Lys-Trp-Glu-Asn-Ala-Gly-Ser-Gly-Ser-Cys-His-Tyr-Gln-Phe-Pro-Asn-Tyr-Met-Cys-Phe-Cys-Tyr-Phe-Asp-Cys.
S-(+)-Manidipine
S-(+)-Manidipine is the (S)-Manidipine enantiomer. Uses: Antihypertensive agents. Synonyms: (4S)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl Methyl Ester; (+)-Manidipine. Grades: > 95%. CAS No. 126451-47-6. Molecular formula: C35H38N4O6. Mole weight: 610.7.
SMANT hydrochloride
SMANT hydrochloride is an inhibitor of Smoothened (Smo) signaling via a unique mechanism. SMANT inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy. Synonyms: N-(4-Bromophenyl)-3,5-dimethyl-1-piperidinepropanamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1177600-74-6. Molecular formula: C16H23BrN2O.HCl. Mole weight: 375.73.
SMANT hydrochloride
SMANT hydrochloride is a Smoothened ( Smo ) signaling inhibitor. SMANT hydrochloride is antagonist of Smo accumulation within the primary cilium (PC). SMANT hydrochloride has an equivalent activity in inhibiting SmoM2 (oncogenic form of Smo) and wild-type Smo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1177600-74-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108508.
Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo:EGFP fusion protein in the primary cilium (IC50 = 1.1um). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1177600-74-6. Pack Sizes: 10mg. US Biological Life Sciences.
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SMAP-34
SMAP-34 is an antibacterial peptide isolated from Ov is aries. It has activity against gram-positive bacteria, gram-negative bacteria. Synonyms: Gly-Leu-Phe-Gly-Arg-Leu-Arg-Asp-Ser-Leu-Gln-Arg-Gly-Gly-Gln-Lys-Ile-Leu-Glu-Lys-Ala-Glu-Arg-Ile-Trp-Cys-Lys-Ile-Lys-Asp-Ile-Phe-Arg-NH2. Grades: >95%.
SMARCA2/4-IN-2
SMARCA2/4-IN-2 is a PROTAC target protein ligand ( Ligands for Target Protein for PROTACs ). SMARCA2/4-IN-2 can be used for synthesis PROTAC SMARCA2/4-degrader-5 (HY-159456) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1339378-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163926.
SMARTEEN
Smarteen is a fine white powder obtained from Ruscus aculeatus roots. It is a natural active ingredient with a purity 92-103% by HPLC. USES: Raw material for cosmetic applications, is suitable for skin care products, for skin preperations. Category: Butcher's broom (Ruscus aculeatus), xymyrsine pungens Bubani, Ruscus flexuosus Mill, Ruscus laxus Sm, Ruscus parasiticus Gueldenst, Ruscus ponticus Woronow.
SMBA 1 is a selelctive and high affinity Bax activator (Ki = 43.3 nM) that binds to the S184 binding pocket and inhibits Bax phosphorylation. SMBA 1 exhibits no affinity for other Bcl-2 family members, including Bcl-2, Bak and Bid. SMBA 1 induces apoptosis in lung cancer cell lines which expresses high levels of Bax. Synonyms: SMBA1; SMBA-1; SMBA 1; NSC-408730; NSC408730; NSC 408730; CYD-1-94; CYD 1 94; CYD194; 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol. Grades: ≥98% by HPLC. CAS No. 906440-37-7. Molecular formula: C20H13NO3. Mole weight: 315.32.
SMBA 1
SMBA 1. Group: Biochemicals. Grades: Purified. CAS No. 906440-37-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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SmbB
SmbB is an antibacterial peptide isolated from Streptococcus mutans GS5. It has activity against gram-positive bacteria. Synonyms: Gly-Thr-Thr-Val-Val-Asn-Ser-Thr-Phe-Ser-Ile-Val-Leu-Gly-Asn-Lys-Gly-Tyr-Ile-Cys-Thr-Val-Thr-Val-Glu-Cys-Met-Arg-Asn-Cys-Ser-Lys.
SMCA
Sodium chloroacetate is a white colored powdered solid. It is soluble in water. It may be toxic ingestion or inhalation. It is used to make weed killers, dyes and pharmaceuticals. Uses: In the manufacturing of CMC,/SCMCIn the manufacturing of betainsIntermediate for pharmaceuticalsIntermediate for pesticide. Group: Inorganic Chemical. Alternative Names: SMCA. Grades: Technical Grade. CAS No. 3926-62-3. Pack Sizes: 25Kg/850Kg PP Bags with Inner liner.
SMCC is a protein crosslinker. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64987-85-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 25 g; 100 g. Product ID: HY-42360.
SMCC-DM1
SMCC-DM1 is a mertansine drug (DM1) with a reactive linker SMCC to make antibody drug conjugate. DM1 (mertansine), a thiol-containing maytansinoid, is a potent microtubule-disrupting agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1228105-51-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C51H66ClN5O16S, Molecular Weight: 1072.60999999999. US Biological Life Sciences.
Worldwide
Smd1
Smd1 is an antibacterial peptide isolated from Stomoxys calcitrans. It has activity against gram-negative bacteria. Synonyms: Ala-Ala-Lys-Pro-Met-Gly-Ile-Thr-Cys-Asp-Leu-Leu-Ser-Leu-Trp-Lys-Val-Gly-His-Ala-Ala-Cys-Ala-Ala-His-Cys-Leu-Val-Leu-Gly-Asp-Val-Gly-Gly-Tyr-Cys-Thr-Lys-Glu-Gly-Leu-Cys-Val-Cys-Lys-Glu.
Smd2
Smd2 is an antibacterial peptide isolated from Stomoxys calcitrans. It has activity against gram-positive bacteria, gram-negative bacteria. Synonyms: Ala-Thr-Cys-Asp-Leu-Leu-Ser-Met-Trp-Asn-Val-Asn-His-Ser-Ala-Cys-Ala-Ala-His-Cys-Leu-Leu-Leu-Gly-Lys-Ser-Gly-Gly-Arg-Cys-Asn-Asp-Asp-Ala-Val-Cys-Val-Cys-Arg-Lys.
SMDC818909
This active molecular is a selective p97 inhibitor. The IC50 value of it decreased with increasing ATP concentration. IC50 value is 26.0 ± 0.9μM in 5μM ATP, 11.5 ± 0.9μM in 5μM ATP, 4.9 ± 0.9 μM in 100 μM ATP. These data indicated that SMDC818909 behaved primarily uncompetitively with the ATP substrate. SMDC818909 represents a novel uncompetitive inhibitor whicn can be applicated as a starting point for drug discovery. Uses: Used as a starting point for drug discovery. Synonyms: SMDC818909; SMDC 818909; SMDC-818909. 3-amino-N-(2-methyl-1H-indol-5-yl)pyrazine-2-carboxamide. Grades: 98%. CAS No. 1147823-21-9. Molecular formula: C14H13N5O. Mole weight: 267.29.
The S-(+) enantiomer of Mecamylamine , a noncompetitive neuronal nicotinic receptor modulator. Group: Biochemicals. Alternative Names: (1R,2S,4S)-. Grades: Highly Purified. CAS No. 107596-30-5. Pack Sizes: 10mg. US Biological Life Sciences.
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SMER18
SMER18 is a small molecule enhancer of rapamycin. It act as a mTOR-independent autophagy inducer. It is a positive regulators of autophagy acting independently of rapamycin. It has additive protective effects on the clearance and toxicity of mutant aggregate-prone proteins in vitro. Uses: Smer18 has additive protective effects on the clearance and toxicity of mutant aggregate-prone proteins. Synonyms: SMER18; SMER 18; SMER-18. Grades: >98 %. CAS No. 944153-47-3. Molecular formula: C15H14ClNO2. Mole weight: 287.74.
SMER28
SMER28 is a small-molecule modulator of autophagy that increases autophagosome synthesis and enhances clearance of aggregate-prone substrates, including those relevant to Huntington's, Parkinson's, and Alzheimer's diseases. It enhances reprogramming of mouse fibroblasts into induced neural stem cell-like cells. Synonyms: N-Allyl-6-bromoquinazolin-4-amine; SMER-28; 6-bromo-N-prop-2-enylquinazolin-4-amine. Grades: >98%. CAS No. 307538-42-7. Molecular formula: C11H10BrN3. Mole weight: 264.12.
SMER28
SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide. Uses: Scientific research. Group: Signaling pathways. CAS No. 307538-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100200.
SMER 28
SMER 28. Group: Biochemicals. Grades: Purified. CAS No. 307538-42-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SMER28 (Small-Molecule Enhancer of Rapamycin-28, 6-Bromo-4-allylaminoquinazoline)
Cell permeable. Acts as a positive regulator of autophagy, acting via mTOR-independent mechanism. SMER28 increases autophagosome synthesis and enhances the clearance of model autophagy substrates such as A53T a-synuclein and mutant huntingtin fragments. It is also protective in Drosophila model of Huntingtons Disease (HD). Group: Biochemicals. Grades: Highly Purified. CAS No. 307538-42-7. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
SMER 3
SMER 3. Group: Biochemicals. Grades: Purified. CAS No. 67200-34-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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SMER 3
SMER 3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30), and also a small molecule enhancer of rapamycin (SMER). SMER 3 directly targets the MET30 subunit and induces the expression of MET genes. SMER 3 inhibits cell proliferation. Synonyms: SMER3; SMER-3; SMER 3; 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one. Grades: ≥98% by HPLC. CAS No. 67200-34-4. Molecular formula: C11H4N4O2. Mole weight: 224.18.
S-Methoprene
S-Methoprene is an insect juvenile hormone analog and effective insecticide that blocks the transition from pupa to adult. S-Methoprene is also a CB(1) receptor ligand and inhibits the binding of the CB1 receptor antagonist [ 3 H]CP-55940 to the CB1 receptor ( IC 50 : 19.31 μM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Methoprene; (7S)-Methoprene. CAS No. 65733-16-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1161A.
S-(+)-Methoprene
(S)-(+)-Methoprene is used as an insect growth regulator. Methoprene is also widely used in flea and tick control products for dogs and cats. Synonyms: [S-(E,E)]-11-Methoxy-3,7,11-trimethyl-2,4-dodecadienoic Acid 1-Methylethyl Ester; (+)-Methoprene; (7S)-Methoprene; Altosid XR Briquets; Altoside CP 10; Altoside CP 2; Diacon II; Extinguish; Precor; S-Methoprene; ZR 2458; d-Methoprene. Grades: > 95%. CAS No. 65733-16-6. Molecular formula: C19H34O3. Mole weight: 310.47.
S-(+)-Methoprene
S-(+)-Methoprene. Group: Biochemicals. Grades: Highly Purified. CAS No. 65733-16-6. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C19H34O3. US Biological Life Sciences.
Worldwide
S-Methyl-3-thioacetaminophen
S-Methyl-3-thioacetaminophen. Group: Biochemicals. Alternative Names: N-[4-Hydroxy-3-(methylthio)phenyl]-acetamide; 3- (Methylthio) acetaminophen; 3- (Methylthio) paracetamol. Grades: Highly Purified. CAS No. 37398-23-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H11NO2S. US Biological Life Sciences.
Worldwide
s-Methyl 4,4,4-trifluoro-3-oxothio-butyr ate,98
Heterocyclic Organic Compound. Alternative Names: S-METHYL 4,4,4-TRIFLUORO-3-OXOTHIO-BUTYR ATE, 98;S-methyl 4,4,4-trifluoro-3-oxothio-butyrate;S-Methyl 3-oxo-4,4,4-trifluorothiobutyrate, S-Methyl 4,4,4-trifluoroacetoacetthioate. CAS No. 118528-85-1. Molecular formula: C5H5F3O2S. Mole weight: 186.1522096. Density: 1.352 g/mL at 25 °C(lit.). Catalog: ACM118528851.
S-methyl-5'-thioadenosine deaminase
The enzyme from Thermotoga maritima also functions as S-adenosylhomocysteine deaminase (EC 3.5.4.28) and has some activity against adenosine. Adenosine 5'-phosphate and S-adenosyl-L-methionine (SAM) are not substrates. Group: Enzymes. Synonyms: MTA deaminase; 5-methylthioadenosine deaminase. Enzyme Commission Number: EC 3.5.4.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4559; S-methyl-5'-thioadenosine deaminase; EC 3.5.4.31; MTA deaminase; 5-methylthioadenosine deaminase. Cat No: EXWM-4559.
S-methyl-5'-thioadenosine phosphorylase
Also acts on 5'-deoxyadenosine and other analogues having 5'-deoxy groups. Group: Enzymes. Synonyms: 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase. Enzyme Commission Number: EC 2.4.2.28. CAS No. 61970-06-7. MTAP. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2655; S-methyl-5'-thioadenosine phosphorylase; EC 2.4.2.28; 61970-06-7; 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase. Cat No: EXWM-2655.
S-methyl-5'-thioadenosine phosphorylase from Human, Recombinant
MTAP expression is crucial for the catabolism of methylthioadenosine, which is a by-product of polyamine biosynthesis in the methionine salvage pathway. Protein expression is decreased by homozygous deletion and promoter hypermethylation. N-terminal gst-tagged 57 kda protein containing amino acids 2-end. Applications: S-methyl-5?-thioadenosine phosphorylase human (mtap) is an enzyme used in cancer research that is deficient in many types of cancer. decreased mtap expression may be used as a potential indicator of disease progression of gastrointestinal stromal tumors. mtap may be a used to develop potential therapeutic strategies for hepat ocellular carcinoma ...CAS No. 61970-06-7. MTAP. Mole weight: 57 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0,100 mM NaCl, 0.05% Tween-20, 10% glycerol,and 3 mM DTT. Source: E. coli. Species: Human. S-methyl-5'-thioadenosine phosphorylase; EC 2.4.2.28; 5'-deoxy-5'-methylthioadenosine phosphorylase; MTA phosphorylase; MeSAdo phosphorylase; MeSAdo/Ado phosphorylase; methylthioadenosine phosphorylase; methylthioadenosine nucleoside phosphorylase; 5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase; S-methyl-5-thioadenosine phosphorylase; S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-α-D-ribosyl-transferase; MTAP. Cat No: NATE-0462.
S-methyl-5'-thioinosine phosphorylase
No activity with S-methyl-5'-thioadenosine. The catabolism of of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31, S-methyl-5'-thioadenosine deaminase) and phosphorolysis to hypoxanthine. Group: Enzymes. Synonyms: MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Enzyme Commission Number: EC 2.4.2.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2673; S-methyl-5'-thioinosine phosphorylase; EC 2.4.2.44; MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Cat No: EXWM-2673.
S-methyl-5-thioribose-1-phosphate isomerase
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. This enzyme participates in methionine metabolism. Group: Enzymes. Synonyms: methylthioribose 1-phosphate isomerase; 1-PMTR isomerase; 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase; 1-phospho-5'-S-methylthioribose isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase. Enzyme Commission Number: EC 5.3.1.23. CAS No. 91608-95-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5462; S-methyl-5-thioribose-1-phosphate isomerase; EC 5.3.1.23; 91608-95-6; methylthioribose 1-phosphate isomerase; 1-PMTR isomerase; 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase; S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase; 1-phospho-5'-S-methylthioribose isomerase; S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase. Cat No: EXWM-5462.