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| Product | Description | |
|---|---|---|
| SKF-82958 hydrobromide | SKF-82958 hydrobromide is a synthetic compound of the benzazepine class that acts as a D1/D5 receptor full agonist. It has characteristic anorectic effects, hyperactivity and self-administration in animals. It also acts as an agonist of ERα with negligible activity at ERβ, making it a subtype-selective estrogen. It could induce PPD, SP and PPE mRNA expression in the intact rat striatum. Uses: Skf-82958 hydrobromide has characteristic anorectic effects, hyperactivity and self-administration in animals. it also acts as an agonist of erα with negligible activity at erβ, making it a subtype-selective estrogen. Synonyms: (±)-SKF-82958 hydrobromide; SKF 82958 hydrobromide; SKF82958 hydrobromide; 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol;Chloro-APB hydrobromide;(±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide;6-Chloro-N-allyl-SKF-38393 hydrobromide. Grades: >98%. CAS No. 80751-65-1. Molecular formula: C19H21BrClNO2. Mole weight: 410.73. |  |
| SKF 83566 hydrobromide | SKF 83566 hydrobromide is a potent and selective dopamine D1-like receptor antagonist (Ki~ 0.56 nM for D1; KB = 2 μM for D2). SKF 83566 is also reported to be an antagonist at the vascular 5-HT2 receptor (Ki = 11 nM). Uses: Adenylyl cyclase inhibitors. Synonyms: SKF 83566 hydrobromide; SKF83566 hydrobromide; SKF-83566 hydrobromide; 8-Bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrobromide. Grades: ≥98% by HPLC. CAS No. 108179-91-5. Molecular formula: C17H18BrNO.HBr. Mole weight: 413.15. | |
| SKF 83822 hydrobromide | SKF 83822 hydrobromide is a selective and high affinity dopamine D1-like receptor agonist (Ki = 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, α1A and α1B receptors, respectively). SKF 83822 stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Synonyms: SKF 83822 hydrobromide; SKF83822 hydrobromide; SKF-83822 hydrobromide; 6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propenyl)-1H-3-benzazepine-7,8-diol hydrobromide; 9-chloro-5-(3-methylphenyl)-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide. Grades: ≥98% by HPLC. CAS No. 74115-10-9. Molecular formula: C20H22ClNO2.HBr. Mole weight: 424.76. | |
| SKF 83822 hydrobromide | SKF 83822 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 74115-10-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SKF 83959 | SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80751-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130344. |  |
| SKF 83959 hydrobromide | SKF 83959 hydrobromide is a dopamine D1-like receptor partial agonist (Ki = 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors, respectively), exhibiting anti-Parkinsonian effects and antagonizing the behavioral effects of cocaine. SKF 83959 also acts as an allosteric modulator of the σ1 receptor via potentiating binding of the σ1 receptor. Synonyms: SKF83959 hydrobromide; SKF-83959 hydrobromide; 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-1H-3-benzazepine-7,8-diol hydrobromide; 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, hydrobromide (1:1); 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-3-methyl-1-(3-methylphenyl)-, monohydrobromide. Grades: ≥98% by HPLC. CAS No. 67287-95-0. Molecular formula: C18H20ClNO2.HBr. Mole weight: 398.73. | |
| SKF 83959 hydrobromide | SKF83959 hydrobromide is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 hydrobromide K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 hydrobromide can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-95-0. Pack Sizes: 5 mg. Product ID: HY-103412. | |
| SKF 83959 hydrobromide | SKF 83959 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-95-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF86002 | SKF86002 is a p38 MAP kinase inhibitor. SKF86002 inhibits IL-1 beta production by affecting at least two distinct steps in the biosynthesis of this cytokine. Group: Inhibitors. Alternative Names: SKF-86002; SKF 86002; SKF86002. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.35. Appearance: Solid powder. Purity: >98%. IUPACName: 6-(4-Fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole. Canonical SMILES: FC1=CC=C (C2=C (C3=CC=NC=C3)N4C (SCC4)=N2)C=C1. Catalog: ACM72873746. |  |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Synonyms: SKF-86002; SKF 86002; SKF86002. 6-(4-fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole; 4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene. Grades: >98%. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.36. | |
| SKF 86002 dihydrochloride | SKF 86002 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 116339-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 86002 dihydrochloride | SKF 86002 dihydrochloride is an inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 μM) with anti-inflammatory activity. SKF 86002 was indicated inhibition of LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). It also inhibits 5-lipoxygenase- and cyclooxygenase-mediated arachidonic acid metabolism in RBL-1 cells (IC50 = 10 and 100 μM, respectively). Synonyms: SKF 86002 dihydrochloride; SKF86002 dihydrochloride; SKF-86002 dihydrochloride; 6-(4-Fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo[2,1-b]thiazole dihydrochloride. Grades: ≥98% by HPLC. CAS No. 116339-68-5. Molecular formula: C16H12FN3S.2HCl. Mole weight: 370.27. | |
| SKF 86466 hydrochloride | SKF 86466 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 86129-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 86466 hydrochloride | SKF 86466 hydrochloride is a potent and selective α2 antagonist at pre- and post-junctional α2-adrenoceptors (Ki = 13 and 17 nM, respectively). SKF 86466 exhibits antihypertensive activity in a rat model. Uses: Adrenergic alpha-antagonists. Synonyms: SKF 86466 hydrochloride; SKF86466 hydrochloride; SKF-86466 hydrochloride; 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride. Grades: ≥98% by HPLC. CAS No. 86129-54-6. Molecular formula: C11H14ClN.HCl. Mole weight: 232.15. | |
| SKF 89976A hydrochloride | Cas No. 85375-15-1. | |
| SKF89976A hydrochloride | SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d,l-SKF89976A hydrochloride. CAS No. 85375-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100228A. | |
| SKF 91488 dihydrochloride | SKF 91488 dihydrochloride is a potent inhibitor of histamine N-methyltransferase with no histamine agonist activity. SKF 91488 is used in the treatment of depression, anxiety and Parkinson's disease. Uses: The treatment of depression, anxiety and parkinson's disease. Synonyms: SKF 91488 dihydrochloride; SKF91488 dihydrochloride; SKF-91488 dihydrochloride; 4-(N,N-Dimethylamino)butylisothiourea dihydrochloride. CAS No. 68941-21-9. Molecular formula: C7H17N3S.2HCl. Mole weight: 248.21. | |
| SKF 91488 dihydrochloride | SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a K i value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homodimaprit dihydrochloride. CAS No. 68941-21-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100967. | |
| SKF 91488 dihydrochloride | SKF 91488 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 68941-21-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Skf 95282 | Heterocyclic Organic Compound. CAS No. 104076-39-3. Molecular formula: C22H27N3OS??·2C4H4O4. Mole weight: 613.68. Purity: >98%. Catalog: ACM104076393. | |
| SKF-96365 | SKF-96365, a store-operated Ca2+ entry inhibitor, has been found to restrain the depolarization of circular smooth muscle caused by acetylcholine and also exhibit antineoplastic activity through leading to cells apoptosis. It has been already discontinued. Uses: Skf-96365 is a store-operated ca2+ entry inhibitor that has been found to restrain the depolarization of circular smooth muscle caused by acetylcholine and also exhibit antineoplastic activity through leading to cells apoptosis. Synonyms: SKF-96365; SKF 96365; SKF96365; 1-[2- (4-Methoxyphenyl) -2-[3- (4-methoxyphenyl) propoxy]ethyl]imidazole, 1-[-(3-(4-Methoxyphenyl)propoxy)-4-methoxyphenethyl]-1H-imidazole hydrochloride. Grades: 95%. CAS No. 130495-35-1. Molecular formula: C22H27ClN2O3. Mole weight: 402.91. | |
| SKF 96365 hydrochloride | SKF 96365 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130495-35-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca 2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130495-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100001. | |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a non-selective TRP Channel blocker. |  |
| SKF 97541 | SKF 97541 is a highly potent GABAB agonist, and also acts as a GABAA-ρ antagonist. SKF 97541 exhibits sedative effects in mammals and has the potential to be used in the treatment of various addictions due to neurochemical imbalances. Uses: Potential treatment of addictions. Synonyms: SKF 97541; SKF97541; SKF-97541; 3-Aminopropyl(methyl)phosphinic acid; 3-Apmpa. CAS No. 127729-35-5. Molecular formula: C4H12NO2P. Mole weight: 137.12. | |
| SKF 97541 | SKF 97541. Group: Biochemicals. Grades: Purified. CAS No. 127729-35-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKI 178 | SKI 178 is a non-lipid sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM) used for the treatment of AML. SKI 178 has been shown to induce CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Uses: Aml treatment. Synonyms: SKI-178; SKI 178; SKI178. N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide. Grades: ≥98% by HPLC. CAS No. 1259484-97-3. Molecular formula: C21H22N4O4. Mole weight: 394.42. | |
| SKI-178 | SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). SKI-178 induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1. SKI-178 is a novel therapeutic agent for the treatment of AML, including multidrug-resistant/recurrent AML subtypes. Group: Inhibitors. Alternative Names: SKI-178; SKI 178; SKI178. CAS No. 1259484-97-3. Molecular formula: C21H22N4O4. Mole weight: 394.43. Appearance: Solid powder. Purity: >98%. IUPACName: N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide. Canonical SMILES: O=C (C1=CC (C2=CC=C (OC)C=C2)=NN1)N/N=C (C3=CC=C (OC)C (OC)=C3)\C. Catalog: ACM1259484973. | |
| SKI-I | SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK) , with an IC 50 of 1.2 μM for ST-hSK. SKI-I also inhibits hERK2 ( IC 50 =11 μM). SKI-I induces apoptosis in tumor cell lines [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 306301-68-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115735. | |
| SKI II | SKI II. Group: Biochemicals. Grades: Purified. CAS No. 312636-16-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKI II | SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822. | |
| SKI II | 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. Synonyms: SphK-I2; SKI-II; SKI II. Sphingosine kinase inhibitor II. Grades: >98%. CAS No. 312636-16-1. Molecular formula: C15H11ClN2OS. Mole weight: 302.78. | |
| SKI-II, Sphingosine Kinase Inhibitor (4- [ [4- (4-Chlorophenyl) -2-thiazolyl] amino] phenol) | Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5uM, with no inhibition against ERK2, PI3-kinase, or PKCa at concentrations up to 60uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 312636-16-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| SKI-I, Sphingosine Kinase Inhibitor (5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide) | Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 306301-68-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Skimmianine | Skimmianine is a flavonol glycoside that belongs to the chemical class of dictamnine. It has been shown in vitro to have anti-cancer properties, specifically against cervical cancer. Skimmianine has been shown to bind to dna, specifically at 5-HT2 receptors, and may have potential uses in treating depression, anxiety, and other neuropsychiatric disorders due to its ability to block serotonin uptake. Skimmianine also inhibits acetate extract from the plant family Apocynaceae, which may be useful in inhibiting tumor growth. Group: Other alkaloids. Alternative Names: 7,8-Dimethoxydictamnine. CAS No. 83-95-4. Molecular formula: C14H13NO4. Mole weight: 259.26 g/mol. Appearance: Powder. Purity: 0.98. IUPACName: 4,7,8-Trimethoxyfuro[2,3-b]quinoline. Canonical SMILES: COC1=C (C2=C (C=C1)C (=C3C=COC3=N2)OC)OC. Density: 1.22 g/ml. Catalog: ACM83954-1. | |
| Skimmianine | Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-95-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2081. | |
| Skimmianine | Skimmianine. Group: Biochemicals. Alternative Names: β-Fagarine; Chloroxylonine; Pentaphylline; 7,8-Dimethoxydictamnine. Grades: Plant Grade. CAS No. 83-95-4. Pack Sizes: 20mg. Molecular Formula: C14H13NO4, Molecular Weight: 259.257. US Biological Life Sciences. | Worldwide |
| Skim Milk | Skim Milk - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Skim Milk Blend | Skim Milk Blend - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. | North America & APAC |
| Skimmin | Skimmin. Group: Biochemicals. Grades: Plant Grade. CAS No. 93-39-0. Pack Sizes: 20mg. Molecular Formula: C15H16O8, Molecular Weight: 324.28. US Biological Life Sciences. | Worldwide |
| SkinBrite-30 | SkinBrite-30 is a water soluble, diamide salt of azelaic acid that improves the technical characteristics for formulation. Azelaic acid itself has very poor water solubility, however, it is found in many grain proteins and is a beneficial component of the skin. Uses: Skin lightening, Sebum control, Moisturization. Group: Skin Care Active Ingredients. INCI Name: Potassium Azeloyl Diglycinate (PAD. CAS Number: 477773-67-4. Category: Azelaic Acid derivatives. |  United States and all of its trading partners.. |
| SkinBrite-99 | SkinBrite-99 is a highly concentrated form of glycolic acid. Glycolic acid is an exfoliant. It revitalizes skin and reduces the appearance of fine lines and wrinkles by removing the outer layer of dead skin and bringing a new layer of skin to the surface. Uses: Anti-wrinkle, Exfoliation, Skin lightening, Anti-acne,. Group: Skin Care Active Ingredients. INCI Name: Glycolic Acid. CAS Number: 79-14-1. | United States and all of its trading partners.. |
| SkinFirm Dipeptide | Two peptides that interact with the most relevant protein structures of the dermal-epidermal junction including laminin, integrin and various collagens. Uses: Skin restoring & anti-aging creams, eye creams, serums, after-sun products, makeup, sunscreens. Group: Skin actives. CAS No. 56-81-5 / 7732-18-5 / 883558-32-5 / 794590-34-4. Appearance: Colorless, slightly viscous solution. Catalog: CI-SC-0688. | |
| SkinLift DPHP | Plant-derived lipid agent consisting of hydroxyproline (natural amino acid essential for skin collagen synthesis) and palmitic acid (natural fatty acid). Has naturally high affinity for skin proteins. Uses: Anti-aging, anti-wrinkle & anti-stretch mark creams & lotions, firming & toning products, moisturizing and lip treatment formulations. Group: Skin actives. CAS No. 41672-81-5. Appearance: White granular powder, faint odor. Catalog: CI-SC-0626. | |
| SkinRenewal Complex | Complex of natural active ingredients consisting of low molecular weight glycosaminoglycans (500-2000 daltons) and polysaccharides from marine sources. Contains yeast extract, algae extract, glucosamine HCI, and urea. Shown to induce exfoliation & skin cell renewal. Uses: Anti-aging & anti-wrinkle creams, aha-free mild exfoliating products, hair care products, makeup. Group: Skin actives. CAS No. 7732-18-5 / 57-13-6 / 66-84-2 / 92128-82-0 / 90046-12-1 / 84604-16-0. Appearance: Clear light yellowish solution. Catalog: CI-SC-0963. | |
| SkinTight AP | High-purity algae extract from micro algae (Nannochloropsis oculata) combined with pullulan, a film-forming natural sugar (glucan) from the fungus Aureobasidium Pullulans. Contains vitamin C & B12 as antioxidants. Uses: Tightening gels, lotions, serums, face masks, lifting products, anti-aging and anti-wrinkle products, hydrating and rejuvenating products. Group: Skin actives. CAS No. 7732-18-5/92128-82-0/9057-02-7. Appearance: Yellow to amber, viscous liquid. Catalog: CI-SC-0972. | |
| SkinTight C-Root | Oligosccarides (sugars) obtained from chicory root (Cichorium intybus). Uses: Tightening lotions and serums, specialty masks, daily moisturizers, make-up formulations. Group: Skin actives. CAS No. 7732-18-5/56-81-5/39300-88-4. Appearance: Colorless, slightly yellow liquid viscous solution. Catalog: CI-SC-0770. | |
| SkinWhite Ascutin | Combination ingredient consisting of two different skin-whitening components for for superior performance. Gluten-free and paraben-free. Uses: All kinds of skin lightening and anti-age spots formulas. anti-aging products. Group: Skin actives. CAS No. 7732-18-5 / 73049-73-7 / 86404-04-8 / 84390-01-8. Appearance: Clear to slightly hazy liquid, light amber to medium brown, may sediment slightly over time. Catalog: CI-SC-0965. | |
| SkinWhite BLE (Bearberry Extract) | Skin lightening agent made from natural arbutin extracted from bearberry leaves (arctostaphylos uva-ursi) and vitamin C (magnesium ascorbyl phosphate). Uses: All kinds of skin-lightening products including lotions, creams, fluids, makeup products. Group: Skin actives. CAS No. 497-76-7/114040-31-2/113170-55-1. Appearance: Clear yellowish liquid. Catalog: CI-SC-0630. | |
| SkinWhite Herb | Different alpine plants combined in a proprietary and synergistic ratio maximizing their activity and producing an even more effective compound. Has an effect on tyrosinase inhibiting mechanism involved in melanin production as found in various studies. Compatible with up to 50% alcohol. Uses: All kinds of skin lightening and anti-age spots formulas. anti-aging products. Group: Skin actives. CAS No. 56-81-5 / 84082-57-5 / 84082-70-2 / 84787-68-8 / 84695-94-3 / 85117-19-7 / 84082-61-1 / 84082-83-7. Appearance: Clear amber liquid. Catalog: CI-SC-0703. | |
| SkinWhite MSH Fluid | Unique skin lightening agent made of natural amino acids with a lipid-residue. Prepared as easy-to-use liquid formula. Uses: All kinds of skin-lightening products including lotions, creams, fluids, makeup products. Group: Skin actives. CAS No. 57-55-6/175357-18-3/68201-46-7. Appearance: pale yellow to light amber, clear to slightly cloudy liquid. Catalog: CI-SC-0711. | |
| SkinWhite NiacinamideLQ | Liquid blend of niacinamide, quinoa and pea extracts to enhances skin glow & radiance. Can minimize the appearance of dark spots & hyperpigmentation over time and supports even skin tone for a more flawless appearance. Uses: Skin creams, anti-aging formulations, face masks, face serums, face gels & toners. Group: Skin actives. CAS No. 7732-18-5 / 98-92-0 / 90082-41-0 / 223749-71-1 / 100-51-6 / 24634-61-5 / 535-32-1. Appearance: Clear amber liquid. Catalog: CI-SC-0973. | |
| SkinWhite Punarnava | Natural plant extract obtained from the roots of punarnava (Boerhaavia diffusa) dissolved in propanediol and water. Uses: Facial lightening treatments, skin lightening body milks, photo-aging repairing treatments, anti-aging treatments, make-up lines and deodorants. Group: Skin actives. CAS No. 504-63-2/7732-18-5. Appearance: Pale brown, transparent liquid, slightly turbid. Catalog: CI-SC-0638. | |
| Skirtboard Rubber | Skirtboard Rubber. Group: Polymers. |  |
| SKI V | SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC 50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC 50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24418-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12895. | |
| SKL 2001 | SKL 2001 is a Wnt/β-catenin signaling pathway agonist that modulates the differentiation of mesenchumal stem cells. It upregulates the β-catenin responsive transcription via increasing the intracellular β-catenin protein level, and inhibits the phosphorylation of β-catenin at residues Ser33/37/Thr41 and Ser45. Synonyms: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II; 5-(furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide. Grades: 99%. CAS No. 909089-13-0. Molecular formula: C14H14N4O3. Mole weight: 286.29. | |
| SKL2001 free base | SKL-2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level. Group: Agonists. Alternative Names: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II. CAS No. 909089-13-0. Molecular formula: C14H14N4O3. Mole weight: 286.29. Appearance: Solid powder. Purity: >98%. IUPACName: 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide. Canonical SMILES: O=C (C1=NOC (C2=CC=CO2)=C1)NCCCN3C=CN=C3. Catalog: ACM909089130. | |
| SKLB1002 | SKLB1002 is a new potent VEGFR2 inhibitor, which could significantly inhibit HUVEC proliferation, migration, invasion, and tube formation. In vivo zebrafish model experiments showed that SKLB1002 remarkably blocked the formation of intersegmental vessels in zebrafish embryos. SKLB1002 inhibits angiogenesis and may be a potential drug candidate in anticancer therapy. Synonyms: SKLB1002; SKLB 1002; SKLB-1002. Grades: 0.98. CAS No. 1225451-84-2. Molecular formula: C13H12N4O2S2. Mole weight: 320.39. | |
| SKLB-1028 | SKLB1028 is a novel Bcr-abl tyrosine kinase inhibitor, Epidermal growth factor inhibitor and Fms-like tyrosine kinase 3 inhibitor originated by CSPC Ouyi Pharmaceutical. Phase-I clinical trials in Acute myeloid leukaemia (Monotherapy, Second-line therapy or greater) in China is on-going. Uses: Acute myeloid leukaemia. Synonyms: SKLB-1028; SKLB 1028; SKLB1028; 9-isopropyl-N2-(4-(4-methylpiperazin-1-yl)phenyl)-N8-(pyridin-3-yl)-9H-purine-2,8-diamine. Grades: 98%. CAS No. 1350544-93-2. Molecular formula: C24H29N9. Mole weight: 443.56. | |
| SKLB-197 | SKLB-197 is a potent and highly selective ATR inhibitor. SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo. In addition, this compound exhibited good pharmacokinetic properties. Group: Inhibitors. Alternative Names: SKLB-197; SKLB 197; SKLB197. CAS No. 2713577-16-1. Molecular formula: C25H24N6O. Mole weight: 424.51. Appearance: Solid powder. Purity: >98%. IUPACName: Quinazoline, 2-(1H-indol-4-yl)-4-[(3R)-3-methyl-4-morpholinyl]-6-(1-methyl-1H-pyrazol-5-yl)-. Canonical SMILES: CN1N=CC=C1C2=CC3=C (N4[C@H] (C)COCC4)N=C (C5=CC=CC6=C5C=CN6)N=C3C=C2. Catalog: ACM2713577161. | |
| SKLB-23bb | SKLB-23bb is an orally bioavailable and selective HDAC6 inhibitor exhibiting microtubule-disrupting ability. Synonyms: HDAC6-IN-1; N-hydroxy-4-[2-methoxy-5-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]butanamide. CAS No. 1815580-06-3. Molecular formula: C21H24N4O4. Mole weight: 396.44. | |
| SKLB610 | SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth factor receptor 2 (FGFR2) and platelet-derived growth factor receptor (PDGFR) at rate of 97%, 65% and 55%, respectively, at concentration of 10μM in biochemical kinase assays. SKLB610 exhibited its antitumor activity as a multi-targeted inhibitor with more potent inhibition of VEGFR2 activity. Its potential to be a candidate of anticancer agent is worth being further investigated. Synonyms: SKLB610; SKLB 610; SKLB-610. Grades: 0.98. CAS No. 1125780-41-7. Molecular formula: C21H16F3N3O3. Mole weight: 415.372. | |
| SKLB610 | SKLB-610 is a multi-target inhibitor of the tyrosine kinases. It is most potent against VEGFR2 and exhibits slightly weaker inhibitor of FGFR2 and PDGFR. Group: Fluorinated apis. CAS No. 1125780-41-7. Molecular formula: C21H16F3N3O3. Mole weight: 415.37. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: N-methyl-4-[4-[[3- (trifluoromethyl) benzoyl]amino]phenoxy]pyridine-2-carboxamide. Catalog: OFC1125780417. | |
| SK-N-SH Transfection Reagent | Transfection Reagent for SKNSH Neuroblastoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6916. |  Nevada, Texas, USA |
| Skp2 Inhibitor C1 | Skp2 Inhibitor C1(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts. Synonyms: MDK-1699; MDK 1699; MDK1699; Skp2 inhibitor C1 and SKPin C1. Grades: >98%. CAS No. 432001-69-9. Molecular formula: C18H13BrN2O4S2. Mole weight: 465.34. | |
| SKPin C1 | SKPin C1. Group: Biochemicals. Grades: Purified. CAS No. 432001-69-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKQ1 | SKQ1, also known as plastoquinonyl decyltriphenyl phosphonium or PDTP, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. Synonyms: SKQ1; SKQ 1; SKQ-1; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide; Visomitin. Grades: 95%. CAS No. 934826-68-3. Molecular formula: C36H42BrO2P. Mole weight: 617.61. | |
| Skullcapflavone II | Skullcapflavone II is derived from Scutellaria baicalensis, inhibitis ovalbumin-induced airway inflammation in a mouse model of asthma. Group: Biochemicals. Grades: Highly Purified. CAS No. 55084-08-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H18O8, Molecular Weight: 374.34. US Biological Life Sciences. | Worldwide |
| Skullcapflavone II | Skullcapflavone II Inhibitor. Uses: Scientific use. Product Category: TN1040. CAS No. 55084-08-7. |  |
| Skullcap Herb Powder (Scutellaria Lateriflora) | Skullcap Herb Powder (Scutellaria Lateriflora). |  CA, FL & NJ |
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