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| Product | Description | |
|---|---|---|
| Sitagliptin N-Phoshate Impurity | Sitagliptin N-Phoshate Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)phosphoramidic acid. Grades: > 95%. CAS No. 1351498-25-3. Molecular formula: C16H16F6N5O4P. Mole weight: 487.29. |  |
| Sitagliptin N-sulfate | Sitagliptin N-sulfate. Group: Biochemicals. Alternative Names: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic acid. Grades: Highly Purified. CAS No. 940002-57-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H15F6N5O4S. US Biological Life Sciences. |  Worldwide |
| Sitagliptin N-Sulfate | Sitagliptin N-Sulfate is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic Acid; (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)sulfamic acid. Grades: > 95%. CAS No. 940002-57-3. Molecular formula: C16H15F6N5O4S. Mole weight: 487.38. | |
| Sitagliptin-N-Sulfate | Sitagliptin-N-Sulfate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 940002-57-3. Molecular Formula: C16H15F6N5O4S. Mole Weight: 487.38. Catalog: APB940002573. |  |
| Sitagliptin N-Sulfate Sodium Salt | Sitagliptin N-Sulfate Sodium Salt is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic Acid Sodium Salt; (R)-(4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)sulfamate, monosodium salt. Grades: >95%. Molecular formula: C16H14F6N5O4NaS. Mole weight: 509.36. | |
| Sitagliptin Oxo impurity | Sitagliptin Oxo impurity is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-7-(3-Amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one; Oxo SLP; Oxo Sitagliptin. Molecular formula: C16H13F6N5O2. Mole weight: 421.30. | |
| sitagliptin phosphate | sitagliptin phosphate. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C7H7F3N4O. Mole Weight: 220.16. Catalog: APB09567. | |
| Sitagliptin phosphate | Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate. CAS No. 654671-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749A. |  |
| Sitagliptin Phosphate | Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate. Grades: Highly Purified. CAS No. 654671-78-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin phosphate monohydrate | Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749B. | |
| Sitagliptin Phosphate Monohydrate | Sitagliptin Phosphate Monohydrate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: MK-0431 phosphate monohydrate; 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate monohydrate. Grades: >98%. CAS No. 654671-77-9. Molecular formula: C16H20F6N5O6P. Mole weight: 523.32. | |
| Sitagliptin Phosphate Monohydrate (7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431) | An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates the insulin release and lowers blood glucose. Group: Biochemicals. Grades: Highly Purified. CAS No. 654671-77-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin Related Compound 1 | Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. Grades: >95%. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32. | |
| Sitagliptin Triazecine Analog | Sitagliptin Triazecine Analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor used in the treatment of diabetes mellitus type 2. Synonyms: 10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione. Grades: > 95%. Molecular formula: C16H13F6N5O2. Mole weight: 421.30. | |
| Sitamaquine tosylate | Sitamaquine tosylate is a dose-dependent and orally bioactive inhibitor of complex II (succinate dehydrogenase or SDH) of the respiratory chain in digitonin-permeabilized promastigotes. Sitamaquine has the potential for the treatment of life-threatening visceral leishmaniasis (VL) caused by Leishmania donovani (EC50 value 19.8 μM for L. donovani promastigotes in vitro). Synonyms: WR6026 tosylate; WR-6026 tosylate; WR 6026 tosylate. Grades: 99%. CAS No. 1019640-33-5. Molecular formula: C21H33N3O.C7H8O3S. Mole weight: 515.71. | |
| Sitaxentan sodium | Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0. Synonyms: TBC-11251; TBC 11251; TBC11251. Grades: >98%. CAS No. 210421-74-2. Molecular formula: C18H14ClN2O6S2.Na. Mole weight: 476.89. | |
| Sitaxsentan | Sitaxsentan, also called as IPI 1040 or TBC 11251, is a potent orally bioactive ET receptor antagonist that has a long duration of action (t1/2, 5-7 hours) and is approximately 6,500-fold more selective as an antagonist for ETA compared with ETB receptors. Synonyms: N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide Sitaxentan Sitaxsentan Thelin 184036-34-8 UNII-J9QH779MEM CHEMBL282724 3-Thiophenesulfonamide, N-(4-chloro-3-methyl-5-isoxazolyl)-2-((6-methyl-1,3-ben. Grades: 95%. CAS No. 184036-34-8. Molecular formula: C18H15ClN2O6S2. Mole weight: 454.90. | |
| Sitaxsentan sodium | Sitaxsentan sodium. Group: Biochemicals. Alternative Names: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide. Grades: Highly Purified. CAS No. 210421-74-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H14ClN2NaO6S2. US Biological Life Sciences. | Worldwide |
| Sitaxsentan sodium | Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist of endothelin A receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI 1040 sodium; TBC11251 sodium. CAS No. 210421-74-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11103. | |
| site-1 protease | Cleaves sterol regulatory element-binding proteins (SREBPs) and thereby initiates a process by which the active fragments of the SREBPs translocate to the nucleus and activate genes controlling the synthesis and uptake of cholesterol and unsaturated fatty acids into the bloodstream. The enzyme also processes pro-brain-derived neurotrophic factor and undergoes autocatalytic activation in the endoplasmic reticulum through sequential cleavages. The enzyme can also process the unfolded protein response stress factor ATF6 at an Arg-His-Lys-Lys? site, and the envelope glycoprotein of the highly infectious Lassa virus and Crimean Congo hemorrhagic fever virus at Arg-Arg-Lys-Lys?. Belongs in... No. 167140-48-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4107; site-1 protease; EC 3.4.21.112; 167140-48-9; mammalian subtilisin/kexin isozyme 1; membrane-bound transcription factor site-1 protease; proprotein convertase SKI-1; proprotein convertase SKI-1/S1PPS1; S1P endopeptidase; S1P protease; site-1 peptidase; site-1 protease; SKI-1; SREBP proteinase; SREBP S1 protease; SREBP-1 proteinase; SREBP-2 proteinase; sterol regulatory element-binding protein proteinase; sterol regulatory element-binding protein site 1 protease; sterol-regulated luminal protease; subtilase SKI-1; subtilase SKI-1/S |  |
| site-specific DNA-methyltransferase (adenine-specific) | This is a large group of enzymes, most of which form so-called 'restriction-modification systems' with nucleases that possess similar site specificity [the nucleases are listed as either EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease)]. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system. Enzyme Commission Number: EC 2.1.1.72. CAS No. 69553-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1974; site-specific DNA-methyltransferase (adenine-specific); EC 2.1.1.72; 69553-52-2; modification methylase; restriction-modification system. Cat No: EXWM-1974. | |
| site-specific DNA-methyltransferase (cytosine-N4-specific) | This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease), form so-called 'restriction-modification systems'. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.113. CAS No. 169592-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1712; site-specific DNA-methyltransferase (cytosine-N4-specific); EC 2.1.1.113; 169592-50-1; modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Cat No: EXWM-1712. | |
| Sitoindoside II | 6-O-oleoyl-sitosteryl-ß-D-glucose. Group: Sterols. Alternative Names: 3-O-[(6'-O-oleoyl)-ß-D-glucopyranosyl] sitosterol 18:1 sitosteryl glucose. CAS No. 53657-29-7. Molecular formula: C53H92O7. Mole weight: 841.293. Purity: >99%. Catalog: ACM53657297. |  |
| Sitolactone | Steroidal Compounds. CAS No. 126784-20-1. Molecular formula: C13H18O3. Mole weight: 222.28. Purity: 95%+. Catalog: ACM126784201. | |
| Sitostanol-5,6,22,23-d4 | Labeled sitostanol. Found in many plant sources, the compound inhibits the absorption of cholesterol and may inhibit the synthesis of cholesterol in the liver. Group: 2h labeled compounds. Alternative Names: Stigmastanol-d4. CAS No. 150044-25-0. Molecular formula: C29D4H48O. Mole weight: 420.75. Appearance: Solid. Catalog: ACM150044250. | |
| Sitostenone | Steroids. CAS No. 1058-61-3. Molecular formula: C29H48O. Mole weight: 412.7. Appearance: Cryst. Purity: 0.98. IUPACName: (8S,9S,10R,13R,14S)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one. Canonical SMILES: CCC (CCC (C)C1CCC2C1 (CCC3C2CCC4=CC (=O)CCC34C)C)C (C)C. Catalog: ACM1058613. | |
| Sitosterol | Sitosterol Inhibitor. Uses: Scientific use. Product Category: T2966. CAS No. 83-46-5. |  |
| Sitosterol, β- | Sitosterol, β-. Group: Biochemicals. CAS No. 83-46-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Sitosterol-d7 | Sitosterol-d7. Group: Others. Purity: >99%. Mole weight: 421.75. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; Sitosterol-d7; (24-Ethyl)-heptadeuteriostigmast-5-en-3ss-ol. Cat No: FLBZ-078. | |
| Sitravatinib | Sitravatinib / MGCD516 / MG516 is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth. MGCD516 treatment resulted in significant blockade of phosphorylation of potential driver RTKs and induced potent anti-proliferative effects in vitro. MGCD516 treatment of tumor xenografts in vivo resulted in significant suppression of tumor growth. Group: Fluorinated apis. Alternative Names: MGCD516. CAS No. 1123837-84-2. Molecular formula: C33H29F2N5O4S. Mole weight: 629.68. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 1-N'-[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]pyridin-2-yl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide. Catalog: OFC1123837842. | |
| Sitravatinib | Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively [1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD516; MG-516. CAS No. 1123837-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16961. | |
| Sitravatinib | Sitravatinib, a new inhibitor of tyrosine kinase, has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. It is still under a phase II trial for Non small cell lung cancer. IC50: 3980 nmol/L. Uses: Sitravatinib has been studied to have effective in inhibiting tyrosine kinases receptors involved in driving sarcoma cell growth. it is still under a phase ii trial for non small cell lung cancer. Synonyms: MGCD516; MGCD-516; MGCD 516; MG516; MG 516; MG-516; Sitravatinib. Grades: 98%. CAS No. 1123837-84-2. Molecular formula: C33H29F2N5O4S. Mole weight: 629.68. | |
| Sivelestat | Sivelestat is a competitive human neutrophil elastase (HNE) inhibitor (IC50 = 44 nM, Ki=0.2 μM). It also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse (IC50 = 19 to 49 nM). However, it does not inhibit trypsin, thrombin, plasmin, plasma kallikrein, pancreas kallikrein, chymotrypsin and cathepsin G even at 100 μM. In in-vivo studies, it suppressed lung hemorrhage in hamster (ID50 = 82 μg/kg) by intratracheal administration and increase of skin capillary permeability in guinea pig (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase. Synonyms: EI546; EI 546; EI-546; LY544349; LY 544349; LY-544349; ONO5046; ONO-5046; ONO 5046. Grades: >98%. CAS No. 127373-66-4. Molecular formula: C20H22N2O7S. Mole weight: 434.46. | |
| Sivelestat sodium | Sivelestat sodium(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse. Synonyms: Sivelestat sodium. Grades: >98%. CAS No. 150374-95-1. Molecular formula: C20H21N2NaO7S. Mole weight: 456.44. | |
| Sivelestat sodium | Sivelestat sodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150374-95-1. Molecular Formula: C20H21N2NaO7S. Mole Weight: 456.45. Catalog: APB150374951. | |
| Sivelestat sodium salt | Sivelestat sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 150374-95-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sivelestat sodium tetrahydrate | Sivelestat is a competitive human neutrophil elastase (HNE) inhibitor (IC50 = 44 nM, Ki=0.2 μM). It also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse (IC50 = 19 to 49 nM). However, it does not inhibit trypsin, thrombin, plasmin, plasma kallikrein, pancreas kallikrein, chymotrypsin and cathepsin G even at 100 μM. In in-vivo studies, it suppressed lung hemorrhage in hamster (ID50 = 82 μg/kg) by intratracheal administration and increase of skin capillary permeability in guinea pig (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase. Uses: Serine proteinase inhibitors. Synonyms: EI546 sodium tetrahydrate; EI 546 sodium tetrahydrate; EI-546 sodium tetrahydrate; LY544349 sodium tetrahydrate; LY 544349 sodium tetrahydrate; LY-544349 sodium tetrahydrate; ONO5046 sodium tetrahydrate; ONO 5046 sodium tetrahydrate; ONO-5046 sodium tetrahydrate. Grades: >98%. CAS No. 201677-61-4. Molecular formula: C20H29N2NaO11S. Mole weight: 528.51. | |
| Sivifene | Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-007. CAS No. 2675-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14801. | |
| Sivifene | Sivifene gel is the phenylhydrazone 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone formulated as a topical agent with immunomodulating and potential antineoplastic activities. Applied topically as a gel, sivifene may stimulate a local immune response against human papillomavirus (HPV)-induced cervical intraepithelial neoplasia. Synonyms: A 007; A007; A-007; 4-[[2-(2,4-dinitrophenyl)hydrazinyl]-(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one; 4,4'-Dihydroxybenzophenone 2,4-dinitrophenylhydrazone. CAS No. 2675-35-6. Molecular formula: C19H14N4O6. Mole weight: 394.34. | |
| Sivopixant | Sivopixant is a potent and selective P2X3 receptor antagonist. Sivopixant has the potential for the treatment of neuropathic pain and cough. Synonyms: S 600918; S-600918; S600918. CAS No. 2414285-40-6. Molecular formula: C25H22ClN5O5. Mole weight: 507.93. | |
| Siyry | A Kb-restricted epitope peptide. CAS No. 178561-37-0. Molecular formula: C50H71N11O13. Mole weight: 1034.1600000000001. | |
| SIYRY acetate | A Kb-restricted epitope peptide. Molecular formula: C52H75N11O15. Mole weight: 1094.25. | |
| SJ000291942 | SJ000291942 is a bone morphogenetic protein (BMP) signaling pathway activator. It activates BMP4 in C33A-2D2 human cervical cancer clone reporter cells (EC50 = ≤1 μM). Synonyms: CBMicro_010677; Oprea1_383864; SCHEMBL20620014; ZINC444226; BCP29880. Grades: 98%. CAS No. 425613-09-8. Molecular formula: C16H15FN2O4. Mole weight: 318.3. | |
| SJ 172550 | SJ 172550 is a MDMX inhibitor (EC50 = 2.3 μM), controls the biological activity of MDMX. Uses: Mdmx inhibitor. Synonyms: MDMX Inhibitor II; SJ-172550; SJ 172550; SJ172550Methyl {2-chloro-6-ethoxy-4-[(E)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl]phenoxy}acetate;2-[2-chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-acetic acid, methyl est. Grades: ≥98 %. CAS No. 431979-47-4. Molecular formula: C22H21ClN2O5. Mole weight: 428.9. | |
| SJ 172550 | SJ 172550. Group: Biochemicals. Grades: Purified. CAS No. 431979-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SJ6986 | SJ6986 is a Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degrader from a Focused Library of Cereblon Modulator. Group: Others. Alternative Names: SJ6986; SJ-6986; SJ 6986. CAS No. 2765625-93-0. Molecular formula: C20H14F3N3O7S. Mole weight: 497.4. Appearance: Solid powder. Purity: >98%. IUPACName: N- (2- (2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-5-yl)-2- (trifluoromethoxy)benzenesulfonamide. Canonical SMILES: O=S (C1=CC=CC=C1OC (F) (F)F) (NC2=CC3=C (C (N (C (CC4)C (NC4=O)=O)C3=O)=O)C=C2)=O. Catalog: ACM2765625930. | |
| SJB2-043 | SJB2-043 is one of analogs/derivatives of C527, which is a novel and potent USP1 (ubiquitin-specific protease 1) inhibitor. It inhibited the Ub-VS labeling of a limited number of endogenous DUB enzymes and inhibited the labeling of USP1 with Ub-VS in a dose dependent manner. Synonyms: SJB2-043; SJB2043; SJB2 043. Grades: >98%. CAS No. 63388-44-3. Molecular formula: C17H9NO3. Mole weight: 275.26. | |
| SJF-0628 | SJF-0628 (compound 512) is a PROTAC RAF degrader. SJF-0628 induces targeted degradation of BRAF mutants ( DC 50 : 5.4 nM, 4.64 nM, 15.5 nM, 2.11 nM, 63.9 nM for BRAF V600E, V600K, G464V, G469A, K601E respectively). SJF-0628 has anti-tumor activity. SJF-0628 can be used for research of disorders that result from aggregation or accumulation of RAF, or the constitutive activation of RAF [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413035-41-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136420. | |
| SJF-1521 | SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 contains the EGFR inhibitor lapatinib (HY-50898). SJF-1521 can induce EGFR degradation in OVCAR8 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-40-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131865. | |
| SJG-136 | SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA. SJG-136 has potent antitumor activity. Synonyms: SJG 136; SJG136; SJG-136; SP-2001; SP2001; SP 2001; BN 2629; BN2629; BN-2629; SG2000; SG 2000; SG-2000; NSC 694501; NSC694501; NSC-694501. Grades: >98.0%. CAS No. 232931-57-6. Molecular formula: C31H32N4O6. Mole weight: 556.61. | |
| SK1-IN-1 | SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor (IC50 = 58 nM). Synonyms: (2S,3S)-N-[(1S)-1-[4-[5-(2-cyclopentylethyl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-3-hydroxypyrrolidine-2-carboxamide. CAS No. 1218816-71-7. Molecular formula: C22H30N4O3. Mole weight: 398.5. | |
| SK 216 | SK 216 is an orally available plasminogen activator inhibitor-1 (PAI-1) inhibitor. It inhibits VEGF-induced migration and tube formation in HUVECs, and suppresses angiogenesis in the tumor. SK 216 also attenuates TGF-β dependent epithelial-mesenchymal transition and fibroblast to myofibroblast differentiation in vitro. Synonyms: SK-216; SK 216; SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor. 2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]propanedioic acid disodium salt. Grades: ≥98% by HPLC. CAS No. 654080-03-2. Molecular formula: C29H29NO6Na2. Mole weight: 533.52. | |
| SK609 hydrochloride | SK609 hydrochloride is a dopamine D3 receptor (D3R) selective agonist with an EC 50 of 1109 nM. SK609 hydrochloride has the potential for parkinson research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092797-77-7. Pack Sizes: 5 mg. Product ID: HY-117059. | |
| SKA-121 | SKA-121 is a positive-gating modulator of intermediate-conductance calcium-activated potassium channels (IKCa1/KCa3.1). It also activates KCa2.2 and KCa2.3 channels. In blood pressure telemetry experiments, SKA-121 (100 mg/kg i.p.) significantly lowered mean arterial blood pressure in normotensive and hypertensive wild-type but not in KCa3.1-/- mice. Synonyms: SKA121; SKA 121; 5-methylnaphtho[2,1-d]oxazol-2-amine. Grades: ≥98%. CAS No. 1820708-73-3. Molecular formula: C12H10N2O. Mole weight: 198.2. | |
| SKA 31 | SKA 31 is a KCa3.1 and KCa2 channel activator (EC50 = 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2, respectively). SKA 31b has been shown to potentiate acetylcholine-induced EDHF-type dilations of mouse carotid arteries and reduce blood pressure levels in normotensive and hypertensive mice. Synonyms: SKA-31; SKA 31; SKA31; Naphtho[1,2-d]thiazol-2-ylamine; 2-Amino-beta-naphthothiazole; 2-Aminonaphthiazole. Grades: ≥99% by HPLC. CAS No. 40172-65-4. Molecular formula: C11H8N2S. Mole weight: 200.26. | |
| SKA 31 | SKA 31. Group: Biochemicals. Grades: Purified. CAS No. 40172-65-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKA-31 | SKA-31 is a potent potassium channel activator with EC 50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1 , KCa2.2 , KCa2.1 and KCa2.3 , respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40172-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111655. | |
| Skatole | Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors ( AhR ) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methylindole; 3-Methyl-1H-indole. CAS No. 83-34-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W007355. | |
| Skeletal Nickel Catalyst slurry in Water | Skeletal Nickel Catalyst slurry in Water. Group: Biochemicals. Alternative Names: Raney Nickel slurry in Water. Grades: Highly Purified. CAS No. 7440-02-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Skepinone-L | Skepinone-L is a selective p38α-MAPK inhibitor with IC50 of 5 nM. Grades: >98%. CAS No. 1221485-83-1. Molecular formula: C24H21F2NO4. Mole weight: 425.42. | |
| SKF 38393 hydrobromide | SKF 38393 hydrobromide is a selective dopamine D1-like receptor partial agonist (Ki = 1, ~ 0.5, ~ 150, ~ 5000 and ~ 1000 nM for D1, D5, D2, D3 and D4 receptors, respectively). Synonyms: SKF 38393 hydrobromide; SKF38393 hydrobromide; SKF-38393 hydrobromide; (±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrobromide; 5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide. Grades: ≥99% by HPLC. CAS No. 20012-10-6. Molecular formula: C16H17NO2.HBr. Mole weight: 336.23. | |
| SKF 38393 hydrobromide | SKF 38393 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 20012-10-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| SKF-38393 hydrochloride | SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist. It has stimulant and anorectic effects. Synonyms: SKF-38393; SKF 38393; SKF38393; SKF-38,393; SKF 38,393; SKF38,393; SKF-38393 HCl; SKF-38393 hydrochloride. Grades: 98%. CAS No. 62717-42-4. Molecular formula: C16H18ClNO2. Mole weight: 291.78. | |
| SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
| SKF 77434 hydrobromide | SKF 77434 hydrobromide is a selective dopamine D1-like receptor partial agonist (IC50 = 19.7 and 2425 nM for binding to D1-like and D2-like receptors, respectively). Synonyms: SKF 77434 hydrobromide; SKF77434 hydrobromide; SKF-77434 hydrobromide; SKF-77434 HBr; SKF 77434 HBr; SKF77434 HBr; N-Allyl-SKF38393 HBr; 2,3,4,5-Tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol hydrobromide; N-Allyl-(+/-)-SKF-38393 hydrobromide. Grades: ≥99% by HPLC. CAS No. 300561-58-4. Molecular formula: C19H21NO2.HBr. Mole weight: 376.29. | |
| SKF 81297 | SKF 81297 is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71636-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12236A. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12236. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide is a selective dopamine D1-like receptor agonist. Synonyms: SKF 81297 hydrobromide; SKF81297 hydrobromide; SKF-81297 hydrobromide; (±)-6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide; 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide. Grades: ≥98% by HPLC. CAS No. 67287-39-2. Molecular formula: C16H16ClNO2.HBr. Mole weight: 370.67. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF81367 | SKF81367, an impurity of Cefuroxime, is a cephalosporin antibiotic. Synonyms: SKF81367; SKF 81367; SKF-81367; (6R,7R)-3-(acetyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefuracetime; Cefuracetima; Cefuracetimum. CAS No. 39685-31-9. Molecular formula: C17H17N3O8S. Mole weight: 423.4. | |
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