A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| SLF | SLF is a cell-permeable analog of FK-506, an immunosuppressant with high affinity for FK-506 binding protein 12 (FKBP12). SLF binds tightly to FKBP but lacks the ability to inhibit calcineurin. Alternative Names: SLF Exclusive; Synthetic Ligand of FKBP. Grades: ≥98%. CAS No. 195513-96-3. Molecular formula: C30H40N2O6. Mole weight: 524.66. |  |
| SLF1081851 | SLF1081851 is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 plays a key role in development and immune system[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2763730-97-6. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149004. |  |
| SLF80821178 | SLF80821178 is a potent and orally active inhibitor of Sphingosine-1-Phosphate Transporter (Spns2). SLF80821178 inhibits S1P release with an IC50 of 51 nM in HeLa cells and a T1/2 of 2.4 h in mouse[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2764877-61-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162655. | |
| SLF-amido-C2-COOH | SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF). SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PROTAC FKBP12-binding moiety 1. CAS No. 1092369-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107452. | |
| Slicon Oxide Hollow Micro Powder | Slicon Oxide Hollow Micro Powder. Purity: >99%. |  |
| SLIGKV-NH2 | SLIGKV-NH2. Group: Biochemicals. Grades: Purified. CAS No. 190383-13-2. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| SLIGRL-NH2 | SLIGRL-NH2. Group: Biochemicals. Grades: Purified. CAS No. 171436-38-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| SLIGRL-NH2 | SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Protease-Activated Receptor-2 Activating Peptide. CAS No. 171436-38-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1308. | |
| S-linalool synthase | Requires Mn2+ or Mg2+ for activity. Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the enzyme from the flower Clarkia breweri. Unlike many other monoterpene synthases, only a single product, (3S)-linalool, is formed. Group: Enzymes. Synonyms: LIS; Lis; 3S-linalool synthase. Enzyme Commission Number: EC 4.2.3.25. CAS No. 160477-81-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5182; S-linalool synthase; EC 4.2.3.25; 160477-81-6; LIS; Lis; 3S-linalool synthase. Cat No: EXWM-5182. |  |
| Slingshot inhibitor D3 | Slingshot inhibitor D3 is a potent, selective, reversible and competitive inhibitor of Slingshot. The IC50 value for Slingshot 1 is 3 μM and the Ki value for Slingshot 2 is 3.9 μM. Slingshot inhibitor D3 has similar inhibitory activities toward both Slingshot 1 and Slingshot 2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1715076-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124366. | |
| Slippery Elm Bark P.E. 4:1 (Gluten free) | Slippery Elm Bark P.E. 4:1 (Gluten free). |  CA, FL & NJ |
| Slippery Elm Bark (Ulmus Rubra) American | Slippery Elm Bark (Ulmus Rubra) American. | CA, FL & NJ |
| Slippery Elm Inner Bark | Slippery Elm Inner Bark. | CA, FL & NJ |
| Sliver Selenide (Ag2Se) | Sliver Selenide (Ag2Se). Alternative Names: Sliver Selenide Powder, Ag2Se Powder, disilver selenide; silver(I) selenide; silver selenide. Purity: 99.999%. | |
| Sliver Sulfide (Ag2S) | Sliver Sulfide (Ag2S). Alternative Names: Sliver Sulfide Powder, Ag2S Powder, disilver sulphide; silver(I) sulphide; argentite; disilver sulfide; silver sulfide; silver sulphide; silver(I) sulfide. Purity: 99.999%. | |
| Sliver Telluride (Ag2Te) | Sliver Telluride (Ag2Te). Alternative Names: Sliver Telluride Powder, Ag2Te Powder, disilver telluride; silver(I) telluride; silver telluride. Purity: 99.999%. | |
| SLK/STK10-IN-1 | SLK/STK10-IN-1 is a potent and selective inhibitor of SLK and STK10 with antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 264210-49-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132868. | |
| SLLK, Control Peptide for TSP1 Inhibitor | SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). Uses: Scientific research. Category: Signaling pathways. CAS No. 2918768-29-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0301. | |
| SLLK, Control Peptide for TSP1 Inhibitor | SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). C-terminus is amidated. Alternative Names: H-Ser-Leu-Leu-Lys-OH. CAS No. 464924-27-4. Molecular formula: C21H41N5O6. Mole weight: 459.59. | |
| SLLK, Control Peptide for TSP1 Inhibitor (TFA) | SLLK, Control Peptide for TSP1 Inhibitor (TFA) is a control peptide for LSKL, which is a Thrombospondin (TSP-1) inhibitor. Molecular formula: C23H42F3N5O8. Mole weight: 573.6. | |
| SLLK-NH2, Control Peptide for TSP1 Inhibitor | SLLK-NH2, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine). Alternative Names: SLLK, Control Peptide for TSP1 Inhibitor; H-Ser-Leu-Leu-Lys-NH2; L-seryl-L-leucyl-L-leucyl-L-lysinamide; SLLK-NH2. Grades: ≥95%. CAS No. 2918768-29-1. Molecular formula: C21H42N6O5. Mole weight: 458.60. | |
| SLLK-NH2, Control Peptide for TSP1 Inhibitor acetate | SLLK-NH2, Control Peptide for TSP1 Inhibitor acetate is a control peptide for LSKL (leucine-serine-lysine-leucine). Alternative Names: H-Ser-Leu-Leu-Lys-NH2.CH3CO2H; L-seryl-L-leucyl-L-leucyl-L-lysinamide acetic acid; SLLK-NH2.CH3CO2H; SLLK, Control Peptide for TSP1 Inhibitor acetate. Grades: ≥95%. CAS No. 2918768-30-4. Molecular formula: C23H46N6O7. Mole weight: 518.66. | |
| SLP120701 HCl | The hydrochloride salt form of SLP120701, an oxadiazol derivative, has been found to be a Sphk inhibitor and could probably be useful in studies of some cancer, fibrosis, and sickle cell diseases. Uses: The hydrochloride salt form of slp120701 has been found to be a sphk inhibitor and could probably be useful in studies of some cancer, fibrosis, and sickle cell diseases. Alternative Names: (S)-2-(3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboximidamide hydrochloride; SLP120701; SLP-120701; SLP120701. Grades: 98%. CAS No. 1449768-46-0. Molecular formula: C20H30ClN5O. Mole weight: 391.94. | |
| SLR080811 HCl | The hydrochloride salt form of SLR080811, an oxadiazol derivative, has been found to be a SphK inhibitor and could probably be useful in studies of some cancer, fibrosis, and sickle cell diseases. Uses: Slr080811 hcl has been found to be a sphk inhibitor and could probably be useful in studies of some cancer, fibrosis, and sickle cell diseases. Alternative Names: SLR080811 HCl; SLR 080811 HCl; SLR-080811 HCl; SLR080811 hydrochloride; SLR 080811 HCl; 1-Pyrrolidinecarboximidamide, 2-[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]-, hydrochloride. Grades: 98%. CAS No. 1449768-36-8. Molecular formula: C21H32ClN5O. Mole weight: 369.50. | |
| Slu-PP-1072 | SLU-PP-1072 is a dual ERRα/γ inverse agonist that inhibits the warburg effect and induces apoptosis in prostate cancer cells. Grades: >98%. Molecular formula: C18H12N2O3S. Mole weight: 336.37. | |
| SLU-PP-332 | SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303760-60-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-155673. | |
| SLV-2436 | SLV-2436 is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50s of 10.8 nM and 5.4 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SEL201-88; SEL-201. CAS No. 2095704-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112113. | |
| Slv319 | Slv319 is a potent antagonist of CB1 recceptor (Ki = 7.8 nM) used for the treatment of neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction and gastrointestinal disorders, as well as inhibits CP 55,940-induced hypotension and WIN 55,212-2-induced hypothermia in vivo. Alternative Names: Slv319; Slv 319; Slv-319; 3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-1H-pyrazole-1-carboximidamide; CHEMBL158784. Grades: 98%. CAS No. 362519-49-1. Molecular formula: C23H20Cl2N4O2S. Mole weight: 487.399. | |
| SLV 320 | SLV 320. Group: Biochemicals. Grades: Purified. CAS No. 251945-92-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SM-102 | SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089251-47-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-134541. | |
| SM-102 | An ionizable amino lipid used as a key excipient for forming lipid nanoparticles (LNPs). Grades: Pharmaceutical grade. Product ID: PE-0708. |  |
| SM-102 | SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles which is used in the Moderna COVID-19 vaccine. Alternative Names: 1-Octylnonyl 8-((2-hydroxyethyl)(6-oxo-6-(undecyloxy)hexyl)amino)octanoate. Grades: 95%. CAS No. 2089251-47-6. Molecular formula: C44H87NO5. Mole weight: 710.16. | |
| SM-102 (GMP Like) | SM-102 (GMP Like) is SM-102 (HY-134541) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2089251-47-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134541GL. | |
| SM102 LNP-Cap 1 EGFP mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is capped with the CAP 1 structure. It is only for research purposes. Group: Lipid nanoparticle. |  |
| SM102 LNP-Cap 1 EGFP mRNA (5-moU) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is capped with the CAP 1 structure and modified with 5-methoxyuridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Cap 1 EGFP mRNA (m1Ψ) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is capped with the CAP 1 structure and modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Cap 1 Fluc mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating Firefly Luciferase mRNA. Firefly Luciferase mRNA, a fluorescence reporter, encodes an enzyme that catalyzes the oxidation of luciferin to oxyluciferin, producing bioluminescence. The loaded Firefly Luciferase mRNA is capped with the CAP 1 structure. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Cap 1 Fluc mRNA (m1Ψ) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating Firefly Luciferase mRNA. Firefly Luciferase mRNA, a fluorescence reporter, encodes an enzyme that catalyzes the oxidation of luciferin to oxyluciferin, producing bioluminescence. The loaded Firefly Luciferase mRNA is capped with the CAP 1 structure and modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Cap 1 OVA mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating OVA mRNA. OVA(ovalbumin) is the predominant glycoprotein in egg whites and is known for its immunogenic properties, making it an ideal model antigen for studying immune responses. The loaded OVA mRNA is capped with the CAP 1 structure. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-EGFP mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-EGFP mRNA (5-moU) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is modified with 5-methoxyuridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-EGFP mRNA (m1Ψ) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating EGFP mRNA. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Empty | This product is a empty LNP prepared with SM102 as the ionizable lipid and can be used as a negative control to determine the optimal mRNA delivery formulation. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Fluc mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating Firefly Luciferase mRNA. Firefly Luciferase mRNA, a fluorescence reporter, encodes an enzyme that catalyzes the oxidation of luciferin to oxyluciferin, producing bioluminescence. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-Fluc mRNA (m1Ψ) | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating Firefly Luciferase mRNA. Firefly Luciferase mRNA, a fluorescence reporter, encodes an enzyme that catalyzes the oxidation of luciferin to oxyluciferin, producing bioluminescence. The loaded Firefly Luciferase mRNA is modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM102 LNP-GFP mRNA | This product is a LNP prepared with ionizable lipid (SM102), helper lipid, cholesterol and PEGylated lipid, encapsulating GFP mRNA. The GFP mRNA encodes the green fluorescent protein (GFP), a widely used marker for monitoring gene expression and transfection efficiency. It exhibits an excitation wavelength of 480 nm and emission at 510 nm. It is only for research purposes. Group: Lipid nanoparticle. | |
| SM-1295 | SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with Kd values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1562375-46-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124181. | |
| SM 16 | SM 16 is a ALK5/ALK4 kinase inhibitor with Kis of 10 and 1.5 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 614749-78-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111482. | |
| SM-164 | SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein and binds to cIAP-1 and cIAP-2 proteins. It is developed as an anticancer agent. It plays its antitumor roles through inducing degradation of cellular inhibitor of apoptosis protein (cIAP)-1/2, antagonizing X-linked inhibitor of apoptosis protein (XIAP) and inducing TNFα-dependent apoptosis in tumor cells. It binds to cIAP-1 protein containing bothBIR2 and BIR3 domains, cIAP-2 BIR3 protein and XIAP protein containing both BIR2 and BIR3 domains. Alternative Names: SM 164; SM164; SM-164. Grades: >98%. CAS No. 957135-43-2. Molecular formula: C62H84N14O6. Mole weight: 1121.42. | |
| SM-164 | SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Category: Signaling pathways. CAS No. 957135-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15989. | |
| SM-164 | SM-164 Inhibitor. Uses: Scientific use. Product Category: T12932L. CAS No. 957135-43-2. |  |
| SM-164 hydrochloride | SM-164 hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP. Uses: Scientific research. Category: Signaling pathways. CAS No. 2734174-02-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15989A. | |
| SM1-71 | SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2088179-99-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136848. | |
| SM 196A | SM 196A is a quinone antibiotic produced by Streptomyces sp. DMS 4769. It exhibits activity against gram-positive bacteria. Alternative Names: SM-196A. CAS No. 135635-82-4. Molecular formula: C20H20O5. Mole weight: 340.4. | |
| SM 196B | SM 196B is a quinone antibiotic produced by Streptomyces sp. DMS 4769. Its activity against gram-positive bacteria is more potent than that of SM 196A. It also has anti-Herpes simplex virus activity. Alternative Names: SM-196B. CAS No. 135635-83-5. Molecular formula: C20H18O5. Mole weight: 338.4. | |
| SM-21 maleate | SM-21 maleate. Group: Biochemicals. Grades: Purified. CAS No. 155059-42-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sm2O3 nanopowder | Sm2O3 nanopowder. Purity: 99.5% (REO). | |
| SM-360320 | SM-360320 (CL-087) is a potent, orally active TLR7 agonist. SM-360320 is a immuno-modulator and exerts an antitumor effect. SM-360320 can act in synergy with DNA vaccines leading to an enhanced Th1 antibody response[1]. SM-360320 can inhibit HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to its IFN-mediated activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CL-087. CAS No. 226907-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125390. | |
| Sm4 | Sm4 is a selective and orally active SOX18 inhibitor. Sm4 inhibits SOX18-DNA binding (IC50 = 97.5 μM); Sm4 disrupts the SOX18-RBPJ protein-protein interaction (IC50 = 42.3 μM). Sm4 blocks SOX18 DNA binding, disrupts multiple SOX18 protein-protein interactions with RBPJ, DDX1, DDX17, ILF3, SOX7 and STAT1, modulates SOX18 chromatin binding dynamics. Sm4 exerts anti - angiogenic and anti - lymphangiogenic effects, reduces tumor vascular density, triggers vascular defects in zebrafish, prolongs survival in mouse metastatic cancer models. Sm4 can be used for the research of breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 365542-77-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116940. | |
| Smac-N7 Peptide | Smac-N7 Peptide. Alternative Names: H-AVPIAQK-OH; H-ALA-VAL-PRO-ILE-ALA-GLN-LYS-OH; AVPIAQK; SMAC-N7 PEPTIDE; SMAC N7 PROTEIN; SMAC PROTEIN (1-7) (HUMAN, MOUSE). Grades: 95%. CAS No. 401913-57-3. Molecular formula: C33H59N9O9. | |
| Smad2/3 Antibody [M18H19] | Mothers against decapentaplegic homolog 3, MAD homolog 3, Mothers against DPP homolog 3, Mad3, JV15-2, SMAD 3, Smad3, hSMAD3, hMAD-3, MADH3, SMAD family member 3, Mothers against decapentaplegic homolog 2, MAD homolog 2, JV18-1, hMAD-2, SMAD 2, Smad2, hSMAD2, Mothers against DPP homolog 2, Mad-related protein 2, SMAD family member 2. Group: Antibodies. Alternative Names: hSMAD2, hSMAD3. Pack Sizes: 20ul. Product ID: F0363. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| Smad3 Antibody [J9N13] | Smad3 Antibody [J9N13]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0364. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Smad3 Inhibitor, SIS3 | Smad3 Inhibitor, SIS 3 is an inhibitor of SMAD3, which is a receptor-regulated intracellular protein that functions downstream of TGF-β as well as activin receptors and mediates their signaling. It plays an important role in cell proliferation, apoptosis, differentiation and formation of extracellular matrix. It is a cell-permeable pyrrolopyridine compound that selectively inhibits TGF-β1-dependent Smad3 phosphorylation and Smad3-mediated cellular signaling. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. Alternative Names: 1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one. CAS No. 1009104-85-1. Molecular formula: C28H27N3O3. Mole weight: 453.542. | |
| Sma I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 25°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated (by using of high concentration t4 dna ligase and 10% peg) and recut. Group: Restriction Enzymes. Purity: 2000U; 10000U. CCC↑GGG GGG↓CCC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sma I gene from Serratia marcescens. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1176RE. | |
| Small cardioactive peptide B | Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. Alternative Names: SCPB; Met-asn-tyr-leu-ala-phe-pro-arg-met-NH2. Grades: 98%. CAS No. 84746-43-0. Molecular formula: C52H80N14O11S2. Mole weight: 1141.41. | |
| Small Diameter Ti3C2Tx (MXene) Thin Layer Dispersion Solution | Small Diameter Ti3C2Tx (MXene) Thin Layer Dispersion Solution. CAS No. 12363-89-2. | |
| Small gap fullerene-ethyl nipecotate | Small gap fullerene-ethyl nipecotate are higher order fullerenes with low HOMO-LUMO gaps. These allotropes of carbon are also known as metallofullerenes. They are kinetically unstable and are considered as insoluble small band gap structures. Molecular formula: Linear Formula C60(C8H15NO2)x. Mole weight: 912.81. Purity: ≥95%. InChI: 1S/C. | |
| Small gap fullerenes | Insoluble small gap fullerenes can be extracted into organic solvents by simple chemical redox process. Molecular formula: Linear Formula C60(C8H15NO2)x. Mole weight: 912.81. SMILES: C=1=C2c3c4C=1c5c6c7c8c9c%10c%11c%12c%13C%14=[C]%10=C%15c%16c%17c%14c%18c%13c%19c%20c%12c%21c%11c(c%22c%23c%24c(C2=[C]7%15%22)c%25c3c%26c%27c4c%28c5c(c6%16)c%29c%17c%30c%18c%31c%19c%32c%20c(c%21%23)c%33c%24c%34c%25c%26c%35c%36c%27c%28c%29c%37c%30c%31c%38c%32c%33c%34c%35c%38c%36%37)c89. InChI: 1S/C. | |
| small monomeric GTPase | A family of about 50 enzymes with a molecular mass of 21 kDa that are distantly related to the α-subunit of heterotrimeric G-protein GTPase (EC 3.6.5.1). They are involved in cell-growth regulation (Ras subfamily), membrane vesicle traffic and uncoating (Rab and ARF subfamilies), nuclear protein import (Ran subfamily) and organization of the cytoskeleton (Rho and Rac subfamilies). Group: Enzymes. Enzyme Commission Number: EC 3.6.5.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4713; small monomeric GTPase; EC 3.6.5.2. Cat No: EXWM-4713. | |
| Small nuclear ribonucleoprotein Sm D1 (11-19) | Small nuclear ribonucleoprotein Sm D1 (11-19) is a 9-aa peptide. Small nuclear ribonucleoprotein Sm D1 takes a part in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as a component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Alternative Names: Sm-D1 (11-19); snRNP core protein D1 (11-19). | |
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