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| Product | Description | |
|---|---|---|
| Sitaxsentan sodium | Sitaxsentan sodium. Group: Biochemicals. Alternative Names: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide. Grades: Highly Purified. CAS No. 210421-74-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H14ClN2NaO6S2. US Biological Life Sciences. |  Worldwide |
| site-1 protease | Cleaves sterol regulatory element-binding proteins (SREBPs) and thereby initiates a process by which the active fragments of the SREBPs translocate to the nucleus and activate genes controlling the synthesis and uptake of cholesterol and unsaturated fatty acids into the bloodstream. The enzyme also processes pro-brain-derived neurotrophic factor and undergoes autocatalytic activation in the endoplasmic reticulum through sequential cleavages. The enzyme can also process the unfolded protein response stress factor ATF6 at an Arg-His-Lys-Lys? site, and the envelope glycoprotein of the highly infectious Lassa virus and Crimean Congo hemorrhagic fever virus at Arg-Arg-Lys-Lys?. Belongs in... No. 167140-48-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4107; site-1 protease; EC 3.4.21.112; 167140-48-9; mammalian subtilisin/kexin isozyme 1; membrane-bound transcription factor site-1 protease; proprotein convertase SKI-1; proprotein convertase SKI-1/S1PPS1; S1P endopeptidase; S1P protease; site-1 peptidase; site-1 protease; SKI-1; SREBP proteinase; SREBP S1 protease; SREBP-1 proteinase; SREBP-2 proteinase; sterol regulatory element-binding protein proteinase; sterol regulatory element-binding protein site 1 protease; sterol-regulated luminal protease; subtilase SKI-1; subtilase SKI-1/S |  |
| site-specific DNA-methyltransferase (adenine-specific) | This is a large group of enzymes, most of which form so-called 'restriction-modification systems' with nucleases that possess similar site specificity [the nucleases are listed as either EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease)]. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system. Enzyme Commission Number: EC 2.1.1.72. CAS No. 69553-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1974; site-specific DNA-methyltransferase (adenine-specific); EC 2.1.1.72; 69553-52-2; modification methylase; restriction-modification system. Cat No: EXWM-1974. | |
| site-specific DNA-methyltransferase (cytosine-N4-specific) | This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease), form so-called 'restriction-modification systems'. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.113. CAS No. 169592-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1712; site-specific DNA-methyltransferase (cytosine-N4-specific); EC 2.1.1.113; 169592-50-1; modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Cat No: EXWM-1712. | |
| Sitoindoside I | Sitoindoside I. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-naphthalen-2-ylamino-1H-pyrimidine-2,4-dione. Appearance: Powder. CAS No. 18749-71-8. Molecular formula: C51H90O7. Mole weight: 815.3. Purity: 0.98. IUPACName: [(2R,3S,4S,5R,6R)-6-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methyl hexadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC1C(C(C(C(O1)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5C(C)CCC(CC)C(C)C)C)C)O)O)O. Product ID: ACM18749718. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Sitolactone | Sitolactone. Uses: Designed for use in research and industrial production. Product Category: Steroidal Compounds. CAS No. 126784-20-1. Molecular formula: C13H18O3. Mole weight: 222.28. Purity: 95%+. Product ID: ACM126784201. Alfa Chemistry ISO 9001:2015 Certified. | |
| Sitostenone | Sitostenone is isolated from the roots of Xanthium sibiricum. Sitostenone has antioxidant activity and can be used in the treatment of androgen-dependent diseases, especially benign prostatic hyperplasia. Synonyms: Stigmast-4-en-3-one; (24R)-24-Ethylcholest-4-en-3-one; (24R)-Stigmast-4-en-3-one; 4-En-3-stigmastone; NSC 49082; β-Rosasterol oxide; β-Sitost-4-en-3-one; β-Sitostenone; Δ4-Sitosterol-3-one; beta-sitostenone. Grade: >98%. CAS No. 1058-61-3. Molecular formula: C29H48O. Mole weight: 412.69. |  |
| Sitosterol | Sitosterol Inhibitor. Uses: Scientific use. Product Category: T2966. CAS No. 83-46-5. |  |
| Sitosterol, β- | Sitosterol, β-. Group: Biochemicals. CAS No. 83-46-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Sitosterol-d7 | Sitosterol-d7. Group: Others. Purity: >99%. Mole weight: 421.75. Stability: 6 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; bioactive lipids; fluorescent lipids; singnal transduction; cell pathways; Sitosterol-d7; (24-Ethyl)-heptadeuteriostigmast-5-en-3ss-ol. Cat No: FLBZ-078. | |
| Sitravatinib | Sitravatinib (MGCD516) is an orally bioavailable receptor tyrosine kinase (RTK) inhibitor with IC 50 s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT3, DDR2, DDR1, TRKA, TRKB, respectively [1]. Sitravatinib shows potent single-agent antitumor efficacy and enhances the activity of PD-1 blockade through promoting an antitumor immune microenvironment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD516; MG-516. CAS No. 1123837-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16961. |  |
| SiTrzCz2 | SiTrzCz2. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9'-(6-(3-(Triphenylsilyl)phenyl)-1,3,5-triazine-2,4-diyl)bis(9H-carbazole). Product Category: Organic Light Emitting Diode (OLED). CAS No. 2422045-58-5. Molecular formula: C51H35N5Si. Mole weight: 745.94 g/mol. Product ID: ACM2422045585. Alfa Chemistry ISO 9001:2015 Certified. | |
| Sivelestat | Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EI546; LY544349; ONO5046. CAS No. 127373-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17443. | |
| Sivelestat sodium | Sivelestat sodium. Uses: For analytical and research use. Group: Impurity standards. CAS No. 150374-95-1. Molecular formula: C20H21N2NaO7S. Mole weight: 456.45. Catalog: APB150374951. |  |
| Sivelestat sodium salt | Sivelestat sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 150374-95-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Sivelestat sodium salt hydrate | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Sivifene | Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-007. CAS No. 2675-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14801. | |
| Siyry | A Kb-restricted epitope peptide. CAS No. 178561-37-0. Molecular formula: C50H71N11O13. Mole weight: 1034.1600000000001. | |
| SIYRY acetate | A Kb-restricted epitope peptide. Molecular formula: C52H75N11O15. Mole weight: 1094.25. | |
| SJ000025081 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SJ000291942 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SJ 172550 | SJ 172550. Group: Biochemicals. Grades: Purified. CAS No. 431979-47-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SJ-172550 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SJ3149 | SJ3149 is a selective and potent molecular glue degrader of CK1? protein with broad antiproliferative activity. SJ3149 can be used in cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026986-17-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160444. | |
| SJ6986 | SJ6986 is a potent, selective and orally active GSPT1/2 Molecular Glue degrader, with a DC50 of 2.1 nM (Dmax 99%) for GSPT1[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765625-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132199. | |
| SJ6986 | SJ6986 is a Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degrader from a Focused Library of Cereblon Modulator. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SJ6986; SJ-6986; SJ 6986. Product Category: Others. Appearance: Solid powder. CAS No. 2765625-93-0. Molecular formula: C20H14F3N3O7S. Mole weight: 497.4. Purity: >98%. IUPACName: N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)-2-(trifluoromethoxy)benzenesulfonamide. Canonical SMILES: O=S(C1=CC=CC=C1OC(F)(F)F)(NC2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)=O. Product ID: ACM2765625930. Alfa Chemistry ISO 9001:2015 Certified. | |
| SJ988497 | SJ988497 is a PROTAC JAK2 degrader. SJ988497 potently inhibits CRLF2-rearranged (CRLF2r) cell proliferation and degrades the CRBN neosubstrate GSPT1. SJ988497 consists of a Ruxolitinib (HY-50856) derivative, linker, and CRBN ligand Pomalidomide. SJ988497 can be used in the research of acute lymphoblastic leukemia (ALL)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2595365-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151902. | |
| SJF-0628 | SJF-0628 (compound 512) is a PROTAC RAF degrader. SJF-0628 induces targeted degradation of BRAF mutants ( DC 50 : 5.4 nM, 4.64 nM, 15.5 nM, 2.11 nM, 63.9 nM for BRAF V600E, V600K, G464V, G469A, K601E respectively). SJF-0628 has anti-tumor activity. SJF-0628 can be used for research of disorders that result from aggregation or accumulation of RAF, or the constitutive activation of RAF [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413035-41-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136420. | |
| SJF-1521 | SJF-1521 is a selective EGFR PROTAC degrader. SJF-1521 contains the EGFR inhibitor lapatinib (HY-50898). SJF-1521 can induce EGFR degradation in OVCAR8 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-40-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131865. | |
| SJF-8240 | SJF-8240 (PROTAC 7) is a proteolysis targeting chimera (PROTAC) degrader. SJF-8240 induces polyubiquitination of c-Met and inhibits the proliferation of GTL16 cells (IC50=66.7 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-68-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123961. | |
| SK-216 | SK-216 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that acts as an anti-metastatic agent for human osteosarcoma and inhibits lung metastasis of human osteosarcoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 654080-03-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122714. | |
| SK-216 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SK-575 | SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2523016-96-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139156. | |
| SK609 hydrochloride | SK609 hydrochloride is a dopamine D3 receptor (D3R) selective agonist with an EC 50 of 1109 nM. SK609 hydrochloride has the potential for parkinson research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092797-77-7. Pack Sizes: 5 mg. Product ID: HY-117059. | |
| SK609 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKA-121 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| SKA 31 | SKA 31. Group: Biochemicals. Grades: Purified. CAS No. 40172-65-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKA-31 | SKA-31 is a potent potassium channel activator with EC 50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1 , KCa2.2 , KCa2.1 and KCa2.3 , respectively. SKA-31 potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40172-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111655. | |
| SKA-31 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Skatole | Skatole (3-methylindole) is a heterocyclic compound naturally found in the feces of vertebrates and can be found in certain plants. Skatole can be produced by intestinal bacteria, inducing apoptosis of intestinal epithelial cells through activating aryl hydrocarbon receptors ( AhR ) and p38. Skatole has been used in specific products of the perfume industry or as a flavor additive in ice cream [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methylindole; 3-Methyl-1H-indole. CAS No. 83-34-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W007355. | |
| Skeletal Nickel Catalyst slurry in Water | Skeletal Nickel Catalyst slurry in Water. Group: Biochemicals. Alternative Names: Raney Nickel slurry in Water. Grades: Highly Purified. CAS No. 7440-02-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| Skepinone-L | Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBS3830. CAS No. 1221485-83-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15300. | |
| SKF 38393 hydrobromide | SKF 38393 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 20012-10-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| SKF 38393 hydrochloride | SKF 38393 hydrochloride is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-SKF-38393 hydrochloride; SKF-38393A. CAS No. 62717-42-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12520A. | |
| SKF-525A, Hydrochloride - CAS 62-68-0 | Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Group: Fluorescence/luminescence spectroscopy. | |
| SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
| SKF 81297 | SKF 81297 is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71636-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12236A. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12236. | |
| SKF 81297 hydrobromide | SKF 81297 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 83822 hydrobromide | SKF 83822 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 74115-10-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 83959 | SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80751-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-130344. | |
| SKF 83959 hydrobromide | SKF83959 hydrobromide is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 hydrobromide K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 hydrobromide is a potent allosteric modulator of sigma (σ)-1 receptor. SKF83959 hydrobromide belongs to benzazepine family and has improvements on cognitive dysfunction. SKF83959 hydrobromide can be used for the research of Alzheimer's disease and depression [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67287-95-0. Pack Sizes: 5 mg. Product ID: HY-103412. | |
| SKF 83959 hydrobromide | SKF 83959 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 67287-95-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-83959 hydrobromide | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF86002 | SKF86002 is a p38 MAP kinase inhibitor. SKF86002 inhibits IL-1 beta production by affecting at least two distinct steps in the biosynthesis of this cytokine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF-86002; SKF 86002; SKF86002. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.35. Purity: >98%. IUPACName: 6-(4-Fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole. Canonical SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)N4C(SCC4)=N2)C=C1. Product ID: ACM72873746. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF-86002 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF-86002 - CAS 72873-74-6 | A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). Group: Fluorescence/luminescence spectroscopy. | |
| SKF 86002 dihydrochloride | SKF 86002 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 116339-68-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF 86466 hydrochloride | SKF 86466 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 86129-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-89145 hydrobromide | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF89976A | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A; SKF 89976A; SKF-89976A. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-15-1. Molecular formula: C22H25NO2. Mole weight: 335.45. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O. Product ID: ACM85375151-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF-89976A | >98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF89976A HCl | SKF89976A is a potent GABA uptake inhibitor, which is selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). SKF89976A inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). It is able to pass the blood-brain barrier after systemic administration and is active in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKF89976A HCl; SKF 89976A; SKF-89976A; SKF89976A hydrochloride. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 85375-85-5. Molecular formula: C22H26ClNO2. Mole weight: 371.9. Purity: >98%. IUPACName: 1-(4,4-diphenylbut-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride. Canonical SMILES: O=C(C1CN(CC/C=C(C2=CC=CC=C2)/C3=CC=CC=C3)CCC1)O.[H]Cl. Product ID: ACM85375855-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| SKF89976A hydrochloride | SKF89976A hydrochloride is a selective GABA transporter ( GAT-1 ) inhibitor with IC 50 s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d,l-SKF89976A hydrochloride. CAS No. 85375-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100228A. | |
| SKF 91488 dihydrochloride | SKF 91488 (Homodimaprit) dihydrochloride is a potent and noncompetitive histamine N-methyltransferase inhibitor with a K i value of 0.9 microM. SKF 91488 dihydrochloride inhibits the methylation of labeled histamine in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homodimaprit dihydrochloride. CAS No. 68941-21-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100967. | |
| SKF 91488 dihydrochloride | SKF 91488 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 68941-21-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-96365 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| SKF 96365 hydrochloride | SKF 96365 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130495-35-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a potent TRP channel blocker and a store-operated Ca 2+ entry (SOCE) inhibitor. SKF-96365 hydrochloride significantly inhibits hERG, hKCNQ1/hKCNE1, hKir2.1 and hKv4.3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF-96365 hydrochloride exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130495-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100001. | |
| SKF-96365 hydrochloride | SKF-96365 hydrochloride is a non-selective TRP Channel blocker. |  |
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