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| Product | Description | |
|---|---|---|
| Sitagliptin Impurity 29 | Sitagliptin Impurity 29. Uses: For analytical and research use. CAS No. 1334244-28-8. Molecular formula: C16H16F5N5O. Mole weight: 389.33. Catalog: APB1334244288. |  |
| Sitagliptin Impurity 30 | Sitagliptin Impurity 30. Uses: For analytical and research use. CAS No. 486460-21-3. Molecular formula: C6H7F3N4. Mole weight: 192.14. Catalog: APB486460213. | |
| Sitagliptin Impurity 31 | Sitagliptin Impurity 31. Uses: For analytical and research use. CAS No. 763105-70-0. Molecular formula: C6H9F3N4O. Mole weight: 210.16. Catalog: APB763105700. | |
| Sitagliptin Impurity 32 | Sitagliptin Impurity 32. Uses: For analytical and research use. CAS No. 723286-98-4. Molecular formula: C4H2ClF3N2O. Mole weight: 186.52. Catalog: APB723286984. | |
| Sitagliptin Impurity 33 | Sitagliptin Impurity 33. Uses: For analytical and research use. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32. Catalog: APB331763667. | |
| Sitagliptin Impurity 34 | Sitagliptin Impurity 34. Uses: For analytical and research use. CAS No. 218609-00-8. Molecular formula: C15H20FNO4. Mole weight: 297.32. Catalog: APB218609008. | |
| Sitagliptin Impurity 35 | Sitagliptin Impurity 35. Uses: For analytical and research use. CAS No. 486459-98-7. Molecular formula: C15H19F2NO4. Mole weight: 315.32. Catalog: APB486459987. | |
| Sitagliptin Impurity 36 | Sitagliptin Impurity 36. Uses: For analytical and research use. CAS No. 922178-94-7. Molecular formula: C15H18F3NO4. Mole weight: 333.31. Catalog: APB922178947. | |
| Sitagliptin Impurity 37 | Sitagliptin Impurity 37. Uses: For analytical and research use. CAS No. 881995-69-3. Molecular formula: C11H12F3NO2. Mole weight: 247.22. Catalog: APB881995693. | |
| Sitagliptin Impurity 38 | Sitagliptin Impurity 38. Uses: For analytical and research use. CAS No. 1803026-54-1. Molecular formula: C16H12F6N4O. Mole weight: 390.28. Catalog: APB1803026541. | |
| Sitagliptin Impurity 39 | Sitagliptin Impurity 39. Uses: For analytical and research use. CAS No. 218608-98-1. Molecular formula: C15H20FNO4. Mole weight: 297.32. Catalog: APB218608981. | |
| Sitagliptin Impurity 40 | Sitagliptin Impurity 40. Uses: For analytical and research use. CAS No. 269396-59-0. Molecular formula: C15H19F2NO4. Mole weight: 315.32. Catalog: APB269396590. | |
| Sitagliptin Impurity 40 HCl | Sitagliptin Impurity 40 HCl is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: methyl (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate, hydrochloride (1:1); (R)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride; Methyl (R)-beta-Amino-2,4,5-F3-benzenebutanoate HCl. CAS No. 1374985-05-3. Molecular formula: C11H12F3NO2.HCl. Mole weight: 283.67. |  |
| Sitagliptin Impurity 42 | Sitagliptin Impurity 42. Uses: For analytical and research use. CAS No. 1803026-58-5. Molecular formula: C16H12F6N4O. Mole weight: 390.29. Catalog: APB1803026585. | |
| Sitagliptin Impurity 43 | Sitagliptin Impurity 43. Uses: For analytical and research use. CAS No. 898543-70-9. Molecular formula: C32H25F12N9O2. Mole weight: 795.59. Catalog: APB898543709. | |
| Sitagliptin Impurity 44 | Sitagliptin Impurity 44. Uses: For analytical and research use. CAS No. 1620129-74-9. Molecular formula: C15H18F3NO4. Mole weight: 333.31. Catalog: APB1620129749. | |
| Sitagliptin Impurity 45 | Sitagliptin Impurity 45. Uses: For analytical and research use. CAS No. 1271773-97-7. Molecular formula: C15H19F2NO4. Mole weight: 315.32. Catalog: APB1271773977. | |
| Sitagliptin Impurity 46 | Sitagliptin Impurity 46. Uses: For analytical and research use. CAS No. 1234321-81-3. Molecular formula: C13H12F3NO3. Mole weight: 287.24. Catalog: APB1234321813. | |
| Sitagliptin Impurity 47 | Sitagliptin Impurity 47. Uses: For analytical and research use. CAS No. 849832-73-1. Molecular formula: C6H9F3N4O. Mole weight: 210.16. Catalog: APB849832731. | |
| Sitagliptin Impurity 48 | Sitagliptin Impurity 48. Uses: For analytical and research use. CAS No. 1608491-98-0. Molecular formula: C22H24F6N4O2. Mole weight: 490.45. Catalog: APB1608491980. | |
| Sitagliptin Impurity 49 | Sitagliptin Impurity 49. Uses: For analytical and research use. Molecular formula: C10H12F3N3O. Mole weight: 247.22. Catalog: APB09562. | |
| Sitagliptin Impurity 50 | Sitagliptin Impurity 50. Uses: For analytical and research use. Molecular formula: C15H20F3N3O3. Mole weight: 347.34. Catalog: APB09561. | |
| Sitagliptin Impurity 51 | Sitagliptin Impurity 51. Uses: For analytical and research use. CAS No. 486460-32-6. Molecular formula: C16H15F6N5O. Mole weight: 407.32. Catalog: APB486460326. | |
| Sitagliptin Impurity 52 | Sitagliptin Impurity 52. Uses: For analytical and research use. CAS No. 209995-38-0. Molecular formula: C8H5F3O2. Mole weight: 190.12. Catalog: APB209995380. | |
| Sitagliptin Impurity 58 | Sitagliptin Impurity 58. Uses: For analytical and research use. CAS No. 2033-24-1. Molecular formula: C6H8O4. Mole weight: 144.13. Catalog: APB2033241. | |
| Sitagliptin Impurity 59 | Sitagliptin Impurity 59. Uses: For analytical and research use. CAS No. 881995-70-6. Molecular formula: C11H10F3NO2. Mole weight: 245.2. Catalog: APB881995706. | |
| Sitagliptin Impurity 60 | Sitagliptin Impurity 60. Uses: For analytical and research use. CAS No. 1391554-42-9. Molecular formula: C13H14F3NO3. Mole weight: 289.25. Catalog: APB1391554429. | |
| Sitagliptin Impurity 61 | Sitagliptin Impurity 61. Uses: For analytical and research use. CAS No. 1253055-92-3. Molecular formula: C11H12F3NO2. Mole weight: 247.22. Catalog: APB1253055923. | |
| Sitagliptin Impurity 62 | Sitagliptin Impurity 62. Uses: For analytical and research use. CAS No. 1234321-83-5. Molecular formula: C13H14F3NO3. Mole weight: 289.25. Catalog: APB1234321835. | |
| Sitagliptin Impurity 63 | Sitagliptin Impurity 63. Uses: For analytical and research use. Molecular formula: C6H6F3N5O. Mole weight: 221.14. Catalog: APB09626. | |
| Sitagliptin Impurity 64 | Sitagliptin Impurity 64. Uses: For analytical and research use. CAS No. 1481965-39-2. Molecular formula: C7H7F3N4O. Mole weight: 220.16. Catalog: APB1481965392. | |
| Sitagliptin Impurity 65 | Sitagliptin Impurity 65. Uses: For analytical and research use. CAS No. 942475-04-9. Molecular formula: C11H10F2O3. Mole weight: 228.19. Catalog: APB942475049. | |
| Sitagliptin Impurity 66 | Sitagliptin Impurity 66. Uses: For analytical and research use. CAS No. 767352-24-9. Molecular formula: C11H10F2O3. Mole weight: 228.19. Catalog: APB767352249. | |
| Sitagliptin Impurity 67 | Sitagliptin Impurity 67. Uses: For analytical and research use. CAS No. 1032506-99-2. Molecular formula: C11H10F2O3. Mole weight: 228.19. Catalog: APB1032506992. | |
| Sitagliptin Impurity 68 | Sitagliptin Impurity 68. Uses: For analytical and research use. Molecular formula: C22H26Cl2F6N4O2. Mole weight: 563.37. Catalog: APB09632. | |
| Sitagliptin Impurity 69 | Sitagliptin Impurity 69. Uses: For analytical and research use. CAS No. 2248445-00-1. Molecular formula: C14H14F3NO3. Mole weight: 310.27. Catalog: APB2248445001. | |
| Sitagliptin Impurity 70 | Sitagliptin Impurity 70. Uses: For analytical and research use. CAS No. 2248445-08-9. Molecular formula: C14H17F3N2O2. Mole weight: 302.3. Catalog: APB2248445089. | |
| Sitagliptin Impurity 71 | Sitagliptin Impurity 71. Uses: For analytical and research use. CAS No. 1152439-73-0. Molecular formula: C14H11F3O5. Mole weight: 316.23. Catalog: APB1152439730. | |
| Sitagliptin Impurity 72 | Sitagliptin Impurity 72. Uses: For analytical and research use. CAS No. 762240-99-3. Molecular formula: C4H4ClF3N2O2. Mole weight: 204.53. Catalog: APB762240993. | |
| Sitagliptin Impurity 73 | Sitagliptin Impurity 73. Uses: For analytical and research use. Molecular formula: C16H13F6N5O2. Mole weight: 421.3. Catalog: APB09633. | |
| Sitagliptin Impurity 74 | Sitagliptin Impurity 74. Uses: For analytical and research use. CAS No. 1256815-03-8. Molecular formula: C10H7F3O3. Mole weight: 232.16. Catalog: APB1256815038. | |
| Sitagliptin Impurity 75 | Sitagliptin Impurity 75. Uses: For analytical and research use. Molecular formula: C21H25F6N5O4. Mole weight: 525.45. Catalog: APB09634. | |
| Sitagliptin Impurity 77 | Sitagliptin Impurity 77. Uses: For analytical and research use. Molecular formula: C16H20F3NO2. Mole weight: 315.34. Catalog: APB09568. | |
| Sitagliptin Impurity 79 | Sitagliptin Impurity 79. Uses: For analytical and research use. Alternative Names: 5-(2-(2,5-difluorophenyl)-1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione. Molecular formula: C14H12F2O5. Mole weight: 298.24. Catalog: APB01746. | |
| Sitagliptin Impurity 80 | Sitagliptin Impurity 80. Uses: For analytical and research use. Alternative Names: 5-(2-(2,4-difluorophenyl)-1-hydroxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione. Molecular formula: C14H12F2O5. Mole weight: 298.24. Catalog: APB01745. | |
| Sitagliptin Impurity 83 | Sitagliptin Impurity 83. Uses: For analytical and research use. Alternative Names: 7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine. CAS No. 2892260-32-9. Molecular formula: C6H6F3N5O. Mole weight: 221.14. Catalog: APB2892260329. | |
| Sitagliptin Intermediate 2 | Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research. Category: Active pharmaceutical ingredients. CAS No. 762240-92-6. Product ID: API762240926. Molecular formula: C6H8ClF3N4. Mole weight: 228.603. |  |
| Sitagliptin Methyl-Ester Impurity HCl | Sitagliptin Methyl-Ester Impurity HCl. Uses: For analytical and research use. CAS No. 1374985-05-3. Molecular formula: C11H13ClF3NO2. Mole weight: 283.68. Catalog: APB1374985053. | |
| Sitagliptin N-sulfate | Sitagliptin N-sulfate. Group: Biochemicals. Alternative Names: N-[ (1R) -3-[5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo[4, 3-a]pyrazin-7 (8H) -yl]-3-oxo-1-[ (2, 4, 5-trifluorophenyl) methyl]propyl]sulfamic acid. Grades: Highly Purified. CAS No. 940002-57-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H15F6N5O4S. US Biological Life Sciences. |  Worldwide |
| Sitagliptin phenylcrotonyl analog | Sitagliptin phenylcrotonyl analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Alternative Names: Sitagliptin Deamino Impurity 1; 3-Desamino-2,3-dehydro Sitagliptin; (2E)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one. Grades: >90%. CAS No. 1253056-18-6. Molecular formula: C16H12F6N4O. Mole weight: 390.28. | |
| Sitagliptin phosphate | Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor. Category: Active pharmaceutical ingredients. Synonyms: Januvia, MK-0431 phosphate, Sitagliptin (phosphate). CAS No. 654671-78-0. Product ID: API654671780. Molecular formula: C16H18F6N5O5P. Mole weight: 505.31. | |
| Sitagliptin phosphate | Sitagliptin (MK-0431) phosphate is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. Sitagliptin phosphate blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (K? = 1 nM), thereby increasing the level of active incretin. Sitagliptin phosphate can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, and this effect is independent of DPP-4. Sitagliptin phosphate shows protective effects on pancreatic islet grafts in 1-type diabetes models. Sitagliptin phosphate can be used for the study of 1-type and 2-type diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0431 phosphate. CAS No. 654671-78-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg. Product ID: HY-13749A. |  |
| Sitagliptin Phosphate | Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate. Grades: Highly Purified. CAS No. 654671-78-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin phosphate monohydrate | Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent DPP-IV inhibitor with an IC50 of 19 nM in Caco-2 cell extracts. Category: Active pharmaceutical ingredients. Synonyms: MK-0431, MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Product ID: API654671779. Molecular formula: C16H15F6N5O·H3PO4·H2O. Mole weight: 523.33. | |
| Sitagliptin phosphate monohydrate | Sitagliptin (MK-0431) phosphate monohydrate is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. Sitagliptin phosphate monohydrate blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (K? = 1 nM), thereby increasing the level of active incretin. Sitagliptin phosphate monohydrate can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, and this effect is independent of DPP-4. Sitagliptin phosphate monohydrate shows protective effects on pancreatic islet grafts in 1-type diabetes models. Sitagliptin phosphate monohydrate can be used for the study of 1-type and 2-type diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13749B. | |
| Sitagliptin Phosphate Monohydrate | Sitagliptin Phosphate Monohydrate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: MK-0431 phosphate monohydrate; 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate monohydrate. Grades: >98%. CAS No. 654671-77-9. Molecular formula: C16H20F6N5O6P. Mole weight: 523.32. | |
| Sitagliptin Phosphate Monohydrate (7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate, MK-0431) | An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates the insulin release and lowers blood glucose. Group: Biochemicals. Grades: Highly Purified. CAS No. 654671-77-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Sitagliptin Related Compound 1 | Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Alternative Names: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. Grades: >95%. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32. | |
| Sitagliptin styrylacetyl analog | Sitagliptin styrylacetyl analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Alternative Names: 3-Desamino-3,4-dehydro Sitagliptin; (3E)-1-[3-(Trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)but-3-en-1-one. Grades: >95%. CAS No. 1803026-58-5. Molecular formula: C16H12F6N4O. Mole weight: 390.28. | |
| Sitagliptin Triazecine Analog | Sitagliptin Triazecine Analog is an impurity of Sitagliptin. Sitagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor used in the treatment of diabetes mellitus type 2. Alternative Names: 10-(2,4,5-Trifluorobenzyl)-3-(trifluoromethyl)-6,7,10,11-tetrahydro-[1,2,4]triazolo[3,4-c][1,4,7]triazecine-8,12(5H,9H)-dione. Grades: > 95%. CAS No. 2805078-75-3. Molecular formula: C16H13F6N5O2. Mole weight: 421.30. | |
| Sitaxentan sodium | Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0. Alternative Names: TBC-11251; TBC 11251; TBC11251. Grades: >98%. CAS No. 210421-74-2. Molecular formula: C18H14ClN2O6S2.Na. Mole weight: 476.89. | |
| Sitaxsentan sodium | Sitaxsentan sodium (IPI 1040 sodium; TBC11251 sodium) is a potent, selective and orally active endothelin A receptor (ETA) antagonist with an IC50 of 1.4 nM and a Ki of 0.43 nM. Sitaxsentan sodium exhibits an IC50 for the ETB receptor of as high as 9800 nM. Sitaxsentan sodium is metabolized by CYP2C9 and CYP3A4, normalizes shunt-induced endothelial abnormalities, restores BMPR signaling, and suppresses pulmonary vascular remodeling and hemodynamic deterioration. Sitaxsentan sodium can be applied in the research of pulmonary arterial hypertension and portopulmonary hypertension[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPI 1040 sodium; TBC11251 sodium. CAS No. 210421-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-11103. | |
| Sitaxsentan sodium | Sitaxsentan sodium. Group: Biochemicals. Alternative Names: N-(4-Chloro-3-methyl-5-isoxazolyl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]-3-thiophenesulfonamide. Grades: Highly Purified. CAS No. 210421-74-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H14ClN2NaO6S2. US Biological Life Sciences. | Worldwide |
| site-1 protease | Cleaves sterol regulatory element-binding proteins (SREBPs) and thereby initiates a process by which the active fragments of the SREBPs translocate to the nucleus and activate genes controlling the synthesis and uptake of cholesterol and unsaturated fatty acids into the bloodstream. The enzyme also processes pro-brain-derived neurotrophic factor and undergoes autocatalytic activation in the endoplasmic reticulum through sequential cleavages. The enzyme can also process the unfolded protein response stress factor ATF6 at an Arg-His-Lys-Lys? site, and the envelope glycoprotein of the highly infectious Lassa virus and Crimean Congo hemorrhagic fever virus at Arg-Arg-Lys-Lys?. Belongs in. No. 167140-48-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4107; site-1 protease; EC 3.4.21.112; 167140-48-9; mammalian subtilisin/kexin isozyme 1; membrane-bound transcription factor site-1 protease; proprotein convertase SKI-1; proprotein convertase SKI-1/S1PPS1; S1P endopeptidase; S1P protease; site-1 peptidase; site-1 protease; SKI-1; SREBP proteinase; SREBP S1 protease; SREBP-1 proteinase; SREBP-2 proteinase; sterol regulatory element-binding protein proteinase; sterol regulatory element-binding protein site 1 protease; sterol-regulated luminal protease; subtilase SKI-1; subtilase SKI-1/S. |  |
| site-specific DNA-methyltransferase (adenine-specific) | This is a large group of enzymes, most of which form so-called 'restriction-modification systems' with nucleases that possess similar site specificity [the nucleases are listed as either EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease)]. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system. Enzyme Commission Number: EC 2.1.1.72. CAS No. 69553-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1974; site-specific DNA-methyltransferase (adenine-specific); EC 2.1.1.72; 69553-52-2; modification methylase; restriction-modification system. Cat No: EXWM-1974. | |
| site-specific DNA-methyltransferase (cytosine-N4-specific) | This is a large group of enzymes, most of which, with enzymes of similar site specificity listed as EC 3.1.21.3 (type 1 site-specific deoxyribonuclease), EC 3.1.21.4 (type II site-specific deoxyribonuclease) or EC 3.1.21.5 (type III site-specific deoxyribonuclease), form so-called 'restriction-modification systems'. A complete listing of all of these enzymes has been produced by R.J. Roberts and is available on-line at http://rebase. neb. com/rebase/rebase. html. Group: Enzymes. Synonyms: modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.113. CAS No. 169592-50-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1712; site-specific DNA-methyltransferase (cytosine-N4-specific); EC 2.1.1.113; 169592-50-1; modification methylase; restriction-modification system; DNA[cytosine-N4]methyltransferase; m4C-forming MTase; S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase. Cat No: EXWM-1712. | |
| Sitneprotafib | Sitneprotafib (JAB-3312) is an orally effective anticancer phosphatase SHP2 inhibitor (IC50: 1.9 nM) with anti-cancer activity. Sitneprotafib has good tolerability and significantly induced tumor regression in a KYSE-520 mouse xenograft model[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: JAB-3312. CAS No. 2245082-05-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161952. | |
| Sitoindoside I | Sitoindoside I. Alternative Names: 6-naphthalen-2-ylamino-1H-pyrimidine-2,4-dione. CAS No. 18749-71-8. Purity: 98%. Product ID: ACM18749718. Molecular formula: C51H90O7. Mole weight: 815.3. IUPAC Name: [(2R,3S,4S,5R,6R)-6-[[(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-3,4,5-trihydroxyoxan-2-yl]methyl hexadecanoate. Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OCC1C(C(C(C(O1)OC2CCC3(C4CCC5(C(C4CC=C3C2)CCC5C(C)CCC(CC)C(C)C)C)C)O)O)O. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Sitostanol | Stigmastanol is a 6-amino derivative. Stigmastanol can be isolated from Hypericum riparium. Stigmastanol increases the secretion of IL-2 and IL-10. Stigmastanol reduces the maximum mitochondrial respiration of cells. Stigmastanol has beneficial effects on the weakened immune function of asthma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Stigmastanol; 24α-Ethyl cholestanol. CAS No. 83-45-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113494. | |
| Sitostanol-d7 | An isotope labelled Stigmastanol (sitostanol). Stigmastanol (sitostanol) is a phytosterol found in a variety of plant sources. Similar to sterol esters and stanol esters, stigmastanol inhibits the absorption of cholesterol from the diet. Alternative Names: 5α-Cholestan-24(RS)-ethyl-3β-ol-25,26,26,26,27,27,27-d7. Grades: > 95%. Molecular formula: C29H45OD7. Mole weight: 423.77. | |
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