A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
S-Metolachlor Metabolite CGA 50720. Uses: For analytical and research use. CAS No. 152019-74-4. Mole weight: 207.23. Catalog: AP152019744.
S-(+)-Mexiletine hydrochloride
S-(+)-Mexiletine hydrochloride. Group: Biochemicals. Alternative Names: (2S)-1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride; (+)-(S)-Mexiletine hydrochloride; (+)-Mexiletine hydrochloride. Grades: Highly Purified. CAS No. 81771-85-9. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C11H18ClNO. US Biological Life Sciences.
Worldwide
SMF
SMF.
SMI-10B13
SMI-10B13 is an Oncostatin M (OSM) inhibitor with a KD of 6.6 μM. SMI-10B13 inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines (IC50 = 136 and 164 nM, respectively). SMI-10B13 shows anti-tumor effect in human breast cancer mice models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3108487-29-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175465.
SMI-4a
SMI-4a (TCS-PIM-1-4a) is a poten, selective, cell-permeable and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. SMI-4a also inhibits Pim-2 (IC50 of 100 μM), and does not significantly inhibit the other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TCS-PIM-1-4a. CAS No. 438190-29-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16576A.
SMI-4a
Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitochondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 327033-36-3. Pack Sizes: 5mg. Molecular Formula: C11H6F3NO2S, Method for Determining. US Biological Life Sciences.
Worldwide
SMIFH2
SMIFH2. Group: Biochemicals. Grades: Purified. CAS No. 340316-62-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SMIFH2
SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 340316-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16931.
SMIFH2
SMIFH2 is an inhibitor of formin homology 2 (FH2) domains. SMIFH2 prevents formin-mediated actin nucleation and barbed end elongation, disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts. Alternative Names: SMIFH-2; SMIFH 2; 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione; FH2 domain-IN-1. Grades: 98%. CAS No. 340316-62-3. Molecular formula: C15H9BrN2O3S. Mole weight: 377.21.
Smi I
One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA (SspI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme >95% of the dna fragments can be ligated and recut. ligation >95% in presence of 10% peg. Group: Restriction Enzymes. Purity: 1000U; 5000U. ATTT↑AAAT TAAA↓TTTA. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Streptococcus milleri S. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1177RE.
Smilagenin
Smilagenin (SMI) is a small-molecule steroidal sapogenin from Anemarrhena asphodeloides and Pelargonium hortorum widely used in traditional Chinese medicine for treating chronic neurodegeneration diseases[1]. Smilagenin (SMI) improves memory of aged rats by increasing the muscarinic receptor subtype 1 (M1)-receptor density[2].Smilagenin (SMI) attenuates Aβ(25-35)-induced neurodegenerationvia stimulating the gene expression of brain-derived neurotrophic factor, may represents a novel therapeutic strategy for AD[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 126-18-1. Pack Sizes: 10 mM * 1 mL in Ethanol; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106353.
SmiM I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CAYNN↑NNRTG GTRNN↓NNYAC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: Sphingobacterium mizutae M. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1178RE.
SMIP004
SMIP004 is a SKP2 E3 ligase inhibitor, which downregulates SKP2 and to stabilise p27. SMIP004 is a cancer cell selective apoptosis inducer of human prostate cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143360-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15694.
SMN-C3
SMN-C3 is an orally active SMN2 splicing modulator and has the potential to treat spinal muscular atrophy (SMA). Uses: Scientific research. Category: Signaling pathways. CAS No. 1449597-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112633.
Smoke Tree Extract (Ratio)
Smoke Tree Extract (Ratio). Group: Others. Purity: 4:1~20:1. Smoke Tree Extract (Ratio). Cat No: EXTW-051.
SMPT
SMPT is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112241-19-7. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-126405.
SMS1-IN-1
SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1807943-38-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135642.
SMS2-IN-1
SMS2-IN-1 is a potent and highly selective sphingomyelin synthase 2 (SMS2) inhibitor with an IC50 of 6.5 nM and a Kd of 37 nM. SMS2-IN-1 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098890-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102041.
SMS2-IN-2
SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively. Anti-chronic inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2241838-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112713.
SMT-738
SMT-738 is a bacterial bactericide. SMT-738 targets the small molecules responsible for lipoprotein transport in Enterobacteriaceae, causing abnormal lipoprotein localization and bacterial cell death. SMT-738 inhibits the growth of E. coli and K. pneumoniae. SMT-738 reduces bacterial loads in mouse models of urinary tract infection, bloodstream infection, and pulmonary infection caused by Enterobacterales. SMT-738 can be used in the research of Enterobacteriaceae infections, urinary tract infections, bloodstream infections, and pneumonia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2862851-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-157536.
S-MTC
S-MTC is a selective type I nitric oxide synthase (NOS) inhibitor. Uses: Enzyme inhibitors. Alternative Names: L-Ornithine, N5-[imino(methylthio)methyl]-; N5-[Imino(methylthio)methyl]-L-ornithine; (S)-2-Amino-5-((imino(methylthio)methyl)amino)pentanoic acid; S-Methyl-L-thiocitrulline; S-Methylthiocitrulline; L-S-Methylthiocitrulline; N(delta)-(S-Methylisothioureido)norvaline. Grades: ≥95%. CAS No. 156719-41-4. Molecular formula: C7H15N3O2S. Mole weight: 205.28.
SMTP-1
SMTP-1 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C25H35NO5. Mole weight: 429.5.
SMTP-2
SMTP-2 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. The activity of SMTP-2 is weaker than SMTP-1. Molecular formula: C25H37NO7. Mole weight: 463.6.
SMTP-3
SMTP-3 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C26H35NO7. Mole weight: 473.6.
SMTP-4
SMTP-4 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C32H39NO6. Mole weight: 533.7.
SMTP-5
SMTP-5 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C29H41NO6. Mole weight: 499.6.
SMTP-6
SMTP-6 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C34H40N2O6. Mole weight: 572.7.
Smurf1-IN-1
Smurf1-IN-1 is an orally active and selective inhibitor of specific E3 ubiquitin protein ligase 1 (SMURF1) with an IC50 of 92 nM. Smurf1-IN-1 has significant efficacy in rats model of pulmonary hypertension[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1824708-03-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149316.
Smurf1-IN-A01
Smurf1-IN-A01 is a Smurf1 inhibitor. Smurf1-IN-A01 has anticancer activity and can be used for the research of osteoporosis and age-related macular degeneration[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A01. CAS No. 1007647-73-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110195.
SMYD3-IN-1
SMYD3-IN-1 (compound 29) is an irreversible and selective inhibitor of SMYD3 (SET and MYND domain containing 3), with an IC50 of 11.7 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095160-79-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128352.
Smyrindioloside
Smyrindioloside. Group: Biochemicals. Grades: Plant Grade. CAS No. 87592-77-6. Pack Sizes: 5mg. Molecular Formula: C20H24O10, Molecular Weight: 424.4. US Biological Life Sciences.
Worldwide
SN-001
SN-001 is a STING inhibitor with an IC50 of 3.82 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 727699-84-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W140974.
SN 003
SN 003. Group: Biochemicals. Grades: Purified. CAS No. 197801-88-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
SN-011
SN-011 is a potent and selective STING antagonist with IC50 of 76 nM. SN-011 binds with higher affinity to the cyclic dinucleotide (CDN)-binding pocket of STING than endogenous 2'3'-cGAMP. Alternative Names: GUN35901; N-(3-(4-Fluorophenylsulfonamido)-4-hydroxyphenyl)-[1,1'-biphenyl]-4-carboxamide. CAS No. 2249435-90-1. Molecular formula: C25H19FN2O4S. Mole weight: 462.49.
SN-011
SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2249435-90-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145010.
SN05
SN05 is a potent amino acid transport (AAT) inhibitor with Ki values of 2.77 μM, 0.73 μM, 0.87 μM, 3.7 μM, 7.25 μM, 7.23 μM and 2.22 μM for hASCT1, rASCT2, hASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN05 can be used in the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2768663-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146242.
sn-1 acyl-lipid ω-3 desaturase (ferredoxin)
The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 15 of linoleoyl and γ-linolenoyl groups attached to the sn-1 position of glycerolipids. The enzyme is an ω desaturase, and determines the location of the double bond by counting three carbons from the methyl end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. cf. EC 1.14.19.35, sn-2 acyl-lipid ω-3 desaturase (ferredoxin). Group: Enzymes. Synonyms: desB (gene name). Enzyme Commission Number: EC 1.14.19.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1000; sn-1 acyl-lipid ω-3 desaturase (ferredoxin); EC 1.14.19.36; desB (gene name). Cat No: EXWM-1000.
sn-1 linoleoyl-lipid 6-desaturase
The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 6 of linoleoyl groups (18:2) attached to the sn-1 position of glycerolipids. The enzyme is a front-end desaturase, introducing the new double bond between a pre-existing double bond and the carboxyl-end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desD (gene name). Enzyme Commission Number: EC 1.14.19.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1011; sn-1 linoleoyl-lipid 6-desaturase; EC 1.14.19.46; desD (gene name). Cat No: EXWM-1011.
sn-1 oleoyl-lipid 12-desaturase
The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 12 of oleoyl groups (18:1) attached to the sn-1 position of glycerolipids. The enzyme is a methyl-end desaturase, introducing the new double bond between a pre-existing double bond and the methyl-end of the fatty acid. It is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desA (gene name). Enzyme Commission Number: EC 1.14.19.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1010; sn-1 oleoyl-lipid 12-desaturase; EC 1.14.19.45; desA (gene name). Cat No: EXWM-1010.
sn-1 stearoyl-lipid 9-desaturase
The enzyme, characterized from cyanobacteria, introduces a cis double bond at carbon 9 of stearoyl groups (18:0) attached to the sn-1 position of glycerolipids. The enzyme is nonspecific with respect to the polar head group of the glycerolipid. Group: Enzymes. Synonyms: desC (gene name). Enzyme Commission Number: EC 1.14.19.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0991; sn-1 stearoyl-lipid 9-desaturase; EC 1.14.19.28; desC (gene name). Cat No: EXWM-0991.
SN 2
SN 2. Group: Biochemicals. Grades: Purified. CAS No. 823218-99-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride is an impurity from Clopidogrel (C587250) which acts as an anti-platelet agent. Group: Biochemicals. Alternative Names: (α S) -2-Chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (S) -2-chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (α S) -2-Chloro-α - [ [2- (2-thienyl) ethyl] amino] benzeneacetic Acid Methyl Ester Hydrochloride; (+)-(S)-Methyl α-[[2-(2-Thienyl)ethyl]amino]-α-(2-chlorophenyl)acetate Hydrochloride; (S)-(+)-Methyl α-[[2-(Thien-2-yl)ethyl]amino]-α-(2-chlorophenyl)acetate Hydrochloride. Grades: Highly Purified. CAS No. 141109-19-5. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
sn-2 acyl-lipid ω-3 desaturase (ferredoxin)
This plastidial enzyme desaturates 16:2 fatty acids attached to the sn-2 position of glycerolipids to 16:3 fatty acids, and converts18:2 to 18:3 in both the sn-1 and sn-2 positions. It acts on all 16:2- or 18:2-containing chloroplast membrane lipids, including phosphatidylglycerol, monogalactosyldiacylglycerol, digalactosyldiaclyglycerol, and sulfoquinovosyldiacylglycerol. The enzyme introduces a cis double bond at a location 3 carbons away from the methyl end of the fatty acid. The distance from the carboxylic acid end of the molecule does not affect the location of the new double bond. cf. EC 1.14.19.25, acyl-lipid ω-3 desaturase (cytochrome b5) and EC 1.14.19.36, sn-1 acyl-lipid ω-3 desaturase (ferredoxin). Group: Enzymes. Synonyms: FAD7; FAD8. Enzyme Commission Number: EC 1.14.19.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0999; sn-2 acyl-lipid ω-3 desaturase (ferredoxin); EC 1.14.19.35; FAD7; FAD8. Cat No: EXWM-0999.
sn-2 palmitoyl-lipid 9-desaturase
The enzyme, characterized from the cyanobacterium Nostoc sp. 36, introduces a cis double bond at carbon 9 of palmitoyl groups (16:0) attached to the sn-2 position of glycerolipids. Group: Enzymes. Synonyms: DesC2. Enzyme Commission Number: EC 1.14.19.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0990; sn-2 palmitoyl-lipid 9-desaturase; EC 1.14.19.27; DesC2. Cat No: EXWM-0990.
SN-38
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy. Group: Inhibitors. Alternative Names: NK012. CAS No. 86639-52-3. Pack Sizes: 10mg. Product ID: S4908. Formula: C22H20N2O5. Smiles: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
SN-38
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-Ethyl-10-hydroxycamptothecin. CAS No. 86639-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13704.
SN-38. (7-Ethyl-10-hydroxycamptothecin)
A metabolite of Irinotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: 7-Ethyl-10-hydroxycamptothecin. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
SN-38 Carboxylate Disodium Salt.
The active metabolite of. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
SN-38-CO-DMEDA TFA
SN-38-CO-DMEDA TFA is the intermediate product for synthesizing antibody-conjugated drug LND1035[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1224601-17-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145767A.
SN38-COOH
SN38-COOH is used for the synthesis of antibody-drug conjugates (ADCs). SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2170118-23-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-153013.
SN-38-d3
SN-38-d3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NK012-d3. CAS No. 718612-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-13704S.
SN-38-[d3]
SN-38-[d3] is a labelled analogue of SN-38. SN-38 is the active metabolite of irinotecan. Uses: Labelled sn-38, a metabolite of irinotecan, a dna topoisomerase inhibitor. Alternative Names: SN-38 D3. Grades: 95% atom D. CAS No. 718612-49-8. Molecular formula: C22H17D3N2O5. Mole weight: 395.42.
SN-38 glucuronide
SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan (HY-16562) and has toxic effects on the gastrointestinal tract. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SN-38G. CAS No. 121080-63-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126373.
SN-38 Glucuronide
A metabolite of Irinotecan. Alternative Names: 7-Ethyl-10-hydroxy-camptothecin-10-O-b-Dglucuronide; (4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl b-D-glucopyranosiduronic acid. Grades: > 95%. CAS No. 121080-63-5. Molecular formula: C28H28N2O11. Mole weight: 568.53.
SN-38 (Standard)
SN-38 (Standard) is the analytical standard of SN-38. This product is intended for research and analytical applications. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-Ethyl-10-hydroxycamptothecin (Standard). CAS No. 86639-52-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13704R.
Induction of Glutath. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 200mg. US Biological Life Sciences.
Worldwide
SN50
SN50, a cell-permeable peptide inhibitor of NF-Κb, prevents tissue destruction (epithelial defects / ulceration) in a mouse cornea after a central alkali burn. Alternative Names: Nuclear Factor NF-KB Inhibitor SN50; NFkappaB Inhibitor. Grades: ≥97% by HPLC. CAS No. 213546-53-3. Molecular formula: C129H230N36O29S. Mole weight: 2781.5.
SN50
SN50 is a cell permeable inhibitor of NF-κB translocation. Uses: Scientific research. Category: Signaling pathways. CAS No. 213546-53-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P0151.
SN52
SN52 is a potent, competitive, and cell-permeable inhibitor of NF-κB2. SN52 is a variant of the SN50 peptide and inhibits the nuclear translocation of p52-RelB heterodimers. SN52 has a strong radiosensitization effect on prostate cancer cells. SN52 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1071173-56-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3229.
SN-6
SN-6. Group: Biochemicals. Grades: Purified. CAS No. 415697-08-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SN-706
SN-706 is an anthracycline antibiotic produced by Actinomadura reseoviolacea var miuraensis. It is active against gram-positive and gram-negative bacteria, as well as inhibits KB and HeLa cells with IC50 of 0.54 ng/mL. Alternative Names: Antibiotic SN 706; SN 706. CAS No. 114511-93-2. Molecular formula: C36H45NO14. Mole weight: 715.7.
SNA-4606-1
SNA-4606-1 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 6.6 μmol/L. Molecular formula: C52H84O18. Mole weight: 997.2.
SNA-4606-2
SNA-4606-2 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 8.7 μmol/L. Molecular formula: C53H86O18. Mole weight: 1011.24.
SNA-4606-3
SNA-4606-3 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor. Molecular formula: C55H90O17. Mole weight: 1023.3.
SNA-60-367
SNA-60-367 are a group of aromatase inhibitors produced by soil bacterium, Bacillus sp. SNA-60-367. These inhibitors are a family of acylated decapeptides that differ from each other in terms of amino acid composition and the nature of the fatty acid side chain.
SNA-8073B
SNA-8073A is an isotetracenone antibiotic isolated from the broth filtrate of Streptomyces sp. SNA-8073. It inhibited prolyl endopeptidase of Flavobacterium non-competitively with IC50 of 8.9 μmol/L. Alternative Names: SNA-8073-B. Molecular formula: C20H16O5. Mole weight: 336.3.
Snail anti-wrinkle peptide. Alternative Names: Arginine, lysine polypeptide. CAS No. 937286-43-6. Product ID: CI-BP-0013. Alfa Chemistry - ISO 9001:32057 Certified.
Snailase, Snail gastrointestinal
Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc[1]. Uses: Scientific research. Category: Enzymes. CAS No. 158736-45-9. Pack Sizes: 5 g. Product ID: HY-E70130.