A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins. Synonyms: SphK-I2; SKI-II; SKI II. Sphingosine kinase inhibitor II. Grades: >98%. CAS No. 312636-16-1. Molecular formula: C15H11ClN2OS. Mole weight: 302.78.
SKI II
SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC 50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312636-16-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13822.
Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5uM, with no inhibition against ERK2, PI3-kinase, or PKCa at concentrations up to 60uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 312636-16-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 306301-68-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
Skimmianine
Skimmianine is a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect. Skimmianine exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-95-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2081.
Skimmianine
Skimmianine. Group: Biochemicals. Alternative Names: β-Fagarine; Chloroxylonine; Pentaphylline; 7,8-Dimethoxydictamnine. Grades: Plant Grade. CAS No. 83-95-4. Pack Sizes: 20mg. Molecular Formula: C14H13NO4, Molecular Weight: 259.257. US Biological Life Sciences.
Worldwide
Skim Milk
Skim Milk - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Skim Milk Blend
Skim Milk Blend - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Skimmin
Skimmin. Group: Biochemicals. Grades: Plant Grade. CAS No. 93-39-0. Pack Sizes: 20mg. Molecular Formula: C15H16O8, Molecular Weight: 324.28. US Biological Life Sciences.
Worldwide
SkinBrite-30
SkinBrite-30 is a water soluble, diamide salt of azelaic acid that improves the technical characteristics for formulation. Azelaic acid itself has very poor water solubility, however, it is found in many grain proteins and is a beneficial component of the skin. Uses: Skin lightening, Sebum control, Moisturization. Group: Skin Care Active Ingredients. INCI Name: Potassium Azeloyl Diglycinate (PAD. CAS Number: 477773-67-4. Category: Azelaic Acid derivatives.
United States and all of its trading partners..
SkinBrite-99
SkinBrite-99 is a highly concentrated form of glycolic acid. Glycolic acid is an exfoliant. It revitalizes skin and reduces the appearance of fine lines and wrinkles by removing the outer layer of dead skin and bringing a new layer of skin to the surface. Uses: Anti-wrinkle, Exfoliation, Skin lightening, Anti-acne,. Group: Skin Care Active Ingredients. INCI Name: Glycolic Acid. CAS Number: 79-14-1.
United States and all of its trading partners..
Skirtboard Rubber
Skirtboard Rubber. Group: Polymers.
SKI V
SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC 50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC 50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24418-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12895.
SKL 2001
SKL 2001 is a Wnt/β-catenin signaling pathway agonist that modulates the differentiation of mesenchumal stem cells. It upregulates the β-catenin responsive transcription via increasing the intracellular β-catenin protein level, and inhibits the phosphorylation of β-catenin at residues Ser33/37/Thr41 and Ser45. Synonyms: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II; 5-(furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide. Grades: 99%. CAS No. 909089-13-0. Molecular formula: C14H14N4O3. Mole weight: 286.29.
SKL2001 free base
SKL-2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II. Product Category: Agonists. Appearance: Solid powder. CAS No. 909089-13-0. Molecular formula: C14H14N4O3. Mole weight: 286.29. Purity: >98%. IUPACName: 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide. Canonical SMILES: O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3. Product ID: ACM909089130. Alfa Chemistry ISO 9001:2015 Certified.
SKLB1002
SKLB1002 is a new potent VEGFR2 inhibitor, which could significantly inhibit HUVEC proliferation, migration, invasion, and tube formation. In vivo zebrafish model experiments showed that SKLB1002 remarkably blocked the formation of intersegmental vessels in zebrafish embryos. SKLB1002 inhibits angiogenesis and may be a potential drug candidate in anticancer therapy. Synonyms: SKLB1002; SKLB 1002; SKLB-1002. Grades: 0.98. CAS No. 1225451-84-2. Molecular formula: C13H12N4O2S2. Mole weight: 320.39.
SKLB-1028
SKLB1028 is a novel Bcr-abl tyrosine kinase inhibitor, Epidermal growth factor inhibitor and Fms-like tyrosine kinase 3 inhibitor originated by CSPC Ouyi Pharmaceutical. Phase-I clinical trials in Acute myeloid leukaemia (Monotherapy, Second-line therapy or greater) in China is on-going. Uses: Acute myeloid leukaemia. Synonyms: SKLB-1028; SKLB 1028; SKLB1028; 9-isopropyl-N2-(4-(4-methylpiperazin-1-yl)phenyl)-N8-(pyridin-3-yl)-9H-purine-2,8-diamine. Grades: 98%. CAS No. 1350544-93-2. Molecular formula: C24H29N9. Mole weight: 443.56.
SKLB-197
SKLB-197 is a potent and highly selective ATR inhibitor. SKLB-197 showed an IC50 value of 0.013 μM against ATR but very weak or no activity against other 402 protein kinases. It displayed potent antitumor activity against ATM-deficent tumors both in vitro and in vivo. In addition, this compound exhibited good pharmacokinetic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SKLB-197; SKLB 197; SKLB197. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2713577-16-1. Molecular formula: C25H24N6O. Mole weight: 424.51. Purity: >98%. IUPACName: Quinazoline, 2-(1H-indol-4-yl)-4-[(3R)-3-methyl-4-morpholinyl]-6-(1-methyl-1H-pyrazol-5-yl)-. Canonical SMILES: CN1N=CC=C1C2=CC3=C(N4[C@H](C)COCC4)N=C(C5=CC=CC6=C5C=CN6)N=C3C=C2. Product ID: ACM2713577161. Alfa Chemistry ISO 9001:2015 Certified.
SKLB-23bb
SKLB-23bb is an orally bioavailable and selective HDAC6 inhibitor exhibiting microtubule-disrupting ability. Synonyms: HDAC6-IN-1; N-hydroxy-4-[2-methoxy-5-[methyl-(2-methylquinazolin-4-yl)amino]phenoxy]butanamide. CAS No. 1815580-06-3. Molecular formula: C21H24N4O4. Mole weight: 396.44.
SKLB610
SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth factor receptor 2 (FGFR2) and platelet-derived growth factor receptor (PDGFR) at rate of 97%, 65% and 55%, respectively, at concentration of 10μM in biochemical kinase assays. SKLB610 exhibited its antitumor activity as a multi-targeted inhibitor with more potent inhibition of VEGFR2 activity. Its potential to be a candidate of anticancer agent is worth being further investigated. Synonyms: SKLB610; SKLB 610; SKLB-610. Grades: 0.98. CAS No. 1125780-41-7. Molecular formula: C21H16F3N3O3. Mole weight: 415.372.
SK-N-SH Transfection Reagent
Transfection Reagent for SKNSH Neuroblastoma Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 6916.
Nevada, Texas, USA
Skp2 Inhibitor C1
Skp2 Inhibitor C1(SKPin C1) is a specific small molecule inhibitor of Skp2-mediated p27 degradation, selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts. Synonyms: MDK-1699; MDK 1699; MDK1699; Skp2 inhibitor C1 and SKPin C1. Grades: >98%. CAS No. 432001-69-9. Molecular formula: C18H13BrN2O4S2. Mole weight: 465.34.
SKPin C1
SKPin C1. Group: Biochemicals. Grades: Purified. CAS No. 432001-69-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
SKQ1
SKQ1, also known as plastoquinonyl decyltriphenyl phosphonium or PDTP, is a potent mitochondria-targeted antioxidant. SKQ1 is also an API (active pharmaceutical ingredient) for making eye drop drug called Visomitin. Synonyms: SKQ1; SKQ 1; SKQ-1; PDTP; Plastoquinonyl decyltriphenyl phosphonium bromide; Visomitin. Grades: 95%. CAS No. 934826-68-3. Molecular formula: C36H42BrO2P. Mole weight: 617.61.
Skullcapflavone II
Skullcapflavone II is derived from Scutellaria baicalensis, inhibitis ovalbumin-induced airway inflammation in a mouse model of asthma. Group: Biochemicals. Grades: Highly Purified. CAS No. 55084-08-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H18O8, Molecular Weight: 374.34. US Biological Life Sciences.
Worldwide
Skullcapflavone II
Skullcapflavone II Inhibitor. Uses: Scientific use. Product Category: TN1040. CAS No. 55084-08-7.
Skullcap Herb Powder (Scutellaria Lateriflora)
Skullcap Herb Powder (Scutellaria Lateriflora).
CA, FL & NJ
Skullcap Liquid Extract(Scutellaria Lateriflora)
Skullcap Liquid Extract(Scutellaria Lateriflora).
CA, FL & NJ
Skyrin
Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 602-06-2. Pack Sizes: 1 mg. Product ID: HY-119739.
Skyrin (Rhodophyscin, Endothianin)
Non-peptidic anti-diabetic agent. Receptor-selective glucagon antagonist. Free radical species (.OH, R.) and singlet oxygen (1O2) scavenger. Mycotoxin. Cytotoxic. Antioxidant. Group: Biochemicals. Alternative Names: Rhodophyscin, Endothianin. Grades: Highly Purified. CAS No. 602-06-2. Pack Sizes: 1mg. Molecular Formula: C30H18O10. US Biological Life Sciences.
A non-peptidic anti-diabetic agent and a receptor-selective glucagon antagonist. Also acts as an antioxidant, free radical and singlet oxygen species scavenger. Group: Biochemicals. Grades: Highly Purified. CAS No. 602-06-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
SL0101
A potent and selective inhibitor of p90 Rsk, without inhibiting the function of upstream kinases such as MEK, Raf, or PKC. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
SL0101
SL0101 is a highly specific RSK inhibitor. SL0101 showed improved in vitro biological stability while maintaining specificity for RSK. These results should facilitate the development of RSK inhibitors derived from SL0101 as anticancer agents. Synonyms: SL-0101; SL 0101. CAS No. 77307-50-7. Molecular formula: C25H24O12. Mole weight: 516.455.
SL 0101-1
SL 0101-1. Group: Biochemicals. Grades: Purified. CAS No. 77307-50-7. Pack Sizes: 1mg. US Biological Life Sciences.
Inhibits the p53-MDM2 interaction (20um). Has also been shown to inhibit bovine chymotrypsin A-y. Group: Biochemicals. Alternative Names: N-Benzyloxycarbonyl-Lphenylalaninylchloro methyl ketone, ZPCK. Grades: Highly Purified. CAS No. 26049-94-5. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
SL327
SL327 is a MEK inhibitor. SL327 blocks acquisition but not expression of lithium-induced conditioned place aversion. SL327 had no affect on acquisition, expression, or extinction of EtOH-induced CPP in mice despite causing significant reduction of pERK levels in multiple brain regions. Additionally, although SL327 caused a generalized depression of locomotor activity, it did not prevent the development of EtOH-sensitization. Synonyms: SL 327; SL-327. Grades: 0.98. CAS No. 305350-87-2. Molecular formula: C16H12F3N3S. Mole weight: 335.348.
SL 327
SL 327. Group: Biochemicals. Grades: Purified. CAS No. 305350-87-2. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
SL 651498
SL 651498 is a GABAA agonist selectively for subtype α2, and has the potential for the treatment of anxiety. Uses: Potential treatment of anxiety. Synonyms: SL-65,1498; SL-651498; SL65,1498; SL651498; SL 65,1498; SL 651498; 6-fluoro-9-methyl-2-phenyl-4-(pyrrolidine-1-carbonyl)pyrido[3,4-b]indol-1-one. Grades: 99%. CAS No. 205881-86-3. Molecular formula: C23H20FN3O2. Mole weight: 389.42.
S)-(-)-Lactamide
5g Pack Size. Group: Amines, Building Blocks, Chiral Compounds, Organics, Research Organics & Inorganics. Formula: C3H7NO2. CAS No. 89673-71-2. Prepack ID 14646023-5g. Molecular Weight 89.09. See USA prepack pricing.
S-Lactoylglutathione
Cas No. 54398-03-7. Mole weight: 379.39.
Slags, lead smelting
Slags, lead smelting. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Slags, lead smelting. Product Category: Heterocyclic Organic Compound. CAS No. 69029-84-1. Product ID: ACM69029841. Alfa Chemistry ISO 9001:2015 Certified.
SLC-0111, also known as U-104, MST-104 and NSC 213841, is a potent carbonic anhydrase (CA) inhibitor (Ki values are 4.5, 45.1, 5080 and 9640 nM for CA XII, CA IX, CA I and CA II respectively in MDA-MB-231 cells). U-104 associates with CAIX/CAXII only under hypoxic conditions in vivo, reducing extracellular acidity and resulting in significant inhibition of tumor growth and metastasis in experimental models. Synonyms: 4- (3- (4-fluorophenyl) ureido) benzenesulfonamide; SLC-0111; SLC0111; SLC 0111; MST-104; MST-104; MST-104; NSC-213841; NSC213841; NSC 213841; U-104; U104; U 104. CAS No. 178606-66-1. Molecular formula: C13H12FN3O3S. Mole weight: 309.31.
SLC5111312 hydrochloride
SLC5111312 is a dual inhibitor of sphingosine kinase 1 (SPHK1) and SPHK2. Synonyms: (2S,3S)-3-hydroxy-2-[3-[6-(pentyloxy)-2-naphthalenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide monohydrochloride. Grades: ≥98%. CAS No. 1870811-01-0. Molecular formula: C22H27N5O3·HCl. Mole weight: 445.94.
SLC-(+)-Biotin
SLC-(+)-Biotin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. US Biological Life Sciences.
Worldwide
SLC-(+)-Biotin 99+% (NMR)
SLC-(+)-Biotin 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
SLC-NHS-(+)-Biotin
SLC-NHS-(+)-Biotin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
SLC-NHS-(+)-Biotin 99+%
SLC-NHS-(+)-Biotin 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg. US Biological Life Sciences.
A dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: S-1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[ (3, 3-Diphenylpropyl) methylamino]-1, 1-dimethylethyl Methyl Ester Hydrochloride. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
SLES
SLES is an anionic surfactant which is widely used in rinse off products as a primary surfactant. In addition to excellent detergency (also referred as cleansing), it also has excellent emulsification and foamability. It is major component of rinse-off products. It is compatible with all surfactants except cationic. Uses: Detergents: SLES is a key ingredient in the production of laundry detergents, dishwashing liquids, and other cleaning agents. It helps to remove dirt, grease, and stains from surfaces and fabrics.Personal care products: SLES is used as a surfactant in the production of personal care products such as shampoos, body washes, and shower gels. It helps to create a lather and cleanse the skin and hair.Oil and gas industry: SLESis used in the oil and gas industry as a drilling and fracturing fluid, as well as a gelling agent in the production of drilling muds.Industrial cleaning: SLES is used as a cleaning agent in a variety of industrial applications, including in the production of paints, inks, and other coatings.Other uses: SLES may also be used in the production of emulsifiers, wetting agents, and other chemical intermediates. Group: surfactant. Alternative Names: (Alcohols, C12-14, ethoxylated, sulfates, sodium salts;) (Linear C12-14-alkanol, ethoxylated, sulfated, sodium salt;) SLES 70%; SLES 70% 2EO; SLES 70% 3EO; Sodium Laureth Sulfate. CAS No. 9004-82-4. Pack Sizes: 200 KG / HDPE Drums Packing.
SLES 70%
SLES 70%. Market: Food Additives / Preservatives. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
SLF
SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF can be used in the synthesis of PROTAC [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195513-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114872.
SLF
SLF is a cell-permeable analog of FK-506, an immunosuppressant with high affinity for FK-506 binding protein 12 (FKBP12). SLF binds tightly to FKBP but lacks the ability to inhibit calcineurin. Synonyms: SLF Exclusive; Synthetic Ligand of FKBP. Grades: ≥98%. CAS No. 195513-96-3. Molecular formula: C30H40N2O6. Mole weight: 524.66.
SLF1081851
SLF1081851 is a Spns2 inhibitor, inhibits S1P release ( IC 50 =1.93 μM). SLF1081851 plays a key role in development and immune system [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763730-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149004.
SLF TFA
SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF TFA can be used in the synthesis of PROTAC [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2378802-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114872A.
S-Licarbazepine
(S)-10-Monohydroxy-10,11-dihydro Carbamazepine is the metabolite of Eslicarbazepine acetate, (BIA 2-093),a novel central nervous system drug. Synonyms: (10S)-10,11-Dihydro-10-hydroxy-5H-Dibenz[b,f]azepine-5-carboxamide; S-(+)-10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide; (S)-Licarbazepine; BIA 2-194; CGP 13751; Erelib; Eslicarbazepine; Pazzul; Stedesa. Grades: > 95%. CAS No. 104746-04-5. Molecular formula: C15H14N2O2. Mole weight: 254.29.