A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
KF-52 is a phosphofructokinase-1 (PFK1) inhibitor with an IC50 value of 2.1 μM. KF-52 significantly increases the ratio of oxygen consumption rate (OCR) to extracellular acidification rate (ECAR). KF-52 is applicable to research related to mitochondrial dysfunction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104612-74-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-170404.
K-FGF
It is a cell penetrating peptide. Alternative Names: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-OH; Human FGF-4; hFGF-4; Heparin-binding growth factor 4; K-fibroblast growth factor; HBGF-4; transforming protein KS3; L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-proline. Grades: >98%. Molecular formula: C74H130N16O17. Mole weight: 1515.95.
Electroporation buffer optimized for KG1 leukemia cells. Optimized electroporation protocol provided for transfection of si/miRNA, DNA, mRNA, and small proteins. Feature high transfection efficacy and cell viability. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 6576.
Nevada, Texas, USA
KG-501
KG-501 is a CREB inhibitor, with an IC50 of 6.89 μM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Naphthol AS-E phosphate. CAS No. 18228-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-103299.
KGA2727
KGA2727 is a selective and potent SGLT1 inhibitor for the treatment of diabete. Its inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and hSGLT2 respectively. It inhibited the absorption of glucose but not that of fructose. Uses: Kga2727 is used for the treatment of diabete. Alternative Names: KGA-2727; KGA 2727; 3-(3-{4-[3-(beta-D-glucopyranosyloxy)-5-isopropyl-1Hpyrazol-4-ylmethyl]-3-methylphenoxy}propylamino)propionamide. Grades: 98%. CAS No. 666842-36-0. Molecular formula: C26H40N4O8. Mole weight: 536.63.
KGA-2727
KGA-2727 is a first selective, high-affinity and orally active SGLT1 inhibitor with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 has antidiabetic efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 666842-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123797.
KGP94 is a selective inhibitor of cathepsin L with an IC50 of 189 nM[1]. KGP94 inhibits migration and invasion of metastatic carcinoma and shows low cytotoxicity (GI50=26.9 μM) against various human cell lines[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1131456-28-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118762.
KH064
KH064, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa). KH064 has anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 393569-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11059.
KH-3
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value of 0.35 μM. KH-3 has anti-proliferative activity. KH-3 suppresses breast cancer cell invasion as well as delays the initiation of lung colonies by disrupting HuR-FOXQ1 mRNA interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1215115-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134601.
KH7
KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays[1]. KH7 is also a cAMP inhibitor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 330676-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103194.
KH 7
KH 7. Group: Biochemicals. Grades: Purified. CAS No. 330676-02-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Khasianine
Khasianine. Group: Biochemicals. Alternative Names: β2-Solamargine. Grades: Plant Grade. CAS No. 32449-98-2. Pack Sizes: 10mg. Molecular Formula: C39H63NO11, Molecular Weight: 721.918. US Biological Life Sciences.
Worldwide
KH-CB19
KH-CB19 is a potent CLK (cdc2-like kinase) inhibitor (CLK1 IC50=19.7 nM; CLK3 IC50=530 nM). KH-CB19 shows antiviral activity and inhibits influenza virus replication (IC50=13.6?μM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1354037-26-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12828.
Khellin
Khellin. Group: Biochemicals. Alternative Names: 4,9-Dimethoxy-7-Methyl-5H-Furo[3,2-G]-[1]Benzopyran-5-One. Grades: Highly Purified. CAS No. 82-02-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C14H12O5. US Biological Life Sciences.
Worldwide
Khellin
5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C14H12O5. CAS No. 82-02-0. Prepack ID 13358619-5g. Molecular Weight 260.24. See USA prepack pricing.
KHKI-01215
KHKI-01215 is an inhibitor for NUAK2 with an IC50 of 0.052 μM. KHKI-01215 inhibits the proliferation of cancer cell SW480 with an IC50 of 3.16 μM, induces apoptosis in SW480. KHKI-01215 inhibits the YAP signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077585-25-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162709.
KHK-IN-1
KHK-IN-1 (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 has potential for the study of diabetes and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1303469-70-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12841.
KHK-IN-1 hydrochloride
KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1303470-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-12841A.
KHR70S hydrogenated rosin resin
KHR70S hydrogenated rosin resin.
KHS 101 hydrochloride
KHS 101 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Khusenol
Khusenol, is a component of Vetiver essential oil which is a highly esteemed basic ingredient of modern perfumery, hvaing a woody, earthy scent. Group: Biochemicals. Grades: Highly Purified. CAS No. 16223-63-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H24O, Molecular Weight: 220.35. US Biological Life Sciences.
Worldwide
Ki16425
Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK[1][2]. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Debio 0719. CAS No. 355025-24-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-13285.
Ki 16425
Ki 16425. Group: Biochemicals. Grades: Purified. CAS No. 355025-24-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ki20227
Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Alternative Names: Ki20227; Ki 20227; Ki-20227. Grades: >98%. CAS No. 623142-96-1. Molecular formula: C24H24N4O5S. Mole weight: 480.54.
Ki20227
Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 623142-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10408.
Ki 20227
Ki 20227. Group: Biochemicals. Grades: Purified. CAS No. 623142-96-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ki67 Antibody [J16J15]
Ki67,Ki-67,Ki67/MKI67,Mki67,Proliferating Cell Protein Ki-67. Group: Antibodies. Alternative Names: Proliferation marker protein Ki-67; Antigen identified by monoclonal antibody Ki-67; Antigen KI-67; Antigen Ki67; MKI67. CAS No. Pack Sizes: 20uL. Product ID: F0126. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
KI696
KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799974-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101140.
KI696 isomer
KI696 isomer is the less active isomer of KI696 (HY-101140). KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799974-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-101140A.
Ki8751
Ki8751 is a potent VEGFR2 inhibitor with an IC50 of 0.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 228559-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12038.
Ki 8751
Ki 8751. Group: Biochemicals. Grades: Purified. CAS No. 228559-41-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
KIAA0809 protein, partial (881-890)
A peptide fragment of KIAA0809 protein.
Kibdelin A
Kibdelin A is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin A is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-50-3. Molecular formula: C81H84Cl4N8O29. Mole weight: 1775.38.
Kibdelin B
Kibdelin B is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin B is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((9-methyl-1-oxodecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103528-49-0. Molecular formula: C82H86Cl4N8O29. Mole weight: 1789.41.
Kibdelin C1
Kibdelin C1 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C1 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((10-methyl-1-oxoundecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 103549-47-9. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43.
Kibdelin C2
Kibdelin C2 is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin C2 is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxododecyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-85-1. Molecular formula: C83H88Cl4N8O29. Mole weight: 1803.43.
Kibdelin D
Kibdelin D is originally isolated from Kibdelosporangium aridum subsp. largum SKF AAD-609. Kibdelin D is resistant to gram-positive bacteria and has similar effects against Staphylococcus aureus (including methicillin-resistant strains) as vancomycin. Alternative Names: Ristomycin A aglycone, 5,22,31,55-tetrachloro-7-demethyl-64-O-demethyl-56-O-(2-deoxy-2-((1-oxo-4-decenyl)amino)-beta-D-glucopyranosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 105997-86-2. Molecular formula: C81H82Cl4N8O29. Mole weight: 1773.36.
Kibdelone A
It is a potent antitumour metabolite isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. It's cytotoxic. Alternative Names: (10S,12S,13R)-4-Chloro-10,11,12,13-tetrahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-77-4. Molecular formula: C29H24ClNO10. Mole weight: 581.96.