A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Kiwi Powder | Kiwi fruit powder is made from fresh kiwi (Actinidia Chinensis), adopt the advanced spray drying technology. Kiwi juice powder is a rich source of vitamin C and vitamin A. Kiwi fruit powder can be used for drinks, health care products, baby food, puffed food, baking food, ice cream, and oatmeal. Group: Others. Kiwi Powder; Actinidia chinensis. Cat No: EXTC-083. |  |
| KJ Pyr 9 | KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay. Uses: Scientific research. Category: Signaling pathways. CAS No. 581073-80-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19735. |  |
| KKL-40 | KKL-40 is a small molecule inhibitor that targets the trans-transcription process and is effective against methicillin-sensitive and -resistant Staphylococcus aureus (S. aureus) as well as other Gram-positive pathogens including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. KKL-40 synergizes with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not synergize with other antibiotics such as daptomycin, kanamycin, or erythromycin. Trans-transcription is an extreme form of recoding, and KKL-40 inhibits trans-transcription but is nontoxic to HeLa cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865285-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116863. | |
| KL001 | KL001. Group: Biochemicals. Alternative Names: N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)-methanesulfonamide. Grades: Highly Purified. CAS No. 309928-48-1. Pack Sizes: 5mg, 10mg, 50mg. Molecular Formula: C21H22N2O4S, Molecular Weight: 398.48. US Biological Life Sciences. |  Worldwide |
| KL001 | KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 309928-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108468. | |
| KL 001 | KL 001. Group: Biochemicals. Grades: Purified. CAS No. 309928-48-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KL044 | KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801856-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119506. | |
| KL-11743 | KL-11743 is a potent, orally active and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90 and 68 nM for GLUT1, GLUT2, GLUT3 and GLUT4, respectively. It specifically blocks glucose metabolism and induces cell death in concert with electron transport inhibitors. Alternative Names: NSC783733; Acetamide, 2-[3-[6-ethoxy-4-[[4-(1H-pyrazol-4-yl)phenyl]amino]-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-. Grades: ≥98%. CAS No. 1369452-53-8. Molecular formula: C30H30N6O3. Mole weight: 522.60. |  |
| KL-11743 | KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death. In addition, KL-11743 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1369452-53-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145597. | |
| KL1333 | KL1333, a derivative of β-lapachone, is an orally available NAD+ modulator. KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear cultures[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800405-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128895. | |
| KL201 | KL201 a circadian clock modulator, is a isoform-selective cryptochrome 1 (CRY1) stabilizer. KL201 has no stabilizing effect on CRY2. KL201 lengthens the period of circadian rhythms in cells and tissues[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 302939-48-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134194. | |
| KL-50 | KL-50 is a selective toxin toward tumors that lack the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which reverses the formation of O6-alkylguanine lesions. KL-50 activates DNA damage response pathways and cycle arrest in MGMT-cells, independent of mismatch repair (MMR). KL-50 is promising for research of brain tumors that lack the DNA repair protein MGMT[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1161826-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164496. | |
| KLD12 | KLD12, a hydrogel obtained from the self-assembled peptide, regulates in vitro chondrogenesis of bovine bone marrow stromal cells. Alternative Names: Ac-Lys-Leu-Asp-Leu-Lys-Leu-Asp-Leu-Lys-Leu-Asp-Leu-NH2; N-acetyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-leucinamide; L-Leucinamide, N2-acetyl-L-lysyl-L-leucyl-L-α-aspartyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-. Grades: ≥95% by HPLC. CAS No. 800379-47-9. Molecular formula: C68H122N16O19. Mole weight: 1467.79. | |
| KLD-12 | KLD-12. CAS No. 800379-47-9. Molecular formula: C68H122N16O19. Mole weight: 1467.79. Purity: 99%. |  |
| KLD-12 TFA | KLD-12 TFA. Molecular formula: C68H122N16O19.Xc2hf3o2. Mole weight: 1467.79. Purity: 95%. | |
| Klemm's No.2 Reagent | Stain or tint etch for etching cast iron, copper and tin. | |
| Klemm's Reagent | For etching alpha-beta brass, bonze, tin, cast iron phosphides, ferrite, martensite, retained austenite, zinc and steel temper embrittlement. | |
| KLF10-IN-1 | KLF10-IN-1 (#48-15) is a KLF10 inhibitor with an IC50 value of 40 μM for KLF10 reporter gene. KLF10-IN-1 can inhibit KLF10-DNA binding and transcriptional activity, block the conversion of CD4+CD25 T cells to CD4+CD25+T regulatory cells, and inhibit the expression of KLF10 target genes. KLF10-IN-1 can be used as a useful mechanistic probe to study KLF10-mediated effects and T regulatory cell biology[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197834-98-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W181026. | |
| KLH45 | KLH45 is a potent and selective DDHD2 inhibitor, with an IC50 of 1.3 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1632236-44-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103060. | |
| KLTWQELYQLKYKGI | KLTWQELYQLKYKGI is a VEGF mimetic peptide designed based on the VEGF helix sequence 17-25, with the ability to activate VEGF receptors and exert pro-angiogenic biological activity. KLTWQELYQLKYKGI effectively promotes the attachment, spreading and proliferation of human umbilical vein endothelial cells. KLTWQELYQLKYKGI enhances the proliferation, migration and osteogenic differentiation of bone marrow stromal cells (BMSCs). KLTWQELYQLKYKGI synergistically accelerates angiogenesis and bone regeneration in rat cranial defect models. KLTWQELYQLKYKGI can be used for the research of brain tissue engineering and traumatic brain injury repair and biomaterials for bone tissue engineering and bone repair[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 917760-16-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5558. | |
| KM04416 | KM04416, an isothiazolone derivative, is a potent glycerol-3-phosphate dehydrogenase (GPD2) inhibitor. KM04416 significantly inhibits PNT1A cell proliferation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 26530-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148685. | |
| KM 11060 | KM 11060. Group: Biochemicals. Grades: Purified. CAS No. 774549-97-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| KM91104 | KM91104 is a cell-permeable V-ATPase a3-b2 inhibitor (IC50 = 2.3 μM). KM91104 reduces the metabolic activity, cell proliferation capacity and V-ATPase subunit protein expression levels of primary human hepatic stellate cells, increases intracellular ATP levels and decreases cytoplasmic pH. KM91104 reduces TLR4 expression on the surface of oligodendrocyte precursor cells, blocks the ENV-TLR4 interaction, and reverses oligodendrocyte myelination defects induced by ENV protein[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 304481-60-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135474. | |
| KME-2780 | KME-2780 is the orally active inhibitor for IRAK1 and IRAK4 with IC50s of 19 nM and 0.5 nM. KME-2780 can be used for research of dysregulation of innate immune signaling and hematologic malignancies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2968466-26-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160487. | |
| Kmeriol | Kmeriol is an extraordinary natural compound innovation, renowned for their awe-inspiring antimicrobial prowess, focusing its force on studying pathogenic bacteria. Alternative Names: 3-(3,4,5-Trimethoxyphenyl)propane-1,2-diol; 3-(3,4,5-Trimethoxyphenyl)-1,2-propanediol. Grades: 98.0%. CAS No. 54306-10-4. Molecular formula: C12H18O5. Mole weight: 242.272. | |
| KMG-104 | KMG-104 is a cell-impermeant highly selective fluorescent Mg2+ probe. KMG-104 has been used widely and revealed Mg2+ mobilization in cytoplasm in various types of cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 852057-94-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-139646. | |
| KMG-1068 | KMG-1068 (Compound 4a), a molecular glue, is a GSPT1/2 degrader. KMG-1068 effectively induces the CRBN-dependent degradation of GSPT1/2 by binding to the IMiD binding site on CRBN, facilitating the formation of a ternary complex with GSPT1/2. KMG-1068 is promising for research of cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3113750-79-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-172770. | |
| KMH-233 | KMH-233, a potent, reversible and selective inhibitor of l-type amino acid transporter LAT1/SLC7A5, inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1941174-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120139. | |
| KML-29 | KML-29 is an extremely specific monoacylglycerol lipase (MAGL) inhibitor. KML-2 should be useful to distinguish between actions of 2-arachidonoyl glycerol (an endogenous ligand of cannabinoid receptors that is deactivated by MAGL) and anandamide, another endocannabinoid. Group: Biochemicals. Alternative Names: 4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylic Acid 2,2,2-Trifluoro-1-(trifluoromethyl)ethyl Ester; 1,1,1,3,3,3-Hexafluoropropan-2-yl 4- (Bis (benzo[d][1, 3]dioxol-5-yl) (hydroxy) methyl) piperidine-1-carboxylate; KML29. Grades: Highly Purified. CAS No. 1380424-42-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| KMR-206 | KMR-206 is a PARP7 inhibitor with an IC50 of 13.7 nM. KMR-206 relieves AHR-mediated transcriptional repression and enhances CYP1A1 expression in the presence of TCDD. KMR-206 induces the STING-dependent IFN-β signaling pathway and increases the levels of STAT1, pSTAT1 and nuclear PARP7 in cancer cells. KMR-206 reduces the viability of lung adenocarcinoma cells, enhances radiation-induced immunogenic signals, and induces the production of immunogenic signals in glioblastoma cancer stem cells. KMR-206 destabilizes FRA1 to increase IRF1 levels and promotes the IRF3-CBP/p300 interaction. KMR-206 can be used in studies related to lung adenocarcinoma and glioblastoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2992741-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-17663. | |
| KMS99220 | KMS99220 is an orally active, blood-brain barrier-permeable activator of the Nrf2 inhibitory protein Keap-1. KMS99220 enhances the activity of AMPK, activates the Nrf2 signaling pathway, and reduces the phosphorylation of IκB, nuclear translocation of NFκB, as well as the phosphorylation levels of JNK, IKK and p38 MAPK via HO-1. KMS99220 binds to Keap1 to trigger the nuclear translocation of Nrf2, induces the expression of HO-1, NQO1, GCLC, GCLM and proteasome subunits; enhances proteasomal enzymatic activity; inhibits iNOS expression, nitric oxide production and IL-1β generation; attenuates microglial activation; reduces α-synuclein aggregation; and prevents dopaminergic neuron degeneration and motor dysfunction. KMS99220 prevents the degeneration of dopaminergic neurons in the substantia nigra, induces the expression of Nrf2 downstream target genes, and effectively ameliorates associated motor dysfunction in a mouse model of Parkinson's disease. KMS99220 is applicable to research related to Parkinson's disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1478585-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171705. | |
| KN-62 | KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 127191-97-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13290. | |
| KN-62 | KN-62. Group: Biochemicals. Grades: Purified. CAS No. 127191-97-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KN 92 | KN 92. Group: Biochemicals. Grades: Purified. CAS No. 1135280-28-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KN-92 | KN-92 is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 176708-42-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15517. | |
| KN-92 phosphate | KN-92 phosphate is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 phosphate is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135280-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15517A. | |
| KN 93 | KN 93. Group: Biochemicals. Grades: Purified. CAS No. 139298-40-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KN-93 | KN-93. Group: Biochemicals. Alternative Names: N- [2- [ [ [3- (4-Chlorophenyl) -2-propen-1-yl] methylamino] methyl] phenyl] -N- (2-hydroxyethyl) -4-methoxy Benzene sulfonamide. Grades: Highly Purified. CAS No. 139298-40-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C26H29ClN2O4S. US Biological Life Sciences. | Worldwide |
| KN-93 | KN-93 is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 139298-40-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15465. | |
| KN-93 hydrochloride | KN-93 hydrochloride is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1956426-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15465A. | |
| KN 93 phosphate | KN 93 phosphate. Group: Biochemicals. Grades: Purified. CAS No. 1188890-41-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| KN-93 phosphate | KN-93 phosphate is a cell-permeable, reversible and competitive inhibitor calmodulin-dependent kinase type II (CaMKII) with a Ki of 370 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1913269-12-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15465B. | |
| KN-93 (Water Soluble) | Selective Ca2+/calmodulin-dependent protein kinase II inhibitor. Insulin release inhibitor. Acid secretion inhibitor. G1 cell cycle arrest inducer. Apoptosis inducer. Ion channel inhibitor. ROS inducer. Androgen receptor inhibitor. Group: Biochemicals. Alternative Names: 2-amino-N-(4-chlorocinnamyl)-N-methylbenzylamine. Grades: Highly Purified. CAS No. 139298-40-1. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C26H29ClN2O4S H3PO4. US Biological Life Sciences. | Worldwide |
| KNK437 | KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40. Alternative Names: KNK437; KNK-437; KNK 437. Grades: 98%. CAS No. 218924-25-5. Molecular formula: C13H11NO4. Mole weight: 245.23. | |
| KNK437 | KNK437 is a HSP inhibitor, and inhibits the induction of HSP105, HSP70, and HSP40. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Heat Shock Protein Inhibitor I. CAS No. 218924-25-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-100110. | |
| Knorr-2-Chlorotrityl Resin | Knorr-2-Chlorotrityl Resin. Alternative Names: 2-Chlorotrityl chloride; (Chloro(2-chlorophenyl)methylene)dibenzene; 2-Chlorotrityl Chloride Resin; 2-Chlorophenyldiphenylmethyl Chloride; 2-Chlorotritylchloride; (2-Chlorophenyl)diphenylmethyl Chloride; 1-Chloro-2-(chlorodiphenylmethyl)benzene; Chlorotrityl chloride; 1-chloro-2-[chloro(diphenyl)methyl]benzene; 2-chlorotrityl resin; o-Chlorotriphenylchloromethane; Chloro(2-chlorophenyl)diphenylmethane; 2-Chloro-tritylchloride; 2-CHLOROPHENYLDIPHENYLCHLOROMETHANE; benzene, 1-chloro-2-(chlorodiphenylmethyl)-. Grades: 100-200 mesh,1% DVB,0.4-3.0mmol/g. CAS No. 934816-82-7. Molecular formula: C19H14Cl2. Mole weight: 312.0472558. | |
| Knorr-2-Chlorotrityl Resin | Knorr-2-Chlorotrityl Resin. Alternative Names: Knorr-2-Chlorotrityl Resin. | |
| Knorr Resin | Knorr Resin. Alternative Names: FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE LINKED TO RESIN; FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)BENZHYDRYLAMINE RESIN; RINK AMIDE,4-METHYLBENZHYDRYLAMINE POLYMER RESIN; PL-RINK MBHA RESIN. | |
| KNT-127 | KNT-127 is a selective and BBB-penetrant δ-opioid receptor (DOR) agonist (Ki = 0.16 nM). KNT-127 is highly selective to the δ receptor, with Ki values of 0.16, 21.3 and 153 nM for δ, μ and κ receptors, respectively. KNT-127 acts as a biased ligand that mainly activates cyclic adenosine monophosphate (cAMP) signaling with lower beta-arrestin signaling activation. KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens, and prefrontal cortex. KNT-127 exhibits antidepressant- and anxiolytic-like effects. KNT-127 can be studied in research on neurological diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1256921-89-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120511. | |
| Ko143 | KO143 is a potent and relatively selective ATP-binding cassette sub-family G member 2 (ABCG2 / BCRP) inhibitor. KO143 decreases the ATPase activity of ABCG2 with IC50 of 9.7 nM. Group: Inhibitors. CAS No. 461054-93-3. Pack Sizes: 5mg. Product ID: S7043. Formula: C26H35N3O5. Smiles: CC(C)CC1C2=C(CC3N1C(=O)C(NC3=O)CCC(=O)OC(C)(C)C)C4=C(N2)C=C(C=C4)OC. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| Ko 143 | Ko 143 is a potent and selective ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor. Ko 143 displays >200-fold selectivity over P-gp and MRP-1 transporters[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 461054-93-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10010. | |
| Ko 143 | Ko 143. Group: Biochemicals. Grades: Purified. CAS No. 461054-93-3. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| Kobe0065 | Kobe0065 is a novel and effective inhibitor of Ras-Raf interaction, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46±13 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 436133-68-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15716. | |
| Kobe2602 | Kobe2602 is a Ras-Raf interaction inhibitor. Kobe2602 inhibits the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki of 149 μM. Kobe2602 has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 454453-49-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-15717. | |
| Kobophenol A | Kobophenol A. CAS No. 124027-58-3. Purity: 98%. Product ID: ACM124027583. Molecular formula: C56H44O13. Mole weight: 925.0. IUPAC Name: 5-[(2S,3R,4S,5S)-4-[(2S,3S)-3-[(2R,3R)-3-(3,5-dihydroxyphenyl)-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-4-yl]-2,5-bis(4-hydroxyphenyl)oxolan-3-yl]benzene-1,3-diol. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Kobusin | Kobusin is a lignan isolated from the barks of Zanthoxylum rhetsa that exhibits antiplasmodial and anti-inflammatory properties. Alternative Names: (+)-Demethoxyaschantin; Demethoxyaschantin; Methylpiperitol; (+)-Spinescin; 5-[(3S,3aR,6S,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole. Grades: >98%. CAS No. 36150-23-9. Molecular formula: C21H22O6. Mole weight: 370.401. | |
| Kodaistatin A | Kodaistatin A is originally isolated from Asperrgilus terreus Thom DSM 11237. It inhibits the glucose-6-phosphotransferase T1 (G-6-P-T1) with the IC50 of 80 nmol/L. Molecular formula: C35H34O11. Mole weight: 630.64. | |
| Kodaistatin C | Kodaistatin B is originally isolated from Asperrgilus terreus Thom DSM 11237. It inhibits the glucose-6-phosphotransferase T1 (G-6-P-T1) with the IC50 of 130 nmol/L. Alternative Names: Kodaistatin B. Molecular formula: C35H34O12. Mole weight: 646.64. | |
| KOD DNA Polymerase from Thermococcus kodakaraensis, Recombinant | KOD is a high fidelity thermostable DNA polymerase that amplifies target DNA up to 6 kbp with superior accuracy and yield for PCR applications. The enzyme's 3'?5' exonuclease-dependent proofreading activity results in a lower PCR mutation frequency than any other commercially available DNA polymerase. The elongation rate and processivity are 5 times and 10 to 15 times higher, respectively, than for Pfu DNA polymerase, resulting in highly accurate and robust yield, in a short reaction time. Higher fidelity than pfu dna polymerase--excellent for cloninggreater yield--extension speed is 2x faster than taq dna polymerase and 5x faster than pfu dna polymerasehigher processivity--sequential nucleotide polymerization is 10- to 15-fold greater than pfu and tli dna polymerasesamplifies plasmid and lambda dna templates up to 6 kbpamplifies genomic dna templates up to 2 kbpno truncated amplification products. Group: Enzymes. Purity: > 90% homogeneous by SDS-PAGE. DNA Polymerase. Storage: at -20°C. Source: E. coli. Species: Thermococcus kodakaraensis. KOD DNA polymease; DNA polymease; KOD. Cat No: NATE-1632. | |
| Kojibiose | Kojibiose, a remarkable biomedicine, stands as a powerful solution for an array of dermatological afflictions. Renowned for its profound capacity to impede tyrosinase activity, this therapeutic wonder effectively combats skin pigmentation maladies like melasma and hyperpigmentation. Alternative Names: 2-O-(a-D-Glucopyranosyl)-a-D-glucopyranose; Glc-a-1,2-Glc; D-Glucose, 2-O-α-D-glucopyranosyl-; 2-O-α-D-Glucopyranosyl-D-glucose. Grades: ≥95%. CAS No. 2140-29-6. Molecular formula: C12H22O11. Mole weight: 342.30. | |
| Kojibiose | Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2140-29-6. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113133. | |
| kojibiose phosphorylase | The enzyme from Thermoanaerobacter brockii can act with α-1,2-oligoglucans, such as selaginose, as substrate, but more slowly. The enzyme is inactive when dissaccharides with linkages other than α-1,2 linkages, such as sophorose, trehalose, neotrehalose, nigerose, laminaribiose, maltose, cellobiose, isomaltose, gentiobiose, sucrose and lactose, are used as substrates. Group: Enzymes. Enzyme Commission Number: EC 2.4.1.230. CAS No. 206566-36-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2460; kojibiose phosphorylase; EC 2.4.1.230; 206566-36-1. Cat No: EXWM-2460. | |
| Kojic acid | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Ligands. Formula: C6H6O4. CAS No. 501-30-4. Prepack ID 31686564-100g. Molecular Weight 142.11. See USA prepack pricing. |  |
| Kojic acid | Kojic acid is a substance produced by Aspergillus oryzae that is orally effective and can also be absorbed transdermally. Kojic acid exhibits various biological activities, including anti-aging, anti-nematode, antimicrobial, antioxidant, and anti-inflammatory effects. Kojic acid is a Tyrosinase inhibitor with an Mushroom Tyrosinase IC50 of 182.7 μM. Kojic acid prevents melanin production by capturing copper ions that bind to the tyrosinase active site, thus inhibiting its activation. Kojic acid also suppresses the NF-κB and p21 signaling pathways in human keratinocytes. Kojic acid derivatives have anticancer activity[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. CAS No. 501-30-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W050154. | |
| Kojic acid | 25g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Ligands. Formula: C6H6O4. CAS No. 501-30-4. Prepack ID 31686564-25g. Molecular Weight 142.11. See USA prepack pricing. | |
| Kojic Acid | It is produced from the Aspergillus parasiticus. Kojic Acid has anti-leptospira effect with MIC of 1-10 μg/mL. It is also a tyrosinase inhibitor, which acts as a chelating agent that inhibits the production of melanin and should help chloasma in vitro. Alternative Names: 5-Hydroxy-2-(hydroxymethyl)-4-pyrone; 4H-PYRAN-4-ONE, 5-HYDROXY-2-(HYDROXYMETHYL)-; 2-Hydroxymethyl-5-hydroxy-gamma-pyrone; NSC 1942. Grades: 98%. CAS No. 501-30-4. Molecular formula: C6H6O4. Mole weight: 142.11. | |
| Kojic Acid | Kojic Acid. Synonyms: Pyran-4-one, 5-hydroxy-2-(hydroxymethyl). CAS No. 501-30-4. Pack Sizes: 5, 10, 25 g in poly bottle. Product ID: CDC10-0055. Molecular formula: C6H6O4. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Kojic Acid; CDC10-0055; 501-30-4; C6H6O4; Pyran-4-one, 5-hydroxy-2-(hydroxymethyl); 207-922-4; MFCD00006580; 501-30-4. Purity: ≥98.5% (HPLC). Color: White to beige-brown. EC Number: 207-922-4. Physical State: Crystalline Powder. Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated). Quality Level: 200. Application: kojic acid is a skin-lightening agent that acts through anti-oxidant activity. Kojic acid is a tyrosinase inhibitor, although it is not as effective as licorice extract. When combined with allantoin and other proper ingredients in sunscreen preparations, the mixture can inhibit uV-caused erythema and accelerate wound healing. It is also found to be skin sensitizing and can be irritating. Boiling Point: 179.65°C (rough estimate). Melting Point: 152-155 °C (lit.). Density: 1.1712 g/mL(rough estimate). |  |
| Kojic Acid | Kojic Acid. CAS No. 501-30-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Kojic acid 99+% | A naturally occurring chelation agent. Kojic acid may be used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors, and in cosmetics to lighten skin. As an example of the latter, it is used to treat skin diseases like melasm. Group: Biochemicals. Alternative Names: 5-Hydroxy-2-hydroxymethyl-4H-pyran-4-one; 5-Hydroxy-2-hydroxymethyl-4-pyrone; 5-Hydroxy-2-(hydroxymethyl)-4H-pyranone; 2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one; NSC 1942. Grades: Reagent Grade. CAS No. 501-30-4. Pack Sizes: 1Kg, 5Kg, 10Kg. US Biological Life Sciences. | Worldwide |
| Kojic acid dipalmitate | Kojic acid dipalmitate. Group: Biochemicals. Alternative Names: (4-Oxo-5-(palmitoyloxy)-4H-pyran-2-yl)methyl palmitate. Grades: Highly Purified. CAS No. 79725-98-7. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C38H66O6. US Biological Life Sciences. | Worldwide |
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