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| Product | Description | |
|---|---|---|
| Kibdelone B | It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Alternative Names: (10R,12R,13S)-rel-(+)-4-Chloro-6,7,10,11,12,13-hexahydro-10,12,13,15-tetrahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,5,14,16-tetrone. Grades: >95% by HPLC. CAS No. 934464-78-5. Molecular formula: C29H26ClNO10. Mole weight: 583.97. |  |
| Kibdelone C | It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin. Alternative Names: (10S,12S,13R)-4-Chloro-6,7,10,11,12,13-hexahydro-5,10,12,13,15,16-hexahydroxy-8-methoxy-2-methyl-3-propyl-2H-[1]benzopyrano[2',3':6,7]naphth[2,1-g]isoquinoline-1,14-dione; (+)-Kibdelone C. Grades: >95% by HPLC. CAS No. 934464-79-6. Molecular formula: C29H28ClNO10. Mole weight: 585.99. | |
| KI-CDK9d-32 | KI-CDK9d-32 is a highly selective and potent CDK9 PROTAC degrader (DC50: 0.89 nM). KI-CDK9d-32 promotes the ubiquitination and degradation of CDK9. KI-CDK9d-32 inhibits the MYC pathway and disrupts nucleolar homeostasis. KI-CDK9d-32 exhibits anticancer activity against acute lymphoblastic leukemia and pancreatic cancer. (Pink: CDK9 ligand (HY-153718); Blue: E3 ligase CRBN ligand (HY-163233); Black: Linker (HY-W011657); E3 ligase CRBN ligand-linker conjugate (HY-173525))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3054009-82-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-173523. |  |
| Kidney-targeted In Vivo Kit | Kidney-targeted in vivo transfection kit. Functionally tested in mice tissue-targeted delivery of siRNA and pDNA via IV,IP,IT administrations. Kit includes: In vivo delivery reagent. Transfection Enhancer reagent. Protocol for mice and rats. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 5071. |  Nevada, Texas, USA |
| Kidney-targeting peptide | Kidney-targeting peptide is a kidney-targeting peptide (KTP). Kidney-targeting peptide significantly enhances the renal targeting ability of Isoquercitrin (HY-N1445). Kidney-targeting peptide can be used in diabetic nephropathy research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3106628-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11069. | |
| KI-DX-014 | KI-DX-014 is a DDX21 inhibitor with high RNA-binding inhibitory activity (IC50 of 3.31 μM). KI-DX-014 targets DDX21s intrinsically disordered C-terminal domain, inhibits DDX21-structured RNA interaction, modulates DDX21s RNA-dependent ATPase activity, and disrupts DDX21 biomolecular condensate formation. KI-DX-014 attenuates in vitro P-TEFb release from the 7SK snRNP complex, suppresses P-TEFb-dependent RNA polymerase II CTD phosphorylation, and induces developmental defects in zebrafish embryos. KI-DX-014 acts as a chemical probe for dissecting DDX21 functions in normal physiology and disease states. KI-DX-014 can be used for cancers and neurodegenerative disorders research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1309288-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175238. | |
| kievitone hydratase | The enzyme from Fusarium sp. hydrates the methylbutenyl sidechain of the isoflavonoid phytoalexins, thus reducing their toxicity. Group: Enzymes. Synonyms: KHase; kievitone-hydrate hydro-lyase. Enzyme Commission Number: EC 4.2.1.95. CAS No. 70431-10-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5079; kievitone hydratase; EC 4.2.1.95; 70431-10-6; KHase; kievitone-hydrate hydro-lyase. Cat No: EXWM-5079. |  |
| Kif15-IN-1 | Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15), and is used for the research of cellular proliferative diseases. Uses: Scientific research. Category: Signaling pathways. CAS No. 672926-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15948. | |
| Kif15-IN-2 | Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases. Uses: Scientific research. Category: Signaling pathways. CAS No. 672926-33-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15949. | |
| KIF18A-IN-1 | KIF18A-IN-1 is an inhibitor of the mitotic kinesin KIF18A with anti-tumor activity. KIF18A targeted inhibitors may activate mitotic checkpoints and selectively kill chromosomally unstable cancer cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2600559-12-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145034. | |
| KIF18A-IN-6 | KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2914879-10-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-153065. | |
| KIF18A-IN-9 | KIF18A-IN-9 (Compound 1) is a potent KIF18A inhibitor, with an IC50 value of 3.8 nM. KIF18A-IN-9 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034541-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162531. | |
| Kifunensine | Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis. When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin. Alternative Names: [5R-(5α,6β,7α,8α,8aα)]-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione; (+)-Kifunensine; FR 900494; (5R,6R,7S,8R,8aS)-6,7,8-trihydroxy-5-(hydroxymethyl)hexahydroimidazo[1,2-a]pyridine-2,3-dione; Imidazo(1,2-a)pyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R-(5alpha,6beta,7alpha,8alpha,8aalpha))-. Grades: ≥95%. CAS No. 109944-15-2. Molecular formula: C8H12N2O6. Mole weight: 232.19. | |
| Kifunensine | Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FR-900494. CAS No. 109944-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19332. | |
| Kifunensine | Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense. It is a potent inhibitor of the mannosidase I enzyme. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Kifunensine diacetonide | Kifunensine diacetonide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Kifunensine diacetonide | Kifunensine diacetonide, an indispensable biomedicine tool revered for its potency, takes center stage in the realm of therapeutic interventions for glycoprotein-based diseases. Its remarkable prowess lies in its profound inhibition of α-mannosidase I, thereby triggering the unprecedented accumulation of high-mannose glycoproteins. This profound offering stands as a gateway to unraveling novel revelations surrounding afflictions including cancer, viral infections, and genetic disorders intimately entwined with the intricate world of protein glycosylation. Alternative Names: (3aS,3bR,7aR,11aS,11bR)-Hexahydro-2,2,5,5-tetramethyl-7H-[1,3]dioxino[4,5-e]-1,3-dioxolo[4,5-c]imidazo[1,2-a]pyridine-9,10-dione. CAS No. 134234-43-8. Molecular formula: C14H20N2O6. Mole weight: 312.32. | |
| Kigamicin A | Kigamicin A is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C34H35NO13. Mole weight: 665.64. | |
| Kigamicin B | Kigamicin B is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. Molecular formula: C40H45NO15. Mole weight: 779.78. | |
| Kigamicin C | Selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions; active in vivo against a human pancreatic cancer xenograft model; also inhibits the growth of gram positive bacteria including MRSA, but is not active against gram negative bacteria. Alternative Names: (1S,3R,4S,8aR,11aR)-3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-b-D-arabinohexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione. Grades: >98% by HPLC. CAS No. 680571-51-1. Molecular formula: C41H47NO16. Mole weight: 809.81. | |
| Kigamicin C | Kigamicin C was discovered by an anti-austerity strategy targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blocking of the activation of PKB/Akt caused by the withdrawal of nutrients. Active in vivo against a human pancreatic cancer xenograft model. Also inhibits the growth of Gram-positive bacteria including Staphylococcus aureus MRSA, but not active against Gram-negative bacteria. Group: Biochemicals. Grades: Highly Purified. CAS No. 680571-51-1. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Kigamicin D | Kigamicin D is produced by the strain of Amycolatopsis sp. ML-630-mFl. It showed activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.025-0.78 μg/mL. It also shows effect against L-1210 LB32T and other genera tumor cells with IC50 of 1 μg/mL. Alternative Names: 1,2,3a,4,6,7,10,11,12,13-Decahydro-11-[[5-[[5-[(tetrahydro-5-hydroxy-4-methoxy-6-methyl-2H-pyran-2-yl)oxy]tetrahydro-4-methoxy-6-methyl-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-10,13,15,16-tetrahydroxy-3a-methyl-7,8-(methylenedioxy)-17a-aza-3,9-dioxa-17aH-cyclopenta[b]hexaphene-14,17-dione. Molecular formula: C48H59NO19. Mole weight: 953.98. | |
| Kijanimicin | A tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin; contains an unusual nitroaminoglycoside; a potent antibacterial, antimalarial and antitumour active; inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). Alternative Names: NSC 329515; Sch 25663. Grades: >99% by HPLC. CAS No. 78798-08-0. Molecular formula: C67H100N2O24. Mole weight: 1317.51. | |
| Kijanimicin (Antibiotic Sch 25663) | Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitro-aminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor activity. However, several members of this class have received considerable literature focus. Versipelostatin was shown to inhibit transcription from the promoter of GRP78, a gene that is activated as part of a stress signaling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action was seen only in conditions of glucose deprivation and caused selective and massive killing of the glucose-deprived cells. While tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signaling pathway. Group: Biochemicals. Alternative Names: Antibiotic Sch 25663. Grades: Highly Purified. CAS No. 78798-08-0. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Kimcuongin | Kimcuongin is a coumarin isolated from Murraya paniculata leaves that has the potential to be used as a vasodilator. Alternative Names: [1-(7-methoxy-2-oxochromen-8-yl)-3-methyl-1-oxobut-2-en-2-yl] 3-methylbut-2-enoate. Grades: 98.5%. CAS No. 1872403-23-0. Molecular formula: C20H20O6. Mole weight: 356.374. | |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Alternative Names: KIN-1148; KIN 1148; KIN1148; N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide. Grades: ≥98% (HPLC). CAS No. 1428729-56-9. Molecular formula: C19H11N3OS2. Mole weight: 361.44. | |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Uses: Scientific research. Category: Signaling pathways. CAS No. 1428729-56-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101950. | |
| KIN-8194 | KIN-8194 is an orally active dual inhibitor of HCK and BTK, with IC50 values of 0.915 and <0.495 nM, respectively. KIN-8194 impairs growth and integrin-mediated adhesion of BTKi-resistant mantle cell lymphoma (MCL). KIN-8194 overcomes ibrutinib (HY-10997) resistance with a survival benefit in TMD-8 ABC DLBCL xenografted mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 330786-01-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15805. | |
| Kinamycin A | Kinamycin A is produced by the strain of Str. murayamaensis. Kinamycin A has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Alternative Names: BRN 0505520; 2,3,4-Tri(acetyloxy)-1,2,3,4,6,11-hexahydro-1,7-dihydroxy-3-methyl-6,11-dioxo-5H-benzo(b)carbazole-5-nitrile; 1,2,3-Tris(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-12-9. Molecular formula: C24H20N2O10. Mole weight: 496.42. | |
| Kinamycin B | Kinamycin B is produced by the strain of Str. murayamaensis. Kinamycin B has antibacterial and mycobacterial effects, but it has weak activity against gram-negative bacteria. Alternative Names: BRN 0503790; (1R,2R,3R,4S)-2-acetyloxy-11-diazonio-1,3,4,10-tetrahydroxy-2-methyl-9-oxo-3,4-dihydro-1H-benzo[b]fluoren-5-olate. Grades: >98%. CAS No. 35303-13-0. Molecular formula: C20H16N2O8. Mole weight: 412.35. | |
| Kinase Inhibitor Library | A unique collection of 2230 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include MAPK, PI3K, JAK, STAT, CDK, MEK, Insulin/IGF receptors, CaM Kinease II, PKA, JNK, PKC, RAF, EGFR, SAPK, GSK, MLCK, Src-family, IKK, PDGFR, VEGFR, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1600. Categories: Kinase Inhibitor Libraries. |  |
| Kinase, Natto fermentation | Kinase, Natto fermentation is a potent fibrinolytic enzyme. Kinase, Natto fermentation can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Kinase, Natto fermentation can be used for the research of cardiovascular diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 133876-92-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-P2373. | |
| Kinase(phosphorylating), acetate | Kinase(phosphorylating), acetate. Alternative Names: EC 2.7.2.1; EC: 2.7.2.1; ATP: ACETATE PHOSPHOTRANSFERASE; ACETATE KINASE; AK; Kinase (phosphorylating), acetate; ACETATE KINASE FROM ESCHERICHIA COLI; ACETATE KINASE FROM BACILLUSSTEAROTHERMO PHILUS. Grades: 95%. CAS No. 9027-42-3. | |
| Kinesin family member 27, isoform CRAb (84-103) | A peptide fragment of Kinesin family member 27, isoform CRAb. KIF27 plays an essential role in motile ciliogenesis. Alternative Names: Kinesin-Like Protein KIF27 isoform CRA_b (84-103). | |
| Kinesin-like protein KIF20A (12-20) | Kinesin-like protein KIF20A (12-20) is a 9-aa peptide. Kinesin-like protein KIF20A is a mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Alternative Names: Mitotic kinesin-like protein 2 (12-20); Rab6-interacting kinesin-like protein (12-20). | |
| Kinesin-like protein KIF20A (284-293) | Kinesin-like protein KIF20A (284-293) is a 10-aa peptide. Kinesin-like protein KIF20A is a mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Alternative Names: Mitotic kinesin-like protein 2 (284-293); Rab6-interacting kinesin-like protein (284-293). | |
| Kinesin-like protein KIF20A (809-817) | Kinesin-like protein KIF20A (809-817) is a 9-aa peptide. Kinesin-like protein KIF20A is a mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Alternative Names: Mitotic kinesin-like protein 2 (809-817); Rab6-interacting kinesin-like protein (809-817). | |
| Kinetensin | Kinetensin (human) is an endogenous neurotensin-like peptide originally isolated from pepsin-treated human plasma. It increases vascular permeability and releases histamine from rat mast cells. It induces histamine release from rat peritoneal mast cells with ED50 value of 10 mM in vitro. Alternative Names: Kinetensin (human); Neurotensin-related peptide; H-Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu-OH; L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine. Grades: ≥95%. CAS No. 103131-69-7. Molecular formula: C56H85N17O11. Mole weight: 1172.38. | |
| Kinetin | Kinetin is a type of cytokinin, a class of plant hormone that promotes cell division. Uses: Plant growth regulators. Alternative Names: 6-Furfuryladenine; Kinetin; NSC 23119; NSC-23119; NSC23119. Grades: >98%. CAS No. 525-79-1. Molecular formula: C10H9N5O. Mole weight: 215.21. | |
| Kinetin | Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 6-Furfuryladenine; N6-Furfuryladenine. CAS No. 525-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g. Product ID: HY-N0160. | |
| Kinetin | A cell division factor found in various plant parts and in yeast. A plant growth regulator. Augments growth of microbial cultures. Group: Biochemicals. Alternative Names: N-(2-Furanylmethyl)-. Grades: Highly Purified. CAS No. 525-79-1. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Kinetin Hydrochloride | Kinetin Hydrochloride. Alternative Names: KINETIN HYDROCHLORIDE;6-FURFURYLAMINOPURINE HYDROCHLORIDE;TIMTEC-BB SBB003138;KINETIN HYDROCHLORIDE 98% (HPLC);KINETIN HYDROCHLORIDE 98%;Kinetinehydrochloride;N6-Furfuryladenine,HCl;6-Furfurylaminopurine, N6-Furfuryladenine. CAS No. 177966-68-6. Purity: 96%. Product ID: ACM177966686. Molecular formula: C10H10ClN5O. Mole weight: 251.67. IUPAC Name: N-(furan-2-ylmethyl)-7H-purin-6-amine. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Kinetin Riboside | Kinetin Riboside is a cell growth inhibitor used as an anticancer and antiviral agent. Kinetin Riboside is a modified nucleoside where a furfuryl group is attached to the sixth position nitrogen of the adenosine base. This modification is utilized in biochemical research to investigate nucleic acid structure and function, RNA modification studies, and drug development due to its potential to modulate nucleic acid metabolism. Its altered chemical properties make it a valuable tool for understanding RNA biology and exploring therapeutic applications. Alternative Names: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine. Grades: 98%. CAS No. 4338-47-0. Molecular formula: C15H17N5O5. Mole weight: 347.33. | |
| Kinetin riboside-5'-diphosphate sodium salt | Kinetin riboside-5'-diphosphate sodium salt. | |
| Kinetin riboside-5'-monophosphate sodium salt | Kinetin riboside-5'-monophosphate sodium salt, a biomedical compound renowned for its efficacy in combating an array of ailments, emerges as an invaluable panacea for age-related afflictions. Devotedly addressing the challenging sphere of neurodegenerative maladies encompassing Alzheimer's and Parkinson's diseases, this therapeutic treasure trove amalgamates potent antioxidative and anti-inflammatory attributes. Consequently, it orchestrates a symphony of cellular revitalization, ushering in a respite from the ravages of time-induced degeneration. Alternative Names: 6-furfurylamino-9-b-D-ribofuranosylpurine-5'-monophosphate disodium monohydrate; [5-[6-(2-furylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid. Grades: ≥ 97% (HPLC). CAS No. 13484-67-8. Molecular formula: C15H16N5Na2O8P·H2O. Mole weight: 489.29. | |
| Kinetin Riboside-5'-monophosphorodichloridate | Kinetin Riboside-5'-monophosphorodichloridate is an intermediate used in the synthesis of Kinetin Riboside-5'-monophosphate, which can be used in pharmacological activity and therapeutic use for structure-related anticancer activity of natural cytokinins. Along with other adenosine derivatives, it can also be used in biological study for manufacture of pharmaceutical formulations for treatment against various parasites, mycoplasmas, other indications and other infections and human immunodeficiency virus inhibition. Molecular formula: C15H16Cl2N5O6P. Mole weight: 464.2. | |
| Kinetin riboside-5'-triphosphate sodium salt | Kinetin riboside-5'-triphosphate sodium salt. | |
| Kinetin Riboside (6-Furfurylaminopurine Riboside, N6-Furfuryladenosine) | Used as an anticancer and antiviral agent. Group: Biochemicals. Alternative Names: 6-Furfurylaminopurine Riboside, N6-Furfuryladenosine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Kino, eucalyptus | Kino, eucalyptus. Alternative Names: ACCROIDES GUM; GUM ACCROIDES; GUM YACCA; YACCA; RED GUM; Kino, eucalyptus; Red gum, Yacca. Grades: 95%. CAS No. 9000-20-8. Molecular formula: CAS: 9000-20-8. | |
| Kin of IRRE-like protein 3 isoform 2 precursor (402-419) | A peptide fragment of Kin of IRRE-like protein 3 isoform 2 precursor. Kin of IRRE-like protein 3 probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Alternative Names: Kin of irregular chiasm-like protein 3 isoform 2 precursor (402-419). | |
| Kinsenoside | Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD). Uses: Scientific research. Category: Signaling pathways. CAS No. 151870-74-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2292. | |
| Kinsenoside | Kinsenoside. Group: Biochemicals. Alternative Names: (+)-Kinsenoside. Grades: Plant Grade. CAS No. 151870-74-5. Pack Sizes: 25mg. Molecular Formula: C10H16O8, Molecular Weight: 264.228999999999. US Biological Life Sciences. | Worldwide |
| KIRA6 | KIRA6 is an advanced small-molecule IRE1α RNase kinase inhibitor with an IC50 of 0.6 μM[2]. KIRA6 can trigger an apoptotic response[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1589527-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19708. | |
| KIRA6 | KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Alternative Names: KIRA6; KIRA-6; KIRA 6; 1-[4-(8-amino-3-tert-butylimidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl]-3-[3-(trifluoromethyl)phenyl]urea; 1-(4-(8-amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea; KIRA analog, 2. CAS No. 1589527-65-0. Molecular formula: C28H25F3N6O. Mole weight: 518.53. | |
| Kira8 | Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG-18. CAS No. 1630086-20-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114368. | |
| Kirenol | Kirenol. Group: Biochemicals. Grades: Plant Grade. CAS No. 52659-56-0. Pack Sizes: 20mg. Molecular Formula: C20H34O4, Molecular Weight: 338.48. US Biological Life Sciences. | Worldwide |
| Kirenol | Kirenol is a diterpenoid compound, an orally active apoptosis inducer and signaling pathway regulator, with a Kd value of 5.47 μM against the target CK2. Kirenol promotes the cleavage of Bid into tBid, regulates the protein levels/phosphorylation of Bax, Bcl-2, p53 and p21, and induces caspase-independent apoptosis, S-phase cell cycle arrest, ROS accumulation and cytotoxicity in cancer cells. Kirenol activates the CK2/AKT and AMPK-mTOR-ULK1 pathways, inhibits the signaling of NF-κB, TGF-β/Smads and NLRP3 inflammasome, and regulates the GSK3β, BMP and Wnt/β-catenin pathways. Kirenol induces autophagy, mitophagy and osteoblast differentiation, promotes mitochondrial fusion, and exerts antioxidant, anti-inflammatory, antifibrotic, renoprotective, cardioprotective, neuroprotective and analgesic effects. Kirenol is applicable to research related to chronic myeloid leukemia, ischemic stroke, diabetic nephropathy, heart failure, acute lung injury and osteoporosis[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52659-56-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0559. | |
| Kirromycin | Kirromycin is an antibiotic originally isolated from Streptomyces. It was shown to inhibit protein biosynthesis via acting on elongation factor Tu (EF-Tu). Alternative Names: Mocimycin; Delvomycin. Grades: ≥95%. CAS No. 50935-71-2. Molecular formula: C43H60N2O12. Mole weight: 796.94. | |
| Kirrothricin | Kirrothricin is originally isolated from Str. cinnamomeus Tu89. It has antibacterial action, but no activity to subtilis, Escherichia coli and fungi. Alternative Names: 2H-Pyran-2-acetamide, N-((2E,4E,6S,7S,9S,10E,12E,14E,16E)-8,9-dihydroxy-6-methoxy-5,7,17-trimethyl-18-oxo-18-(1,2,5,6-tetrahydro-4-hydroxy-1-methyl-2-oxo-3-pyridinyl)-2,4-dihydroxy-5,5-dimethyl-6-((1E,3Z)-1,3-pentadienyl)-, (alphaS,2S,4S,6S)-. CAS No. 79190-00-4. Molecular formula: C44H64N2O10. Mole weight: 780.98. | |
| Kisspeptin-10, human | Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 374675-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0254. | |
| Kisspeptin-14 human | Kisspeptin-14 human is a peptide hormone encoded by the KiSS-1 gene. Kisspeptin-14 human, along with several other similar peptide hormones, is produced from a common precursor protein by cleavage by different proteases. Kisspeptin-14 human is an endogenous ligand of KISS1R. Kisspeptin-14 human has the same receptor binding efficiency and potency as full-length kisspeptin. Kisspeptin-14 human binds to its receptor GPR54 and is able to activate this G protein-coupled receptor and activate multiple intracellular signaling pathways. Kisspeptin-14 human can be used to study reproductive development and tumor metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 374675-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10489. | |
| Kisspeptin-54(human) | Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with Ki values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone[1][2][3][4][5][6][7][8]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Metastin(human). CAS No. 374683-24-6. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P1022. | |
| Kistamicin A | Kistamicin A is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 3.6 and 44. It also has anti-gram-positive bacterial effects. Alternative Names: Kistamycin A. CAS No. 155683-50-4. Molecular formula: C61H51ClN8O15. Mole weight: 1171.55. | |
| Kistamicin B | Kistamicin B is produced by the strain of Microtetraspora parvasata subsp. kistna. It has antiviral effect, and its ID50 (μg/mL) against influenza virus MDCK cells and herpes simplex virus are respectively 1.8 and 30. Alternative Names: Kistamycin B. CAS No. 155683-51-5. Molecular formula: C70H60ClN9O16. Mole weight: 1318.73. | |
| KIT-6 | KIT-6. CAS No. 12173-28-3. |  |
| Kita-kyushu lung cancer antigen 1 (76-84) | Kita-kyushu lung cancer antigen 1 (76-84) is a bioactive peptide of Kita-kyushu lung cancer antigen 1. The tumor-associated antigen Kita-Kyushu lung cancer antigen-1 has been reported as not being expressed in normal tissues, except for the testis, and in the setting of non-small cell lung cancer. Alternative Names: KK-LC-1 (76-84); Cancer / Testis Antigen 83 (76-84). | |
| Kitamycin A | It is originally isolated from Strptomyces sp. K385. Kitamycin A can inhibit the activity of plant growth. Molecular formula: C23H32N2O8. Mole weight: 464.51. | |
| Kit for Creating Hydrophilic PDMS Surface | Kit for Creating Hydrophilic PDMS Surface. | |
| KI-TOX-A3 | KI-TOX-A3 is a TOX protein-protein interaction inhibitor that blocks the TOX-KAT7 protein-protein interaction with an IC50 of 0.51 μM. KI-TOX-A3 induces proteasomal degradation of TOX, restores KAT7-mediated H3K14 acetylation, reverses exhaustion of CD8+ T cells, and inhibits the proliferation of T cell acute lymphoblastic leukemia (T-ALL) cells. KI-TOX-A3 shows promise for use in studies of hematological malignancies such as T-ALL[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1351116-34-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176244. | |
| Kiwifruit concentrate powder | Kiwifruit concentrate powder contains a naturally potent proteolytic enzyme, actinidin, which enhances protein digestion. In-vitro studies have shown that actinidin enhances the digestion of a number of different food proteins, including soy, red meat, milk, gluten and gliaden. Kiwifruit concentrate powder may also help to improve gut motility, which is an important contributor to improved bowel function. The active enzyme content of Kiwifruit concentrate powder is protected by specialised pre-processing and freeze drying techniques which maintain optimal temperature and pH conditions. Group: Others. Activity: >20,000 u/g. Appearance: green to brown powder. Form: Freeze dried powder. Source: green kiwifruit. Actinidin; Kiwifruit concentrate powder; Kiwifruit powder. Cat No: KCP-001. | |
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