A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Malonic acid disodium salt 98+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 26522-85-0. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
Malonic acid disodium salt monohydrate
100g Pack Size. Group: Building Blocks, Organics. Formula: C3H2Na2O4 ·H2O. CAS No. 26522-85-0. Prepack ID 89985621-100g. Molecular Weight 166.04. See USA prepack pricing.
Malonic Acid Disodium Salt Monohydrate
Malonic Acid Disodium Salt Monohydrate. CAS No. 26522-85-0. Molecular Formula CH2(COONa)2* H2O. Chemical Reagents
Cater Chemicals Corp. Illinois IL
Malonic acid mono-tert-butyl ester
Malonic acid mono-tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 40052-13-9. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C7H12O4. US Biological Life Sciences.
Worldwide
Malonoben
Malonoben. Group: Biochemicals. Grades: Purified. CAS No. 10537-47-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Malononitrile,
Malononitrile. Tyger suppliers of organic specialty chemicals & custom chemical synthesis.
Involved in an early step of biotin biosynthesis in Gram-negative bacteria. This enzyme catalyses the transfer of a methyl group to the ω-carboxyl group of malonyl-[acyl-carrier protein] forming a methyl ester. The methyl ester is recognized by the fatty acid synthetic enzymes, which process it via the fatty acid elongation cycle to give pimelyl-[acyl-carrier-protein] methyl ester. While the enzyme can also accept malonyl-CoA, it has a much higher activity with malonyl-[acyl-carrier protein]. Group: Enzymes. Synonyms: BioC. Enzyme Commission Number: EC 2.1.1.197. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1796; malonyl-[acyl-carrier protein] O-methyltransferase; EC 2.1.1.197; BioC. Cat No: EXWM-1796.
malonyl-CoA decarboxylase
Specific for malonyl-CoA. The enzyme from Pseudomonas ovalis also catalyses the reaction of EC 2.8.3.3 malonate CoA-transferase. Group: Enzymes. Synonyms: malonyl coenzyme A decarboxylase; malonyl-CoA carboxy-lyase. Enzyme Commission Number: EC 4.1.1.9. CAS No. 9024-99-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4839; malonyl-CoA decarboxylase; EC 4.1.1.9; 9024-99-1; malonyl coenzyme A decarboxylase; malonyl-CoA carboxy-lyase. Cat No: EXWM-4839.
Malonyl CoA lithium
Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Malonyl coenzyme A lithium. CAS No. 108347-84-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136408.
Requires Mg2+. Catalyses the reduction of malonyl-CoA to malonate semialdehyde, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutanoate cycles, autotrophic CO2 fixation pathways found in some green non-sulfur phototrophic bacteria and some thermoacidophilic archaea, respectively. The enzyme from Sulfolobus tokodaii has been purified, and found to contain one RNA molecule per two subunits. The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyses the next reaction in the pathway, EC 1.1.1.298 [3-hydroxypropionate dehydrogenase (NADP+)]. Group: Enzymes. Synonyms: NADP-dependent malonyl CoA reductase; malonyl CoA reductase (NADP); malonyl CoA reductase (malonate semialdehyde-forming). Enzyme Commission Number: EC 1.2.1.75. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1177; malonyl-CoA reductase (malonate semialdehyde-forming); EC 1.2.1.75; NADP-dependent malonyl CoA reductase; malonyl CoA reductase (NADP); malonyl CoA reductase (malonate semialdehyde-forming). Cat No: EXWM-1177.
Malonyl coenzyme A lithium salt
Malonyl coenzyme A lithium salt is a coenzyme A derivative of malonic acid. Malonyl CoA is involved in chain elongation during fatty acid and polyketide synthesis. Malonyl CoA is also used in transporting alpha-ketoglutarate across the mitochondrial membrane into the mitochondrial matrix. Applications: A coenzyme a derivative involved in fatty acid regulation and biosynthesis. Group: Coenzymes. CAS No. 108347-84-8. Purity: ≥90%. Mole weight: 853.58. Appearance: Powder. Form: Solid. Malonyl coenzyme A lithium salt; 108347-84-8. Cat No: COEC-009.
Malonyl coenzyme A lithium salt
Malonyl coenzyme A lithium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 108347-84-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C24H38N7O19P3S·xLi. US Biological Life Sciences.
Worldwide
Malonyl coenzyme A tetralithium salt
Malonyl coenzyme A tetralithium salt. Uses: For analytical and research use. CAS No. 116928-84-8. Mole weight: 877.31. Catalog: AP116928848.
Malonyl-L-carnitine-d3 Trifluoroacetate
Malonyl-L-carnitine-d3 Trifluoroacetate is the labeled analogue of Malonyl-L-carnitine Chloride, a biomarker for apoptosis in cancer cell lines. Group: Biochemicals. Alternative Names: (2R)-3-Carboxy-2-[(carboxyacetyl)oxy]-N,N,N-trimethyl-d3-1-propanaminium Trifluoroacetate, (R)-3-Carboxy-2-(2-carboxyacetoxy)-N,N,N-trimethyl-d3-propan-1-aminium Trifluoroacetate. Grades: Highly Purified. CAS No. 910825-21-7. Pack Sizes: 2.5mg. Molecular Formula: C12H15D3F3NO8. US Biological Life Sciences.
Worldwide
malonyl-NAC
malonyl-NAC increases cellular propylation, resulting in reduced endogenous GAPDH activity. malonyl-NAC increases GAPDH malonylation in cells and inhibits pyruvate kinase activity. In addition, malonyl-NAC limits the metabolism and proliferation of a highly glycolytic kidney cancer cell line harboring a tricarboxylic acid cycle mutation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361327-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157395.
malonyl-S-ACP:biotin-protein carboxyltransferase
Derived from the components MadC and MadD of the anaerobic bacterium Malonomonas rubra, this enzyme is a component of EC 4.1.1.89, biotin-dependent malonate decarboxylase. The carboxy group is transferred from malonate to the prosthetic group of the biotin protein (MadF) with retention of configuration. Similar to EC 4.1.1.87, malonyl-S-ACP decarboxylase, which forms part of the biotin-independent malonate decarboxylase (EC 4.1.1.88), this enzyme also follows on from EC 2.3.1.187, acetyl-S-ACP:malonate ACP transferase, and results in the regeneration of the acetyl-[acyl-carrier protein]. Group: Enzymes. Synonyms: malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase; MadC/MadD; MadC,D; malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase. Enzyme Commission Number: EC 2.1.3.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2012; malonyl-S-ACP:biotin-protein carboxyltransferase; EC 2.1.3.10; malonyl-S-acyl-carrier protein:biotin-protein carboxyltransferase; MadC/MadD; MadC,D; malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxyltransferase. Cat No: EXWM-2012.
malonyl-S-ACP decarboxylase
This enzyme comprises the β and γ subunits of EC 4.1.1.88 (biotin-independent malonate decarboxylase) but is not present in EC 4.1.1.89 (biotin-dependent malonate decarboxylase). It follows on from EC 2.3.1.187, acetyl-S-ACP:malonate ACP transferase, and results in the regeneration of the acetylated form of the acyl-carrier-protein subunit of malonate decarboxylase. The carboxy group is lost with retention of configuration. Group: Enzymes. Synonyms: malonyl-S-acyl-carrier protein decarboxylase; MdcD/MdcE; MdcD,E. Enzyme Commission Number: EC 4.1.1.87. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4836; malonyl-S-ACP decarboxylase; EC 4.1.1.87; malonyl-S-acyl-carrier protein decarboxylase; MdcD/MdcE; MdcD,E. Cat No: EXWM-4836.
Malotilate
Malotilate. Group: Biochemicals. Grades: Highly Purified. CAS No. 59937-28-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Mal-PEG12-NHS ester
Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2669737-09-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-140963.
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.
MAL-PEG2000-NH2TFA
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Mole weight: average Mn 2000. Purity: ≥95%.
Mal-PEG24-NHS ester
Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226733-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135819.
Mal-PEG2-acid
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374666-32-6. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-130442.
Mal-PEG2-acid
Mal-PEG2-acid. Alternative Names: Mal-PEG2-CH2CH2COOH. CAS No. 1374666-32-6. Purity: >90%. Product ID: ACM1374666326. Molecular formula: C11H15NO6. Mole weight: 257.24. IUPAC Name: 3-[2-[2-(2,5-Dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid. Alfa Chemistry - ISO 9001:32057 Certified.
Mal-PEG2-alcohol
Mal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34321-81-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-140968.
Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 (Compound DC-2) is a drug-linker conjugate for ADC. Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 consists of a NMT inhibitor (HY-160945) and a stable and cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)). Mal-PEG2-amide-C2-amide-Phenyl(β-D-glucuronide)-NMT-IN-7 can be used for synthesis of ADCs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032302-82-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-171814.
Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan
Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a bioactive drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC). Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is applicable to ADC synthesis and cancer research. Exatecan acts as a DNA Topoisomerase I inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599439-54-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-153795.
Mal-PEG2-NHS
Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329364-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138430.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate. CAS No. 1433997-01-3. Purity: >90%. Product ID: ACM1433997013. Molecular formula: C15H18N2O8. Mole weight: 354.31. IUPAC Name: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate. Alfa Chemistry - ISO 9001:32057 Certified.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a non-cleavable ADC linker containing the Maleimide group, 2-unit PEG, and NHS ester. Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]-1H-pyrrole-2,5-dione; 2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoate. Grade: ≥98%. CAS No. 1433997-01-3. Molecular formula: C15H18N2O8. Mole weight: 354.31.
Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester. Uses: Scientific research. Category: Signaling pathways. CAS No. 1433997-01-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126504.
Mal-PEG2-VCP-Eribulin
Mal-PEG2-VCP-Eribulin consists the ADCs linker (Mal-PEG2-VCP) and Eribulin (HY-13442). Eribulin is a mechanistically unique microtubule inhibitor and Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules. Mal-PEG2-VCP-Eribulin is an Eribulin-based agent for antibody conjugates[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2130869-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128870.
Mal-PEG3-NH2 TFA
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 TFA is a crosslinking reagent with a PEG spacer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2830214-77-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W190796A.
Mal-?PEG4-?NHS ester
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1325208-25-0. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126505.
Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2112738-09-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140145.
Mal-PEG4-VA-PBD
Mal-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA. Uses: Scientific research. Category: Signaling pathways. CAS No. 1342820-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126685.
Mal-PEG4-VC-PAB-DMEA-PNU-159682
Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2259318-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-126687.
Mal-PEG5000-OH
Mal-PEG5000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolides poor water solubility and reduce its toxicity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Maleimide-PEG5000-Hydroxy. CAS No. 88504-24-9. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-155902.
Mal-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 518044-42-3. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-126963.
Mal-PEG6-CH2CH2COOH
Mal-PEG6-CH2CH2COOH. CAS No. 518044-42-3. Purity: Min. 95%. Product ID: ALC-FP-518044423. Molecular formula: C19H31NO10. Mole weight: 433.45 g/mol. Alfa Chemistry - ISO 9001:32057 Certified.
Mal-PEG6-mal
Mal-PEG6-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2752168-26-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133353.
Mal-PEG6-NHS ester
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599472-25-9. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-130085.
Mal-PEG6-NHS ester
Mal-PEG6-NHS ester. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 1-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-3,6,9,12,15,18-hexaoxahenicosan-21-oate. CAS No. 1599472-25-9. Purity: >90%. Product ID: ACM1599472259. Molecular formula: C23H34N2O12. Mole weight: 530.5. IUPAC Name: (2,5-Dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate. Alfa Chemistry - ISO 9001:32057 Certified.
Mal-PEG8-NHS ester
Mal-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Category: Signaling pathways. CAS No. 2055033-05-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-126887.
Mal-PEG8-Val-Ala-PAB-Exatecan
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2679821-39-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147271.
Mal-PEG8-Val-Cit-PAB-MMAE
Mal-PEG8-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3058970-85-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-141156.
MALT1 Inhibitor I, MI-2 (ALB-H03200218, 2-Chloro-N-(4-(5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl)phenyl)acetamide)
A cell-permeable chloromethyl amide that inhibits MALT1 proteolytic activity (IC50 = 5.84uM against MALT1 paracaspase domain dimer-catalyzed Ac-LRSR-AMC hydrolysis) in an irreversible manner via covalent interaction, displaying little or no activity against caspase-3, -8, or -9. Due to irreversible binding and effective intracellular accumulation (HBL-1 intracellular [MI-2]t = 2h = 5uM; Medium [MI-2]t = 0 = 0.2uM), MI-2 is at least 250-times more effective than Z-VRPR-FMK in blocking constitutive NF-kappaB activity and c-Rel nuclear translocation in HBL-1 cultures (equal or better blockage by 200nM MI-2 than by 50uM Z-VRPR-FMK). Shown to selectively inhibit MALT1-dependent ABC-DLBCL proliferation, but not the MALT1-independent growths of ABC- (HLY-1 and U2932) or GCB-DLBCL (OCI-Ly1 and OCI-Ly7) cells, both in cultures in vitro (GI50 in 48h = 200, 400, 400, and 500nM, respectively, against HBL-1, OCI-Ly3, OCI-Ly10, and TMD8) and in mice in vivo (65%,, 61%, and 0% suppression, respective Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
MALT1 inhibitor MI-2
MALT1 inhibitor MI-2 is a MALT1 inhibitor (IC50=5.84 μM). MALT1 inhibitor MI-2 binds directly to MALT1, irreversibly suppresses protease function and is accompanied by NF-κB reporter activity suppression, c-REL nuclear localization inhibition, and NF-κB target gene downregulation. MALT1 inhibitor MI-2 shows nontoxic to animals[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1047953-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12276.
Maltitol
Maltitol. CAS No. 585-88-6. Product ID: PE-0485. Molecular formula: C12H24O11. Mole weight: 344.32. Category: Coating material; Diluent; Granulating Agents; Suspension aid; Sweetener; Viscosifier. Product Keywords: Sweeteners Excipients; Suspending Agents; PE-0485; Maltitol; Coating material; Diluent; Granulating Agents; Suspension aid; Sweetener; Viscosifier; C12H24O11; 585-88-6. UNII: NA. Chemical Name: 4-O-α-D-Glucopyranosyl-D-glucitol. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Oral preparations. Stability and Storage Conditions: Maltitol has good temperature and chemical stability. Degradation occurs when heated above 200°C (depending on time, temperature, and other major conditions). Maltitol reacts with amino acids to turn brown. Only when the relative humidity is 89% or higher at 20°C. Source and Preparation: Maltitol is prepared from hydrogenated malt syrup. The starch is hydrolyzed to produce a high concentration of maltose, which is then hydrogenated with a catalyst. After purification and concentration, the syrup is crystallized. Applications: Maltitol is widely used in oral preparations in the pharmaceutical industry. It is non-carious substance. Similar in sweetness to sucrose, it can be used as a diluent in oral dosage form and also in wet granulating and coating materials.
Maltitol
Maltitol is a sugar alcohol, used as a sugar replacer. Group: Biochemicals. Grades: Highly Purified. CAS No. 585-88-6. Pack Sizes: 5g, 25g. Molecular Formula: C12H24O11, Molecular Weight: 344.31. US Biological Life Sciences.
Worldwide
Maltitol Solution
Maltitol Solution. CAS No. 9053-46-7. Product ID: PE-0490. Category: Suspension aid; Sweetener. Product Keywords: Sweeteners Excipients; Suspending Agents; PE-0490; Maltitol Solution; Suspension aid; Sweetener; ; 9053-46-7. UNII: NA. Chemical Name: Maltitol solution. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Candies. Stability and Storage Conditions: Spitol solution can be stable for at least two years at room temperature and pH3~9. However, when stored at 50°C, pH2 for 3 months, there is 1.2% hydrolysis, and the color turns yellow. At pH3, the discoloration was not significant despite hydrolysis (0.2%) under the same storage conditions. At pH4~9, although under alkaline conditions, there is a slight yellowing, but not hydrolysis. Maltitol solutions should be supplemented with antibacterial preservatives, such as sodium benzoate or a mixture with hydroxybenzene. Maltitol solution is non-crystalline. Maltitol solution should be stored in an airtight container and kept in a cool, dry place. Source and Preparation: Maltitol is produced by hydrogenation of high concentration maltitol liquid resulting from amylysis. The resulting maltitol solution contains hydrogenated homologues of oligosaccharides in the raw sugar solution. Applications: Maltitol solution can be used alone or in combination with other excipients such as sorbitol as a sweetener in the prescription of oral pharmaceutical
Maltobionic acid
Maltobionic acid. CAS No. 534-42-9. Pack Sizes: 1 kg/bag,25 kg/bag or as your requirements. Product ID: CDC10-0236. Molecular formula: C12H22O12. Category: Buffering Agents. Product Keywords: Cosmetic Ingredients; Buffering Agents; Maltobionic acid; CDC10-0236; 534-42-9; C12H22O12; 534-42-9. Purity: 99%min. Color: White Crystalline. EC Number: N/A. Physical State: Powder. Boiling Point: 864.7±65.0 °C(Predicted). Melting Point: 155-157 °C (decomp). Density: 1.79±0.1 g/cm3(Predicted). Product Description: Maltobionic acid, a fourth-generation fruit acid, is a new type of multi-hydroxyl group derived from the fermentation and oxidation of natural maltose. Structured lactobionic acid is gentle on the skin, skin-friendly, and helps in skin care. Maltobionic acid is used to strengthen translucent skin, increase skin elasticity, effectively improve fine lines and roughness of the skin. The molecular structure of maltobionic acid has a lactose structure, which increases glycosaminoglycans, strengthens the skins moisture, and makes the skin plump and smoother.
Maltobionic acid
Maltobionic acid (4-O-α-D-Glucopyranosyl-D-gluconic acid) is an orally active oligosaccharide and iron chelator with antibacterial activity. Maltobionic acid inhibits the expression of NFATc1, suppresses osteoclast differentiation, inhibits bone resorption, and increases serum calcitonin levels. Maltobionic acid protects mammalian cells from hydrogen peroxide (H2O2)-induced oxidative damage; resists fermentation by the gut microbiota; and exhibits anti-digestive and anti-fermentative properties. Maltobionic acid can be used in research related to osteoporosis, bacterial infections, and constipation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4-O-α-D-Glucopyranosyl-D-gluconic acid. CAS No. 534-42-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W423191.
Maltodextrin
Maltodextrin. CAS: 9050-36-6. Packing: Bag.
New Jersey NJ
Maltodextrin
Maltodextrin FCC is a non-sweet, nutritive saccharide that is produced as a odorless, white powder. Some of the properties which make maltodextrins highly versatile are low sweetness, binding properties, solubility, nonhygroscopic, crystal growth inhibition, low browning tendency, viscosity/body agent, freezing point control, low osmotic pressure, and film forming properties. Uses: Artificial Sweetener, Flavor Enhancer, Meat Products, Sauces. Alternative Names: E 1400, Clintose CR 10, Maltrin M100, Globe Plus 10 DE. Grades: FCC. CAS: 9050-36-6. Pack Sizes: 50 Lb.
USA
Maltodextrin
Maltodextrin is a polysaccharide that is used primarily in foods and beverages as a thickener, sweetener, and/or stabilizer. It is produced from vegetable starch by partial hydrolysis and is usually found as a white hygroscopic spray-dried powder. Maltodextrin is easily digestible, being absorbed as rapidly as glucose and may be either moderately sweet or almost flavorless. It can be found as an ingredient in a variety of processed foods. Uses: Chocolates & confectionery Baby food & pharmaceuticals Energy drinks & bars Milk & bakery products. Group: Natural Product. Alternative Names: Corn Syrup Solids Modified Corn Starch Modified Rice Starch Modified Tapioca Starch Modified Wheat Starch. Grades: Industrial Grade, Food Grade, Pharmaceutical Grade. CAS No. 9050-36-6. Pack Sizes: 25kg Paper / HDPE bags.
Maltodextrin
Maltodextrin. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
California
Maltodextrin
Maltodextrin is a carbohydrate derived from starch. Alternative Names: Dextrin maize starch. CAS No. 9050-36-6. Molecular formula: C12H22O11. Mole weight: 342.3. Purity: 98%.
Maltodextrin
Maltodextrin occurs as a nonsweet, odorless, white powder or granules. The solubility, hygroscopicity, sweetness, and compressibility of maltodextrin increase as the DE increases. Synonyms: Cargill Dry. CAS No. 9050-36-6. Product ID: PE-0189. Molecular formula: (C6H10O5)n·H2O. Mole weight: 900-9000. Category: Coating Agents; Tablet and Capsule Diluent; Tablet Binder; Viscosity increasing Agents; Filler; Stabilizer; Thickening Agents; Surface polish, etc. Product Keywords: Thickener Excipients; Stabilizers; Thickener Excipients; ; PE-0189; Maltodextrin; Coating Agents; Tablet and Capsule Diluent; Tablet Binder; Viscosity increasing Agents; Filler; Stabilizer; Thickening Agents; Surface polish, etc; (C6H10O5)n·H2O; 9050-36-6. UNII: 7CVR7L4A2D. Chemical Name: Maltodextrin. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Oral tablets and granules. Stability and Storage Conditions: Maltodextrin is stable for at least 1 year when stored at a cool temperature (<30°C) and less than 50% relative humidity.Maltodextrin solutions may require the addition of an antimicrobial preservative. Maltodextrin should be stored in a well-closed container in a cool, dry place. Source and Preparation: Maltodextrin is prepared by heating and treating starch with acid and/or enzymes in the presence of water. This process partially hydrolyzes the starch, to produce a solution of glucose polymers of varying chain length.
Maltodextrin BP/USP
Maltodextrin BP/USP. CAS No. 9050-36-6.
Maltodextrin, dextrose equivalent 5.0-8.0
Maltodextrin, dextrose equivalent 5.0-8.0 can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9050-36-6. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W250795B.
Maltogenic α-amylase 13A from Lactobacillus gasseri, Recombinant
Glucan 1,4-alpha-maltohydrolase (EC 3.2.1.133, maltogenic alpha-amylase, 1,4-alpha-D-glucan alpha-maltohydrolase) is an enzyme with system name 4-alpha-D-glucan alpha-maltohydrolase. This enzyme catalyses the following chemical reaction:hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains. This enzyme acts on starch and related polysaccharides and oligosaccharides. Group: Enzymes. Synonyms: Glucan 1,4-alpha-maltohydrolase; EC 3.2.1.133; maltogenic alpha-amylase; 1,4-alpha-D-glucan alpha-maltohydrolase; Glucan 1,4-α-maltohydrolase, Maltogenic Amylase, Novamyl 1000BG. Enzyme Commission Number: EC 3.2.1.133. CAS No. 160611-47-2. Purity: >90% by SDS-PAGE. α-Amylase. Mole weight: 55.0 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Lactobacillus gasseri. Glucan 1,4-alpha-maltohydrolase; EC 3.2.1.133; maltogenic alpha-amylase; 1,4-alpha-D-glucan alpha-maltohydrolase; Glucan 1,4-α-maltohydrolase, Maltogenic Amylase, Novamyl 1000BG. Cat No: NATE-1298.
Maltogenic α-amylase 13A from Thermotoga neapolitana, Recombinant
Glucan 1,4-alpha-maltohydrolase (EC 3.2.1.133, maltogenic alpha-amylase, 1,4-alpha-D-glucan alpha-maltohydrolase) is an enzyme with system name 4-alpha-D-glucan alpha-maltohydrolase. This enzyme catalyses the following chemical reaction:hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains. This enzyme acts on starch and related polysaccharides and oligosaccharides. Group: Enzymes. Synonyms: Glucan 1,4-alpha-maltohydrolase; EC 3.2.1.133; maltogenic alpha-amylase; 1,4-alpha-D-glucan alpha-maltohydrolase; Glucan 1,4-α-maltohydrolase, Maltogenic Amylase, Novamyl 1000BG. Enzyme Commission Number: EC 3.2.1.133. CAS No. 160611-47-2. Purity: >90% by SDS-PAGE. α-Amylase. Mole weight: 52.1 kD. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Thermotoga neapolitana. Glucan 1,4-alpha-maltohydrolase; EC 3.2.1.133; maltogenic alpha-amylase; 1,4-alpha-D-glucan alpha-maltohydrolase; Glucan 1,4-α-maltohydrolase, Maltogenic Amylase, Novamyl 1000BG. Cat No: NATE-1297.
Maltogenic amylase
A unique maltogenic amylase enzyme used to produce large quantities of fermentable maltose sugar. Applications: Saccharification. Group: Enzymes. Synonyms: maltogenic amylase; maltogenic amylase enzyme; Saccharification enzyme; maltose sugar as Free-Amino-Nitrogen; Saccharification; Brewing; as FAN; FAN; BRE-1616. maltogenic amylase. Appearance: powder or liquid. maltogenic amylase; maltogenic amylase enzyme; Saccharification enzyme; maltose sugar as Free-Amino-Nitrogen; Saccharification; Brewing; as FAN; FAN; BRE-1616. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form) or subject to client requirement. Cat No: BRE-1616.
Maltogenic amylase for baking
A maltogenic amylase, which effectively hydrolyzes starch in flour, producing maltose and low molecular weight sugars. Applications: Extend shelf life. Group: Enzymes. Synonyms: Maltogenic amylase for baking; maltogenic amylase; Extend Shelf Life enzyme; BAK-1712. maltogenic amylase. Appearance: powder or liquid. maltogenic amylase; maltogenic amylase enzyme; Saccharification enzyme; maltose sugar as Free-Amino-Nitrogen; Saccharification; Brewing; as FAN; FAN; BRE-1616. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BAK-1712.