A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
VCPIP1-IN-1 (Compound 076) is a VCPIP1 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3025298-68-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-159000.
VCP/p97 inhibitor-1
VCP/p97 inhibitor-1 is a potent inhibitor of VCP/p97 (also called Cdc48, CDC-. 48, or Ter94) with an IC50 of 54.7 nM. VCP/p97 inhibitor-1 causes the dysregulation of protein homeostasis and disturbs the degradation of misfolded polypeptides by the ubiquitin-proteasome system (UPS)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2630950-38-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-139606.
VC Propylene glycol hyaluronate
VC Propylene glycol hyaluronate can effectively inhibit the synthesis of melanin, reduce the appearance of skin pigmentation, and play a role in whitening, anti-oxidation and anti-wrinkle. In addition, it can improve the moisturizing effect of the skin, inhibit the synthesis of melanin, and promote the synthesis of collagen, which are key factors in skin whitening and anti-aging. Grade: ≥95%.
VCr4Ti4 Alloy Powder
VCr4Ti4 alloy powder is usually composed of tungsten, chromium, titanium and other elements, with certain special properties and application advantages.
VCrAIC MAX phase material
VCrAIC MAX phase material. Purity: 0.99.
Vc-seco-DUBA
Vc-seco-DUBA (Duocarmazine) is a agent-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Duocarmazine. CAS No. 1345681-58-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128957.
VD-846
VD-846 is an antibiotic produced by Streptomyces sp. with activity against gram-positive and -negative bacteria. Synonyms: Antibiotic VD 846 B; VD 846 B. CAS No. 21787-66-6. Molecular formula: C6H4N2O2S2. Mole weight: 200.2.
VDAC1 / Porin + VDAC2 Antibody [F9G1]
Porin,VDAC,VDAC1,VDAC1 / Porin,VDAC1 / Porin + VDAC2. Group: Antibodies. Alternative Names: Porin,VDAC,VDAC1,VDAC1 / Porin + VDAC2. CAS No. Pack Sizes: 20uL. Product ID: F2882. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
VDAC Antibody [D6L19]
Porin,VDAC,VDAC1,VDAC1 / Porin, Plasmalemmal porin, Porin 31HL, Porin 31HM. Group: Antibodies. Alternative Names: Porin,VDAC,VDAC1,VDAC1 / Porin, Plasmalemmal porin, Porin 31HL, Porin 31HM. Pack Sizes: 20ul. Product ID: F0314. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
VDM 11
VDM 11. Group: Biochemicals. Grades: Purified. CAS No. 313998-81-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
VE-821
VE-821 is a potent ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1232410-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14731.
VE-821
VE-821(ATR inhibitor IV) is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays, shows inhibition of H2AX phosphorylation, minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ. Group: Inhibitors. Alternative Names: ATR inhibitor IV. CAS No. 1232410-49-9. Pack Sizes: 10mg. Product ID: S8007. Formula: C18H16N4O3S. Smiles: CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Vebicorvir
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABI-H0731. CAS No. 2090064-66-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-109195.
Vectra LCP
Vectra LCP.
Vecuronium bromide
Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORG NC 45. CAS No. 50700-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0118A.
Vecuronium Bromide
An aminosteroid, competitive neuromuscular blocker agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 50700-72-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Vecuronium Bromide Relate
Vecuronium Bromide Relate. CAS No. 6585-1-3. Product ID: ACM1711166. Alfa Chemistry - ISO 9001:32057 Certified.
Vecuronium Bromide Relate
Vecuronium Bromide Relate. CAS No. 6585-3-2. Product ID: ACM1711224. Alfa Chemistry - ISO 9001:32057 Certified.
Vecuronium bromide Related Compound A
Vecuronium bromide Related Compound A. Uses: For analytical and research use. CAS No. 13529-31-2. Mole weight: 542.79. Catalog: AP13529312.
Vecuronium bromide Related Compound B
Vecuronium bromide Related Compound B. Uses: For analytical and research use. CAS No. 50587-95-6. Mole weight: 595.69. Catalog: AP50587956.
Vecuronium bromide Related Compound C
Vecuronium bromide Related Compound C. Uses: For analytical and research use. CAS No. 73319-30-9. Mole weight: 553.66. Catalog: AP73319309.
Vecuronium bromide Related Compound F
Vecuronium bromide Related Compound F. Uses: For analytical and research use. CAS No. 73319-13-8. Mole weight: 595.69. Catalog: AP73319138.
Vecuronium EP Impurity A (Pancuronium EP Impurity E)
Vecuronium EP Impurity A (Pancuronium EP Impurity E). Uses: For analytical and research use. CAS No. 13529-31-2. Molecular formula: C33H54N2O4. Mole weight: 542.81. Catalog: APB13529312.
Vecuronium EP Impurity B (Pancuronium)
Vecuronium EP Impurity B (Pancuronium). Uses: For analytical and research use. CAS No. 15500-66-0. Molecular formula: C35H60Br2N2O4. Mole weight: 732.68. Catalog: APB15500660.
Vecuronium EP Impurity C
Vecuronium EP Impurity C. Uses: For analytical and research use. CAS No. 73319-13-8. Molecular formula: C32H55BrN2O3. Mole weight: 595.71. Catalog: APB73319138.
Vecuronium EP Impurity D
Vecuronium EP Impurity D. Uses: For analytical and research use. CAS No. 73319-30-9. Molecular formula: C30H53BrN2O2. Mole weight: 553.67. Catalog: APB73319309.
Vecuronium EP Impurity E
Vecuronium EP Impurity E. Uses: For analytical and research use. CAS No. 50587-95-6. Molecular formula: C32H55BrN2O3. Mole weight: 595.71. Catalog: APB50587956.
Vecuronium EP Impurity F
Vecuronium EP Impurity F. Uses: For analytical and research use. CAS No. 18668-29-6. Molecular formula: C26H41NO3. Mole weight: 415.62. Catalog: APB18668296.
Vedaprofen
Propionic acid type non-steroidal anti-inflammatory drug (NSAID). Group: Biochemicals. Grades: Highly Purified. CAS No. 71109-09-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Vedaprofen-d3
Propionic acid type non-steroidal anti-inflammatory drug (NSAID). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Vedaprofen-[d3]
Vedaprofen-[d3] is the labelled analogue of Vedaprofen, which is a propionic acid nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of inflammations and pains. Synonyms: Vedaprofen-D3; 2-(4-Cyclohexylnaphthalen-1-yl)-propionic acid-D3; 4-Cyclohexyl-α-(methyl-d3)-1-naphthaleneacetic Acid; 2-(4-Cyclohexil-1-naphthyl)propionic Acid-d3; Quadrisol-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1185054-34-5. Molecular formula: C19H19D3O2. Mole weight: 285.40.
Vedolizumab
Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human lymphocyte α4β7 integrin, Humanized Antibody; LDP-02; MLN-002. CAS No. 943609-66-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9911.
Vedolizumab (anti-α4β7-integrin)
Vedolizumab (anti-α4β7-integrin) is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 943609-66-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9911A.
Vegan Vitamin D3
Vegan Vitamin D3. CAS No. 67-97-0. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Vegetable glycerol
500ml Pack Size. Group: Analytical Reagents, Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials, Organics, Solvents. Formula: HOCH2CH(OH)CH2OH. CAS No. 56-81-5. Prepack ID 90025553-500ml. Molecular Weight 92.09. See USA prepack pricing.
Vegetable oil
Pale yellow oily liquid with a weak, fatty odor. Floats on water. CAS No. 68956-68-3. Product ID: PE-0275. Category: Plasters Base. Product Keywords: Pharmaceutical Excipients; Semi-solid Dosage Form; Plasters Base; Vegetable oil; PE-0275; 68956-68-3; 68956-68-3. Appearance: Pale yellow oily liquid. EC Number: 273-313-5. Solubility: Insoluble in water.
Vegetable oil
Pale yellow oily liquid with a weak, fatty odor. Floats on water. CAS No. 68956-68-3. Product ID: PE-0172. Category: Filler. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Capsule Excipients; Filler; Vegetable oil; PE-0172; 68956-68-3; 68956-68-3. Appearance: Pale yellow oily liquid. EC Number: 273-313-5. Solubility: Insoluble in water.
Vegetable Oil, Hydrogenated
Hydrogenated vegetable oil is a mixture of triglycerides of fatty acids. The two types that are defined in the USP are characterized by their physical properties. Hydrogenated vegetable oil type I occurs in various forms, e.g.fine powder, flakes, or pellets. The color of the material depends on the manufacturing process and the form. In general, the material is white to yellowish-white with the powder grades appearing more white-colored than the coarser grades. Synonyms: Hydrogenated cottonseed oil: Akofine; Lubritab; Sterotex. CAS No. 68334-00-9. Product ID: PE-0444. Category: Dispersants. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Vegetable Oil, Hydrogenated; Dispersion Excipients; Dispersants; 68334-00-9; 68334-00-9. UNII: NA. Chemical Name: Hydrogenated vegetable oil [68334-00-9]. Hydrogenated soybean oil [8016-70-4]. Grade: Pharmceutical Excipients. Administration route: Oral; rectal and vaginal and topical. Dosage Form: Oral capsules and tablets; rectal and vaginal suppositories and topical preparations. Stability and Storage Conditions: Hydrogenated vegetable oil type I is a stable material; typically it is assigned a 2-year shelf-life. The bulk material should be stored in a well-closed container in a cool, dry place. Source and Preparation: Hydrogenated vegetable oil type I is prepared from refined vegetable oils, which are hydrogenated using a catalyst. App
VEGFR2/KDR Antagonist is a VEGFR2/KDR heptapeptide antagonist that inhibits VEGF binding to KDR and prevents VEGF-induced angiogenesis in vivo. Synonyms: H-Ala-Thr-Trp-Leu-Pro-Pro-Arg-OH. Molecular formula: C40H61N11O9. Mole weight: 840.0.
Vejovine (23-82) is a new type of antibiotic peptide derived from scorpion venom, which shows significant and effective antibacterial activity against clinical isolates of Gram-negative multi-drug resistant strains of Escherichia coli, Pseudomonas aerμginosa and Acinetobacter baumannii. Synonyms: Gly-Ile-Trp-Ser-Ser-Ile-Lys-Asn-Leu-Ala-Ser-Lys-Ala-Trp-Asn-Ser-Asp-Ile-Gly-Gln-Ser-Leu-Arg-Asn-Lys-Ala-Ala-Gly-Ala-Ile-Asn-Lys-Phe-Val-Ala-Asp-Lys-Ile-Gly-Val-Thr-Pro-Ser-Gln-Ala-Ala-Ser-Met-Thr-Leu-Asp-Glu-Ile-Val-Asp-Ala-Met-Tyr-Tyr-Asp.
Veligrotug
Veligrotug (AVE1642) is a selective, fully human IGF-1R antagonist antibody with a Kd value of 0.55 nM for hIGF-1R. Veligrotug blocks the phosphorylation of downstream AKT. Veligrotug is applicable to research related to thyroid eye disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AVE1642; VRDN-001. CAS No. 2728655-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990084.
Veliparib
Veliparib (ABT-888) is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with Kis of 5.2 and 2.9 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-888. CAS No. 912444-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10129.
Veliparib
ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Group: Biochemicals. Alternative Names: 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide; A 861695; ABT 888. Grades: Purified. CAS No. 912444-00-9. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Veliparib (ABT-888)
Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3. Group: Inhibitors. Alternative Names: NSC 737664. CAS No. 912444-00-9. Pack Sizes: 1g. Product ID: S1004. Formula: C13H16N4O. Smiles: CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Vellosimine
Vellosimine is a natural alkaloid found in the herbs of Rauvolfia verticillata. Synonyms: 4-ethyl-4-phenyl-piperidine-2,6-dione; 2,6-Piperidinedione,4-ethyl-4-phenyl. Grade: >95%. CAS No. 6874-98-2. Molecular formula: C19H20N2O. Mole weight: 292.4.
vellosimine dehydrogenase
Also acts on related alkaloids with an endo-aldehyde group as vellosimine (same stereochemistry at C-16) but only slight activity with exo-aldehydes. Detected in many cell suspension cultures of plants from the family Apocynaceae. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.273. CAS No. 86777-26-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0180; vellosimine dehydrogenase; EC 1.1.1.273; 86777-26-6. Cat No: EXWM-0180.
Velneperit
Velneperit (S-2367) is an orally active neuropeptide Y (NPY) Y5 receptor antagonist that can penetrate the blood-brain barrier. Velneperit inhibits the appetite-stimulating and metabolism-inhibiting effects mediated by NPY. Velneperit selectively improves diet-induced obesity in mice. Velneperit enhances the expression of fear acutely by removing the inhibition of CeA Drd2 neurons. Velneperit can be used for the study of obesity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S2367. CAS No. 342577-38-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14423.
Velpatasvir is a complex organic heteropentacyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with sofosbuvir (under the brand name Epclusa) for treatment of patients with chronic hepatitis C of all six major genotypes. It has a role as an antiviral drug and a hepatitis C virus nonstructural protein 5A inhibitor. It is an organic heteropentacyclic compound, a N-acylpyrrolidine, a L-valine derivative, a carbamate ester, a member of imidazoles, a ring assembly and an ether. Category: Antivirus apis. Synonyms: Velpatasvir. Velpatasvir(GS5816). CAS No. 1377049-84-7. Product ID: API1377049847. Molecular formula: C49H54N8O8. Mole weight: 883. EINECS: 806-555-2. SMILES: CC1CCC(N1C(=O)C(C(C)C)NC(=O)OC)C2=NC3=C(N2)C=CC4=CC5=C(C=C43)OCC6=C5C=CC(=C6)C7=CN=C(N7)C8CC(CN8C(=O)C(C9=CC=CC=C9)NC(=O)OC)COC. Appearance: White to Off-white Solid.
Velpatasvir
Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 2.16 μM[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-5816. CAS No. 1377049-84-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12530.
Velpatasvir impurity 1
Velpatasvir impurity 1. Uses: For analytical and research use. CAS No. 1378391-45-7. Molecular formula: C44H53N7O7. Mole weight: 791.95. Catalog: APB1378391457.
Velpatasvir impurity 2
Velpatasvir impurity 2. Uses: For analytical and research use. CAS No. 1844064-96-5. Molecular formula: C39H45N7O5. Mole weight: 691.83. Catalog: APB1844064965.
Velpatasvir impurity 3
Velpatasvir impurity 3. Uses: For analytical and research use. Molecular formula: C50H56N8O8. Mole weight: 897.05. Catalog: APB11928.
Velpatasvir impurity 4
Velpatasvir impurity 4. Uses: For analytical and research use. Molecular formula: C49H54N8O8. Mole weight: 883.02. Catalog: APB11930.
Velpatasvir impurity 5
Velpatasvir impurity 5. Uses: For analytical and research use. Molecular formula: C49H54N8O8. Mole weight: 883.02. Catalog: APB11929.
Velsecorat
AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD7594; AZ13189620. CAS No. 1196509-60-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111453.
Veltuzumab
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody. Veltuzumab has low EC50 value of 0.08-0.09 μg/mL in the Daudi cell line. Veltuzumab can be used for the research of cancer including non-Hodgkin lymphoma (NHL)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMMU-106; hA20. CAS No. 728917-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99224.
Veludacigib
BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 2965501. CAS No. 2732902-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153343.
Velusetrag
Velusetrag (TD-5108) is an orally active, potent and selective agonist of serotonin 5-HT4 receptor (5-HT4R), with a pKi of 7.7. Velusetrag exhibits no affinity (Ki>10 μM) for 5-HT2A and 5-HT2B receptors. Velusetrag can be used for the research of gastrointestinal diseases and Parkinson's disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TD-5108. CAS No. 866933-46-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457.
Velusetrag hydrochloride
Velusetrag (TD-5108) hydrochloride is an orally active, potent and selective agonist of serotonin 5-HT4 receptor (5-HT4R), with a pKi of 7.7. Velusetrag hydrochloride exhibits no affinity (Ki>10 μM) for 5-HT2A and 5-HT2B receptors. Velusetrag hydrochloride can be used for the research of gastrointestinal diseases and Parkinson's disease[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TD-5108 hydrochloride. CAS No. 866933-51-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457A.
Velutin
Velutin is a flavonoid. Velutin can be extracted from mistletoe. Velutin inhibits mushroom Tyrosinase activity with an IC50 of 910.1 μM. Velutin inhibits p38 phosphorylation, the NF-κB pathway and the MAPK pathway. Velutin prevents articular cartilage degeneration and subchondral bone loss. Velutin slows down the progression of intervertebral disc degeneration. Velutin exhibits inhibitory effects on melanogenesis, skin whitening, anti-inflammatory, anti-allergic, anti-oxidant and antibacterial activities. Velutin can be used in studies related to pigmented diseases, osteoarthritis and intervertebral disc degeneration[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 25739-41-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1098.
Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M4205; IDRX-42. CAS No. 2590556-80-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-132166.
Vemircopan
Vemircopan (ALXN2050) is an orally active complement factor D (FD) inhibitor. Vemircopan can be used in the research of diseases such as myasthenia gravis, lupus nephritis, IgA nephropathy, and paroxysmal nocturnal hemoglobinuria[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALXN2050; ACH 0145228; ACH-5228. CAS No. 2086178-00-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139588.
Vemtoberant
Vemtoberant is a β3-adrenergic receptor inhibitor with a human Ki of 8.2 nM, and exhibits 400- to 600-fold selectivity over human β1-AR and β2-AR. Vemtoberant attenuates β3-AR-mediated cardiac inhibition. Vemtoberant can be used for the research of systolic heart failure[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: APD418. CAS No. 2169905-68-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148804.
Vemurafenib
Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLX4032; RG7204; RO5185426. CAS No. 918504-65-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12057.
Vemurafenib
Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma. Category: Active pharmaceutical ingredients. CAS No. 918504-65-1. Product ID: API918504651. Molecular formula: C23H18ClF2N3O3S. Mole weight: 489.92.