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| Product | Description | |
|---|---|---|
| Venetoclax Impurity 21 | Venetoclax Impurity 21. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. Molecular formula: C33H36N4O3. Mole weight: 536.66. Catalog: APB01837. |  |
| Venetoclax Impurity 28 | Venetoclax Impurity 28. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoic acid. CAS No. 2142574-09-0. Molecular formula: C14H9FN2O3. Mole weight: 272.24. Catalog: APB2142574090. | |
| Venetoclax Impurity 3 | Venetoclax Impurity 3. Uses: For analytical and research use. Molecular formula: C45H48ClN7O8S. Mole weight: 882.43. Catalog: APB12384. | |
| Venetoclax Impurity 32 | Venetoclax Impurity 32. Uses: For analytical and research use. Alternative Names: 5-(3-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)phenoxy)-1H-pyrrolo[2,3-b]pyridine. Molecular formula: C32H35ClN4O. Mole weight: 527.11. Catalog: APB01834. | |
| Venetoclax Impurity 35 | Venetoclax Impurity 35. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. CAS No. 2573767-91-4. Molecular formula: C45H51N7O7S. Mole weight: 833.99. Catalog: APB2573767914. | |
| Venetoclax Impurity 37 | Venetoclax Impurity 37. Uses: For analytical and research use. Alternative Names: 4-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. Molecular formula: C33H35ClN4O3. Mole weight: 571.11. Catalog: APB01804. | |
| Venetoclax Impurity 38 | Venetoclax Impurity 38. Uses: For analytical and research use. Alternative Names: 4-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Molecular formula: C45H50ClN7O7S. Mole weight: 868.44. Catalog: APB01803. | |
| Venetoclax Impurity 39 | Venetoclax Impurity 39. Uses: For analytical and research use. Alternative Names: 3-amino-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide. CAS No. 1271003-71-4. Molecular formula: C12H19N3O3S. Mole weight: 285.36. Catalog: APB1271003714. | |
| Venetoclax Impurity 4 | Venetoclax Impurity 4. Uses: For analytical and research use. CAS No. 93745-74-5. Molecular formula: C6H5ClN2O4S. Mole weight: 236.63. Catalog: APB93745745. | |
| Venetoclax Impurity 4 | Venetoclax Impurity 4. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((3-amino-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzamide. Molecular formula: C45H52ClN7O5S. Mole weight: 838.46. Catalog: APB01842. | |
| Venetoclax Impurity 5 (2-chloro-3-nitrobenzenesulfonamide) | Venetoclax Impurity 5 (2-chloro-3-nitrobenzenesulfonamide). Uses: For analytical and research use. CAS No. 1261761-91-4. Molecular formula: C6H5ClN2O4S. Mole weight: 236.63. Catalog: APB1261761914. | |
| Venetoclax Impurity 6 | Venetoclax Impurity 6. Uses: For analytical and research use. Alternative Names: methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoate. CAS No. 1235865-76-5. Molecular formula: C34H37ClN4O3. Mole weight: 585.14. Catalog: APB1235865765. | |
| Venetoclax Impurity 7 | Venetoclax Impurity 7. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. CAS No. 1235865-77-6. Molecular formula: C33H35ClN4O3. Mole weight: 571.11. Catalog: APB1235865776. | |
| Venetoclax Impurity 8 | Venetoclax Impurity 8. Uses: For analytical and research use. Alternative Names: 4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde. CAS No. 1228837-05-5. Molecular formula: C15H17ClO. Mole weight: 248.75. Catalog: APB1228837055. | |
| Venetoclax Impurity 9 | Venetoclax Impurity 9. Uses: For analytical and research use. Alternative Names: (4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol. CAS No. 1228780-51-5. Molecular formula: C15H19ClO. Mole weight: 250.76. Catalog: APB1228780515. | |
| Venetoclax (Standard) | Venetoclax (Standard) is the analytical standard of Venetoclax. This product is intended for research and analytical applications. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-199 (Standard); GDC-0199 (Standard); RG7601 (Standard). CAS No. 1257044-40-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15531R. |  |
| Venlafaxine | Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as the treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It has seemingly superior efficacy in severe depression as a narcotic and is increasingly used as a measure of last resort for refractory cases. Alternative Names: Wy 45030; Wy45030; Wy-45030; Effexor; Elafax. Grades: >98%. CAS No. 93413-69-5. Molecular formula: C17H27NO2. Mole weight: 277.4. |  |
| Venlafaxine | Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Wy 45030. CAS No. 93413-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196. | |
| Venlafaxine Acetamide Impurity | Venlafaxine Acetamide Impurity. Uses: For analytical and research use. CAS No. 295366-48-2. Molecular formula: C17H25NO3. Mole weight: 291.39. Catalog: APB295366482. | |
| Venlafaxine Cyano Impurity | Venlafaxine Cyano Impurity. Uses: For analytical and research use. CAS No. 93413-76-4. Molecular formula: C15H19NO2. Mole weight: 245.32. Catalog: APB93413764. | |
| Venlafaxine cyclic impurity | Venlafaxine cyclic impurity. Group: Biochemicals. Alternative Names: 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane. Grades: Highly Purified. CAS No. 93413-70-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H25NO2. US Biological Life Sciences. |  Worldwide |
| Venlafaxine-[d10] Hydrochloride | One of the isotopic labelled form of Venlafaxine HCl, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Alternative Names: D,L-Venlafaxine-d10 Hydrochloride; 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride-d10. CAS No. 1216539-56-8. Molecular formula: C17H18D10ClNO2. Mole weight: 323.92. | |
| Venlafaxine-[d3] | Labelled Venlafaxine. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. Alternative Names: 1-(2-(dimethylamino)-1-(4-(methoxy-d3)phenyl)ethyl)cyclohexan-1-ol. Grades: >98%. CAS No. 940297-28-9. Molecular formula: C17H24D3NO2. Mole weight: 280.42. | |
| Venlafaxine EP Impurity A | Venlafaxine EP Impurity A. Uses: For analytical and research use. CAS No. 775-33-7. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB775337. | |
| Venlafaxine EP Impurity A HCl | Venlafaxine EP Impurity A HCl. Uses: For analytical and research use. CAS No. 50822-98-5. Molecular formula: C11H18ClNO. Mole weight: 215.72. Catalog: APB50822985. | |
| Venlafaxine EP Impurity A hydrochloride | Venlafaxine EP Impurity A hydrochloride is an impurity of Venlafaxine, which is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. Alternative Names: Descyclohexanol Venlafaxine HCl; 4-Methoxy-N,N-dimethylbenzeneethanamine hydrochloride; p-Methoxy-N,N-dimethyl-phenethylamine hydrochloride; N,N-Dimethyl-2-(p-anisyl)ethylamine hydrochloride; N,N-Dimethyl-4-methoxyphenethylamine hydrochloride; Benzeneethanamine, 4-methoxy-N,N-dimethyl-, hydrochloride (1:1); Venlafaxine Hydrochloride EP Impurity A hydrochloride; Phenethylamine, p-methoxy-N,N-dimethyl-, hydrochloride; 4-Methoxy-N,N-dimethylphenethylamine hydrochloride; [2-(4-Methoxyphenyl)ethyl]dimethylamine hydrochloride; p-Methoxy-N,N-dimethylphenethylamine hydrochloride; 2-(4-Methoxyphenyl)-N,N-dimethylethylamine hydrochloride. Grades: ≥95%. CAS No. 50822-98-5. Molecular formula: C11H17NO.HCl. Mole weight: 215.72. | |
| Venlafaxine EP Impurity B | Venlafaxine EP Impurity B. Uses: For analytical and research use. CAS No. 323176-93-8. Molecular formula: C14H21NO3. Mole weight: 251.33. Catalog: APB323176938. | |
| Venlafaxine EP Impurity B HCl | Venlafaxine EP Impurity B HCl. Uses: For analytical and research use. CAS No. 2174001-92-2. Molecular formula: C14H22ClNO3. Mole weight: 287.78. Catalog: APB2174001922. | |
| Venlafaxine EP Impurity C | Venlafaxine EP Impurity C. Uses: For analytical and research use. CAS No. 93413-77-5. Molecular formula: C15H23NO2. Mole weight: 249.35. Catalog: APB93413775. | |
| Venlafaxine EP Impurity C HCl | Venlafaxine EP Impurity C HCl. Uses: For analytical and research use. CAS No. 130198-05-9. Molecular formula: C15H24ClNO2. Mole weight: 285.81. Catalog: APB130198059. | |
| Venlafaxine EP Impurity D | Venlafaxine EP Impurity D. Uses: For analytical and research use. CAS No. 149289-30-5. Molecular formula: C16H25NO2. Mole weight: 263.38. Catalog: APB149289305. | |
| Venlafaxine EP Impurity D HCl | Venlafaxine EP Impurity D HCl. Uses: For analytical and research use. CAS No. 93413-90-2. Molecular formula: C16H26ClNO2. Mole weight: 299.84. Catalog: APB93413902. | |
| Venlafaxine EP Impurity E | Venlafaxine EP Impurity E. Uses: For analytical and research use. CAS No. 93413-70-8. Molecular formula: C17H25NO2. Mole weight: 275.39. Catalog: APB93413708. | |
| Venlafaxine EP Impurity E HCl | Venlafaxine EP Impurity E HCl. Uses: For analytical and research use. CAS No. 93413-56-0. Molecular formula: C17H26ClNO2. Mole weight: 311.85. Catalog: APB93413560. | |
| Venlafaxine EP Impurity F | Venlafaxine EP Impurity F. Uses: For analytical and research use. CAS No. 93413-57-1. Molecular formula: C17H25NO. Mole weight: 259.39. Catalog: APB93413571. | |
| Venlafaxine EP Impurity F HCl | Venlafaxine EP Impurity F HCl. Uses: For analytical and research use. CAS No. 93413-79-7. Molecular formula: C17H26ClNO. Mole weight: 295.85. Catalog: APB93413797. | |
| Venlafaxine EP Impurity G | Venlafaxine EP Impurity G. Uses: For analytical and research use. CAS No. 1076199-92-2. Molecular formula: C17H27NO. Mole weight: 261.41. Catalog: APB1076199922. | |
| Venlafaxine EP Impurity G HCl | Venlafaxine EP Impurity G HCl. Uses: For analytical and research use. CAS No. 2108968-20-1. Molecular formula: C17H28ClNO. Mole weight: 297.87. Catalog: APB2108968201. | |
| Venlafaxine EP Impurity H | Venlafaxine EP Impurity H. Uses: For analytical and research use. CAS No. 1329795-88-1. Molecular formula: C24H33NO3. Mole weight: 383.53. Catalog: APB1329795881. | |
| Venlafaxine EP Impurity H HCl | Venlafaxine EP Impurity H HCl. Uses: For analytical and research use. Molecular formula: C24H34ClNO3. Mole weight: 419.99. Catalog: APB10051. | |
| Venlafaxine hydrochloride | Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. Uses: Antidepressant. Alternative Names: Wy-45030; Wy45030; Wy 45030; Effexor hydrochloride; Effexor; VENLAFAXINE HCl; Effexor XR; Trevilor. Grades: >98%. CAS No. 99300-78-4. Molecular formula: C17H28ClNO2. Mole weight: 313.86. | |
| Venlafaxine hydrochloride | Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Wy 45030 hydrochloride. CAS No. 99300-78-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-B0196A. | |
| Venlafaxine hydrochloride | Venlafaxine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 99300-78-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Venlafaxine Impurity 10 | Venlafaxine Impurity 10. Uses: For analytical and research use. CAS No. 93413-61-7. Molecular formula: C23H31NO2. Mole weight: 353.51. Catalog: APB93413617. | |
| Venlafaxine Impurity 11 | Venlafaxine Impurity 11. Uses: For analytical and research use. CAS No. 29903-09-1. Molecular formula: C17H18O3. Mole weight: 270.33. Catalog: APB29903091. | |
| Venlafaxine Impurity 12 | Venlafaxine Impurity 12. Uses: For analytical and research use. CAS No. 1346601-14-6. Molecular formula: C25H35NO3. Mole weight: 397.56. Catalog: APB1346601146. | |
| Venlafaxine Impurity 13 | Venlafaxine Impurity 13. Uses: For analytical and research use. CAS No. 1346605-18-2. Molecular formula: C16H25NO. Mole weight: 247.38. Catalog: APB1346605182. | |
| Venlafaxine Impurity 15 | Venlafaxine Impurity 15. Uses: For analytical and research use. CAS No. 1643948-40-6. Molecular formula: C17H25NO3. Mole weight: 291.39. Catalog: APB1643948406. | |
| Venlafaxine Impurity 19 | Venlafaxine Impurity 19. Uses: For analytical and research use. CAS No. 727728-51-0. Molecular formula: C16H23NO2. Mole weight: 261.37. Catalog: APB727728510. | |
| Venlafaxine Impurity 20 | Venlafaxine Impurity 20. Uses: For analytical and research use. Molecular formula: C15H23NO. Mole weight: 233.36. Catalog: APB10052. | |
| Venlafaxine Impurity 21 | Venlafaxine Impurity 21. Uses: For analytical and research use. CAS No. 272788-07-5. Molecular formula: C16H23NO3. Mole weight: 277.36. Catalog: APB272788075. | |
| Venlafaxine Impurity 39 | Venlafaxine Impurity 39. Uses: For analytical and research use. CAS No. 448904-47-0. Molecular formula: C20H31NO6. Mole weight: 381.47. Catalog: APB448904470. | |
| Venlafaxine Impurity 40 | Venlafaxine Impurity 40. Uses: For analytical and research use. CAS No. 1062606-12-5. Molecular formula: C17H22D6ClNO2. Mole weight: 319.9. Catalog: APB1062606125. | |
| Venlafaxine Impurity 41 | Venlafaxine Impurity 41. Uses: For analytical and research use. CAS No. 2680662-11-5. Molecular formula: C16H24N2O3. Mole weight: 292.38. Catalog: APB2680662115. | |
| Venlafaxine Impurity 5 | Venlafaxine Impurity 5. Uses: For analytical and research use. CAS No. 1346600-77-8. Molecular formula: C13H19NO3. Mole weight: 237.3. Catalog: APB1346600778. | |
| Venlafaxine N-Oxide | Venlafaxine N-Oxide is a prodrug. Group: Biochemicals. Alternative Names: 1-[2- (Dimethyloxidoamino) -1- (4-methoxyphenyl) ethyl]cyclohexanol. Grades: Highly Purified. CAS No. 1094598-37-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Venlafaxine Related Compound A | Venlafaxine Related Compound A. Uses: For analytical and research use. CAS No. 93413-90-2. Mole weight: 299.84. Catalog: AP93413902. | |
| Venom antimicrobial peptide-6 | Venom antimicrobial peptide-6 is an antimicrobial peptide from Mesobuthus eupeus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Meucin-13; Ile-Phe-Gly-Ala-Ile-Ala-Gly-Leu-Leu-Lys-Asn-Ile-Phe-NH2. Molecular formula: C68H110N16O14. Mole weight: 1375.73. | |
| Venom antimicrobial peptide-9 | Venom antimicrobial peptide-9 is an antimicrobial peptide from Mesobuthus eupeus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: meucin-18; Phe-Phe-Gly-His-Leu-Phe-Lys-Leu-Ala-Thr-Lys-Ile-Ile-Pro-Ser-Leu-Phe-Gln. | |
| venombin A | A somewhat thrombin-like enzyme from venoms of snakes of the viper/rattlesnake group. Species variants of the enzyme include ancrod from Agkistrodon rhodostoma (Malayan pit viper) (formerly EC 3.4.21.28), batroxobin from Bothrops atrox (South American pit viper) (formerly EC 3.4.21.29) and crotalase from Crotalus adamanteus (Eastern diamondback rattlesnake) (formerly EC 3.4.21.30). In peptidase family S1 (trypsin family). Does not require activation by Ca2+. Group: Enzymes. Synonyms: α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Enzyme Commission Number: EC 3.4.21.74. CAS No. 146240-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4166; venombin A; EC 3.4.21.74; 146240-35-9; α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Cat No: EXWM-4166. |  |
| venombin AB | From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin. Group: Enzymes. Synonyms: gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Enzyme Commission Number: EC 3.4.21.55. CAS No. 104003-74-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4147; venombin AB; EC 3.4.21.55; 104003-74-9; gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Cat No: EXWM-4147. | |
| venom exonuclease | Preference for single-stranded substrate. Group: Enzymes. Synonyms: venom phosphodiesterase. Enzyme Commission Number: EC 3.1.15.1. CAS No. 9025-82-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3542; venom exonuclease; EC 3.1.15.1; 9025-82-5; venom phosphodiesterase. Cat No: EXWM-3542. | |
| Venturicidin A | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Alternative Names: Aabomycin A1. Grades: >95% by HPLC. CAS No. 33538-71-5. Molecular formula: C41H67NO11. Mole weight: 749.97. | |
| Venturicidin A | Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aabomycin A1. CAS No. 33538-71-5. Pack Sizes: 1 mg. Product ID: HY-N125722. | |
| Venturicidin B | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Alternative Names: Aabomycin A2; (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one. Grades: >95% by HPLC. CAS No. 33538-72-6. Molecular formula: C40H66O10. Mole weight: 706.94. | |
| Vepafestinib | Vepafestinib (TAS0953/HM06) is a next-generation brain-penetrant, selective and orally active RET inhibitor with an IC50 value of 0.33 nM. Vepafestinib inhibits the phosphorylation of RET and its downstream signaling pathways, thus blocking the growth and signal transduction of tumor cells and inducing cell cycle arrest and apoptosis. Vepafestinib can be used in the research of various RET-driven cancers, such as non-small cell lung cancer, thyroid cancer and other disease areas[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAS0953/HM06. CAS No. 2129515-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132846. | |
| Vepdegestrant | Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC50) of about 2 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARV-471. CAS No. 2229711-68-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138642. | |
| VER 155008 | VER 155008. Group: Biochemicals. Grades: Purified. CAS No. 1134156-31-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VER-155008 | VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70. Uses: Scientific research. Category: Signaling pathways. CAS No. 1134156-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10941. | |
| VER-155008 | VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Alternative Names: 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine; C07; VER 155008; VER155008; 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-Adenosine; 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile. Grades: ≥95%. CAS No. 1134156-31-2. Molecular formula: C25H23Cl2N7O4. Mole weight: 556.40. | |
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