A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Acteoside. Product Category: Inhibitors. CAS No. 61276-17-3. Molecular formula: C29H36O15. Mole weight: 624.59. Purity: 98%+. IUPACName: Verbascoside. Density: 1.6 g/cm³. Product ID: ACM61276173. Alfa Chemistry ISO 9001:2015 Certified.
Verbenalin
Cornin has protective potential against cerebral ischemia injury and its protective effects may be due to amelioration of cerebral mitochondrial function and its antioxidant property. Synonyms: cornin; methyl (1S,4aS,7S,7aR)-1-(beta-D-glucopyranosyloxy)-7-methyl-5-oxo-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate. Grade: >98%. CAS No. 548-37-8. Molecular formula: C17H24O10. Mole weight: 388.37.
Verbenalin
Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 548-37-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2014.
Verbenalin (Verbenaloside, Cornin)
Verbenalin (Verbenaloside, Cornin). Group: Biochemicals. Alternative Names: Verbenaloside; Cornin. Grades: Plant Grade. CAS No. 548-37-8. Pack Sizes: 10mg. Molecular Formula: C17H24O10, Molecular Weight: 388.365999999999. US Biological Life Sciences.
Worldwide
Verbenone
Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis [1]. Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Verbenone. CAS No. 1196-01-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N6661.
Vercirnon
Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 ?M for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1605786; CCX282-B; Traficet-EN. CAS No. 698394-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15724.
Verdalia A
Verdalia A. CAS No. 53018-24-9. VIGON Item # 503255. Categories: Speciality Ingrdients Suppliers, tropical indene, Fragrances, Perfumers.
America & Internationally
Verdamycin
It is produced by the strain of Micromonospora grisea. Verdamycin has anti-bacterial effect. In in vivo test of mice, it has protective effect on the infection of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus. Synonyms: Verdamicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6-)-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-threo-hept-4-enopyranosyl-(1-4))-2-deoxy-D-streptamine. Grade: 98%. CAS No. 49863-48-1. Molecular formula: C20H39N5O7. Mole weight: 461.55.
Verdinexor
Verdinexor(KPT-335) is a novel, orally bioavailable selective inhibitor of nuclear export (SINE), inhibits nuclear export protein Exportin 1(XPO1/CRM1) against canine tumor cell lines; also reduce influenza virus replication in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-335. CAS No. 1392136-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15970.
Verdiperstat
Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC 50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3241. CAS No. 890655-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17646.
Verekitug is an anti- CRLF2 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2768386-15-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990774.
Vericiguat
Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1021189. CAS No. 1350653-20-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16774.
Verinurad
Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC 50 of 25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA3170. CAS No. 1352792-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16733.
Verinurad Impurity4
Verinurad Impurity4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 125305-75-1. Molecular formula: C9H11NO2S. Mole weight: 197.25. Catalog: APB125305751.
Verinurad Impurity5
Verinurad Impurity5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1016858-18-6. Molecular formula: C8H6N2O2S. Mole weight: 194.21. Catalog: APB1016858186.
Verinurad Impurity9
Verinurad Impurity9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1019535-82-0. Molecular formula: C10H9NO2S. Mole weight: 207.25. Catalog: APB1019535820.
Verlamelin
It is a depsipeptide antibiotic produced by the strain of Fungi MF 4683. It has anti-fungal activity against plant pathogens. Synonyms: MSD-A-43F; Verlamelin; A-43F; Antibiotic MSD-A-43F; Antibiotic A-43F; Cyclo[D-Tyr-5-L-Val-oxytetradecanoyl-D-aThr-D-Ala-L-Pro-L-Glu(NH2)-]. CAS No. 74758-64-8. Molecular formula: C45H71N7O11. Mole weight: 886.09.
Verlukast
A receptor antagonist for the treatment of respiratory diseases. Group: Biochemicals. Alternative Names: 3- [ [ (R) - [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] [ [3- (dimethylamino) -3-oxopropyl] thio] methyl] thio] -propanoic Acid; L 668019; MK 679; R-(-)-MK 571. Grades: Highly Purified. CAS No. 120443-16-5. Pack Sizes: 5mg, 10mg. US Biological Life Sciences.
Worldwide
Verlukast-d6
A receptor antagonist for the treatment of respiratory diseases. Group: Biochemicals. Alternative Names: 3- [ [ (R) - [3- [ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl] phenyl] [ [3- (di (methyl-d3) amino) -3-oxopropyl] thio] methyl] thio] -propanoic Acid; L 668019-d6; MK 679-d6; R-(-)-MK 571-d6. Grades: Highly Purified. CAS No. 153698-86-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Verlukast-[d6]
Verlukast-[d6]. Uses: A receptor antagonist for the treatment of respiratory diseases. Synonyms: Verlukast D6. Grade: 95% atom D. CAS No. 153698-86-3. Molecular formula: C26H21D6ClN2O3S2. Mole weight: 521.12.
Vermiculine
Vermiculine is produced by the strain of Pen. vermiculatum CCM-F-2. It has anti-protozoal and anti-tumor effects, and it also has a less potent effect against gram-positive bacteria. Synonyms: Vermiculin; NSC657321; (-)-Vermiculine; 1,11-diene-2,5,10,13-tetrone,8,16-bis(2-oxopropyl)-, (3E,8S,11E,16S)-. CAS No. 37244-00-1. Molecular formula: C20H24O8. Mole weight: 392.40.
Vermistatin
It is a new metabolite from mine-dwelling Penicillium vermiculatum. It is an antibiotic with cytotoxic effects. Synonyms: (R,E)-4,6-dimethoxy-3-(4-oxo-6-(prop-1-en-1-yl)-4H-pyran-3-yl)isobenzofuran-1(3H)-one; Fijiensin; (-)-Fijiensin; NSC 656107; 1(3H)-Isobenzofuranone, 4,6-dimethoxy-3-(4-oxo-6-(1-propenyl)-4H-pyran-3-yl)-, (R)-; 5-(4,6-Dimethoxy-3R-phthalidy)-2-(1E)-propenyl-4H-pyran-4-one. CAS No. 72669-21-7. Molecular formula: C18H16O6. Mole weight: 328.32.
Vernakalant Hydrochloride
Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na + and atria-preferred K + channel blocker. IC 50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channel wt , Kv1.5 channel I508F , Kv1.5 channel T479A , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSD1235 hydrochloride. CAS No. 748810-28-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14183.
Vernaldehyde ®
Vernaldehyde ®. CAS No. 66327-54-6. Kosher: Y. VIGON Item # 500415. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
Vernamycin B
Vernamycin B is originally isolated from Str. loidensis. Vernamycin B has an antimicrobial effect, but is less effective against gram-negative bacteria and mycobacteria. CAS No. 9040-14-6. Molecular formula: C62H85N7O16S. Mole weight: 1216.44.
Verosudil
Verosudil (AR-12286) is a ROCK inhibitor. Verosudil has equal inhibitory activity against ROCK1 and ROCK2 (Ki: 2 nM). Verosudil is less selective for PKA, PKCT, MRCKA, and CAM2A (Ki: 69 nM, 9322 nM, 28 nM, 5855 nM, respectively). Verosudil increases trabecular outflow capacity to reduce intraocular pressure. Verosudil is useful in the study of glaucoma and ocular hypertension[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-12286. CAS No. 1414854-42-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16758.
Verrucarin A
Verrucarin A (Muconomycin A), a Type D macrocyclic mycotoxin derived from the pathogen fungus Myrothecium verrucaria , is an inhibitor of protein synthesis. Verrucarin A inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Muconomycin A. CAS No. 3148-9-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107426.
Verrucarin A
It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin A has the effect of anti-Gram-negative bacteria and fungi, inhibiting Newcastle disease virus, tobacco Mosaic virus, and S-37 sarcoma and Yoshida sarcoma in animals. Synonyms: Muconomycin A; Antibiotic 379Y; VER A; (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione; NSC 126728. Grade: 95%. CAS No. 3148-9-2. Molecular formula: C27H34O9. Mole weight: 502.55.
It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin B has an effect on Ascites carcinoma, also has a weak inhibitory effect on fungi. Synonyms: (2'S,3'R)-2'-Deoxy-2',3'-oxyverrucarin A. CAS No. 2290-11-1. Molecular formula: C27H32O9. Mole weight: 500.54.
Verrucarin J
Verrucarin J is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin J on giant cell tumor P-815 cells was about 0.001 μg/mL. Uses: For research used only. Synonyms: Muconomycin B; 2',3'-Didehydro-2'-deoxyverrucarin A; Verrucarin A, 2',?3'-didehydro-2'-deoxy-, (2'E)?-; Verrucrin J; Verrucosporin J. Grade: ≥98%. CAS No. 4643-58-7. Molecular formula: C27H32O8. Mole weight: 484.54.
Verrucarin J
Verrucarin J (Muconomycin B) is a metabolite of the Myrothecium fungus family. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Muconomycin B. Product Category: Inhibitors. Appearance: Solid. CAS No. 4643-58-7. Molecular formula: C27H32O8. Mole weight: 484.5. Purity: 95%+. IUPACName: (1R,3R,8R,12E,18E,20Z,24R,25S,26S)-5,13,25-Trimethylspiro[2,10,16,23-tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa-4,12,18,20-tetraene-26,2'-oxirane]-11,17,22-trione. Canonical SMILES: CC1=C[C@@H]2[C@]3(COC(/C=C(C)/CCOC(/C=C/C=C\C(OC4[C@]3(C)[C@@]5([C@H](O2)C4)CO5)=O)=O)=O)CC1. Product ID: ACM4643587-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Verrucarin A.
Verrucarin K
Verrucarin K is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin K on giant cell tumor P-815 cells was about 0.001 μg/mL. Synonyms: BRN 1276841; Verrucarin A, 12,13-deepoxy-12,13-didehydro-. CAS No. 63739-93-5. Molecular formula: C27H34O8. Mole weight: 486.55.
Verrucofortine
A diketopiperazine alkaloid derived from tryptophan and leucine. It is a fungal metabolite isolated from penicillium verrucosum. It exhibits no apparent toxicity in mice even at high doses in vivo. Synonyms: Fructigenine B; Verrucosine; Verrucozine; (-)-Verrucofortine; (3S-(3alpha,5aalpha,10balpha,11abeta))-6-Acetyl-10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione; (3S,5aR,10bR,11aS)-6-acetyl-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grade: >99% by HPLC. CAS No. 113706-21-1. Molecular formula: C24H31N3O3. Mole weight: 409.52.
Verrucofortine is an alkaloidal diketopiperazine derived from tryptophan and leucine isolated from Penicillium species. There are no reports of intensive investigation of verrucofortine. In vivo, mice showed no apparent toxic effects at high doses. Group: Biochemicals. Alternative Names: Fructigenine B, Verrucosine, Verrucozine. Grades: Highly Purified. CAS No. 113706-21-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Verruculogen
Verruculogen is a tremorgenic mycotoxin first isolated from Penicillium verruculosum in 1972 and the structure resolved as an indole alkaloid in 1974. Subsequent investigations have shown that verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic marker. The tremorgenic action of verruculogen is complex but is associated with increases in spontaneous glutamate and aspartate release, decreases in GABA levels and, at toxic doses, an increase in the number and decrease in the affinity of DHP receptors in rat cortex. In in vitro guinea pig ileum preparations, verruculogen causes an increase in contractile responses due to electrical field stimulation, attributed to enhancement of acetylcholine from presynaptic nerve terminals. Verruculogen also inhibits Ca2+-activated K+ channels and is a cell cycle inhibitor blocking division at the M phase. Group: Biochemicals. Grades: Highly Purified. CAS No. 12771-72-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Verruculogen
Verruculogen is a tremorgenic mycotoxin isolated from penicillium verruculosu. It can inhibit the K+ channel activated by ca2+, and is a cell cycle inhibitor that prevents M phase division. Synonyms: TR 1 toxin. Grade: >95% by HPLC. CAS No. 12771-72-1. Molecular formula: C27H33N3O7. Mole weight: 511.57.
Verruculogen (NA 209A, TR 1)
Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has apoptotic effects on human T lymphocytes. Stimulates the growth of seedling roots of buckwheat. Group: Biochemicals. Alternative Names: (5R, 10S, 10aR) -1, 10, 10a, 14, 14aS, 15bS-hexahydro-10, 10a-dihydroxy-7-methoxy-2, 2-dimethyl-5- (2-methyl-1-propen-1-yl) -5H, 12H-3, 4-dioxa-5a, 11a, 15a-triazacyclooct [lm]indeno [5, 6-b]fluorene-11, 15 (2H, 13H) -dione. Grades: Highly Purified. CAS No. 12771-72-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H33N3O7. US Biological Life Sciences.
Worldwide
verruculogen prenyltransferase
Found in a number of fungi. Catalyses the last step in the biosynthetic pathway of the indole alkaloid fumitremorgin A. The enzyme from the fungus Neosartorya fischeri is also active with fumitremorgin B and 12α,13α-dihydroxyfumitremorgin C. Group: Enzymes. Synonyms: FtmPT3. Enzyme Commission Number: EC 2.5.1.107. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2723; verruculogen prenyltransferase; EC 2.5.1.107; FtmPT3. Cat No: EXWM-2723.
verruculogen synthase
Requires Fe2+ and ascorbate. Found in the fungus Aspergillus fumigatus. Both atoms of a dioxygen molecule are incorporated into verruculogen. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A. Group: Enzymes. Synonyms: fmtF (gene name); FmtOx1. Enzyme Commission Number: EC 1.14.11.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0656; verruculogen synthase; EC 1.14.11.38; fmtF (gene name); FmtOx1. Cat No: EXWM-0656.
versatile peroxidase
A hemoprotein. This ligninolytic peroxidase combines the substrate-specificity characteristics of the two other ligninolytic peroxidases, EC 1.11.1.13, manganese peroxidase and EC 1.11.1.14, lignin peroxidase. Unlike these two enzymes, it is also able to oxidize phenols, hydroquinones and both low- and high-redox-potential dyes, due to a hybrid molecular architecture that involves multiple binding sites for substrates. Group: Enzymes. Synonyms: VP; hybrid peroxidase; polyvalent peroxidase; reactive-black-5:hydrogen-peroxide oxidoreductase. Enzyme Commission Number: EC 1.11.1.16. CAS No. 42613-30-9, 114995-15-2. Versatile Peroxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0497; versatile peroxidase; EC 1.11.1.16; 42613-30-9, 114995-15-2; VP; hybrid peroxidase; polyvalent peroxidase; reactive-black-5:hydrogen-peroxide oxidoreductase. Cat No: EXWM-0497.
Versicolin
Versicolin is originally isolated from Asp. versicolor. It only has antibacterial effect on filamentous fungi, and has no inhibitory effect on yeast-like fungi and bacteria. Synonyms: 2,3,6-Trihydroxytoluene; Toluene-2,3,6-triol; BRN 2249549; 1-methyl-2,3,6-trihydroxybenzene. CAS No. 4389-44-0. Molecular formula: C7H8O3. Mole weight: 140.14.
Versicolorin A
Versicolorin A is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione; NSC 274542; (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione. Grade: 98%. CAS No. 6807-96-1. Molecular formula: C18H10O7. Mole weight: 338.27.
Versicolorin B
Versicolorin B is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: (3aS,12aR)-4,6,8-trihydroxy-2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione; Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 2,3,3a,12a-tetrahydro-4,6,8-trihydroxy-, cis-(+-)-. CAS No. 4331-22-0. Molecular formula: C18H12O7. Mole weight: 340.28.
versicolorin B synthase
Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: versiconal cyclase; VBS. Enzyme Commission Number: EC 4.2.1.143. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4984; versicolorin B synthase; EC 4.2.1.143; versiconal cyclase; VBS. Cat No: EXWM-4984.
versiconal hemiacetal acetate esterase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA esterase. Enzyme Commission Number: EC 3.1.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3523; versiconal hemiacetal acetate esterase; EC 3.1.1.94; VHA esterase. Cat No: EXWM-3523.
versiconal hemiacetal acetate reductase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Enzyme Commission Number: EC 1.1.1.353. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0269; versiconal hemiacetal acetate reductase; EC 1.1.1.353; VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Cat No: EXWM-0269.
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis [1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL 318952. CAS No. 129497-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0146.
Verteporfin
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Verteprofin; Verteporphin; trans-3,4-Dicarboxy-4,4a-dihydro-4a,8,14,19-tetramethyl-18-vinyl-23H,25H-benzo(b)porphine-9,13-dipropionic acid 3,4,9-trimethyl ester; Visudyne; VERTEPORFIN (200 MG). Product Category: Inhibitors. Appearance: Powder. CAS No. 129497-78-5. Molecular formula: C41H42N4O8. Mole weight: 1437.61. Purity: 0.95. IUPACName: Verteporfin. Canonical SMILES: C[C@]1(/C2=C/C(N3)=C4C)C(C(/C=C(C(C)=C/5C=C)\NC5=C/C6=N/C(C(CCC(OC)=O)=C6C)=C\C3=C4CCC(O)=O)=N2)=CC=C(C(OC)=O)[C@H]1C(OC)=O.C[C@]7(/C8=C/C(N9)=C%10C)C(C(/C=C(C(C)=C/%11C=C)\NC%11=C/C%12=N/C(C(CCC(O)=O)=C%12C)=C\C9=C%10CCC(OC)=O)=N8)=CC=C(C(OC)=O)[C@H]7C(OC)=O. Product ID: ACM129497785-1. Alfa Chemistry ISO 9001:2015 Certified.
Verteporfin
Verteporfin. Group: Biochemicals. Alternative Names: CL 318952; Visudyne; (4R,4aS)-rel-24H,26H-Benzo[b]porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-monomethyl Ester. Grades: Highly Purified. CAS No. 129497-78-5. Pack Sizes: 10mg. Molecular Formula: C41H44N4O9, Molecular Weight: 736.81. US Biological Life Sciences.
Worldwide
Verteporfin Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Verticillin A
Verticillin A is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, (3S,3'S,5aR,5'aR,10bS,10'bS,11S,11'S,11aS,11'aS)-; [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, [3S-[3α,5aβ,10bβ(3'R*,5'aS*,10'bR*,11'R*,11'aR*),11β,11aα]]-; Verticillin A, (+)-; (6S,6'S)-19,19'-Dideoxy-6,6'-dihydroxychetocin. CAS No. 889640-30-6. Molecular formula: C30H28N6O6S4. Mole weight: 696.84.
Verticillin B
Verticillin B is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: (6S,6'S)-19-Deoxy-6,6'-dihydroxychetocin. CAS No. 52212-86-9. Molecular formula: C30H28N6O7S4. Mole weight: 712.84.
Verticillin C
Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: Verticillin C. Grade: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90.
Vertimycin
It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Synonyms: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19.
Vertisporin
It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Synonyms: Spiro[4H-3a,22-(epoxyethano)-10,12-methano-17H,18H-furo[2',3':10,11][1,6]dioxacyclohexadecino[3,4-d][1]benzopyran-11(12H),2'-oxirane]-8,20(5H,22aH)-dione,2,3,10,10a,13a,16-hexahydro-2,3-dihydroxy-10a,15-dimethyl-, (2R,2'S,3R,3aR,6Z,10R,10aS,12R,13aR,17aR,21E,21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59.
Verubecestat
Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759.
Verubecestat TFA
Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; Verubecestat TFA. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 2095432-65-6. Molecular formula: C19H18F5N5O5S. Mole weight: 523.44. Purity: >98%. IUPACName: (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide trifluoroacetic acid. Canonical SMILES: O=C(NC1=CC=C(F)C([C@@](C2)(C)N=C(N)N(C)S2(=O)=O)=C1)C3=NC=C(F)C=C3.O=C(O)C(F)(F)F. Product ID: ACM2095432656. Alfa Chemistry ISO 9001:2015 Certified.
Verucopeptin
It is an antibiotic produced by the strain of Actinomadura verrucosospora Q886-2. It has weak antimicrobial effect and can prolong the survival time of mice transplanted with melanoma. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Synonyms: 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide. Grade: 98%. CAS No. 138067-14-8. Molecular formula: C43H73N7O13. Mole weight: 896.08.
very-long-chain 3-oxoacyl-CoA reductase
The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. The enzyme is active with substrates with chain length of C16 to C34, depending on the species. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Enzyme Commission Number: EC 1.1.1.330. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0244; very-long-chain 3-oxoacyl-CoA reductase; EC 1.1.1.330; very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Cat No: EXWM-0244.
very-long-chain 3-oxoacyl-CoA synthase
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids. For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate, while CER6 from the same plant prefers substrates with chain length of C22 to C32. cf. EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA. Enzyme Commission Number: EC 2.3.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2142; very-long-chain 3-oxoacyl-CoA synthase; EC 2.3.1.199; very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA synthase; condensing enzyme (ambiguous); CUT1 (gene name); CER6 (gene name); FAE1 (gene name); KCS (gene name); ELO (gene name). Cat No: EXWM-2142.
This is the third component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: PHS1 (gene name); PAS2 (gene name). Enzyme Commission Number: EC 4.2.1.134. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4975; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; EC 4.2.1.134; PHS1 (gene name); PAS2 (gene name). Cat No: EXWM-4975.
very-long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme is most active toward long-chain acyl-CoAs such as C14, C16 and C18, but is also active with very-long-chain acyl-CoAs up to 24 carbons. It shows no activity for substrates of less than 12 carbons. Its specific activity towards palmitoyl-CoA is more than 10-fold that of the long-chain acyl-CoA dehydrogenase. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.8, long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: ACADVL (gene name). Enzyme Commission Number: EC 1.3.8.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1416; very-long-chain acyl-CoA dehydrogenase; EC 1.3.8.9; ACADVL (gene name). Cat No: EXWM-1416.
very-long-chain enoyl-CoA reductase
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase. Group: Enzymes. Synonyms: TSC13 (gene name); CER10 (gene name). Enzyme Commission Number: EC 1.3.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1363; very-long-chain enoyl-CoA reductase; EC 1.3.1.93; TSC13 (gene name); CER10 (gene name). Cat No: EXWM-1363.
Vesatolimod
Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC 50 of 291 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9620. CAS No. 1228585-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15601.
Vesencumab
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MNRP-1685A. CAS No. 1205533-60-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99386.