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Venetoclax Impurity 35. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. CAS No. 2573767-91-4. Molecular formula: C45H51N7O7S. Mole weight: 833.99. Catalog: APB2573767914.
Venetoclax Impurity 37
Venetoclax Impurity 37. Uses: For analytical and research use. Alternative Names: 4-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. Molecular formula: C33H35ClN4O3. Mole weight: 571.11. Catalog: APB01804.
Venetoclax Impurity 38
Venetoclax Impurity 38. Uses: For analytical and research use. Alternative Names: 4-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-2-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. Molecular formula: C45H50ClN7O7S. Mole weight: 868.44. Catalog: APB01803.
Venetoclax Impurity 39
Venetoclax Impurity 39. Uses: For analytical and research use. Alternative Names: 3-amino-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)benzenesulfonamide. CAS No. 1271003-71-4. Molecular formula: C12H19N3O3S. Mole weight: 285.36. Catalog: APB1271003714.
Venetoclax Impurity 4
Venetoclax Impurity 4. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((3-amino-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzamide. Molecular formula: C45H52ClN7O5S. Mole weight: 838.46. Catalog: APB01842.
Venetoclax Impurity 4
Venetoclax Impurity 4. Uses: For analytical and research use. CAS No. 93745-74-5. Molecular formula: C6H5ClN2O4S. Mole weight: 236.63. Catalog: APB93745745.
Venetoclax Impurity 5 (2-chloro-3-nitrobenzenesulfonamide). Uses: For analytical and research use. CAS No. 1261761-91-4. Molecular formula: C6H5ClN2O4S. Mole weight: 236.63. Catalog: APB1261761914.
Venetoclax Impurity 6
Venetoclax Impurity 6. Uses: For analytical and research use. Alternative Names: methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoate. CAS No. 1235865-76-5. Molecular formula: C34H37ClN4O3. Mole weight: 585.14. Catalog: APB1235865765.
Venetoclax Impurity 7
Venetoclax Impurity 7. Uses: For analytical and research use. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. CAS No. 1235865-77-6. Molecular formula: C33H35ClN4O3. Mole weight: 571.11. Catalog: APB1235865776.
Venetoclax Impurity 8
Venetoclax Impurity 8. Uses: For analytical and research use. Alternative Names: 4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde. CAS No. 1228837-05-5. Molecular formula: C15H17ClO. Mole weight: 248.75. Catalog: APB1228837055.
Venetoclax Impurity 9
Venetoclax Impurity 9. Uses: For analytical and research use. Alternative Names: (4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol. CAS No. 1228780-51-5. Molecular formula: C15H19ClO. Mole weight: 250.76. Catalog: APB1228780515.
Venetoclax (Standard)
Venetoclax (Standard) is the analytical standard of Venetoclax. This product is intended for research and analytical applications. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM. Venetoclax induces autophagy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABT-199 (Standard); GDC-0199 (Standard); RG7601 (Standard). CAS No. 1257044-40-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15531R.
Venlafaxine
Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Wy 45030. CAS No. 93413-69-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196.
Venlafaxine
Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as the treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It has seemingly superior efficacy in severe depression as a narcotic and is increasingly used as a measure of last resort for refractory cases. Synonyms: Wy 45030; Wy45030; Wy-45030; Effexor; Elafax. Grade: >98%. CAS No. 93413-69-5. Molecular formula: C17H27NO2. Mole weight: 277.4.
Venlafaxine Acetamide Impurity
Venlafaxine Acetamide Impurity. Uses: For analytical and research use. CAS No. 295366-48-2. Molecular formula: C17H25NO3. Mole weight: 291.39. Catalog: APB295366482.
Venlafaxine Cyano Impurity
Venlafaxine Cyano Impurity. Uses: For analytical and research use. CAS No. 93413-76-4. Molecular formula: C15H19NO2. Mole weight: 245.32. Catalog: APB93413764.
Venlafaxine cyclic impurity
Venlafaxine cyclic impurity. Group: Biochemicals. Alternative Names: 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane. Grades: Highly Purified. CAS No. 93413-70-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H25NO2. US Biological Life Sciences.
Worldwide
Venlafaxine-[d10] Hydrochloride
One of the isotopic labelled form of Venlafaxine HCl, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: D,L-Venlafaxine-d10 Hydrochloride; 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol Hydrochloride-d10. CAS No. 1216539-56-8. Molecular formula: C17H18D10ClNO2. Mole weight: 323.92.
Venlafaxine-[d6] hydrochloride
An isotope labelled derivative of Venlafaxine. Venlafaxine is a selective serotonin-norepinephrine reuptake inhibitor as an antidepressant. Grade: 95% by HPLC; 98% atom D. CAS No. 1062606-12-5. Molecular formula: C17H22D6ClNO2. Mole weight: 319.90.
Venlafaxine EP Impurity A
Venlafaxine EP Impurity A. Uses: For analytical and research use. CAS No. 775-33-7. Molecular formula: C11H17NO. Mole weight: 179.26. Catalog: APB775337.
Venlafaxine EP Impurity A HCl
Venlafaxine EP Impurity A HCl. Uses: For analytical and research use. CAS No. 50822-98-5. Molecular formula: C11H18ClNO. Mole weight: 215.72. Catalog: APB50822985.
Venlafaxine EP Impurity B
Venlafaxine EP Impurity B. Uses: For analytical and research use. CAS No. 323176-93-8. Molecular formula: C14H21NO3. Mole weight: 251.33. Catalog: APB323176938.
Venlafaxine EP Impurity B HCl
Venlafaxine EP Impurity B HCl. Uses: For analytical and research use. CAS No. 2174001-92-2. Molecular formula: C14H22ClNO3. Mole weight: 287.78. Catalog: APB2174001922.
Venlafaxine EP Impurity C
Venlafaxine EP Impurity C. Uses: For analytical and research use. CAS No. 93413-77-5. Molecular formula: C15H23NO2. Mole weight: 249.35. Catalog: APB93413775.
Venlafaxine EP Impurity C HCl
Venlafaxine EP Impurity C HCl. Uses: For analytical and research use. CAS No. 130198-05-9. Molecular formula: C15H24ClNO2. Mole weight: 285.81. Catalog: APB130198059.
Venlafaxine EP Impurity D
Venlafaxine EP Impurity D. Uses: For analytical and research use. CAS No. 149289-30-5. Molecular formula: C16H25NO2. Mole weight: 263.38. Catalog: APB149289305.
Venlafaxine EP Impurity D HCl
Venlafaxine EP Impurity D HCl. Uses: For analytical and research use. CAS No. 93413-90-2. Molecular formula: C16H26ClNO2. Mole weight: 299.84. Catalog: APB93413902.
Venlafaxine EP Impurity E
Venlafaxine EP Impurity E. Uses: For analytical and research use. CAS No. 93413-70-8. Molecular formula: C17H25NO2. Mole weight: 275.39. Catalog: APB93413708.
Venlafaxine EP Impurity E HCl
Venlafaxine EP Impurity E HCl. Uses: For analytical and research use. CAS No. 93413-56-0. Molecular formula: C17H26ClNO2. Mole weight: 311.85. Catalog: APB93413560.
Venlafaxine EP Impurity F
Venlafaxine EP Impurity F. Uses: For analytical and research use. CAS No. 93413-57-1. Molecular formula: C17H25NO. Mole weight: 259.39. Catalog: APB93413571.
Venlafaxine EP Impurity F HCl
Venlafaxine EP Impurity F HCl. Uses: For analytical and research use. CAS No. 93413-79-7. Molecular formula: C17H26ClNO. Mole weight: 295.85. Catalog: APB93413797.
Venlafaxine EP Impurity G
Venlafaxine EP Impurity G. Uses: For analytical and research use. CAS No. 1076199-92-2. Molecular formula: C17H27NO. Mole weight: 261.41. Catalog: APB1076199922.
Venlafaxine EP Impurity G HCl
Venlafaxine EP Impurity G HCl. Uses: For analytical and research use. CAS No. 2108968-20-1. Molecular formula: C17H28ClNO. Mole weight: 297.87. Catalog: APB2108968201.
Venlafaxine EP Impurity H
Venlafaxine EP Impurity H. Uses: For analytical and research use. CAS No. 1329795-88-1. Molecular formula: C24H33NO3. Mole weight: 383.53. Catalog: APB1329795881.
Venlafaxine EP Impurity H HCl
Venlafaxine EP Impurity H HCl. Uses: For analytical and research use. Molecular formula: C24H34ClNO3. Mole weight: 419.99. Catalog: APB10051.
Venlafaxine hydrochloride
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Wy 45030 hydrochloride. CAS No. 99300-78-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-B0196A.
Venlafaxine hydrochloride
Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases. Uses: Antidepressant. Synonyms: Wy-45030; Wy45030; Wy 45030; Effexor hydrochloride; Effexor; VENLAFAXINE HCl; Effexor XR; Trevilor. Grade: >98%. CAS No. 99300-78-4. Molecular formula: C17H28ClNO2. Mole weight: 313.86.
Venlafaxine hydrochloride
Venlafaxine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 99300-78-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Venlafaxine Impurity 10
Venlafaxine Impurity 10. Uses: For analytical and research use. CAS No. 93413-61-7. Molecular formula: C23H31NO2. Mole weight: 353.51. Catalog: APB93413617.
Venlafaxine Impurity 11
Venlafaxine Impurity 11. Uses: For analytical and research use. CAS No. 29903-09-1. Molecular formula: C17H18O3. Mole weight: 270.33. Catalog: APB29903091.
Venlafaxine Impurity 12
Venlafaxine Impurity 12. Uses: For analytical and research use. CAS No. 1346601-14-6. Molecular formula: C25H35NO3. Mole weight: 397.56. Catalog: APB1346601146.
Venlafaxine Impurity 13
Venlafaxine Impurity 13. Uses: For analytical and research use. CAS No. 1346605-18-2. Molecular formula: C16H25NO. Mole weight: 247.38. Catalog: APB1346605182.
Venlafaxine Impurity 15
Venlafaxine Impurity 15. Uses: For analytical and research use. CAS No. 1643948-40-6. Molecular formula: C17H25NO3. Mole weight: 291.39. Catalog: APB1643948406.
Venlafaxine Impurity 19
Venlafaxine Impurity 19. Uses: For analytical and research use. CAS No. 727728-51-0. Molecular formula: C16H23NO2. Mole weight: 261.37. Catalog: APB727728510.
Venlafaxine Impurity 20
Venlafaxine Impurity 20. Uses: For analytical and research use. Molecular formula: C15H23NO. Mole weight: 233.36. Catalog: APB10052.
Venlafaxine Impurity 21
Venlafaxine Impurity 21. Uses: For analytical and research use. CAS No. 272788-07-5. Molecular formula: C16H23NO3. Mole weight: 277.36. Catalog: APB272788075.
Venlafaxine Impurity 39
Venlafaxine Impurity 39. Uses: For analytical and research use. CAS No. 448904-47-0. Molecular formula: C20H31NO6. Mole weight: 381.47. Catalog: APB448904470.
Venlafaxine Impurity 40
Venlafaxine Impurity 40. Uses: For analytical and research use. CAS No. 1062606-12-5. Molecular formula: C17H22D6ClNO2. Mole weight: 319.9. Catalog: APB1062606125.
Venlafaxine Impurity 41
Venlafaxine Impurity 41. Uses: For analytical and research use. CAS No. 2680662-11-5. Molecular formula: C16H24N2O3. Mole weight: 292.38. Catalog: APB2680662115.
Venlafaxine Impurity 5
Venlafaxine Impurity 5. Uses: For analytical and research use. CAS No. 1346600-77-8. Molecular formula: C13H19NO3. Mole weight: 237.3. Catalog: APB1346600778.
Venlafaxine N-Oxide
Venlafaxine N-Oxide is a prodrug. Group: Biochemicals. Alternative Names: 1-[2- (Dimethyloxidoamino) -1- (4-methoxyphenyl) ethyl]cyclohexanol. Grades: Highly Purified. CAS No. 1094598-37-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Venlafaxine Related Compound A
Venlafaxine Related Compound A. Uses: For analytical and research use. CAS No. 93413-90-2. Mole weight: 299.84. Catalog: AP93413902.
Venom antimicrobial peptide-6
Venom antimicrobial peptide-6 is an antimicrobial peptide from Mesobuthus eupeus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Meucin-13; Ile-Phe-Gly-Ala-Ile-Ala-Gly-Leu-Leu-Lys-Asn-Ile-Phe-NH2. Molecular formula: C68H110N16O14. Mole weight: 1375.73.
Venom antimicrobial peptide-9
Venom antimicrobial peptide-9 is an antimicrobial peptide from Mesobuthus eupeus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: meucin-18; Phe-Phe-Gly-His-Leu-Phe-Lys-Leu-Ala-Thr-Lys-Ile-Ile-Pro-Ser-Leu-Phe-Gln.
venombin A
A somewhat thrombin-like enzyme from venoms of snakes of the viper/rattlesnake group. Species variants of the enzyme include ancrod from Agkistrodon rhodostoma (Malayan pit viper) (formerly EC 3.4.21.28), batroxobin from Bothrops atrox (South American pit viper) (formerly EC 3.4.21.29) and crotalase from Crotalus adamanteus (Eastern diamondback rattlesnake) (formerly EC 3.4.21.30). In peptidase family S1 (trypsin family). Does not require activation by Ca2+. Group: Enzymes. Synonyms: α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Enzyme Commission Number: EC 3.4.21.74. CAS No. 146240-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4166; venombin A; EC 3.4.21.74; 146240-35-9; α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Cat No: EXWM-4166.
venombin AB
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin. Group: Enzymes. Synonyms: gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Enzyme Commission Number: EC 3.4.21.55. CAS No. 104003-74-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4147; venombin AB; EC 3.4.21.55; 104003-74-9; gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Cat No: EXWM-4147.
venom exonuclease
Preference for single-stranded substrate. Group: Enzymes. Synonyms: venom phosphodiesterase. Enzyme Commission Number: EC 3.1.15.1. CAS No. 9025-82-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3542; venom exonuclease; EC 3.1.15.1; 9025-82-5; venom phosphodiesterase. Cat No: EXWM-3542.
Venturicidin A
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Aabomycin A1. CAS No. 33538-71-5. Pack Sizes: 1 mg. Product ID: HY-N125722.
Venturicidin A
The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A1. Grade: >95% by HPLC. CAS No. 33538-71-5. Molecular formula: C41H67NO11. Mole weight: 749.97.
Venturicidin B
The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A2; (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one. Grade: >95% by HPLC. CAS No. 33538-72-6. Molecular formula: C40H66O10. Mole weight: 706.94.
Vepafestinib
Vepafestinib (TAS0953/HM06) is a next-generation brain-penetrant, selective and orally active RET inhibitor with an IC50 value of 0.33 nM. Vepafestinib inhibits the phosphorylation of RET and its downstream signaling pathways, thus blocking the growth and signal transduction of tumor cells and inducing cell cycle arrest and apoptosis. Vepafestinib can be used in the research of various RET-driven cancers, such as non-small cell lung cancer, thyroid cancer and other disease areas[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAS0953/HM06. CAS No. 2129515-96-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132846.
Vepdegestrant
Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC50) of about 2 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARV-471. CAS No. 2229711-68-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138642.
VER 155008
VER 155008. Group: Biochemicals. Grades: Purified. CAS No. 1134156-31-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
VER-155008
VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70. Uses: Scientific research. Category: Signaling pathways. CAS No. 1134156-31-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10941.
VER-155008
VER155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78 (HSPA5, Bip), respectively, >100-fold selectivity over HSP90. VER155008 inhibits autophagy and causes reduced levels of HSP90 client proteins. Group: Inhibitors. CAS No. 1134156-31-2. Pack Sizes: 10mg. Product ID: S7751. Formula: C25H23Cl2N7O4. Smiles: C1=CC(=CC=C1COCC2C(C(C(O2)N3C4=NC=NC(=C4N=C3NCC5=CC(=C(C=C5)Cl)Cl)N)O)O)C#N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
VER-246608
VER-246608 is a potent and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50s of 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1684386-71-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12492.
Veraguensin
Veraguensin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19950-55-1. Pack Sizes: 10mg. Molecular Formula: C22H28O5, Molecular Weight: 372.46. US Biological Life Sciences.
Worldwide
Verapamil
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Verapamil; CP-16533-1. CAS No. 52-53-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14275.
Verapamil-d3 hydrochloride
Verapamil-d3 (hydrochloride) is the deuterium labeled Verapamil hydrochloride. Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Verapamil-d3 hydrochloride; CP-16533-1-d3 hydrochloride. CAS No. 2714485-49-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-A0064S.