A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Verruculogen is a tremorgenic mycotoxin and inhibitor of the M phase of the mammalian cell cycle. Verruculogen is produced by Penicillium and Aspergillus species. Verruculogen enhances the binding of ChTX to maxi-k channels with a K1/2 value of 170 nM. Verruculogen inhibits the amplitude of Ca2+-activated K+ currents. Verruculogen induces severe tremors in infected animals[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 12771-72-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6688.
Verruculogen
Verruculogen is a tremorgenic mycotoxin isolated from penicillium verruculosu. It can inhibit the K+ channel activated by ca2+, and is a cell cycle inhibitor that prevents M phase division. Alternative Names: TR 1 toxin. Grades: >95% by HPLC. CAS No. 12771-72-1. Molecular formula: C27H33N3O7. Mole weight: 511.57.
verruculogen prenyltransferase
Found in a number of fungi. Catalyses the last step in the biosynthetic pathway of the indole alkaloid fumitremorgin A. The enzyme from the fungus Neosartorya fischeri is also active with fumitremorgin B and 12α,13α-dihydroxyfumitremorgin C. Group: Enzymes. Synonyms: FtmPT3. Enzyme Commission Number: EC 2.5.1.107. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2723; verruculogen prenyltransferase; EC 2.5.1.107; FtmPT3. Cat No: EXWM-2723.
verruculogen synthase
Requires Fe2+ and ascorbate. Found in the fungus Aspergillus fumigatus. Both atoms of a dioxygen molecule are incorporated into verruculogen. Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A. Group: Enzymes. Synonyms: fmtF (gene name); FmtOx1. Enzyme Commission Number: EC 1.14.11.38. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0656; verruculogen synthase; EC 1.14.11.38; fmtF (gene name); FmtOx1. Cat No: EXWM-0656.
Versatic acid 10
Versatic Acid 10 is a synthetic high-branched-C10 tertiary carboxylic acid containing a total of 10 carbon atoms. Versatic Acid 10 is a key intermediate in the manufacture of a wide range of products and generally exhibits excellent hydrolytic stability and resistance to a variety of chemical agents. Versatic Acid 10 is a very effective metal extractant, especially suitable for nickel. It can also be used as a corrosion inhibitor in synthetic lubricants. Alternative Names: Hexion Versatic acid 10; Neodecanoic acid; Versatic TM Acid 10. Grades: ≥90%.
versatile peroxidase
A hemoprotein. This ligninolytic peroxidase combines the substrate-specificity characteristics of the two other ligninolytic peroxidases, EC 1.11.1.13, manganese peroxidase and EC 1.11.1.14, lignin peroxidase. Unlike these two enzymes, it is also able to oxidize phenols, hydroquinones and both low- and high-redox-potential dyes, due to a hybrid molecular architecture that involves multiple binding sites for substrates. Group: Enzymes. Synonyms: VP; hybrid peroxidase; polyvalent peroxidase; reactive-black-5:hydrogen-peroxide oxidoreductase. Enzyme Commission Number: EC 1.11.1.16. CAS No. 42613-30-9, 114995-15-2. Versatile Peroxidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0497; versatile peroxidase; EC 1.11.1.16; 42613-30-9, 114995-15-2; VP; hybrid peroxidase; polyvalent peroxidase; reactive-black-5:hydrogen-peroxide oxidoreductase. Cat No: EXWM-0497.
Versicolin
Versicolin is originally isolated from Asp. versicolor. It only has antibacterial effect on filamentous fungi, and has no inhibitory effect on yeast-like fungi and bacteria. Alternative Names: 2,3,6-Trihydroxytoluene; Toluene-2,3,6-triol; BRN 2249549; 1-methyl-2,3,6-trihydroxybenzene. CAS No. 4389-44-0. Molecular formula: C7H8O3. Mole weight: 140.14.
Versicolorin A
Versicolorin A is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Alternative Names: Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione; NSC 274542; (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione. Grades: 98%. CAS No. 6807-96-1. Molecular formula: C18H10O7. Mole weight: 338.27.
Versicolorin B
Versicolorin B is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Alternative Names: (3aS,12aR)-4,6,8-trihydroxy-2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione; Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 2,3,3a,12a-tetrahydro-4,6,8-trihydroxy-, cis-(+-)-. CAS No. 4331-22-0. Molecular formula: C18H12O7. Mole weight: 340.28.
versicolorin B synthase
Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: versiconal cyclase; VBS. Enzyme Commission Number: EC 4.2.1.143. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4984; versicolorin B synthase; EC 4.2.1.143; versiconal cyclase; VBS. Cat No: EXWM-4984.
versiconal hemiacetal acetate esterase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA esterase. Enzyme Commission Number: EC 3.1.1.94. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3523; versiconal hemiacetal acetate esterase; EC 3.1.1.94; VHA esterase. Cat No: EXWM-3523.
versiconal hemiacetal acetate reductase
Isolated from the mold Aspergillus parasiticus. Involved in a metabolic grid that leads to aflatoxin biosynthesis. Group: Enzymes. Synonyms: VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Enzyme Commission Number: EC 1.1.1.353. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0269; versiconal hemiacetal acetate reductase; EC 1.1.1.353; VHA reductase; VHA reductase I; VHA reductase II; vrdA (gene name). Cat No: EXWM-0269.
Verteporfin is a potent second-generation photosensitizing agent derived from porphyrin. It is used as a photosensitizer for photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. Verteporfin also suppresses the formation of autophagosome via targeting p62, which binds both polyubiquitinated proteins destined for degradation and LC3 on autophagosomal membranes. Alternative Names: CL 318952; SC 95659; CL318952; SC95659; CL-318952; SC-95659; BPD-MA-A1; (4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid, monomethyl ester. Grades: 95%. CAS No. 129497-78-5. Molecular formula: C41H42N4O8. Mole weight: 718.81.
Verteporfin
Verteporfin is a small molecule that inhibits TEAD-YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Verteporfin is an autophagy inhibitor. Verteporfin inhibits cell proliferation and induces apoptosis. Group: Inhibitors. Alternative Names: CL 318952. CAS No. 129497-78-5. Pack Sizes: 10mg. Product ID: S1786. Formula: C41H42N4O8. Smiles: COC(=O)CCC1=C(C)C2=CC3=NC(=CC4=C(C)C(=C([NH]4)C=C5N=C(C=C1[NH]2)C(=C5C)CCC(O)=O)C=C)C6=CC=C(C(C(=O)OC)C36C)C(=O)OC. Storage Conditions: 3 years-20°C powder.
United States; Europe
Verteporfin
Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis[1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CL 318952. CAS No. 129497-78-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0146.
Vertically Aligned Carbon Nanotube Arrays
Vertically Aligned Carbon Nanotube Arrays.
Verticillin A
Verticillin A is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Alternative Names: [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, (3S,3'S,5aR,5'aR,10bS,10'bS,11S,11'S,11aS,11'aS)-; [10b,10'b(11H,11'H)-Bi-3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone, 2,2',3,3',5a,5'a,6,6'-octahydro-11,11'-dihydroxy-2,2',3,3'-tetramethyl-, [3S-[3α,5aβ,10bβ(3'R*,5'aS*,10'bR*,11'R*,11'aR*),11β,11aα]]-; Verticillin A, (+)-; (6S,6'S)-19,19'-Dideoxy-6,6'-dihydroxychetocin. CAS No. 889640-30-6. Molecular formula: C30H28N6O6S4. Mole weight: 696.84.
Verticillin B
Verticillin B is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Alternative Names: (6S,6'S)-19-Deoxy-6,6'-dihydroxychetocin. CAS No. 52212-86-9. Molecular formula: C30H28N6O7S4. Mole weight: 712.84.
Verticillin C
Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Alternative Names: Verticillin C. Grades: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90.
Vertimycin
It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Alternative Names: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19.
Vertisporin
It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Alternative Names: Spiro[4H-3a,22-(epoxyethano)-10,12-methano-17H,18H-furo[2',3':10,11][1,6]dioxacyclohexadecino[3,4-d][1]benzopyran-11(12H),2'-oxirane]-8,20(5H,22aH)-dione,2,3,10,10a,13a,16-hexahydro-2,3-dihydroxy-10a,15-dimethyl-, (2R,2'S,3R,3aR,6Z,10R,10aS,12R,13aR,17aR,21E,21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59.
Verubecestat
Verubecestat, an iminothiadiazine dioxide compound, is an oral BACE1 inhibitor originated by Merck & Co. It can bind significantly to β-secretase. Verubecestat has the potent effect to treat Alzheimer's disease and is currently in Phase III clinical trials. Uses: Alzheimer's disease. Alternative Names: N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide; J1I0P6WT7T; Verubecestat; UNII-J1I0P6WT7T; J1I0P6WT7T; 1286770-55-5; Verubecestat [USAN]; Verubecestat (USAN/INN); GTPL8699; CHEMBL3301601; SCHEMBL10328722; SCHEMBL17507398; BDBM143220; example 25 (US8940748); SCH-900931; D10739; US8940748, 25; 2-Pyridinecarboxamide, N-(3-((5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoro-; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-1,2,5,6-tetrahydro-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide. Grades: 98%. CAS No. 1286770-55-5. Molecular formula: C17H17F2N5O3S. Mole weight: 409.41.
Verubecestat
Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759.
Verubulin
Verubulin (MPC-6827) is a highly potent and broad-spectrum microtubule blocker. Verubulin has antitumor activity against breast cancer, melanoma, and ovarian cancer. Verubulin can be used in non-small cell lung cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MPC 6827. CAS No. 827031-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14907.
Verucerfont
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively. Verucerfont supresses the CRH-1 receptor to decrease ACTH release following chronic stress. Alternative Names: GSK561679; GSK 561679; GSK-561679; GSK561679A; NBI-77860; NBI 77860; NBI77860; 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 885220-61-1. Molecular formula: C22H26N6O2. Mole weight: 406.49.
Verucerfont
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK561679. CAS No. 885220-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14875.
Verucopeptin
It is an antibiotic produced by the strain of Actinomadura verrucosospora Q886-2. It has weak antimicrobial effect and can prolong the survival time of mice transplanted with melanoma. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Alternative Names: 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide. Grades: 98%. CAS No. 138067-14-8. Molecular formula: C43H73N7O13. Mole weight: 896.08.
very-long-chain 3-oxoacyl-CoA reductase
The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. The enzyme is active with substrates with chain length of C16 to C34, depending on the species. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Enzyme Commission Number: EC 1.1.1.330. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0244; very-long-chain 3-oxoacyl-CoA reductase; EC 1.1.1.330; very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Cat No: EXWM-0244.
very-long-chain 3-oxoacyl-CoA synthase
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids. For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate, while CER6 from the same plant prefers substrates with chain length of C22 to C32. cf. EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA. Enzyme Commission Number: EC 2.3.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2142; very-long-chain 3-oxoacyl-CoA synthase; EC 2.3.1.199; very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA synthase; condensing enzyme (ambiguous); CUT1 (gene name); CER6 (gene name); FAE1 (gene name); KCS (gene name); ELO (gene name). Cat No: EXWM-2142.
This is the third component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: PHS1 (gene name); PAS2 (gene name). Enzyme Commission Number: EC 4.2.1.134. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4975; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; EC 4.2.1.134; PHS1 (gene name); PAS2 (gene name). Cat No: EXWM-4975.
very-long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme is most active toward long-chain acyl-CoAs such as C14, C16 and C18, but is also active with very-long-chain acyl-CoAs up to 24 carbons. It shows no activity for substrates of less than 12 carbons. Its specific activity towards palmitoyl-CoA is more than 10-fold that of the long-chain acyl-CoA dehydrogenase. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.8, long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: ACADVL (gene name). Enzyme Commission Number: EC 1.3.8.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1416; very-long-chain acyl-CoA dehydrogenase; EC 1.3.8.9; ACADVL (gene name). Cat No: EXWM-1416.
very-long-chain enoyl-CoA reductase
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase. Group: Enzymes. Synonyms: TSC13 (gene name); CER10 (gene name). Enzyme Commission Number: EC 1.3.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1363; very-long-chain enoyl-CoA reductase; EC 1.3.1.93; TSC13 (gene name); CER10 (gene name). Cat No: EXWM-1363.
Verzistobart
Verzistobart is an IgG1κ antibody targeting the hepatitis A virus cellular receptor HAVCR2. Uses: Scientific research. Category: Signaling pathways. Alternative Names: INCAGN02390. CAS No. 2649466-18-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P990085.
Vesatolimod
Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC50 of 291 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-9620. CAS No. 1228585-88-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15601.
Vescalagin
Vescalagin. CAS No. 36001-47-5. Molecular formula: C41H26O26. Mole weight: 934.6.
Vesencumab
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MNRP-1685A. CAS No. 1205533-60-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99386.
vesicle-fusing ATPase
A large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger's syndrome. Group: Enzymes. Enzyme Commission Number: EC 3.6.4.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4708; vesicle-fusing ATPase; EC 3.6.4.6. Cat No: EXWM-4708.
Vesicular Stomatitis Virus Nucleoprotein (52-59)
Vesicular Stomatitis Virus Nucleoprotein (52-59) (VSV-8), corresponding to positions 52 to 59 of the vesicular stomatitis virus (VSV) nuclear protein, is expressed in the cytosol of VSV-infected cells. CTL response to VSV in H-2Kb mice is directed against this immunodominant peptide. VSV-8 forms a complex with the mouse MHC Class I molecule H-2Kb, similar to the human HLA Class I. Alternative Names: VSV-8; H-Arg-Gly-Tyr-Val-Tyr-Gln-Gly-Leu-OH; L-Leucine, L-arginylglycyl-L-tyrosyl-L-valyl-L-tyrosyl-L-glutaminylglycyl-; N5-(Diaminomethylene)-L-ornithylglycyl-L-tyrosyl-L-valyl-L-tyrosyl-L-glutaminylglycyl-L-leucine. Grades: ≥95%. CAS No. 132326-74-0. Molecular formula: C44H66N12O12. Mole weight: 955.08.
Vesnarinone
Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 (PDE3) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OPC-8212. CAS No. 81840-15-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15297.
Vespid chemotactic peptide 5e
Vespid chemotactic peptide 5e is an antibacterial peptide isolated from Vespa magnifica. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Phe-Leu-Pro-Ile-Ile-Ala-Lys-Leu-Leu-Gly-Gly-Leu-Leu. Grades: >95%. Molecular formula: C69H118N14O14. Mole weight: 1367.79.
Vespid chemotactic peptide 5f
Vespid chemotactic peptide 5f is an antibacterial peptide isolated from Vespa magnifica. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: H-Phe-Leu-Pro-Ile-Pro-Arg-Pro-Ile-Leu-Leu-Gly-Leu-Leu-OH. Grades: >95%. Molecular formula: C74H124N16O14. Mole weight: 1461.9.
Vespid chemotactic peptide 5g
Vespid chemotactic peptide 5g is an antibacterial peptide isolated from Vespa magnifica. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: H-Phe-Leu-Ile-Ile-Arg-Arg-Pro-Ile-Val-Leu-Gly-Leu-Leu-OH. Grades: >95%. Molecular formula: C75H131N19O14. Mole weight: 1523.
VESP-VB1
VESP-VB1 is an antibacterial peptide isolated from Vespa bicolor. Alternative Names: Phe-Met-Pro-Ile-Ile-Gly-Arg-Leu-Met-Ser-Gly-Ser-Leu. Molecular formula: C64H108N16O16S2. Mole weight: 1421.78.
Vestitol
Vestitol. Group: Biochemicals. Grades: Highly Purified. CAS No. 35878-41-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H16O4. US Biological Life Sciences.
Worldwide
Vestitol
Vestitol isolated from the herb of Lotus corniculatus L. It has phytoalexin activity. Uses: Antimicrobial activity; anti-inflammatory activity. Alternative Names: (3R)-3β-(2-Hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol. Grades: 98.5%. CAS No. 35878-41-2. Molecular formula: C16H16O4. Mole weight: 272.3.
vestitone reductase
This plant enzyme catalyses the penultimate step in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. This activity was previously classified as part of EC 1.1.1.246, pterocarpin synthase, which is now known to be catalysed by two enzymes, vestitone reductase and EC 4.2.1.139, medicarpin synthase. Group: Enzymes. Synonyms: pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Enzyme Commission Number: EC 1.1.1.348. CAS No. 118477-70-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0263; vestitone reductase; EC 1.1.1.348; 118477-70-6; pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Cat No: EXWM-0263.
The initial internal cyclization produces the monocyclic intermediate germacrene A. Group: Enzymes. Synonyms: vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Enzyme Commission Number: EC 4.2.3.21. CAS No. 192465-18-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5178; vetispiradiene synthase; EC 4.2.3.21; 192465-18-2; vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Cat No: EXWM-5178.
Vetiver oil. Alternative Names: Oils, vetiver. CAS No. 8016-96-4. Purity: 0.98. Product ID: CI-EO-0025. Molecular formula: C80H138B4O12. Mole weight: 1335.2 g/mol. Alfa Chemistry - ISO 9001:32057 Certified.
Vetiver Oil - CO2
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Aromatherapy. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-006. Olfactive Profile: Woody, earthy, rooty, smokey, nutty, powdery, sweet. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Haiti
Vetiver Oil Haiti. CAS No. 8016-96-4. Kosher: Y. VIGON Item # 504190. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, Cosmetics.
America & Internationally
Vetiver Oil Java Crude
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Essential Oils. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-001. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Java M.D.
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves. Uses: Perfumery, Cosmetics. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-003. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Java Rectified
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Essential Oils. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-002. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiveryl Acetate
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Fragrance Products. Group: Plant Extracts. INCI Names: Vetiveryl Acetate. Grades: FOOD GRADE. CAS No. 84082-84-8. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-005. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-031-1. FEMA No: 4218. Origin: Indonesia.
Vevorisertib (ARQ 751) trihydrochloride is a selective, allosteric, pan-AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT. Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC50 values of 0.55, 0.81, and 1.3 nM for AKT1, AKT2, and AKT3, respectively. Vevorisertib trihydrochloride can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARQ 751 trihydrochloride. CAS No. 1416775-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137458A.
VGluT1 Antibody [E6H10]
Vesicular Glutamate Transporter 1,VGluT1. Group: Antibodies. Alternative Names: BNPI, VGLUT1, SLC17A7, Vesicular glutamate transporter 1, VGluT1, Brain-specific Na(+)-dependent inorganic phosphate cotransporter, Solute carrier family 17 member 7. CAS No. Pack Sizes: 20uL. Product ID: F3458. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
VGSCs-IN-1
VGSCs-IN-1 is a potent VGSC inhibitor, a 2-piperazine analog of Riluzole that exhibits good blocking activity on Nav1.4.VGSCs-IN-1 can be used to study cellular excitability disorders. Category: Active pharmaceutical ingredients. CAS No. 1204296-79-6. Product ID: API1204296796. Molecular formula: C12H12F3N3OS. Mole weight: 303.3.
VH032
VH032 is a VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. VH032 is a VHL/HIF-1α interaction inhibitor with a Kd
VH 032 amide-alkylC5-azide
VH 032 amide-alkylC5-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2821804-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-163167.
VH032-cyclopropane-F
VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VHL ligand 3; E3 ligase Ligand 19. CAS No. 2306193-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-125905.
VH 032-linker 6
VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Alternative Names: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75.
VH032-PEG5-C6-Cl
VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HaloPROTAC 2. CAS No. 1799506-06-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112495.
VH 101, acid
VH 101, acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH 101, acid contains an E3 ligase ligand plus an alkyl linker with terminal amine ready for conjugation to a target protein ligand[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408341-97-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-47070.