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| Product | Description | |
|---|---|---|
| VT3989 | VT3989 (YAP/TAZ inhibitor-3) is a potent and selective oral inhibitor of TEAD auto-palmitoylation, blocking its interaction with yes-associated protein (YAP). It exhibits antitumor activity and shows potential for treating mesothelioma and solid tumors with NF2 mutations. Group: Inhibitors. Alternative Names: YAP/TAZ inhibitor-3. CAS No. 2506273-81-8. Pack Sizes: 1mg. Product ID: E6486. Formula: C21H18F3NO3. |  United States; Europe |
| VTP-27999 (Hydrochloride) | VTP-27999 Hydrochloride is an orally active renin inhibitor. VTP-27999 Hydrochloride functionally inhibits renin and acid-activated prorenin, suppresses plasma renin activity and modulates plasma and urinary aldosterone levels. VTP-27999 Hydrochloride reduces mean arterial blood pressure, induces plasma renin concentration increases, decreases plasma angiotensin II levels and enhances renin immunoreactivity. VTP-27999 (Hydrochloride) can be used for the research of hypertension and chronic renal disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1264191-73-2. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76652. |  |
| VTP50469 | VTP50469 is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 has potently anti-leukemia activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SNDX-50469. CAS No. 2169916-18-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114162. | |
| VTP50469 | VTP50469 Inhibitor. Uses: Scientific use. Product Category: T13336. CAS No. 2169916-18-9. |  |
| VTP50469 | VTP50469 is a potent, highly selective and orally active inhibitor of Menin-MLL interaction with Ki of 104 pM. VTP50469 exhibits anti-leukemia activity. Group: Inhibitors. CAS No. 2169916-18-9. Pack Sizes: 5mg. Product ID: S8934. Formula: C32H47FN6O4S. Smiles: CC(C)N(C(C)C)C(=O)C1=C(OC2=CN=CN=C2N3CC4(CCN(CC4)CC5CCC(CC5)N[S](C)(=O)=O)C3)C=CC(=C1)F. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| VTP50469 fumarate | VTP50469 fumarate is a potent, highly selective and orally active Menin-MLL interaction inhibitor with a Ki of 104 pM. VTP50469 fumarate has potently anti-leukemia activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SNDX-50469 fumarate. CAS No. 2169919-29-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114162A. | |
| v-Triazolo[4,5-b]pyridine,5,7-dimethyl-(6ci) | v-Triazolo[4,5-b]pyridine,5,7-dimethyl-(6ci). Alternative Names: v-Triazolo[4,5-b]pyridine, 5,7-dimethyl- (6CI);5,7-Dimethyl-v-triazolo[4,5-b]pyridine. CAS No. 114163-51-8. Purity: 96%. Product ID: ACM114163518. Molecular formula: C7H8N4. Mole weight: 148.168. IUPAC Name: 5,7-dimethyl-2H-triazolo[4,5-b]pyridine. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| v-Triazolo[4,5-d]pyrimidine,5-methylamino-(6ci) | v-Triazolo[4,5-d]pyrimidine,5-methylamino-(6ci). Alternative Names: v-Triazolo[4,5-d]pyrimidine, 5-methylamino- (6CI). CAS No. 117890-88-7. Product ID: ACM117890887. Molecular formula: C5H6N6. Alfa Chemistry - ISO 9001:32057 Certified. | |
| VTX-27 | VTX-27 is a selective protein kinase C θ (PKC θ) inhibitor, with Kis of 0.08 nM and 16 nM for PKC θ and PKC δ. Uses: Scientific research. Category: Signaling pathways. CAS No. 1321924-70-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112782. | |
| VU0071063 | VU0071063 is a potent and specific Kir6.2/SUR1 opener (EC50=7.44 μM) and can be used for investigating Kir6.2/SUR1 expressed in the pancreas and brain. VU0071063 inhibits insulin secretion by inducing hyperpolarization of β-cell membrane potential. VU0071063 chemotype has a very steep structure-activity relationships[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 333415-38-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124424. | |
| VU 0155041 | VU 0155041. Group: Biochemicals. Grades: Purified. CAS No. 1093757-42-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| VU 0155041 sodium salt | VU 0155041 sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 1259372-69-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0155069 | VU 0155069. Group: Biochemicals. Grades: Purified. CAS No. 1130067-06-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0238429 | VU 0238429. Group: Biochemicals. Grades: Purified. CAS No. 1160247-92-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0240551 | VU 0240551. Group: Biochemicals. Grades: Purified. CAS No. 893990-34-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0240551 | VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 893990-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16689. | |
| VU 0255035 | VU 0255035. Group: Biochemicals. Grades: Purified. CAS No. 1135243-19-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0255035 | VU0255035 is a highly selective and competitive M1 mAChR antagonist. VU0255035 blocks M1 mAChR signals to reduce epileptic seizures and regulate neuronal membrane potential. VU0255035 can be used in research related to central nervous system diseases, such as epilepsy, Parkinson's disease, and dystonia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU 255035. CAS No. 1135243-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108234. | |
| VU 0285683 | VU 0285683. Group: Biochemicals. Alternative Names: 3-(2-Pyridyl)-5-(3-fluoro-5-cyanophenyl)-1,2,4-oxadiazole. Grades: Highly Purified. CAS No. 327056-22-4. Pack Sizes: 10mg. Molecular Formula: C14H7FN4O, Molecular Weight: 266.23. US Biological Life Sciences. | Worldwide |
| VU 0357017 hydrochloride | VU 0357017 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135242-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU0357017 hydrochloride | VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM). VU0357017 hydrochloride can be used for the research of Alzheimers disease and schizophrenia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CID-25010775. CAS No. 1135242-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19752A. | |
| VU 0357121 | VU 0357121. Group: Biochemicals. Alternative Names: 4-Butoxy-N-(2,4-difluorophenyl)-benzamide. Grades: Highly Purified. CAS No. 433967-28-3. Pack Sizes: 25mg. Molecular Formula: C17H17F2NO2, Molecular Weight: 305.32. US Biological Life Sciences. | Worldwide |
| VU0359595 | VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM). VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CID-53361951; ML-270. CAS No. 1246303-14-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101293. | |
| VU 0360172 | VU 0360172. Group: Biochemicals. Alternative Names: N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg. Molecular Formula: C18H16ClFN2O, Molecular Weight: 330.78. US Biological Life Sciences. | Worldwide |
| VU 0360172 hydrochloride | VU 0360172 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0360223 | VU 0360223. Group: Biochemicals. Grades: Purified. CAS No. 1274859-33-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0361737 | VU 0361737. Group: Biochemicals. Grades: Purified. CAS No. 1161205-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0364439 | VU 0364439. Group: Biochemicals. Grades: Purified. CAS No. 1246086-78-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0364439 | VU 0364439 is a mGlu4 positive allosteric modulator with an EC50 of 19.8 nM. VU 0364439 modulates the GRM4/CBX4/HIF-1α signaling pathway by enhancing GRM4-CBX4 interaction. VU 0364439 can be used for the research of parkinsons disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1246086-78-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15476. | |
| VU0364572 TFA | VU0364572 TFA is an orally active and selective allosteric agonist of the M1 muscarinic receptor with an EC50 of 0.11 μM. VU0364572 TFA has neuroprotective potential for preventing memory impairments and reducing neuropathology in Alzheimers Disease. VU0364572 TFA is CNS penetrant[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1240514-89-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113616A. | |
| VU0364739 | VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1244639-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150412. | |
| VU 0364739 hydrochloride | VU 0364739 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1244640-48-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0364770 | VU 0364770. Group: Biochemicals. Grades: Purified. CAS No. 61350-00-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 0365114 | VU 0365114. Group: Biochemicals. Grades: Purified. CAS No. 1208222-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU041 | VU041 is a first submicromolar-affinity inhibitor of Anopheles (An.) gambiae and Aedes (Ae.) aegypti inward rectifier potassium 1 (Kir1) channels with IC50 values of 2.5 μM and 1.7 μM, respectively. VU041 inhibits appreciably is mammalian Kir2.1 (IC50 of 12.7 μM), and has less inhibitory effect on mammalian Kir1.1, Kir4.1, Kir6.2/SUR1, and Kir7.1. VU041 also induces impaired Malpighian tubule function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 332943-64-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118607. | |
| VU0453379 | VU0453379 is a blood-brain barrier permeable GLP-1R positive allosteric modulator (PAM) with an EC50 value of 1.3 μM. VU0453379 potentiates the actions of endogenous GLP-1 and synthetic peptide agonists, and promotes GLP-1 receptor internalization. VU0453379 stimulates insulin secretion from primary mouse islets. VU0453379 enhances the function of endogenous GLP-1R and reverses catalepsy in animal models. VU0453379 is useful for research on Parkinson's disease and type 2 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1638646-27-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116819. | |
| VU0453595 | VU0453595 is a highly selective, systemically active M1 positive allosteric modulator (PAM, EC50=2140?nM) for the research of schizophrenia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432436-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120023. | |
| VU0463271 | VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1391737-01-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110110. | |
| VU 0463271 | VU 0463271. Group: Biochemicals. Grades: Purified. CAS No. 1391737-01-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU0467154 | VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1451993-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112209. | |
| VU0467319 | VU0467319 (Compound VU319) is a highly selective and blood-brain-permeable, orally active M1 positive allosteric modulator (PAM) (EC50: 492 nM). VU0467319 is selective (EC50 > 30 μM) versus M2-5 for both human and rat. VU0467319 improves cognitive impairment in Alzheimer's disease (AD) through central M1 muscarinic receptors. VU0467319 does not induce cholinergic adverse reactions and has potential in AD research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU319. CAS No. 1432438-14-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173396. | |
| VU0486846 | VU0486846 is an orally active and selective muscarinic acetylcholine receptor M1 positive allosteric modulator (PAM) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1788055-11-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121806. | |
| VU0514009 | VU0514009 is a competitive chemokine-like receptor 1 (CMKLR1) antagonist (EC50=2 nM). VU0514009 prevents chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux response in HEK293 cells. VU0514009 is promising for research of inflammatory diseases and metabolic syndrome[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 932973-77-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-174140. | |
| VU0529331 | VU0529331 is a homomeric GIRK channel activator, with an EC50 value of 5.1 μM for human GIRK2 and an EC50 value of 22.3 μM for GIRK4. VU0529331 serves as a starting point for the development of non-GIRK1/X channel probes and also acts as a tool for studying homomeric GIRK channels. VU0529331 is applicable to research related to addiction, primary aldosteronism and delayed-onset obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1286725-49-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112705. | |
| VU0542270 | VU0542270 is a selective vascular Kir6.1/SUR2B KATP channel inhibitor with an IC50 value of 100 nM. VU0542270 has an IC50 > 30 μM for the other nine members of the Kir channel family. VU0542270 can be used in the study of cardiovascular disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1396814-79-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162322. | |
| VU0546110 | VU0546110 is a selective inhibitor of the sperm-specific potassium channel SLO3, with IC50s of 1.287 μM (SLO3) and 59.80 μM (SLO1) in HEK293 cells, respectively. VU0546110 blocks heterologous SLO3 currents and endogenous K+ currents in human sperm. VU0546110 halts sperm hyperpolarization, induced acrosome reaction, and hyper-activated motility. VU0546110 has contraceptive potential[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1421523-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg. Product ID: HY-164911. | |
| VU0650786 | VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809085-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108710. | |
| VU 10010 | VU 10010. Group: Biochemicals. Grades: Purified. CAS No. 633283-39-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 152100 | VU 152100. Group: Biochemicals. Grades: Purified. CAS No. 409351-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 1545 | VU 1545. Group: Biochemicals. Grades: Purified. CAS No. 890764-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 29 | VU 29. Group: Biochemicals. Grades: Purified. CAS No. 890764-36-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU-29 | VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor (EC50=9 nM and Ki=244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 890764-36-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107508. | |
| VU 590 dihydrochloride | VU 590 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 313505-85-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU 591 hydrochloride | VU 591 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1315380-70-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VU6001966 | VU6001966 is a brain-penetrant and selective mGlu2 receptor inhibitor. VU6001966 blocks mGlu2 receptor activity, counteracts LY379268 (HY-103558)-mediated blood-brain barrier protection and inflammatory cytokine dampening in microglia under inflammatory conditions. VU6001966 enhances antidepressant effects when combined with Scopolamine (HY-N0296). VU6001966 can be used for the research of major depressive disorder[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2009052-76-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg. Product ID: HY-120717. | |
| VU6010572 | VU6010572 is a potent, selective and brain-penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM. VU6010572 is highly CNS penetrant[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126784-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122138. | |
| VU6015929 | VU6015929 is a potent, selective and orally active dual discoidin domain receptor 1/2 (DDR1/2) inhibitor with IC50s of 4.67 nM and 7.39 nM, respectively. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2442597-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135401. | |
| VU6019650 | VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR (IC50=36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopaminergic reward circuitry. VU6019650 blocks Oxotremorine M iodide (HY-101372A) induced increases of neuronal firing rates of midbrain dopamine neurons in the ventral tegmental area (VTA)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2926782-31-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148502. | |
| VU6028418 | VU6028418 is a potent, highly selective and orally bioavailable M4 mAChR antagonist with an IC50 of 4.1 nM against hM4[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2649803-05-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141711. | |
| VUAA1 | VUAA1 is an insect odorant co-receptor (Orco) agonist. VUAA1 activates both heteromeric and homomeric Orco-containing channels. VUAA1 can disrupt the destructive behaviors of nuisance insects. VUAA1 can be used for insect olfactory research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 525582-84-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125982. | |
| VUANT1 | VUANT1 (VU0183254) is an allosteric antagonist of insect odorant receptor ion channels, which has the activity of inhibiting insect odorant receptor signaling. VUANT1 can inhibit the activation of insect odorant receptors through allosteric regulation, which is important for the study of the molecular mechanism of insect olfactory signaling. Although it may be of limited use in insect control programs, it can be used as a pharmacological tool to study related mechanisms. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VU0183254. CAS No. 663212-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118967. | |
| VUBI1 | VUBI1 (SOS1 activator 1) is a benzimidazole derivative and SOS1 activator with a Kd of 44 nM. VUBI1 can significantly activate RAS-GTP and regulate the phosphorylation of ERK. VUBI1 also can serve as a target ligand for synthesizing PROTACs, such as PROTAC SOS1 degrader-1 (HY-145737), to induce SOS1 degradation. VUBI1 can be used in the study of cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SOS1 activator 1. CAS No. 2245237-53-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-111671. | |
| Vudalimab | Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XMAB-20717. CAS No. 2329669-72-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99166. | |
| VUF 10166 | VUF 10166. Group: Biochemicals. Grades: Purified. CAS No. 155584-74-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VUF 10460 | VUF 10460. Group: Biochemicals. Grades: Purified. CAS No. 1028327-66-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VUF11207 | VUF11207 (Compound 29) is a CXCR7 agonist and a high-potency CXCR7 (pKi of 8.1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8.8) and subsequent internalization (pEC50 of 7.9) of CXCR7[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1378524-41-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100677. | |
| VUF 11207 fumarate | VUF 11207 fumarate. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VUF11207 fumarate | VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1785665-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110318. | |
| VUF 5574 | VUF 5574. Group: Biochemicals. Grades: Purified. CAS No. 280570-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| VUF 5681 dihydrobromide | VUF 5681 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 639089-06-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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