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| Product | Description | |
|---|---|---|
| Vobarilizumab | Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALX-0061. CAS No. 1628814-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99385. |  |
| Vobramitamab | Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. MGC018 displays potent antitumor activity in preclinical tumor models of breast, ovarian, and lung cancer, as well as melanoma[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AEX-4089; MGC026 antibody. CAS No. 2490556-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99101. | |
| Vociprotafib | Vociprotafib (RMC-4630) is an orally active, selective and potent phosphatase SHP2 inhibitor, which blocks activation of the RAS-RAF-MEK-ERK signaling pathway with antitumor activity. Vociprotafib accelerates the time to, and increases the magnitude of, tumor regressions in Osimertinib (HY-15772)-sensitive EGFR-mutant tumors of mice[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RMC-4630; SHP2-IN-7. CAS No. 2172652-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141523. | |
| Voclosporin | Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISAtx-247. CAS No. 515814-01-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106638. | |
| Voclosporin | Voclosporin, a structurally similar analogue of cyclosporin A, is a new type of calcineurin inhibitor. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 515814-01-4. Product ID: API515814014. Molecular formula: C63H111N11O12. Mole weight: 1214.65. Standard: GMP. |  |
| Voclosporine | Voclosporine is an orally available calcineurin inhibitor and potent immunosuppressant used in combination with mycophenolate mofetil and corticosteroids for the treatment of acute lupus nephritis. Uses: A new agent for the treatment of noninfectious uveitis. Alternative Names: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; ISATX 247; R 1524; trans-ISA 247; Voclosporin; Luveniq; Lupkynis; 1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)nona-6,8-dienoyl][(2S)-2-aminobutanoyl]-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]. Grades: 98%. CAS No. 515814-01-4. Molecular formula: C63H111N11O12. Mole weight: 1214.62. |  |
| Vofatamab | Vofatamab (B-701) is an anti-FGFR3 monoclonal antibody (mAb). Vofatamab blocks activation of both the wildtype and genetically activated receptor. Vofatamab can be used in the research of metastatic urothelial carcinoma (mUC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: B-701; MFGR-1877S; RG-7444. CAS No. 1312305-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99384. | |
| Vofopitant dihydrochloride | Vofopitant dihydrochloride (GR 205171A) is a blood-brain barrier-permeable NK1 receptor inhibitor with a pKi of 9.02 in mice. Vofopitant dihydrochloride blocks vomiting-related responses and inhibits pseudoptyalism. Vofopitant dihydrochloride exerts anxiolytic effects, regulates 5-HT receptor function and increases central 5-HT release. Vofopitant dihydrochloride improves hyperarousal symptoms of post-traumatic stress disorder. Vofopitant dihydrochloride can be used in research related to depression, anxiety, vomiting and postoperative nausea and vomiting[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GR 205171A. CAS No. 168266-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12143. | |
| Vofopitant dihydrochloride | Vofopitant dihydrochloride. Alternative Names: 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-;3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S-cis)-;GR 2. CAS No. 168266-51-1. Product ID: ACM168266511. Molecular formula: C21H23F3N6O2HCl. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Voglibose | Voglibose is an alpha-glucosidase inhibitor that is taken orally to improve diabetic postprandial hyperglycemia. Category: Active pharmaceutical ingredients. CAS No. 83480-29-9. Product ID: API83480299. Molecular formula: C10H21NO7. Mole weight: 267.28. Standard: JP/CP. | |
| Voglibose | Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83480-29-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0025. | |
| Voglibose | Voglibose. Group: Biochemicals. Grades: Purified. CAS No. 83480-29-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Voglibose Impurity 1 | Voglibose Impurity 1. Uses: For analytical and research use. CAS No. 6564-72-3. Molecular formula: C34H36O6. Mole weight: 540.66. Catalog: APB6564723. |  |
| Voglibose Impurity 10 | Voglibose Impurity 10. Uses: For analytical and research use. CAS No. 911439-19-5. Molecular formula: C35H36O6. Mole weight: 552.67. Catalog: APB911439195. | |
| Voglibose Impurity 11 | Voglibose Impurity 11. Uses: For analytical and research use. CAS No. 306968-48-9. Molecular formula: C35H36O6. Mole weight: 552.67. Catalog: APB306968489. | |
| Voglibose Impurity 12 | Voglibose Impurity 12. Uses: For analytical and research use. Molecular formula: C22H41NO17. Mole weight: 591.56. Catalog: APB11412. | |
| Voglibose Impurity 13 | Voglibose Impurity 13. Uses: For analytical and research use. Molecular formula: C22H41NO17. Mole weight: 591.56. Catalog: APB11413. | |
| Voglibose Impurity 14 | Voglibose Impurity 14. Uses: For analytical and research use. Molecular formula: C22H41NO17. Mole weight: 591.56. Catalog: APB11414. | |
| Voglibose Impurity 16 | Voglibose Impurity 16. Uses: For analytical and research use. Molecular formula: C10H21NO7. Mole weight: 267.28. Catalog: APB11415. | |
| Voglibose Impurity 17 | Voglibose Impurity 17. Uses: For analytical and research use. Molecular formula: C10H21NO8. Mole weight: 283.28. Catalog: APB11416. | |
| Voglibose Impurity 18 | Voglibose Impurity 18. Uses: For analytical and research use. Molecular formula: C16H31NO12. Mole weight: 429.42. Catalog: APB11417. | |
| Voglibose Impurity 19 | Voglibose Impurity 19. Uses: For analytical and research use. Molecular formula: C22H41NO17. Mole weight: 591.56. Catalog: APB11418. | |
| Voglibose Impurity 2 | Voglibose Impurity 2. Uses: For analytical and research use. CAS No. 1303996-67-9. Molecular formula: C17H34N2O11. Mole weight: 442.26. Catalog: APB1303996679. | |
| Voglibose Impurity 20 | Voglibose Impurity 20. Uses: For analytical and research use. Molecular formula: C22H41NO17. Mole weight: 591.56. Catalog: APB11419. | |
| Voglibose Impurity 3 | Voglibose Impurity 3. Uses: For analytical and research use. CAS No. 1303996-66-8. Molecular formula: C17H34N2O11. Mole weight: 442.26. Catalog: APB1303996668. | |
| Voglibose Impurity 4 | Voglibose Impurity 4. Uses: For analytical and research use. CAS No. 4132-28-9. Molecular formula: C34H36O6. Mole weight: 540.66. Catalog: APB4132289. | |
| Voglibose Impurity 5 | Voglibose Impurity 5. Uses: For analytical and research use. CAS No. 115250-39-0. Molecular formula: C38H45NO7. Mole weight: 627.32. Catalog: APB115250390. | |
| Voglibose Impurity 6 | Voglibose Impurity 6. Uses: For analytical and research use. CAS No. 83465-22-9. Molecular formula: C7H15NO5. Mole weight: 193.2. Catalog: APB83465229. | |
| Voglibose Impurity 7 | Voglibose Impurity 7. Uses: For analytical and research use. Molecular formula: C10H21NO7. Mole weight: 267.28. Catalog: APB11409. | |
| Voglibose Impurity 8 | Voglibose Impurity 8. Uses: For analytical and research use. Molecular formula: C10H21NO7. Mole weight: 267.28. Catalog: APB11411. | |
| Voglibose Impurity 9 | Voglibose Impurity 9. Uses: For analytical and research use. Molecular formula: C10H21NO7. Mole weight: 267.28. Catalog: APB11410. | |
| Volagidemab | Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REMD-477; AMG-477. CAS No. 1233956-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99383. | |
| Volanesorsen | Volanesorsen (ISIS 304801) is an antisense oligonucleotide inhibitor of apolipoprotein CIII (apo-CIII) mRNA that reduces triglyceride levels and improves insulin resistance. Volanesorsen is being studied in the treatment of hypertriglyceridemia, familial chylosiderosis syndrome, and type 2 diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 304801. CAS No. 915430-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145727. | |
| Volanesorsen | Volanesorsen is an antisense oligonucleotide thay targes Apolipoprotein C-III (APOC3) mRNA. Volanesorsen is used for the study of familial chylomicronemia syndrome. CAS No. 915430-78-3. Molecular formula: C230H320N63O125P19S19. Mole weight: 7165.05. | |
| Volanesorsen sodium | Volanesorsen (ISIS 304801) sodium is an antisense oligonucleotide inhibitor of apolipoprotein CIII (apo-CIII) mRNA that reduces triglyceride levels and improves insulin resistance. Volanesorsen sodium is being studied in the treatment of hypertriglyceridemia, familial chylosiderosis syndrome, and type 2 diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ISIS 304801 sodium. CAS No. 1573402-50-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145727A. | |
| Volara Type 2A Closed-Cell Foam | Our Volara 2A foam is a versatile cross-linked LDPE foam with excellent chemical resistance. Volara 2A is highly flexible and finely perforated to fit curves and is used as an insulating liner on vehicle paneling. This variety of foam is commonly used in construction gap fillers, industrial gaskets, custom packaging, floor liners and bottle cap liners as it can be used for food contact. |  |
| VolaraType 4EO Closed-Cell Foam | Volara 4E0 is an EVA copolymer material that offers excellent tensile strength and tear resistance, making the product more durable and tougher. For this reason, 4E0 becomes an excellent alternative to 2A when the foam is subject to greater flexing or twisting during use, making it a viable option for certain impact protection and insulation linings for moving machine parts. Due to the overall nature of the material, this EVA copolymer foam is ideal for use in medical devices and applications designed for skin contact. | |
| Volasertib | BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk) with an IC50 of 0.87 nM and EC50 of 11-37 nM on a panel of cancer cell lines, which exhibited significant anti-proliferative in multiple cancer models, including a model of taxane-resistant colorectal cancer. BI 6727 (Volasertib) caused programmed cell death in colon and non-small cell lung cancer cells both in vitro and in vivo. Alternative Names: Volasertib; BI-6727; BI6727; BI 6727. Grades: 0.98. CAS No. 755038-65-4. Molecular formula: C34H50N8O3. Mole weight: 618.827. | |
| Volasertib | Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BI 6727. CAS No. 755038-65-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12137. | |
| Volasertib (BI6727) | Volasertib is a highly potent Plk1 inhibitor with IC50 of 0.87 nM in a cell-free assay. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Volasertib induces cell cycle arrest and apoptosis in various cancer cells. Phase 3. Group: Inhibitors. Alternative Names: BI 6727. CAS No. 755038-65-4. Pack Sizes: 5mg. Product ID: S2235. Formula: C34H50N8O3. Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Volatile acid mixture | Volatile acid mixture. Group: Others. Appearance: Liquid. Storage: 4-8°C. Volatile acid mixture; GC; Volatile Acid Mixture (qualitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-128. |  |
| Volinanserin | Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MDL100907; M 100907. CAS No. 139290-65-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14940. | |
| Volinanserin-d4 Hydrochloride Salt | A labeled serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907-d4; M 100907-d4; MDL 100907-d4; R-MDL 100907-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Volinanserin Hydrochloride Salt | A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907; M 100907; MDL 100907; R-MDL 100907. Grades: Highly Purified. CAS No. 139290-65-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Volociximab | Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M200; Eos 200-4. CAS No. 558480-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99333. | |
| Volrustomig | Volrustomig (MEDI-5752) is a human IgG1 κ monoclonal antibody targeting CTLA4/PD1. The isotype control for Volrustomig is Human IgG1 kappa, Isotype Control (HY-P99001). Volrustomig anchors to the surface of T cells by binding PD-1, induces PD-1 internalization and degradation, and preferentially inhibits CTLA-4 on activated PD-1+ T cells. Volrustomig binds to tumor-infiltrating lymphocytes and a subset of PD-1+ B cells, enhances T cell function and IFNγ secretion. Volrustomig reduces the activation of non-tumor-infiltrating lymphocytes and exhibits manageable toxicity. Volrustomig can be used in research on various cancers, such as non-small cell lung cancer, gastric cancer, hepatobiliary cancer, and cervical cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI-5752. CAS No. 2407760-40-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990690. | |
| Vomicine | Vomicine. Group: Biochemicals. Alternative Names: Strychnicine; Struxine. Grades: Plant Grade. CAS No. 125-15-5. Pack Sizes: 10mg. Molecular Formula: C22H24N2O4, Molecular Weight: 380.437. US Biological Life Sciences. | Worldwide |
| Vomicine | Vomicine is a natural alkaloid compound found in several plants. Alternative Names: 12-Hydroxy-N-methylpseudostrychinine;4-Hydroxy-19-methyl-16,19-secostrychinidine-10,16-dione;Strychnicine. Grades: >95%. CAS No. 125-15-5. Molecular formula: C22H24N2O4. Mole weight: 380.44. | |
| Vomicine | Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 125-15-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2616. | |
| Vomifoliol | Vomifoliol isolated from the herbs of Vitis vinifera. Alternative Names: (1S)-1-Hydroxy-1-[(1E,3R)-3-hydroxy-1-butenyl]-2,6,6-trimethyl-2-cyclohexene-4-one; (6S,9R)-vomifoliol. Grades: 0.97. CAS No. 23526-45-6. Molecular formula: C13H20O3. Mole weight: 224.3. | |
| vomifoliol dehydrogenase | Oxidizes vomifoliol to dehydrovomifoliol; involved in the metabolism of abscisic acid in Corynebacterium sp. Group: Enzymes. Synonyms: vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Enzyme Commission Number: EC 1.1.1.221. CAS No. 94949-18-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0127; vomifoliol dehydrogenase; EC 1.1.1.221; 94949-18-5; vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Cat No: EXWM-0127. | |
| vomilenine glucosyltransferase | The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions. Group: Enzymes. Synonyms: UDPG:vomilenine 21-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.219. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2447; vomilenine glucosyltransferase; EC 2.4.1.219; UDPG:vomilenine 21-β-D-glucosyltransferase. Cat No: EXWM-2447. | |
| vomilenine reductase | Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.32. CAS No. 462127-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1514; vomilenine reductase; EC 1.5.1.32; 462127-03-3. Cat No: EXWM-1514. | |
| Vonafexor | Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFNα. Vonafexor can be used for anti-HBV research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EYP001. CAS No. 1192171-69-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109197. | |
| Vonlerolizumab | Vonlerolizumab (Pogalizumab; MOXR 0916) is a humanized IgG1 monoclonal antibody targeting OX40 (CD134). Pogalizumab partially blocks the interaction between OX40 and its natural ligand OX40L upon binding, thereby activating the NF-κB signaling pathway. Pogalizumab enhances T cell activation and proliferation and has shown antitumor activity in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pogalizumab; MOXR 0916. CAS No. 1638935-72-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99249. | |
| Vonoprazan | Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. It is used to treat acid-related diseases. It can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori. It is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date in vitro. It inhibits basal gastric acid secretion in a dose-dependent manner, and the ID50 value is 1.26 mg/kg in vivo. It shows a potent and longer-lasting inhibitory effect on the histamine-stimulated gastric acid secretion in rats and dogs. It shows significant antisecretory activity through high accumulation and slow clearance from the gastric tissue. It is unaffected by the gastric secretory state. It was developed by Takeda and Otsuda together. It has been listed. Uses: Vonoprazan is used to treat acid-related diseases. it can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of helicobacter pylori. Alternative Names: TAK-438 free base;TAK438 free base; TAK 438 free base; Takecab;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;1H-Pyrrole-3-m | |
| Vonoprazan-[d3] | Vonoprazan-[d3] is a labelled Vonoprazan, a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Alternative Names: Vonoprazan-d3. Molecular formula: C17H13D3FN3O2S. Mole weight: 348.4. | |
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-15295. | |
| Vonoprazan Fumarate | TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Alternative Names: 1H-Pyrrole-3-methanamine, 5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-, (2E)-2-butenedioate (1:1); TAK438; TAK-438; TAK 438; 5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine (2E)-2-butenedioate (1:1); TAK 438 monofumarate; Takecab; Vocinti; Vonoprazan monofumarate. Grades: 98%. CAS No. 881681-01-2. Molecular formula: C17H16FN3O2S.C4H4O4. Mole weight: 461.46. | |
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19 nM at pH 6.5. Category: Active pharmaceutical ingredients. Synonyms: TAK-438. CAS No. 881681-01-2. Product ID: API881681012. Molecular formula: C21H20FN3O6S. Mole weight: 461.46. | |
| Vonoprazan Fumarate Impurity 4 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 2169271-28-5. Molecular formula: C16H13FN2O3S. Mole weight: 332.35. | |
| Vonoprazan Fumarate Impurity L | Vonoprazan Fumarate Impurity L. Uses: For analytical and research use. Molecular formula: C21H22FN3O6S. Mole weight: 463.48. Catalog: APB10065. | |
| Vonoprazan Impurity 1 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: N-Methyl-1-(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine; 1H-Pyrrole-3-methanamine, N-methyl-5-phenyl-1-(3-pyridinylsulfonyl)-; N-Methyl-5-phenyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine. CAS No. 881732-90-7. Molecular formula: C17H17N3O2S. Mole weight: 327.41. | |
| Vonoprazan Impurity 10 | Vonoprazan Impurity 10. Uses: For analytical and research use. Molecular formula: C16H9ClFN3O2S. Mole weight: 361.78. Catalog: APB10062. | |
| Vonoprazan Impurity 14 | Vonoprazan Impurity 14. Uses: For analytical and research use. CAS No. 1807642-39-2. Molecular formula: C16H10FN3O2S. Mole weight: 327.33. Catalog: APB1807642392. | |
| Vonoprazan Impurity 14 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde; 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde. Grades: ≥95%. CAS No. 881677-11-8. Molecular formula: C16H11FN2O3S. Mole weight: 330.34. | |
| Vonoprazan Impurity 15 | Vonoprazan Impurity 15. Uses: For analytical and research use. CAS No. 2169271-28-5. Molecular formula: C16H13FN2O3S. Mole weight: 332.35. Catalog: APB2169271285. | |
| Vonoprazan Impurity 17 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Alternative Names: 1883595-38-7; 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-Vonoprazan Impurity 17CS-0163877. Grades: 95%. CAS No. 1883595-38-7. Molecular formula: C11H8FNO2. Mole weight: 205.18. | |
| Vonoprazan Impurity 19 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 881674-58-4. Molecular formula: C11H10FNO. Mole weight: 191.20. | |
| Vonoprazan Impurity 19 | Vonoprazan Impurity 19. Uses: For analytical and research use. CAS No. 161958-62-9. Molecular formula: C11H9NO2. Mole weight: 187.2. Catalog: APB161958629. | |
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